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Journal : International Journal Of Science, Technology

Phytochemical Screening And Antibacterial Activity Test Of Ethanol Extract Of Jengkol Leaves (Archidendron Pauciflorum Benth.) I.C. Nielsen Against Staphylococcus Epidermidis And Propionibacterium Acnes Munandar Nasution, Haris; Yuniarti, Rafita; Rani, Zulmai; Nursyafira, Arini
International Journal of Science, Technology & Management Vol. 3 No. 3 (2022): May 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i3.509

Abstract

Skin disease was a disease that attacked the surface of the body, and was caused by various agents, one was bacteria. One of the plants that had antibacterial activity was jengkol leaf (Archidendron pauciflorum Benth.) I.C. Nielsen because it contained compounds that had antibacterial properties that had previously been studied by other researchers against Staphylococcus aureus and Escherichia coli bacteria. So that researcher was interested in researching on the antibacterial activity of jengkol leaves (Archidendron pauciflorum Benth.) I.C. Nielsen against Staphylococcus epidermidis and Propionibacterium acnes. Fresh Jengkol leaves were processed into simplicia and extracted using 96% ethanol. Phytochemical screening was carried out on simplicia powder and extracts of jengkol leaves. Ethanol extract jengkol leaves was made in several concentrations, namely 20%, 25%, and 30%, positive control using Tetracycline HCl, and negative control using 1% DMSO. There were several tests carried out on jengkol leaves in addition to phytochemical screening, namely examination of simplicia characteristic including macroscopic examination, microscopic examination, examination of water content, examination of water-soluble extract levels, examination of ethanol-soluble extracts, examination of total ash content, and also an examination of acid-insoluble ash levels and antibacterial activity test of jengkol leaves. The results of phytochemical screening showed that the compound of jengkol leaves (Archidendron pauciflorum Benth.) I.C. Nielsen contained a class of secondary metabolites of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. And for the results of the antibacterial activity research also showed that jengkol leaves could be used as antibacterial because it has a strong inhibitory power at a concentration of 20% and the strongest at a concentration of 30% against Staphylococcus epidermidis, namely 15.06 mm and 17.83 mm, while in diameter of growth inhibition zone Propionibacterium acnes was 15.86 mm and 18.1 mm.
The Buas Buas Leaf Utilization of Buas Buas Leaf (Premna pubescens Blume) Ethanol Extract as Liquid Soap With Anti-Bacteria Activity Rafita, Rafita Yuniarti; Munandar Nasution, Haris; Rani, Zulmai; Fahmi, Fahmi
International Journal of Science, Technology & Management Vol. 3 No. 3 (2022): May 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i3.510

