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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Indonesian Journal of Chemistry Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JCRS (Journal of Community Research and Service) Jurnal Mandala Pharmacon Indonesia Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Sainstech Farma: Jurnal Ilmu Kefarmasian Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal Ilmiah Berkala Sains dan Terapan Kimia Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Abdimas Indonesian Journal Sevanam: Jurnal Pengabdian Masyarakat Jurnal Farmasi Klinik dan Sains Journal of Pharmaceuticals and Natural Sciences al Kimiya : Jurnal Ilmu Kimia dan Terapan Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan Jurnal Abdita Naturafarm Jurnal Riseta Naturafarm
Herman Herman
Fakultas Farmasi Universitas Mulawarman
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Antibacterial Activity of Kersen Leaf Extract (Muntingia calabura Linn.) Against Salmonella typhi and Staphylococcus aureus Using Bioautography Method Maharani, Dhea Nur Fadillah; Almeida, Maria; Arifian, Hanggara; Ibrahim, Arsyik; Herman, Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 2 No. 2 (2025): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v2i2.8694

Abstract

Kersen (Muntingia calabura Linn.) is a plant with a large population in Indonesia. Thus, the abundance of this number can be used as a source of raw materials for medicine. Kersen has many benefits, especially in the leaves as an antibacterial. The purpose of this study was to determine the extract yield, compound groups, and antibacterial activity against Salmonella typhi and Staphylococcus aureus. Antibacterial activity was measured using the well method and TLC Bioautography. The results showed an extract yield of 19.77%. The TLC profile identified flavonoid, alkaloid, tannin, and steroid compound groups. Kersen leaf extract showed antibacterial activity against Salmonella typhi and Staphylococcus aureus with moderate to strong antibacterial power at concentrations of 40%, 50%, and 60%. The groups of compounds suspected of playing a role in antibacterial activity are flavonoids, alkaloids, tannins, and steroids. This study shows that kersen leaf extract has the potential as an antibacterial agent against Salmonella typhi and Staphylococcus aureus bacteria.
Edukasi Kefarmasian sebagai Upaya Preventif Diabetes Mellitus dan Gout di Kelurahan Mangkupalas Samarinda Seberang Anggreini, Putri; Rijai, Laode; Herman, Herman; Ibrahim, Arsyik; Rashif Rijai, Hifdzur; Rozi, Fahrul; Rezky Khairun Nisaa, Nur; Olivia Siregar, Vita; Badawi, Satriani
Abdimas Indonesian Journal Vol. 5 No. 1 (2025)
Publisher : Civiliza Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59525/aij.v5i1.769

Abstract

Pharmaceutical education is one of the preventive efforts to enhance community understanding of Diabetes Mellitus (DM) and Gout, whose prevalence continues to rise in society. Mangkupalas Village, Samarinda Seberang, was selected as the location for community service based on the high risk of DM and Gout influenced by dietary patterns, lifestyle, and a lack of health education. The service method included delivering preventive material on DM and Gout by resource persons, followed by a discussion session. Questionnaires were distributed before and after the educational activities. The results showed an average pre-test score of 48.8 and an average post-test score of 60.0, indicating an increase in community knowledge after receiving pharmaceutical education. Additionally, residents showed enthusiasm for implementing healthy lifestyle changes. In conclusion, pharmaceutical education is effective in raising awareness and knowledge about DM and Gout among the community. This community service activity can serve as a continuous effort to reduce the risk of chronic diseases, particularly among the residents of Mangkupalas Village, Samarinda.
Formulasi Sediaan Toner Ekstrak Bunga Telang (Clitoria ternatea) sebagai Antioksidan Kulit Herman, Herman; Almeida, Maria; Devara, Rachel; Bone, Mahfuzun; Zamruddin, Nur Masyithah
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 1 (2025): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i1.811

