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All Journal Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Well Being PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara J-CEKI Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Journal Abdimas Paspama Service Jurnal Bioteknologi & Biosains Indonesia
Yuneka Saristiana
Prodi Pendidikan Profesi Apoteker, Fakultas Ilmu Kesehatan, Universitas Kadiri
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Increasing Awareness Among Teenagers About Preventing Non-Communicable Diseases Through The Use Of Multimedia At Karang Taruna Wates Bandhi Prasetya Nugroho; milda, ratna; Fendy Prasetyawan; Baarik Lana Fadli; Yuneka Saristiana; Isma Oktadiana; Arsiaty Sumule
Amaluna: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2024)
Publisher : Institut Agama Islam Negeri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/amaluna.v3i1.3408

Abstract

Non-Communicable Diseases (NCDs) are currently a serious health problem in the world, because these diseases are one of the most common causes of death. Community empowerment in preventing PTM through community components, one of which is youth organizations or youth organizations which have an important role in taking part, is expected to be able to prevent PTM through various more interesting media. The aim of this community service is to provide PTM education through the use of multimedia. The method used is to convey information accompanied by posters, pictures and discussions. After providing education, it is hoped that youth organizations will be able to be more critical about PTM and be able to provide further education to the wider community, especially in the Wates area, by utilizing multimedia. Keywords: Non-communicable diseases, Karang Taruna, Multimedia
Education about worms through animated videos for early childhood Ana Amalia; milda, ratna; Fendy Prasetyawan; Yuneka Saristiana; Isma Oktadiana; Arsiaty Sumule
Amaluna: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2024)
Publisher : Institut Agama Islam Negeri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/amaluna.v3i1.3431

Abstract

This worm disease can infect all ages, but those who are most susceptible to infection are children under five and elementary school age (SD) aged 5 to 14 years. To be able to break the chain of worm infections and reduce the number of worm infections in schools, this can be done by providing information or education. Providing education about worms can increase students' knowledge regarding preventing worms. The aim of this activity is to increase the knowledge of students and girls in preventing worms. The method of this service is to provide education using animated video media about worm disease and hand washing demonstrations. After counseling and demonstrations, the results of the education that has been provided will be evaluated using a questionnaire to evaluate students' knowledge of worms and their prevention after 1 week of providing counseling via educational video media. The results of the activity showed an increase in knowledge and psychomotor skills after being given education regarding worms and washing hands. It is hoped that increasing understanding of the dangers of worms can foster awareness and independence in preventing worms in families and communities. Keywords: Worms, education, animated video
Protective Role of Paederia foetida L. Against Hepatic Inflammatory Response in a Mice Model of Escherichia coli-Induced Sepsis Savitri, Lisa; Freitas, Maria Do Carmo Da Costa; Prasetyawan, Fendy; Saristiana, Yuneka; Mebung, Konradus Klala; Amanda, Cornelia
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.363-368

Abstract

Sepsis is a severe medical condition characterized by a systemic immune response to infection, often leading to multi-organ failure and death if not treated effectively. This study aimed to investigate the antiseptic properties of Paederia foetida leaf extract in male mice induced with sepsis using Escherichia coli. A total of 24 mice were divided into six groups: a normal group (no treatment), a negative control group (distilled water), a positive control group (ciprofloxacin), and three treatment groups receiving P. foetida leaf extract at doses of 100, 300, and 500 mg/kg BW. After 15 days of oral administration, liver tissue samples were analyzed for IL-6 expression, a pro-inflammatory cytokine associated with sepsis. The results revealed a significant reduction in IL-6 expression in the treatment groups, particularly at the 500 mg/kg BW dose. This dose showed the most effective anti-inflammatory response, with IL-6 expression levels comparable to those of the positive control group treated with ciprofloxacin. However, the 100 mg/kg BW dose demonstrated minimal effects, similar to the negative control. These findings suggest that P. foetida leaf extract, especially at higher doses, has potential as an anti-inflammatory agent in sepsis management. The bioactive compounds in the extract, including flavonoids, alkaloids, and terpenoids, likely contribute to its efficacy. This study provides preliminary evidence supporting the use of P. foetida as a potential herbal alternative for managing sepsis, but further clinical research is necessary to confirm its therapeutic potential.
Edukasi Peluang Dan Tantangan Terkini Pharmacist Dengan Distruksi di Industri Farmasi Fendy Prasetyawan; Mujtahid Bin Abd Kadir; Nur Fahma Laili; Prayoga Fery Yuniarto; Datin An Nisa Sukmawati; Arifani Siswidiasari; Neni Probosiwi; Tsamrotul Ilmi; Elsa Mahardika Putri; Yuneka Saristiana; Okky Intan Mawarni; Winartiana; Nimas Ayu Rahardini; Anis Akhwan Dhafin
Khidmah Nusantara Vol. 1 No. 1 (2024): Agustus 2024
Publisher : CV.RIZANIA MEDIA PRATAMA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69533/ghy9th25

