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Morphological Analysis of Ciplukan Plant (Physalis angulata L.) Pollen for Macroscopic Identification Prasetyawan, Fendy; Saristiana, Yuneka; Akhmal Muslikh, Faisal; Hasriyani, Hasriyani; Dian Permatasari, Yunita
International Journal of Science and Environment (IJSE) Vol. 4 No. 1 (2024): February 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijse.v4i1.63

Abstract

This research addresses the prevalence of arthritis in Indonesia, focusing on traditional medicinal plants like Ciplukan due to the side effects of synthetic treatments. Arthritis, affecting 23.6-31.3% of the population, with Osteoarthritis (50-60% in the elderly) being the most common, necessitates alternative, less toxic remedies. Traditional medicine, relying on plant-derived remedies, is explored for its accessibility, affordability, and lower side effects. The study delves into Ciplukan, known for its anti-arthritis properties, conducting in vitro tests on its methanol extract. Results reveal anti-arthritis activity attributed to steroids, flavonoids, and alkaloids. The methodology involves macroscopic and microscopic examinations of Ciplukan plants, verifying authenticity and confirming the accuracy of plant samples. Organoleptic assessments highlight distinctive features, contributing to the plant's identification. Microscopic examination reveals the presence of stomata and palisade cells in the upper epidermis, aligning with literature data. The vascular system analysis emphasizes the efficiency of resource transport and adaptation to environmental changes. In conclusion, the study provides a comprehensive understanding of Ciplukan's characteristics, supporting its potential in arthritis treatment. The findings contribute to the utilization of traditional medicine in healthcare, emphasizing the importance of plant-based remedies with fewer side effects.
EVALUASI PENGGUNAAN OBAT PADA PASIEN HIPERTENSI RAWAT JALAN DI PUSKESMAS “X” KOTA SOLO Octavian Ashido Nababan; Isma Oktadiana; Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati
Jurnal Media Akademik (JMA) Vol. 2 No. 2 (2024): JURNAL MEDIA AKADEMIK Edisi Februari
Publisher : PT. Media Akademik Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62281/v2i2.185

Abstract

Hipertensi atau dikenal dengan “Silent Killer” yang merupakan pengukuran tekanan darah yang melebihi normal (140/90mmHg). Obat hipertensi dapat memberikan efek pada saat penggunaannya yang dapat menunjukkan sejauh mana obat yang telah diberikan mencapai terapi yang diharapkan secara praktik klinis. Penelitian ini bertujuan untuk mengetahui bagaimana penggunaan obat antihipertensi, efektivitas penggunaan dan perbandingan efektivitas obat antihipertensi tiap kelompok pada pasien. Penelitian ini merupakan penelitian secara deskriptif retrospektif, artinya didasarkan pada informasi yang diperoleh dari rekam medis pasien dengan melihat kejadian di masa lalu. Pada rekam medis dimasukkan data pasien hipertensi rawat jalan Puskesmas "X" Kota Solo pada bulan September 2023. Berdasarkan temuan penelitian, 40,30% pasien adalah laki-laki dan 59,70% pasien adalah perempuan. Terdapat 46 orang yang berusia lebih dari 60 tahun dan 21 pasien berusia antara 20 dan 60 tahun. Penggunaan antihipertensi sebagai obat tunggal digambarkan sebesar 35,82%, dan sebagai kombinasi, sebesar 64,18%. Studi tersebut mengklasifikasikan kemanjuran obat menjadi dua kategori: obat tunggal dan obat kombinasi. Dua kelompok telah dibandingkan mengenai kemanjuran antihipertensi individu. Hasil penelitian menunjukkan penggunaan obat pada beberapa golongan obat seperti CCB 41,67%. Golongan obat kombinasi CCB+ARB 46,51%. Karena obat antihipertensi mencapai target terapeutik tekanan darah sistolik sekitar 7-13 mmHg dan tekanan darah diastolic sekitar 4-8 mmHg. Perbandingan efektivitas antihipertensi Tunggal golongan ACEI Captopril (5.028/6.677). Golongan ARB Valsartan (16.666/5.715).
Virtual Socialization about the Use of Family Medicinal Plants (TOGA) as an Alternative for Treatment Ratna Mildawati; Bandhi Prasetya Nugroho; Fendy Prasetyawan; Ary Kristijono; Yuneka Saristiana; Isma Oktadiana; Arlan K Imran
Assoeltan: Indonesian Journal of Community Research and Engagement Vol. 1 No. 2 (2023): Indonesian Journal of Community Research and Engagement
Publisher : Edujavare Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70610/assoeltan.v1i2.270