Abstract

Bunga telang (Clitoria ternatea) dikenal sebagai tanaman obat yang mengandung antosianin dengan potensi sebagai antioksidan. Penelitian ini bertujuan merumuskan dan mengevaluasi sediaan toner berbahan dasar ekstrak bunga telang sebagai antioksidan untuk perawatan kulit. Ekstrak diperoleh melalui maserasi menggunakan etanol 70%, kemudian diuji kandungan metabolit sekunder serta aktivitas antioksidan dengan metode DPPH. Toner diformulasikan menggunakan basis gliserin 5% dan dievaluasi melalui uji organoleptik, pH, stabilitas, dan aktivitas antioksidan selama empat siklus suhu. Hasil menunjukkan rendemen ekstrak sebesar 7,88% dengan kandungan alkaloid, flavonoid, terpenoid, dan tanin. Aktivitas antioksidan ekstrak tergolong kuat dengan nilai IC50 sebesar 67,73 ppm dan persen peredaman tertinggi 30,603% pada konsentrasi 90 ppm. Toner dengan formula basis gliserin 5% memenuhi kriteria organoleptik dan menunjukkan aktivitas antioksidan tertinggi sebesar 25,145% pada suhu 4?, meskipun nilai pH sediaan belum seluruhnya berada dalam rentang ideal.
Pengayaan Polifenol Total dari Daun Kadamba Menggunakan Metode Ekstraksi Berbantu Mikrowave Berbasis Pelarut Hijau: Total Polyphenols Enrichment from Mitragyna speciosa Korth Havil Leaves Using Green Solvent Based Microwave-assisted Extraction Method Ahmad, Islamudin; Yusniah, Andi; Nur, Yuspian; Prabowo, Wisnu Cahyo; Herman
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15035

Abstract

The present study aims to optimize the natural deep eutectic solvent (NADES) as a green solvent-based microwave-assisted extraction (MAE) of total polyphenols content (TPC) from Mitragyna speciosa Korth Havil leaves using response surface methodology (RSM). Preparation of natural deep eutectic solvent (NADES) as a green solvent was performed by melting the two-component of malic acid and glucose using a magnetic stirrer. The leaves sample was extracted using the NADES-MAE method with various extraction conditions with four factors and three levels (Box Behnken Design) and optimized using RSM with licensed software of Design Expert V12. TPC was determined using a Folin-Ciocalteau reagent and absorbance was measured on a UV-VIS spectrophotometer at 770 nm and gallic acid as a standard. This study was obtained the optimum extraction conditions include: NADES ratio (malic acid: glucose) of 1:2 g/g, 50% microwave power, a solvent-sampel ratio of 12:1 mL/g, and extraction time for 7 minutes. The optimum conditions were obtained according to the equation formula: TPC = 165.17 – 33.97X1 + 38.36X2 – 6.08X3 + 16.12X4 – 62.77X1X2 + 79.61X12X2, where a R2 value = 0.7102 with a TPC prediction of 402.087±43.81 mg GAE/g sample. These conditions can be used to extract TPC from this plant efficiently, quickly, easily, and environmentally friendly.
Workshop Pembuatan Gummy Candy Madu Kelulut Di Desa Bangun Rejo Kabupaten Kutai Kartanegara Samsul, Erwin; Junaidin, Junaidin; Rijai, Laode; Ibrahim, Arsyik; Herman, Herman; Rusli, Rolan; Ahmad, Islamudin; Febrina, Lizma; Farah, Harra Ismi; Hikmawan, Baso Didik; Rija’i, Hifdzur Rashif; Supriatno, Supriatno; Rusman, Arman; Almeida, Maria; Riki, Riki; Arifuddin, M; Bone, Mahfuzun; Arifian, Hanggara; Setiawaty, Agus
Journal of Community Research and Service Vol. 9 No. 2: July (2025)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jcrs.v9i2.69839

Abstract

A workshop on making gummy candy based on stingless bee honey was held in Bangun Rejo Village, Kutai Kartanegara Regency, as an effort to empower the community through innovation in locally processed food products. The aim of this activity was to improve the skills of MSME actors and village residents in producing stingless honey gummy candy, and to elevate the added value of local honey. The methods used included a short theoretical session about the composition of stingless bee honey and the technical process of gummy candy production, a live demonstration, group practice among participants, as well as evaluation via pre-test and post-test on understanding and skills. The workshop was attended by 50 participants from various MSMEs and community groups. Results showed that after training there was an increase in participant understanding by approximately 75% compared to before the training. Furthermore, participants succeeded in making gummy candy with a chewy texture, the natural sweetness of stingless bee honey, and a distinctive aroma that was well accepted in organoleptic tests. This workshop made a tangible contribution to local product diversification, increasing production capacity, and the potential enhancement of village income through signature products based on stingless bee.
Effectivity of Antihypertensive Drugs Use in Pregnant Woman with Diagnoses of Preeclampsia Hospitalized at Abdoel Wahab Sjahranie Hospital and Inche Abdoel Moeis Hospital Samarinda City: Efektivitas Penggunaan Obat Antihipertensi Pada Ibu Hamil dengan Diagnosa Preeklampsia Rawat Inap di RSUD Abdoel Wahab Sjahranie dan RSUD Inche Abdoel Moeis Kota Samarinda Difta, Rismania Shita; Mus, Nurul Muhlisa; Almeida, Maria; Herman, Herman
Jurnal Riseta Naturafarm Vol. 2 No. 2 (2025): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrn.v2i2.7384