Abstract

Tingkat pengangguran yang meningkat setiap tahunnya membuat masyarakat mencari sumber informasi dengan tujuan memperoleh dan mendapatkan lapangan pekerjaan, yang dapat dicapai dengan menempuh pendidikan perguruan tinggi. Jurusan farmasi merupakan jurusan yang banyak diminati karena memiliki prospek yang biak kedepannya dan salah satu jurusan populer. Seorang farmasis dapat bekerja disektor industri, indonesia memiliki sebanyak 230 industri farmasi. Dengan jumlah industri yang banyak sehingga industri farmasi membutuhkan banyak tenaga kerja, terutama tenaga farmasi yang profesional. Selain peluang kerja di indsutri farmasi namun di era industri 4.0 ini tantangan yang dihadapi semakin besar, sehingga farmasis harus meningkatkan pengetahuan untuk mengimbangi teknologi yang terus maju. Oleh karena itu diperukan pengetahuan untuk meningkat wawasan terkait indutri farmasi.Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk mendorong mahasiswa farmasi agar dapat bekerja di industri farmasi dan memberikan gambaran tentang industri farmasi. Kegiatan pengabdian ini dilakukan di gedung AULA FIK Universitas Kadiri hari sabtu, 20 April 2024. Hasil kegiatan menunjukkan bahwa peserta antusias mengikuti acara, terlihat dari keikutsertaan mereka dalam mengikuti acara dari awal hingga akhir dan mengajukan pertanyaan selama sesi kuliah pakar berlangsung.Oleh karena itu, kegiatan pengabdian masyarakat ini dinilai berpotensi membantu menginspirasi, mendorong dan informasi bagi mahasiswa farmasi untuk berkarir di industri farmasi.
Education on the Use of Vitamin A (Retinol) for the Prevention of Myopia in Adolescents in Gembleb Trenggalek: Edukasi Penggunaan Obat Vitamin A (Retinol) Untuk Pencegahan Penyakit Miopi Pada Remaja di Dusun Gembleb Trenggalek Prasetyawan, Fendy; Saristiana, Yuneka; Salmasfattah, Novyananda; Savitri, Lisa; Herman; Kadir, Mujtahid Bin Abd
KOMUNITA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 4 No 2 (2025): Mei
Publisher : PELITA NUSA TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60004/komunita.v4i2.177

Abstract

This community service program aimed to increase adolescents' awareness and knowledge regarding the role of Vitamin A (Retinol) in preventing myopia, particularly in rural areas such as Gembleb Village, Trenggalek. The activity was conducted on Saturday, May 3, 2025, in collaboration with the Government of Gembleb Village and supported by the Institute for Research, Community Service, and Publication (LP3M) of Universitas Kadiri. A total of 15 adolescents participated in the educational intervention, which included a pre-test, a lecture session, and a post-test evaluation. The results showed a significant improvement in participants’ knowledge about myopia and the importance of Vitamin A for eye health. Pre-test scores averaged lower compared to post-test results, with an average increase of 20–25 points. This finding suggests that structured education can effectively enhance health literacy among youth, particularly regarding nutritional prevention of visual disorders. These outcomes underscore the importance of continued community-based health education programs, especially in underserved areas, as a strategic effort to reduce the prevalence of preventable eye diseases
Education on the Benefits of Red Ginger (Zingiber officinale) to Overcome Menstrual Pain in Adolescent Girls in Gembleb Trenggalek: Edukasi Manfaat Jahe Merah (Zingiber officinale) Untuk Mengatasi Nyeri Haid Pada Remaja Putri di Dusun Gembleb Trenggalek Saristiana, Yuneka; Prasetyawan, Fendy; Salmasfattah, Novyananda; Savitri, Lisa; Megasari, Elly; Indrayanti, Dian
KOMUNITA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 4 No 2 (2025): Mei
Publisher : PELITA NUSA TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60004/komunita.v4i2.178

