Claim Missing Document
Check
Articles

Chemical Structure Profile and Computational Descriptors of Fenbufen Butanamine by PubChem Yuneka Saristiana; Fendy Prasetyawan; Ratna Mildawati; Yogi Bhakti Marhenta; Eka Hayati Rhomah; Mujtahid Bin Abd Kadir
Jurnal Kajian dan Inovasi Ilmu (JKII) Vol. 1 No. 2 (2025): November
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/jkii.v1.i2.2

Abstract

Fenbufen Butanamine is a structural derivative of the non-steroidal anti-inflammatory drug (NSAID) Fenbufen, characterized by the addition of a butanamine group to its core structure. This modification is intended to improve the pharmacokinetic and pharmacodynamic properties of the parent compound, potentially enhancing its therapeutic efficacy. In this study, we conducted a detailed computational analysis of Fenbufen Butanamine’s chemical structure and molecular descriptors using data retrieved from the PubChem database. The chemical identity was confirmed by its IUPAC name, InChI, InChIKey, and SMILES notation, which provide precise molecular characterization essential for database referencing and further computational modeling. Key computational descriptors, such as molecular weight, logP, topological polar surface area (TPSA), and the count of hydrogen bond donors and acceptors, were analyzed to assess drug-likeness and predict pharmacokinetic behavior. Our findings indicate that Fenbufen Butanamine possesses a biphenyl core that contributes to hydrophobic interactions, while the butanamine side chain introduces hydrophilic properties. This amphiphilic nature is likely to influence the compound’s solubility, membrane permeability, and binding affinity to biological targets. The computed descriptors suggest favorable properties for oral bioavailability and potential interactions within biological systems. These results serve as a foundational step for in silico drug design and optimization of Fenbufen derivatives. Further experimental and pharmacological studies are warranted to validate these computational predictions and explore the therapeutic potential of Fenbufen Butanamine. 
Training on Oral Drug Administration in Test Animals as an Effort to Strengthen Pharmacology Practicum Competence Prasetyawan, Fendy; Saristiana, Yuneka; Salmasfattah, Novynanda; Alshol, Mohammad Firdaus
Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) Vol. 1 No. 1 (2025): Maret
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mjpmm.v1.i1.4

Abstract

Training in the skill of administering oral medication to test animals is a form of community service aimed at enhancing pharmacy students' competencies in pharmacology laboratory practices. This activity will take place on May 19, 2025, in the Pharmacology Laboratory at Kadiri University. It will consist of direct training that includes theoretical presentations, demonstrations, and independent practice by students, accompanied by guidance from instructors and laboratory staff. The materials presented include the anatomy of the mouse digestive system, the basic principles of oral gavage, the ethics of using test animals, and safety aspects. The evaluation results indicate that this training has enhanced the participants' understanding of oral gavage techniques as well as their skills in performing the procedure safely and accurately. Based on the comparison of pretest and posttest scores, as well as practical observations, there is a significant improvement in the technical skills and ethical attitudes of the students. This training also enhances the understanding of the importance of animal welfare in pharmacological experiments. This activity is expected to serve as a sustainable model for enhancing the quality of practical learning in the field of pharmacy education.
Interactive Discussion Related to the Preparation of Pharmacy Professional Work Practice at the Health Center and Health Office Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Marhenta, Yogi Bhakti; Kadir, Mujtahid Bin Abd; Arifin, Chandra; Rofiq, Abd; Astutik, Widhi; Rohmah, Eka Hayati
Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) Vol. 1 No. 1 (2025): Maret
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mjpmm.v1.i1.3

Abstract

The Professional Pharmacy Practice Experience (PKPA) at Community Health Centers and Health Offices plays a crucial role in developing the professional competence of pharmacy students before they enter the actual workforce. To facilitate this preparation, an interactive discussion activity has been conducted as a means of training and collective reflection among students, supervising lecturers, and resource persons from the Health Office and community health centers. This discussion aims to enhance students' understanding of the roles and responsibilities of pharmacists within primary healthcare facilities (FKTP), while also identifying the challenges and solutions involved in the implementation of PKPA. The execution of the discussion demonstrated a high level of enthusiasm among students in exploring both the technical and non-technical aspects of the pharmacy profession, including the integration of clinical and managerial roles. The evaluation of the questionnaire reveals that over 85% of participants believe this activity significantly aids in preparing them to confront the PKPA with greater confidence. Group discussions highlight the significance of interpersonal communication skills, professional ethics, and teamwork collaboration as essential factors for the success of practice. A representative from the Health Department assessed that this activity is effective in aligning the perspectives between educational institutions and practical venues, thereby fostering ongoing synergy.
Peningkatan Pengetahuan Masyarakat tentang Beyond Use Dates (BUD) Obat melalui Edukasi di Acara Apothecary Fun Run 2025 Saristiana, Yuneka; Prasetyawan, Fendy; Herman
Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) Vol. 1 No. 2 (2025): September
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mjpmm.v1.i2.5

