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Quality of Life and Symptoms Management in Cancer Patients with Financial Toxicity: A Systematic Review Ikhsan Sodik; Yati Afiyanti; Hanny Handiyani; Imami Nur Rachmawati
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.6253

Abstract

Cancer is a complex disease associated with a wide range of symptoms, declining quality of life, and financial toxicity (FT).To examine the quality of life and symptoms management in Cancer patients experiencing financial toxicity based on a review of published literature.A systematic review was conducted using five databases: Sage Journals, Science Direct, ProQuest, Clinical Key, and Oxford Academic from 2015-2025 years with keywords Quality of Life, Symptom Management and Cancer Patients. The quality of studies was assessed depending on the study design of the 1,050 articles found, only 11 were reviewed. Findings from 11 studies indicated that the quality of life in cancer patients is influenced by multiple factors. Financial toxicity showed a negative correlation with quality of life (r =0.23, p = 0.0057), indicating that higher levels of financial toxicity are associated with lower quality of life. Psychological symptoms such US anxiety and depression were positively associated with FT (r = 0.27, p = 0.0151; r = 0.18, p = 0.0336). High symptom burden, both physical and psychological, significantly reduced quality of life, while social support played a positive role in enhancing well-being (r = -0.17, p = 0.0412). Integrative therapies improved quality of life by 82%, and cost related health literacy was found to reduce financial toxicity (OR = 0.823, p= 0.039). Holistic interventions and attention to the financial challenges faced by cancer patients are essential for improving quality of life, particularly for those affected by financial toxicity. Effective symptom management involves the use of various tools (ESAS, HADS, FACT-G, SESI, EORTC QLQ-C30) and approaches such as palliative care, integrative therapies, symptom cluster management, acupuncture, financial support, social support, enhanced cost-related health literacy, improved psychological resilience, and identification of financial toxicity risks.The quality of life in Cancer patients is influenced by a complex interaction of factors, including financial condition, symptom management, social support, and multidisciplinary care. Enhancing health literacy—especially regarding financial aspects—with comprehensive, evidence-based, and accessible information such as insurance, medication coverage, and financial resources, is critically important.
The Interplay between Fear of Cancer Recurrence and Unmet Needs in Breast Cancer Survivors – A Systematic Review Puji Astuti; Yati Afiyanti; Riri Maria
Indonesian Journal of Global Health Research Vol. 8 No. 1 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i1.655

Abstract

Advances in early detection and treatment have improved breast cancer survival rates; However, survivors often face psychosocial challenges such as Fear of Cancer Recurrence (FCR) and unmet needs. FCR refers to anxiety or worry about cancer returning, while unmet needs represent the gap between the support required and that received—particularly in emotional and informational aspects. Understanding their interplay is vital for developing comprehensive, needs-based nursing interventions. This study aimed to systematically review the relationship between FCR and unmet needs among breast cancer survivors, focusing on prevalence, contributing factors, and their impact on quality of life and health-related behaviors such as screening adherence and healthcare utilization. A systematic search was conducted across PubMed, Scopus, and ProQuest using the keywords “fear of cancer recurrence,” “unmet needs,” and “breast cancer survivors.” Articles written in English with systematic reviews, cross-sectional, cohort, qualitative, or mixed-methods designs were included. From 1,414 identified studies, eight met inclusion criteria and were analyzed qualitatively following PRISMA guidelines. Moderate to high FCR levels were found in 50–70% of survivors, and 60–70% reported at least one unmet need, mainly emotional and informational. Higher FCR levels were strongly associated with increased unmet needs. Unmet needs mediated FCR's impact on health behaviors, leading to lower screening participation and higher unplanned healthcare use. Younger age, comorbidities, and low social support exacerbated both factors. FCR and unmet needs are interrelated psychosocial issues affecting survivors' emotional well-being and behavior. Oncology nursing should integrate structured assessments and tailored interventions to improve survivors' quality of life.
The Impact of Psychosocial Factors on Quality of Life among Young Women with Breast Cancer: A Systematic Review Yuzia Melantika; Riri Maria; Yati Afiyanti; Dewi Gayatri
Indonesian Journal of Global Health Research Vol. 8 No. 2 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i2.817

