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EDUKASI TERAPI KOMPLEMENTER DIABETES DAN HIPERTENSI PADA MASYARAKAT DESA TOSALE KABUPATEN DONGGALA Ismail, Ihwan; Yuliet; Fahrul Hardani, Muhammad; Khaerati, Khildah
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 1 No. 1 (2022): Oktober 2022
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2022.v1.i1.16110

Abstract

Diabetes melitus dan hipertensi merupakan dua penyakit degeneratif yang mayoritas masyarakat derita diera modern ini. Diabetes melitus merupakan penyakit yang ditandai peningkatan kadar glukosa darah disebabkan retensi insulin, selain bekerja merubah glukosa menjadi glikogen, retensi insulin juga dapat mengakibatkan peningkatan retensi natrium di ginjal dan mengakibatkan aktivitas sistem syaraf simpatik. Retensi natrium dan meningkatnya aktivitas sistem syaraf simpatik merupakan dua hal yang berpengaruh terhadap meningkatnya tekanan darah atau sebut hipertensi. Pengabdian ini bertujuan untuk meningkatkan pengetahuan dan pemahaman masyarakat tentang Diabetes melitus dan hipertensi dan cara penanganannya dengen terapi komplementer berbasis bahan obat tradsional yang ada disekitar masyarakat sehingga dapat meningkatkan kualitas hidup. Metode pelaksanaan pengabdian pada masyarakat ini menggunakan pendekatan pemeriksaan kesehatan meliputi penimbagan berat badan, tekanan darah dengan tensimeter elektrik, kadar gula darah dengan glokotest dan dilanjutkan dengan penyuluhan dengan memberikan edukasi berupa liaflet dan brosur serta booklet terkait terapi komplemeter berbasis bahan alam pada Diabetes melitus dan hipertensi kepada masyarakat Desa Tosale Kecamatan Banawa Selatan Kabupaten Donggala. Hasil pemeriksaan dari 50 warga Desa Tosale diperoleh 2 % (1 warga) memiliki kadar gula darah diatas 200 mg/dl yang dikategorikan dalam diabetes dan 98% (49 warga) memiliki kadar gula darah normal sedangkan pemeriksaan tenanan darah diperoleh 46% warga dengan tekanan dara normal, 28% kategori prehipertensi, 16% hipertensi stage 1 dan 10 % warga mengalami hipertensi stage 2. Kesimpulan pengabdian ini adala terdapat Meningkatnya pengetahuan dan pemahaman masyarakat tentang diabetes melitus dan hipertensi dan cara penanganannya dengen terapi komplementer bahan obat tradsional yang ada disekitar masyarakat sehingga dapat meningkatkan kualitas hidup dan Peningkatan perilaku sehat dengan penggunaan obat berbasis bahan alam
Edukasi Pengenalan Apoteker Cilik dan DAGUSIBU Pada Siswa SDN 4 di Desa Bahomoleo Kecamatan Bungku Tengah Kabupaten Morowali Ismail, Ihwan; Khaerati, Khildah; Yuliet, Yuliet; Yuyun, Yonelian
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 2 (2024): April 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v2.i2.17099

Abstract

Pharmacists are pharmaceutical graduates who have completed pharmacy education and have taken the pharmacist oath, carrying out pharmaceutical work including the manufacturing, quality control of pharmaceutical preparations, security, procurement, storage, distribution, or dispensing of drugs, drug management, prescription drug services, drug information services, as well as drug development, drug substances, and traditional medicines. Currently, the empowerment of health education programs and health services at an early age, especially at the elementary school level, has begun to develop. Children need to receive a lot of information about various professions to increase their insights and stimulate their learning spirit. Based on this, education activities of Junior Pharmacists (Apoteker Cilik) and DAGUSIBU (acronym for Obtaining, Using, Storing, and Disposing of drugs properly) were conducted for elementary school students to introduce the pharmacist profession and educate them on obtaining, using, storing, and disposing of drugs properly. The education was conducted for 5th and 6th-grade students at SDN 4 Bungku Tengah, Morowali, Central Sulawesi, involving 60 students. The method of this activity was through PowerPoint presentations, selection of speakers and materials for Junior Pharmacists and DAGUSIBU, and evaluation of education through question and answer sessions on the material. The evaluation results showed a positive outcome, namely an increase in knowledge about the pharmacist profession and proper drug DAGUSIBU.
Subchronic Toxicity Test of Purple Leaves Ethanol Extract (PLEE) on the Histopathological Picture of the Lymph of Wistar Rats and Antioxidant Activity Darmayanti; Dewi, Niluh Puspita; Mariyani; Tandi, Joni; Rachmawati, Meike; Susanto, Yuliet
Jurnal Penelitian Pendidikan IPA Vol 10 No 7 (2024): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i7.8070

