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All Journal AcTion: Aceh Nutrition Journal Media Farmasi Media Keperawatan: Politeknik Kesehatan Makassar Jurnal Comprehensive Health Care Jurnal Serambi Abdimas Jurnal Kolaboratif Sains Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Mandala of Health : A Scientific Journal Jurnal Pengabdian Pada Masyarakat Medical and Health Journal Journal of Public Health and Pharmacy Prosiding Seminar Nasional Pengabdian Kepada Masyarakat: Peduli Masyarakat International Journal of Business and Quality Research Linggamas: Jurnal Pengabdian Masyarakat
Wahyudin Wahyudin
Departemen Anatomi, Fakultas Kedokteran Universitas Jenderal Soedirman, Purwokerto,
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POTENTIAL OF PLANT-DERIVED ANTIMICROBIAL COMPOUND AGAINS MULTI-DRUG RESISTANT TUBERCULOSIS (MDR-TB): A LITERATUR REVIEW Pauzi, Rizqi Yanuar; Ihtiaringtyas, Suci; Wahyudin, Wahyudin
Medical and Health Journal Vol 3 No 2 (2024): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.3.2.10459

Abstract

Antibiotic resistance is currently a global challenge, especially in the healthcare. Tuberculosis is a disease caused by Mycobacterium tuberculosis that has developed to resistant strains against antibiotic. Multi-drug resistant tuberculosis (MDR-TB) is a Mycobacterium strain that is resistant to first-line TB drugs such as isoniazid and rifampicin. More than 10 million people suffer from TB every year, while MDR-TB sufferers in 2022 about 410,000 people. Treatment for MDR-TB patients has side effects in the form of toxicity. Plant-derived antimicrobial compounds have the potential to inhibit the growth of MDR-TB so they can be used as alternative treatments. Recent studies discuss several potential plant compounds against MDR-TB in a country. This article presents several antimicrobial compounds from various plant species from various countries against MDR-TB. The results of the study showed that around 20 compounds from various plant species had the potential to inhibit MDR-TB. These compounds can be developed further, especially by examining their side effects on the body so that they can be used as an alternative treatment for MDR-TB.
PENGETAHUAN ORANG TUA TENTANG KECACINGAN DAN PENGOBATAN TERHADAP KEJADIAN INFEKSI SOIL TRANSMITTED HELMINTH DI SDN CIBEREM KECAMATAN SUMBANG KABUPATEN BANYUMAS: A CROSS SECTIONAL STUDY Susiawan, Lieza Dwianasari; Wahyudin, Wahyudin; Sari, Octavia Permata; Pramono, Wisnu Budi; Bahiyah, Fiona Annisa
Medical and Health Journal Vol 3 No 2 (2024): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.3.2.11388

Abstract

Soil Transmitted Helminths (STH) infection is a disease caused by nematodes and often occurs among elementary school age children. One factor that can influence the occurrence of recurrent infections is parents' lack of understanding about worm treatment. Errors in treating worms can be influenced by several factors, one of which is the level of parental knowledge. To determine the relationship between the level of parental knowledge about worms and treatment on the incidence of Soil Transmitted Helminth infections at SDN Ciberem, Sumbang District, Banyumas Regency. Analytical research is an observational study with a cross-sectional design on 96 Ciberem Elementary School students using purposive sampling techniques. Data collection was carried out by questionnaires on parental knowledge and fecal examination at the FK Unsoed Parasitology Laboratory using the floating method (qualitative). Hypothesis analysis uses Fisher's Exact test. Result: The prevalence of STH infection at SDN Ciberem was 5.2% with the worm type Trichuris trichiura. The results of the Fisher's Exact statistical test showed that parental knowledge about worms (p= 0.052) did not have a significant relationship with the incidence of STH infection. The level of parental knowledge about worm treatment (p=0.033) has a significant relationship with the incidence of STH infection. Conclusion: There was no relationship between the level of parental knowledge about worms and the incidence of STH infection. There is a relationship between the level of parental knowledge about worm treatment and the incidence of STH infection.
EKSTRAK TUMBUHAN SEBAGAI AGEN ANTIMIKROBA UNTUK METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA): REVIEW Pauzi, Rizqi Yanuar; Septiya, Lia; Ihtiaringtyas, Suci; Wahyudin, Wahyudin
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12282

