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All Journal Jurnal Manajemen Terapan dan Keuangan Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences JURNAL GIZI INDONESIA Jurnal Manajemen Bisnis Fokus Bisnis Proceeding Seminar LPPM UMP Tahun 2014 INDONESIAN JOURNAL OF PHARMACY DERIVATIF Jurnal Akuntansi dan Pajak Jurnal Maneksi (Management Ekonomi Dan Akuntansi) As-syifaa Jurnal Farmasi JURNAL MANAJEMEN MOTIVASI Jurnal SOLMA ANNALES BOGORIENSES RJABM (Research Journal of Accounting and Business Management) Muhammadiyah International Journal of Economics and Business SENTRALISASI International Journal of Islamic Business and Economics (IJIBEC) Jurnal Ilmu Manajemen Jurnal Mantik BALANCE Jurnal Akuntansi dan Bisnis International Journal of Economics, Business and Accounting Research (IJEBAR) Jurnal Ilmiah Edunomika (JIE) Budimas : Jurnal Pengabdian Masyarakat Entrepreneurship Bisnis Manajemen Akuntansi (E-BISMA) Jurnal Ekonomi dan Bisnis Digital (MINISTAL) East Asian Journal of Multidisciplinary Research (EAJMR) Makara Journal of Science SEAQIS Journal of Science Education Asian Journal of Management Analytics Prosiding University Research Colloquium International Journal of Business and Applied Economics (IJBAE) e-Jurnal Apresiasi Ekonomi IIJSE Fokus Bisnis: Media Pengkajian Manajemen dan Akuntansi Riset Akuntansi dan Keuangan Indonesia International Journal of Economics, Business and Innovation Research JIPITI: Jurnal Pengabdian kepada Masyarakat JURNAL MANAJEMEN DAN BISNIS INDONESIA Annales Bogorienses Berita Biologi BISNIS : Jurnal Bisnis dan Manajemen Islam
Akhmad Darmawan
Department of Chemistry University of Indonesia Kampus Depok, Jl. Margonda Raya, Depok, West Java, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Physics Social Sciences Other

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PENGARUH KONFLIK KERJA, KELELAHAN KERJA DAN BEBAN KERJA TERHADAP KINERJA KARYAWAN PT USAHA KARYA CILACAP Dewi, Sandra; Darmawan, Akhmad; Muji R., Tri Septin; Haryanto, Totok
Jurnal Akuntansi dan Pajak Vol. 24 No. 2 (2024): JAP : Vol. 24, No. 2, Agustus 2023 - Januari 2024
Publisher : ITB AAS INDONESIA

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Abstract

The aim of this research is to determine the effect of work conflict, work fatigue and workload on employee performance. This type of research is quantitative survey research. The population of this study was 120 employees and the sample size was 107. The sampling technique used was nonprobability sampling with a sample method, namely purposive sampling. The analysis test used multiple regression using SPSS version 20 for Windows software. The research results show that work conflict has a negative and significant effect on employee performance. Work fatigue has a negative and insignificant effect on employee performance. Workload has a negative and significant effect on employee performance
PENGARUH KEPEMIMPINAN TRANSFORMASIONAL, MOTIVASI, PELATIHAN KERJA DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN PADA PERUSAHAAN DAERAH AIR MINUM (PDAM) TIRTA SATRIA KABUPATEN BANYUMAS Putra, Nafis Mahesa; Darmawan, Akhmad; Suyoto, Suyoto; Haryanto, Totok
Jurnal Akuntansi dan Pajak Vol. 24 No. 2 (2024): JAP : Vol. 24, No. 2, Agustus 2023 - Januari 2024
Publisher : ITB AAS INDONESIA

