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All Journal Biospecies Jurnal Kedokteran Brawijaya JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) BERITA BIOLOGI The Indonesian Biomedical Journal Lantanida Journal Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Kesehatan Komunitas Window of Health : Jurnal Kesehatan Indonesian Journal of Medicine Jambura Journal of Health Sciences and Research Journal Health & Science : Gorontalo Journal Health and Science Community Jurnal Kesehatan Poltekita : Jurnal Ilmu Kesehatan Jurnal Keperawatan Priority Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Prima Medika Sains An-Nadaa: Jurnal Kesehatan Masyarakat AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Jurnal Inovasi Pendidikan dan Sains Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K) Jurnal Ilmiah METADATA Eureka Herba Indonesia Jurnal Kesehatan Tambusai MAHESA : Malahayati Health Student Journal Journal of Multidisciplinary Applied Natural Science Interdisciplinary Social Studies Jurnal EduHealth Journal of Current Health Sciences International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Jurnal Locus Penelitian dan Pengabdian Jurnal Sains dan Teknologi Buletin Kedokteran dan Kesehatan Prima Pharmaceutical Sciences and Research (PSR) International Journal of Health and Pharmaceutical (IJHP) International Journal of Science and Environment Journal of Pharmaceutical and Sciences. Blantika : Multidisciplinary Journal Malahayati International Journal of Nursing and Health Science

Chiuman, Linda

Universitas Prima Indonesia

Author-ID : 1391724

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Analisis Akar Masalah dan Waktu Tunggu Pelayanan Obat di Instalasi Farmasi Rawat Jalan Pinem, Sabriela Br; Ginting, Chrismis Novalinda; Chiuman, Linda
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 8 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i8.4594

Waktu tunggu pelayanan farmasi merupakan indikator penting dalam penilaian mutu pelayanan kesehatan di rumah sakit. Penelitian ini bertujuan menganalisis akar masalah dan waktu tunggu yang dibutuhkan untuk mendapatkan obat di instalasi farmasi rawat jalan RSU Royal Prima Medan. Metode penelitian menggunakan pendekatan deskriptif kualitatif dengan teknik wawancara mendalam kepada 5 informan manajemen dan observasi terhadap 50 pasien rawat jalan. Analisis data dilakukan melalui reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan akar masalah utama meliputi kurangnya SDM di instalasi farmasi, kelengkapan berkas pasien yang belum terpenuhi, ketersediaan obat yang terbatas, penggunaan sistem resep elektronik dan manual secara bersamaan, banyaknya resep di luar formularium nasional, tingginya permintaan obat racikan, dan kesulitan membaca tulisan dokter. Waktu tunggu rata-rata untuk obat non racikan adalah 24,8 menit dan obat racikan 49,44 menit, yang masih sesuai dengan Standar Pelayanan Minimal (SPM). Meskipun demikian, terdapat 8 dari 50 pasien yang mengalami waktu tunggu melebihi SPM. Penelitian ini memberikan kontribusi penting dalam identifikasi faktor-faktor yang mempengaruhi efisiensi pelayanan farmasi dan dapat menjadi dasar pengembangan strategi perbaikan sistem pelayanan.

Effectiveness Test of Ethanol Extract of Red Betel Leaves (Piper Crocatum Ruiz & Pav) Against Histopathological Features of The Pancreas and Blood Sugar Levels of Alloxan-Induced Male Mice (Mus Musculus L) Sembiring, Mahral Effendi; Nasution, Ali Napiah; Chiuman, Linda
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Diabetes Mellitus induces hyperglycemia. Low insulin production causes insulin resistance and altered protein, fat, and carbohydrate metabolism. Much research has shown that traditional herbal treatments can treat diabetes. Diabetes increases free radical production. Secondary metabolic plants include antioxidants that treat extreme illnesses like diabetes. This study examines the efficacy of ethanol extract from red betel leaves (EERBL) in lowering blood glucose levels in vivo, the optimal dose, secondary metabolite content based on phytochemical screening, and alloxan-induced pancreatic hyperglycemia histopathology. Mouse. Six 20-30 gram groups of mice were treated. Group III got 0.65 mg/kgBW glibenclamide, and Groups IV, V, and VI received oral gavage EERBL 100, 300, and 500 mg/kgBW. Group I was in standard control without alloxan, and Group II was in alloxan control. Hyperglycemic mice received 150 mg/kg BW intraperitoneal alloxan. Red betel is 96% ethanol-macerated. Oral red betel leaf extract was given for 21 days to monitor blood glucose and pancreatic function. Splitting red betel leaves to male mice significantly altered blood glucose and pancreatic histology. Red betel goes low cuts close and pancreatic histology by 58.4%. Blood glucose readings were Kruskal-Wallis significant at 0.004 or 0.05. Red betel leaf extract reduced blood glucose and enhanced pancreatic histology in male mice.