Abstract

This study aims to determine the toxic effects of purple leaf ethanol extract on lymph organs at doses of 500; 2.000; and 5.000 mg/kgBB administered for 28 days and and to determine the antioxidant activity of purple leaf Graptophyllum pictum (L.) This study is an experimental study with a random group design, using 20 test animals divided into 4 groups consisting of two treatment groups, namely in the normal control group given Na-CMC 0.5% and the experimental group given PLEE (k1: dose 500 mg/kgBB, k2: dose 2.000 mg/kgBB and k3: dose 5.000 mg/kgBB hematoxylin-eosin staining (HE) using a computer-connected Motic BA210 microscope with 40X magnification in 5 fields of view and antioxidant test using DPPH method with UV-Vis Spectrophotometer at 516 nm wavelength with concentration 20, 40, 60, 80, and 100 ppm. The results showed that leaf ethanol extract was toxic at a dose of 2.000 mg/kgBB – 5.000 mg/kgBB against the diameter of lymphatic organ pulp, organ index and organ weight, there were symptoms of toxicity and purple leaf ethanol extract had strong antioxidant activity with 66.26 μg/mL.
Biochemical Serum Changes in the Liver and Kidney of Hyperuricemia Rats Exposed to Ethanolic Leaf Extract of Hantap (Sterculia coccinea Jack) Yuliet; Auliana, Rhizky S; Miranti; Rindiani, Ni Luh; Sombolinggi, Marzelany M; -, Khildah; Khaerati
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.8832

Abstract

High uric acid levels can increase oxidative stress in the kidneys causing glomerular damage and tubular ischemia. In addition, it also causes hepatocyte injury so that uncontrolled hyperuricemia will cause liver damage. This study aims to determine the effect of Hantap leaf extract (Sterculia coccinea Jack) on kidney and liver function in rat hyperuricemia. This study was a quasi-experimental study with a post-test only control group design. This study used 30 rats induced with chicken liver juice and potassium oxonate and then given Hantap leaf ethanol extract therapy at doses of 100, 200 and 400 mg/kg BW. Data on urea, creatinine, SGOT and SGPT levels were statistically tested using the ANOVA and Post-hoc Duncan tests. While data on uric acid levels used the T test and Anova. Significantly different results compared to negative controls were found in the group given Hantap leaf extract at doses of 100, 200 and 400 mg/kg BW on uric acid, creatinine, ureum, SGOT and SGPT levels. The results of the study prove that administering Hantap leaf extract can improve kidney and liver function in hyperuricemic rats.
The Effect of Adsorbents on the Quality of Refined Eel Fish (Anguilla marmorata [Q.] Gaimard) Oil as a Raw Material for Pharmaceutical Preparations Jamaluddin; Yuliet; Musnina, Wa Ode S.; Yuyun, Yonelian; Shaldan, Syahna; Malasugi, S.; Arta, Putri A.; Putri, Gina N.; Maryani, Adetya; Haq, Muhammad F.; Lakahoro, Syamsul; Firman, Nurul Awwaliyah P.; Al-Amri, Siti B.; Amelia, Sinta; Hasanuddin, Asriani; Serdiati, Novalina; Nilawati, Jusri
Jurnal Penelitian Pendidikan IPA Vol 10 No 12 (2024): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i12.9806