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Abstract

This research aims to determine the influence of transformational leadership, motivation, training and work environment on employee performance at Perumdam Tirta Satria, Banyumas Regency. The population in this study was all employees at Perumdam Tirta Satria, Banyumas Regency, totaling 133 employees. The sampling technique uses purposive sampling with criteria namely general, financial and mechanical division employees, who have worked for more than one year, excluding leaders. The sample size in this study was 100 samples using the Slovin formula. Analysis uses multiple linear regression and correlation using SPSS version 26. The results of the research show that transformational leadership and motivation have a positive and significant effect on employee performance, training has an insignificant positive effect, while the work environment does not have a significant effect on employee performance. Keyword: transformational leadership, motivation, job training, work environment, and employee perfomance
Cytotoxic Activity of Flavonoid Compounds Isolated from Tetrameles Nudliflora Leaves Megawati, Megawati; Darmawan, Akhmad; Fajriah, Sofa
Annales Bogorienses Vol. 23 No. 2 (2019): Annales Bogorienses
Publisher : BRIN

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Abstract

Tetrameles nudliflora is one of the endemic plants in Wallace region, especially in Mekongga Forest, Southeast Sulawesi, Indonesia. As part of our project in the field of natural drug discovery based on local bioresources, this study aimed to isolate secondary metabolite compounds from the ethyl acetate fractions of the leaves of T. nudiflora and evaluate their cytotoxic activities against breast carcinoma cancer lines, MCF-7. The methods used were various chromatography techniques such as vacuum column chromatography, gravitation column chromatography, thin layer chromatography, preparative thin layer chromatography, and re-crystallization using two different organic solvents. In the present study, two flavonoid compounds, kaempferol (1) and quercetin (2) were identified. The structures of 1-2 were determined using serial spectroscopic techniques, including mass spectrometry, one- and two-dimensional nuclear magnetic resonance. Moreover, using 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide (MTT) assay method, both compounds showed in vitro cytotoxic activity IC50 of 34.162 and 133.148 μg mL-1, respectively against MCF-7 cell lines.
Identification of a New Compound as α-Glucosidase Inhibitor from Aspergillus aculeatus Dewi, Rizna Triana; Suparman, Asep; Mulyani, Hanny; Darmawan, Akhmad; Lotulung, Puspa Dewi N.
Annales Bogorienses Vol. 20 No. 1 (2016): Annales Bogorienses
Publisher : BRIN

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Abstract

Terestrial fungi are of great importance as potential sources of pharmaceutical agent. Aspergillus aculeatus, a fungus isolated from soil sample collected in Indonesia, was cultured in liquid media to investigate a novel compound as inhibitor -glucosidase. The mycelium extract of A. aculeatus shows potential activity against Saccharomyces cereviseae -glucosidase and mild activity against mammalian -glucosidase with IC50 values of 9.57 μg/mL and 470.76 mg/mL, respectively. Enzyme assay-guided fractionation of this extract afforded rubrofusarin (1). Rubrofusarin, a linear naphtho--pyrone, is a natural pigment from Aspergillus sp. Interestingly, compound 1 shows potential inhibitory activity against mammalian -glucosidase (IC50 of 92.7 μg/mL), but no to S. cereviseae -glucosidase. The results suggest that A. aculeatus is a promising natural source as a lead compound in the discovery of antidiabetic drug.
ISOLATION AND IDENTIFICATION OF APIGENIN, A FLAVONOID COMPOUND FROM MACARANGA HYPOLEUCA (REICHB.F. & ZOLL.) Aisya, Sitti; Megawati, Megawati; Ariani, Novita; Sukirno, Sukirno; Minarti, Minarti; Kurniawan, Hendris Hendarsyah; Hidayat, Arief; Hendra, Medi; Primahana, Gian; Darmawan, Akhmad
Berita Biologi Vol 23 No 1 (2024): Berita Biologi
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/beritabiologi.2024.3242

Abstract

The study on Macarang hypolueca (Reichb.f. & Zoll.), which was collected from secondary forests around Samarinda City, East Kalimantan, involved phytochemical investigations that led to the isolation of a flavone type compound of flavonoid from the ethyl acetate fraction. To separate the compounds, silica gel column chromatography was utilized with a gradient solvent system of n-hexane and ethyl acetate, along with the addition of 5%. Infrared analysis (FTIR), mass spectrum (LC-ESI-MS), and nuclear magnetic resonance (1D- and 2D-NMR) were used to identify and elucidate the structure. Based on spectroscopic data and comparison with appropriate references, the isolated compound was identified as apigenin
Investigating Critical Thinking Skills in Rural Middle School Students through STEM Education: A Qualitative Case Study from Sumedang hajar, maya umi; Nurmalasari, Santy; Darmawan, Akhmad
SEAQIS Journal of Science Education Vol. 5 No. 02 (2025): SEAQIS Journal of Science Education
Publisher : SEAMEO QITEP in Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58249/sjse.v5i02.200