Hypolipidemic and Hypoglycemic Potentials of Garlic Extract in High-Fat Diet and Streptozotocin-Induced Wistar Rats Lie, Veronica; Girsang, Ermi; Chiuman, Linda; Puspita, Sunny
Jurnal Kesehatan Vol 16 No 2 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i2.5003

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels and often associated with hypercholesterolemia. Garlic (Allium sativum Linn.), rich in bioactive compounds such as allicin, saponins, and flavonoids, has been widely reported to possess lipid- and glucose-lowering properties. This study aimed to evaluate the hypolipidemic and hypoglycemic effects of garlic extract in Wistar rats subjected to a high-fat diet and streptozotocin (STZ) induction. A laboratory experimental design with a post-test-only control group was employed. For cholesterol assessment, hypercholesterolemic rats were administered garlic extract at doses of 0.05, 0.10, and 0.20g/head/day, while diabetic rats induced with STZ received doses of 100, 250, and 500 mg/kg body weight per day, with corresponding control groups. Garlic extract significantly reduced mean cholesterol levels in a dose-dependent manner (130.60mg/dL, 121.80mg/dL, and 112.00mg/dL for 0.05, 0.10, and 0.20g/head/day, respectively). In contrast, mean blood glucose levels showed a marginal decrease with increasing doses (282.80 mg/dL, 271.20mg/dL, and 269.27mg/dL at 100, 250, and 500mg/kgBW/day, respectively). However, no statistically significant differences were observed among groups (p=0.706, one-way ANOVA). These findings suggest that garlic extract exhibits a potent cholesterol-lowering effect in hypercholesterolemic rats but has a limited impact on blood glucose reduction under the tested conditions. Further studies are warranted to determine the optimal dosage and underlying mechanisms of action.

Effectiveness of Earthworm Extract on the Lipid Profile of Diabetic Wistar Rats Suandy, Suandy; Chiuman, Linda; Halim, Angel Jonathane
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.3

Various metabolic diseases, such as diabetes mellitus, are characterized by hyperglycemia, stemming from decreased insulin action, secretion, or both. The use of chemical medicines for diabetes mellitus, especially acarbose, involves regulating the digestion and absorption of complex carbohydrates. However, acarbose may disrupt liver function, prompting exploration into alternative sources for treatment, such as earthworm extract. The purpose of this study was to identify the effectiveness of ethanol extract and coelomic fluid from earthworms (E. eugeniae) on the lipid profile of male diabetic wistar rats (R. norvegicus) in vivo. The research hypothesis is that earthworm extracts could effectively lower the lipid profile of diabetic Wistar rats. This research is experimental research with pre-test and post-test control study group design, using an in vivo method. The results of the one-way ANOVA test of HDL were p=0.441; p=0.441; p=0.000; for LDL were p=0.691; p=0.101; p=0.049; for total cholesterol were p=0.107; p=0.347; p=0.486; and for triglycerides were p=0.028; p=0.926; p=0.553 on days 0, 7, and 14, respectively. Based on the research data, both ethanol extract and a combination of ethanol extract and coelomic fluid were able to reduce lipid profile levels on the 7th and 14th days. Earthworm extract has the potential to promote repair of β cells and is anti-inflammatory which can be used to reduce lipid profile levels.