Abstract

The use of appropriate and effective antihypertensive drugs is needed so that blood pressure in preeclampsia patients can be controlled so as not to endanger the condition of the mother and fe-tus. This study aims to determine the rationality and effectiveness of the use of antihypertensive drugs at RSUD Abdoel Wahab Sjahranie and RSUD Inche Abdoel Moeis in the period January 2022 - December 2023 which was carried out through retrospective data observation of hospital-ized patients with a total of 12 samples (RSUD Abdoel Wahab Sjahranie) and 10 samples (RSUD Inche Abdoel Moeis). The results of the evaluation of the rationality of antihypertensive drugs used were assessed as appropriate patients, appropriate indications, appropriate drugs, ap-propriate doses and appropriate time intervals of administration each by 100% based on the 2016 POGI guideline, Hospital Formulary, 2023 SOMANZ guideline, 2021 ISSHP guideline, and 2019 ACOG guideline. The effectiveness of using Methyldopa monotherapy showed better blood pressure reduction results (34.81/12.37 mmHg) than Nifedipine (21.41/5.6 mmHg), while the combination of Nifedipine and Methyldopa showed greater results than monotherapy (38.5/15.2 mmHg).
Alkaloid Profiling of Kadamba (Mitragyna speciosa Korth. Havil.) Leaves through Chromatographic Separation and UV-Vis Spectrophotometery Analysis Arifuddin, M.; Azmi, Fatur Rahman; Iswahyudi, Iswahyudi; Bone, Mahfuzun; Farrah, Harra Ismi; Arifian, Hanggara; Almeida, Maria; Rusman, Arman; Samsul, Erwin; Riki, Riki; Rija'i, Hifdzur Rashif; Hikmawan, Baso Didik; Junaidin, Junaidin; Febrina, Lizma; Rusli, Rolan; Ibrahim, Arsyik; Ahmad, Islamudin; Herman, Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 2 No. 3 (2025): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v2i3.44

Abstract

Mitragyna speciosa Korth. berasal dari famili Rubiaceae yang banyak tumbuh di daratan negara-negara Asia Tenggara. Tumbuhan ini selain disebut Kratom, khususnya di daerah Kalimantan Timur dikenal juga dengan nama "Kadamba". Mitragyna speciosa Korth. belongs to the Rubiaceae family and is widely found in the mainland of Southeast Asian countries. This plant, known as Kratom, is also referred to as "Kadamba" in East Kalimantan. Kadamba has been used for generations as a traditional medicine and contains predominantly alkaloid compounds, which generally function as analgesics, antitussives, antidiarrheals, adrenergic agents, antimalarials, antibacterials, and antinociceptives. The aim of this research is to determine the isolation and identification methods for alkaloid compounds in Kadamba leaves. In this study, extraction was performed using methanol solvent, followed by fractionation using Vacuum Liquid Chromatography (VLC) and Column Chromatography (CC) with gradient eluents: 100% hexane, n-hexane : Ethyl Acetate (5:1, 1:1, 1:5), 100% Ethyl Acetate, Ethyl Acetate : Methanol (1:1, 1:5), and 100% Methanol. The compounds were then identified using Thin Layer Chromatography (TLC). The isolation process used preparative Thin Layer Chromatography (PTLC) with eluent n-hexane: ethyl acetate: 25% ammonia (6.5:3:0.5 v/v/v), and the spots were observed under UV light at 245 nm and 366 nm. The visible spots were sprayed with Dragendorff's reagent to identify the alkaloid compounds. The results showed that the UV-Vis spectrophotometric characterization of isolate B6-b had two peaks at wavelengths of 288 nm and 294 nm.
CLINICAL OBSERVATION OF MALONDIALDEHYDE FREE RADICAL COMPOUND LEVELS IN URINE SAMPLES OF SMOKERS AND NON SMOKERS GIVEN JUICE WATERMELON (Citrullus Lanatus) ZAMRUDDIN, NUR MASYITHAH; Dwi Septiani, Kadek Ayu; Almeida, Maria; Rusman, Arman; Jafar, Fahriani Istiqamah; Herman, Herman
Jurnal Farmasi Klinik dan Sains Vol 5, No 2 (2025): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v5i2.1933

