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All Journal HAYATI Journal of Biosciences Jurnal Natur Indonesia JBIO: jurnal biosains (the journal of biosciences) Jurnal Kedokteran Brawijaya Majalah Kedokteran Bandung Pharmaciana: Jurnal Kefarmasian JURNAL ILMU PERTANIAN Buletin Penelitian Tanaman Rempah dan Obat Global Medical and Health Communication Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Pharmascience The Indonesian Biomedical Journal Universa Medicina BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Jurnal Penelitian Pendidikan IPA (JPPIPA) Syntax Literate: Jurnal Ilmiah Indonesia Preventif Journal Jambura Journal of Health Sciences and Research Journal Health & Science : Gorontalo Journal Health and Science Community Seminar Nasional Lahan Suboptimal Jurnal Kesehatan Journal of Health Sciences Jurnal Pendidikan dan Konseling PREPOTIF : Jurnal Kesehatan Masyarakat Buletin Penelitian Tanaman Rempah dan Obat International Journal of Basic and Applied Science JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Buletin Kedokteran dan Kesehatan Prima JURNAL KIMIA SAINTEK DAN PENDIDIKAN International Journal of Health and Pharmaceutical (IJHP) Journal of Social Science JOURNAL OF CHEMICAL NATURAL RESOURCES (JCNaR) Jurnal Kedokteran STM (Sains dan Teknologi Medik) Ranah Research : Journal of Multidisciplinary Research and Development Jurnal Mahasiswa Ilmu Kesehatan Nutriture Journal
Edy Fachrial
Fakultas Kedokteran, Kedokteran Gigi Dan Ilmu Kesehatan, Universitas Prima Indonesia, Medan
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Inhibisi Enzim α-Glukosidase oleh Bacillus Megaterium ITU 9 Isolat Sumber Air Panas Sumatera Utara Piska, Finna; Ginting, Chrismis Novalinda; Harmileni, Harmileni; Fachrial, Edy
Jurnal Pharmascience Vol 11, No 1 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i1.17045

Abstract

Diabetes adalah penyakit multifaktor yang insidensinya meningkat dengan pesat di negara berkembang. Diabetes mellitus (DM) tipe 2 adalah jenis diabetes yang paling umum ditemui, dimana penyakit ini erat kaitannya dengan kemajuan industri dan teknologi sehingga mempengaruhi gaya hidup seseorang. Penanggulangan penyakit ini dapat dilakukan dengan menghambat aktivitas α-glukosidase. Beberapa mikroorganisme terutama dari sumber air panas dapat dimanfaatkan sebagai penghasil senyawa inhibitor α-glukosidase. Pada penelitian sebelumnya isolat Bacillus megaterium ITU 9 merupakan isolat yang diisolasi dari sumber air panas. Pada penelitian ini diuji kemampuan isolat Bacillus megaterium ITU 9 sebagai penghasil inhibitor α-glukosidase dengan metode sumur. Daya persen inhibisi supernatan B. megaterium ITU 9 terhadap kerja enzim α-glukosidase adalah sebesar 46,67%, sedangkan daya persen inhibisi acarbose yaitu 70%. Dalam hal ini B. megaterium ITU 9 termofilik memiliki daya inhibisi terhadap enzim α-glukosidase. Kata Kunci: Bakteri Termofilik, Inhibitor, Akarbose, Metode Sumur, Persen Inhibisi Diabetes is a multifactorial disease whose incidence is increasing rapidly in developing countries. Diabetes mellitus (DM) type 2 is the most common type of diabetes, where this disease is closely related to industrial and technological advances, thus affecting a person's lifestyle. This disease can be controlled by inhibiting α-glucosidase activity. Several microorganisms, especially from hot springs, can be used to produce α-glucosidase inhibitor compounds. In previous research, the Bacillus megaterium ITU 9 isolate was an isolate isolated from hot springs. In this study, the ability of the Bacillus megaterium ITU 9 isolate to produce α-glucosidase inhibitors was tested using the well method. The percent inhibition power of B. megaterium ITU 9 supernatant on the action of the α-glucosidase enzyme was 46.67%, while the percent inhibition power of acarbose was 70%. In this case, the thermophilic B. megaterium ITU 9 has inhibitory power against the α-glucosidase enzyme.
Efektivitas Ekstrak Etanol Daun Kenitu (Chrysophyllum cainito L.) sebagai Antidiabetes Tikus Putih Jantan (Rattus norvegicus L.) yang Diinduksi Aloksan : Natalia Desvalentina Lase; Girsang, Ermi; Fachrial, Edy
Jurnal Mahasiswa Ilmu Kesehatan Vol. 2 No. 3 (2024): Juli: Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v2i3.1411

