Article Per Year (5 Year)
p-Index From 2021 - 2026
4.462
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan JURNAL KIMIA SAINS DAN APLIKASI Pharmaciana: Jurnal Kefarmasian Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Jurnal Fitofarmaka Indonesia Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Kesehatan Medika Saintika JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun JFIOnline Majalah Kedokteran Andalas Health and Medical Journal Real in Nursing Journal JPK: Jurnal Proteksi Kesehatan Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmaceutical Sciences and Research (PSR) Jurnal Kedokteran Hewan Jurnal Farmasi Indonesia Journal of Pharmaceutical and Sciences. Jurnal Riset Multidisiplin dan Inovasi Teknologi PEDAMAS (Pengabdian Kepada Masyarakat) Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Akademika Baiturrahim Jambi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan NERS Jurnal Keperawatan
Fatma Sri Wahyuni
Fakultas Farmasi, Universitas Andalas, Kampus Limau Manis, Padang, Sumatera Barat, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 56 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 56 Documents
Search

 2   3   4   5   6 
Evaluasi Hasil Klinis Pada Tim Medis yang Mendapat Vaksinasi Booster di Rumah Sakit Bengkayang Kalimantan Barat Lukas, Stefanus; Ramatillah, Diana Laila; Aldi, Yufri; Wahyuni, Fatma Sri; Paulina, Ida; Gloria, Fransisca; Michael, Michael
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 14 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.685 KB) | DOI: 10.35617/jfionline.v14i2.70

Abstract

Abstract: In reducing the risk of transmission to health workers, the Government has given the 3rd Booster Covid-19 Vaccination since August 2021. This study uses the Astra Zeneca Vaccine, Moderna Vaccine and Pfizer Vaccine. The purpose of this study was to evaluate the effectiveness of the 3rd Booster vaccine and the clinical outcomes of post-vaccination health workers at West Kalimantan Hospital. Research method Observational Cross-sectional Prospective by conducting questionnaires and interviewing health workers. Samples were taken by convenience sampling and statistical analysis of chis-square. The research instrument used a questionnaire distributed in the hospital. In the study, it was found that as many as 12.60% (14 out of 118 health workers) were infected with Covid-19. The habit that influenced the effectiveness of the 3rd booster vaccination was sunbathing (p <0.05). The low severity of health workers infected with Covid-19 after the 3rd booster vaccine can be seen from the place of treatment, namely 97% independent isolation, 60% without using antivirals and 77% without using antibiotics. The type of vitamin that is most widely used is vitamin C. Hence with this booster vaccination aims to prevent and reduce the severity of patients who contract Covid-19 after vaccination.
Kepemimpinan Kepala Ruangan dan Kepuasan Kerja Perawat Pelaksana Yulia, Revi; Wahyuni, Fatma Sri; Lubis, Mutia Amalia
REAL in Nursing Journal Vol 3, No 1 (2020): REAL in Nursing Journal
Publisher : Universitas Fort De Kock Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/rnj.v3i1.580

Abstract

Background: Job satisfaction is a subjective state based on a comparison of what is actually received by a person from his job compared to what is expected. The study aims to see description of job satisfaction of nurses and to see the relationship between the leadership of the head of the room with the work satisfaction of the implementing nurses in the inpatient room of Batam Hospital. Method: This type of research is analytic descriptive with cross sectional approach. Samples are all nurses in the inpatient room RSBK with a sample of 88 people, with sampling techniques, total sampling. Results: The results of the bivariate chi-square statistical test showed the results of a significant relationship between leadership and the work satisfaction of implementing nurses. Conclusion: Nursing management is expected to always control and conduct training related to nursing leadership (leadership training for the head of the room)
Pengaruh Edukasi Booklet terhadap Kepatuhan Minum Obat pada Pasien Hipertensi Peserta Prolanis di Puskesmas Butang Baru Kabupaten Sarolangun Sari, Trisia Mayang; Sari, Yelly Oktavia; Wahyuni, Fatma Sri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.911