Abstract

The use of plants as a treatment solution, whether as preventive, promotive or curative therapy, is becoming popular again with the public due to the trend of back to nature medicine. Family Medicinal Plants (TOGA) are plants that have medicinal properties and grow around community yards which are managed by families and planted to meet the family's medicinal needs. The development and utilization of family medicinal plant cultivation is very necessary to support public health. This activity is carried out in an effort to provide knowledge to improve health. The target of this health education activity is housewives. The activity method carried out in this community service is outreach using the lecture method and using power point slides which contain explanations of several types of superior family medicinal plants and by inviting the public to plant TOGA. The success of this community service is assessed from the target number of participants of 75%, achievement of goals of 80%, achievement of material targets of 80% and success of planting TOGA at home 80%. The conclusion of this community service is that TOGA education increases people's knowledge and understanding of TOGA
Asistensi Penyusunan Naskah Proposal Penelitian Dan Pengabdian Masyarakat Dengan Metode Lgd (Leaderless Group Discussion) Di Universtias Kadiri Prasetyawan, Fendy; Saristiana, Yuneka; Dhafin, Anis Akhwan; Mildawati, Ratna; Muslikh, Faisal Akhmal; Ariawan, Wahyu
Gotong Royong Vol. 1 No. 1 (2024)
Publisher : CV. Akira Java Bulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63935/gr.v1i1.16

Abstract

The assistance program for drafting research and community service proposals using the Leaderless Group Discussion (LGD) method at Universitas Kadiri aims to enhance the capacity of lecturers and students in producing high-quality and relevant proposals. The LGD method allows each participant to actively engage in discussions without a dominant leader, fostering involvement and constructive collaboration. The program includes preparation, workshop implementation, proposal evaluation, and follow-up stages. Results indicate significant improvements in problem formulation clarity, methodological accuracy, and proposal consistency. Additionally, active participant involvement and the development of collaborative skills were achieved, strengthening an inclusive discussion culture within the academic environment. Evaluations show that the LGD method effectively enhances academic and professional quality, despite challenges in ensuring deep understanding of topics and methodologies. With support from the Universitas Kadiri's Center for Educational Development and Quality Assurance (LP3M) team, this program successfully met its objectives and provides a strong foundation for similar future activities. The outcomes of this program are expected to contribute to improving the quality of innovative and impactful research and community service.
Evaluasi Efektifitas Penggunaan Uterotonika Misoprostol pada Induksi Persalinan Kehamilan Postterm Eka Nur Fatmawati; Ratna Mildawati; Yuneka Saristiana; Fendy Prasetyawan; Faisal Akhmal Muslikh
Jurnal Informatika dan Kesehatan Vol. 1 No. 1 (2024): IKN : Jurnal Informatika dan Kesehatan
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ikn.v1i1.3023

Abstract

Postterm pregnancy, namely pregnancy that reaches 42 weeks or exceeds 294 days which requires appropriate treatment and there are indications of labor induction. The principle of labor management in postterm pregnancy is the fulfillment of the requirements for induction of labor. The pharmacological induction method uses the uterotonic drug misoprostol. This research aims to evaluate and analyze the cost effectiveness of using the uterotonic misoprostol in labor induction of postterm pregnancies. This research method is descriptive observation using a cross-sectional research design from a hospital perspective. Retrospective data collection method. Evaluation of the effectiveness of using the uterotonic misoprostol with percentages. The results of this study show the pattern of use of misoprostol uterotonics (73.5%), the use of uterotonics is in accordance with hospital guidelines (96%), the effectiveness of using uterotonics is successful in preventing bleeding (57.4%). And analysis of the cost effectiveness of using misoprostol and oxytocin in labor induction at RSUD dr. Sayidiman Magetan can conclude that misoprostol uterotonic is more effective with a percentage value of 60%. Abstrak Kehamilan postterm, yaitu kehamilan yang mencapai 42 minggu atau melewati 294 hari yang memerlukan penanganan tepat dan muncul indikasi dilaksanakan induksi persalinan. Prinsip penatalaksanaan persalinan pada kehamilan postterm adalah terpenuhinya syarat-syarat melakukan induksi persalinan. Metode induksi farmakologis menggunakan obat uterotonika misoprostol. Pelitian ini bertujuan untuk mengevaluasi dan analisis efektifitas biaya penggunaan uterotonika misoprostol pada induksi persalinan kehamilan postterm. Metode penelitian ini observasi deskriptif dengan menggunakan rancangan penelitian cross sectional menurut perspektif rumah sakit. Metode pengambilan data secara retrospektif. Evaluasi efektifitas penggunaan uterotonika misoprostol dengan persentase. Hasil penelitian ini menunjukkan pola penggunaan uterotonika misoprostol (73,5%), penggunaan uterotonika sudah sesuai dengan guideline rumah sakit (96%), efektifitas penggunaan uterotonika berhasil mencegah perdarahan (57,4%). Dan analisis efektifitas biaya penggunaan misoprostol dan oksitosin pada induksi persalinan di RSUD dr. Sayidiman Magetan dapat disimpulkan uterotonika misoprostol lebih effective dengan nilai persentase 60 %.
Studi Analisa Kronofarmakologi Penggunaan Obat Ibuprofen pada Pasien Covid-19 di Rawap Inap RSUD Dr. Soedomo Trenggalek Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati; Chandra Arifin; Abd Rofiq; Emma Jayanti Besan; Muhammad Nurul Fadel; Charliandri Saputra Wahab; Muhammad Alviyan Shutiawan
Jurnal Informatika dan Kesehatan Vol. 1 No. 1 (2024): IKN : Jurnal Informatika dan Kesehatan
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ikn.v1i1.3024

