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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Brawijaya Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Degraded and Mining Lands Management Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Majalah Kedokteran Sriwijaya Sari Pediatri Biomedical Journal of Indonesia Paediatrica Indonesiana Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Alami Journal (Alauddin Islamic Medical) Journal Sainmatika: Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat SRIWIJAYA JOURNAL OF MEDICINE Majalah Kedokteran Andalas JURNAL MEDIA KESEHATAN Best Journal (Biology Education, Sains and Technology) MDJ (Makassar Dental Journal) Sriwijaya Journal of Surgery Indonesian Journal of Global Health research Jurnal Menara Medika Bioscientist : Jurnal Ilmiah Biologi MAHESA : Malahayati Health Student Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research International Journal of Islamic and Complementary Medicine Indonesian Community Journal Journal of Anesthesiology and Clinical Research Sanitasi: Jurnal Kesehatan Lingkungan Conferences of Medical Sciences Dies Natalis Jurnal Sehat Indonesia (JUSINDO) Jurnal Penyakit Dalam Indonesia Indonesian Journal of Biomedicine and Clinical Sciences Indonesian Journal of Global Health Research
Irfannuddin Irfannuddin
Faculty Of Medicine, Universitas Sriwijaya
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Faktor yang Memengaruhi Luaran Kualitas Hidup Anak dengan Hidrosefalus Setelah Pemasangan Shunt Ventrikulo-Peritoneal di Rumah Sakit Umum dr. Mohammad Hoesin Palembang Erni Desmita; Masayu Rita Dewi; Syarif Darwin; Trijoso Permono; Irfannuddin Irfannuddin; Raden Muhammad Indra
Sari Pediatri Vol 23, No 5 (2022)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp23.5.2022.299-305

Abstract

Latar belakang. Anak hidrosefalus dengan VP shunt dapat mengalami penurunan kualitas hidup (QoL) akibat berbagai faktor yang hingga kini belum banyak diteliti.Tujuan. Menilai luaran QoL anak hidrosefalus dengan VP shunt dan faktor yang memengaruhinya.Metode. Anak berusia 5-18 tahun dengan hidrosefalus yang dipasang VP shunt tahun 2010-2015 diidentifikasi melalui rekam medis. Orangtua kemudian diwawancarai dengan panduan kuesioner HOQ (hydrocephalus outcome questionnaire). Hasil meliputi skor QoL pada aspek fisik, kognitif, dan keseluruhan. Skor 0 menunjukkan luaran terburuk dan skor 1 terbaik.  Dilakukan analisis perbedaan skor berdasarkan faktor risiko (usia saat pemasangan, etiologi, adanya kejang dan komplikasi shunt) dan analisis kategorik berdasarkan pencapaian skor standar penelitian terdahulu (0,69).Hasil. Terdapat 95 anak yang diidentifikasi, 18 meninggal dan 46 dengan data tidak lengkap sehingga terdapat 31 anak yang dianalisis.  Skor HOQ yang didapatkan, yaitu fisik 0,75±0,27, sosial-emosional 0,78±0,22, kognitif 0,66±0,31, dan keseluruhan 0,73±0,25. Skor HOQ keseluruhan lebih rendah pada anak dengan komplikasi. Kejang (RR 2,52) dan komplikasi shunt (RR 4,85) berhubungan dengan luaran buruk. Analisis multivariat menunjukkan hanya komplikasi yang berhubungan dengan QoL buruk (adjusted OR 15,11).Kesimpulan. Luaran QoL ditemukan lebih baik dibandingkan penelitian sebelumnya. Kejang dan komplikasi shunt dapat berpengaruh negatif terhadap luaran QoL anak hidrosefalus dengan VP shunt.
Evaluation of CTEV Management in Children's Walking Ability Assessed by "BANGLA" Club Foot Tool Score System Irfannuddin Irfannuddin; Nur Rachmat Lubis; Febian Aji Wicaksono
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 4 No. 1 (2020): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v4i1.113

Abstract

Abstract Congenital talipes equinovarus (CTEV) or clubfoot is a congenital deformity that involves an abnormal position of the calcaneonaviculare complex. "Bangla clubfoot tool score system" is an assessment that indicates the effectiveness of CTEV management. The purpose of this study was to evaluate the management of CTEV on children's ability to walk as assessed by the Bangla clubfoot tool score system. A cross sectional study was conducted at the Hospital Dr. Mohammad Hoesin Palembang. There were 24 CTEV patients who received CTEV management before the age of 3 years and were not associated with a neurological disorder. A comparison of the average total Bangla clubfoot score tool system was analyzed by assessing parental satisfaction, walking ability and clinical examination. The majority of CTEV patients were women (58.3%) with and mostly being treated before 1 year old (79.2%). The most types of CTEV were bilateral (70.8%), and most of them performed surgery (66.7%). Assessment with the Bangla clubfoot tool system shows that the level of parental satisfaction is sufficient, gait is good, but physical foot examination is poor (20%). The score is influenced by age at first therapy and compliance using the brace. Parents must continue to support their children to undergo integrated management after therapy to maintain their walking ability.
Epidemiology and Risk Factors for Cervical Cancer Patiyus Agustiansyah; Rizal Sanif; Siti Nurmaini; Irfannuddin; Legiran
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 7 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i7.326

