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All Journal HAYATI Journal of Biosciences Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Pharmaciana: Jurnal Kefarmasian Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Jurnal Fitofarmaka Indonesia Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Kesehatan Medika Saintika JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun NERS Jurnal Keperawatan JFIOnline Majalah Kedokteran Andalas Health and Medical Journal Real in Nursing Journal JPK: Jurnal Proteksi Kesehatan Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmaceutical Sciences and Research (PSR) Jurnal Kedokteran Hewan Jurnal Farmasi Indonesia Journal of Pharmaceutical and Sciences. Jurnal Riset Multidisiplin dan Inovasi Teknologi Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Akademika Baiturrahim Jambi
Fatma Sri Wahyuni
Fakultas Farmasi, Universitas Andalas, Kampus Limau Manis, Padang, Sumatera Barat, Indonesia
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Analisis Pelayanan Resep Konvensional dan Elektronik serta Pengaruhnya terhadap Kualitas Pelayanan Kefarmasian di RSUD M. Natsir Solok Indonesia Adrizal, Adrizal; Sriwahyuni, Fatma; Aldi, Yufri
JSFK (Jurnal Sains Farmasi & Klinis) Vol 6 No 3 (2019): J Sains Farm Klin 6(3), Desember 2019
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.6.3.195-199.2019

Abstract

Rumah Sakit wajib memberikan pelayanan yang berkualitas sesuai dengan Standar Pelayanan Minimal (SPM) yang telah di tetapkan. Upaya untuk meningkatkan kualitas pelayanan kefarmasian di rumah sakit dapat dilakukan dengan penerapan peresepan elektronik. Penelitian bertujuan untuk mengetahui perbedaan kualitas pelayanan kefarmasian antara peresepan konvensional dan peresepan elektronik. Desain penelitian adalah observasional analitik dengan rancangan cross sectional study. Sampel berjumlah 431 resep diambil dengan teknik random sampling. Uji statistik pada variabel waktu tunggu dan kepuasan pasien yaitu uji t–independen sedangkan variabel kesalahan pemberian obat dan kesesuaian resep dengan formularium digunakan  uji  chi_square dengan tingkat kemaknaan 0,05. Hasil penelitian menunjukan terdapat perbedaan waktu tunggu (p value:0,000), kepuasan pasien (p value:0,000) dan kesesuaian resep dengan formularium (p value:0,000) antara peresepan elektronik dengan peresepan konvensional. Namun tidak terdapat perbedaan kejadian kesalahan pemberian obat antara peresepan elektronik dengan peresepan konvensional (p value:0,063). Penelitian ini menunjukkan bahwa kualitas pelayanan kefarmasian pada peresepan elektronik lebih baik dibandingkan dengan peresepan konvensional. Pimpinan dan manajerial RSUD M.Natsir hendaknya mengimplementasikan peresepan elektronik ini pada instalasi rawat jalan dan rawat inap sehingga kualitas pelayanan kefarmasian dapat ditingkatkan.
Wound-Healing Effect of Ethyl Acetate Subfraction Ointment from Meniran Leaves (Phyllathus niruri L.) at 5% Concentration on White Male Rats Tobat, Sanubari Rela; Wahyuni, Fatma Sri; Yenny, Satya Wydya; MYH, Etriyel; Annisa, Annisa; Wardi, Epi Supri; Fendri, Sandra Tri Juli
Jurnal Riset Multidisiplin dan Inovasi Teknologi Том 3 № 01 (2025): Jurnal Riset Multidisiplin dan Inovasi Teknologi
Publisher : PT. Riset Press International

