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All Journal PHARMACON Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Well Being Jumat Ekonomi: Jurnal Pengabdian Masyarakat PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Hasil Inovasi Masyarakat (JHIM) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara Jurnal Cendekia Ilmiah Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Abdimas Paspama Jurnal Bioteknologi & Biosains Indonesia Journal of Advanced Pharmaceutical Research Sciences and Sustainability Jurnal Pengabdian Inovatif Multidisipliner
Yuneka Saristiana
Prodi Pendidikan Profesi Apoteker, Fakultas Ilmu Kesehatan, Universitas Kadiri
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Utilization of Antiviral Medications in COVID-19 Patients with Chronic Kidney Disease in Hospital Saristiana, Yuneka; Prasetyawan, Fendy; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Mildawati, Ratna; Putri, Elsa Mahardika; Raharjo, Susilo Margining
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i1.7284

Abstract

The COVID-19 pandemic has presented a substantial global health challenge, affecting diverse patient populations, particularly those with chronic kidney disease. Hospitals are presently dependent on two antiviral medications, favipiravir and remdesivir, to mitigate the impact of this disease on patients with chronic kidney disease. This study aims to evaluate the utilization of favipiravir and remdesivir in COVID-19 patients with chronic kidney disease in a hospital setting. This research will employ a retrospective approach to gather data from the medical records of COVID-19 patients with chronic kidney disease who received treatment with favipiravir or remdesivir in the hospital. Considering the prevalence of favipiravir usage at 64% and remdesivir at 36%, this research aims to provide a comprehensive understanding of the effectiveness and associated risks of toxicity linked to these two medications in COVID-19 patients with chronic kidney disease
Farmakoantartika Literature Study: Bioactivity of Pagodroma nivea on Fossil Deposits from Mujito Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Raharjo, Susilo Margining; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7593

Abstract

This report investigates the biodiversity of marine animals, focusing on extinct sponge species near Lesbos Island based on Aristotle's descriptions. Mujito, introduced in the literature review, is from the GeoMaud expedition in Antarctica. Various instrumental analysis methods, such as ESI mass spectrometry and NMR, contribute to a comprehensive understanding of the compounds, particularly in the context of Alzheimer's research. The pharmacantarctic literature study concludes that Antarctic Mumijo, particularly from Mujito fossil deposits, holds significant biomedical potential. It exhibits organic components like wax esters with notable biomedical activities, particularly in treating bone diseases. Additionally, Mumijo's composition resembles non-fossil samples, with wax esters dominating and unique components like α-glyceryl fatty alcohol ethers indicating neuroprotective potential. The research suggests promising applications in Oriental medicine, addressing wounds, skin diseases, tuberculosis, respiratory diseases, and neurological conditions like Parkinson's and Alzheimer's. Overall, Antarctic Mumijo showcases diverse biomedical prospects, emphasizing its organic components' therapeutic value
Forensic Pharmacy Case Study: Identification of Hazardous Mercury Content as a Whitening Agent in Beauty Cream Products Ardianto, Nanda; Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Mildawati, Ratna; Dhafin, Anis Akhwan; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7594

Abstract

Forensic pharmacy is crucial in identifying hazardous substances like mercury in beauty products. Counterfeit items with mercury pose health risks, emphasizing the need for accurate identification methods. The research, employing content analysis, focuses on illegal cosmetics containing mercury, aiming to understand distribution patterns and assess associated health risks. This systematic approach provides valuable insights into public health issues, contributing to safer regulatory practices. The utilization of these products may pose serious health risks to consumers. The implicated products include Temulawak New Day & Night, CAC Glow, Natural 99, HN (Day & Night), SP Special UV Whitening, Dr Original Pemutih, Super DR Quality Gold SPF 30, Diamond Cream, Herbal Plus New Day & Night, Ling Zhi Day & Night, Sj Sin Jung, Tabita, and Krim Labella. In Indonesia, the use of mercury in cosmetic products is prohibited by legislation, such as Law Number 32 of 2009 on Environmental Protection and Government Regulation of the Republic of Indonesia Number 81 of 2016 on the Security of Industrial Chemicals. Additionally, BPOM, responsible for overseeing drugs, food, and cosmetics, has issued relevant regulations
Pharmacy Philosophy in the Law of Power: The Morality of Pharmaceutical Ethics towards Rhetoric of Logic Hakim, Adiyansyah Lukman; Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Mildawati, Ratna; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7595