Abstract

Cervical cancer in Indonesia in 2018 ranks second in cancer in women in Indonesia with an incidence rate of 348.809 cases with a mortality rate of nearly 60% of the incidence, namely 207.210 deaths. Deaths from cervical cancer are projected to continue to increase and are estimated to reach 12 million deaths by 2030 if not treated properly. The incidence of cervical cancer in Indonesia is estimated to have 180.000 new cases per year and the death rate is thought to reach 75% in the first year. This death is mainly associated with the majority of newly diagnosed patients who are already at an advanced stage (70% of cases) and are already at the terminal stage at the time of diagnosis.
Human Papilloma Virus: Biomolecular Aspect Patiyus Agustiansyah; Rizal Sanif; Siti Nurmaini; Irfannuddin; Legiran
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 8 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i8.327

Abstract

HPV is a sexually transmitted virus, and high-risk HPV DNA was found in 99.7%of cervical cancer specimens. Within 12 to 24 months of exposure to the virus,90% of HPV infections disappear or become inactive. However, infection with high-risk strains of HPV persist which then increases the risk of progression to cervicalcancer. The detection of precancerous lesions consists of various methods,including pap smear (conventional or liquid-base cytology / LBC), visualinspection of acetic acid (IVA), visual inspection of lugoliodine (VILI), and HPV DNAtest (genotyping / hybrid capture).
WHO Global Strategy in Eradication of Cervical Cancer Patiyus Agustiansyah; Rizal Sanif; Siti Nurmaini; Irfannuddin; Legiran
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 9 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i9.328

Abstract

WHO has created a global strategy to accelerate the elimination of cervical canceras a public health problem and a world burden. Cervical cancer is a disease thatcan be prevented and cured, as long as it is detected early and treated effectively.Cervical cancer is also a disease that reflects global injustice. The burden isgreatest in low- and middle-income countries, where access to public healthservices is limited and screening and treatment for the disease has not been widelyapplied. In 2018, nearly 90% of all deaths worldwide occurred in low and middleincome countries. Furthermore, the proportion of women with cervical cancer whodie from the disease is more than 60% in these countries, more than double thenumber in many high-income countries, which is only 30%.
Screening for Cervical Cancer Patiyus Agustiansyah; Rizal Sanif; Siti Nurmaini; Irfannuddin; Legiran
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 10 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i10.329

Abstract

Screening is a public health intervention administered to a target population without symptoms. Screening is not performed to diagnose a disease, but to identify individuals with a higher likelihood of developing the disease itself or a precursor to the disease. Not all diseases are suitable for screening programs. The following criteria help determine whether a disease is suitable for a screening program: (1) The disease is bound to have serious consequences. (2) The disease must have a detectable preclinical and asymptomatic stage. (3) Treatment at the preclinical stage should influence the long-term course and prognosis of the disease being screened. (4) Care must be available and accessible to those who have a positive screening test. History, screening tests and treatment options for cervical pre-cancer meet these criteria.
Electrocardiography Predictive Value on Coronary Slow Flow Phenomenon Erwin Sukandi; Yudhie Tanta; Taufik Indrajaya; Ali Ghanie; Muhammad Irsan Saleh; Irfannuddin; Radiyati Umi Partan; Zulkhair Ali
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 3 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i3.454

Abstract

Coronary Slow Flow Phenomenon (CSFP) is characterized by the slow flow of contrast in one or more epicardial coronary vessels without evidence of coronary artery stenosis during coronary angiography procedures. CSFP is fairly common at the time of elective angiography with an incidence of around 7% and accounts for about 4% of hospitalized unstable angina cases. Coronary angiography is currently still the only effective way to detect CSFP, but this procedure is an invasive procedure with high costs, there is a risk of allergy to contrast. Electrocardiography (ECG), as a widely available, inexpensive, and simple modality is felt to be an attractive alternative in early detection of this abnormality. The ECG parameters on CSFP discussed in this study include; p-wave dispersion, QT interval dispersion, QRS intrinsic (Tpeak-Tenddeflection duration), and QRS fragmentation. Further studies are needed on the ECG image in CSFP so that in the future ECG can be a cheaper and non-invasive diagnostic modality for CSFP compared to coronary angiography.
The effect of regular aerobic exercise on urinary brain-derived neurotrophic factor in children Yunita Fediani; Masayu Rita Dewi; Muhammad Irfannuddin; Masagus Irsan Saleh; Safri Dhaini
Paediatrica Indonesiana Vol 54 No 6 (2014): November 2014
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (222.254 KB) | DOI: 10.14238/pi54.6.2014.351-7

