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All Journal Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Damianus Journal of Medicine Journal of Agromedicine and Medical Sciences Majalah Kedokteran Sriwijaya Molecular and Cellular Biomedical Sciences (MCBS) Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Indonesian Journal of Obstetrics & Gynecology Science Jurnal Penelitian dan Pengembangan Pelayanan Kesehatan Jurnal Dunia Kesmas Journal Health & Science : Gorontalo Journal Health and Science Community SRIWIJAYA JOURNAL OF MEDICINE Oto Rhino Laryngologica Indonesiana Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia J-Kesmas: Jurnal Kesehatan Masyarakat (Indonesian Journal of Public Health) World Nutrition Journal Best Journal (Biology Education, Sains and Technology) Sriwijaya Journal of Surgery Indonesian Journal of Global Health research International Journal Of Science, Technology & Management (IJSTM) Jurnal Cahaya Mandalika International Journal of Community Service Bioscientia Medicina : Journal of Biomedicine and Translational Research Media Publikasi Promosi Kesehatan Indonesia (MPPKI) TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora TROPHICO: Tropical Public Health Journal Indonesian Journal of Cancer Jurnal Sehat Indonesia (JUSINDO) Khidmah: Jurnal Pengabdian Kepada Masyarakat Eduvest - Journal of Universal Studies Jurnal Ilmu Kesehatan Masyarakat Jurnal Pengabdian Ilmu Kesehatan
Iche Andriyani Liberty, Iche Andriyani
Department Of Public Health And Community Medicine, Universitas Sriwijaya, Palembang
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Caustic esophageal injury in clinical settings Zuleika, Puspa; Saleh, Irsan; Murti, Krisna; Liberty, Iche Andriyani
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 1 (2023): VOLUME 53, NO. 1 JANUARY - JUNE 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i1.606

Abstract

Background: esophageal stricture is loss of esophageal lumen patency and may involve injuries after ingesting caustic substances. This systematic review aims to review clinical presentations, diagnostic modalities involved, treatments and outcomes, and complications of esophageal strictures following caustic injuries.Methods: this systematic review involves original researches conducted between 2002-2022 indexed in PubMed and EuropePMC searched using following MeSH terms: “((caustic injury) OR (caustic burn)) AND (ingestion) AND (inflammation)” following PRISMA algorithm. Biases were assessed using STROBE checklist and presented as narratives.Results: searches yielded 326 results with 16 studies included in this review. Majority of caustic ingestion and strictures involved pediatric population due to accidental ingestion. Alkali ingestion has more severe presentation. Radiological imaging, including CT and MRI, may help in determining damages involved. Degrees of damages are related with mortalities or morbidities, and dilatation may improve quality-of-life in some cases.Conclusion: pediatric patients are at risk for accidental ingestions and alkali ingestion creates more severe damage. Radiological imaging may assist in determining involvement of underlying tissues. 
CXC Motif Chemokine Receptor 2: Glimpses into the Molecular Pathogenesis of Placenta Accreta Spectrum Disorder Mirani, Putri; Lestari, Peby Maulina; Murti, Krisna; Liberty, Iche Andriyani; Kesty, Cindy; Andrina, Hana; Stevanny, Bella
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.481

