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Pengembangan Formula Enteral Rendah Indeks Glikemik Berbasis Pangan Lokal Labu Kuning, Ubi Jalar Putih dan Susu Kedelai Nabila, Aprodhit Justicia; Nur Widiyaningsih, Endang; Sarbini, Dwi
Ghidza: Jurnal Gizi dan Kesehatan Vol. 9 No. 2 (2025): December
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/mxwdjp24

Abstract

Diabetes mellitus is a disease in Indonesia whose prevalence will continue to increase. Local food has the potential as an antidiabetic and antihyperglycemic. Pumpkin contains antioxidants that play a role in lowering blood sugar. In addition, fiber intake through nuts can help lower HbA1c levels. The purpose of this study was to determine and analyze viscosity, osmolality, flowability, nutritional content, and organoleptic tests. This study used an experimental method, by making 2 formulas and determining F2 as the recommended formula. The results of the analysis of nutritional substances were 1008.7 kcal of energy, 54.3 grams of protein, 29.5 grams of fat, 136.3 grams of carbohydrates, glycemic index 25.1, viscosity test 909.6 cP, osmolality 368 mOsm/Kg, flowability 0.01 cc/second, and no sediment. This enteral formula has the potential as a low glycemic index enteral food
Pengaruh Penambahan Ekstrak Akar Manis (Glycyrrhiza glabra L.) terhadap Aktivitas Antibakteri Permen Eritritol Salaf, Azizah Almisykatu; Sarbini, Dwi; Purwani, Eni
Ghidza: Jurnal Gizi dan Kesehatan Vol. 9 No. 2 (2025): December
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/ekxm8k57

Abstract

Dental caries is a chronic infectious disease that remains a major global health problem, primarily caused by Streptococcus mutans, a bacterium capable of forming dental biofilms. Preventive strategies can be developed through the use of natural non-cariogenic agents such as erythritol which exhibits anti-biofilm properties and licorice root (Glycyrrhiza glabra L.), which contains antibacterial compounds including flavonoids and saponins. This study aimed to evaluate the in vitro antibacterial potential of erythritol candy supplemented with licorice root extract against Streptococcus mutans. The study employed a Completely Randomized Design (CRD) consisting of four treatments with different concentrations of licorice root extract (0%, 2%, 3%, and 5%), along with a positive control (ampicillin) and a negative control (distilled water). Antibacterial activity was assessed using the well diffusion method and the inhibition zone diameters were analyzed statistically using Kruskal–Wallis test. The results showed that increasing the concentration of licorice root extract tended to enhance antibacterial activity with inhibition zones ranging from 1.00 ± 0.70 mm (2%) to 3.25 ± 1.76 mm (5%), although the differences were not statistically significant (p > 0.05). In conclusion, erythritol candy containing licorice root extract demonstrated potential antibacterial activity against Streptococcus mutans, although the effect was relatively weak. Further studies are recommended to determine the Minimum Inhibitory Concentration (MIC), evaluate anti-biofilm activity, and conduct in vivo testing to confirm its effectiveness under physiological conditions.
Hubungan Kecukupan Asupan Kalsium dan Zat Besi dengan Derajat Dismenorea Primer pada Mahasiswi Ilmu Gizi Universitas Muhammadiyah Surakarta Aprilia, Isna; Puspitasari, Dyah Intan; Mardiyati, Nur Lathifah; Sarbini, Dwi
JURNAL NUTRISIA Vol 27 No 2 (2025): September 2025
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29238/jnutri.v27i2.397

