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Analysis of Factors Affecting CD4+ Increase in HIV / AIDS Patients Receiving ARV Therapy Budi, Dini Wurnaning; Rahayu, RR. Sri Ratna; Yuniastuti, Ari
Public Health Perspective Journal Article In Pres August 2021
Publisher : Universitas Negeri Semarang

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Abstract

Acquired immunodeficiency syndrome (AIDS) is a collection of symptoms and infections that arise due to damage to the human immune system due to infection with the Human Immunodeficiency Virus (HIV). The number of HIV patients at Panti Wilasa Hospital continues to increase from every year in 2018 the number is 150 HIV / AIDS patients. The purpose of this study was to analyze the factors that influence the increase in CD4+ levels of HIV / AIDS patients receiving ARV therapy at Panti Wilasa Citarum and Dr. Cipto Hospitals Semarang. This research is a quantitative study, with a cross-sectional approach. The minimum sample of the study was 38 respondents using simple random sampling technique. Data analysis in this study using Multiple Logistic Regression. The results of the study, the most influential variables were clinical stage (p=0.000), and concomitant disease tuberculosis (p = 0.14) on the increase in CD4+ levels. The risk of HIV / AIDS transmission in Indonesia is the highest and until now, there is no cure for HIV. ARV therapy can inhibit the development of the HIV virus, giving ARVs is given if the CD4+ level is less than 500 cells / mm3, or there are other conditions in HIV patients. The importance of early awareness in ARV therapy for early initiation of ARVs is proven to be clinically beneficial, useful for prevention, increase life expectancy and reduce the incidence of HIV-related infections.
The Effect of Monosodium Glutamate on the Lee Index in Mice (Mus Musculus) Innayah, Nurul; Azam, Mahalul; Yuniastuti, Ari
Public Health Perspective Journal Article In Pres August 2021
Publisher : Universitas Negeri Semarang

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Abstract

Obesity is the buildup of abnormal or excessive fat that can be detrimental to health. High flavor-flavoring consumption or monosodium glutamate (MSG) is one of the factors contributing to the increase in obesity of the Indonesian population. This study aims to analyze the effect of MSG on giving to Lee's index in mice. The Lee index is one of the indicators in determining mice obesity. The type of research was pure laboratory experimental research, with the design Post Test Only Control Group. The mice were divided into four random clusters. Each cluster contained six mice. The control cluster was given standard feed + drink, cluster I was given standard feed + drink + MSG 10.4 mg / 20gbb, cluster II was given standard feed + drink + MSG 20.8 mg / 20gbb and cluster III was given standard feed + drink + MSG 26 mg / 20gbb for 28 days. Day 29 was the weight lift and the length to calculate the lee index. Data normality analyze used Spahiro Wilk and the homogeneity test used Levene's test. The results of the variance homogeneity test showed that the value of p = 0.374, so that the lee index value of each cluster did not have a significant difference (p> 0.05). Then continued with the One Way Anova test, the value of p = 0.246 (meaningful if p <0.05). It could be concluded that the provision of MSG 4 grams, 8 grams, and 10 grams did not have a significant effect on the lee index value in mice between the control cluster and the treatment cluster.
Description of Health and Clean Life Behaviors and Improving Student Cognitiveness in Islamic Primary School Pramusinta, Linda; Yuniastuti, Ari; Rahayu, Sri Ratna
Public Health Perspective Journal Article In Pres August 2021
Publisher : Universitas Negeri Semarang

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Health and Clean Life Behaviors (CHLB) should be applied in daily life so that diseases cannot easily infect human. Children aged from 7 until 14 years have to be taught with CHLB concretely and theoretically. This research explores the general CHLB of Islamic Primary School Gunungpati, Semarang, and to improve CHLB cognition by applying Asset-based Community Development (ABCD). This research applied the mixed-method of qualitative and quantitative methods. The sample of the research consisted of the fifth-graders of the school. They were taken by purposive sampling.  The research subjects consisted of principals, home teachers, sports teachers, and various cognitive categorized learners. The applied instruments were interview guideline and CHLB cognitive test. The techniques of analyzing data were triangulation and test of CHLB cognitive improvement by using N-Gain test. The findings showed that the teaching-learning processes, especially dealing with CHLB, were still teacher-centred learning and lack of maximizing CHLB. In the learners' cognitive improvement test, the learners had improvements with a score of N-Gain test 0.47. It meant the improvement was categorized moderate.
The Development of 3D Professional Pageflip-based Pregnancy Care E-Module Shovrotul Khoiriyah, Ely; Sumaryanto Florentinus, Totok; Yuniastuti, Ari
Innovative Journal of Curriculum and Educational Technology Vol 9 No 2 (2020): November 2020
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ijcet.v9i2.39919

