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All Journal JURNAL PENELITIAN SAINTIKA Acta Pharmaceutica Indonesia AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Ilmiah Manusia dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Indonesian Journal of Pharmaceutical and Clinical Research Jurnal Aisyah : Jurnal Ilmu Kesehatan International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Chemical Science and Technology Jurnal Kesehatan Tambusai Jurnal Buana Farma JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal EduHealth Bulletin of Community Engagement Jurnal Farmanesia PEMA: Jurnal Pendidikan dan Pengabdian Kepada Masyarakat Journal of Health and Medical Science International Journal of Health and Pharmaceutical (IJHP) Sciences of Pharmacy FARMASAINKES PCJN Pharmaceutical and Clinical Journal of Nusantara Usada Nusantara: Jurnal Kesehatan Tradisional Journal of Pharmaceutical and Sciences. JK Jurnal Kesehatan Scientica: Jurnal Ilmiah Sains dan Teknologi Medic Nutricia : Jurnal Ilmu Kesehatan Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara Jurnal Sains dan Kesehatan
Yuniarti, Rafita
Universitas Muslim Nusantara Al-Washliyah
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Journal : Jurnal EduHealth

 1 
The Antibacterial Activity Of Conventional Serum And Nano Face Serum From Pineapple Stem Extract (Ananas Comosus (L.) Merr) Against Staphylococcus Epidermidis Minda Sar Lubis; Asmarani, Asmarani; Rafita Yuniarti; Haris Munandar Nasution
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Pineapple hump has been identified to contain secondary metabolites in saponin, flavonoid, and steroid/triterpenoid which show potential as antibacterial agents against Staphylococcus epidermidis. These bacteria are part of the normal composition of gram-positive bacteria on human skin and do not display any pathogenic characteristics. Even so, these bacteria can trigger facial skin infections, especially in the form of pimples which are often difficult to treat. This study aimed to determine the differences in bacterial inhibition of cosmetic preparations in the form of conventional serum and nano serum from pineapple hump extract (Ananas comosus (L.) Merr) against bacteria Staphylococcus epidermidis. This research uses the method of True Experimental. In this study, pineapple hump was extracted and formulated into conventional serum preparations and nano serum with various concentrations, then tested for its antibacterial activity against the bacteria Staphylococcus epidermidis. Diameter of antibacterial inhibition of conventional Serum Pineapple hump Extract against bacteria Staphylococcus epidermidis i.e., Blank has no inhibition, 2% concentration (10.10 mm), 10% concentration (11.28 mm) and 20% concentration (13.26 mm). The diameter of inhibition of Nano serum Pineapple Hump Extract, namely Blank, had no inhibition, 2% concentration (10.44 mm), 10% concentration (11.56 mm) and 20% concentration (15.14 mm). The positive control for Clindamycin had an inhibitory effect (32.8 mm), the positive control for the circulating Pineapple Hump Extract (15.52 mm) and the negative control had no inhibition.
The Antibacterial Activity Test Of Leaf Extract Nanoparticles Of Senggani (Melastoma Candidum D.Don) Against Cutibacterium Acnes And Staphylococcus Epidermidis Bacteria Tia Nazilla; Muhammad Amin Nasution; Minda Sari Lubis; Rafita Yuniarti
Jurnal EduHealth Vol. 15 No. 04 (2024): Jurnal EduHealt (inpres), Year 2024
Publisher : Sean Institute

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The aim of this research is to explore and delve deeper into the reasons families request passive euthanasia, the illnesses and conditions that lead individuals to consider such actions, and how the principle of patient autonomy is applied in euthanasia practices at KH. Daud Arif Regional General Hospital, Kuala Tungkal. The research employs a qualitative approach through literature review studies. Data were collected from journals, books, and previous studies, focusing on the withdrawal of life-support measures and the ethical principle of autonomy. The collected information was analyzed to support the research. Based on the findings, decisions regarding euthanasia, particularly passive euthanasia, should ideally be made by patients when they are mentally capable. However, in critical conditions where the patient is incapacitated, the responsibility is transferred to the patient's family, who can make decisions on their behalf, including opting for passive euthanasia. While active euthanasia remains illegal in Indonesia, passive euthanasia, such as the cessation of life-support interventions, is permitted under certain legal frameworks, such as Ministry of Health Regulation No. 37 of 2014. This regulation also emphasizes the importance of therapeutic contracts between patients and healthcare providers. The reasons families or patients choose passive euthanasia at KH. Daud Arif Regional General Hospital, Kuala Tungkal, include prolonged physical suffering and a significant decline in quality of life. The illnesses or conditions considered for passive euthanasia include chronic, incurable diseases that cause ongoing suffering, such as heart disease, kidney failure, or illnesses with poor prognoses.
Formulation And Evaluation Of Anti-Aging Face Spray Preparation With Ethanol Extract Of Shoe Flower (Hibiscus Rosa-Sinensis L.) And DPPH Method Antioxidant Activity Test Syafa Nadira Ashiilah; Rafita Yuniarti; Minda Sari Lubis; Zulmai Rani
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