Abstract

Background: Dysmenorrhea, which is the condition of cramps or pain during menstruation, can be caused by various factors, including inadequate intake of calcium and iron. Objective: This study aims to analyze the relationship between the adequacy of calcium and iron intake and the severity of primary dysmenorrhea among nutrition students at Universitas Muhammadiyah Surakarta. Method: A cross-sectional design was used in this study with a sample of 140 female students at Nutrition Science in UMS. Simple random sampling was utilized for sample collection. The WaLIDD scale questionnaire was used to calculate dysmenorrhea scores, and the SQ-FFQ form was employed to assess the adequacy of calcium and iron intake over the past month. Data analysis was conducted using the Spearman Rank test. Results: The findings indicate that all students experienced dysmenorrhea, with an average calcium intake adequacy of 36.3% and an average iron intake adequacy also categorized as insufficient (42.4%). From the Spearman Rank test analysis, the adequacy of calcium intake related to dysmenorrhea showed a p-value of 0.450, and iron intake adequacy related to dysmenorrhea had a p-value of 0.244. Conclusion: There is no significant relationship between the adequacy of calcium and iron intake and the severity of primary dysmenorrhea among the nutrition students at Universitas Muhammadiyah Surakarta. It is recommended that future researchers can conduct blood serum measurements to assess calcium and iron levels to prevent dysmenorrhea.
PENYULUHAN ANEMIA PADA REMAJA SEBAGAI UPAYA PENINGKATAN PENGETAHUAN DAN PENCEGAHAN ANEMIA DI POSYANDU REMAJA “SEHATI” DESA TEMPEL KECAMATAN GATAK KABUPATEN SUKOHARJO Febrian Rida Saputra; Ilham Nur Ahmadyani; Pinkan Puspita Kinanty; Qoriah Titin Masyitoh; Maharani; Husna Ayu Amalia; Aisyah Sekar Widya Nansha; Mala Azzahra; Dewi Vinata; Maya Cristinawati; Shofia Nur Latifa; Tiara Fatmariska; Dwi Sarbini
Jurnal Berkawan: Jurnal Pengabdian kepada Masyarakat Vol 1. No. 3, September 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/berkawan.v1i3.6058

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Permasalahan gizi di Indonesia, khususnya anemia pada remaja putri, masih menjadi tantangan serius. Di Desa Tempel, Kabupaten Sukoharjo, prevalensi anemia tinggi disebabkan oleh asupan zat besi yang kurang dan kehilangan darah saat menstruasi. Tujuan kegiatan pengabdian ini adalah mencegah anemia melalui edukasi gizi seimbang dan suplementasi Tablet Tambah Darah (TTD). Metode yang digunakan meliputi survei lapangan, cek kesehatan, pre- test, edukasi, diskusi, dan pos-test. Sasaran kegiatan adalah remaja di Desa Tempel, yang dilakukan melalui pemeriksaan kesehatan dan penyuluhan tentang pencegahan anemia dengan menerapkan pedoman gizi seimbang. Hasil kegiatan menunjukkan peningkatan pengetahuan remaja tentang anemia. Hasil pre-test menunjukkan nilai rata- rata 8,22, sementara pos-test meningkat menjadi 8,94. Ini menunjukkan efektivitas pendekatan edukasi yang komprehensif dalam meningkatkan pemahaman remaja tentang pentingnya gizi seimbang dan konsumsi TTD. Kegiatan ini berhasil meningkatkan kesadaran dan pengetahuan remaja tentang pencegahan anemia. Saran yang diberikan adalah perlunya keberlanjutan program melalui Posyandu Remaja dan dukungan berkelanjutan dari kader kesehatan untuk memastikan kepatuhan konsumsi makanan bergizi dan TTD.
Hibiscus Sabdariffa Linn) terhadap NF-ĸβ, TNF-α dan ICAM-1 pada Human Umbilical Vein Endothelial Cells (HUVECs) Cultured yang dipapar Low Density Lipoprotein (LDL) Teroksidasi Sarbini, Dwi; Sargowo, Djanggan; Rohman, Muhammad Saifur
The Journal of Experimental Life Science Vol. 1 No. 2 (2011)
Publisher : Graduate School, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1353.389 KB) | DOI: 10.21776/ub.jels.2011.001.02.07

