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All Journal PHARMACON Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Well Being Jumat Ekonomi: Jurnal Pengabdian Masyarakat Journal of Social Responsibility Projects by Higher Education Forum PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Hasil Inovasi Masyarakat (JHIM) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara Jurnal Cendekia Ilmiah Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Abdimas Paspama Jurnal Bioteknologi & Biosains Indonesia Journal of Advanced Pharmaceutical Research Sciences and Sustainability Jurnal Pengabdian Inovatif Multidisipliner Fundamental and Applied Research in Medicine and Allied Sciences Indonesia Profixa: International Journal of Economic and Business Research
Yuneka Saristiana
Prodi Pendidikan Profesi Apoteker, Fakultas Ilmu Kesehatan, Universitas Kadiri
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Pharmacy Philosophy in the Law of Power: The Morality of Pharmaceutical Ethics towards Rhetoric of Logic Hakim, Adiyansyah Lukman; Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Mildawati, Ratna; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7595

Abstract

Pharmacy's evolution relies on technical and philosophical aspects. Research delves into the intricate link between pharmaceutical philosophy and legal power, emphasizing moral values in daily practice. The study aims to enhance policies, regulatory frameworks, and awareness, optimizing pharmacy's pivotal role in healthcare services. The results of this study depict an investigation and comprehension of the close interconnection between the philosophy of pharmacy, the law of power, the morality of pharmaceutical ethics, and rhetorical logic. A profound integration of these four aspects can provide a solid foundation for the development of ethical policies, maintaining the integrity of the pharmacy profession, and maximizing benefits for society. A deeper understanding of the complexity of these relationships can help shape a more sustainable and ethical future in the field of pharmacy. The findings of this research depict the complexity of these relationships, highlighting that deep integration can provide a solid foundation for ethical policies and the sustainable future of pharmacy
The Comparative Effectiveness of Angiotensin II Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors in Outpatient Hypertensive Patients at Community Health Centers Prasetyawan, Fendy; Yuneka Saristiana; Faisal Akhmal Muslikh; Wisnu Haryo Widyoko; Chandra Arifin; Abd Rofiq
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 3 (2024): January 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v2i1.8346

Abstract

Hypertension, often termed "The Silent Disease" due to its asymptomatic nature, remains a global health concern. This study investigates the comparative effectiveness of Angiotensin II Receptor Blockers (ARBs) and Angiotensin-Converting Enzyme Inhibitors (ACEIs) in managing hypertension, focusing on Valsartan and Candesartan (ARBs) and Ramipril and Captopril (ACEIs). Analyzing retrospective data from Community Health Centers in Solo City, the research aims to provide nuanced insights into outpatient care scenarios. The meticulous statistical analysis, utilizing SPSS and t-tests, uncovers notable differences, particularly favoring Valsartan and Ramipril within their respective drug classes. These findings carry substantial implications for healthcare practitioners, aiding in the development of precise treatment guidelines. Understanding the comparative clinical effectiveness, safety profiles, and tolerability of ARBs and ACEIs ensures a more personalized approach to hypertension management
Exploring the Macroscopic and Microscopic Characteristics of Acalypha indica L. Simplisia Powder in the Context of Pharmabotanical Studies Saristiana, Yuneka; Anita Dwi Setyarini; Yunita Dian Permatasari; Hasriyani; Arikha Ayu Susilowati; Fendy Prasetyawan
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 3 (2024): January 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v2i1.8347