Abstract

Background Nervous system development in early lifeinfluences the quality of cognitive ability during adulthood.Neuronal development and neurogenesis are highly influencedby neurotrophins. The most active neurotrophin is brain-derivedneurotrophic factor (BDNF). Physical activity has a positiveeffect on cognitive function. However, few experimental studieshave been done on children to assess the effect of aerobic regularexercise on BDNF levels.Objective To assess the effect of regular aerobic exercise onurinary BDNF levels in children.Methods This clinical study was performed in 67 children aged6-8 years in Palembang. The intervention group (n=34) engagedin aerobic gymnastics three times per week for 8 weeks, while thecontrol group (n=33) engaged in gymnastic only once per week.Measurements of urinary BDNF were performed on both groupsbefore and after intervention. Mann-Whitney and Wilcoxon ranktests were used to analyze the differences between groups.Results There was no difference in urinary BDNF levels betweenthe two groups prior to the intervention. After intervention,the mean urinary BDNF levels were significantly higher in theintervention group than in the control group, 230.2 (SD 264.4)pg/mL vs. 88.0 (SD 35.4) pg/mL, respectively (P=0.027). We alsofound that engaging in aerobic gymnastics significantly increasedurinary BDNF levels from baseline in both groups (P=0.001).Conclusion Regular aerobic exercise can increase urinary BDNFlevels and potentially improve cognitive function. Aerobic exerciseshould be a routine activity in school curriculums in combinationwith the learning process to improve children’s cognitive ability.
Is Duration of Endotracheal Tube Intubation Using a Video Laryngoscope Different with a Direct Laryngoscope in Elective Surgery Patients During Pandemic Covid-19? Zaky Hasan; Zulkifli; Agustina Br Haloho; Irfannuddin
Journal of Anesthesiology and Clinical Research Vol. 2 No. 1 (2021): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.057 KB) | DOI: 10.37275/jacr.v2i1.142

Abstract

Introduction: Aerosol box is a usefull tools to prevent aerosol and droplet contaminations during laryngoscopy and intubation in COVID-19 pandemic. Video laryngoscope is recommended during this era to increase the operator and patient’s distance during the procedure. However, many anesthesiologists still use direct laryngoscopes due to their availability and familiarity. This study aims to compare endotracheal tube intubation with video laryngoscope compared to direct laryngoscope in elective surgery patients. Methods: This study was a quasi-experimental study. The sample size in each group (video and direct laryngoscope) was 35 subjects. The primary outcome of this study was to compare the duration of intubation between video laryngoscope and direct laryngoscope, while the secondary outcome was to evaluate complications such as broken teeth and sore throat 24 hours post intubation. Results: Direct laryngoscope had shorter intubation duration than video laryngoscope [12.3 (8.9-21.0) vs 13.3 (11.4 – 21.6; p =0.07) respectively. Two complication reported on video laryngoscope groups. Conclusion: Duration of ETT intubation using a direct laryngoscope was shorter during intubation with aerosol box compared to video laryngoscope in elective surgery patients. The box which was being used may limit the space of movement making it difficult to intubate.
The Effects of Ketamin-Midazolam and Ketamin-Propofol on Bispectral Index Score as Sedatives During Bone Marrow Puncture Procedure Among Pediatrics Aldiar; Fredi Heru Irwanto; Andi Miarta; Irfannuddin
Journal of Anesthesiology and Clinical Research Vol. 2 No. 1 (2021): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.162 KB) | DOI: 10.37275/jacr.v2i1.143