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Tujuan penelitian ini adalah mengetahui efek dan mekanisme kerja ekstrak teh Rosella merah (Hibiscus sabdariffa Linn) terhadap aktifasi NF-ĸβ dan ekspresi protein TNF - α serta ICAM-1 yang menjadi mediator inflamasi pada aterosklerosis. Penelitian ini menggunakan kultur sel endotel yang diisolasi dari vena umbilikalis manusia ( HUVECs). Kelompok kontrol digunakan HUVECs tanpa paparan ox-LDL (kontrol negatif) dan HUVECs yang dipapar 40 µgml-1 Ox-LDL (kontrol positif). Kelompok perlakuan adalah HUVECs yang dipapar dengan berbagai dosis teh Rosella merah (0,01 mgml-1, 0,005 mgml-1 dan 0,001 mgml-1) dan diberikan selama 2 jam sebelum dipapar ox-LDL. Pengukuran aktifasi NF-ĸβ dilakukan setelah 30 menit paparan Ox-LDL menggunakan imunohistokimia. Ekspresi protein TNF-α dan ICAM-1 diukur setelah 24 jam dipapar Ox-LDL menggunakan imunohistokimia. Berdasarkan analisis ANOVA (p<0.01) terdapat efek penghambatan ekstrak teh Rosella merah (Hibiscus sabdariffa Linn) terhadap aktifasi NF-ĸβ dan ekspresi protein TNF -α serta ICAM-1 yang manjadi mediator terjadinya inflamasi pada aterosklerosis melalui penghambatan aktifasi NF-ĸβ. Terdapat hubungan negatif antara aktifasi NF-ĸβ dan ekspresi protein TNF -α serta ICAM-1 dengan dosis ekstrak teh Rosella merah (Analisis Spearman's [p<0,01, Correlation Coeff = -1]). Kata Kunci: atherosklerosis, ICAM-1, NF-ĸβ, Ox-LDL, Rosella merah (Hibiscus sabdariffa Linn), TNF-α
Pengembangan Formula Enteral Untuk Penyakit Kanker Payudara Berbasis Tepung Kacang Merah dan Whey Protein Isolate (KAWPI) Luthfiya Ninda Ideliasari; Jihan Salsabila Adha; Dwi Sarbini
Pontianak Nutrition Journal (PNJ) Vol 9, No 1 (2026): Maret 2026
Publisher : Poltekkes Kemenkes Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/pnj.v9i1.2079

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Pasien kanker payudara rentan mengalami malnutrisi dan kaheksia karena kurangnya asupan oral. Terapi enteral berbasis tepung kacang merah dan whey protein isolate (WPI) dikembangkan sebagai alternatif formula untuk pasien kanker karena kaya Branched-Chain Amino Acids (BCAA). Penelitian ini bertujuan untuk mengkaji viskositas, osmolalitas, kandungan gizi, kadar air, karakteristik warna, analisis biaya produksi, dan daya terima formula enteral bubuk. Penelitian ini berupa eksperimental dengan 3 variasi perbandingan tepung kacang merah:WPI, yaitu F1 (19%:19%), F2 (20%:17%), dan F3 (22%:15%) serta kontrol formula komersial. Semakin tinggi proporsi tepung kacang merah, makin tinggi viskositas, kadar air, densitas energi, lemak, dan karbohidrat, tetapi semakin rendah daya terima formula enteral. Semakin tinggi proporsi whey protein isolate, maka semakin tinggi kandungan protein, BCAA, dan osmolalitas. Tidak ada pengaruh perbandingan kandungan formula terhadap karakteristik warna. Analisis biaya pembuatan enteral KAWPI didapatkan sebesar Rp14.000/320 mL. Formula terpilih adalah F2 karena memiliki daya terima cukup baik. nilai gizi, viskositas, osmolalitas, serta densitas energi yang memenuhi syarat ESPEN dan mendekati formula komersial meskipun kadar air cukup tinggi.
Pengaruh penambahan tepung daun kelor (Moringa oleifera) terhadap kandungan zat besi dan daya terima boba (tapioca pearl) Anggraeni Oktavia Rohmadhani; Dwi Sarbini
TEKNOLOGI PANGAN : Media Informasi dan Komunikasi Ilmiah Teknologi Pertanian Vol 17 No 2 (2026)
Publisher : Program Studi Ilmu dan Teknologi Pangan, Universitas Yudharta, Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35891/9be8tj65