Abstract

Botanical studies form a cornerstone in pharmacy, providing insights into the therapeutic potential of medicinal plants. Acalypha indica L., commonly known as "Anting-anting," holds a significant place in traditional medicine. This research focuses on the macroscopic and microscopic analysis of Acalypha indica L. simplisia, aiming to contribute to its pharmacognostic profile and enhance the standardization of herbal formulations. The exploration encompasses its historical context, traditional uses, chemical constituents, and in vitro anti-arthritis activity. The study employs advanced tools, including optical and electron microscopes, for a comprehensive examination. The macroscopic analysis involves meticulous observation of external features, while the microscopic examination delves into cellular and tissue structures. This research aligns with contemporary pharmacognosy, bridging traditional knowledge with scientific approaches, fostering a deeper understanding of medicinal plant potential
Frekuensi Penggunaan Obat Antivirus Pada Pasien SARS-CoV-2 dengan Penyakit Ginjal Kronis di Instalasi Farmasi Rawat Inap Rumah Sakit Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati; Chandra Arifin; Abd Rofiq
Jurnal Intelek Insan Cendikia Vol. 1 No. 1 (2024): Maret 2024
Publisher : PT. Intelek Cendikiawan Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pandemi COVID-19 telah menimbulkan tantangan global yang signifikan sejak munculnya virus SARS-CoV-2 pada tahun 2020. Pengendalian penyakit ini menjadi prioritas kesehatan utama mengingat dampaknya yang luas. Indonesia juga terpengaruh dengan laporan kasus pertama COVID-19 pada Maret 2020, membutuhkan perhatian serius dalam penanganannya. Salah satu komorbiditas yang sering terjadi pada pasien COVID-19 adalah penyakit ginjal kronis (CKD), yang meningkatkan risiko komplikasi medis. Pemahaman yang lebih mendalam tentang penggunaan obat antivirus pada pasien CKD yang terinfeksi COVID-19 menjadi penting, mengingat potensi toksisitas obat dan interaksi yang mungkin terjadi. Meskipun obat antivirus seperti favipiravir dan remdesivir telah menjadi strategi penting dalam penanganan COVID-19, perhatian khusus diperlukan saat memberikannya kepada pasien CKD karena risiko akumulasi dan toksisitas yang lebih tinggi. Studi potong lintang yang dilakukan di RSUD Dr. Soedomo Trenggalek bertujuan untuk mengevaluasi penggunaan obat antivirus pada pasien COVID-19 dengan CKD. Hasilnya menunjukkan bahwa mayoritas pasien menerima favipiravir (64%) dibandingkan dengan remdesivir (36%). Namun, penggunaannya perlu disesuaikan dengan fungsi ginjal pasien untuk menghindari toksisitas. Penelitian lebih lanjut diperlukan untuk memahami perbandingan efektivitas antara kedua jenis obat antivirus ini pada pasien CKD, sehingga dapat memberikan pedoman pengobatan yang lebih tepat bagi populasi pasien yang rentan ini
Gambaran Penggunaan Obat Tunggal Antihipertensi Pada Pasien Hipertensi Di Rawat Jalan Puskesmas Octavian Ashido Nababan; Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslihk; Ratna Mildawati; Isma Oktadiana
Jurnal Intelek Insan Cendikia Vol. 1 No. 1 (2024): Maret 2024
Publisher : PT. Intelek Cendikiawan Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hipertensi merupakan kondisi yang seringkali tidak menunjukkan gejala yang jelas dan dapat menjadi faktor risiko utama untuk berbagai penyakit kardiovaskular yang serius. Pengelolaan yang efektif dari hipertensi penting untuk mencegah komplikasi jangka panjang yang berpotensi fatal. Salah satu pendekatan utama dalam pengobatan hipertensi adalah penggunaan obat antihipertensi, baik dalam bentuk tunggal maupun kombinasi, tergantung pada kebutuhan setiap pasien. Di fasilitas kesehatan tingkat primer seperti Puskesmas, manajemen hipertensi sering dilakukan melalui pemberian obat tunggal sebagai terapi awal. Namun, penting untuk memahami pola penggunaan obat tunggal antihipertensi pada pasien hipertensi di rawat jalan Puskesmas. Penelitian ini bertujuan untuk memberikan gambaran yang jelas tentang bagaimana obat tunggal antihipertensi digunakan pada pasien hipertensi di Puskesmas. Metode penelitian ini adalah studi deskriptif yang mendalam dengan pendekatan retrospektif. Data pasien hipertensi dikumpulkan dari rekam medis pasien selama bulan September 2023. Hasil penelitian menunjukkan bahwa sebagian besar pasien hipertensi cenderung menggunakan kombinasi terapi daripada obat tunggal, dengan presentase penggunaan obat tunggal sebesar 35,82% dan penggunaan obat kombinasi sebesar 64,18%. Temuan ini menegaskan pentingnya strategi terapi kombinasi dalam manajemen hipertensi, yang didukung oleh efek aditif dan sinergis dari kombinasi obat serta kemampuan untuk mengurangi risiko efek samping. Dengan demikian, penelitian ini memberikan kontribusi penting bagi pengembangan pedoman pengobatan yang lebih efektif dan individualized bagi pasien hipertensi di tingkat fasilitas rawat jalan
Prediction of Augenol in Cinnamon (Cinnamomum burmannii) Boiled as a Carminative to Overcome Floating Stomach Rika Wahyu Pujiastini; Fendy Prasetyawan; Yuneka Saristiana; M. Wahyu Ariawan; Muhammad Nurul Fadel; Emma Jayanti Besan
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 1 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i1.2

