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All Journal PHARMACON Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Well Being Jumat Ekonomi: Jurnal Pengabdian Masyarakat Journal of Social Responsibility Projects by Higher Education Forum Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) IJF (Indonesia Jurnal Farmasi) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Hasil Inovasi Masyarakat (JHIM) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara Jurnal Cendekia Ilmiah Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Abdimas Paspama Jurnal Bioteknologi & Biosains Indonesia Journal of Advanced Pharmaceutical Research Sciences and Sustainability Jurnal Pengabdian Inovatif Multidisipliner Fundamental and Applied Research in Medicine and Allied Sciences Indonesia Profixa: International Journal of Economic and Business Research
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ANALISIS KRONOFARMAKOLOGI PENGGUNAAN PARACETAMOL PADA PASIEN COVID-19 DI RSUD DR. SOEDOMO TRENGGALEK Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Mildawati, Ratna; Oktadiana, Isma; Arifin, Chandra; Rofiq, Abd; Febriana, Laela; Besan, Emma jayanti; Fadel, Muhammad Nurul
Journal of Social Science and Multidisciplinary Analysis Vol. 1 No. 1 (2024): Journal of Social Science and Multidisciplinary Analysis (Jossama), February 20
Publisher : Noble Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The global COVID-19 pandemic has presented complex challenges to global health. Dr. Soedomo Regional General Hospital in Trenggalek has actively engaged in managing COVID-19 patients. This study aims to analyze the chronopharmacology of paracetamol usage in COVID-19 patients at the hospital, focusing on the body's biological response to the drug at various time points within the 24-hour cycle. In the treatment of COVID-19, the use of paracetamol has become a primary strategy for addressing symptoms such as fever. However, it is crucial to understand how the timing of paracetamol administration can influence the body's response to the treatment. A chronopharmacological study involving 100 patients analyzed body temperature before and after therapy at three different times: 08:00 AM, 04:00 PM, and 10:00 PM. The results revealed a significant decrease in body temperature after therapy, particularly at 04:00 PM. These findings support the concept of "the right time, the right dose" in clinical practice. Analysis of the body's circadian rhythm emphasizes the need to consider the timing of drug administration to achieve optimal outcomes. Despite the limited sample size, this research provides a foundation for the development of more precise practical guidelines for administering paracetamol to COVID-19 patients.
The Comparison of The Use of Antiviral Drugs Favipiravir and Remdesivir on The Outcome of Covid-19 Patients at RSM Ahmad Dahlan Fendy Prasetyawan; Lisa Savitri; Yuneka Saristiana; Shinta Mayasari; Novyananda Salmasfattah
J-CEKI : Jurnal Cendekia Ilmiah Vol. 4 No. 2: Februari 2025
Publisher : CV. ULIL ALBAB CORP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/jceki.v4i2.7888

Abstract

This study aims to compare the usage patterns, effectiveness, and therapy outcomes of two antiviral drugs, Favipiravir and Remdesivir, in the treatment of COVID-19 at Muhammadiyah Ahmad Dahlan Hospital, Kediri City. A total of 71 medical records of patients treated with Favipiravir and 50 treated with Remdesivir were analyzed, focusing on patient demographics, drug usage, and therapy outcomes. The patient characteristics reveal that Favipiravir was more commonly used in older patients (aged >65 years), while Remdesivir was more frequent in younger patients (aged 0-5 years). In terms of drug usage, Favipiravir was prescribed to 58.7% of patients, compared to 41.3% for Remdesivir. Both antivirals demonstrated high recovery rates, with Favipiravir achieving a 100% recovery rate and Remdesivir 98%. Evaluation of drug effectiveness showed that Favipiravir was superior in reducing CRP levels (34.78) compared to Remdesivir (7.74), while Remdesivir had a shorter average length of stay (5.68 days) than Favipiravir (8.67 days). These findings suggest that while Favipiravir is more effective in reducing inflammation, Remdesivir is more efficient in accelerating patient recovery. Both drugs play significant roles in COVID-19 management, with their use tailored to patient needs.
Chronopharmacological Study Of Angiotensin-Converting Enzyme Inhibitor Ramipril In Hypertensive Patients In A Hospital: Analysis Of Efficacy And Tolerability Based On Administration Time Variations Fendy Prasetyawan; Faisal Akhmal Muslikh; Yuneka Saristiana; Ratna Mildawati; Chandra Arifin; Abd Rofiq; Dewi Retno Puspitosari
Jurnal Ilmiah Multidisiplin Indonesia (JIM-ID) Vol. 3 No. 02 (2024): Jurnal Ilmiah Multidisiplin Indonesia (JIM-ID), July 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/esaprom.v3i02.4752