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Beauty is one of the aspects pursued by women, particularly in terms of skin care. Among the skincare products commonly used by Indonesians is face spray, which offers various benefits, such as protecting against free radicals from ultraviolet rays, preventing premature aging, and addressing dry skin. Antioxidant effects are more effective when formulated in topical preparations, such as cosmetics, compared to oral administration. Hibiscus flower is a plant that contains flavonoids, which function as antioxidants capable of protecting the skin from free radical damage, moisturizing, and enhancing skin circulation. This research is experimental in nature. In this study, ethanol extract face sprays from hibiscus flowers were prepared with concentrations of 0.1%, 0.3%, 0.5%, and 0.7%. The face sprays underwent evaluations for physical quality, preference tests, irritation tests, antioxidant activity tests, and anti-aging effectiveness tests. The anti-aging effectiveness data were analyzed using SPSS with a parametric ANOVA test. Based on the physical quality evaluation, the best formulation was the face spray with a 0.5% extract concentration. It exhibited stable organoleptic characteristics, a pH within the skin’s range of 5–7.26, good spreadability, no coarse particles or clumps, and stability during a 28-day stability test at room temperature (25°C) and a cycling test over 6 cycles. Moreover, it did not irritate the skin. The antioxidant activity test revealed that face sprays with 0.1% and 0.3% extract concentrations showed moderate antioxidant activity, while those with 0.5% and 0.7% concentrations demonstrated strong antioxidant activity. In the anti-aging effectiveness test, all formulations exhibited anti-aging effects.
Formulation And Evaluation Of Anti-Aging Face Spray Preparation From Ethanol Extract Of Rosemary Leaf (Salvia Rosmarinus Spenn.) And Antioxidant Activity Test Using The DPPH Method Inna Myesha; Rafita Yuniarti; Minda Sari Lubis; Zulmai Rani
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