Abstract

The global COVID-19 pandemic has presented unprecedented challenges to global health. The Dr. Soedomo Regional General Hospital in Trenggalek has been at the forefront of managing COVID-19 patients, with a primary focus on the use of ibuprofen to alleviate symptoms such as fever and pain. Despite the widespread use of ibuprofen, knowledge regarding its interaction with the circadian rhythm, especially in COVID-19 patients, remains limited. This study employed an analytical observational approach with a Cross-Sectional design to analyze the use of ibuprofen in COVID-19 patients at Dr. Soedomo Regional General Hospital in Trenggalek. The study included 100 patients, emphasizing body temperature at three different times. Data analysis revealed a significant decrease in body temperature after therapy, particularly at 4:00 PM. These findings lay the foundation for the development of more targeted and personalized treatment strategies by understanding the body's response patterns to therapy at different times.   Abstrak Pandemi global COVID-19 telah menciptakan tantangan kesehatan global yang belum pernah terjadi sebelumnya. Rumah Sakit Umum Daerah Dr. Soedomo di Trenggalek telah menjadi pusat perhatian dalam menangani pasien COVID-19. Fokus utama adalah penggunaan ibuprofen untuk mengelola gejala, seperti demam dan nyeri. Meskipun ibuprofen umum digunakan, pengetahuan tentang interaksi dengan siklus sirkadian tubuh, terutama pada pasien COVID-19, masih terbatas. Penelitian ini menggunakan pendekatan observasional analitik dengan desain Cross Sectional untuk menganalisis penggunaan ibuprofen pada pasien COVID-19 di RSUD Dr. Soedomo Trenggalek. Hasil penelitian melibatkan 100 pasien, dengan fokus pada suhu tubuh pada tiga waktu berbeda. Analisis data menunjukkan penurunan suhu tubuh yang signifikan setelah terapi, terutama pada pukul 16.00 WIB. Hasil ini memberikan dasar untuk pengembangan strategi pengobatan yang lebih terarah dan personalisasi, dengan memahami pola respons tubuh terhadap terapi pada waktu yang berbeda.
Utilization of Antiviral Medications in COVID-19 Patients with Chronic Kidney Disease in Hospital Yuneka Saristiana; Fendy Prasetyawan; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Ratna Mildawati; Elsa Mahardika Putri; Susilo Margining Raharjo
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i1.7284

Abstract

The COVID-19 pandemic has presented a substantial global health challenge, affecting diverse patient populations, particularly those with chronic kidney disease. Hospitals are presently dependent on two antiviral medications, favipiravir and remdesivir, to mitigate the impact of this disease on patients with chronic kidney disease. This study aims to evaluate the utilization of favipiravir and remdesivir in COVID-19 patients with chronic kidney disease in a hospital setting. This research will employ a retrospective approach to gather data from the medical records of COVID-19 patients with chronic kidney disease who received treatment with favipiravir or remdesivir in the hospital. Considering the prevalence of favipiravir usage at 64% and remdesivir at 36%, this research aims to provide a comprehensive understanding of the effectiveness and associated risks of toxicity linked to these two medications in COVID-19 patients with chronic kidney disease
Farmakoantartika Literature Study: Bioactivity of Pagodroma nivea on Fossil Deposits from Mujito Yuneka Saristiana; Fendy Prasetyawan; Ratna Mildawati; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Susilo Margining Raharjo; Candra Arifin; Abd Rofiq
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7593