Abstract

Investigation into the mechanism underlying excessive trophoblast invasion yields further strategies and insights for the diagnosis and treatment of placenta accreta spectrum disorder (PASD). We conducted a comprehensive literature review to analyze the relationship between CXCR2 expression and PASD, as well as the possibility of CXCR2 being used as a therapeutic and diagnostic biomarker for PASD. Chemokines are well-known mediators in the immune system, particularly for cell recruitment, angiogenesis, and tumor infiltration. CXCR2 is an important component of the immune system, particularly in neutrophils. One of the CXCR2 ligands, IL-8, has also been found to be expressed in the decidua and trophoblasts of humans and to promote autocrine or paracrine trophoblast migration and invasion. The potential role of CXCR2 in trophoblast invasion in PASD provides researchers with a glimpse into the molecular pathogenesis of PASD.CXC Motif Chemokine Receptor 2: Sekilas tentang Patogenesis Molekuler Gangguan Spektrum Plasenta AkretaAbstrakInvestigasi mekanisme invasi berlebihan trofoblas pada gangguan Spektrum Plasenta Akreta (SPA) akan memberikan lebih banyak strategi dan ide untuk diagnosis dan pengobatan. Kami melakukan tinjauan literatur yang komprehensif untuk menganalisis hubungan antara ekspresi CXCR2 dan SPA serta potensi CXCR2 sebagai penanda terapeutik dan diagnostik untuk SPA. Kemokin berperan sebagai mediator dalam sistem imun karena perannya dalam perekrutan sel, angiogenesis, dan infiltrasi tumor. CXCR2 mempengaruhi sistem imun, terutama pada neutrofil. Salah satu ligan CXCR2, IL-8, juga telah ditemukan diekspresikan dalam desidua dan trofoblas manusia serta untuk mempromosikan migrasi dan invasi trofoblas autokrin atau parakrin. Peran CXCR2 dalam invasi trofoblas pada SPA memungkinkan para peneliti untuk melihat sekilas patogenesis molekuler SPA.Kata kunci: penanda; CXCR2; plasenta akreta
Reliability of Using the Scabies Detection Form (DESKAB) in Islamic Boarding Schools Prasasty, Gita Dwi; Anwar, Chairil; Hafy, Zen; Liberty, Iche Andriyani; Argentina, Fiva; Aryani, Inda Astri
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.44810

Abstract

Scabies is an infectious skin disease caused by the Sarcoptes scabiei. This mite infestations not only cause skin damage, but can develop into local, even systemic skin infections. Therefore, instruments are needed that help early detection of scabies, especially through diagnosis in communities such as Islamic boarding schools. This study aimed to analyze the reliability of the scabies detection form (DESKAB) between Madrasah Aliyah female student rater and dermatovenerologist rater. Based on the results of the examination and Cohen's kappa test, a coefficient of 0.84 was obtained, which means that the level of reliability of the DESKAB form is strong, and a p value of 0.019 means that there is agreement in the perception of the diagnosis of scabies by the two raters. The DESKAB form can be recommended as an early detection instrument for non-medical personnel before being confirmed by medical personnel Keywords: DESKAB; diagnosis; non-medic; scabies
Comparative Test of Reconstruction with the Modified Arthrodesis Metallic and Cement (MAMC) Technique and the Juvara Technique in Resisting Axial Compression After Distal Femur Resection Septiandani, Randy Rakhmat; Primadika Rubiansyah; Iche Andriyani Liberty
Sriwijaya Journal of Surgery Vol. 7 No. 1 (2024): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v7i1.98

Abstract

Background: Limb salvage surgery (LSS) is a crucial treatment for malignancies, which mostly affects the distal femur and proximal tibia. LSS encompasses biological and non-biological reconstructions, including megaprosthesis. However, limited access to megaprosthesis in developing countries has led to alternative methods like arthrodesis such as modified arthrodesis with metal and cement (MAMC). LSS may lead to complications, requiring careful technique and implant selection but none of them conduct research about mechanical test. This research was comparing the effectiveness of techniques like MAMC with Juvara, in mechanical axial loading perspective. Methods: In this true experimental study, conducted at the Metallurgy Laboratory of the Faculty of Engineering, Universitas Sriwijaya, femur and tibia bones from cattle were used. Five samples of each variable were used based on the purposive sampling method. The research focused on variables like deformity angle and yield point which assessed using X ray. Bone constructs underwent various fixation techniques, including MAMC and Juvara. Testing involved axial pressure on the femur head using a mechanical press machine. Statistical analysis compared implant angulation after compression between Juvara and MAMC techniques under 30 kg and 60 kg loads, ultimately measuring the yield point. Results: All five samples from each group, subjected to both 30kg and 60kg pressure, exhibited no discernible changes. The average yield point for the MAMC group was notably 160KgF higher than Juvara, with respective means of 296 and 126kgF (p>0.05). Further analysis employing an Independent T-test confirmed a significant disparity between the MAMC and Juvara techniques concerning the yield point with a p-value of <0.001. Conclusion: Both the MAMC and Juvara techniques in this study effectively supported 30 and 60-kilogram loads, demonstrating their suitability for full weight-bearing compression, with MAMC exhibiting significantly greater compression resistance compared to Juvara (p = 0.001).
Association of Vitamin D Deficiency and Diabetic Foot Ulcer Patients in Dr Mohammad Hoesin General Hospital Palembang Dahlan, Kemas; Yususf, Fahmi Jaka; Irfannuddin, Irfannuddin; Murti, Krisna; Muradi, Akhmadu; Liberty, Iche Andriyani
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.149