Abstract

Young women with breast cancer experience complex psychosocial challenges resulting from physical, emotional, and social changes during treatment, which significantly affect their quality of life (QoL). Objective to identify and analyze psychosocial aspects influencing the quality of life among young women with breast cancer. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Literature searches were conducted across five databases (PubMed, ScienceDirect, Scopus, Sage Journals, and Taylor & Francis) for studies published between 2015 and 2025. Inclusion criteria included young women (≤40 years) diagnosed with breast cancer, using quantitative observational designs (cross-sectional or prospective cohort). A total of 11 eligible studies from 5761 articles were included and analyzed narratively. Five major themes influencing QoL were identified: (1) psychological distress (anxiety, depression, and fear of cancer recurrence); (2) sexual dysfunction and negative body image; (3) reproductive and fertility concerns; (4) social support and partner relationships; and (5) long-term QoL decline up to five years post-diagnosis, which is improved with strong social support and adaptive coping strategies. Psychosocial factors have a significant impact on the quality of life of young women with breast cancer. A holistic nursing approach that integrates psychological, social, and family support is essential to enhance emotional well-being and improve the long-term quality of life of these patients.
The role of self-efficacy, social and economic support on the quality of life of cancer patients undergoing chemotherapy: A systematic review Maria Evarista Sugo; Yati Afiyanti; Allenidekania Allenidekania; Dewi Gayatri
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 7 (2025): Volume 8 Number 7
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i7.1479

Abstract

Background: Indonesia is currently facing a triple disease burden, including a rise in chronic illnesses such as cancer, which significantly impacts patients' quality of life. Chemotherapy affects not only physical health but also psychological, social, and spiritual well-being. Factors such as self-efficacy, social support, and economic status are believed to strongly influence the quality of life among cancer patients undergoing chemotherapy. Purpose: To examine the effects of self-efficacy, social support, and economic conditions on the quality of life of cancer patients receiving chemotherapy. Method: A systematic review was conducted by searching articles published between 2015 and 2025 across PubMed, ScienceDirect, and Scopus using relevant keywords. Studies included randomized controlled trials, cohorts, case-control, and quasi-experimental designs that explored the relationship between the selected variables and patient quality of life. Ten articles met the inclusion criteria and were analyzed. Results: From a total of 453,025 articles identified, only 10 met the eligibility criteria. Findings consistently indicate that higher self-efficacy, strong social support, and stable economic conditions are positively correlated with improved quality of life in cancer patients undergoing chemotherapy. Conclusion: Enhancing self-efficacy, providing adequate social support, and addressing economic challenges can significantly improve cancer patients’ quality of life. A holistic, integrated approach that includes psychosocial and spiritual care is essential. Nurses and healthcare professionals play a crucial role in delivering these interventions, supported by appropriate policies and education to strengthen global cancer care systems.
Effectiveness of non-pharmacological interventions in managing dyspnea among cancer patients: A systematic review Feri Atmajaya; Allenidekania Allenidekania; Yati Afiyanti; Dewi Gayatri
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 9 (2025): Volume 8 Number 9
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i9.1738

Abstract

Background: The management of dyspnea in cancer patients still faces various challenges. Non-pharmacological interventions are increasingly recognized as effective, potentially cost-effective, and effective approaches to managing this symptom. Purpose: To identify, evaluate, and analyze evidence regarding the effectiveness of non-pharmacological interventions in managing dyspnea in cancer patients. Method: This systematic review followed PRISMA guidelines and conducted a literature search across five databases (Sage Journals, PubMed, ScienceDirect, Springerlink, and Google Scholar). Inclusion criteria included English-language articles published between 2015 and 2025, with a randomized controlled trial (RCT) or cohort study design. From 59,225 articles identified, 11 studies met the inclusion criteria for analysis. Results: A total of 1,369 cancer patients were analyzed across 10 RCTs and one cohort study. Various non-pharmacological interventions proven effective in managing dyspnea include Tai Chi, aerobic exercise, Respiratory Distress Symptom Intervention (RDSI), Inspiratory Muscle Training (IMT), home-based education programs, and acupuncture. Conclusion: Non-pharmacological interventions can be an important component in the management of dyspnea in cancer patients, significantly contributing to symptom reduction and overall patient well-being.
Sexual Needs Among Patients with Cancer: A Systematic Literature Review Karundeng, Riven; Afiyanti, Yati; Waluyo, Agung
IJNP (Indonesian Journal of Nursing Practices) Vol. 9 No. 1 (2025): June
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Both cancer and its treatments have profound effects on sexuality. Sex, sexuality, and intimacy hold equal importance for cancer patients as they do for individuals without cancer. Discussions surrounding sexuality are often not viewed as urgent or essential and may even be considered taboo in certain cultural contexts. The quality-of-life issues have become secondary to the primary goal of curing cancer, with little emphasis on addressing intimacy-related problems. This study aims to identify the effective interventions for addressing the sexual needs of patients with cancer. Method: This is a systematic literature review. A thorough literature review in three data bases including PubMed, Science Direct and Sage was conducted.. The article analysis process used the PRISMA method. Results: 10 articles were reviewed that met the criteria, and the articles used randomized controlled trials, quasi-experimental studies, and cross-sectional methods. Conclusion: Cancer and its treatment can cause various physical and psychological changes that can significantly impact the patient's sexual function. The interventions that address the sexual needs of cancer patients, such as psychosexual support, sexual psychoeducation, sexual communication, and social support, are an important need for cancer patients to overcome their sexual problems, to adapt, to maintain intimacy, and to improve their quality of life. Sexual needs are an important aspect that must be addressed and managed comprehensively in the management of cancer patient care to improve their quality of life.
Psychoeducational Intervention terhadap Fungsi Seksual, Ansietas, dan Depresi Penyintas Kanker Ginekologi: Systematic Review Susiladewi, Ida Ayu Md. Vera; Afiyanti, Yati; Waluyo, Agung
Jurnal Kesehatan Vokasional Vol 9, No 4 (2024): November
Publisher : Sekolah Vokasi Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkesvo.99850