Abstract

Background: Hypertension is a global health problem with a high prevalence and is a significant risk factor for cardiovascular disease. Low medication adherence remains a challenge in the long-term management of hypertension. Health education is a key strategy to improve patients’ understanding and adherence. Booklets are considered a potential educational medium for delivering information in a structured manner. Objective: This study aims to analyse the effect of booklet media education on medication adherence among hypertensive patients participating in the Prolanis program at Butang Baru Public Health Centre, Sarolangun Regency. Methods: This research employed a pretest-posttest control group experimental design. Fifty-six respondents were evenly divided into the intervention group (received booklet-based education) and the control group (received no intervention). Medication adherence was measured using the MARS-5 questionnaire. Data were analysed using the Wilcoxon Signed Ranks test. Results: There was a significant improvement in adherence in the intervention group. The percentage of patients with high adherence increased from 7.14% to 53.57%, while the low adherence category decreased from 25% to 0%. Conversely, the control group showed no meaningful changes. Statistical analysis confirmed these findings, with a p-value = 0.000 (p < 0.05), indicating that the booklet intervention significantly improved adherence. Conclusion: Education through booklet media was proven effective in improving medication adherence among hypertensive patients. Therefore, booklets can be applied as a practical and beneficial intervention strategy to support the success of chronic disease management programs such as Prolanis in primary health care settings.
Pengaruh Edukasi Media Booklet Terhadap Pengetahuan Pasien Diabetes Melitus Tipe 2 Peserta Prolanis Di Puskesmas Lima Kaum I Kabupaten Tanah Datar. Rani, Jihan Shasika; Sari , Yelly Oktavia; Wahyuni, Fatma Sri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.945

Abstract

Background: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion or function. The prevalence of T2DM is increasing globally, including in Indonesia. However, patients’ knowledge regarding disease management remains relatively low. Continuous education is considered an essential strategy to improve disease control.  Objective: This study aimed to analyze the effect of education using booklet media on improving knowledge among T2DM patients enrolled in the Chronic Disease Management Program (Prolanis) at Lima Kaum I Public Health Center, Tanah Datar Regency. Methods: The study employed a pretest-posttest control group design involving a total of 48 respondents, divided into an intervention group (received the booklet) and a control group. The research instrument used was the SDKS INA 1 questionnaire to assess patients’ knowledge. Data were analyzed using the Chi-Square test and the Wilcoxon test. Results: showed a significant increase in patients' knowledge after the educational intervention using the booklet (p=0.000; p<0.05). Conclusion: Therefore, booklet media is proven to be an effective educational tool for enhancing knowledge among patients with Type 2 Diabetes Mellitus.
Time and Concentration-dependent Cytotoxicity of Piperine on Hela Cells Oktavia, Sri; Amir, Arni; Wahyuni, Fatma Sri; Hasmiwati, Hasmiwati
Majalah Kedokteran Andalas Vol. 48 No. 3 (2025): MKA July 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i3.p288-293.2025

Abstract

Piperine, the primary alkaloid of Piper nigrum and Piper longum, is believed to have anticancer properties. Although research on cervical cancer is still in its early stages, piperine's anticancer capabilities have been established in numerous types of cancer and have been shown to target pathways involved in the cell cycle and apoptosis. This study aims to determine how piperine administration time and concentration affect the viability of Hela cells. The MTT method was used to conduct this study. The concentration of piperine utilized was 1,000; 500; 250; 125, and 62.5 µg/mL, and it was administered for 24 and 48 hours. The IC50 values, obtained after incubation for 24 and 48 hours, were 711.21 µg/mL and 419.75 µg/mL, respectively. We may conclude that the viability of HeLa cells is influenced by piperine in a time- and concentration-dependent manner (p<0.05).
Pengaruh Pemberian Salep Fraksi Etil Asetat Daun Meniran (Phyllanthus Ninuri L.) Selama 5 Hari Terhadap Penyembuhan Luka Eksisi pada Tikus Putih Jantan Tobat, Sanubari Rela; Wahyuni, Fatma Sri; Yenny, Satya Wydya; Etriyel, Etriyel; Afrianti, Ria; Rani, Durrotul Nisa
Health and Medical Journal Vol 6, No 1 (2024): HEME January 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v6i1.1481