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59653/jimat.v3i01.1478

Abstract

A study has been conducted on the healing effect of excision wounds using subfraction ointment of ethyl acetate of meniran leaves (Phyllathus niruri L.) with a concentration of 5% on the percentage of wound healing area, epithelialization time, and hydroxyproline levels in male white rats. This study consisted of 3 groups of rats based on ointment grouping, and each group consisted of 15 rats; from 15 rats, they were grouped again into 3 groups based on the day of taking the results of the wound healing parameters, namely days (5, 10 and 15); each group consisted of 5 rats, where group 1 was control with the administration of ointment base, group 2 was given (T® ointment) as a comparison, and group 3 was treated with the administration of the test preparation topically with subfraction ethyl acetate concentration of 5%. Each group was observed and measured for the percentage of wound healing area, epithelialization time, and hydroxyproline levels on days 5, 10, and 15. The results of data analysis using one-way ANOVA and two-way ANOVA followed by Duncan's test (SPSS 23.0) showed a significant difference between the control group and the treatment group in terms of the percentage of wound healing area, epithelialization time and hydroxyproline levels (p<0.05), so it can be concluded that the preparation of ethyl acetate subfraction ointment of meniran leaves with a concentration of 5% has an effect as an excision wound therapy.
Hubungan Sosiodemografi dengan Hasil Klinis Pasien Covid-19 di RSUD Bengkulu Lukas, Stefanus; Ramatillah, Diana Laila; Aldi, Yufri; Wahyuni, Fatma Sri; Gloria, Fransisca; Michael, Michael; Wahyudi, Agung Aji; Astari, Lita Tri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 1 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (411.839 KB) | DOI: 10.35617/jfionline.v14i1.59

Abstract

Coronavirus disease 2019 (Covid-19) adalah penyakit menular yang disebabkan oleh SARS-CoV-2 yang memiliki bentuk dan perilaku menyerupai virus SARS. Persentase angka kematian nasional adalah 4,23, yang berada di atas angka kematian rata-rata nasional. Tujuan penelitian untuk mengetahui faktor-faktor apa saja yang berhubungan dengan kematian pasien Covid-19 di RS Pemerintah Bengkulu.Dengan tujuan Mengetahui hubungan sosiodemografi dengan luaran klinis pasien COVID-19 di Bengkulu.dengan metode Penelitian kohort retrospektif dilakukan dalam penelitian ini. Penelitian ini hanya melibatkan pasien terkonfirmasi COVID-19, dengan total sampel 127 pasien yang dirawat di rumah sakit selama April, Mei, dan Juni 2021.Dan mendapatkan hasil Semua pasien yang dirawat di Rumah Sakit Pemerintah Bengkulu antara April dan Juni 2021 menggunakan azitromisin atau levofloxacin + oseltamivir + vitamin sebagai pengobatan. Hasil dari infeksi covid-19 memiliki beberapa faktor korelasi yang signifikan: usia (0,0001), pekerjaan (0,0001) dan penyakit penyerta (0,0001). Kesimpulan Outcome klinis terburuk paling banyak ditemukan pada pasien yang menderita Diabetes dan berusia lebih dari 50 tahun.
Evaluasi Hasil Klinis Pada Tim Medis yang Mendapat Vaksinasi Booster di Rumah Sakit Bengkayang Kalimantan Barat Lukas, Stefanus; Ramatillah, Diana Laila; Aldi, Yufri; Wahyuni, Fatma Sri; Paulina, Ida; Gloria, Fransisca; Michael, Michael
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.685 KB) | DOI: 10.35617/jfionline.v14i2.70

Abstract

Abstract: In reducing the risk of transmission to health workers, the Government has given the 3rd Booster Covid-19 Vaccination since August 2021. This study uses the Astra Zeneca Vaccine, Moderna Vaccine and Pfizer Vaccine. The purpose of this study was to evaluate the effectiveness of the 3rd Booster vaccine and the clinical outcomes of post-vaccination health workers at West Kalimantan Hospital. Research method Observational Cross-sectional Prospective by conducting questionnaires and interviewing health workers. Samples were taken by convenience sampling and statistical analysis of chis-square. The research instrument used a questionnaire distributed in the hospital. In the study, it was found that as many as 12.60% (14 out of 118 health workers) were infected with Covid-19. The habit that influenced the effectiveness of the 3rd booster vaccination was sunbathing (p <0.05). The low severity of health workers infected with Covid-19 after the 3rd booster vaccine can be seen from the place of treatment, namely 97% independent isolation, 60% without using antivirals and 77% without using antibiotics. The type of vitamin that is most widely used is vitamin C. Hence with this booster vaccination aims to prevent and reduce the severity of patients who contract Covid-19 after vaccination.
Kepemimpinan Kepala Ruangan dan Kepuasan Kerja Perawat Pelaksana Yulia, Revi; Wahyuni, Fatma Sri; Lubis, Mutia Amalia
REAL in Nursing Journal Vol 3, No 1 (2020): REAL in Nursing Journal
Publisher : Universitas Fort De Kock Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/rnj.v3i1.580