Analyzing Ethanol’s Antioxidant Extract of Pandanus Leaves through DPPH Method Hardianti, Siti; Chiuman, Linda; Ginting, Chrismis Novalinda; Adrian, Adrian
Interdisciplinary Social Studies Vol. 1 No. 5 (2022): Special Issue
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/iss.v1i5.128

Background: Aging is a natural process and no one can avoid it. The aging process is also a physiological process that will occur in all living things. This process covers all organs of the body including the skin which is one of the body tissues that directly shows the occurrence of the aging process Aim: This research aims to analyze ethanol’s antioxidant extract of pandanus leaves through DPPH method. Method: This type of research is using experimental research designs to determine the antioxidant activity affected by time, and temperature with the DPPH method, a formulation of the effects of the ethanol extract of fragrant pandan leaves (Pandanus amaryllifous Roxb). Findings: It has active antioxidant activity and IC50 extract of fragrant pandan ethanol on the 5th day with a temperature of 50° C and on the 3rd day with a temperature of 35° C which is the best antioxidant activity.

- EFEKTIVITAS PRP TERHADAP PERUBAHAN PROFIL LIPID DARAH TIKUS PUTIH JANTAN (Rattus Norvegicus) DIABETES MELITUS YANG DI INDUKSI STREPTOZOTOCIN: EFEKTIVITAS PRP TERHADAP PERUBAHAN PROFIL LIPID DARAH TIKUS PUTIH JANTAN (Rattus Norvegicus) DIABETES MELITUS YANG DI INDUKSI STREPTOZOTOCIN Simarmata, Hans Pangestu; Saragih, Reyini Namora L.; Pasaribu, Jelita Pebriani; Sitorus, Josua Panangian; Chiuman, Linda; Janice, Janice
Biospecies Vol. 14 No. 1 (2021): Januari 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11252

Diabetes mellitus is a disease problem in Indonesia due to the inability of the pancreas to produce insulin so the body's metabolic processes are disrupted. Platelet Rich Plasma is widely known to be a treatment in various fields of medicine because it contains many growth factors (GFs) which are useful for triggering growth, tissue, and cell regeneration. This study was conducted to determine the effectiveness of PRP at doses of 0.5, 1.0, and 1.5 ml/kg BW for improving lipid profiles. This study used an experimental method where PRP was made twice centrifugation, then divided into each treatment, each group was given twice a week for three weeks. The Shapiro-Wilk test was used for normally distributed data followed by the Kruskal-Wallis test followed by the analysis Mann-Whitney with a significant value of P <0.05, that is, there was an effect of PRP administration on improving levels of lipid profiles. The PRP dose of 0.5 ml/kg BW gave the effect of increasing the lipid profile except for HDL levels and a higher PRP dose was required to significantly increase HDL levels compared to the control group.Â Â

Clinical Functional Profile of the Hands of Patients with Rheumatoid Arthritis at Royal Prima Hospital Medan Coray Carolyn Ruth Pardede, Eifel; Alexander, Rico; Chiuman, Linda
International Journal of Science and Environment (IJSE) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara in Colaboration with www.stie-sampit.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijse.v5i4.284

Rheumatoid arthritis (RA) is a chronic autoimmune disease that frequently causes progressive joint damage, particularly in the hands, resulting in impaired functional ability in daily activities. This study aims to describe the hand function of patients with rheumatoid arthritis based on age, gender, and family history at Royal Prima Hospital Medan. This research employed a descriptive quantitative design with a cross-sectional approach involving 55 respondents who met the inclusion criteria. Data were collected using a structured hand function questionnaire assessing right hand, left-hand, and bilateral hand function across various activities. Data analysis was conducted using univariate and bivariate descriptive methods through cross tabulation. The results showed that hand function impairment was most prominent in patients aged >40 years, who predominantly fell into the “poor” function category. Female respondents demonstrated a higher level of functional limitation compared to males. Meanwhile, a family history of RAcontributed as a predisposing factor but did not directly correlate with the severity of functional impairment. Patients with a family history tended to fall within the “moderate” category, while more severe impairment was observed among those without a family history. Older age and female gender are major factors associated with reduced hand function in RA patients, whereas family history serves as a predisposition rather than a determinant of severity.