Abstract

Midwifery education has an important role in producing competent and professional midwives. Competent and professional midwife staff starts from a quality learning process. This study aimed to develop a valid and reliable 3D Pageflip Professional pregnancy care e-module. The type of research was Research and Development (R&D) research. The data collection techniques use primary data from the validation of experts (media expert and content expert). The results of this study indicated that media expert review got an average score of 3.77 (good criterion), content expert got an average score of 4.15 (good criterion) and the pregnancy care lecturer evaluation got an average score of 4.14 (good criterion). In addition, it stated that 3D Pageflip Professional pregnancy care e-module was good and deserved to be tested in the learning process. 3D Pageflip Professional pregnancy care e-module developed as an alternative to assist midwifery students in overcoming learning difficulties. Implications this article are giving the curriculum knowledge focused on learning innovations. The application of e-pregnancy care modules was easy to learn and practically accessible anywhere. To be development and innovative teaching content of education midwife and source study midwifery student so as to increase motivation and learning outcome.
"Gizi COVID-19 Bagi Remaja" Application as A COVID-19 Prevention Rahayu, Sri Ratna; Sulistiani, Duwi; Yuniastuti, Ari; Merzistya, Aufiena Nur Ayu
KEMAS: Jurnal Kesehatan Masyarakat Vol 17, No 1 (2021)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v17i1.26843

Abstract

Adolescents are a vulnerable group in fulfilling nutrition for body defence as an effort to prevent COVID-19. Nutrition education is needed for adolescents to increase their knowledge of nutrition consumption. One of the models to improve nutrition knowledge used the Android-based smartphone nutrition application model. This research aimed to design and develop a nutrition android application model to increase adolescents' nutritional knowledge in the prevention of COVID-19. The method used Research & Development with four stages: the analysis stage, the design stage, the development stage, and the testing stage. This research produced the "Gizi COVID-19 Bagi Remaja" as a nutrition application android-based with 3 main menus, namely BMI and calories checking, nutrition info, and COVID-19 info.  The N-Grain test results show that this application effectively increases nutritional knowledge in 10 high school-adolescents (N-Grain=88.21%). The Android-based “Gizi COVID-19 Remaja” application is expected to be a comprehensive media for adolescents nutrition education during the COVID-19 pandemic in Indonesia to prevent the transmission of COVID-19.
Qualitative Study of Supporting Factors for Integrated Health Post Cadre Participation in Promotion of Local Natural Substance as Appetite Enhancer Supplement Abdurrahman Ali, Nur Aini; Yuniastuti, Ari; Handayani, Kasmini
Public Health Perspective Journal Artikel Inpres December 2021
Publisher : Universitas Negeri Semarang

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Abstract

The problem of malnutrition and severe malnutrition among toddlers in Bima regency remains very high. Thus Cadres Integrated Health Post (Posyandu) participated in promotion of local natural substances as an appetite enhancer supplement to prevent malnutrition efforts of toddlers. The purpose of this research was to qualitatively analyze the factors supporting the participation of Integrated Health Post (Posyandu) cadres in promoting substances as an appetite enhancer supplement. The study employed a qualitative approach with a phenomenological design. The focus of the study was to know in depth about the supporting factors for the participation of Integrated Health Post (Posyandu) cadres in promoting local natural substances as an appetite enhancer supplement. The determination of information using purposive and snowball techniques. Data collection techniques by means of interviews, observation and documentation. The data validity technique used source triangulation, technique triangulation, time triangulation. The data analysis technique uses miles and huberman models. The results showed that the supporting factors for the participation of Integrated Health Post cadres in promoting substances as an appetite enhancer supplement consisted of 1) Predisposing factors : knowledge of cadres about local natural substances as an appetite enhancer supplement and basic knowledge of plant, positive attitudes, culture (traditions and beliefs); 2) Enabling factor: availability of local natural materials; 3) Reinforcing Factors: Educate Women on Various Aspects of Family Welfare (PKK) activator team and public health center officers (Puskesmas).
Potensi Antidiabetik Ekstrak Kulit Lidah Buaya Pada Tikus Hiperglikemik yang Diinduksi Aloksan Susanti, R.; Rohmah, Amalia Nor; Yuniastuti, Ari
Indonesian Journal of Mathematics and Natural Sciences Vol 44, No 1 (2021): April 2021
Publisher : Universitas Negeri Semarang