Abstract

Malondialdehid (MDA) merupakan biomarker stres oksidatif akibat keberadaan radikal bebas dalam tubuh. Penelitian ini bertujuan untuk mengetahui gambaran kadar MDA urin dan asam urat pada responden perokok dan non perokok dan mengetahui perubahan kadar MDA urin dan asam urat pada responden perokok dan non perokok yang diberikan minuman antioksidan jus buah semangka (Citrullus lanatus). Metode penelitian yang digunakan adalah pre-post test design. Hasil penelitian menunjukkan bahwa kadar MDA urin pada perokok aktif dan bukan perokok sebelum pemberian jus semangka adalah 2,666 nmol/mL dan 1,506 nmol/mL, sedangkan hasil penelitian setelah pemberian jus semangka pada hari ke-7 pada responden adalah 0,799 nmol/mL dan 0,539 nmol/mL. Sedangkan kadar asam urat awal masing-masing responden sebesar 7,5 mg/dL dan 6,6 mg/dL dan hasil penelitian setelah pemberian jus pada hari ke-7 kepada responden sebesar 6,1 mg/dL dan 5,7 mg/dL. Pada hasil analisis statistik menggunakan uji-t didapatkan nilai p0,05 pada kadar asam urat perokok dan nilai p
Clinical Observation of the Effect of the Combination of Red Drag-on Fruit Juice (Hylocereus polyrhizus) and Honey on Lowering Blood Pressure: Observasi Klinik Pengaruh Kombinasi Jus Buah Naga Merah (Hylocereus polyrhizus) dan Madu Terhadap penurunan tekanan darah Saputri, Meutia Ridha; Fadraersada, Jaka; Almeida, Maria; Herman
Jurnal Riseta Naturafarm Vol. 3 No. 1 (2026): J Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrn.v3i1.0109

Abstract

Pitaya (as known as red dragon fruit in Indonesia) and honey contain high polyphenols and flavo-noids as the main source of antioxidants. Antioxidant compounds in pitaya and honey can reduce systolic and diastolic blood pressure. The aim of this study were to determine the characteristics of gender, age, and Body Mass Index of hypertensive respondents and determine the effect of the combination of pitaya juice and honey on the reduction in blood pressure and Body Mass Index for geriatric hypertensive respondents at the Puskesmas Sempaja Samarinda. This research used quasi-experimental method and data was taken with pre-test and post-test procedures. The data of respondent characteristics shown are women got the highest percentage of 58.9%, middle age of 57.8% and normal weight category (BMI) of 40.7%. The results of descriptive analysis in sys-tolic and diastolic blood pressure from pre-test are 138.64 mmHg and 82.28 mmHg, the post-test are 132.55 mmHg and 77.85 mmHg and decrease in the Body Mass Index of 0.22 kg/m2. The conclusion of this research is the combination of pitaya juice and honey was able to reduce the blood pressure and Body Mass Index
Clinical Observation of the Effect of the Combination of Red Drag-on Fruit Juice (Hylocereus polyrhizus) and Honey on Lowering Blood Pressure: Observasi Klinik Pengaruh Kombinasi Jus Buah Naga Merah (Hylocereus polyrhizus) dan Madu Terhadap penurunan tekanan darah Saputri, Meutia Ridha; Fadraersada, Jaka; Almeida, Maria; Herman
Jurnal Riseta Naturafarm Vol. 3 No. 1 (2026): J Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrn.v3i1.0109