Abstract

Plant extracts have become an intriguing subject of research in the search for effectiveantimicrobial agents against Methicillin-Resistant Staphylococcus Aureus (MRSA), which is a global health issue due to its resistance to various antibiotics. Several studies have shown that compounds such as alkaloids and polyphenols in plants are responsible for their antimicrobial properties. Extracts from plants such as Azadirachta indica, Psidium guajava, and Rhamnus californica have demonstrated antibacterial activity against MRSA. Other research indicates that compounds like Psorothatin C from Psorothamnus fremontii are also effective against MRSA. The main challenge in managing MRSA infections is resistance to conventional antibiotics like vancomycin. Therefore, further research on plant extracts and synthetic compounds with antimicrobial activity against MRSA could provide significant contributions to the development of new therapies. Approaches involving the combination of plant extracts with conventional antibiotics also show potential in enhancing treatment effectiveness. A deep understanding of the mechanisms of action of these plant extracts is crucial for developing effective treatment strategies, and with further research, plant extracts could become an important alternative in addressing MRSA infections that are resistant to antibiotics.
Prediktor Penyakit Jantung Koroner (PJK) Melalui Pemeriksaan Profil Lipid (HDL, LDL, Trigliserid) Menggunakan Rumus Castelli Dan Indeks Aterogenik Plasma (AIP) di Desa Srowot Kecamatan Kalibagor Kabupaten Banyumas Wahyudin Wahyudin; Tirta Wardana; Rizak Tiara Yusan; Fitranto Arjadi; Kasum Kasum; Nursan Saad
Linggamas: Jurnal Pengabdian Masyarakat Vol 1 No 2 (2024): Linggamas: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.linggamas.2024.1.2.10363

Abstract

Kolesterol berkaitan erat dengan kejadian penyakit jantung koroner atau PJK. Kolesterol yang terlalu banyak di dalam pembuluh darah akan menyebabkan akumulasi plak kolesterol atau sering disebut aterosklerosis. Pemeriksaan kolesterol lengkap yang meliputi low density lipoprotein (LDL), high density lipoprotein (HDL), trigliserida, dan kolesterol total dapat memberikan gambaran atau prediktor resiko PJK dengan menggunakan rumus indeks Castelli dan Indeks aterogenik plasma (IAP). Pemeriksaan kolesterol lengkap dilaksanakan bekerja sama dengan Kader Posyandu, Bidan Desa, dan Perangkat Desa dengan jumlah responden sebanyak 48 orang yang terdiri dari 40 perempuan dan laki-laki sebanyak 8 orang. Hasil pemeriksaan menunjukkan bahwa resiko PJK dengan menggunakan indeks Castelli sebagian besar warga memiliki resiko rendah sebanyak 69% dibanding resiko sedang 27% dan resiko tinggi sebanyak 4 %. Sedangkan dengan menggunakan IAP, menunjukkan bahwa sebagian besar mengalami resiko tinggi PJK sebanyak 38%, resiko sedang 52%, dan resiko rendah hanya mencapai 10%. Kegiatan ini diharapkan menjadi bahan evaluasi bagi warga agar lebih memperhatikan pola makan yang dapat meningkatkan resiko terjadinya PJK, dengan mengurangi makanan-makanan yang mengandung kolesterol yang tinggi
Pelatihan Diagnosis Anemia Dan Thalassemia Bagi Dokter Dan Tenaga Teknis Kesehatan Di Wilayah Banyumas Lantip Rujito; Wahyu Siswandari; Wahyudin Wahyudin; Diyah Woro Dwi Lestari; Miko Ferine; Thianti Sylviningrum; Suprihatin Suprihatin; Sito Hatmoko
Linggamas: Jurnal Pengabdian Masyarakat Vol 2 No 1 (2024): Linggamas: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.linggamas.2024.2.1.12905