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Abstract

Hiperglikemia menyebabkan tingginya radikal bebas sehingga terjadi stres oksidatif. Pada kondisi tersebut, perlu antioksidan eksogen. Penelitian ini bertujuan untuk menganalisis pemberian ekstrak kulit lidah buaya terhadap kadar malondialdehid (MDA) dan kadar superoksid dismutase (SOD) tikus hiperglikemia yang induksi aloksan. Sebanyak 25 ekor tikus strain Wistar jantan diambil secara acak dan dibagi menjadi 5 kelompok. Kelompok pertama sebagai kelompok kontrol negatif (K-). Kelompok kedua adalah kontrol positif (K+), hanya diberi aloksan. Kelompok ketiga (KP I), keempat (KP II) dan kelima (KP III), diberi aloksan dan ekstrak kulit lidah buaya berturut-turut dosis 87,5 mg/kgBB, 175 mg/kgBB) dan 350 mg/kgBB. Aloksan sebagai inducer hiperglikemia diberikan secara Intra Peritoneal dosis 120 mg/kgBB. Setelah 4-7 hari, diberi ekstrak kulit lidah buaya secara oral selama 28 hari. Data MDA dan SOD masing-masing dianalisis secara statistik dengan uji Anova, dan dilanjutkan uji Turkey. Hasil penelitian menunjukkan perbedaan signifikan kadar MDA dan SOD antara kelompok kontrol positif dan kelompok perlakuan. Potensi ekstrak kulit lidah buaya sebagai antidiabetik, ditunjukkan dengan menurunnya kadar MDA dan meningkatnya kadar SOD tikus hiperglikemik. Dosis ekstrak kulit lidah buaya yang paling efektif adalah 350 mg/kgBB (KP III), sehingga kadar MDA dan SOD tidak berbeda nyata dengan kelompok kontrol negatifHyperglycemia causes oxidative stress by free radicals. Exogenous antioxidants are needed to offset the impact. This research would observe Aloe vera peel extract to malondialdehyde (MDA) content and superoxide dismutase (SOD) level of diabetic rat. A total of 25 male Wistar rats were taken randomly and divided into 5 groups. The first group as a negative control group (K-). The second group is positive control (K +), given alloxan only. The third (KP I), fourth (KP II) and fifth (KP III) group were given alloxan and aloe vera pell extract at a dose of 87.5mg/kgBW, 175mg/kgBW and 350mg/kgBW, respectively. Alloxan as an inducer of hyperglycemia, was given intra-peritoneally at a dose of 120mg/kgBW. After 4-7 days, the aloe vera peel extract was given orally for 28 days. MDA and SOD data were statistically analyzed with the Anova test, followed by the Turkey test. The results showed a significant difference in MDA and SOD levels between the positive control group and the treatment group. The potential of aloe vera peel extract as an antidiabetic was shown by decreasing MDA levels and increasing levels of SOD in hyperglycemic rats. The most effective dose of aloe vera peel extract was 350mg/kgBW, it was able to reduce MDA and increase SOD until it was not significantly different from the negative control group.
The Development of Guided Inquiry-Based Students’ Worksheet in Cell Material for Senior High School Students Isnaeni, Lili Astuti; Yuniastuti, Ari; Susanti, R
Journal of Biology Education Vol 6 No 2 (2017)
Publisher : FMIPA UNNES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jbe.v6i2.19313

Abstract

This research was aimed to develop guided inquiry-based students’ worksheet in cell materials forstudents in senior high school. It has the characteristics of valid, readable, and executable. This researchwas a Research and Development (R&D) type. The validity of worksheet was valued by validator andanalyzed using percentage description. The readability of worksheets can be obtained by small scaled tryout to 20 students taken by using purposive random sampling. The executability of worksheets wasobtained by bigger scale try out to 32 students. The result of the research showed that the guided inquirybasedstudents’ worksheets had characteristics of: 1) cell titled worksheets with its observation; 2) theactivities based on syntax model of guided inquiry learning; 3) the material is related to real example; 4)the illustration picture in worksheets was real and 5) the display of worksheet in full color. The averagepercentage of validity to the worksheet was 83.06%. The percentage score of the worksheet was 85.31%with executability of 93.18%. Based on the results, it can be concluded that this worksheet has severalcharacteristics and valid category to be used. It also had good readability and executability to thestudents.
Analisis Minat Keikutsertaan Siswa dalam Bimbingan Belajar dan Implikasinya pada Hasil Belajar Biologi di SMA Umam, Syaiful Ishlahul; Alimah, Siti; Yuniastuti, Ari
Journal of Biology Education Vol 6 No 3 (2017)
Publisher : FMIPA UNNES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jbe.v6i3.21084