Abstract

This research investigates the chronopharmacological effects of Ramipril administration on hypertensive patients, focusing on the timing of drug intake. Studies conducted by Firli Choerun Nisa and Siti Rohmiati in 2022 provide the basis for this analysis. Using observational-analytic methods with cross-sectional designs, data were collected prospectively from 23 patients in each study. Firli Choerun Nisa's study at RSUD Singaparna Medika Citrautama, Tasikmalaya Regency, involved 14 patients in the light zeitgeber group and 9 in the dark zeitgeber group. Results indicated significant reductions in both systolic and diastolic blood pressures, with the dark zeitgeber group experiencing more substantial decreases. The SPSS analysis showed a p-value of 0.062, indicating no statistically significant difference between the groups. Siti Rohmiati's study at RSUD Dr. Soekardjo Tasikmalaya found similar results. The light zeitgeber group showed a systolic decrease of 9.9 mmHg and a diastolic decrease of 5 mmHg, while the dark zeitgeber group had decreases of 16.66 mmHg and 10.56 mmHg, respectively. The SPSS analysis also yielded a p-value of 0.062, supporting the conclusion of no significant difference in Ramipril's efficacy based on administration timing. The comprehensive analyses revealed that Ramipril effectively reduces blood pressure regardless of the administration time. Significant reductions in both the daytime and nighttime groups were noted, with trends suggesting a more pronounced effect during nighttime administration. These findings emphasize the importance of flexibility in medication timing, enhancing patient adherence without compromising therapeutic outcomes. In conclusion, the timing of Ramipril administration, whether in the morning or evening, does not significantly impact its effectiveness in managing hypertension. This flexibility offers practical benefits for clinical practice, supporting better patient adherence and optimized hypertension management. These studies contribute to the broader understanding of chronopharmacology, providing insights for improved treatment strategies in hypertensive care.
Education on the Use of Over-the-Counter Drugs as Preventive Health for Students at SMP Muhammadiyah 2 Kediri Fendy Prasetyawan; Lisa Savitri; Yuneka Saristiana; Novyananda Salmasfattah
Joong-Ki : Jurnal Pengabdian Masyarakat Vol. 4 No. 2: Februari 2025
Publisher : CV. Ulil Albab Corp

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/joongki.v4i2.7743

Abstract

This community service activity was conducted on September 20, 2024, to raise awareness among students about the safe and responsible use of over-the-counter (OTC) medications. The primary objective was to educate students on the types of OTC medications available, their proper use, potential side effects, and the importance of reading medication labels. The event involved 20 students, comprising 4 from Grade 8, 7 from Grade 9, and 9 from Grade 7, who actively participated in interactive discussions and Q&A sessions. The educational session was delivered using a combination of presentations, visual aids, and real-life examples to enhance comprehension. A post-activity evaluation through a quiz was conducted to assess the participants' understanding of the material. The results showed an average quiz score of 82.3%, with an accuracy rate of 87.6%, indicating a significant improvement in the students' knowledge of OTC medication use. The activity also included discussions on the importance of adopting healthy lifestyle habits as a preventive health measure, which resonated well with the students, reflecting their growing interest in maintaining overall health.
Edukasi Pembuatan Pakan Silase Ruminansia dengan Kultur Campuran Lactobacillus sp., Rhodopseudomonas sp., Actinomycetes sp., Streptomyces sp., dan Yeast Savitri, Lisa; Prasetyawan, Fendy; Saristiana, Yuneka; Juwita, Syntia Tanu; Yanti, Novirma; Edda, Ilda Rambu
Abdimas Galuh Vol 7, No 1 (2025): Maret 2025
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v7i1.18152