Abstract

Meningkatnya jumlah kesakitan dan kematian akibat diabetes merupakan masalah kesehatan global. Secara klinis, penggunaan bahan kimia (obat hiperglikemik oral) secara berkelanjutan dapat memberikan efek yang buruk pada tubuh. Pernyataan ini membuat peneliti untuk melakukan penelitian mengenai obat antidiabetes yang terbuat dari bahan alami seperti tanaman kenitu (Chrysophyllum canito L.). Tujuannya adalah untuk melihat efektivitas pada ekstrak etanol daun kenitu (Chrysophyllum canito L.) sebagai antidiabetes serta kandungan kimia pada ekstrak etanol daun kenitu (Chrysophyllum canito L.) dan dosis efektif dari ekstrak etanol daun kenitu (Chrysophyllum canito L.) dalam mengurangi glukosa darah. Metode penelitian yang digunakan eksperimental laboratorium dengan 5 kelompok uji diantaranya K-, K+, dan kelompok dosis dengan konsentrasi 25, 50, dan 75 mg/kgBB. Hasil penelitian ditemukan ketidaksamaan yang bermakna antara kelompok K- dan kelompok K+ serta kelompok K- dan kelompok dosis, tetapi tidak ditemukan ketidaksamaan yang bermakna pada kelompok kontrol positif dan kelompok dosis. Kesimpulannya adalah  pemberian ekstrak etanol daun kenitu melalui dosis 25, 50, dan 75 mg/kgBB dapat mengurangi glukosa darah tinggi dikarenakan senyawa yang ada pada ekstrak etanol daun kenitu, yaitu tanin, flavonoid, saponin, alkaloid dan steroid. Dosis ekstrak yang efektif dalam mengurangi glukosa darah adalah 75 mg/kgBB.
AKTIVITAS Lactobacillus casei SEBAGAI PENURUN KADAR KOLESTEROL SECARA In Vitro Ritonga, Lestina; Saragih, Ria Natalia; Novriani, Erida; Fachrial, Edy
Journal Health & Science : Gorontalo Journal Health and Science Community Vol 8, No 3 (2024): JULI: JOURNAL HEALTH AND SCIENCE : GORONTALO JOURNAL HEALTH AND SCIENCE COMMUNIT
Publisher : Gorontalo State University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/gojhes.v8i3.26191