Abstract

Pendahuluan: Proses penyembuhan luka yang tidak tepat dapat menyebabkan luka menjadi kronis dan meningkatkan resiko infeksi sehingga memperburuk keadaan pasien. Terapi herbal merupakan bagian dari terapi tradisional, selain mudah didapat dan harga terjangkau, terapi herbal memiliki kemampuan menyembuhkan karena bekerja dalam lingkup sel dan molekuler. Tujuan penelitian: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian salep fraksi etil asetat daun meniran terhadap penyembuhan luka eksisi tikus putih jantan. Metode: Pada penelitian ini hewan coba dikelompokkan menjadi 4 kelompok yang terdiri dari 1 kelompok kontrol, 2 kelompok uji dan 1 kelompok pembanding. Kelompok kontrol diberikan basis salep selama 5 hari. Kelompok uji diberikan salep daun meniran fraksi etil asetat konsentrasi 5% dan 10%, dan kelompok pembanding diberikan salep yang beredar yaitu Salep T®. Setiap kelompok diberikan persiapan selama 5 hari. Parameter yang diamati adalah persentase penyembuhan luka dan waktu epitelisasi. Kemudian dilanjutkan uji histopatologi untuk melihat serat kolagen, fibroblas dan re-epitelisasi. Hasil: Hasil uji ANOVA menunjukkan salep daun meniran fraksi etil asetat konsentrasi 10% menunjukkan persentase penyembuhan luka terbaik dengan persentase 33,78% dan waktu epitelisasi terjadi pada hari ke 7. Hasil pemeriksaan histopatologi menunjukkan salep etil asetat fraksi daun meniran 10% hampir mempunyai efek yang sama dengan salep pembanding terhadap proses penyembuhan luka yang ditandai dengan serabut kolagen tampak berdifusi sedang dan tampak menyatu, fibroblas terdiri dari >50 sel dan untuk re-epitelisasi lapisan epidermis mempunyai sudah terbentuk, namun masih ada penebalan. Kesimpulan: Pemberian salep fraksi etil asetat daun meniran (Phyllanthus ninuri L) konsentrasi 5% dapat mempercepat proses penyembuhan luka eksisi tikus putih jantan.
POTENTIAL ANTIVIRAL OF CATECHINS AND THEIR DERIVATIVES TO INHIBIT SARS-COV-2 RECEPTORS OF M pro PROTEIN AND SPIKE GLYCOPROTEIN IN COVID-19 THROUGH THE IN SILICO APPROACH Frengki, Frengki; Putra, Deddi Prima; Wahyuni, Fatma Sri; Khambri, Daan; Vanda, Henni; Sofia, Vivi
Jurnal Kedokteran Hewan Vol 14, No 3 (2020): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i3.16652

Abstract

Catechin and their derivatives have been studied to have antiviral potential against COVID-19 through in silico method pharmacokinetics screening and molecular docking. Pharmacokinetics and toxicity profiles were obtained through the ADMETSAR server and SwissADME server. Then proceed with the prediction of affinity through the method molecular docking using the software application MOE 2007.09. The testmaterial is in the form of a 3D catechin structure and its derivatives as well as several control ligands downloaded via Pubmed. While templatethe Receptor M pro protein and the Spike glycoprotein are downloaded from pdb.org (PDB ID: 6LU7 and 6LXT). The pharmacokinetic profile of catechins is relatively better than all control ligands with the lowest toxicity. Molecular docking results also show that catechins and theirderivatives have a stronger affinity than control ligands. This research proves that catechin has antiviral potential through inhibition of Mpro protein and Spike glycoprotein COVID-19 virus.
EDUKASI PENYULUHAN OBAT DAN PENGOBATAN GRATIS BAGI MASYARAKAT DI DESA PERKAMPUNGAN ADAT SIJUNJUNG Dwisari Dillasamola; Yoneta Srangenge; Aan Ardiansyah; Yufri Aldi; Fatma Sri Wahyuni; Elidahanum Husni; Rahmad Abdillah; Adinny Julmiza; Benardo Benardo
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 2 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i2.600