Abstract

Interest determines the yield. Higher learning interests can improve learning outcomes. This study aims to analyze the interest of students in participate the guidance of learning and its implications on the results of biology learning in SMAN 1 Semarang. The methodology research uses mixmethod with sequential exploration strategy. The research was conducted in the field using four methods, namely observation, interview, documentation, and questionnaire. Data were obtained in the form of description of student interest and student interest score. Furthermore, compared with the final exam results of students. Data were analyzed by correlation, regression and t-test which then explained. The results showed that 70% of students interested to participate the guidance of learning and based on linear regression analysis there is a contribution of student interest on the results of biological studies with r2 = 0.87 (α = 0.003). Pearson product moment correlation analysis obtained coefficient value 0.295 with significance 0.003 indicates that there is a positive relationship between interest with biology learning result. Based on the independent test ttest shows tvalue = 5.12 ≥ ttable = 2.32 (α = 0.00; n = 100). Based on the results of research and discussion can be concluded that some students are interested in participate the guidance of biology learning. Students' interest in learning outcomes has a positive relationship with low criteria and influences biological learning outcomes. There are differences in biology learning outcomes of students who participate the guidance of learning and not participate in tutoring.
The Relationship between Nutritional Status and Learning Pattern with Learning Outcomes of Biology Student of Universitas Negeri Semarang Nadhifah, Shiliya Lana; Yuniastuti, Ari; Pukan, Krispinus Kedati
Journal of Biology Education Vol 7 No 1 (2018): April 2018
Publisher : FMIPA UNNES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jbe.v7i1.21709