Abstract

Hiperkolesterolemia adalah di mana keadaan tingkat kolesterol dalam darah melebihi batas normal yang ditetapkan, yaitu melebihi 200 mg/dL. Bakteri asam laktat dapat digunakan sebagai terapi alternatif kemampuan untuk menurunkan kadar kolesterol. Kebaruan dari penelitian ini probiotik bakteri asam laktat memiliki manfaat terapeutik seperti kadar kolesterol dalam darah menurun dan mencegah terjadinya kanker usus. Tujuan dari penelitian ini adalah untuk mengetahui apakah Lactobacillus casei dapat menurunkan kolesterol secara in vitro. Metode penelitian aktivitas antimikroba dilakukan dengan metode disc paper, uji ketahanan terhadap pH asam, garam empedu dan pengurangan kolesterol dilakukan dengan metode spektrofotometer. Hasil penelitian uji aktivitas antimikroba isolat Lactobacillus casei menunjukkan aktivitas zona hambat terhadap bakteri E. coli sebesar 28,5 mm dan S. aureus sebesar 33,2 mm. Uji ketahanan terhadap pH asam sebesar 45,42%. Uji ketahanan terhadap garam empedu yaitu 55,39%, penurunan kadar kolesterol secara in vitro cukup baik yaitu 82,20%. Kontrol positif pengurangan kolesterol oleh simvastatin adalah 56,89%. Kesimpulan yang diperoleh dari penelitian ini adalah probiotik isolat Lactobacillus casei dapat menurunkan kadar kolesterol secara In Vitro.
Antiaging Cream Formula From Lemongrass Leaf Extract (Chymbopogon Citratus) Ramadhani, Shafira; Nyoman Ehrich Lister, I; Fachrial, Edy; Hakim Nasution, Ikhwanul
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 4 (2023): November 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i4.222

Abstract

This study aimed to determine the formula of anti-aging cream using lemongrass leaf extract. The treatment by giving respondents lemongrass leaf extract and using moisture, evenness, pore, spot, and wrinkle as parameters. Human skin provides protection on the surface of the body against the influence of the surrounding environment. Skin can experience aging, especially in areas that are often exposed to direct sunlight such as the face, neck, upper arms, and hands. Aging is a process experienced by humans in their 30s whose functions in the human body are decreasing, for example, thinning skin, wrinkles, rough skin, and dark spots on the face. Treatment to prevent aging of the skin by using an antioxidant product such as flavonoids because it has the function of preventing or neutralizing free radicals. In Indonesia, several species of plants can be found that function as food and cosmetic ingredients. The lemongrass leaf extract which contains antiaging are Alkaloids, Flavonoids, and Tannins. The data were analysed by using the Kolmogorov-Smirnov method to determine homogeneity and normality. Then, if the data is normal, it is continued to be analysed using the One-Way ANOVA method to determine the average difference between groups. There is a difference between treatments, and it is continued with the Post-hoc Tukey HSD test. The higher the concentration of extract used, the greater the anti-aging productivity formed. It is concluded, the best anti-aging effect is a concentration of 9% with increase in moisture, evenness, pore reduction, reducing spots and wrinkles.
Antiaging Cream Formula From Lemongrass Leaf Extract (Chymbopogon Citratus) Ramadhani, Shafira; Ehrich Lister, I Nyoman; Fachrial, Edy; Hakim Nasution, Ikhwanul
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 2 (2024): May 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.259

Abstract

This study aimed to determine the formula of anti-aging cream using lemongrass leaf extract. The treatment by giving respondents lemongrass leaf extract and using moisture, evenness, pore, spot, and wrinkle as parameters. Human skin provides protection on the surface of the body against the influence of the surrounding environment. Skin can experience aging, especially in areas that are often exposed to direct sunlight such as the face, neck, upper arms, and hands. Aging is a process experienced by humans in their 30s whose functions in the human body are decreasing, for example, thinning skin, wrinkles, rough skin, and dark spots on the face. Treatment to prevent aging of the skin by using an antioxidant product such as flavonoids because it has the function of preventing or neutralizing free radicals. In Indonesia, several species of plants can be found that function as food and cosmetic ingredients. The lemongrass leaf extract which contains antiaging are Alkaloids, Flavonoids, and Tannins. The data were analysed by using the Kolmogorov-Smirnov method to determine homogeneity and normality. Then, if the data is normal, it is continued to be analysed using the One-Way ANOVA method to determine the average difference between groups. There is a difference between treatments, and it is continued with the Post-hoc Tukey HSD test. The higher the concentration of extract used, the greater the anti-aging productivity formed. It is concluded, the best anti-aging effect is a concentration of 9% with increase in moisture, evenness, pore reduction, reducing spots and wrinkles.
The Effectiveness of ECE (Early Clinical Exposure) on the Integration of Basic Knowledge with Type 2 Diabetes Mellitus Clinical Knowledge and Interprofessional Collaboration in Medical Students of Prima Indonesia University Bella Sari Sijabat; Clarissa Lister; Edy Fachrial
Journal Of Social Science (JoSS) Vol 3 No 11 (2024): JOSS
Publisher : Al-Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/joss.v3i11.377