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Abstract

The skin's need to prevent premature aging requires skincare products with antioxidant content. A popular skincare product used today is face spray. Face sprays containing active ingredients as antioxidants are beneficial in preventing premature aging. One of the plants known for its antioxidant properties is rosemary leaf (Salvia rosmarinus Spenn.). The development of face spray with the addition of rosemary leaf extract is a form of utilizing plants in cosmetic products. This study is an experimental research. In this study, rosemary leaf ethanol extract face spray was formulated with concentrations of 0%, 0.5%, 1%, 3%, and 5%. Evaluation included physical quality, hedonic test, irritation test, antioxidant activity test, and anti-aging effectiveness test. Anti-aging data were analyzed using SPSS. Based on physical quality evaluation, the face spray formula with the best physical quality was found at extract concentrations of 1%, 3%, and 5%, with observations indicating stable organoleptic properties, pH within the skin range of 4.5-6.5, good spreading ability, no coarse particles or clumping, and stable formulations after 28 days of room temperature stability testing (25°C) and 6 cycle cycling tests. The formulations also showed no irritation to the skin. In the antioxidant activity test, the 0.5% extract concentration exhibited moderate antioxidant activity, while concentrations of 1%, 3%, and 5% showed strong antioxidant activity. In the anti-aging effectiveness test using a skin analyzer, each formula demonstrated significant differences in skin changes with a p-value of <0.05.
Co-Authors A'dilah, Nur Adela Octi Dwiyani Adelia Ramadani Adjelie, Tiara Afifah, Puan Ibni Afriati, Nelsi Afrida Yeti Aliza, Ulfa Andjelie, Tiara Anggraini, Dea Puspa Ani Sutiani Anny Sartika Daulay Ariandi Arianti, Sellin Arina Asmarani, Asmarani Aula, Rizki Pebri Aulia Fitri, Aulia Aulia, Meisyah Awanis, Safirah Bilal, Mohd. Chairina Milda Cindy Marlina Tambunan Cut Erika Maulydya D. Elysa Putri Mambang D. Elysa Putri Mambang Dama Yanti, Fradilla Daniel Happy Putra Debi Meilani Dewa, Fasca Dewi Firmayani Dewi, Sri Harti Dikki Miswanda Dina Veranika Dinda Sari Utami Fahmi Fahmi Farida Yani Fauziah Zain Fithri Pulungan, Ainil Fitri Febriani Fitri, Raissa FRANSISKA, EVA Gabena Indrayani Dalimunthe Haris Munandar Nasution Hendraputra, Hardy Handoko Heru Adha Prayogo Humaira, Yara Hutagalung, Riris Br Hutagalung, Victor H Ika Fitriani Indah Nasution Indri Juliarni Inna Myesha Jurida, Wike Juwita, Sukma Karismawati Karlina Butar Butar Khairina Khairunnisa , Ardina Kiki Rawitri Linda, Rosa Lisda Mayanti Lubis, Minda Sari Lubis, Nurazizah Lubis, Zulkifli Ismail Luthfianida, Arifna M Pandapotan Nasution M. Naufal Rifqi M. Pandapotan Nasution Maharani, Suci Mambang, D Elysa Putri Maulana Putri, Yasinta Mayani, Nurhikma Maysarah, Aulya Metami Sihombing, Juliana Meylisa Pratami Br Sinaga Milwani Harahap Minda Sar Lubis Miranza, Nona Misna Rosalinda Hutabarat Muhammad Amin Nasution Muhammad Ari Mukhtizar Muhammad Pandapotan Nasution Muhammad Tegar Tri Rizky Muslim, Nur’Aini Jumah Nasri Nasri, Nasri Nasution, M. Pandapotan Natasya, Siti Adinda Nia Novranda Pertiwi Novi Yuliandari Novia Sari Novita Sari, Helsa Nur Asia, Nur Nur, Hijrotun Nuratika, Eli Nurfadilla, Kiki Nurliansyah, Nurliansyah Nursyafira, Arini Oktavia, Zela Pasaribu, Mesi Wilia Afrima Pasaribu, Mesi Willia Afrima Peri , Peri Peri, Peri Pertiwi, Rahma Purba, Juvantri Fablo Puspita, Dinda Dila Puteri, Cut Intan Annisa Putri Theresia Harianja Putri, Nadya Iwani Rahma Maulidia Fitri Rambe, Sitiapsah Reza Irma Riani, Nur Aslin Ricky Andi Syahputra Ridwan Taher Lubis Ridwanto Ridwanto Ridwanto Rifqi, M. Ainur Risma Fauziah Pasaribu Ritonga , Septi Ani Ritonga, Oktavia Rukmana, Siti Sagita Marina Simatupang Samosir, Anzly Hasian Saragih, Aqilah Mutmainnah Sari Lubis, Winda Sari, Syilvi Rinda Sartika Daulay, Anny Shinta Mida Ariani Harahap Siagian , Anggi Yani Sihotang, Laura Indah Restu silalahi, zahra salsabila Sindy Putri Utami Siregar , Runisya Maugin Utami Siregar, Hikmatussabaria Siregar, Rina Paramitha Siti Anisa Sri Harti Sri Mulia Ningsih Siregar Sri Murni Sri Natalia Saragih Sri Ria Ranti Sri Wahyuni Sulwiyatul K Sani Sunita, Della Syafa Nadira Ashiilah Syafirna, Nada Syahputra, Ricky Andi Syarifah Aulia Tasya Ardana Tia Nazilla Tri Damaiyanti Ummi Khairani Rambe Ummu Safura Sirait Vera Estefania Kaban Wahdaniati , Tri Wijiyaningsih, Dinda Wilda Septia Winda Aulia Yayuk Putri Rahayu Yayuk Putri Rahayu Yuni Sartika Zahara, Fitria Siti Zannah , Muhamad Zhafirah, Rana Ziza Putri Aisyia Fauzi Zulhij, Fizrya Zulmai Rani