Abstract

Masalah kesehatan Thalassemia di Indonesia, khususnya di Banyumas, telah menjadi perhatian utama karena tingginya prevalensi dan dampak ekonomi yang signifikan. Kabupaten Banyumas, dengan angka carrier Thalassemia yang mencapai 8%, menghadapi tantangan besar dalam pencegahan penyakit ini. Artikel ini membahas pelatihan yang dilakukan untuk meningkatkan kapasitas tenaga kesehatan dalam diagnosis dan pencegahan anemia serta Thalassemia di wilayah Banyumas. Pelatihan ini diikuti oleh tenaga teknis kesehatan dari berbagai Puskesmas dan berhasil meningkatkan pengetahuan serta keterampilan peserta secara signifikan. Selain itu, pelatihan ini juga mendorong terbentuknya jaringan kolaborasi antar Puskesmas yang penting untuk keberhasilan implementasi program pencegahan di masa mendatang. Meskipun demikian, tantangan yang teridentifikasi selama pelatihan, seperti keterbatasan alat dan variasi pemahaman masyarakat, menunjukkan perlunya upaya berkelanjutan dan dukungan dari berbagai pihak. Hasil pelatihan ini menjadi langkah awal yang penting menuju pencapaian target zero Thalassemia mayor di Banyumas pada tahun 2030.
Pemeriksaan Glukosa Darah Dan Kolesterol Serta Penyuluhan Kesehatan Tentang Hiperkolesteronemia dan Komplikasi Diabetes Mellitus Pada Warga Dengan Overweight Dan Obesitas Di Desa Kalibagor, Kecamatan Kalibagor, Kabupaten Banyumas Wahyudin Wahyudin; Fitranto Arjadi; Muhamad Rifqi Setyanto; Rizqi Yanuar Pauzi; Slamet Riyanto; Nursan Saad
Linggamas: Jurnal Pengabdian Masyarakat Vol 2 No 1 (2024): Linggamas: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.linggamas.2024.2.1.12942

Abstract

Overweight dan obesitas telah menjadi masalah kesehatan global yang serius, termasuk di Indonesia. Kondisi ini tidak hanya mempengaruhi penampilan fisik, tetapi juga meningkatkan risiko berbagai penyakit kronis, seperti diabetes mellitus dan penyakit jantung. Pemeriksaan glukosa darah dan kolesterol secara berkala merupakan langkah penting dalam deteksi dini diabetes mellitus dan hiperkolesteronemia. Diabetes mellitus, suatu kondisi di mana tubuh tidak dapat memproduksi atau menggunakan insulin dengan baik, dapat menyebabkan berbagai komplikasi serius jika tidak ditangani dengan tepat, seperti kerusakan ginjal, saraf, dan penglihatan. Pengabdian masyarakat yang dilakukan yaitu pemeriksaan GDS dan kolesterol total kemudian dilanjutkan dengan penyuluhan kesehatan tentang hiperkolesteronemia dan komplikasi diabetes mellitus. Hasil pemeriksaan diperoleh sebagian besar warga yang hadir mengalami overweight dan obesitas sebanyak 70%, dan sisanya mempunyai berat badan yang normal, yang mengalami diabetes sebanyak 12%. Peningkatan kesadaran masyarakat tentang pentingnya menjaga berat badan dalam rentang normal, bersama dengan pola hidup sehat, dapat membantu menurunkan prevalensi penyakit metabolik di masa depan.
Black Garlic Supplementation and Glomerular Protection in Hyperuricemic Rats: A Study on Kidney Health Prevention Wahyudin, Wahyudin; Wahyu Pribadi, Fajar; Nawangtantrini, Gita; Riski Fatah, Muhammad; Zainuddin, Zainuddin
Journal of Public Health and Pharmacy Vol. 4 No. 3: NOVEMBER 2024
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v4i3.5496