Abstract

Flatulence (meteorismus) is a common condition caused by excess gas accumulation in the digestive tract. One alternative traditional treatment to overcome this condition is the use of herbal plants, such as cinnamon (Cinnamomum burmannii). This study aims to predict the potential of eugenol, an active compound in cinnamon, as a carminative agent using an in silico approach. Data were obtained from PubChem and analyzed using PASS Online to predict its pharmacological activity. The results of the analysis showed that eugenol has a probability of activity as a carminative of 0.941 and a probability of inactivity of 0.001, indicating high potential in helping to relieve flatulence. Thus, eugenol in cinnamon has the potential as an alternative natural treatment to overcome digestive disorders, especially bloating.
Pharmacokinetic Prediction Of Apigenin From Celer (Apium Graveolens L.) Using Pkcsm Lusiana Aprillia; Fendy Prasetyawan; Yuneka Saristiana; Ratna Mildawati; Chandra Arifin; Abd Rofiq
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 1 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i1.3

Abstract

Celery (Apium graveolensL.) is a plant that has various pharmacological activities. One of the main bioactive compounds in celery is apigenin. Understanding the pharmacokinetic properties of apigenin is very important in evaluating its effectiveness and safety as a drug candidate. This study aims to predict the pharmacokinetic properties of apigenin using the pkCSM computational approach. The prediction results show that apigenin has good intestinal absorption, but low water solubility. Distribution ability is moderate, with limited penetration into the central nervous system. Apigenin is not a major substrate of CYP2D6 and CYP3A4 enzymes, but can inhibit CYP1A2 and CYP3A4. The elimination rate is moderate. Apigenin is not mutagenic, not hepatotoxic, and does not cause cardiotoxic effects. Apigenin has low toxicity toT. pyriformisand safe in acute doses with an LD50 of 2,432 log mM.
PREVENTION OF GASTROPROTECTIVE ACTIVITY OF CHINESE BETEL EXTRACT (PEPEROMIA PELLUCIDA L.) ON THE HISTOPATHOLOGICAL FEATURES OF THE STOMACH IN A MOUSE MODEL OF GASTROENTERITIS Savitri, Lisa; Prasetyawan, Fendy; Saristiana, Yuneka; Juwita, Syntia Tanu; Amanda, Cornelia; Mebung, Konradus Klala
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.8156

Abstract

Gastroenteritis is a common gastrointestinal disorder characterized by inflammation of the stomach and small intestine, often leading to symptoms such as diarrhea, vomit-ing, and abdominal pain. This study investigates the gastroprotective effects of Pepe-romia pellucida (Chinese betel) extract on histopathological features of the stomach in a mouse model of gastroenteritis. Male Swiss strain mice, aged 2-3 months, were treated with different doses of P. pellucida extract (100, 300, and 500 mg/kg BW) for 7 days after inducing gastroenteritis with Escherichia coli infection. Histopathological ex-amination showed that the extract significantly reduced cell degeneration, necrosis, and polymorphonuclear leukocyte infiltration in the stomach compared to the negative control group. The highest dose (500 mg/kg BW) exhibited the most prominent gastro-protective effect. These results suggest that P. pellucida possesses promising thera-peutic potential for gastroenteritis, possibly due to its bioactive compounds such as flavonoids, tannins, and saponins. Further studies are needed to explore the underly-ing mechanisms and optimize its therapeutic application.
ANALISIS KANDUNGAN FORMALIN DAN BORAKS PADA BUMBU GILING YANG DIJUAL DI PASAR AJIBARANG WETAN mildawati, ratna; Khumaini, Eko Hidayaturrohman; Prasetyawan, Fendy; Saristiana, Yuneka
PHARMACON Vol. 14 No. 3 (2025): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.14.2025.61687