Abstract

One of the indicators to measure college students’ achievement is Grade Point Average (GPA). Moreover, nutritional status and learning pattern also influence the learning outcomes. This study aimed to analyze the relationship between nutritional status and learning pattern with learning outcomes of Biology student of Universitas Negeri Semarang. The research was a mixed method research design particularly sequential explanatory strategy.The population of the research were students majoring in biology class registered as college students in 2012, 2013, 2014, 2015 and 2016. The sampling technique in the quantitative method used proportional random sampling while purposive sampling was applied in the qualitative method. Students’ learning outcomes, in this case, were GPA. Four methods in the data collection were employed. They were an assessment of Body Mass Index (BMI), questionnaires, interviews, and documentation. Data were analyzed used partial correlation analysis followed by a multiple correlation and regression analysis. The results showed that there was a positive and significant relationship as many as 44.2% of nutritional status and learning pattern with learning outcomes. Thus, it was suggested that the nutritional status and learning pattern contribute positively to improve students’ learning outcomes.
Co-Authors Abdurrahman Ali, Nur Aini Abudu, Komaria Ode AD Safarina Adevia Maulidya Chikmah, Adevia Maulidya Adhisti Lutfia Hanan Adhisti Lutfia Hanan Adiba, Daniar Arof Adiba, Daniar Arof Adystia, Yusdike Aennie Widiastuti, Vinka Afniyati, Nur Afniyati, Nur Agnes Dwi Safarina Agnes Dwi Safarina Aidah, Nur Amalia, Devi Andreas Priyono Budi Prasetyo Anggit Kartikasari Anggraeni Noviasari, Nina Ani Rusilowati Anita Dyah Listyarini Arif Kurniadi Ariyanto, Andhika Arum Kartikadewi Arum Kartikadewi Arum Kartikadewi Asih Kuswardinah Asyumdah, Asyumdah Azkiyah, Nimas Catur Budi Laksono Budi, Dini Wurnaning Budu - Candrawan, Roni Prasetyo Chatila Maharani Darmayanti, Mey Linda Devi Dwi Jayanti Dewi Mustikaningtyas Dina Nur Anggraini Ningrum Dinda Fuji Islamiyanti Dyah Rini Indriyanti Eko Farida Elissa, Intan Ayu Ell Khaq, Arrina Ely Rudyatmi, Ely Enni Suwarsi Rahayu Eunike Raffy Rustiana Evi Widowati F. Putut Martin HB Farida, Eko Faridho, Fikrifar Rizki Fathnin, Fildza Huwaina Fatiah, Nirmala Al Faza Khilwan Amna, Faza Khilwan Feri Dwi Agustina Feri Dwi Agustina Fidia Fibriana Fitri Arum Sasi Fitri Arum Sasi, Fitri Arum Halimah, Khori Handayani, Kasmini Hidayah, Arifatul Hidayah, Salis Nur I Wayan Suardana Ibnul Mubarok Ibnul Mubarok Indah Hartati Indriani, Betty Innayah, Nurul Intan Zainafree, Intan Irawan Yusuf Irawan Yusuf Irwan Irwan Isnaeni, Lili Astuti Isnaeni, Lili Astuti Isti Hidayah Isti Mulyawati Istianah Istianah Istiqomah Dwi Andari, Istiqomah Dwi Istiqomah, Annisa Aulia Jiwanjaya, Yoga Juwita, Fitra Kamal Agus Efendi Kamala Nuriyah Kamilatussainah Kamilatussainah Kamisih, Kamisih Karomika, Ati Kasimi, Oktia Woro Khikmatul Maula, Lia Kirana Rannoe Tirta Kirana Rannoe Tirta Krispinus Kedati Pukan Lala, Salsabila Kinaya Pranindita Laraswati, Vivi Anggraeni lathifah, Ummu Lindasari, Pamela Lisdiana Lisdiana Lisdiana Lucita, Fifty K. Lyndasari, Pamela Mahalul Azam Martien Herna Susanti Mayang Siwi Dewayanti, Mayang Siwi Merzistya, Aufiena Nur Ayu Mohamad Endy Y Yulianto Muchamad Dafip Muchamad Dafip Muh Nasrum Massi Muh. Nasrum Massi Muslimah Muslimah Nabila Azzahra Luthfiah Nabila Azzahra Luthfiah Nadhifah, Shiliya Lana Nadhifah, Shiliya Lana Naufalia Riz Asmara, Qeyza Nbaia, Sara M Mohamed Negarani, Eryca Nur Bela Negarani, Eryca Nur Bela Niken Subekti Ning Setiati Nirmala Al Fatiah Nirmala Al Fatiah Noor Aini Habibah Noor Hidayah Noor Hidayah Nugrahanigsih WH Nugrahaningsih Nugrahaningsih Nugrahaningsih W H Nugrahaningsih WH Nugrahaningsih WH Nugrahaningsih WH, Nugrahaningsih Nugrahaningsih, WH Nur Kusuma Dewi Nur Rahayu Utami Nurussalma, Syafina Octarini, Dewi Oktia Woro Oktia Woro Kasmini H Oktia Woro Kasmini Handayani Parmin - Pramesti Dewi Pramusinta, Linda Prasetyowati, Tri Ari Priyantini Widiyaningrum Puspita Diana Arumawati Putri, Siti Rafika R Susanti R Susanti R Susanti R Susanti R Susanti R Susanti R Susanti R, Rahmatika Saputri Rahardjo, Bambang Budi Rahayu, Rr. Sri Ratna Rahmatih, Aisa Nikmah Rahmatih, Aisa Nikmah Ramasamy, Sujatha Ratna Rahayu, Sri Ratna Rahayu, Sri Resti Fitriati Retno Sri Iswari Retno Sri Iswari Retnoningsih, Heriani Rochly, Revinta Nur Aulia Rofika, Ana Rohmah, Amalia Nor Rr. Sri Ratna Rahayu Sa’adah, Siti Rofiatus Saiful Ridlo Satriani Satriani Sekar Arum, Vriska Roro Setyoko Setyoko Sholeha, Siti Sholikah, Anik Sholikah Shovrotul Khoiriyah, Ely Sigit Saptono Siti Alimah Siti Alimah Siti Baitul Mukarromah Siti Isnaeni SITI MAHMUDAH Siti, Putri Rafika Sowwam, Muhammad Sri Mulyani Endang Susilowati, Sri Mulyani Endang Sri Ratna Rahayu, Rr Sri Sukaesih Sugianto Sulasfiana Alfi Raida, Sulasfiana Alfi Sulistiani, Duwi Sulistyawati, Anita Sumarti Sumarti Suryo Pratikwo Suyadi Suyadi Swasty, Swasty Syarifah, Aidah Nur Talitha Widiatningrum Totok Sumaryanto Florentinus, Totok Sumaryanto Tyas Agung Pribadi Umam, Syaiful Ishlahul Utami, Hanna Dewi Utami, Hanna Dewi Vilda Ana Veria Setyawati Vilda Ana Veria Setyawati Vilda Ana Veria Setyawati Vilda Ana Veria Setyawati Virtanti, Uji Wahyuningtyas, Arini Tri Wan Jasimah Bt Wan Mohamed Radzi, Che Widya Hary Cahyati Wiwi Isnaeni Woro K H, Oktia Wulan Christijanti Yanti, Erny Yuni Yanuarita Tursinawati Yanuarita Tursinawati Yanuarita Tursinawati Yanuarita Tursinawati Yuni Wijayanti yuniarti, christina ary Yusdike Adystia Zaenafree, Intan Zunikhah Zunikhah Zunikhah Zunikhah