Abstract

Community health education is crucial, including education on the rational use of antibiotics, as well as halal food and medicine. Additionally, providing free medical treatment has a significant impact, encouraging the community to prioritize health and maintain it as a primary concern. This community service project was conducted in the Desa Perkampungan Adat Sijunjung. The objective of this activity is to maintain and improve the community's health status. One way to achieve this is through community service activities. The service involved educational sessions on medicines and health, as well as free medical treatment, in collaboration with the Faculty of Pharmacy and the Faculty of Medicine at Universitas Andalas. The education targeted pregnant women and the elderly, focusing on proper medication selection, rational use of antibiotics, and education on halal medicines and food. Free medical treatment involved specialist doctors and pharmacists, who also provided counseling on medications to patients. The results of the activity showed high community enthusiasm, with more than 100 prescriptions filled. The education on the rational use of medications, particularly antibiotics, is expected to increase community awareness and knowledge. This activity also highlights the importance of pharmacists in providing patient-oriented pharmaceutical services, as well as the importance of promotional and preventive efforts in maintaining public health. It can be concluded that free medical treatment is expected to encourage the community to be more health-conscious and less fearful of seeking medical care.
PENGARUH PAPARAN ASAP OBAT NYAMUK BAKAR TERHADAP KADAR ESTROGEN DAN KUALITAS SPERMATOZOA PADA MENCIT (Mus musculus) Eka Desnita; Almahdy Almahdy; Yufri Aldi; Fatma Sri Wahyuni; Dachriyanus; Rama Feriska Putra
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 12 No. 1 (2026): Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v12i1.989

Abstract

Penggunaan obat nyamuk bakar berbahan aktif piretroid masih luas di lingkungan rumah tangga dan berpotensi menimbulkan dampak terhadap sistem reproduksi akibat paparan asap hasil pembakaran. Penelitian ini bertujuan untuk menganalisis pengaruh paparan asap obat nyamuk bakar terhadap kualitas spermatozoa dan kadar estrogen serum. Penelitian eksperimental dilakukan pada Mus musculus yang dibagi menjadi kelompok kontrol dan kelompok paparan. Parameter yang diamati meliputi konsentrasi spermatozoa, morfologi spermatozoa, dan kadar estrogen serum, kemudian dianalisis secara statistik untuk menentukan perbedaan antar kelompok. Hasil penelitian menunjukkan bahwa paparan asap obat nyamuk bakar secara signifikan menurunkan konsentrasi spermatozoa dan meningkatkan persentase morfologi abnormal dibandingkan kelompok kontrol (p < 0,05). Kadar estrogen serum pada kelompok paparan menunjukkan kecenderungan menurun, namun tidak berbeda signifikan secara statistik (p > 0,05). Disimpulkan bahwa paparan asap obat nyamuk bakar berbasis piretroid berpotensi menurunkan kualitas spermatozoa dan memengaruhi regulasi hormonal. Temuan ini mengindikasikan adanya risiko gangguan fungsi reproduksi akibat paparan insektisida rumah tangga secara kronis.
The Effect of miR-10b Mimic Transfection on Invasion and Proliferation Gene Expression as the Direct Target of the miR-10b Pathway in T47D Breast Cancer Cell Lines Dessy Arisanty; Zolkapli Eshak; Fatma Sri Wahyuni; Afifatul Achyar; Salsabila Putri Khairani
Jurnal Kimia Sains dan Aplikasi Vol 29, No 1 (2026): Volume 29 Issue 1 Year 2026
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.29.1.58-63