Abstract

Vitamin D plays a role in the healing process of diabetic foot ulcers (DFU); it can improve the immune system, regulate inflammation function, and regulate growth factors in diabetes mellitus (DM). The immunomodulatory effects of vitamin D include reduced production of IL-2, IL-6, and TNF-alpha and increased production of IL-10. It also increases the activity of antimicrobial peptides (AMP) such as cathelicidin, and it promotes the differentiation of monocytes into macrophages, phagocytosis, and the production of lysosomal enzymes. Furthermore, vitamin D stimulates growth factors including vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-β). In this study, the incidence of DM and DFU in DM patients at RSUP Dr. Mohammad Hoesin Palembang will be compared to serum vitamin D levels. This research uses quantitative methods with an analytical observational design. The Mean vitamin D serum level was 11,727 ng/mL, and there was a significant association between serum vitamin D deficiency and DFU (p-value; 0.036 < 0.05). There was a significant association between serum vitamin D deficiency and DFU occurrence (p-value; 0.036 < 0.05) in Mohammad Hoesin General Hospital Palembang. Based on the results of this study, we proposed that patients with diabetic foot ulcers should have their serum vitamin D levels checked, and that vitamin D should be given to them as part of their therapy.
Multipleks PCR Konvensional Untuk Mendeteksi Soil Transmitted Helminths (STH) Risti, Sanely; Dalilah, Dalilah; Liberty, Iche Andriyani
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 1 (2025): Juni 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i1.10978

Abstract

Soil Transmitted Helminths (STH) merupakan parasit usus yang paling umum menginfeksi manusia dan masih menjadi masalah kesehatan masyarakat di banyak negara berkembang, terutama terjadi di daerah sub tropis dan tropis termasuk Indonesia. Cacing STH yang paling umum menginfeksi manusia yaitu Ascaris lumbricoides, Trichiuris trichiura dan cacing tambang, Infeksi ini menyebabkan berbagai dampak, deteksi dini dan akurat sangat penting untuk mendukung program pengendalian dan eliminasi STH yang efektif. Seiring dengan perkembangan teknologi, metode polymerase chain reaction (PCR), khususnya multipleks PCR, mulai menarik perhatian karena dapat mendeteksi DNA beberapa spesies parasit sekaligus dalam satu reaksi. Tujuan penelitian untuk mendeskripsikan hasil penelitian terkait dengan metode Multipleks PCR Konvensional mendeteksi STH dibandingkan metode lain. Metode pada penelitian ini adalah Systematic Review dengan menggunakan metode PRISMA, basis data dicari dan mencakup Pubmed, Cochrane, Science Direct, dan Elsevier Clinicalkey
Increasing Family Awareness of COVID-19 Transmission In Vulnerable Communities Iche Andriyani Liberty; Fikri, Muhammad Zainal; Irfani, Tri Hari; Pariyana, Pariyana; Tjekyan, Suryadi
International Journal Of Community Service Vol. 1 No. 2 (2021): August 2021 (Indonesia - Malaysia)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijcs.v1i2.17

Abstract

COVID-19 cases in Indonesia are still quite high. However, community mobility continues to increase. If in a family there is a vulnerable and / or comorbid age group, it will certainly be increasingly threatened when a productive family member leaves the house but is negligent in implementing health protocols. People who live in market areas, of course, are in direct contact with high economic activities and of course also indicate high mobility. The purpose of this activity is to increase family awareness of COVID-19 transmission in vulnerable communities with comorbidities. The target audience for this community service activity is 31 people who live in the Jakabaring Main Market area of ​​Palembang City. This community service activity results in an increase in knowledge about the importance of health protocols that are carried out in a disciplined and correct manner. This health protocol is carried out in order to protect each other starting from the family and for the community, especially for vulnerable communities. Apart from home visiting activities, the construction of hand washing facilities will also be used by the surrounding community and at the same time become a symbol to remind that washing hands with soap in running water is not only an obligation of the health protocol for preventing COVID-19 but will also save many lives from various threats of other infectious diseases.
Improving the Preparedness of Housewives to Deal with the Dynamics of the COVID-19 Pandemic Situation Iche Andriyani Liberty; Indri Seta Septadina; Emma Novita; Eddy Roflin; Pariyana; Abdusallam; Syifa Inanta Mulia Nasution
International Journal Of Community Service Vol. 1 No. 3 (2021): November 2021 (Indonesia - Malaysia)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijcs.v1i3.57