Abstract

Eel fish (Anguilla marmorata (Q.) Gaimard) oil is a valuable source of health-promoting unsaturated fatty acids. Adsorbent selection during the bleaching stage of fish oil purification can significantly impact the final product quality.  This study aimed to evaluate the impact of different adsorbents on the quality of refined eel fish (Anguilla marmorata (Q.) Gaimard) oil. Eel fish oil was extracted using Soxhlet extraction with diethyl ether and purified through degumming, neutralization, and bleaching stages. Various adsorbents (bentonite, magnesol XL, and zeolite) were employed at different concentrations (1% bentonite, 3% magnesol XL, and 5% & 10% zeolite activated by acid and base) to remove impurities. The refined oils were analyzed for physical, chemical, and microbiological properties. Results showed that all adsorbents effectively improved the quality of eel fish oil, meeting most International Fish Oil Standard (IFOS) and Indonesian National Standard (SNI - 8467:2018) criteria. However, density and iodine values were below the specified limits. Microbiological analysis confirmed the absence of contamination, but lead levels exceeded the permissible standard.
Development Of an Electronic Module for Antidiabetic Testing Techniques as A Guide for Pharmacy Students in Pharmacology Practicum and Research Ihwan; Yuliet; Tahir, Moh.; Ramadhan, Ahmad
Jurnal Penelitian Pendidikan IPA Vol 11 No 10 (2025): October
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i10.12760

Abstract

The era of the 4.0 revolution is a time characterized by the development of information technology. This era offers opportunities for digitalization in various fields, including higher education. One area that greatly requires information technology is research, particularly in the development of electronic modules as learning media. This study aims to develop an electronic module on antidiabetic testing techniques as a guide for practice and research. The research method used is a Research and Development design, utilizing the ADDIE approach model (Analysis, Design, Development, Implementation, and Evaluation). The module used was validated by two content and language experts, two media expert validators, and validated for feasibility by 128 respondents using a questionnaire instrument, and the effectiveness evaluation of the module was tested by 36 students from the Pharmacy Department of Tadulako University. The research results show that the validity test by two content experts rated it as feasible with an average score of 4 and a percentage of 80%, the language expert rated it as very feasible with a percentage of 88.0% and an average score of 4.4, the design expert rated it as very feasible with a percentage of 92.22% and an average score of 4.6, the feasibility assessment by students rated it as very feasible to be used as learning media with an average score of 4.05 and a percentage of 81.02%, and the effectiveness test using N-Gain was 89%. This electronic module establishes a framework for developing interactive instructional materials in scientific education, particularly relevant to pharmaceutical sciences and healthcare fields, through its systematic integration of practical simulations and pharmacological research components within the learning environment.
The Study of Drug Storage Behavior in Indonesia: A Scoping Review: Studi Perilaku Penyimpanan Obat di Indonesia: Scoping Review Richard, Tricia Andini; Hanifah, Suci; Susanto, Yuliet
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 11 No. 2 (2025): October 2025
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2025.v11.i2.17817