Abstract

Latar Belakang: Gangguan fungsi seksual akibat kanker ginekologi dan pengobatannya mengganggu kehudupan pasien yang mengakibatkan rendahnya kualitas hidup dan tingginya ansietas dan depresi. Psychoeducational intervention dalam rehabilitasi pasien kanker ginekologi memiliki banyak diterapkan dalam praktik perawatan pasien.Tujuan: Penelitian bertujuan untuk mengetahui efektivitas psychoeducational intervention  terhadap peningkatan fungsi seksual, ansietas, depresi dan kualitas hidup pasien dengan kanker ginekologi.Metode: Penelitian ini menggunakan metode systematic review yang dilakukan pada bulan Maret sampai dengan Juni 2024. Penulis menggunakan lima basis data artikel penelitian berbahasa Inggris. Penelitian yang memenuhi syarat dianalisis dan diekstraksi oleh dua penulis secara independen.Hasil: Sebanyak 1.157 artikel telah diidentifikasi dari lima database jurnal, yaitu Cochrane Library, PubMed, Taylor & Francis, ProQuest, dan Scopus. Dari jumlah tersebut, terdapat tujuh artikel yang memenuhi kriteria seleksi dan diikutsertakan dalam tulisan ini. Kelayakan metode penelitian dianalisis dan dikritik menggunakan instrumen Critical Appraisal Skills Programme (CASP) atau Joanna Briggs Institute (JBI). Intervensi psikoedukasi terbukti efektif dalam meningkatkan fungsi seksual serta mengurangi kecemasan dan depresi.Kesimpulan: Intervensi psikoedukasi efektif meningkatkan fungsi seksual khususnya pada domain intimasi dan gairah seksual. Intervensi psikoedukasi juga memberikan dampak positif terhadap ansietas dan depresi yang dialami perempuan dengan kanker ginekologi.
Co-Authors Achir Yani S. Hamid Achmad Fauji Ade Purnama Aditama, Dicky Agil, Hilda M Agung Waluyo Agus Nugroho, Agus Agustine Ramie Ai Aminah Allenidekania Allenidekania Andriani, Zilya Andrijono Andrijono Anita agustina Anme, Tokie Anshari, M. Apriyani Apriyani Arif Wahyu Setyo Budi Ariyanti, Kadek Yemi Aryanti Wardiyah Aryanti Wardiyah, Aryanti Arza Rufli Astrida Budiarti Atun Raudatul Ma’rifah Atun Raudotul Ma'rifah Awatiful Azza Azidin, Yustan Bahrul Ilmi Blacius Dedi Brension Relly Budiyarti, Yuliani Chandra Isabella Chrismilasari, Lucia Andi Damayanti, Shella Dean, Judith Dewi Atika Sari Dewi Gayatri Dewi Handayani Dewi Handayani Dewi Irawaty Dewi Setya Paramitha dini rahmayani Dwi Dahlia Susanti Dwi Prihatin Era Eka Riyanti Elsa Naviati Enie Novieastari Erfina Erfina Eriyono Budi Wijoyo Erni Saraswati Evi Martha Fansha Tio Anugrah Faridah , Ida Faridah, Ida Feri Atmajaya Firda Apriyanti Fitriyanti, Dwi Fitzgerald, Lisa Grace Carol Sipasulta Hana Dodik Pramiasti Handayani, Fitria Hanik Rohmah Irawati Hanny Handiyani Hargiana, Giur Hasan Fuadi Hassan, Hamidah Hayani, Nuriah