Abstract

Background: Job satisfaction is a subjective state based on a comparison of what is actually received by a person from his job compared to what is expected. The study aims to see description of job satisfaction of nurses and to see the relationship between the leadership of the head of the room with the work satisfaction of the implementing nurses in the inpatient room of Batam Hospital. Method: This type of research is analytic descriptive with cross sectional approach. Samples are all nurses in the inpatient room RSBK with a sample of 88 people, with sampling techniques, total sampling. Results: The results of the bivariate chi-square statistical test showed the results of a significant relationship between leadership and the work satisfaction of implementing nurses. Conclusion: Nursing management is expected to always control and conduct training related to nursing leadership (leadership training for the head of the room)
Pengaruh Edukasi Booklet terhadap Kepatuhan Minum Obat pada Pasien Hipertensi Peserta Prolanis di Puskesmas Butang Baru Kabupaten Sarolangun Sari, Trisia Mayang; Sari, Yelly Oktavia; Wahyuni, Fatma Sri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.911

Abstract

Background: Hypertension is a global health problem with a high prevalence and is a significant risk factor for cardiovascular disease. Low medication adherence remains a challenge in the long-term management of hypertension. Health education is a key strategy to improve patients’ understanding and adherence. Booklets are considered a potential educational medium for delivering information in a structured manner. Objective: This study aims to analyse the effect of booklet media education on medication adherence among hypertensive patients participating in the Prolanis program at Butang Baru Public Health Centre, Sarolangun Regency. Methods: This research employed a pretest-posttest control group experimental design. Fifty-six respondents were evenly divided into the intervention group (received booklet-based education) and the control group (received no intervention). Medication adherence was measured using the MARS-5 questionnaire. Data were analysed using the Wilcoxon Signed Ranks test. Results: There was a significant improvement in adherence in the intervention group. The percentage of patients with high adherence increased from 7.14% to 53.57%, while the low adherence category decreased from 25% to 0%. Conversely, the control group showed no meaningful changes. Statistical analysis confirmed these findings, with a p-value = 0.000 (p < 0.05), indicating that the booklet intervention significantly improved adherence. Conclusion: Education through booklet media was proven effective in improving medication adherence among hypertensive patients. Therefore, booklets can be applied as a practical and beneficial intervention strategy to support the success of chronic disease management programs such as Prolanis in primary health care settings.
Pengaruh Edukasi Media Booklet Terhadap Pengetahuan Pasien Diabetes Melitus Tipe 2 Peserta Prolanis Di Puskesmas Lima Kaum I Kabupaten Tanah Datar. Rani, Jihan Shasika; Sari , Yelly Oktavia; Wahyuni, Fatma Sri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.945

Abstract

Background: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion or function. The prevalence of T2DM is increasing globally, including in Indonesia. However, patients’ knowledge regarding disease management remains relatively low. Continuous education is considered an essential strategy to improve disease control.  Objective: This study aimed to analyze the effect of education using booklet media on improving knowledge among T2DM patients enrolled in the Chronic Disease Management Program (Prolanis) at Lima Kaum I Public Health Center, Tanah Datar Regency. Methods: The study employed a pretest-posttest control group design involving a total of 48 respondents, divided into an intervention group (received the booklet) and a control group. The research instrument used was the SDKS INA 1 questionnaire to assess patients’ knowledge. Data were analyzed using the Chi-Square test and the Wilcoxon test. Results: showed a significant increase in patients' knowledge after the educational intervention using the booklet (p=0.000; p<0.05). Conclusion: Therefore, booklet media is proven to be an effective educational tool for enhancing knowledge among patients with Type 2 Diabetes Mellitus.
Time and Concentration-dependent Cytotoxicity of Piperine on Hela Cells Oktavia, Sri; Amir, Arni; Wahyuni, Fatma Sri; Hasmiwati, Hasmiwati
Majalah Kedokteran Andalas Vol. 48 No. 3 (2025): MKA July 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i3.p288-293.2025