Abstract

Introduction: Hyperuricemia is a significant risk factor for the development of chronic kidney disease. Excessive uric acid can deposit in the kidneys, triggering inflammatory reactions and oxidative stress, leading to structural damage in the glomeruli. Black garlic, with its antioxidant and bioactive compounds, has the potential to protect the kidneys from hyperuricemia-induced damage. Our objective is to evaluate the effect of black garlic supplementation on the histopathological features of glomeruli in a hyperuricemic rat model. Methods: This study was an analytical observational study using Biological Remnant Materials (BRM) from a previous study. The sample consisted of 30 male Sprague-Dawley rats divided into 5 groups: disease control, drug control (allopurinol), and 3 black garlic dose groups (240 mg/day, 480 mg/day, and 960 mg/day). Data were collected through histopathological examination of kidney tissue using the glomerular damage scoring method (0-3). Data analysis was performed using one-way ANOVA and post hoc LSD tests. Results: Black garlic demonstrated protective effects on the histopathological features of glomeruli in hyperuricemic rats. The 240 mg/day dose showed the most significant improvement in kidney health, reducing glomerular damage scores compared to the disease control group (p < 0.05). These findings suggest that black garlic can serve as a preventive agent against kidney complications caused by hyperuricemia. Conclusion: Black garlic provides protective effects on glomerular histopathology in hyperuricemic rats, with the 240 mg/day dose being the most effective. These results suggest potential use for black garlic in preventing kidney complications in hyperuricemia.
THE RELATIONSHIP BETWEEN BLOOD PRESSURE AND BLOOD SUGAR LEVELS: THE MODERATING ROLE OF AGE AND GENDER Wahyudin, Wahyudin; Pauzi, Rizqi Yanuar; Yunika, Novia; Setyanto, Muhamad Rifqi; Hidayah, Arfi Nurul
Medical and Health Journal Vol 4 No 2 (2025): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2025.4.2.14571

Abstract

This study aimed to evaluate the relationship between blood pressure and blood sugar levels, and how age and gender moderate the relationship. The study involved 105 respondents who underwent health check-ups in Banyumas Regency. Blood pressure was categorized as normal or hypertension, while blood sugar levels were divided into normal, prediabetes, and diabetes. The Chi-Square test showed a significant association between blood pressure and blood sugar levels (p < 0.05), although the strength of the association was relatively weak. Individuals with hypertension have a higher risk of developing blood sugar disorders, especially in women and individuals over 45 years old. Ordinal regression analysis showed that age and gender played an important role in influencing this association. These findings emphasize the importance of an integrated approach in screening and management of hypertension and diabetes, to prevent long-term complications such as cardiovascular disease and renal failure. The practical implications of this study can be used to design more effective public health programs
THE RELATIONSHIP BETWEEN ANTHROPOMETRIC PARAMETERS AND BODY MASS INDEX WITH BLOOD GLUCOSE LEVEL: AN ANALYTICAL STUDY Pauzi, Rizqi Yanuar; Wahyudin, Wahyudin; Nur'aini, Indah
Medical and Health Journal Vol 4 No 2 (2025): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2025.4.2.14573

Abstract

This study aims to analyze the relationship between body weight, height, body mass index (BMI), and blood glucose levels among 105 study subjects . Descriptive analysis results show that the average body weight of subjects is 64.81 kg, height is 1.62 m, and blood glucose level is 107.05 mg/dl, with significant variation in glucose levels. Scatter plots indicate that blood glucose does not have a significant relationship with body weight and height, while there is a tendency for increased blood glucose levels with increasing BMI. Correlation analysis reveals a strong positive relationship between body weight and BMI, but blood glucose does not show significant relationships with other variables. Using quantile regression, the analysis shows no significant relationship between independent variables and blood glucose at the median quantile. These findings highlight the need for further research to understand the factors influencing blood glucose levels and the importance of comprehensive assessment of anthropometric parameters.
EFFECTIVENESS OF YOGA THERAPY EDUCATION ON KNOWLEDGE AND ATTITUDES OF T2DM PATIENTS IN TAKALAR REGENCY Suardi, Suardi; Ernawati, Ernawati; Oktaviana, Dina; Alwi, Alwi; Patmawati, Patmawati; Dewiyanti, Dewiyanti; Wahyudin, Wahyudin; Zainuddin, Zainuddin; Ilham, Rosmin; Thalib, Abdul
Mandala Of Health Vol 18 No 1 (2025): Mandala of Health: A scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2025.18.1.15820