Abstract

Background: Bone Marrow Puncture (BMP) is an invasive procedure associated with pain and anxiety. The ketamine-midazolam and the ketamine-propofol is an effectivecombination with minimal side effects. This study of the study aims to compare the effect of the combination of ketamine-midazolam and ketamine- propofol on sedation depth based on BIS in pediatric leukemia patients undergoing BMP. Methods: This study was a randomized controlled trial that was done single-blinded. The population was all pediatric patients diagnosed with leukemia who underwent BMP at RSMH and performed sedation. The research sample is the population that fulfill the inclusion and exclusion criteria. The sample size for each group was 25, with 50 Subjects in total. Sampling was done by block randomization. Results: This study found no differences in sex, age, and body weight between the two groups ([p=1.000], [p=0.845], and [p=0.147], respectively). In this study, there was no difference in mean MAP (p=0.592), oxygen saturation (p=0.164), heart rate (p=0.098), and respiratory rate (p=0.252) before intervention between the two groups. BIS value of the two groups had significant difference before and after the intervention where the two groups could reduce BIS to reach the optimal value of sedation <60 (p <0.05) There was no difference in BIS before intervention in the two groups (p=0.385). In this study, it was found that hypersalivation occurred more frequently in the ketamine-midazolam combination group. Conclusion: The combination of ketamine-midazolam and ketamine-propofol was equally good for sedation as indicated by a decrease in the mean BIS in patients undergoing BMP.
Co-Authors Ahmad Junaidi Ahmadi Ahmadi Aini, Lela Aldes Lesbani Aldiar Ali Ghanie Alifia Salsabila Amallia, RA Hoetary Tirta Andi Miarta Andi Saputra Andi Saputra Andika Okparasta Andini Agustina Anggraeni Janar Wulan Anggraini, Wieke Ardesy Melizah Kurniati Arwan Bin Laeto Athiah, Medina Budi Santoso Chairil Anwar Chalik, Muhammad Novran Citra Maharani Dahlan, Kemas Daniel Saputra Delvy Atriani Dewi Susan Diansari, Yunni Dwi Budi Santoso Eddy Ibrahim Eddy Mart Salim, Eddy Mart Eka Febri Zulissetiana Eka Febri Zulissetiana Elsafani Faddiasya Erni Desmita Erwin Sukandi Erwin Sukandi Esa Indah Ayu, Esa Indah Fachmi Idris Fatmawati Fatmawati Febian Aji Wicaksono FERLY OKTRIYEDI Ferry Usnizar Ferry Usnizar, Ferry Fredi Heru Irwanto Geo Vanda Ghina Kartika Handayani, Sri Hanna Marsinta Harahap, Huntari Hestiningsih, Tyas Husodo, Reyki Yudho Iche Andriyani Liberty, Iche Andriyani INDRA FRANA JAYA KK Indra, Syamsu Indrajaya, Taufik Indriyani Indriyani Jayawarsa, A.A. Ketut Karmila, Ariesti Kemas Dahlan Koibuchi, Noriyuki Krisna Murti Kusuma, Singgih Legiran Legiran Lela aini Lestari, Ajeng dwinta Lilik Pranata M. Hatta Dahlan M. Hatta Dahlan Mailan Alexander Mariana Mariana marisdina, selly Masagus Irsan Saleh Masayu Rita Dewi Masayu Rita Dewi Maya, Rachel Mega Gemala Miftahurrahmah Miftahurrahmah, Miftahurrahmah Minerva Riani Kadir Mohammad Zulkarnain Monica, Ricca Muhammad Hatta Dahlan Muhammad Irsan Saleh Muhammad Prima Cakra Randana Mukhlisa Muradi, Akhmadu Nadia Mutiara Ngudiantoro . Nur Arfian Nur Asini Nurhayati Damiri Nursiah Nasution Nursiah Nasution Nursiah Nasution, Nursiah Nurwany, Raissa Oktarizal, Hengky Pahrul, Dedi Patiyus Agustiansyah Poedji Loekitowati Hariani Pudi Handayani Putri Erlyn R.Kintoko Rochadi Rachel Maya Raden Muhammad Indra Radi Noorsyawal Radiyati Umi Partan Rini Nindela Rini Yana Risa Vera, Risa Rizal Sanif Roni Saputra Rukiah Chodilawati Sadakata Sinulingga Safri Dhaini Safyudin Saleh, Imran Santoso, Budi Shanty Chairani Sintiya Halisya Pebriani Siti Nurmaini Siti Rusdiana Puspa Dewi Siti Sarahdeaz Fazzaura Putri Subandrate Suheryanto Sukandi, Erwin Suprapti Suprapti Susanty, Tri Susilawati Susilawati Swanny Swanny, Swanny Syahputri, Rizka Aprillia Syarif Darwin Tanzila, R.A Tanzila, Raden Ayu Taufik Indrajaya Taufik Indrajaya Tri Suciati Trijoso Permono Trinovita Andraini Yenny Febriany Yuanita Windusari Yudhie Tanta Yudianita Kesuma, Yudianita Yunita Fediani Yunita Fediani Yunita Panca Putri, Yunita Yusuf Effendi Yususf, Fahmi Jaka Zaky Hasan Zulkarnain, Mohammad Zulkhair Ali Zulkifli