Abstract

Pada musim kemarau, ketersediaan tumbuhan alami seperti rumput dan kacang-kacangan menurun, menyebabkan kesulitan bagi peternak dalam memenuhi kebutuhan pakan ternak ruminansia. Hal ini dapat berdampak negatif pada kesehatan dan produktivitas hewan ternak. Pakan ternak ruminansia terdiri dari berbagai jenis makanan, terutama tumbuhan, seperti rumput, kacang-kacangan, dan tanaman lain yang kaya serat dan nutrisi. Tumbuhan ini merupakan sumber utama energi bagi hewan ternak ruminansia seperti sapi, domba, dan kambing. Namun, selama musim kemarau, kekurangan tumbuhan menjadi tantangan utama. Salah satu solusi yang diusulkan adalah pembuatan silase. Silase adalah jenis pakan yang dihasilkan dari proses ensilase, di mana tumbuhan seperti rumput diawetkan dengan mengurangi kadar oksigen dan meningkatkan kadar asam laktat. Proses ini membantu mengawetkan nutrisi dalam tumbuhan dan menyediakan pakan tambahan untuk ternak saat musim kemarau. Program pengabdian masyarakat ini bertujuan untuk memberikan edukasi kepada peternak mengenai teknik pembuatan silase ruminansia menggunakan kultur campuran bakteri tertentu. Diharapkan program ini dapat meningkatkan pengetahuan dan keterampilan peternak dalam memproduksi pakan silase untuk memenuhi kebutuhan ternak ruminansia selama musim kemarau. Universitas Kadiri melalui program Pengabdian Masyarakat ini dapat ikut berkontribusi dalam upaya untuk mendukung program pemerintah yaitu “Making Indonesia 4.0” dalam peningkatan kualitas sumber daya manusia (SDM) dan pembangunan ekosistem inovasi. Melalui publikasi ilmiah, panduan, dan peningkatan pemahaman masyarakat, program ini diharapkan dapat memberikan dampak positif bagi peternak dan ekonomi lokal.
Increasing Awareness Among Teenagers About Preventing Non-Communicable Diseases Through The Use Of Multimedia At Karang Taruna Wates Bandhi Prasetya Nugroho; milda, ratna; Fendy Prasetyawan; Baarik Lana Fadli; Yuneka Saristiana; Isma Oktadiana; Arsiaty Sumule
Amaluna: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2024)
Publisher : Institut Agama Islam Negeri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/amaluna.v3i1.3408

Abstract

Non-Communicable Diseases (NCDs) are currently a serious health problem in the world, because these diseases are one of the most common causes of death. Community empowerment in preventing PTM through community components, one of which is youth organizations or youth organizations which have an important role in taking part, is expected to be able to prevent PTM through various more interesting media. The aim of this community service is to provide PTM education through the use of multimedia. The method used is to convey information accompanied by posters, pictures and discussions. After providing education, it is hoped that youth organizations will be able to be more critical about PTM and be able to provide further education to the wider community, especially in the Wates area, by utilizing multimedia. Keywords: Non-communicable diseases, Karang Taruna, Multimedia
Education about worms through animated videos for early childhood Ana Amalia; milda, ratna; Fendy Prasetyawan; Yuneka Saristiana; Isma Oktadiana; Arsiaty Sumule
Amaluna: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2024)
Publisher : Institut Agama Islam Negeri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/amaluna.v3i1.3431

