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All Journal International Journal of Public Health Science (IJPHS) Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Farmasi Klinik Indonesia Pharmacon Majalah Obat Tradisional Public Health of Indonesia Biomedical Journal of Indonesia Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Pharmasipha JFL : Jurnal Farmasi Lampung Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Insan Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Sciences of Pharmacy Jurnal Kesehatan Bakti Tunas Husada Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia
Lalu Muhammad Irham
Faculty Of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Sciences of Pharmacy

 1 
Formulation and Stability Evaluation of Red Dragon Fruit (Hylocereus polyrhizus) Extract Gel Febrianti, Novi; Widyastuti, Lina; Saputri, Septiana; Irham, Lalu Muhammad
Sciences of Pharmacy Volume 4 Issue 4
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0404379

Abstract

Red dragon fruit (Hylocereus polyrhizus) is known for its strong antioxidant properties and potential anti-aging effects. To enhance its benefits and improve usability, this fruit extract was formulated into a gel preparation. This study aimed to determine the optimal proportions of Carbopol 940 and triethanolamine (TEA) to obtain a gel with desirable physical characteristics. The flesh of red dragon fruit was juiced and concentrated to produce an 8% extract. Three formulations were prepared with varying ratios of Carbopol 940 to TEA: 0.5%:0.3% (F1), 1.2%:0.7% (F2), and 2%:1.2% (F3). The gels were evaluated for physical properties, antioxidant activity, and antibacterial activity. The most promising formula was subjected to stability testing for three cycles under different temperature conditions: cold (3°C), room temperature (27°C), and climatic chamber (40°C, 75% RH). Results showed that formula F2 exhibited a characteristic red color, clear appearance, distinctive oleum rosae aroma, moderately thick and homogeneous consistency, viscosity of 3112.47 ± 177.90 cps, spreading diameter of 5.20 ± 0.20 cm, adhesion time of 18.45 ± 0.89 s, and pH of 5.33 ± 0.02. No significant changes were observed after the stability testing (p > 0.05), indicating that the formulation remained stable under all temperature conditions. F2 also showed higher antioxidant activity than F1 and better antibacterial properties than F3. Its stability and bioactivity support its potential as a promising natural cosmeceutical formulation.
Co-Authors Abdi Wira Septama Abdi Wira Septama Abdi Wira Septama Abdi Wira Septama Abdi Wira Septama Abdi Wira Septama Adi Wira Septama Adnan Adnan Afief, Arief Rahman Ageng Brahmadhi Akrom, Akrom Ana Hidayati Anisa Devi Kharisma Wibowo Anisa Nova Puspitaningrum Anisa Nova Puspitaningrum Anisa Nova Puspitaningrum Anita Silas La’ah Any Guntarti Arief Rahman Afief Arief Rahman Afief Arief Rahman Afief Auren Nathania Ayu Lifia Nur Kartikasari Azzahra, Fara Barkah Djaka Purwanto Barkah Djaka Purwanto Bramadi Arya Cheung, Rocky Chita Widia Chong, Rockie Citra Ariani Edityaningrum, Citra Danang Prasetyaning Amukti Darmawi . Darmawi Darmawi Daud, Intan Delfi Iskardyani Denys Chichi Kusumastuti Didik Setiawan Donel S Dyah Aryani Perwitasari Eko Mugiyanto Faridah, Imaniar Febriana Astuti Firdayani Firdayani Firdayani Firdayani, Firdayani Firman Firman Fitri, Dwiki Fredrick Dermawan Purba Galuh, Tiwi Gina Noor Djalilah Gustinanda, Rizky Haafizah Dania Haafizah Dania Haafizah Dania Handayani, Eka Wuri Hanisari, Putri Henry Budiawan Prasetya Herjanti Ratnawiningsih Herlina, Tetie Ichsan Luqmana Indra Putra, Ichsan Luqmana Indra Ilham Alifiar Ilham alifiar Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Iwan Santoso, Iwan Kartikasari, Ayu Lifia Nur Khair, Riat Khairi, Sabiah Khairurrizki, Amanda La Malihi Laela Hayu Nurani La’ah, Anita Silas Leina Putri Zahra Lisza Niarisessa Made Ary Sarasmita Maliza, Rita MARIA BINTANG Maulida Mazaya Ma’ruf, Muhammad Medi Sushanti, Nining Melodia Rezadhini Melodia Rezadhini Menit Ardhiani Menit Ardhiani Muh. Deni Kurniawan Muhammad Fathurrahman Muhammad Yusron Maulana El-Yunusi Mutmainnah Siradjuddin Nanik Sulistyani Nathania, Auren Ni Made Ary Sarasmita Nining Medi Sushanti Nining Medi Sushanti Nining Sugihartini Novi Febrianti Nugraha, Media Fitri Isma Isma Nur Ismiyati Nur Rahayuningsih Pendicho Eko Yuliyanto Pradika, Jaka Pranata, Satria Pratama, Kharisma Puriyanto, Riky Dwi Purwanto, Barkah Djaka Puspitaningrum, Anisa Nova Rafiastiana Capritasari Rahmat Dani Satria Razali, Renardy Reza Renardy Reza Razali Rezadhini, Melodia Ria Indah Pratami Riat El Khair Riat Khair Rizka Novia Atmadani Rockie Chong Rocky Cheung Rocky Cheung Rocky Cheung Rudi, Nyoman S, Donel S, Yuni Salamah, Siti Hajar Sany Sapto Yuliani Saputri, Septiana Satria, Rahmat Dani Sianu, Rahman Simanjuntak, LB Siswandi Siswandi, Siswandi Siswanto, Lalu Muhammad Harmain Siti Rofida Siti Urbayatun Solikhah Solikhah, EfA Wakhidatus Sugiyanto - Suhandri, Wiwin Suhendra, Gugun Sulistiyani, Nanik Susan Fitria Candradewi Triantoro Safaria Triantoro Safaria Uswatun Chasanah Wahyu Rahmatulloh Wahyu Widyaningsih Wahyu Widyaningsih Wibowo, Anisa Devi Karisma Wibowo, Anisa Devi Kharisma Widyastuti, Lina Wigka Pawestri, Novianti Winarto Winarto Winarto Winarto Wirawan Adikusuma Wiwin Suhandri Wiwit Ade Fidiawati Wiwit Ade Fidiawati Woro Supadmi Woro Supadmi Wulandari, D Yudha Rizky Nuari Zahra, Leina Putri Zainul Amiruddin Zakaria Zakaria, Zainul Amiruddin Zukhruf Saputri, Ginanjar