Abstract

COVID-19 (Coronavirus Disease-19) caused by the SARS-CoV-2 virus is known to attack all ages. Not only adults, it can also be dangerous for the elderly and children. On the other hand, offline schools have been planned to be carried out. Therefore, it is important for parents who have school-age children to know the impacts and situations that occur during the COVID-19 pandemic. The target subjects for this community service activity are 27 people who live in the Jakabaring, Palembang. This community service activity resulted in an increase in knowledge about the dynamics of the COVID-19 pandemic situation and the importance of health protocols to protect families, especially if the children attend offline school, as well as conducting periodic visits to see the development of the consistency of people's attitudes and behavior. This community service activity is also carried out in order to increase the participation of the community in the area to become the successor of information regarding the dynamics of the COVID-19 pandemic situation and the importance of health protocols to protect families, especially if the children who will attend offline school.
Education and Supplementary Food Provision for Tuberculosis Patients at the Merdeka Health Center, Palembang City Emma, Emma Novita; Iche Andriyani Liberty; Mariana; Pariyana; Hanna Marsinta Uli; Afrida Yolanda Putri; Syafira Nofwanda
International Journal Of Community Service Vol. 1 No. 3 (2021): November 2021 (Indonesia - Malaysia)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijcs.v1i3.59

Abstract

The nutritional status of TB patients is very important because it is a simple clinical sign to see the success of TB therapy. Health education or counseling is one way to change a person's knowledge and attitudes about health and can indirectly affect nutritional status. The assessment method for community service is carried out using lecture and discussion methods. Community service will be held on November 3, 2021, at the Merdeka Health Center in Palembang. The population of this activity is TB patients and drug-taking supervisors (PMO) in the working area of the Merdeka Palembang Health Center. The number of participants is 22 people. The evaluation was carried out by conducting pre-test and post-test to assess the increase in knowledge before and after education/counseling about nutrition in TB patients. The results of community service activities showed that the provision of education significantly affected the knowledge of the nutritional status of patients (p-value <0.05) between patients before being given education and after being given education. Suggestions that can be given are the need for knowledge about the nutrition and diet of TB patients to improve their nutritional status so that treatment can be optimal.
Pengaruh Puasa Ramadhan terhadap Kadar Neuropeptida Y pada Remaja Obesitas dan Overweight Tanzila, Raden Ayu; Irfannuddin, Irfannuddin; Kesuma, Yudianita; Liberty, Iche Andriyani
Syifa'Medika Vol 15, No 2 (2025): Syifa Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v15i2.9609