Abstract

Ground spices are a key ingredient used as food additives in almost every dish, whether at home or in places that sell various types of food. The use of food additives (BTP) in food production processes needs to be closely monitored. Additives that are prohibited include formalin and borax. Formalin and borax are banned because they can cause damage to the brain, liver, and kidneys, and long-term use can result in death. This study aims to determine whether formalin and borax are present in ground spices sold at Ajibarang Wetan Market. The ground spice samples examined came from two vendors: Vendor A (garlic, galangal, ginger, candlenut, red chili, turmeric, mixed spices, and coriander) and Vendor B (shallots, garlic, turmeric, red chili, candlenut, and mixed spices). The ground spice samples sold by Vendor A and Vendor B tested negative for both formalin and borax. The method used involved color reaction tests. To detect formalin, a potassium permanganate (KMnO₄) color reaction was used, and to detect borax, turmeric paper was employed. The conclusion of this study is that the borax test results for both vendors (Vendor A and Vendor B) were negative, as there was no color change to orange or reddish-brown. The formalin test results for both vendors were also negative, as there was no change in color to clear.
Kombucha Tea as a Health Alternative in the Context of Quantum Entanglement in the Era of the COVID-19 Pandemic in the Pharmaceutical Context Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Asrizal Azis; Ema Tri Wulan; Ratna Mildawati
Abdimas Paspama Vol. 2 No. 02 (2024): Abdimas Paspama, June 2024
Publisher : Abdimas Paspama

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In the midst of the COVID-19 pandemic, exploring innovative health alternatives becomes imperative. This study delves into the role of Kombucha Tea as a promising health option within the framework of quantum entanglement. Kombucha, a fermented beverage with roots in various cultures, offers a plethora of health benefits. Through community engagement efforts conducted in 2021, we aimed to raise awareness about Kombucha Tea and its significance in fostering holistic health amidst the pandemic. The socialization activities encompassed informative sessions, practical workshops, and training programs to disseminate knowledge and empower individuals regarding Kombucha Tea. These initiatives aimed to highlight the intricate relationship between individuals, their environment, and overall well-being, underpinned by the concept of quantum entanglement. The sessions provided insights into the fermentation process of Kombucha Tea, its health benefits, and practical tips for its integration into daily lifestyles. Results indicated a high level of interest among participants in Kombucha Tea as an alternative health option. The sessions fostered a deeper understanding of its health benefits, particularly in enhancing immune function and digestive health. Moreover, participants expressed enthusiasm for incorporating Kombucha Tea into their daily routines. The program's success was further evidenced by the positive feedback received from both participants and community leaders. The interactive nature of the workshops and the informative materials distributed contributed to enhancing public awareness and understanding of Kombucha Tea's potential contributions to health.
Co-Authors Abd Rofiq Abd Rofiq Achmad Wahdi Achmad Wahdi Adiyansyah Lukman Hakim Akhmal, Faisal Ali Anhar Syi’bul Huda Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anggun Wida Prawira Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arsiaty Sumule Ary Kristijono Asrizal Azis Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Ema Jayanti Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Chandra Arifin Charliandri Saputra Wahab Cornelia Amanda Dara Sukma Ratmelya Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Edda, Ilda Rambu Eka Hayati Rhomah Eka Hayati Rhomah Eka Nur Fatmawati Eka Nur Fatmawati Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo, Elfred Rinaldo Elly Rachmawati Ratnaningrum Elsa Mahardika Putri Elsa Mahardika Putri Ema Tri Wulan Ema Tri Wulan Emma Jayanti Besan Emma Jayanti Besan Faisal Akhmal Muslihk Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hakim, Adiyansyah Lukman Hartini, Putri Tri Hasriyani Hasriyani Hasriyani Hasriyani Hasriyani, Hasriyani Herman Herman Herman Husnunnisa Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Imam Agus Faizal Imran, Arlan K Indrayanti, Dian Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kharisul Ihsan Kholis, Muhammad Akbar Nur Khumaini, Eko Hidayaturrohman Konradus Klala Mebung Kristjono, Ary Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lisa Savitri Lisa Savitri Lusiana Aprillia M Wahyu Ariawan M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri, Meri Meri, Meri milda, ratna Mildawati, Ratna Mohammad Firdaus Alshol Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Mujtahid Bin Abd. Kadir Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Nur Masyithah Zamruddin Octavian Ashido Nababan Okky Intan Mawarni Okky Intan Mawarni Oktadiana, Isma Prasetyo Nugroho, Bandhi prayoga fery yuniarto Probosiwi , Neni Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Wati Ratna Mildwati Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda Shinta Mayasari Shinta Mayasari Sugeng Santoso Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Widhi Astutik Widhi Astutik Widhi Astutik Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Yunita Dian Permatasari Zahra, Ilhawa Ziza Putri Aisyia Fauzi