Abstract

Pharmacy's evolution relies on technical and philosophical aspects. Research delves into the intricate link between pharmaceutical philosophy and legal power, emphasizing moral values in daily practice. The study aims to enhance policies, regulatory frameworks, and awareness, optimizing pharmacy's pivotal role in healthcare services. The results of this study depict an investigation and comprehension of the close interconnection between the philosophy of pharmacy, the law of power, the morality of pharmaceutical ethics, and rhetorical logic. A profound integration of these four aspects can provide a solid foundation for the development of ethical policies, maintaining the integrity of the pharmacy profession, and maximizing benefits for society. A deeper understanding of the complexity of these relationships can help shape a more sustainable and ethical future in the field of pharmacy. The findings of this research depict the complexity of these relationships, highlighting that deep integration can provide a solid foundation for ethical policies and the sustainable future of pharmacy
The Comparative Effectiveness of Angiotensin II Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors in Outpatient Hypertensive Patients at Community Health Centers Prasetyawan, Fendy; Yuneka Saristiana; Faisal Akhmal Muslikh; Wisnu Haryo Widyoko; Chandra Arifin; Abd Rofiq
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 3 (2024): January 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v2i1.8346

Abstract

Hypertension, often termed "The Silent Disease" due to its asymptomatic nature, remains a global health concern. This study investigates the comparative effectiveness of Angiotensin II Receptor Blockers (ARBs) and Angiotensin-Converting Enzyme Inhibitors (ACEIs) in managing hypertension, focusing on Valsartan and Candesartan (ARBs) and Ramipril and Captopril (ACEIs). Analyzing retrospective data from Community Health Centers in Solo City, the research aims to provide nuanced insights into outpatient care scenarios. The meticulous statistical analysis, utilizing SPSS and t-tests, uncovers notable differences, particularly favoring Valsartan and Ramipril within their respective drug classes. These findings carry substantial implications for healthcare practitioners, aiding in the development of precise treatment guidelines. Understanding the comparative clinical effectiveness, safety profiles, and tolerability of ARBs and ACEIs ensures a more personalized approach to hypertension management
Exploring the Macroscopic and Microscopic Characteristics of Acalypha indica L. Simplisia Powder in the Context of Pharmabotanical Studies Saristiana, Yuneka; Anita Dwi Setyarini; Yunita Dian Permatasari; Hasriyani; Arikha Ayu Susilowati; Fendy Prasetyawan
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 3 (2024): January 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v2i1.8347