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Iron deficiency anemia remains a major nutritional problem among adolescents, with a prevalence of 15.5% in Indonesia and 57.7% in Central Java. Boba (tapioca pearls), a beverage popular among adolescents, generally contains low levels of iron. Moringa leaves (Moringa oleifera) are known to be rich in iron, approximately 28 mg per 100 g in powder form, and thus have potential as a natural fortificant in boba products. This study aimed to analyze the effect of Moringa leaf powder addition on the iron content and acceptability of boba. This study employed an experimental design using a Completely Randomized Design (CRD) with one factor, consisting of four treatments: 0%, 5%, 10%, and 15% Moringa leaf powder addition, each with three replications. Iron content was analyzed using Atomic Absorption Spectrophotometry (AAS), while acceptability was evaluated by 35 semi-trained panelists using a 7-point hedonic scale. Data were analyzed using One Way ANOVA followed by the Least Significant Difference (LSD) test at a 5% significance level. The results showed that the addition of Moringa leaf powder significantly affected both the iron content and acceptability of boba (p<0.05). The iron content increased with higher concentrations of Moringa leaf powder, ranging from 0.059 µg/100 g to 3.637 µg/100 g. The highest acceptability was observed in the 5% treatment, categorized as “liked,” while the 15% treatment showed the lowest acceptance. In conclusion, the addition of 5% Moringa leaf powder is the optimal formulation, as it enhances iron content while maintaining consumer acceptability.
Efek Suplementasi Probiotik terhadap Indeks Massa Tubuh pada Dewasa Overweight Dwi Sarbini; Arini Dewi Safitri; Winda Wahyu Pratiwi
JURNAL RISET GIZI Vol. 13 No. 1 (2025): Mei 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrg.v13i1.12653

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Perubahan kebiasaan makan serta ketersediaan berbagai macam makanan tinggi energi membuat obesitas dan overweight  menjadi salah satu masalah serius. Prevalensi obesitas di Indonesia pada usia 18 tahun ke atas tergolong tinggi (23,4%) berdasarkan Survei Kesehatan Indonesia (2023). IMT membantu memantau status gizi pada dewasa gizi lebih dengan mudah. Gizi lebih ditandai dengan nilai IMT ≥25,0 kg/m2 untuk overweight dan ≥30,0 kg/m2 untuk obesitas. Orang dengan obesitas atau overweight memiliki rasio bakteri Firmicutes lebih banyak. Firmicutes meningkatkan penyimpanan energi di jaringan adiposa. Probiotik dapat memanipulasi mikrobiota usus untuk memulihkan ketidakseimbangan rasio bakteri Firmicutes sehingga dapat mengatasi gizi lebih. Untuk mengetahui efek suplementasi probiotik terhadap IMT dewasa gizi lebih. Menggunakan metode Literature Review terhadap 7 artikel desain penelitian Randomized Controlled Trial (RCT) 10 tahun terakhir (2014-2024) dipilih dari Pubmed dan Google Scholar reputasi internasional (Q1-Q4) dan nasional (S1-S3). Kata kunci digunakan probiotics, obesity, BMI, body mass index,  probiotik, obesitas, IMT. Sebanyak 5 artikel (71.42%) menyatakan ada penurunan IMT yang signifikan pada dewasa gizi lebih setelah suplementasi probiotik. Suplementasi probiotik dapat memberikan efek penurunan IMT signifikan pada penderita gizi lebih diimbangi dengan dosis 107 hingga 109  dan durasi pemberian 9-12 minggu atau jenis probiotik lebih dari satu.
Hubungan Kejadian Stres dan Kejadian Emotional Eating dengan Status Gizi pada Remaja SMA di Kecamatan Banjarsari Surakarta Devira Novi Aprillia; Dyah Intan Puspitasari; Dwi Sarbini
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 4 No. 4 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v4i4.5961