Abstract

This community service program aimed to educate adolescent girls in Dusun Gembleb, Trenggalek, on the benefits of red ginger (Zingiber officinale) as a natural remedy for alleviating menstrual pain. Menstrual pain, or dysmenorrhea, is a common health issue affecting a significant number of adolescent girls, often leading to disruption in daily activities. While conventional pain relief medications are commonly used, their long-term side effects can be detrimental. Red ginger, known for its anti-inflammatory and analgesic properties, offers a safer alternative. The program, held on May 3, 2025, at the Gembleb Village Office, included educational sessions on the medicinal properties of red ginger, practical demonstrations on how to prepare red ginger tea, and discussions on its health benefits. The results showed a significant improvement in participants' understanding of red ginger's therapeutic effects, as evidenced by pre-test and post-test comparisons. This initiative successfully raised awareness about alternative treatments and empowered the community to utilize locally available resources for health improvement.
Analisis Tingkat Pengetahuan dan Perilaku Swamedikasi Obat Analgesik di Apotek Sumber Urip Jaya: Analysis of Knowledge Level and Self-Medication Behavior of Analgesic Drugs at Sumber Urip Jaya Pharmacy, Kediri Probosiwi , Neni; Ilmi , Tsamrotul; Laili, Nur Fahma; saristiana, yuneka; Sukmawati, Datin An Nisa
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 6 No. 1 (2024): Volume 6, No.1, Desember 2024
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v6i1.6487

Abstract

Swamedikasi merupakan tindakan dalam memilih dan menggunakan obat tanpa resep dokter untuk mengatasi masalah kesehatan atau gejala tertentu yang dirasakan. Tujuan penelitian ini untuk analisis tingkat pengetahuan dan perilaku swamedikasi obat analgesik di Apotek Sumber Urip Jaya. Sampel yang digunakan pada penelitian ini sebanyak 105 responden. Instrumen penelitian berupa kuesioner pengetahuan yang terdiri dari 10 pertanyaan domain kepercayaan swamedikasi, 3 pertanyaan cara mendapatkan obat, 3 pertanyaan cara menggunakan obat, 3 pertanyaan cara penyimpanan obat, dan kuesioner perilaku swamedikasi sebanyak 10 pertanyaan. Penelitian ini dilakukan pada bulan Maret – Mei dan dilakukan di Apotek Sumber Urip Jaya. Analisis data menggunakan SPSS versi 16.0 dengan menggunakan uji chisquare. Hasil penelitian menunjukkan  sebagian besar berusia 36-45 tahun, dengan pendidikan terakhir SMA  dan berprofesi sebagai wiraswasta, mayoritas responden pada indikator kepercayaan swamedikasi (91,42%), cara mendapatkan obat (85,71%), cara penyimpanan obat (86,67%). Nilai signifikansi 0,000 yang artinya terdapat hubungan yang signifikan antara tingkat pengetahuan dan perilaku swamedikasi di apotek Sumber Urip Jaya
Identification of Active Compounds from Sambung Nyawa Leaves (Gynura procumbens (Lour.) Merr) as Potential Natural Antioxidant and Anti-inflammatory Agents Saristiana, Yuneka; Salmasfattah, Novyananda; Prasetyawan, Fendy; Savitri, Lisa; Kadir, Mujtahid Bin Abd
PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS Vol. 4 No. 3 (2025): JULY
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/comorbid.v4i3.1865

Abstract

Diseases caused by oxidative stress and inflammation are global health problems that encourage the search for alternative treatments from natural materials. Grapevine leaves (Gynura procumbens (Lour.) Merr.) have long been empirically used, but scientific validation of their potential is still limited. The objective of this research is to identify and describe the active substances in sambung nyawa leaves and assess their effectiveness as natural antioxidants and anti-inflammatory agents. The study involves conducting laboratory experiments, starting with the extraction of sambung nyawa leaves using 96% ethanol solvent through a maceration process. The extract obtained is then analysed for its phytochemical composition. The antioxidant activity is evaluated using the DPPH method to determine the IC₅₀ value. On the other hand, the anti-inflammatory properties are tested in male Wistar rats following the induction of rat hind paw edema with 1% carrageenan, using extract doses of 75, 150, and 300 mg/kgBW. The findings indicate a 13.4% yield from the extraction process. The phytochemical analysis reveals the presence of flavonoids, alkaloids, saponins, tannins, phenols, and steroids/triterpenoids. The antioxidant test results show a moderate level of activity with an IC₅₀ value of 89.26 µg/mL. In the anti-inflammatory test, the 150 mg/kgBW dose demonstrates the highest efficacy with a 52.00% reduction in edema, comparable to the positive control triamcinolone (55.00%). In summary, the ethanol extract of sambung nyawa leaves exhibits promising potential as an antioxidant and anti-inflammatory agent, indicating its suitability for further development as a botanical pharmaceutical ingredient.
Assessment of Escherichia coli Contamination in Drinking Water from Refill Depots Savitri, Lisa; Kholis, Muhammad Akbar Nur; Prasetyawan, Fendy; Saristiana, Yuneka; Amanda, Cornelia; Mebung, Konradus Klala
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.443-446