Abstract

Early Clinical Exposure (ECE) is a teaching-learning methodology that involves exposing medical students to patients or clinical scenarios early in the first year of medical education. In this study, the focus is on fifth-semester students, particularly on the integration of basic knowledge with clinical knowledge of Type 2 Diabetes Mellitus (DMT2), the role of multidisciplinary teams, and interprofessional collaboration. The purpose of this study is to determine the effectiveness of early clinical exposure in integrating basic knowledge with clinical knowledge of DMT2 and knowledge of interprofessional collaboration among medical students at Universitas Prima Indonesia. The method used in this research is a quantitative approach with an experimental design, specifically quasi-experimental research. In this design, 124 fifth-semester medical students from Universitas Prima Indonesia will be given a pretest before participating in Early Clinical Exposure (ECE) and a posttest after completing Early Clinical Exposure (ECE). The results of this study indicate a significant difference in the integration of basic knowledge with clinical knowledge of DMT2 and knowledge of interprofessional collaboration among medical students at Universitas Prima Indonesia, with a p-value of 0.000 (p < 0.05). Therefore, it can be concluded that Early Clinical Exposure (ECE) is effective in improving the integration of basic knowledge with clinical knowledge of DMT2 and knowledge of interprofessional collaboration among medical students at Universitas Prima Indonesia.
AKTIVITAS PROBIOTIK ISOLAT DNH 16 YANG DIISOLASI DARI DALI NI HORBO Vicky; Yasmin, Nabila; Sianturi, Naomi; Fachrial, Edy
JURNAL KIMIA SAINTEK DAN PENDIDIKAN Vol. 6 No. 2 (2022): Jurnal Kimia Saintek dan Pendidikan
Publisher : Program Studi Kimia - Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/kimia.v6i2.3496

Abstract

Dali Ni Horbo merupakan makanan tradisional khas batak yang difermentasi dari susu kerbau mengandung bakteri asam laktat bersifat probiotik yang dapat memberikan dampak positif terhadap kesehatan. Penelitian ini bertujuan untuk mengetahui karakterisasi probiotik isolat DNH 16 yang meliputi aktivitas antimikroba, toleransi terhadap asam dan garam empedu. Aktivitas antimikroba dilakukan terhadap Staphylococcus aureus menggunakan metode difusi cakram. Toleransi terhadap asam dan garam empedu dilakukan dengan menentukan pertumbuhan isolat pada media MRS Broth pH3 dan MRS Broth dengan 0,3 % garam empedu berturut – turut pada λ 600 nm. Hasil penelitian menunjukkan isolat DNH 16 berbentuk basil, katalase negatif, heterofermentatif. Aktifitas antimikroba dari isolat DNH 16 yaitu 4,6mm. Viabilitas pertumbuhan terhadap asam yaitu 91,6 %, viabilitas pertumbuhan terhadap garam empedu yaitu 66,5%. Hasil menunjukan bahwa isolat DNH 16 berpotensi sebagai bakteri probiotik.
Comparison of Interleukin-1b-511 C/T Polymorphism in Schizophrenia of Batak and Minangkabau Ethnicities in Pematang Siantar Wijaya, Raysha Awlia; Fachrial, Edy; Lister, I Nyoman Ehrich; Ariatama, Bayu
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.601-608