Abstract

Pitaya (as known as red dragon fruit in Indonesia) and honey contain high polyphenols and flavo-noids as the main source of antioxidants. Antioxidant compounds in pitaya and honey can reduce systolic and diastolic blood pressure. The aim of this study were to determine the characteristics of gender, age, and Body Mass Index of hypertensive respondents and determine the effect of the combination of pitaya juice and honey on the reduction in blood pressure and Body Mass Index for geriatric hypertensive respondents at the Puskesmas Sempaja Samarinda. This research used quasi-experimental method and data was taken with pre-test and post-test procedures. The data of respondent characteristics shown are women got the highest percentage of 58.9%, middle age of 57.8% and normal weight category (BMI) of 40.7%. The results of descriptive analysis in sys-tolic and diastolic blood pressure from pre-test are 138.64 mmHg and 82.28 mmHg, the post-test are 132.55 mmHg and 77.85 mmHg and decrease in the Body Mass Index of 0.22 kg/m2. The conclusion of this research is the combination of pitaya juice and honey was able to reduce the blood pressure and Body Mass Index
Co-Authors Abdul Mutalib Abdul Mutalib Abdul Mutalib Agung Endro Nugroho Agus Setiawaty Almeida, Maria Andi Tenri Kawareng Anggreini, Putri Anni Anggraeni Anni Anggraeni Anni Anggraeni Arie Hardian Arifian, Hanggara Arifuddin, M Arifuddin, Muhammad Arsyik Ibrahim Azmi, Fatur Rahman Badawi, Satriani Baso Didik Hikmawan Bohari Yusuf Bone, Mahfuzun Dayuh Anggun Mandalika Devara, Rachel Dewi Mayasari Difta, Rismania Shita Dwi Septiani, Kadek Ayu Erwin Samsul Fadraersada, Jaka Fahriani Istiqamah Jafar Fahrul Rozi Faizah Hanan Lestari Farah Erika Farah, Harra Ismi Farrah, Harra Ismi Febrianto Ubang Fika Aryati Firzan Nainu Haeruddin Haeruddin Haeruddin Haeruddin Haeruddin Haeruddin Hanggara Arifian Helga Lisu Sarira Helmi Helmi Henny Hidayah Herlita Gasella Salsabila Hifdzur Rashif Rija’i Husein Hernadi Bahti Ibrahim, Arsyik Ilimu, Edi Indriana Tasya Islamudin Ahmad Islamudin Ahmad Iswahyudi Iswahyudi Iswahyudi ISWAHYUDI ISWAHYUDI Ivan Satria K.P. Jafar, Fahriani Istiqamah Junaidin Junaidin Junaidin, Junaidin Khofifah Nur Oktavia Laode Rijai Laode Rijai Laode Rijai Lia Puspitasari Lisda Virdasari Lizma Febrina M. Arifuddin, M. Maharani, Dhea Nur Fadillah Maryam Jamila Arief Maryam Jamila Arief Mirhansyah Ardana Mitha Saputri Mohd Azlan Nafiah, Mohd Azlan MUHAMMAD AMIR MASRUHIM Muhammad Faisal Muhammad Faisal Muhammad Yusuf Muljadji Agma Mus, Nurul Muhlisa Nia Audina Nilam Ratna Rizkyanti Nisa Naspiah Noviyanty Indjar Gama Nur Masyithah Zamruddin Nur Masyithah, Z Nur Zakiyah Darajat Nur, Yuspian Nurdeni, Nurdeni Nurdewi Halik Nurdianah Abdul Kadir Nurfitri Nurfitri Nurul Fitriani Nurul Fitriani Olivia Siregar, Vita Otsuka Khaera Nurmala Pasaribu, Handayani Prabowo, Wisnu Cahyo R. Ukun M.S. Soedjanaatmadja Rahmadani, Agung Rashif Rijai, Hifdzur Retna Putri Fauzia Rezky Khairun Nisaa, Nur Ridhotulloh, Yusuf Isro Rija'i, Hifdzur Rashif Rijai, Hifdzur Rashif Rija’i, Hifdzur Rashif Riki RIKI RIKI, RIKI Rimba Hamid Rolan Rusli Rusman, Arman Salam, Supriatno Sari, Indah Dewi Selvi Jumiatul Astati Selvi Megawati Senadi Budiman Sukemi Sukemi Suparningtyas, Juniza Firdha Supriatno Supriatno Salam Suwijiyo Pramono Usman Usman Vina Maulidya Vita Olivia Siregar Wahyu Yunita Lestari Yusniah, Andi Zahra Praselya Zamruddin, Nur Masyithah Zuhrotun Nafisah Zuliayu Arizka Pratiwi