Hayuni Rahmah Hemi Fitriani Hening Pujasari Herita, Gusti Heryani, Heryani Hilman Syarif Hilman, Syarif Huriyanah, Huriyanah Ice Yulia Wardani Ida Ayu Made Ari Santi Tisnasari Ida Faridah Ida Faridah Iis Kholisoh Ikhsan Sodik Imalia Dewi Asih Imami Nur Rachmawati Imanuel, Yovan Indah Susilowati Indang Trihandini Indra, Ibaadi Ismiatin Ismiatin Isran, Isran Jamhari Jamhari Judith Dean Juliastuti, Dyah La Ode Abdul Rahman Laksono Trisnantoro Lastri Mei Winarni Laviana Nita Ludyanti Lela Larasati Lisa Fitzgerald Lismidiayati, Wiwin Luknis Sabri M Hasan Basri M. Syafwani Machli Riyadi Maelani susilowat Mangkuayu, Cluny Martina Maradona Maradona Mareti, Silvia Margaret I Fitch Maria Evarista Sugo Mataputun, Donny Richard Mega Ariska Meyke Rosdiana Misrawati Monna Maharani Hidayat Muaningsih Muaningsih Muaningsih, Muaningsih Muchtaruddin Mansyur Muhammad Syafwani Mulhaeriah, Mulhaeriah Murtiningsih Murtiningsih Mustikasari Mustikasari Nani Nurhaeni Nasution, Lina A. Nasution, Lina Anisa Ningsih, Indarti Dwi Ninik Yunitr Nolla Lisa Lolowang Nora Idiawati Nugraha, Rudi Osrika Sitompul Parmawati, Ika Patrisia, Irene Pius Almindu Leki Berek Prawesti, Aprilia D. Prawesti, Aprilia Dian Puji Astuti Puji Raharja Santosa Puspita Palupi Putri, Tissa Aulia R Ratnawati Ratnawati Rahmawati, Veronica Yeni Ratna Sitorus Ratna Sitorus Ratnawati, R Ratnawati Ratnawati, R Ratnawati Renie Kumalasari Ria Andjarwati Rini Rahmayanti Riri Maria Ristriyani, Rizka Riven Karundeng, Riven Rizka Ristriyani Rizka Ristriyani Rodiyatul Nadawiyah Eka Putri Rohmawati, Dwi Asih Rudi Rudi S. Setyowati Sabi’ah Khairi Santi Wahyuningsih Sari, Levi Anggriani Purnama Sari, Mulat Selamita, Selamita Septyani Windi Utami Setiasih, Diana Tri Budi Setiowati, Retno Setyowati . Setyowati . Setyowati Setyowati Setyowati Setyowati Setyowati Setyowati Setyowati Setyowati Setyowati Setyowati Setyowati, Sigalingging, Astika Irmawaty Sihombing, Ratna M. Siti Fatonah Siti Kurnasih Siti Maesaroh Siti Nurjannah So, Winnie KW. Solikin Solikin Sopiah, Siti Herlina Ali Sri Yona Styowati . Sudaryo, Mondastri Korib Suherman, Reni Suryani Hartati susanti, suryane sulistiana Susiladewi, Ida Ayu Md Vera Susiladewi, Ida Ayu Md. Vera Syamsul Firdaus Tanaka, Emiko Tengku Riza Zarzani N Tia Damayanti Tisnasari, Ida Ayu Made Ari Santi Titin Ungsianik Tri Budiati Triani Banna Tris Eryando Tuti Nuraini Tuti Nuraini Vella Yovinna Tobing Watanabe, Kumi Welly Vitriawan Widia Lestari Windy Natasya Al Baihaqi Wiranti, Isna Wiwik Handayani Wiwit Kurniawati Wulansari, Ika Yeni Rustina Yessi Andriani Yossie Susanti Eka Putri Yuhansyah Yuhansyah Yulia Irvani Dewi Yuliani Budiarti Yuliani Budiarti Yuliani Budiyarti Yuzia Melantika