Abstract

The buas buas (Premna pubescens Blume) plant is from the Lamiaceae family. The use of ethanol extract of buas buas leaf (Premna pubescens Blume) as soap is because soap is one of the health products needed by many people to maintain a healthy body. It is used as an antibacterial because buas buas leaves contain secondary metabolites that can be used as antibacterial.The Buas buas leaf Simplicia (Premna pubescens Blume) was extracted using 96% ethanol by maceration and concentrated with a rotary evaporator to evaporate the solvent. The concentrated extract obtained was tested by phytochemical screening, formulated into liquid soap with concentrations of 5%, 10%, 15% and tested for pH, foam height, viscosity, specific gravity and irritation test, and antibacterial activity against staphylococcus aureus bacteria. The results of the phytochemical screening test of the ethanol extract of buas buas leaf (Premna pubescens Blume) contained secondary metabolites in the form of alkaloids, flavonoids, saponins, tannins and steroids/triterpenoids. Liquid soap made with concentrations of 5%, 10%, and 15% has a pH of 10-10.3; foam height 50-90 mm; viscosity 1210-1290 cP; specific gravity 1-1.08 and did not cause irritation to volunteers; and have inhibitory power of 14.2 mm, 15.0 mm, 16.0 mm, and 20.0 mm against Staphylococcus aureus bacteria, respectively.
Co-Authors A'dilah, Nur Adela Octi Dwiyani Adelia Ramadani Adjelie, Tiara Afifah, Puan Ibni Afriati, Nelsi Afrida Yeti Aliza, Ulfa Andjelie, Tiara Anggraini, Dea Puspa Ani Sutiani Anny Sartika Daulay Ariandi Arianti, Sellin Arina Asmarani, Asmarani Aula, Rizki Pebri Aulia Fitri, Aulia Aulia, Meisyah Awanis, Safirah Bilal, Mohd. Chairina Milda Cindy Marlina Tambunan Cut Erika Maulydya D. Elysa Putri Mambang D. Elysa Putri Mambang Dama Yanti, Fradilla Daniel Happy Putra Debi Meilani Dewa, Fasca Dewi Firmayani Dewi, Sri Harti Dikki Miswanda Dina Veranika Dinda Sari Utami Eva Fransiska Fahmi Fahmi Farida Yani Fauziah Zain Fithri Pulungan, Ainil Fitri Febriani Fitri, Raissa Gabena Indrayani Dalimunthe Haris Munandar Nasution Hendraputra, Hardy Handoko Heru Adha Prayogo Humaira, Yara Hutagalung, Riris Br Hutagalung, Victor H Ika Fitriani Indah Nasution Indri Juliarni Inna Myesha Jurida, Wike Juwita, Sukma Karismawati Karlina Butar Butar Khairina Khairunnisa , Ardina Kiki Rawitri Linda, Rosa Lisda Mayanti Lubis, Minda Sari Lubis, Nurazizah Lubis, Zulkifli Ismail Luthfianida, Arifna M Pandapotan Nasution M. Naufal Rifqi M. Pandapotan Nasution Maharani, Suci Mambang, D Elysa Putri Maulana Putri, Yasinta Mayani, Nurhikma Maysarah, Aulya Metami Sihombing, Juliana Meylisa Pratami Br Sinaga Milwani Harahap Minda Sar Lubis Miranza, Nona Misna Rosalinda Hutabarat Muhammad Amin Nasution Muhammad Ari Mukhtizar Muhammad Pandapotan Nasution Muhammad Tegar Tri Rizky Muslim, Nur’Aini Jumah Nasri Nasri, Nasri Nasution, M. Pandapotan Natasya, Siti Adinda Nia Novranda Pertiwi Novi Yuliandari Novia Sari Novita Sari, Helsa Nur Asia, Nur Nur, Hijrotun Nuratika, Eli Nurfadilla, Kiki Nurliansyah, Nurliansyah Nursyafira, Arini Oktavia, Zela Pasaribu, Mesi Wilia Afrima Pasaribu, Mesi Willia Afrima Peri , Peri Peri, Peri Pertiwi, Rahma Purba, Juvantri Fablo Puteri, Cut Intan Annisa Putri Theresia Harianja Putri, Nadya Iwani Rahma Maulidia Fitri Rambe, Sitiapsah Reza Irma Riani, Nur Aslin Ricky Andi Syahputra Ridwan Taher Lubis Ridwanto Ridwanto Ridwanto Rifqi, M. Ainur Risma Fauziah Pasaribu Ritonga , Septi Ani Ritonga, Oktavia Rukmana, Siti Sagita Marina Simatupang Samosir, Anzly Hasian Saragih, Aqilah Mutmainnah Sari Lubis, Winda Sari, Syilvi Rinda Sartika Daulay, Anny Shinta Mida Ariani Harahap Siagian , Anggi Yani Sihotang, Laura Indah Restu silalahi, zahra salsabila Sindy Putri Utami Siregar , Runisya Maugin Utami Siregar, Hikmatussabaria Siregar, Rina Paramitha Siti Anisa Sri Harti Sri Mulia Ningsih Siregar Sri Murni Sri Natalia Saragih Sri Ria Ranti Sri Wahyuni Sulwiyatul K Sani Sunita, Della Syafa Nadira Ashiilah Syafirna, Nada Syahputra, Ricky Andi Syarifah Aulia Tasya Ardana Tia Nazilla Tri Damaiyanti Ummi Khairani Rambe Ummu Safura Sirait Vera Estefania Kaban Wahdaniati , Tri Wijiyaningsih, Dinda Wilda Septia Winda Aulia Yayuk Putri Rahayu Yayuk Putri Rahayu Yuni Sartika Zahara, Fitria Siti Zannah , Muhamad Zhafirah, Rana Ziza Putri Aisyia Fauzi Zulhij, Fizrya Zulmai Rani