Abstract

Background: Poor home drug storage techniques can worsen the issue of antibiotic resistance, lower therapeutic efficacy, and raise the risk of toxicity. The purpose of this study was to use a scoping review technique to map the knowledge, attitudes, and practices of Indonesians with regard to drug storage. Home drug storage practices may be affected by Indonesians’ knowledge, attitudes, and habits regarding the storage of household pharmaceuticals using a scoping review methodology.Methods: This study uses a scoping review methodology. The study reviewed scientific literature that was obtained from the Google Scholar database, PLOS ONE, PubMed, Indonesia One Search, by using “Boolean.” Of the 615 records, twenty-six met the inclusion requirements.Results: According to the report, most Indonesian families keep up to five types of medications in their homes. Such as antibiotics, antipyretics, antiplatelet medications, anti-hypertensive medications, cough suppressants, antihistamines, and pain relievers. Misunderstanding was also present. The improper disposal of expired medications poses not only a health issue but also a safety one. Additionally, national programs have improved people’s awareness. During the period, education programs significantly improved drug use competence and education.Conclusion: Many Indonesian houses continue to store drugs improperly. The drug management staff are working on preventing the community from storing drugs inappropriately. Increasing education and educational initiatives are required. Indonesian families continue to face many drug-related problems; more education and training, particularly safety and more effective in the community, medical personnel, suitable storage facilities, and educational initiatives are required.
Co-Authors -, Khildah Abd. Rahman Razak Adisaputra, Arya Dibyo Agus Ritna Agustinus Widodo Agustinus Widodo Ahmad Ramadhan Ahmad, Iftitah Akhmad Khumaidi Al-Amri, Siti B. Alfia, Dhara Ali Djamhuri Alkaff, Firas F. Alkaff, Sylmina D. Amelia Rumi Amelia Rumi Amelia Rumi Amelia, Sinta Andi Athira Masyta Andi Atirah Masyita Andi Atirah Masyita Andi Fadya Andrya B Andrya B Apriyanti Anastasia Arisca, Windhy Nur Ariza Abu Bakar Putri Armini Syamsidi Arta, Putri A. Arwinda Alitsia Hasyim Asriani Hasanuddin Atirah Atirah Auliana, Rhizky S Bustanul Arifin Cahyani, Rezki Cornelia Ayu Putri Daniel Happy Putra Darmayanti Dermiati T Dermiati T Devi Saputri Bahman Devyayu Prabaningsih DEWI RISMAYANTI Djaleha, Helena Fransisca Dwicahya, Bambang Dwinthasari Meilinda Azhari Elin Yulinah Sukandar Elin Yulinah Sukandar Ersamukti Rahmatullah Achmad Evi Sulastri Fahrul Hardani, Muhammad Firman, Nurul Awwaliyah P. FIRMANITA DWIMURTI Fitri Anggun Solehah Hamdani, Silviana Haq, Muhammad F. Hardani, Muhammad Fakhrul Heni Purwitasari I Ketut Adnyana Ihwam Ihwan Ihwan Ihwan Ihwan Iklima Indriani, Meri Feki Inggrid Yuliana Ingrid Faustine Ismail, Ihwan Jamaluddin Jamaluddin Jamaluddin Jamaluddin Jamaluddin Jamaluddin Jamaluddin Joni Tandi Joni Tandi, Joni Jusri Nilawati Karmini Karmini khaerati Khildah Khaerati Khildah Khaerati Khildah Khaerati Khusnul Diana Khusnul Diana Kurniawan, Muh D. Lakahoro, Syamsul Lokong, Gladies Melinda Lutfiana Kusumawati Malasugi, S. Mariyani Maryani, Adetya Masyita, Andi Atirah Meike Rachmawati Mia Audina Miranti Moh. Roem Moh. Tahir Mohamad Ikram Muhamad Rinaldhi Tandah Muhammad Anggriawan Muhammad Fahrul Hardani Muhammad Sulaiman Zubair Musnina, Wa Ode S. Muthi’ah H Z Nasrah Said Nela Sharon Ni Made Susilawati Ni Wayan Swintari Nifien Mokuna Niluh Puspita Dewi, Niluh Puspita Novalina Serdiati Nur Hikmah Nur Ramadhani Nurihardiyanti Nurihardiyanti Nurwijayanti Oryza Sativa Padmawati, Retna S. Perwitasari, Dyah A. Postma, Maarten J. Putri, Gina N. R. Rokhman, Muhammad Ramadhanil Ramadhanil Rasuane Noor Rauf, Saidah Recky Patala Revina Triani Richard, Tricia Andini Rindiani, Ni Luh Rini Saputri Ririen Hardani Ririen Hardani Ririen Ririen Ririn Hardani Ritha Pratiwi Salamah, Sovia Shaldan, Syahna Shella Desiana Sitti Kholidah Sombolinggi, Marzelany M Sri Indrawati Steffi Liem Suci Hanifah Sugeng Santoso Sukmawati, Sukmawati Syaputra, Gunawan Syariful Anam Tirza Retno Kinasih Baginda Triana Riandani Djamhuri Tricia Andini Tunreng, Muh. Fadil Usman Wijaya, Berniawan Yonelian Yuyun Yusriadi Yusriadi Zulkarnain Zulkarnain