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Siti Jubaidah, Siti
Akademi Farmasi Samarinda
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EKSPLORASI KEARIFAN LOKAL KHAS BORNEO: BIOSINTESIS NANOPARTIKEL PERAK EKSTRAK  ETANOL DAUN KOKANG (Lepishanthes amoena (Hass) Leenh) Aminah; Rahman, Nurul Aulia; Amalia, Sindi; Hardiani, Lia; Khairunnisa, Annida; Jubaidah, Siti; Puspita, Alfiana Dwi
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.528

Abstract

Biosynthesis of silver nanoparticles (AgNP) is a process of changing Ag+ ions to Ag0. The biosynthesis method in this research is green synthesis using natural ingredients to reduce silver, this synthesis is safer, environmentally friendly and economical. Based on this, this research aims to determine the optimal reaction conditions in the biosynthesis process using ethanol extract from cock leaves. The research method carried out pH optimization with variations of 8, 9, and 10 and then obtained the best pH, where the pH optimization will later be used in the AgNO3 optimization process with variations of 1mM, 2mM, and 4mM. After obtaining the best Ag optimization, the next stage was extract optimization using variations of 0.5%, 1% and 2%, the results of which will be seen based on the SPR peak of 400-500 nm which indicates the formation of AgNPs. The results of the research showed that AgNPs from cockang leaf ethanol extract were able to reduce at pH 8, AgNO3 2mM and 4mM, as well as 0.5% extract, and the contact time reaction showed a good formula for AgNP 1, AgNP2, AgNP3 which was indicated by the absorbance intensity at long waves that form AgNPs at the SPR peak of 400-500. Based on the results of SEM characterization, the morphology at a concentration of 2 mM has a surface that is not very smooth and the size is not very uniform, but at a concentration of 4 mM the surface is smooth and the particles are not uniform. With particle sizes in the range of 50-80 nm.
PENETAPAN KADAR FENOLIK TOTAL FRAKSI POLR DAN NONPOLAR DAUN RAMBAI LAUT (Sonneratia caseolaris L.) DENGAN METODE SPEKTROFOTOMETRI UV-Vis Jubaidah, Siti; Sundu, Reksi; Sabriningsih, Nur
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i2.23

Abstract

Rambai laut (Soneratia caseolaris L.) is a type of tree that grows in riverbank swamps or mangrove forests which contains one of the secondary metabolites in the form of phenolic compounds. The purpose of this study was to determine the total phenolic content of polar and nonpolar fractions of sea rambai leaves using UV-Vis spectrophotometry method. Research conducted is non-experimental. The stages of the study included the determination of plants, sampling, making samples, making extracts, determining the water content of extracts, fractionation using polar and nonpolar fractions, phytochemical screening test of ethanol extract and fractionation results and determination of total phenolic levels by UV-Vis spectrophotometry. The results showed that rambai laut leaf in polar fraction had a total phenolic content of 213.49 ± 1.2227 mg GAE / g, which means that in each gram the polar fraction is equivalent to 213.49 mg of gallic acid, whereas in the nonpolar fraction of rambai laut leaves is obtained 55.79 ± 1.0809 mg GAE / g which means that in each gram the nonpolar fraction is equivalent to 55.79 mg of gallic acid. Total phenolic content is greater in the polar fraction.
Co-Authors Abdul Syahid Adhila, Ghina Agustina, Alfina Anggerita Ahmad Fuad Ali Rakhman Hakim Aliurridha amalia, sindi Amaniarsih, Dwi Suci AMINAH Andri Ilham Annaza, Alwan Darwissy Anyeq, Andi Saputra Aqila, Nazwa asrul, nurmahyuni Aulia Safitri, Aulia Azizah, Nabila Nur Bahtiar, Ihwan Rahman Barnabas, Raden Ahmad Bayu Aji Nugroho, Bayu Aji Binta, Silmi Malina Chakam Failasuf Cholisotin, Tutik Dahri Dahlan, Dahri Derius, Rivaldo Dharma, Budi Eka Siswanto Syamsul Elfia, Novita Ferdiansyah Ferdiansyah Hadi Saputra Panggabean Handayani, Sella haniefa, rifda Hardiani, Lia Hayati, Firdha Henny Nurhasnawati Heri Wijaya, Heri Iftifa’iyah, Aisyiyah Dwi Ika Nurjannah, Ika Indriyani, Ria Ismiadi, Rahmad Johanda, Maulida Jumiati, Nisla Kavung, Clara Agatha Khairunnisa, Annida Khambali, Khambali Kornelia, Sindi Lestyorini, Vina Luluk Humairo Pimada Maharani, Andi Rika Mandasari, Lola Milasari, Novi Muh. Deni Kurniawan Muhammad Andrian, Muhammad Mulyani, Reny Nur Mustapa  Khamal  Rokan Mutmainah, Mia Nafi'ah, Khotimatun Nafi’ah, Khotimatun Naila, Alya Maida Novitasari Novitasari Nurindraswari, Ratu Ayu Nurleli, Nurleli Nuruddin, Nuruddin Pangaribuan, Rosa D. Pasaribu, Yogi Oriena Pratama, Muhammad Riyadi Pratama, Stevfanye Puspita, Alfiana Dwi Rahmadani Rahmadani Rahman, Nurul Aulia Rahmani, Nur Ahmadi Bi Ramadhan, Muhammad Marwan Reksi Sundu Risa Supriningrum Rosyada, Amirah Rukayyah, Rukayyah Rusdiati Helmidanora Sa'adah, Hayatus Sabriningsih, Nur Safira, Alya Safitri, Alfiyani Safitri, Sela Sagita, Ririn Salamah, Faqiha Nibros Saleky, Dandi Saputro, Joko Suryo Sarip, Mohamad Sihotang, Ina Yunita Siregar, Siti Aisyah Siti Azizah Siti Masyitoh Situmorang, Ferdinand C. Suhairi Suhairi Sukrin, Sukrin Sulistyowati Sulistyowati Syari, Aulia Rahma Tri Mulia Herawati Triswanto Sentat Veta, Anadafti Welliken K., Marius A. Wildana Wargadinata Yurisa, Penny Respaty Zahrach, Eca May Zain, Anwar