Abstract

Learning plays a crucial role in fostering students’ critical thinking skills, enabling them to address the challenges they face in their daily lives. This study was conducted in Sumedang, West Java, where students experience limited water availability. The main water sources are located far from residential areas, requiring students to make long trips each morning to fetch water from a distant river. This qualitative descriptive study aimed to explore how students employ critical thinking skills while engaging in contextual STEM learning through the development of a non-electric water pump project. The project involved seventh-grade students participating in science classes using a contextual STEM approach over one semester. Data were collected and analysed through observation, document analysis, and audio and video recordings using Transcript-Based Lesson Analysis. Indicators of critical thinking such as questioning, articulating assumptions, and demonstrating open-mindedness were observed during the STEM learning process of designing the non-electric water pump. The emergence of these skills varied across learning phases, individual characteristics, and group dynamics. Contextual STEM learning not only promotes critical thinking but also equips students with essential life skills for global competition in the 21st century by preparing them to solve real-world problems. The findings of this study provide insights for educators in designing more meaningful science learning experiences in the future.
Peningkatan Kualitas Produk Keripik Kentang pada Industri Rumah Tangga (IRT) Tooop Rasa, Sokaraja, Kabupaten Banyumas Melalui Pelatihan CPPOB dan Bahan Pangan Halal Mulia, Dini Siswani; Wati, Ratna Kartika; Suwarsito, Suwarsito; Wahyuni, Sri; Darmawan, Akhmad; Susylowati, Dewi; Saputra, Eqwar
Jurnal SOLMA Vol. 14 No. 3 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i3.17181

Abstract

Background: Industri Rumah Tangga (IRT) Tooop Rasa merupakan IRT yang memiliki berbagai usaha produksi olahan pangan, salah satunya adalah keripik kentang. Produk ini termasuk produk unggulan dengan bahan baku yang melimpah dan kontinu. Namun, pembuatan keripik kentang belum mengaplikasikan prinsip Cara Produksi Pangan Olahan yang Baik (CPPOB) dan produk belum bersertifikat halal. Kegiatan pembinaan IRT ini bertujuan untuk memberikan edukasi atau pelatihan CPPOB dan bahan pangan halal agar produk berkualitas baik dan dapat meningkatkan daya saing. Metode: Kegiatan pengabdian dilakukan dengan metode pendekatan partisipatoris dengan tahap kegiatan meliputi sosialisasi, pelatihan, pendampingan, dan evaluasi. Tingkat keberhasilan program diukur dengan metode one group pre-test and post-test. Hasil: Hasil kegiatan menunjukkan 87,50% anggota mitra memahami dan mampu mengimplementasikan CPPOB, dan 85,00% anggota mitra memahami dan mampu mengimplementasikan tentang bahan pangan halal. Produk keripik kentang telah didampingi dalam pengajuan sertifikasi halal. Kesimpulan: Kegiatan pengabdian telah berhasil memberikan edukasi atau pelatihan CPPOB dan bahan pangan halal yang berimplikasi positif terhadap peningkatan pemahaman dan keterampilan mitra. Produk keripik kentang yang dihasilkan berkualitas baik dan memenuhi kriteria sesuai SNI 4031:2018, yaitu bau, rasa, tekstur, dan penampakan normal, salah satunya ditandai dengan warna kuning merata dan tekstur renyah. Selain itu, mitra telah berhasil mendapatkan sertifikat halal sehingga dapat meningkatkan daya saing.
PERAN JOB EMBEDDEDNESS DALAM MEMEDIASI PENGARUH LINGKUNGAN KERJA DAN KOMPENSASI TERHADAP RETENSI KARYAWAN: STUDI PADA INDUSTRI KULINER Alfandi, Asha; Darmawan, Akhmad; Suyoto, Suyoto; Haryanto, Totok
Jurnal Manajemen Terapan dan Keuangan Vol. 14 No. 04 (2025): Jurnal Manajemen Terapan dan Keuangan
Publisher : Program Studi Manajemen Pemerintahan dan Keuangan Daerah Fakultas Ekonomi dan Bisnis Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmk.v14i04.52226