Abstract

Piperine, the primary alkaloid of Piper nigrum and Piper longum, is believed to have anticancer properties. Although research on cervical cancer is still in its early stages, piperine's anticancer capabilities have been established in numerous types of cancer and have been shown to target pathways involved in the cell cycle and apoptosis. This study aims to determine how piperine administration time and concentration affect the viability of Hela cells. The MTT method was used to conduct this study. The concentration of piperine utilized was 1,000; 500; 250; 125, and 62.5 µg/mL, and it was administered for 24 and 48 hours. The IC50 values, obtained after incubation for 24 and 48 hours, were 711.21 µg/mL and 419.75 µg/mL, respectively. We may conclude that the viability of HeLa cells is influenced by piperine in a time- and concentration-dependent manner (p<0.05).
Pengaruh Pemberian Salep Fraksi Etil Asetat Daun Meniran (Phyllanthus Ninuri L.) Selama 5 Hari Terhadap Penyembuhan Luka Eksisi pada Tikus Putih Jantan Tobat, Sanubari Rela; Wahyuni, Fatma Sri; Yenny, Satya Wydya; Etriyel, Etriyel; Afrianti, Ria; Rani, Durrotul Nisa
Health and Medical Journal Vol 6, No 1 (2024): HEME January 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v6i1.1481

Abstract

Pendahuluan: Proses penyembuhan luka yang tidak tepat dapat menyebabkan luka menjadi kronis dan meningkatkan resiko infeksi sehingga memperburuk keadaan pasien. Terapi herbal merupakan bagian dari terapi tradisional, selain mudah didapat dan harga terjangkau, terapi herbal memiliki kemampuan menyembuhkan karena bekerja dalam lingkup sel dan molekuler. Tujuan penelitian: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian salep fraksi etil asetat daun meniran terhadap penyembuhan luka eksisi tikus putih jantan. Metode: Pada penelitian ini hewan coba dikelompokkan menjadi 4 kelompok yang terdiri dari 1 kelompok kontrol, 2 kelompok uji dan 1 kelompok pembanding. Kelompok kontrol diberikan basis salep selama 5 hari. Kelompok uji diberikan salep daun meniran fraksi etil asetat konsentrasi 5% dan 10%, dan kelompok pembanding diberikan salep yang beredar yaitu Salep T®. Setiap kelompok diberikan persiapan selama 5 hari. Parameter yang diamati adalah persentase penyembuhan luka dan waktu epitelisasi. Kemudian dilanjutkan uji histopatologi untuk melihat serat kolagen, fibroblas dan re-epitelisasi. Hasil: Hasil uji ANOVA menunjukkan salep daun meniran fraksi etil asetat konsentrasi 10% menunjukkan persentase penyembuhan luka terbaik dengan persentase 33,78% dan waktu epitelisasi terjadi pada hari ke 7. Hasil pemeriksaan histopatologi menunjukkan salep etil asetat fraksi daun meniran 10% hampir mempunyai efek yang sama dengan salep pembanding terhadap proses penyembuhan luka yang ditandai dengan serabut kolagen tampak berdifusi sedang dan tampak menyatu, fibroblas terdiri dari >50 sel dan untuk re-epitelisasi lapisan epidermis mempunyai sudah terbentuk, namun masih ada penebalan. Kesimpulan: Pemberian salep fraksi etil asetat daun meniran (Phyllanthus ninuri L) konsentrasi 5% dapat mempercepat proses penyembuhan luka eksisi tikus putih jantan.
POTENTIAL ANTIVIRAL OF CATECHINS AND THEIR DERIVATIVES TO INHIBIT SARS-COV-2 RECEPTORS OF M pro PROTEIN AND SPIKE GLYCOPROTEIN IN COVID-19 THROUGH THE IN SILICO APPROACH Frengki, Frengki; Putra, Deddi Prima; Wahyuni, Fatma Sri; Khambri, Daan; Vanda, Henni; Sofia, Vivi
Jurnal Kedokteran Hewan Vol 14, No 3 (2020): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i3.16652