Abstract

Refill Drinking Water Depots (DAMIU) have become a popular source of drinking water in Indonesia due to their affordability and accessibility. However, concerns about hygiene and microbial contamination persist, particularly in areas with limited health oversight. This study aimed to evaluate the microbiological quality of refilled drinking water in Kediri City by detecting the presence of Escherichia coli as an indicator of fecal contamination. A descriptive, cross-sectional design involving 22 depots selected based on hygiene criteria was employed. Microbiological analysis used the Most Probable Number (MPN) method, with confirmatory tests including IMViC and Eosin Methylene Blue (EMB) media. The results showed that 20 of 22 depots met the microbiological safety standard of 0 CFU/100 mL for E. coli as set by the Indonesian Ministry of Health and national standards (SNI 3554:2015). Two samples (5 and 7) tested positive for E. coli, likely due to environmental contamination, inadequate sanitation, and poor water handling practices. The positive samples demonstrated typical E. coli characteristics in IMViC (++-+) and gas formation in BGLB media. This study underscores the importance of routine surveillance, public health regulation enforcement, and improved hygiene practices in refilled water depots. Ensuring the microbiological safety of refilled drinking water is essential to prevent waterborne diseases such as diarrhea. The findings call for enhanced collaboration between local health offices and depot operators to maintain clean and safe drinking water standards across communities.
Immunomodulatory Activity of Chinese Betel (Peperomia pellucida L.) Extract on the Spleen Histopathology in a Murine Model of Gastroenteritis Savitri, Lisa; Prasetyawan, Fendy; Saristiana, Yuneka; Meri, Meri; Mebung, Konradus Klala; Amanda, Cornelia
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.447-452

Abstract

Gastroenteritis, a prevalent digestive disorder caused by various pathogens including Escherichia coli, remains a global health challenge with significant morbidity and mortality, particularly in low-income countries. The spleen, as a critical immune organ, is often compromised during systemic infections. Peperomia pellucida (L.) , a traditional medicinal herb, is known for its antimicrobial, anti-inflammatory, and antioxidant properties. This study investigates the histopathological effects of P. pellucida leaf ethanol extract on spleen tissue in mice induced with E. coli to model bacterial gastroenteritis. Thirty male Swiss mice were divided into six groups (n=5): normal control, negative control (aquades), positive control (Yakult), and three treatment groups receiving P. pellucida extract at 100, 300, and 500 mg/kg BW. After seven days of pretreatment, mice were orally infected with E. coli (1×10⁶ CFU/mL) for another seven days. Spleen tissues were harvested, fixed, and stained with hematoxylin-eosin for histopathological evaluation focusing on degeneration, necrosis, and PMN infiltration. Statistical analysis was performed using ANOVA followed by LSD tests. The highest dose of P. pellucida extract (500 mg/kg BW) significantly reduced spleen tissue damage, showing decreased degeneration (9.08%), necrosis (6.05%), and PMN infiltration (18.45%) compared to lower doses. The effect was comparable to the positive control. The ethanol extract of P. pellucida demonstrates a dose-dependent protective effect on spleen histopathology in E. coli-induced gastroenteritis in mice, supporting its potential as a natural antiseptic agent.
Co-Authors Abd Rofiq Achmad Wahdi Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Akhmal, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arsiaty Sumule Ary Kristijono Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Ema Jayanti Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Charliandri Saputra Wahab Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Edda, Ilda Rambu Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo, Elfred Rinaldo Elsa Mahardika Putri Elsa Mahardika Putri Ema Tri Wulan Emma Jayanti Besan Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hakim, Adiyansyah Lukman Hasriyani Hasriyani Hasriyani, Hasriyani Herman Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Imran, Arlan K Indrayanti, Dian Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kholis, Muhammad Akbar Nur Kristjono, Ary Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lusiana Aprillia M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Okky Intan Mawarni Oktadiana, Isma Prasetyo Nugroho, Bandhi Prayoga Fery Yuniarto Probosiwi , Neni Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda savitri, Lisa Shinta Mayasari Shinta Mayasari Sugeng Santoso Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Zahra, Ilhawa