Abstract

Botanical studies form a cornerstone in pharmacy, providing insights into the therapeutic potential of medicinal plants. Acalypha indica L., commonly known as "Anting-anting," holds a significant place in traditional medicine. This research focuses on the macroscopic and microscopic analysis of Acalypha indica L. simplisia, aiming to contribute to its pharmacognostic profile and enhance the standardization of herbal formulations. The exploration encompasses its historical context, traditional uses, chemical constituents, and in vitro anti-arthritis activity. The study employs advanced tools, including optical and electron microscopes, for a comprehensive examination. The macroscopic analysis involves meticulous observation of external features, while the microscopic examination delves into cellular and tissue structures. This research aligns with contemporary pharmacognosy, bridging traditional knowledge with scientific approaches, fostering a deeper understanding of medicinal plant potential
Frekuensi Penggunaan Obat Antivirus Pada Pasien SARS-CoV-2 dengan Penyakit Ginjal Kronis di Instalasi Farmasi Rawat Inap Rumah Sakit Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati; Chandra Arifin; Abd Rofiq
Jurnal Intelek Insan Cendikia Vol. 1 No. 1 (2024): Maret 2024
Publisher : PT. Intelek Cendikiawan Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pandemi COVID-19 telah menimbulkan tantangan global yang signifikan sejak munculnya virus SARS-CoV-2 pada tahun 2020. Pengendalian penyakit ini menjadi prioritas kesehatan utama mengingat dampaknya yang luas. Indonesia juga terpengaruh dengan laporan kasus pertama COVID-19 pada Maret 2020, membutuhkan perhatian serius dalam penanganannya. Salah satu komorbiditas yang sering terjadi pada pasien COVID-19 adalah penyakit ginjal kronis (CKD), yang meningkatkan risiko komplikasi medis. Pemahaman yang lebih mendalam tentang penggunaan obat antivirus pada pasien CKD yang terinfeksi COVID-19 menjadi penting, mengingat potensi toksisitas obat dan interaksi yang mungkin terjadi. Meskipun obat antivirus seperti favipiravir dan remdesivir telah menjadi strategi penting dalam penanganan COVID-19, perhatian khusus diperlukan saat memberikannya kepada pasien CKD karena risiko akumulasi dan toksisitas yang lebih tinggi. Studi potong lintang yang dilakukan di RSUD Dr. Soedomo Trenggalek bertujuan untuk mengevaluasi penggunaan obat antivirus pada pasien COVID-19 dengan CKD. Hasilnya menunjukkan bahwa mayoritas pasien menerima favipiravir (64%) dibandingkan dengan remdesivir (36%). Namun, penggunaannya perlu disesuaikan dengan fungsi ginjal pasien untuk menghindari toksisitas. Penelitian lebih lanjut diperlukan untuk memahami perbandingan efektivitas antara kedua jenis obat antivirus ini pada pasien CKD, sehingga dapat memberikan pedoman pengobatan yang lebih tepat bagi populasi pasien yang rentan ini
Gambaran Penggunaan Obat Tunggal Antihipertensi Pada Pasien Hipertensi Di Rawat Jalan Puskesmas Octavian Ashido Nababan; Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslihk; Ratna Mildawati; Isma Oktadiana
Jurnal Intelek Insan Cendikia Vol. 1 No. 1 (2024): Maret 2024
Publisher : PT. Intelek Cendikiawan Nusantara

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Abstract

Hipertensi merupakan kondisi yang seringkali tidak menunjukkan gejala yang jelas dan dapat menjadi faktor risiko utama untuk berbagai penyakit kardiovaskular yang serius. Pengelolaan yang efektif dari hipertensi penting untuk mencegah komplikasi jangka panjang yang berpotensi fatal. Salah satu pendekatan utama dalam pengobatan hipertensi adalah penggunaan obat antihipertensi, baik dalam bentuk tunggal maupun kombinasi, tergantung pada kebutuhan setiap pasien. Di fasilitas kesehatan tingkat primer seperti Puskesmas, manajemen hipertensi sering dilakukan melalui pemberian obat tunggal sebagai terapi awal. Namun, penting untuk memahami pola penggunaan obat tunggal antihipertensi pada pasien hipertensi di rawat jalan Puskesmas. Penelitian ini bertujuan untuk memberikan gambaran yang jelas tentang bagaimana obat tunggal antihipertensi digunakan pada pasien hipertensi di Puskesmas. Metode penelitian ini adalah studi deskriptif yang mendalam dengan pendekatan retrospektif. Data pasien hipertensi dikumpulkan dari rekam medis pasien selama bulan September 2023. Hasil penelitian menunjukkan bahwa sebagian besar pasien hipertensi cenderung menggunakan kombinasi terapi daripada obat tunggal, dengan presentase penggunaan obat tunggal sebesar 35,82% dan penggunaan obat kombinasi sebesar 64,18%. Temuan ini menegaskan pentingnya strategi terapi kombinasi dalam manajemen hipertensi, yang didukung oleh efek aditif dan sinergis dari kombinasi obat serta kemampuan untuk mengurangi risiko efek samping. Dengan demikian, penelitian ini memberikan kontribusi penting bagi pengembangan pedoman pengobatan yang lebih efektif dan individualized bagi pasien hipertensi di tingkat fasilitas rawat jalan
Prediction of Augenol in Cinnamon (Cinnamomum burmannii) Boiled as a Carminative to Overcome Floating Stomach Rika Wahyu Pujiastini; Fendy Prasetyawan; Yuneka Saristiana; M. Wahyu Ariawan; Muhammad Nurul Fadel; Emma Jayanti Besan
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 1 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i1.2