Abstract

Background: Diabetes mellitus is a chronic disease characterized by increased blood sugar levels (hyperglycemia) and glucose intolerance caused by the pancreas not producing enough insulin or the body being unable to use the insulin produced effectively. Objective: to determine the effectiveness of yoga therapy education on knowledge and attitudes in T2DM patients in Takalar Regency. Method: This research uses an experimental approach with a one-group pre-post test design. The number of respondents was 30 using the Accidental Sampling sampling method. The statistical test used is the paired sample test with ρ<0.05. Results: In this study, pre-intervention knowledge results were obtained with a mean of 5.47, and mean post-intervention knowledge increased to 8.47 with a value of ρ=0.001, while pre-intervention attitudes had a mean of 20.20, while post-intervention attitudes the mean increased to 26.83, with a value of ρ=0.001. Conclusion: there is an influence of yoga therapy education on the knowledge and attitudes of T2DM patients in Takalar Regency.
Co-Authors A Fahira Nur Ahmad Yani Alfi Muntafiah Alwi Alwi arafah, Salmah Arfi Nurul Hidayah Arfi Nurul Hidayah Bahiyah, Fiona Annisa Budi Jaya Santoso Dewiyanti, Dewiyanti Dina Oktaviana Diyah Woro Dwi Lestari Dwi Nur Indah Sari, Dwi Nur Indah Ernawati Ernawati Fajar Wahyu Pribadi Fitranto Arjadi Fitranto Arjadi Hajid Rahmadianto Mardihusodo Handini, Tri Okmawati Hartina, Hartina Hasanuddin Nuru Hasnah Mutfii Hendra Stevani Hidayah, Arfi Nurul Ichsyani, Meylida Ihtiaringtyas, Suci Indah Rahmawati Jajar Setiawan Joko Setyono Joko Setyono Kamriana Kamriana Kamriana, Kamriana Kasum Kasum Kusuma, Muhammad Nanang Himawan Laksitasari, Anindita Lantip Rujito Lily Kusumawati Burkon Meida Sofyana Miko Ferine Miko Ferine Muhamad Rifqi Setyanto Muhamad Rifqy Setyanto Muhammad Afif Muhammad Iqbal Firdaus Nafiisah Nafiisah Najmudin Nawangtantrini, Gita Nendyah Roestijawati Ning Widhi, Anriani Puspita Karunia Nining Yusnitasari Nitihapsari, Galuh Yulieta NUR'AINI, INDAH Nurachmy Sahnir Nursan Saad Octavia Permata Sari Octavia Permata Sari, Octavia Permata Patmawati Patmawati, Patmawati Pauzi, Rizqi Yanuar Qodri Santosa Rafika Zamri Rani Afifah Nur Histiyani Ratnasari Iskandar Riski Fatah, Muhammad Rismayanti Rismayanti Rizak Tiara Yusan Rizki Amelia Sinensis Rosmin Ilham Rosmin Ilham Sallazaria Hanin Prameswari Syafiqa Ardli Sarinah Basri K Sartika, Sartika Septiya, Lia Setiawan, Ferdy Setiawati Setiawati Setyanto, Muhamad Rifqi Sindhu Wisesa Siti Munfiah Sito Hatmoko Slamet Riyanto Sofro, Zaenal Muttaqien Suardi Suardi Sudarto Sudarto Sulaiman, Ibrahim Suprihatin Suprihatin Supriyati . Susiawan, Lieza Dwianasari Syamsul, Muharti Synta Haqqul Fadhilah Thalib, Abdul Thianti Sylviningrum Tiara Yusan, Rizak Tirta Wardana Viva Ratih Bening Ati Wahyu Siswandari Wisnu Budi Pramono, Wisnu Budi Wiwiek Fatchurohmah, Wiwiek Yudhi Wibowo Yudhistira Tri Wardhana Yunika, Novia Zainuddin Zainuddin Zainuddin Zainuddin Zainuddin, Zainuddin