Abstract

This report investigates the biodiversity of marine animals, focusing on extinct sponge species near Lesbos Island based on Aristotle's descriptions. Mujito, introduced in the literature review, is from the GeoMaud expedition in Antarctica. Various instrumental analysis methods, such as ESI mass spectrometry and NMR, contribute to a comprehensive understanding of the compounds, particularly in the context of Alzheimer's research. The pharmacantarctic literature study concludes that Antarctic Mumijo, particularly from Mujito fossil deposits, holds significant biomedical potential. It exhibits organic components like wax esters with notable biomedical activities, particularly in treating bone diseases. Additionally, Mumijo's composition resembles non-fossil samples, with wax esters dominating and unique components like α-glyceryl fatty alcohol ethers indicating neuroprotective potential. The research suggests promising applications in Oriental medicine, addressing wounds, skin diseases, tuberculosis, respiratory diseases, and neurological conditions like Parkinson's and Alzheimer's. Overall, Antarctic Mumijo showcases diverse biomedical prospects, emphasizing its organic components' therapeutic value
Forensic Pharmacy Case Study: Identification of Hazardous Mercury Content as a Whitening Agent in Beauty Cream Products Nanda Ardianto; Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati; Anis Akhwan Dhafin; Candra Arifin; Abd Rofiq
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7594

Abstract

Forensic pharmacy is crucial in identifying hazardous substances like mercury in beauty products. Counterfeit items with mercury pose health risks, emphasizing the need for accurate identification methods. The research, employing content analysis, focuses on illegal cosmetics containing mercury, aiming to understand distribution patterns and assess associated health risks. This systematic approach provides valuable insights into public health issues, contributing to safer regulatory practices. The utilization of these products may pose serious health risks to consumers. The implicated products include Temulawak New Day & Night, CAC Glow, Natural 99, HN (Day & Night), SP Special UV Whitening, Dr Original Pemutih, Super DR Quality Gold SPF 30, Diamond Cream, Herbal Plus New Day & Night, Ling Zhi Day & Night, Sj Sin Jung, Tabita, and Krim Labella. In Indonesia, the use of mercury in cosmetic products is prohibited by legislation, such as Law Number 32 of 2009 on Environmental Protection and Government Regulation of the Republic of Indonesia Number 81 of 2016 on the Security of Industrial Chemicals. Additionally, BPOM, responsible for overseeing drugs, food, and cosmetics, has issued relevant regulations
Pharmacy Philosophy in the Law of Power: The Morality of Pharmaceutical Ethics towards Rhetoric of Logic Adiyansyah Lukman Hakim; Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Ratna Mildawati; Candra Arifin; Abd Rofiq
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7595

Abstract

Pharmacy's evolution relies on technical and philosophical aspects. Research delves into the intricate link between pharmaceutical philosophy and legal power, emphasizing moral values in daily practice. The study aims to enhance policies, regulatory frameworks, and awareness, optimizing pharmacy's pivotal role in healthcare services. The results of this study depict an investigation and comprehension of the close interconnection between the philosophy of pharmacy, the law of power, the morality of pharmaceutical ethics, and rhetorical logic. A profound integration of these four aspects can provide a solid foundation for the development of ethical policies, maintaining the integrity of the pharmacy profession, and maximizing benefits for society. A deeper understanding of the complexity of these relationships can help shape a more sustainable and ethical future in the field of pharmacy. The findings of this research depict the complexity of these relationships, highlighting that deep integration can provide a solid foundation for ethical policies and the sustainable future of pharmacy
Co-Authors Abd Rofiq Abd Rofiq Abd Rofiq Abd Rofiq Achmad Wahdi Adiyansyah Lukman Hakim Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Anita Dwi Setyarini Arifani Siswidiasari Arikha Ayu Susilowati Arsiaty Sumule Ary Kristijono Ary Kristijono Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Bandhi Prasetya Nugroho Besan, Emma Jayanti Candra Arifin Chandra Arifin Chandra Arifin Chandra Arifin Chandra Arifin Charliandri Saputra Wahab Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Edda, Ilda Rambu Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo, Elfred Rinaldo Elsa Mahardika Putri Elsa Mahardika Putri Ema Jayanti Besan Ema Tri Wulan Emma Jayanti Besan Faisal Akhmal Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hasriyani Hasriyani Hasriyani, Hasriyani Herman Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Ilhawa Zahra Imran, Arlan K Indrayanti, Dian Isma Oktadiana Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kholis, Muhammad Akbar Nur Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lusiana Aprillia M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Nanda Ardianto Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Octavian Ashido Nababan Okky Intan Mawarni Oktadiana, Isma Prayoga Fery Yuniarto Probosiwi , Neni Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda savitri, Lisa Shinta Mayasari Shinta Mayasari Sugeng, Santoso Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Wahyu Ariawan Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Yunita Dian Permatasari