Abstract

This research is an overview of a comparative study on the Interleukin-1β-511 C/T polymorphism in individuals with schizophrenia of Batak and Minangkabau ethnicities in Pematang Siantar, Indonesia. The study aims to investigate genetic differences among these ethnic groups to better understand susceptibility to schizophrenia, which is influenced by multiple factors including genetics. The research uses a comparative categorical analytic approach with a cross-sectional method and involves DNA isolation and polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) examinations. Based on the results,  significant demographic differences between the Batak and Minangkabau ethnic groups, particularly in gender distribution, age, onset of illness, duration of illness, and PANSS scores. Notably, it finds a significant difference in the occurrence of the C allele and the T allele between the two ethnic groups, with the C allele being more prevalent in the Minangkabau group and the T allele more so in the Batak group. This suggests that the IL-1β -511 C/T polymorphism may play a differential role in the susceptibility to schizophrenia among these ethnicities, indicating a potential for ethnic-specific risk factors or protective elements.
Skrining Probiotik Asal Produk Komersil yang Berpotensi Sebagai Inhibitor a-Glukosidase Angelin Christin; Edy Fachrial
Ranah Research : Journal of Multidisciplinary Research and Development Vol. 7 No. 2 (2025): Ranah Research : Journal Of Multidisciplinary Research and Development
Publisher : Dinasti Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/rrj.v7i2.1402

Abstract

Various types of food products have good and bad effects on human health. One type of food that provides positive benefits is functional food. Functional foods are foods or beverages that are not only consumed to fulfill nutritional needs, but also provide good effects on the body's health and help reduce the risk of serious diseases. An example of functional food is probiotic drinks, which are known to support digestive health and strengthen the immune system. The content of probiotic drinks has a good impact on digestion and is able to inhibit α-glucosidase, so it is good to be consumed as a supplement for type 2 diabetes patients. The research focused on testing the potential of probiotics derived from commercial products on α-glucosidase enzyme activity. This type of research is laboratory experimental research with In Vitro method. The samples in this study are beverage samples with various types of brands containing probiotic milk that will be tested. The results showed that of the 8 probiotic isolates isolated from commercial products L-Bio, Yakult, Biokul and Max biotic have tolerance to acid and bile salt. Probiotic isolates in this study did not show antimicrobial activity. Screening of probiotics from commercial products with the most potential as α-glucosidase inhibitors was yakult.
Penyembuhan Luka Sayat menggunakan Gel Ekstrak Bawang Batak (Allium Chinense G. Don) : Studi Eksperimen pada Tikus Putih Waroka, Edward; Dharma, Surya; Fachrial, Edy
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 10, No 1 (2025)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/jumantik.v10i1.21604

