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Sri Purwaningsih
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Journal : Berkala Perikanan Terubuk

 1 
AKTIVITAS ANTIOKSIDAN PADA FORMULA TABLET TERIPANG KELING (Holothuria atra) Ahmad Fauzan Lubis; Sri Purwaningsih; Kustiariyah Tarman
Berkala Perikanan Terubuk Vol 44, No 2 (2016): Juli 2016
Publisher : Fakultas Perikanan dan Kelautan, Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.002 KB) | DOI: 10.31258/terubuk.44.2.51 - 69

Abstract

This study about activity of antioxidant aimed to determine the chemical characterization of sandfish, sandfish meat and sandfish powder, determine the best formulation in manufacturing Holothuria atra tablet based on DEPKES RI standard and to determine the antioxidant activity and the active compounds that act as antioxidants in the extract of Holothuria atra tablets. The method used in the manufacture of tablets is the direct compression method using 6 formulations to treat the kind of powder substance that is the ingredient of sandfish are intact and substances from the meat of sandfish. Tablet chosen based on the standards of the Ministry of Health that includes the physical characteristics of the test tablet and shelf-life stability. Tablet rivet sandfishtested the antioxidant activity by the method of 2,2-diphenyl-1-picrylhydrazyl (DPPH). Tests to determine the active compounds that act as antioxidants with thin layer chromatography (TLC) and bioautography antioxidants and also to determine the functional groups using analysis of Fourier Transform Infrared (FTIR). The yield of sandfish powder is considerably low. Yield of sandfish powder are 10.26% and sandfish meat powder are 9,82%. The protein content of sandfish powder are 60,89% lower compared to sandfish meat powders of 63,57%. Formula elected from the sandfish tablet test based on physical characteristics and stability test of the shelf life of the tablet is the formula A2 with the composition of the powder formulation Holothuria atra (25%), Ac-Di-Sol (2%), L-HPC (2%), Aspartame (0.5%), menthol (0.2%), talk (1%), magnesium stearate (1%) and lactose: mannitol (67.8%) and has antioxidant activity with IC50 value of 97.22 ppm. TLC test and Bio-autography showed that the class of antioxidant compounds are steroid, and suspected compounds at FTIR test, that act as antioxidants compound has similarities to the sterol class.
Co-Authors -, Maison AA Sudharmawan, AA Achirul Nditasari aditya yudha prawira soekarno Afifah, Shafa Sabitananda Agoes M Jacoeb Agoes Mardiono Jacoeb Agung Adi Nugroho, Agung Adi Ahmad Fauzan Lubis Alam, M. Sastra anak agung putu ayu puspita negara Anggri Alfira Yunita Assa Anggyani, Tasya Anna Carolina Erungan Annisa Rahma Fatmala Apit Setiani April Yanti, Fitri Arma Yenni, Yuli Asih Rahayu Ajeng Agesti Aswan, Dara Mutiara Aziza Putri Ningsi Azrifitria, Azrifitria Badeni Badeni, Badeni Bagus Sediadi Bandol Utomo Bambang Hariyadi Bambang Hariyadi Bambang P. Priosoeryanto Benny Manulang Bodová, Klára Darmaji Darmaji Darmaji, Darmaji Denny Susanto Dewa, Wisnu Jaka Dewi Ulfa Trisdiani Dewi, Tirta Kumala Dwi Agustiyani Effionora Anwar eka - deskawati Eka Ayuningrat Eka Deskawati Ekowati Handharyan Ekowati Handharyani ella - salamah ella - salamah Ella Salamah Ella Salamah Ella Salamah Ella Salamah Ella Salamah Ella Salamah Ellis Permatasari Ema Hastarini Entis Sutisna Erna Kristin Estelle Lilian Mua Evita Anggereini Evy Damayanthi Fahriza Sri Afni Febri Berthalita Pujaningsih Fitriany Podunge Gian P Apriyana Haerul Pathoni, Haerul Hebat Shidow Falah Heldalia Heldalia Hendri, Menza Hermawan Susanto Hidayati Hidayati I Gede Restawan I'tishom, Reny Indah Ria Lestari Janice Sepang Joko Santoso Jules Nurhatmi Juliana Neng Ribka Jumain Kustiariyah Tarman Lestari, Neneng Loviya, Mesi M. Nur Adnin Mala Nurilmala Maretty Twentyna Dolorosa Marna, Sri Mar’atun Rohmah Susanti Masikah Maylan Dewi Meilin Anggreyni MERLINDA KEMALA DEWI Mesi Loviya Muhammad Haris Effendi Hasibuan Mulyani, Nani Mustika, Gina Mutmainnah. HS Nehru Nikmawatisusanti Yusuf Nizel Huda Nizlel Huda Nova Natalia Beba Noveliyana, Yulista Nugroho, Cahyo Adhi Nurhikma Nurhikma Nurjanah Nurjanah Nurwulan, Afrida Olga Purnama Bakti Purwani Istiana Purwanti Ningsih Putra, Syailendra Putri Julia Mizulni Putri, Kinanti Eka Rahman, Dewi Rahmayani Rahmat Hidayat Rahmatia Garwan Rahmatia Garwan Ramacos Fardela Rayandra Asyhar Reki A. Febriani Rengganis, Inggi Reryd Arindany Wiryawan, Reryd Arindany Retno Wulan Dari Reza Dewantoro Riantoni, Cicyn Rieke Pernamasari Rika Kurnia Rimbawan , Rinto . Riska Fitriani Rita Arnila Riviani Riviani Riyan Triono Rosmawati Peranginangin Ruddy Suwandi Rustiyono, Rustioyono Sabarulin Sabarulin safrina dyah hardiningtyas Salsabila, Laili Salsabila, Putri Titania Sari, Jenni Sarjiya Antonius Sereli Pia SILMI MARIYA Sinulingga, Fahri Siti Madanijah Soesanta, Rasagama Putra Sri Retno Widyorini Sudarwan Danim Sugeng Heri Suseno Sukamto, Ika Sumiyarsi Syafrizal Ulum, Syafrizal Syeni Budi Anita TATI NURHAYATI Taufik Hidayat Tika A. Budiarti Tiza Yunisca Sari Tri Ariani Tri Ariani Upik Yelianti Wahyu Ramadhan Wini - Trilaksani Yanri Wijayanti Subronto Yennita Zulfarina, Zulfarina