Article Per Year (5 Year)
p-Index From 2021 - 2026
1.879
P-Index
This Author published in this journals
All Journal Microbiology Indonesia Indonesian Journal of Human Nutrition Jurnal Biosains Pascasarjana Indonesian Journal of Tropical and Infectious Disease Majalah Kulit, Karet, dan Plastik BERITA BIOLOGI Dental Journal (Majalah Kedokteran Gigi) The Indonesian Biomedical Journal Health Notions Journal of Applied Food Technology Indonesian Journal of Medicine Jurnal Respirologi Indonesia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia JPPS (Jurnal Penelitian Pendidikan Sains) JPPIPA (Jurnal Penelitian Pendidikan IPA) Majalah Biomorfologi (Biomorphology Journal) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) MAHESA : Malahayati Health Student Journal Berkala Penelitian Hayati Jurnal Pendidikan Ilmu Pengetahuan Alam (JP-IPA) Jurnal Natural Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Folia Medica Indonesiana
SOETJIPTO .
Departemen Biokimia Kedokteran, Fakultas Kedokteran, Universitas Airlangga, Surabaya
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Earth & Planetary Sciences Education Energy Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

Published : 46 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Journal of Applied Food Technology

 1 
Malonaldehyde Level of Administration Ethanol Extract of Purple Sweet Potato Var. Ayamurasaki in Doca-Salt Hypertensive Rats Rahmawati, Irma Sarita; Soetjipto, Soetjipto; Adi, Annis Catur; Aulanni’am, Aulanni’am
Journal of Applied Food Technology Vol 5, No 1 (2018)
Publisher : Dept. Food Technology, Faculty of Animal and Agricultural Sciences, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (33.323 KB)

Abstract

There is an increasing amount of evidence that oxidative stress related to hypertension can damage the function of diverse structures such as aorta. It is a well-established fact that chlorogenic acid and anthocyanine found in purple sweet potato generates bioactive compound with antihypertensive and antioxidant activities. The present study sought to investigate antioxidant activity of extract ethanol of purple sweet potato (EP) in deoxycorticosterone acetate (DOCA–salt)–induced hypertensive rats (Rattus norvegicus). The rats were orally administrated a 95% ethanol extract of purple sweet potato (var. Ayamurasaki) (EP) in a daily dose of 200 and 400 mg/kg body weight for 4 weeks. Aorta total malondialdehyde (MDA) and histopathology of aorta abdominal were examined. Aorta injury was observed in DOCA-salt hypertensive group rats compared to normotensive group rats, as aorta MDA significantly increased  (P<0.05). In contrast, treatment of DOCA-salt hypertensive rats with different dose of EP significantly reduced the total aorta MDA, as well as repair kidney damage, suppressed smooth muscle cell proliferation and lessen aorta wall thickening compared to controls. This is the first report that demonstrated blood pressure lowering and antioxidative effects of an ethanol extract of purple sweet potato, containing chlorogenic acid, in a DOCA–salt model of hypertension.
Co-Authors Abdurachman Abdurachman Adi, Ginanjar Sasmito Aksono HP., Eduardus Bimo Amin, Indah Binti Mohd Amin, Mochammad Aminuyati Anang Endaryanto Anggraeni, Zuhrotul Eka Yulis Annis Catur Adi Annisa Rizky Maulidiana Arumisore, Netty M Asnita, Asnita Aulanni'am, Aulanni'am Ayesie Natasha Zulka Bakhtiar, Arief Bakhtiar, Arief Bayu Satria Wiratama Budi Yanti Choirunisa, Latifatu Chorisma Permata Putri Nurazizah Citriana, Mirna Yunik Dachlan Y P Damba Bestari Dienanta, Savira Eddy Bagus Wasito Eddy Wasito, Eddy Elvaretta, Clarissa Ely Rahmatika Nugrahani Ely Rahmatika Nugrahani, Ely Rahmatika Era Catur Prasetya Fedik Abdul Rantam Fitria Sarnita G. Panggabean Ginanjar Sasmito Adi HAK HOTTA HANSON, J. Harianto Notopuro Hendri Susilo Hendy Hendarto Hermanto, Fery Herniyati HERNOMO ONTOSENO KUSUMOBROTO Huda, Khusnul Humairah, Ira Ida Bagus Narmada Indri Safitri Indri Safitri, Indri Juminten Saimin Juniastuti Juniastuti Katharina Merry Apriliani Khaerunnisa, Siti Kirana, Tjandra Lukitasari, Lina Lukitasari, Lina Luqman Hakim Andira M. THAMRIN HIDAYAT Machin, Abdulloh Maghfiroh, Faridatul Marcos, Imella MARIA INGE LUSIDA Maria Inge Lusida MOCHAMAD AMIN Mufiannoor, Eddy Muhammad Amin Muhammad Faizi, Muhammad Muhammad Hamdan Murbani, Indri Dwi MUSLIMIN IBRAHIM Nailufa, Yuyun Nasronudin Nasronudin Ni Made Mertaniasih Nur Rochmah, Nur Palupi, Dian Eka Roro Poernomo Boedi Setiawan Prabowo, Gwenny Ichsan Priyo Budi Purwono Putri, Hanif Rafika Qurnianingsih, Ema Raharjo Raharjo Rahmawati, Siti Irma Rantam F A Retno Handajani Ridhwan Biosia Wiratama Rini Devijanti Ridwan Ruslan, S. Eriaty N. Saifullah Saifullah Samsriyaningsih Handayani Setiobudi, Karen Delicia Setyawati, Dewi Sidarningsih Sidarningsih, Sidarningsih Sifak Indana Siti Khaerunnisa Sufiyah, Sufiyah Sulistyorini, Anik Susi Wahyuning Asih Susi Wahyuning Asih, Susi Wahyuning Suwandito Suwandito Suwandito, Suwandito Syafa'ah, Irmi Syafa’ah, Irmi TAKAKO UTSUMI Titut Harnanik Tjandrakirana Tjandrakirana Tuti Kusumaningsih Ulfa Kholili Ummah, Fithriyah Cholifatul Ummi Maimunah W Widia Wahyudi, Lindung Wasis Wasis Waskito, Langgeng Agung WULIJARNI, N. WULUARNI, N. Wungu, Citrawati Dyah Kencono Wungu, Citrawati Dyah Kencono Yasan, Yanna Debby Restifanny YOSHIHIKO YANO YOSHITAKE HAYASHI Yudhi Kurniawan Yudi Her Oktaviono, Yudi Her Yulia Ismail Yulia Sari Ismail Zuhrotul Eka Yulis Anggraeni Zulka, Ayesie Natasha