Abstract

Catechin and their derivatives have been studied to have antiviral potential against COVID-19 through in silico method pharmacokinetics screening and molecular docking. Pharmacokinetics and toxicity profiles were obtained through the ADMETSAR server and SwissADME server. Then proceed with the prediction of affinity through the method molecular docking using the software application MOE 2007.09. The testmaterial is in the form of a 3D catechin structure and its derivatives as well as several control ligands downloaded via Pubmed. While templatethe Receptor M pro protein and the Spike glycoprotein are downloaded from pdb.org (PDB ID: 6LU7 and 6LXT). The pharmacokinetic profile of catechins is relatively better than all control ligands with the lowest toxicity. Molecular docking results also show that catechins and theirderivatives have a stronger affinity than control ligands. This research proves that catechin has antiviral potential through inhibition of Mpro protein and Spike glycoprotein COVID-19 virus.
Co-Authors . Almahdy AA Sudharmawan, AA Aan Ardiansyah Adinny Julmiza Adriani Susanty Afrina, Uci Alimin, Nur Almahdy A Almahdy Almahdy Almahdy, . Amir, Arni Annisa Annisa Ardiansyah, Aan Arni Amir Astari, Lita Tri astri doris Aziz, Enda Desriansyah Benardo Benardo Benardo, Benardo Berna Elya Daan Khambri Dachriyanus Deddi Prima Deddi Prima Putra Dedi Prima Putra Dessy Arisanti Dewi, Citra Kartika Dian Ayu Juwita Dian Sanita Putri Diana Laila Ramatillah Dira Dira Dira Hefni Dwi Afrianti, Rezy Dwisari Dillasamola Elidahanum Husni Enda Desriansyah Aziz Erizal Erizal Etriyel Myh Etriyel, Etriyel Febria, Nurma Fendri, Sandra Tri Juli Fithri Yani Fithriyani Fithriyani Fitriyani Siregar Frengki Frengki Frengki Frengki, Frengki Fridelly Mairani Apt Gloria, Fransisca Haiyul Fadhli Hansen Nasif Harmawati harmawati Hasmiwati Henni Vanda Henni Vanda Henni Vanda Henni Vanda Henny Vanda Ihsan Ikhtiarudin Ikhwan Resmala Sudji Intan Nedia Putri Jamilah Abbas Julmiza, Adinny Khairil Armal Lubis, Mutia Amalia Lukas, Stefanus Lusianti, Mittha Lusianti, Mittha Magdazaleni, Magdazaleni Mai Efdi Mawarti, Indah Meri Susanti Michael Michael Miming Andika Mira Febrina Mudinillah, Adam Nilda Lely Noni Zakiah Nurdina Putri Oktavia, Sri Paulina, Ida Pedro Anugrah Aswan Putra, Deddy Prima Putra, Deddy Prima Putri, Zifriyanthi Minanda Putri, Zifriyanthi Minanda Rachmaini, Fitri Rahmad Abdillah Rahmad Abdillah Ramatillah, Diana Laila Rani, Durrotul Nisa Rani, Jihan Shasika Ria Afrianti Rika Sepriani Rizki Amaliyah Amaliyah Rizqa Hasanah Salman - Sandra Hardini Sari , Yelly Oktavia Sari, Trisia Mayang Sari, Yelly Oktavia Satya Wydya Yenny Sekar, Andisyah Putri Sinata, Novia Sofia, Sri Esky Srangenge, Yoneta Sri Oktavia Suci Sutma Surya Dharma Suryati Suryati Suryati Tobat, Sanubari Rela Trisnawati, Nina Trisnawati, Nina Vetty Priscilla Vivi Sofia Vivi Sofia Vivi Sofia Wahyudi, Agung Aji Wardi, Epi Supri Wawan Wahyudi wessi windrasari Witha, Nikenly Fajar Yanwirasti Yanwirasti Yanwirasti Yanwirasti Yelly Oktavia Sari Yohannes Alen Yoneta Srangenge Yufi Aldi Yufri Aldi Yulia, Revi