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Stress management or coping strategies of stress are individual efforts to manage the emotional pressure they experience. One form of coping strategy that is often practiced is emotional eating, the behavior of overeating arising from emotional factors. This behavior can affect nutritional status. Therefore, this study aims to determine the relationship between stress levels and emotional eating with nutritional status in high school adolescents. This type of research is observational analytic with a quantitative approach and the research design used a cross-sectional study design. This study was conducted in two locations, namely SMA Muhammadiyah PK Kottabarat Surakarta and MAN 1 Surakarta, with a total of 154 respondents selected using a proportional random sampling technique. The instruments used included the Depression Anxiety Stress Scale for Youth (DASS-Y 21) and the Adult Eating Behavior Questionnaire (AEBQ) as well as anthropometric measurements. Data analysis was carried out univariately and bivariately using the Spearman Rank correlation test. The research findings show no significant relationship between stress levels and nutritional status (p-value = 0.629), and between emotional eating and nutritional status (p-value = 0.051). Therefore, it can be concluded that there is no statistically significant relationship between stress events and emotional eating behavior and nutritional status in high school adolescents. This is because stress factors and emotionally triggered eating behavior do not directly affect adolescents' nutritional status in this context. These findings demonstrate the importance of monitoring students' stress levels, which can influence emotional eating, which in turn can affect nutritional status.
Proses Asuhan Gizi Terstandar pada Pasien Anemia dengan AKI dd ACKD, Suspek Sepsis, Wound Dehisensi dd Fistula Enterokutan: Laporan Kasus Alfi Miftahul Nikmah; Dwi Sarbini; Agus Prastowo
INSOLOGI: Jurnal Sains dan Teknologi Vol. 4 No. 3 (2025): Juni 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v4i3.5325