Abstract

Penelitian ini mengkaji peran mediasi job embeddedness dalam hubungan antara lingkungan kerja, kompensasi, dan retensi karyawan di sektor kuliner Kota Purwokerto, Indonesia. Berlandaskan Social Exchange Theory, penelitian kuantitatif dilakukan melalui survei terhadap karyawan dari delapan perusahaan. Data dianalisis menggunakan Partial Least Squares Structural Equation Modeling (PLS-SEM). Hasil penelitian menunjukkan bahwa lingkungan kerja berpengaruh positif dan signifikan terhadap retensi, sedangkan kompensasi tidak memiliki pengaruh langsung yang signifikan. Analisis jalur mengonfirmasi bahwa job embeddedness secara penuh dan signifikan memediasi pengaruh kedua variabel prediktor tersebut dan juga memberikan pengaruh langsung yang kuat dan positif terhadap retensi. Model penelitian ini menunjukkan relevansi prediktif dan daya penjelas yang kuat. Temuan ini juga menegaskan bahwa strategi retensi yang efektif perlu berfokus pada penguatan job embeddedness, bukan semata-mata pada kompensasi finansial.
Analysis of the Mediating Role of OCB in the Relationship Between LOC, Self-Efficacy, and Organizational Justice on Employee Performance Nursanti, Tia; Darmawan, Akhmad; Arofah, Rifka Utami; Suyoto, Suyoto; Haryanto, Totok
Indonesian Interdisciplinary Journal of Sharia Economics (IIJSE) Vol 9 No 1 (2026): Sharia Economics
Publisher : Universitas KH. Abdul Chalim Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31538/iijse.v9i1.9482

Abstract

This study aims to analyze the effect of LOC, self-efficacy, and organizational justice on employee performance with OCB as a mediating variable among employees in the cutting department of PT. Hyup Sung Indonesia. This study uses quantitative research with saturated sampling or census method. The population consists of 132 employees in the cutting department. Data were collected using direct questionnaires. Data analysis used SEM-PLS. The results show that LOC does not significantly affect employee performance, but has a positive and significant effect on OCB. Self-efficacy and organizational justice positively and significantly affect employee performance and OCB. OCB positively and significantly affects employee performance and mediates the effects of self-efficacy and organizational justice on employee performance, but does not mediate the effects of LOC. The analysis results show that organizational justice is the most influential variable in improving employee performance, both directly and through the mediating role of OCB. This study contributes to strengthening human resource studies through the role of OCB in improving performance. The findings of this study also provide guidelines for organizations in improving fairness practices to encourage positive work behavior.
PENGARUH KEPUASAN KARIR DAN JOB INSECURITY TERHADAP TURNOVER INTENTION DENGAN MEDIASI KOMITMEN ORGANISASI PADA PEGAWAI RS ISLAM PURWOKERTO Hidayah, Nisa; Widhiandono, Hengky; Darmawan, Akhmad; Utami, Restu Frida
Jurnal Maneksi (Management Ekonomi Dan Akuntansi) Vol. 15 No. 2 (2026): Jurnal Maneksi (Management Ekonomi Dan Akuntansi)
Publisher : Politeknik Negeri Ambon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31959/jm.v15i2.3741