Abstract

Beyond Use Dates (BUD) obat merupakan informasi penting terkait batas waktu keamanan penggunaan obat setelah kemasan dibuka atau sediaan dibuat, yang seringkali belum dipahami secara optimal oleh masyarakat. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan publik mengenai BUD melalui edukasi interaktif pada acara Apothecary Fun Run 2025 yang diselenggarakan Ikatan Apoteker Indonesia (IAI) di Stadion Menak Sopal, Trenggalek, pada 10 Agustus 2025. Metode kegiatan meliputi presentasi visual, diskusi interaktif, simulasi penandaan BUD pada kemasan obat, serta pembagian leaflet informasi. Evaluasi dilakukan menggunakan pre-test dan post-test, disertai survei kepuasan peserta. Hasil menunjukkan peningkatan skor pengetahuan rata-rata dari 54,3 menjadi 88,5 poin, dengan persentase pemahaman konsep BUD naik dari 40% menjadi 92%. Tingkat kepuasan peserta sangat tinggi, dengan 94% menyatakan “Sangat Memuaskan” atau “Memuaskan”. Edukasi interaktif berbasis praktik nyata terbukti efektif dalam meningkatkan literasi kesehatan terkait keamanan obat. Program ini direkomendasikan untuk diimplementasikan secara berkelanjutan dalam kegiatan komunitas, guna meminimalkan risiko penggunaan obat yang sudah melewati BUD. 
The Kombucha sebagai Alternatif Kesehatan dalam Konteks Quantum Entanglement di Era Pandemi COVID-19 Konteks Farmasi Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Azis, Asrizal; Wulan, Ema Tri
Journal of Social and Community Service Vol. 1 No. 3 (2022): July 2022
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v2i2.148

Abstract

In the challenging era of the COVID-19 pandemic, it becomes crucial to explore innovative health alternatives. Through community engagement, we highlight the role of Kombucha Tea as an intriguing health option, particularly within the context of quantum entanglement. Kombucha, a fermented beverage deeply rooted in various cultures, offers a spectrum of health benefits. In 2021, we conducted a series of socialization activities to disseminate knowledge about Kombucha Tea and underscore the importance of the holistic relationship between individuals, their environment, and health. Through informative sessions, practical workshops, and training programs, our objective was to enhance public awareness regarding the potential of Kombucha Tea in improving overall well-being.
Sosialisasi Tingkat Kesadaran dan Pengetahuan Masyarakat Tentang Manfaat Teh Kombucha Dalam Mengatasi Sleep Paralysis Selama Pandemi COVID-19 Saristiana, Yuneka; Prasetyawan, Fendy; Arifin, Chandra; Rofiq, Abd; Astutik, Widhi; Azis, Asrizal; Tri Wulan, Ema
Journal of Social and Community Service Vol. 1 No. 3 (2022): July 2022
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v1i3.149

Abstract

This community service program aims to enhance public understanding and knowledge about sleep paralysis and the benefits of kombucha tea during the COVID-19 pandemic. Conducted throughout January 2021, the program involved various socialization activities such as presentations, workshops, and discussions. Post-activity evaluations showed a significant improvement in public understanding of sleep paralysis and the benefits of kombucha tea. Prior to the program, most respondents had limited knowledge about sleep paralysis and kombucha tea, but after participating, their understanding increased significantly. Despite facing some challenges, the overall results of this program indicate that socialization about sleep paralysis and the benefits of kombucha tea can be effective in enhancing public understanding of sleep health and nutrition during the COVID-19 pandemic.
Community Empowerment Through Increasing Knowledge About the Truth of the Drug NZT-48 as a Neurotrophic in Increasing Brain Potential: Pengabdian Masyarakat Melalui Peningkatan Pengetahuan Tentang Kebenaran Obat NZT-48 sebagai Neurotropik dalam Meningkatkan Potensi Otak Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Arifin, Chandra; Rofiq, Abd; Astutik, Widhi
Journal of Social and Community Service Vol. 3 No. 3 (2024): November 2024
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v3i3.196

Abstract

The community service aimed to bridge the gap between scientific knowledge and public perception regarding nootropics. Through a comprehensive approach involving meticulous planning, community engagement, educational activities, expert consultations, feedback collection, and evaluation, the program sought to increase awareness and understanding of cognitive enhancement substances among participants. Real-life case studies and guest lectures by renowned experts enriched the learning experience, addressing scientific, ethical, and social perspectives. The proactive involvement of community leaders and an effective awareness campaign ensured high participation and relevance. It underscored the importance of a multidisciplinary approach in addressing complex topics and highlighted the value of engaging communities in meaningful discussions about health and well-being. The program not only educated the community about the realities and myths surrounding NZT-48 and other nootropics but also promoted critical thinking and informed decision- making. By empowering the community with accurate information and fostering a culture of informed skepticism, the program contributed to the betterment of community health and well-being, setting a precedent for future public health education initiatives.
Co-Authors Abd Rofiq Abd Rofiq Abd Rofiq Abd Rofiq Achmad Wahdi Adiyansyah Lukman Hakim Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Anita Dwi Setyarini Arifani Siswidiasari Arikha Ayu Susilowati Arsiaty Sumule Ary Kristijono Ary Kristijono Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Bandhi Prasetya Nugroho Besan, Emma Jayanti Candra Arifin Chandra Arifin Chandra Arifin Chandra Arifin Chandra Arifin Charliandri Saputra Wahab Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Edda, Ilda Rambu Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo, Elfred Rinaldo Elsa Mahardika Putri Elsa Mahardika Putri Ema Jayanti Besan Ema Tri Wulan Emma Jayanti Besan Faisal Akhmal Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hasriyani Hasriyani Hasriyani, Hasriyani Herman Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Ilhawa Zahra Imran, Arlan K Indrayanti, Dian Isma Oktadiana Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kholis, Muhammad Akbar Nur Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lusiana Aprillia M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Nanda Ardianto Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Octavian Ashido Nababan Okky Intan Mawarni Oktadiana, Isma Prayoga Fery Yuniarto Probosiwi , Neni Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Ratna Mildawati Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda savitri, Lisa Shinta Mayasari Shinta Mayasari Sugeng, Santoso Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Wahyu Ariawan Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Yunita Dian Permatasari