Analysis Of Differences in Stress Levels of Nurses Working in Isolation and Non-Isolation Wards for Covid-19 In General Hospital Royal Prima Medan Stefenie; Ermi Girsang; Linda Chiuman; Sri Wahyuni Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Along with the escalating number of confirmed cases of COVID-19, it becomes a big demand for medical staff, in particular nurses, as the frontline in caring COVID-19 patients, this makes nurses’ stress levels to build up. So, this research aims to describe the factors that affect stress levels experienced by nurses during the pandemic COVID-19. The purpose of this study is to analyze the differences in stress levels of nurses working in isolation and non isolation wards for COVID 19 in General Hospital Royal Prima Medan. Type of research used in this research is quantitative research by using Cross Sectional approach. The results obtained from this research is that the majority of nurses in non isolation ward have stress levels that are still within normal limits with good performance and moderate workload, and the majority of nurses in isolation ward have a high level of stress with poor performance and a heavy workload. Workload (OR =5.21 95%CI 2.47-10.95; p=0.015), Performance (OR =2.60 95%CI 1.38-4.91; p=0.002), and Work Unit (OR =5.33 95%CI 2.65-10.75; p=0.029) significantly affect the sress level of nurses working at General Hospital Royal Prima Medan.

Effectiveness Of Incision Wound Healing Of Pandanus Amaryllifolius Roxb In Wistar Rats Putri, Muna Soraya; Girsang, Ermi; Chiuman, Linda; Ginting, Chrismis Novalinda
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

The incision is a condition of tissue discontinuity that is commonly encountered with the risk of prolonged healing time, imperfect wound healing, infection, etc. Assessment of the wound healing activity of the incision is the purpose of this research, which includes an examination of wound contraction, the thickness of collagen fibers, and the number of new blood vessels formation. In total, 25 rats will be divided into 5 test groups, each consisting of 5 rats; the control group (cream base treated), standard group (Povidone Iodine), followed by the treated group with 10%, 20%, and 30% pandan leaf extract ointment. The preliminary screening of phytochemical analysisshowed the presence of alkaloids, saponins, flavonoids, tannins, triterpenoids, and steroids and glycosides, with the total content of phenols and flavonoids from the ethanolic extract of Pandan Wangi is 20.95 GAE mg/gram extract, and 23.57 TAE mg/gram extract. Wound contraction examination result showed a significant difference between the treatment groups on day 16 and a sign the pairs of groups after being given the ointment with each concentration (p <0.05), especially in the group with 30% fragrant leaves extract and the standard group. Examination of new blood vessels showed a significant difference (p <0.05), especially with 30% of the leaves extract ointment. There was also a significant difference in collagen density in the group given pandanus ethanol ointment, especially at the 30% pandanus extract content against the group that was only given the ointment base. This research strongly suggests that the fragrant pandan leaf extract ointment is effective in healing incisional wounds and promises the potential for further studies on the pharmacological aspects.

Testing Antioxidant And Antibacterial Activity Of Andaliman Fruit (Zanthoxylum Acanthopodium Dc.) Ethanol Extract With Abts Method (2,2'-Azino-Bis(3-Ethylbenz-Thiazoline-6-Sulfonic Acid) And Minimum Resistant Concentration Agung Adha Witasa Dewana; Tan Suyono; Linda Chiuman; Sahna Ferdinand Ginting
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Antioxidants are chemical compounds that can donate one or more electrons to free radicals, so that these free radicals can be quenched. There are two sources of antioxidants, namely natural and synthetic antioxidants. Andaliman (Zanthoxylum acanthopodium DC.) is one of the many spice plants found in Toba Samosir and North Tapanuli Regencies, North Sumatra. Andaliman plants grow at an altitude of 1,500 m above sea level. Apart from North Sumatra. This research using method experimental research when collecting and processing andaliman fruit, making simplicia, making ethanol extracts and examining antioxidant activity tests using the ABTS free radical scavenging method (2,2'-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid) and antibacterial activity. using the minimum inhibitory concentration method. Testing the antioxidant activity of the ethanol extract of andaliman fruit with the ABTS method using a UV-VIS spectrophotometer with a wavelength of 734 nm. the regression equation (y = 0.4619 + 20.226) obtained an IC50 value of 64.4598 mg/mL which can be classified as a strong antioxidant activity. The results of the antibacterial activity test of the ethanol extract of the andaliman fruit showed that the extract had antibacterial activity in the moderate category at a concentration of 300 mg/ml with an inhibition zone of 10.