Abstract

Introduction: This study aimed to examine the influence of career satisfaction and job insecurity on turnover intention, with organizational commitment serving as a mediating variable, among employees of Purwokerto Islamic Hospital.Methods: A quantitative approach was employed involving a population of 130 employees from various departments at Purwokerto Islamic Hospital, including nurses, pharmacists, PPJA (nurses in charge of care), ward heads or coordinators, laundry staff, cleaning service staff, medical records staff, and security guards. Data were collected using a questionnaire, and analyses were performed using SmartPLS version 3.Results: The research findings indicate that career satisfaction has a positive but insignificant effect on both organizational commitment and turnover intention. In contrast, job insecurity was found to have a positive and significant effect on turnover intention and organizational commitment. Organizational commitment was also shown to have a positive and significant effect on turnover intention. Additionally, the results indicated that organizational commitment did not mediate the relationship between career satisfaction and turnover intention, but did mediate the relationship between job insecurity and turnover intention. Overall, these findings highlight the critical roles of job insecurity and organizational commitment in efforts to reduce employee turnover rates. Keywords: Career Satisfaction, Job Insecurity, Organizational Commitment, SmartPLS, Turnover Intention
Co-Authors . Suwarsito ., Alfalisyado A.A. Ketut Agung Cahyawan W Abda Abda Ahmad Randy Ahmad Wahyudin Aisya, Sitti Alfandi, Asha Anggelina, Yosita Anggraini, Intan Anggun Puspita Ariani, Novita Arini Hidayah, Arini Aris, Muhammad Rizqie Arofah, Rifka Utami Aryawibawa, Anja Dwi Aryoko, Yudhistira Pradhipta Aryoko, Yudistira Pradipta ASEP SUPARMAN Bagis, Fatmah Bekti Divayani, Naelin Dinda Bima Cinintya Pratama Condro Nur Alim Darmawan , Althaffauz Najwa Dewijanti, Indah Dwiatmi Dini Siswani Mulia Dwi Kartika wahyuningsih Endang Saepudin, Endang Erny Rachmawati Fadzilah, Rizqiya Nur Fitriani, Azmi Fitriati, Azmi Galuh Widiyarti Hajar, Maya Umi Hani Mulyani, Hani Haryanto, Totok Hasanah , Uswatun Hendris Hendarsyah Kurniawan, Hendris Hendarsyah Hengky Widhiandono, M.Si. S.E. Heri Syahrian, Heri Hermin Endratno Hidayah, Nisa Indah Rahmawati Indahsari, Ninik Dewi Irfanesa, Irfanesa Jamhari Jamhari Jaroenwanit, Pensri Kharismasyah, Alfato Yusnar Kusbandian, Ani Leonardus B.S. Kardono Lia Meilawati Lotulung, Puspa Dewi N. Maharani, Adinda Safirah Maharani, Annisa Dwi Maharani, Wilia Krisna Maulida Nurul Innayah Maulidiyah Mawaddah, Apriani Medi Hendra Megawati Megawati - Megawati, Melliana, Sinta Bella Miftahuddin, Muchammad Agung Minarti Minarti Muhammad Hanafi Muhammad Nurdin Muji R., Tri Septin Mulyani, Hanny Mulyani, Hanny Naelati Tubastuvi Nina Artanti Nisa, Ainun Nofianingsih, Elsa Nugroho, Bambang Haryo Nur Umami, Kharisma Aulia Nurfiani, Aisah Nurhanifah, Salma Nurmalasari, Santy Nursanti, Tia Pratama, Bintang Rizki Pratiwi, Firda Ardianti Primahana, Gian Purnadi Purnadi, Purnadi Puspa Dewi Narrij Lotulung Putra, Nafis Mahesa Putragita, Yudhistira Rahmawati, Dwi Vina Rahmawati, Ika Yustina Randikaparsa, Irawan Ratna Kartika Wati Restu Frida Utami Rimbawan, Bagas Akbar Dwi Pangestu Rizna Triana Dewi sandra dewi Saputra, Eqwar Satria, Agri Bayu Setiyaningrum, Anggun Siska Liana Sofa Fajriah Soleh Kosela Sri Wahyuni Sri Wahyuni SUKIRNO Sukirno Sukirno Sunardi Sunardi Supriadi, Edi Susylowati, Dewi Suwarsito Suyoto Suyoto Teni Ernawati Tri Septin Muji Rahayu, Tri Septin Tri Utami Wahyudi Priyono Suwarso Wida Purwidianti Widyaningtyas, Dian Widyasmara, Meriska Yogi Widzayanto, Luthfi Arie Wiranti, Elza Devi Yasin, Roqi Yundari, Yundari Yuswandani, Arafah Esa