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Introduction: Acute Kidney Injury (AKI) is a sudden decline in kidney function, whereas Acute on Chronic Kidney Disease (ACKD) refers to an acute deterioration superimposed on pre-existing chronic kidney disease. Both conditions are associated with high mortality rates, especially when accompanied by other complications such as sepsis and postoperative conditions. Wound dehiscence is a postoperative complication characterized by the reopening of a surgical wound. This risk increases in patients with compromised immune status, sepsis, and chronic illnesses such as Chronic Kidney Disease (CKD). The aim of this case study is to provide nutritional care for a patient with Acute Kidney Injury (AKI) differential diagnosis of Acute on Chronic Kidney Disease (ACKD), suspected sepsis, wound dehiscence, suspected enterocutaneous fistula, and anemia, tailored to the patient’s clinical condition and nutritional needs. Case Presentation: An 18-year-old female student, referred to as Patient A, was diagnosed with Acute Kidney Injury (AKI) dd Acute on Chronic Kidney Disease (ACKD), suspected sepsis, wound dehiscence, suspected enterocutaneous fistula, and anemia. The patient had undergone exploratory laparotomy due to perforated appendicitis. Conclusion: The nutritional intervention provided was effective in improving the nutritional status of the patient with Acute Kidney Injury (AKI) dd Acute on Chronic Kidney Disease (ACKD), suspected sepsis, wound dehiscence, suspected enterocutaneous fistula, and anemia.
Co-Authors A Anifatussaa'dah Agus Prastowo Aisyah Sekar Widya Nansha Alfi Miftahul Nikmah Alifa, Elfrida Akmalia Andi Suhendi Anggraeni Oktavia Rohmadhani Anifatussaa'dah, A Anindya Rahmaningtyas Aprilia, Isna Ardalia Rinanda Oktaviani Arini Dewi Safitri Arman, Salsa Avia Atwal Arifin Aulia, Afifah Zakiyatul Ayu Masruro, Andita Azizatullatifah, Safira Basusena, Rahardian Surya Burhanudin Ichsan Cahyani, Teti Dwi Cintia, Fadhilla Fatwa Citra, Tia Mella Darmayanti, Putri Devira Novi Aprillia Dewi Vinata Dinda Agustin Sandra Djalal Fuadi Djanggan Sargowo Djanggan Sargowo Dyah Intan Puspitasari Dzafira, Laila Emy Huriyati Endah Kusuma Rastini Endang Nur Widiyaningsih Eni Purwani Erna Herawati Erna Herawati, Erna Fahriza Mei Trihatmoko Farida Nur Isnaeni Faridita khoirun Nisa' Febrian Rida Saputra Febrian, Novi Gita Noer Fidhia Nur Rifaini Firmansyah Firmansyah Fitriana Mustikaningrum Fitriani, Rizki Ainun Haliza Arzeti Nurseptiria Hanif, Adhwa Aulia Haryoto Haryoto Haryoto, H Haya Nabilah Utama HI, Marsilia Rosa Sinensis Hidayah Karuniawati Hilmi, Fatia Husna Ayu Amalia Ichsan, Burhanudin Ida Maesaroh Ida Maesaroh, Ida Ida Rohmawati, Ida Ilham Nur Ahmadyani Intan Nur Hidayati, Intan Nur IZZATUL FAJRIYAH Jihan Salsabila Adha Khusnul Khotimah khusnul khotimah Koesoemo Ratih Kusumastuti, Lina Ayu Laila Dzafira Lestari, Septiana Indah Lina Ayu Kusumastuti Listiana Masyita Dewi Luthfiya Ninda Ideliasari M Saifur Rohman M. Sholahuddin Mae Sri Hartati Wahyuningsih Maharani Mala Azzahra Mariska Sri Harlianti Marsilia Rosa Sinensis HI Marsya, Vitania Martianny, Dewi Nabila Maulanisa, Hasna Fitri Maya Cristinawati Mazaya, Saqya ‘Ainil Mochammad Imron Awalludin Mohammad Saifur Rohman Muhammad Saifur Rohman Muhtadi Muhtadi Muhtadi, M Muslihah, Sayyidah Nurul Muwakhidah Muwakhidah Nabila, Aprodhit Justicia Nisa', Faridita khoirun Novi Gita Noer Febrian Nur Achmad Nur Lathifah Mardiyati Nurdiana Nurdiana Nurdiana Nurdiana Nurdiana, N Nurseptiria, Haliza Arzeti Oktaviani, Ardalia Rinanda Permatasari, Qisthoni Pinkan Puspita Kinanty Pramudya Kurnia Pratiwi, Winda Wahyu Puryaningtias, Rini Dwi Puspitasari, Dyah Intan Putranto, Lintang Putri, Annisa Mulyarani Qoriah Titin Masyitoh Raafika Studiviani Rahardian Surya Basusena Ratnasari Diah Utami Rifaini, Fidhia Nur Rini Dwi Puryaningtias Rizki Ainun Fitriani Rusdin Rauf Rustiono, Dedy Sadewa, Hamim Safitri, Arini Dewi Salaf, Azizah Almisykatu Sayyidah Nurul Muslihah Selfahyasa Raharjo Septiyana, Nur Azizah Dewi Shofia Nur Latifa Studiviani, Raafika Sudrajah Warajati Kisnawaty Suharjo Suharjo Sukmawati, Maya Tafara Fikrama Depriasa Tanti Azizah Sujono Tata Indira Tia Mella Citra Tiara Fatmariska Tista Ayu Fortuna Titi A W Trihatmoko, Fahriza Mei Umi Kurniawati Utama, Haya Nabilah Vitania Marsya Widodo Widodo Winda Wahyu Pratiwi Winda Wahyu Pratiwi Wuryaningsih Dwi Lestari, Wuryaningsih Dwi Yusuf Sulistyo Nugroho