Abstract

The primary function of skin is to protect the inside of the body from physical and mechanical stresses. Skin is perceptive to its surroundings. Thus, a variety of skin issues may develop, including wounds. The standard wound treatment is chemical therapy using antiseptics. Antiseptics contain antimicrobial qualities that can eradicate bacteria. However, antiseptics can also destroy fibroblast tissue, which creates new skin tissue, and leukocytes, which are responsible for eliminating harmful bacteria. Alternative medicines, such as traditional medicine, are thus required to aid in wound healing. The purpose of this research is to determine the effectiveness of Allium chinense G. Don extract on the healing of cut wounds in white rats. This research is experimental research using a post-test control group design. Data analysis used One way ANOVA. The research found that Allium chinense G. Don extract contained alkaloids, flavonoids, saponins, and triterpenoids/steroids, but no tannin compounds. The antibacterial properties of Allium chinense G. Don are effective against Pseudomonas aeruginosa and Staphylococcus aureus bacteria. Collagen density and fibroblast count increased in Wistar rat wound tissue after being treated with the extract. Allium chinense G. Don is effective in healing cut wounds in white rats (p <0,001).
Co-Authors Abednego S. Karosekali Adek Amansyah Adek Armansyah Afif P Jati Ainy, Al-Annisa Fadhila Aisar Novita Alhoi Hendry Henderson Aloysius Aloysius Aloysius, Aloysius Angelin Christin Anggita Kasih Fianti Situmorang Anggraini, Sari Anjurniza Ulfa Annisa Amalia Ariatama, Bayu Arma Citra Armansyah, Adek Bayu Pratomo Bella Sari Sijabat Buter Samin Buter Samin Calvin Christian Karo Karo Chiuman, Linda Chrismis Novalinda Ginting Christine Halawa Clarissa Lister Cory Oriensia Siahaan DAMERIA DAMERIA Dea Christa Amanda Deborah Angelin Purba Delyuzar, Delyuzar Dini Ariyska Edward Kosasih Edwin Waroka Ehrich Lister, I Nyoman Eka Susilawati Erika Yolanda Ginting Ermi Girsang Ermi Girsang Ester Putri Mentary Mendrofa Felix Felix Ferdinand, Sahna Fibrina, Dewi Fioni, Fioni Ginting, Chrismis Novalinda Girsang, Ermi Girsang, Ermi Hakim Nasution, Ikhwanul Hanna Christsela Purba Hanna Sari Widya Kusuma, Hanna Sari Widya Harmileni Henderson, Alhoi Hendry Henny Safrita Ginting I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Enrich Lister I. Nyoman Ehrich Lister Indra Setiawan Rambe Intan Hasibuan, Febria Nurul Intisari, Yayo Ira Manda Sari Berampu Ismawati Ismawati ismawati Juli elisabeth mayen Juli Elisabeth Mayen Meliala Juliana Lina Jusri, Ridza Karo Sekali, Abednego Suranta Khainir Akbar, Khainir Komala, William Laura J. Pinem Lela Diyana Br Tarigan Liana Liana Liena Liena Linda Chiuman Lisma Viany Lister Ehrich I Nyoman Lister, Clarissa Lister, I Nyoman Ehrich Lister, I Nyoman Ehrich Lister, I Nyoman Ehrich Lister, Nyoman Ehrich Lokot Donna Lubis M. Andriady Saidi Nst Marbun, Togi Rut Marlita Marpaung, Hans Hotma Masdalena Nasution Muhammad Aditya Kurnia Nabila, Pivi Naidu, Ramawathy Nasution, Muhammad Hasan Basri Natalia Desvalentina Lase Neswita, Elfia Niranti, Tasya Putri Novriani, Erida Nyoman Ehrich Lister, I Obet Edom Ginting Ongko, Nicolas Xavier Pinem, Laura Juita Piska, Finna pratomo, bayu Purba, Greace Hasianna Purba, Rosi Krisdayanti Qodariah, Rismawati Laila Rama Riana Sitinjak Ramadhani, Shafira Ricky Kinarta Sembiring Rika Silvany Rita Kusuma Ritonga, Lestina Rizal Rizal Rizal Rizal Rr. Anisa Siwianti Handayani Rudi Chandra Sahna Ferdinand Ginting Saipul Sihotang Saragih, Ria Natalia Sari Anggraini Saryono Saryono Saryono Sianturi, Naomi Silaban, Agnes Novica Putri Silalahi, Elsa Debora Sinaga, Ade Putra Fratama Siregar, Hafiz Hawari Siregar, Irma Dolsyeria Situmorang, Anggita Kasih Fianti Sofiyana, Maria Sonya Bonifacia Mahadi Sormin, Delores Elisabeth Sumartin, Sonia Apriani Sunarti Sunarti Surya Dharma Tandiah Asan Tarigan, Nuzulul Akbar Tengku Muhammad Sahiril Anhar Tengku Rachmi Hidayani Titania T Nugroho Titania Tjandrawati Nugroho Tri Widyawati Ulfa, Anjurniza Urip Harahap Vicky Vrianty, Dela Wahyu Widowati Wahyu Widowati WAHYU WIDOWATI Waroka, Edward Widodo, Wahyu Setia Widya Yanti Sihotang Wienaldi, Wienaldi Wijaya, Raysha Awlia Wilsen Wilsen Yasmin, Nabila Yonias Saleh Tria Zebua Yuliani Mardiati Lubis Yunita Dewani