Abstract

This worm disease can infect all ages, but those who are most susceptible to infection are children under five and elementary school age (SD) aged 5 to 14 years. To be able to break the chain of worm infections and reduce the number of worm infections in schools, this can be done by providing information or education. Providing education about worms can increase students' knowledge regarding preventing worms. The aim of this activity is to increase the knowledge of students and girls in preventing worms. The method of this service is to provide education using animated video media about worm disease and hand washing demonstrations. After counseling and demonstrations, the results of the education that has been provided will be evaluated using a questionnaire to evaluate students' knowledge of worms and their prevention after 1 week of providing counseling via educational video media. The results of the activity showed an increase in knowledge and psychomotor skills after being given education regarding worms and washing hands. It is hoped that increasing understanding of the dangers of worms can foster awareness and independence in preventing worms in families and communities. Keywords: Worms, education, animated video
Protective Role of Paederia foetida L. Against Hepatic Inflammatory Response in a Mice Model of Escherichia coli-Induced Sepsis Savitri, Lisa; Freitas, Maria Do Carmo Da Costa; Prasetyawan, Fendy; Saristiana, Yuneka; Mebung, Konradus Klala; Amanda, Cornelia
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.363-368

Abstract

Sepsis is a severe medical condition characterized by a systemic immune response to infection, often leading to multi-organ failure and death if not treated effectively. This study aimed to investigate the antiseptic properties of Paederia foetida leaf extract in male mice induced with sepsis using Escherichia coli. A total of 24 mice were divided into six groups: a normal group (no treatment), a negative control group (distilled water), a positive control group (ciprofloxacin), and three treatment groups receiving P. foetida leaf extract at doses of 100, 300, and 500 mg/kg BW. After 15 days of oral administration, liver tissue samples were analyzed for IL-6 expression, a pro-inflammatory cytokine associated with sepsis. The results revealed a significant reduction in IL-6 expression in the treatment groups, particularly at the 500 mg/kg BW dose. This dose showed the most effective anti-inflammatory response, with IL-6 expression levels comparable to those of the positive control group treated with ciprofloxacin. However, the 100 mg/kg BW dose demonstrated minimal effects, similar to the negative control. These findings suggest that P. foetida leaf extract, especially at higher doses, has potential as an anti-inflammatory agent in sepsis management. The bioactive compounds in the extract, including flavonoids, alkaloids, and terpenoids, likely contribute to its efficacy. This study provides preliminary evidence supporting the use of P. foetida as a potential herbal alternative for managing sepsis, but further clinical research is necessary to confirm its therapeutic potential.
Education on the Use of Vitamin A (Retinol) for the Prevention of Myopia in Adolescents in Gembleb Trenggalek: Edukasi Penggunaan Obat Vitamin A (Retinol) Untuk Pencegahan Penyakit Miopi Pada Remaja di Dusun Gembleb Trenggalek Prasetyawan, Fendy; Saristiana, Yuneka; Salmasfattah, Novyananda; Savitri, Lisa; Herman; Kadir, Mujtahid Bin Abd
KOMUNITA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 4 No 2 (2025): Mei
Publisher : PELITA NUSA TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60004/komunita.v4i2.177

Abstract

This community service program aimed to increase adolescents' awareness and knowledge regarding the role of Vitamin A (Retinol) in preventing myopia, particularly in rural areas such as Gembleb Village, Trenggalek. The activity was conducted on Saturday, May 3, 2025, in collaboration with the Government of Gembleb Village and supported by the Institute for Research, Community Service, and Publication (LP3M) of Universitas Kadiri. A total of 15 adolescents participated in the educational intervention, which included a pre-test, a lecture session, and a post-test evaluation. The results showed a significant improvement in participants’ knowledge about myopia and the importance of Vitamin A for eye health. Pre-test scores averaged lower compared to post-test results, with an average increase of 20–25 points. This finding suggests that structured education can effectively enhance health literacy among youth, particularly regarding nutritional prevention of visual disorders. These outcomes underscore the importance of continued community-based health education programs, especially in underserved areas, as a strategic effort to reduce the prevalence of preventable eye diseases
Education on the Benefits of Red Ginger (Zingiber officinale) to Overcome Menstrual Pain in Adolescent Girls in Gembleb Trenggalek: Edukasi Manfaat Jahe Merah (Zingiber officinale) Untuk Mengatasi Nyeri Haid Pada Remaja Putri di Dusun Gembleb Trenggalek Saristiana, Yuneka; Prasetyawan, Fendy; Salmasfattah, Novyananda; Savitri, Lisa; Megasari, Elly; Indrayanti, Dian
KOMUNITA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 4 No 2 (2025): Mei
Publisher : PELITA NUSA TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60004/komunita.v4i2.178