Abstract

Obesitas pada remaja merupakan masalah kesehatan yang semakin meningkat, dengan dampak serius terhadap metabolisme dan risiko penyakit kronis. Puasa Ramadan diketahui dapat mempengaruhi pola makan dan metabolisme energi, tetapi pengaruhnya terhadap kadar Neuropeptida Y (NPY) sebagai regulator nafsu makan masih belum banyak diteliti, terutama pada remaja obesitas dan overweight di Kota Palembang. Penelitian ini merupakan studi observasional kohort yang melibatkan 80 remaja laki-laki obesitas dan overweight yang melakukan puasa dan kelompok kontrol yang tidak puasa. Pengukuran kadar NPY dilakukan sebelum dan setelah puasa Ramadan menggunakan metode ELISA, sementara nafsu makan subjektif diukur dengan kuesioner Adult Eating Behaviour Questionnaire (AEBQ). Analisis data dilakukan menggunakan uji statistik univariat dan bivariat. Hasil penelitian menunjukkan bahwa puasa Ramadan secara signifikan meningkatkan food avoidance dan menurunkan food approach pada kelompok obesitas dan overweight (p<0,05). Namun, tidak ditemukan perubahan bermakna pada kadar NPY sebelum dan setelah puasa Ramadan (p>0,05). Simpulan yang didapat adalah puasa ramadan memiliki efek signifikan terhadap pola nafsu makan subjektif pada remaja obesitas dan overweight, tetapi tidak secara signifikan mempengaruhi kadar NPY. Temuan ini menunjukkan bahwa puasa Ramadan dapat menjadi intervensi awal yang baik dalam mengubah kebiasaan makan, meskipun mekanisme molekuler yang mendasari efek ini memerlukan penelitian lebih lanjut.
Co-Authors ., Mariana Abdusallam Abdussalam Abdussalam Achmad Ridwan Adrina Esther Liaw Afrida Yolanda Putri Ahmad, Zen Aldi Alfian Alisha Milenia Utami Ananda, Nadiya Andrina, Hana Anwar, Chairil Ardesy Melizah Kurniati Ardesy Melizah Kurniati Ardesy Melizah Kurniati Argentina, Fiva aryani, Inda astri Bahrun Indawan kasim Chairil Anwar Chairil Anwar Dahlan, Kemas Dalilah Dalilah Dewi Rosariah Ayu Dwi Handayani Dwi Lisa Nuraini Eddy Roflin Eddy Roflin Eka Febri Zulissetiana Ellysa Carolinna Elvi Sunarsih Emma Novita Emma, Emma Novita Fachmi Idris Faustina, Corinna Fifa Argentina Fitriani, Hidiyati Gita Dwi Prasasty Hamzah Hasyim Hanna Marsinta Uli Hari Kusnanto Josef Hertanti Indah Lestari, Hertanti Indah Hu, Owen Indri Seta Septadina Irfannuddin Irfannuddin Irma Yunita Puspayani Irsan Irsan Jasmine Rana Sahirah Jihan Natra Shafira Jihan Natra Shafira Kamaluddin, Muhammad Totong Kesty, Cindy Kevin.S Kirana, Junneka Sarah Krisna Murti Krisna Murti Litania Leona Hidayat Lubis, Fadhyl Zuhry Lukman Waris M. Ammar Luthfi Kurniawan M. Farhan Fadhillah Machlery.AP Mariana Mariana Mariana Mariatul Fadilah Marta Hendry, Marta Maruf Agung Muhammad Amin Muhammad Aziz Muhammad Aziz Muhammad Aziz Muhammad Aziz Muhammad Farhan Muhammad Irsan Saleh Muhammad Zainal Fikri Mulawan Umar Muradi, Akhmadu Nani Sari Murni Neubrina Raesuky Sukamto Novita, Emma Novrikasari Novrikasari, Novrikasari Nugraha Juliyanda Nur Alam Fajar Nur Alam Fajar Nurdin, Nugi Nurliyantika, Rizka Oktariana, Desi Pariyana Pariyana Pariyana Pariyana Pariyana Pariyana pariyana, Pariyana Peby Maulina Lestari, Peby Maulina Phey Liana Plorinda, Vanesha Pratama, Benny Putra Primadika Rubiansyah Pulungan, Rafiah Maharani Puspa Zuleika, Puspa Putri Mirani Qodir, Nur Radiyati Umi Partan, Radiyati Umi Rasyid, Riana Sari Puspita Ratu Ayu Dewi Sartika Ririn Puspita Risti, Sanely Rizal Zainal Rose Malfiana Salutondok, Welly Saputra, Ricky Sari, Sagita Darma Septiandani, Randy Rakhmat Stevanny, Bella Subandrate Sudarto Sudarto Susiwati, Susiwati Syafira Nofwanda Syahranni, Dhanya Syakurah, Rizma Adila Syarif Husin Syarif Husin Syarif Husin Syarif Husin Syauki Ikhsan, Diyaz Syifa Inanta Mulia Nasution Tanzila, Raden Ayu Tjekyan, Suryadi Tri Hari Irfani, Tri Hari Tungki Pratama Umar Utama, Meria Utami, Anissa Citra Utari, Sri Yuanita Windusari Yuanita Windusari Yudhie Tanta Yudianita Kesuma, Yudianita Yulia Farida Yahya Yusnilasari Yusnilasari Yususf, Fahmi Jaka Zen Hafy Zulkarnain, Mohamad