Co-Authors Adrian Adrian Adrian Adrian Afina, Lubna Agung Adha Witasa Dewana Akalili, Cory Cintia Alexander Simanjuntak Alexander, Rico AMALIA, TIARA Amir, Widya Pasca Andika Zayani Tambunan Anggraeni, Wenti Arif, Maria Nisaul Azah, Yunita Wannur Bagas Dwi Sanjaya Bangun, Chrismas Gideon Bangun, Primta Binarwan Halim Br Ginting, Lois Eprillia Bukit, Christin Debora Chairun, Ryeo Ramadhan Chintya Darma, Gladys Chiuman, Veranyca Claudia Tanamal Colin, Vito Coray Carolyn Ruth Pardede, Eifel Datitha Alodia Br Kaban, Karina DEWI SARTIKA Dhillon, Neha Amar Dika Suranda Dwi Puspitasari Dzil Fikri Edy Fachrial Erika Erika Ermi Girsang Fahlevy, Ridho Fazwiansyah Darlin Muniro Felix, Jesslyn Fentia, Lia Ferdinand, Sahna Fiska Maya Wardhani gan, claris cyntha deninta Ginting, Chirmis Novalinda Ginting, Chrismis Novalina Ginting, Chrismis Novalinda Girsang, Ermi Gozali, Juliana Grandis, Lexandria Gusbakti Gusbakti Rusip hafizha, Shalli Haicha Pritama, Irza Halim, Angel Jonathane Halim, Michael Handayani, Rr. Anisa Siwianti hardiansyah siregar Harmileni Hasya, Muhammad Nawal Hidayatti, Mustika Iksen, Iksen Indriani, Vidya Intan Hasibuan, Febria Nurul Ira Syaputri Irwan Irwan irza Haicha Pratama Janice Janice Kosasih, Michaela Kotsasi, Fransisca Krishna, Priyanka Kurniawan, Gracella Verren Lawrence, Christopher Leony, Catherine Levinna, Levinna Lie, Veronica Liena, Liena lister , Clarissa Lister, Gilbert Lumbantobing, Christina J. R. Esmaralda Lumbantobing, Christina J.R Esmaralda Marfitania, Taranipa Maswarni Mawarni, Evi Michael Michael MICHELLE HENDRIANI DJUANG Miranda Winda Sari Sitorus Mukti, Ade Indra Nadapdap, Thomson Nasution, Ali Napiah Nasution, Atika Rimalda Nasution, Isna Gita Amalia Novalinda, Chrismis Nurlaela, Lia Olivia Laurent Ong, Gabriella Fransisca Pardianto, Gede Pasaribu, Jelita Pebriani Patriyuni, Tri Permata Khaira, Azzuhra Pinem, Sabriela Br Puspita, Sunny Putri, Muna Soraya Rajagukguk, Samuel Joshua Hamonangan Tua Rambe, Natasya Septiana Razoki, Razoki Rizki, Kartika Sari Sagala, Agasy Gideon Admiral Sahna Ferdinand Ginting Saragih, Reyini Namora L. Sembiring, Mahral Effendi Sihombing, Bungaran Simarmata, Hans Pangestu Siti Hardianti, Siti Sitorus, Josua Panangian Soekardi, Adi Stanliko, Stanliko Stefenie Suandy, Suandy Sulistijanto, Eddy Suyono, Tan Syahputra, Hariyadi Dharmawan Tambunan, Ridhona Tan Suyono Tanamal, Claudia Tandiono, Michelle Tarigan, Elviyanti Tarigan, Setia Budi Tengku Rachmi Hidayani, Tengku Rachmi Tia Triyanti Tjendera, Mariaman Utami, Sherlinda Putri Utomo, Wilbert Waldo Varerina, Ria Br Perangin-angin Vera Estefania Kaban vera vera, vera Virgoh, Livia WAHYU WIDOWATI Wijaya, Johanna Fransiska Wijaya, Linda Leonando Winda Sari Yosefa, Stephanie Renata Yuliansyah, Jeri Yulita, Emi Yusmaini, Yusmaini Zendrato, Ronauli Muliani

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