Abstract

Flatulence (meteorismus) is a common condition caused by excess gas accumulation in the digestive tract. One alternative traditional treatment to overcome this condition is the use of herbal plants, such as cinnamon (Cinnamomum burmannii). This study aims to predict the potential of eugenol, an active compound in cinnamon, as a carminative agent using an in silico approach. Data were obtained from PubChem and analyzed using PASS Online to predict its pharmacological activity. The results of the analysis showed that eugenol has a probability of activity as a carminative of 0.941 and a probability of inactivity of 0.001, indicating high potential in helping to relieve flatulence. Thus, eugenol in cinnamon has the potential as an alternative natural treatment to overcome digestive disorders, especially bloating.
Pharmacokinetic Prediction Of Apigenin From Celer (Apium Graveolens L.) Using Pkcsm Lusiana Aprillia; Fendy Prasetyawan; Yuneka Saristiana; Ratna Mildawati; Chandra Arifin; Abd Rofiq
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 1 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i1.3

Abstract

Celery (Apium graveolensL.) is a plant that has various pharmacological activities. One of the main bioactive compounds in celery is apigenin. Understanding the pharmacokinetic properties of apigenin is very important in evaluating its effectiveness and safety as a drug candidate. This study aims to predict the pharmacokinetic properties of apigenin using the pkCSM computational approach. The prediction results show that apigenin has good intestinal absorption, but low water solubility. Distribution ability is moderate, with limited penetration into the central nervous system. Apigenin is not a major substrate of CYP2D6 and CYP3A4 enzymes, but can inhibit CYP1A2 and CYP3A4. The elimination rate is moderate. Apigenin is not mutagenic, not hepatotoxic, and does not cause cardiotoxic effects. Apigenin has low toxicity toT. pyriformisand safe in acute doses with an LD50 of 2,432 log mM.
Co-Authors Abd Rofiq Abd Rofiq Achmad Wahdi Achmad Wahdi Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Akhmal, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arsiaty Sumule Ary Kristijono Asrizal Azis Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Ema Jayanti Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Chandra Arifin Charliandri Saputra Wahab Cornelia Amanda Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Edda, Ilda Rambu Eka Hayati Rhomah Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo, Elfred Rinaldo Elly Rachmawati Ratnaningrum Elsa Mahardika Putri Elsa Mahardika Putri Ema Tri Wulan Ema Tri Wulan Emma Jayanti Besan Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hakim, Adiyansyah Lukman Hasriyani Hasriyani Hasriyani, Hasriyani Herman Herman Herman Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Imam Agus Faizal Imran, Arlan K Indrayanti, Dian Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kharisul Ihsan Kholis, Muhammad Akbar Nur Khumaini, Eko Hidayaturrohman Konradus Klala Mebung Kristjono, Ary Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lisa Savitri Lusiana Aprillia M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri Meri Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Mohammad Firdaus Alshol Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Okky Intan Mawarni Oktadiana, Isma Prasetyo Nugroho, Bandhi Prayoga Fery Yuniarto Probosiwi , Neni Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda Shinta Mayasari Shinta Mayasari Sugeng Santoso Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Widhi Astutik Widhi Astutik Widhi Astutik Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Zahra, Ilhawa