Abstract

Breast cancer remains one of the leading causes of death in women worldwide, with high incidence and mortality rates. The abnormal expression of the small non-coding RNA, microRNA-10b (miR-10b), has been associated with breast cancer progression. miR-10b is involved in various biological processes, including proliferation, metastasis, and drug resistance. However, the underlying mechanism by which miR-10b contributes to breast cancer progression remains unclear. This study aimed to investigate the effect of miR-10b on the expression of HOXD10 and PI3K genes, as well as its impact on cell viability and proliferation in breast cancer cells. In this study, T47D breast cancer cells were transfected with mimic miR-10b using the FANA-oligo transfection method at concentrations of 1, 2.5, and 5 µM. Cell viability was assessed using the MTT assay, while HOXD10 and PI3K gene expression levels were measured using RT-qPCR and ELISA. Data were analysed using paired t-tests with SPSS, and results were considered statistically significant at p < 0.05. The results showed that mimic miR-10b induced a dose-dependent increase in cell proliferation. Notably, only HOXD10 gene expression was significantly affected by the transfection, while PI3K gene expression remained unchanged. Cells transfected with 5 µM miR-10b mimic exhibited the highest proliferation rate compared to non-transfected controls (p < 0.05). In conclusion, miR-10b promotes breast cancer cell proliferation by downregulating HOXD10 expression, independent of PI3K, suggesting it is a potential target for further investigation.
Co-Authors . Almahdy AA Sudharmawan, AA Aan Ardiansyah Aan Ardiansyah Abdillah, Rahmad Adinny Julmiza Adinny Julmiza Adriani Susanty Afifatul Achyar Afrina, Uci Alimin, Nur Almahdy A Almahdy Almahdy Almahdy Almahdy Almahdy, . Amir, Arni Annisa Annisa Arni Amir Astari, Lita Tri astri doris Astri Doris Aziz, Enda Desriansyah Benardo Benardo Benardo Benardo Berna Elya Cindy Elvionita Daan Khambri Dachriyanus Deddi Prima Deddi Prima Putra Dedi Prima Putra Dessy Arisanti Dessy Arisanty Dewi, Citra Kartika Dian Ayu Juwita Dian Ayu Juwita Dian Sanita Putri Diana Laila Ramatillah Dira Dira Dira Hefni Dwi Afrianti, Rezy Dwisari Dillasamola Eka Desnita Elidahanum Husni Enda Desriansyah Aziz Erizal Zaini Etriyel Myh Etriyel, Etriyel Fatiyah Nurazizah Febria, Nurma Fendri, Sandra Tri Juli Fithri Yani Fithriyani Fithriyani Fitriyani Siregar Frengki Frengki Frengki Frengki, Frengki Fridelly Mairani Apt Gloria, Fransisca Haiyul Fadhli Hansen Nasif Harmawati harmawati Hasmiwati Henni Vanda Henni Vanda Henni Vanda Henni Vanda Henny Vanda Ihsan Ikhtiarudin Ikhwan Resmala Sudji Intan Nedia Putri Jamilah Abbas Khairil Armal Lubis, Mutia Amalia Lukas, Stefanus Lusianti, Mittha Lusianti, Mittha Magdazaleni, Magdazaleni Mai Efdi Mawarti, Indah Mega Fatimah Rosana Meri Susanti Michael Michael Miming Andika Mira Febrina Mudinillah, Adam Nilda Lely Noni Zakiah Nurdina Putri Oktavia, Sri Paulina, Ida Pedro Anugrah Aswan Purnawan Pontana Putra Putra, Deddy Prima Putra, Deddy Prima Putri, Zifriyanthi Minanda Putri, Zifriyanthi Minanda Rachmaini, Fitri Rama Feriska Putra Ramatillah, Diana Laila Rani, Durrotul Nisa Rani, Jihan Shasika Ria Afrianti Rika Sepriani Rizki Amaliyah Amaliyah Rizqa Hasanah Salman - Salsabila Putri Khairani Sandra Hardini Sari , Yelly Oktavia Sari, Trisia Mayang Sari, Yelly Oktavia Satya Wydya Yenny Sekar, Andisyah Putri Sinata, Novia Siska Ferilda Sofia, Sri Esky Sri Oktavia Suci Sutma Surya Dharma Suryati Suryati Suryati Syofyan Syofyan Tessa Amanda Primadhini Tobat, Sanubari Rela Trisnawati, Nina Trisnawati, Nina Vetty Priscilla Vivi Sofia Wahyudi, Agung Aji Wardi, Epi Supri Wawan Wahyudi wessi windrasari Wida Ningsih Witha, Nikenly Fajar Yanwirasti Yanwirasti Yanwirasti Yanwirasti Yelly Oktavia Sari Yelly Oktavia Sari Yohannes Alen Yoneta Srangenge Yoneta Srangenge Yufi Aldi Yufri Aldi Yulia, Revi Zolkapli Eshak