Abstract

This community service program aimed to educate adolescent girls in Dusun Gembleb, Trenggalek, on the benefits of red ginger (Zingiber officinale) as a natural remedy for alleviating menstrual pain. Menstrual pain, or dysmenorrhea, is a common health issue affecting a significant number of adolescent girls, often leading to disruption in daily activities. While conventional pain relief medications are commonly used, their long-term side effects can be detrimental. Red ginger, known for its anti-inflammatory and analgesic properties, offers a safer alternative. The program, held on May 3, 2025, at the Gembleb Village Office, included educational sessions on the medicinal properties of red ginger, practical demonstrations on how to prepare red ginger tea, and discussions on its health benefits. The results showed a significant improvement in participants' understanding of red ginger's therapeutic effects, as evidenced by pre-test and post-test comparisons. This initiative successfully raised awareness about alternative treatments and empowered the community to utilize locally available resources for health improvement.
Co-Authors Abd Rofiq Abd Rofiq Achmad Wahdi Achmad Wahdi Adiyansyah Lukman Hakim Akhmal, Faisal Ali Anhar Syi’bul Huda Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anggun Wida Prawira Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arsiaty Sumule Ary Kristijono Asrizal Azis Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Chandra Arifin Charliandri Saputra Wahab Cornelia Amanda Dara Sukma Ratmelya Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Edda, Ilda Rambu Eka Hayati Rhomah Eka Hayati Rhomah Eka Nur Fatmawati Eka Nur Fatmawati Eko Retnowati Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo, Elfred Rinaldo Elly Rachmawati Ratnaningrum Elsa Mahardika Putri Elsa Mahardika Putri Ema Jayanti Besan Ema Tri Wulan Ema Tri Wulan Emma Jayanti Besan Emma Jayanti Besan Emma Jayanti Besan Faisal Akhmal Muslihk Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hakim, Adiyansyah Lukman Hartini, Putri Tri Hasriyani Hasriyani Hasriyani Hasriyani Hasriyani, Hasriyani Herman Herman Herman Husnunnisa Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Ilhawa Zahra Imam Agus Faizal Imran, Arlan K Indrayanti, Dian Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Karingga, Devangga Darma Kharisul Ihsan Kholis, Muhammad Akbar Nur Khumaini, Eko Hidayaturrohman Konradus Klala Mebung Kristjono, Ary Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lisa Savitri Lisa Savitri Lusiana Aprillia M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri, Meri Meri, Meri milda, ratna Mildawati, Ratna Mohammad Firdaus Alshol Muhammad Al Farizzie Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Mujtahid Bin Abd. Kadir Mujtahid Bin And Kadir Nanda Ardianto Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Nur Masyithah Zamruddin Octavian Ashido Nababan Okky Intan Mawarni Okky Intan Mawarni Oktadiana, Isma Prasetyo Nugroho, Bandhi prayoga fery yuniarto Probosiwi , Neni Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Wati Ratna Mildwati Restyana, Anggi Rhomah, Eka Hayati Rika Murhayanti Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda Shinta Mayasari Shinta Mayasari Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Widhi Astutik Widhi Astutik Widhi Astutik Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Yunita Dian Permatasari Ziza Putri Aisyia Fauzi