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All Journal Medical Journal of Indonesia Sari Pediatri Paediatrica Indonesiana Health Notions Medicinus : Jurnal Kedokteran World Nutrition Journal Jurnal Health Sains Proceedings of the International Conference on Nursing and Health Sciences eJournal Kedokteran Indonesia Jurnal Muara Medika dan Psikologi Klinis
Rini Sekartini
Department Of Child Health Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital
Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Exploring key cognitive indicators for practical use by parents in community setting Wiguna, Tjhin; Sekartini, Rini; Pasiak, Taufiq Fredrik; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0005

Abstract

The identification of child development milestones, specifically cognitive abilities, requires parental/caregiver awareness and knowledge. With the existence of multiple cognitive abilities such as attention and focus, memory, language, psychomotor skills, logic, reasoning, decision-making, problem-solving, social/emotional, there are multiple indicators to measure children's cognitive abilities. Pediatricians are the most knowledgeable and trusted authority to routinely screen and monitor the development of healthy children. Therefore, it is crucial that parents understand their children's developmental milestones so if they encounter anomalies, they can immediately consult with the professionals. This review compiles recently published research and current knowledge to examine potential key indicators of cognitive development in infants and children that can be utilized by parents and communities in an easily understood manner.
Biomarker Inflamasi (IL1?, IL6, TNF?, CRP) dan Mikronutrien (Zat Besi, Seng) pada Anak dengan Stunting Usia 6-59 Bulan: Sub Analisis SEANUTS II Ranto, Huminsa; Yuliarti, Klara; Munasir, Zakiuddin; Gunardi, Hartono; Wahidiyat, Pustika Amalia; Satari, Hindra Irawan; Sekartini, Rini
Sari Pediatri Vol 27, No 5 (2026)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.5.2026.316-22

Abstract

Latar belakang. Stunting memengaruhi 19,8% anak Indonesia usia di bawah lima tahun, menurut Survei Status Gizi Nasional tahun 2024. Sitokin proinflamasi (IL-1?, IL-6, TNF-?) dan defisiensi mikronutrien (zat besi, seng) diduga berperan dalam terjadinya stunting, terutama di negara berpendapatan menegah ke bawah, karena perannya dalam penghambat pertumbuhan tulang dan fungsi imun.Tujuan. Untuk mengetahui hubungan kadar sitokin proinflamasi, C-reactive protein (CRP), zat besi, dan seng dengan status stunting pada anak Indonesia usia 6-59 bulan.Metode. Data dikumpulkan dari sampel darah 100 anak Indonesia usia 6–59 bulan, dengan analisis statistik menggunakan uji chi-square, uji t, atau uji Mann-Whitney (p<0,05 dianggap bermakna).Hasil. Dari 100 subjek, 49 mengalami stunting dan 51 memiliki status gizi normal. Tingkat pendidikan dan pendapatan orang tua lebih rendah pada kelompok stunting (masing-masing p=0,019 dan p<0,001). Kadar median sitokin (IL-1?: p=0,344; IL-6: p=0,121; TNF-?: p=0,213), CRP (p=0,320), serta kadar mikronutrien (feritin: p=0,087; seng: p=1,000) tidak menunjukkan perbedaan bermakna antara kedua kelompok. Kesimpulan. Tidak ditemukan hubungan bermakna antara sitokin proinflamasi dan defisiensi mikronutrien yang diteliti dengan kejadian stunting, kemungkinan karena ukuran sampel yang terbatas dan bias perkotaan. Faktor sosial ekonomi berpengaruh signifikan terhadap stunting. Diperlukan penelitian longitudinal dengan sampel yang lebih besar untuk memperjelas hubungan tersebut.
Co-Authors Abdul Latief Adam Adam Adantio Rashid Santoso Aditya, Clarissa J. Ahmad Suryawan Aman B. Pulungan Amin Soebandrio Andintia Aisyah Santoso Andy Martahan Andreas Angela BM Tulaar Anindya, Isti Ari Prayitno Ari Prayogo Aria Kekalih Ariani Dewi Widodo Ariyanto, Ibnu Agus Armeilia, Rilie Asmoko Resta Asrawati Nurdin Astri Adelia Astri Dewina Bambang Tridjaja AAP, Bambang Tridjaja Basrowi, Ray Wagiu Batubara, Jose Benjamin Ngatio Bernie Endyarni Medise Bintang Pratiwi Cathrine Cathrine Chandra, Dian Novita Christine Natalita Clarissa Josephine Aditya Corrie Wawolumaja Corrie Wawolumaya Corry Wawolumaya Corry Wawolumaya Darmawan, Anthony C. Dian Kusumadewi Dian Milasari Diana Adriani Banunaek Dwi Putro Widodo Dyah Tunjungsari Eleonora Mitaning Christy Elina Waiman Elisa Harlean Erick Wonggokusuma Eva Devita Harmoniati Evan Regar Faisal Adam Fathan, Fariz Dwi Ghifari Nurullah Gunawan, Talitha Dinda Hannisa Rizka Setiawati Hardiono Poesponegoro Hartono Gunardi Hartono Gunardi Hartono Gunardi Hartono Gunardi Hartono Gunardi Hartono Gunardi Hartono Gunardi Helda Helda Helda Khusun Henry Riyanto Herwanto Herwanto Hesti Lestari Hesti Lestari Hindra Irawan Satari Ika Citra Dewi Ikhsan Johnson Imam D Imam N Irene Audrey Davalynn Pane Irene Yuniar, Irene Jeane Roos Ticoalu Jenni Kim Dahliana Jose RL Batubara Jusuf Kristianto Kartjito, Melissa Stephanie Levina Chandra Khoe Lily Rahmawati Listya Tresnanti Mirtha M. Triadi Wijaya Maelissa P. Ririmasse Martin Hertanto Maulina Rachmasari Medise, Bernie E. Melyarna Putri MF Conny Tanjung Mirtha, Listya T. Munasir, Zakiuddin Nadya, Ruth Nahla Shihab Nashrul Ihsan Ninik Mudjihartini Nurdina, Nazlah Nuri Indahwati Nuri Purwito Adi Nycane Nycane oedjatmiko oedjatmiko Oktarina, Molly Dumakuri Olfriani, Ciho Pasiak, Taufiq Fredrik Praevilia M Salendu Pramesthi, Indriya Laras Prastya, Reza Wahyu Dwi Pustika Amalia Wahidiyat, Pustika Amalia R.A. Deta Hanifah Ranto, Huminsa Ratna Djuwita Ray Wagiu Basrowi Retnaningdyah, Windri Ria Andreinie Rini Andriani Rini Mulia Sari Rismala Dewi Robert Sinto Ronny Suwento, Ronny Salma Oktaria Salsabila Yasmine Dyahputri Salsabila Yasmine Dyahputri Saptawati Bardosono Sarah Listyo Astuti Sari, Novika Purnama Siti Mirdhatillah Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Sri Hartati R. Suradijono Sri Sukmaniah Sudung O Pardede, Sudung O Sukamto Koesnoe Sundjaya, Tonny Surapsari, Juwalita Suzy Maria Tazkya Amany Thjin Wiguna Tjhin Wiguna Triatmoko, Barkah Trinovita Andraini Tutik Ernawati Wahyuni Indawati, Wahyuni Wangke, Lydia Wasito, Erika Widjaja, Melanie William Cheng Wirahmadi, Angga Yoga Devaera Yulianti Wibowo Yuliarti, Klara Yusra Zakiudin Munasir