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All Journal Hemera Zoa Media Veteriner Jurnal Ilmu dan Kesehatan Hewan Buletin Veteriner Udayana Majalah Ilmiah Peternakan Jurnal Veteriner Indonesia Medicus Veterinus Ecotrophic, Journal of Environmental Science Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Media Kedokteran Hewan Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis Journal of Veterinary and Animal Sciences Jurnal Medika Veterinaria

I Ketut Berata

Fakultas Kedokteran Hewan Universitas Udayana Bali

Author-ID : 242021

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Efek Ekstrak Daun Ashitaba (Angelica keiskei) Terhadap Gambaran Histopatologi Ginjal Mencit (Mus musculus) Jantan Made Oka Adinata; I Wayan Sudira; I Ketut Berata
Buletin Veteriner Udayana Vol. 4 No.2 Agustus 2012
Publisher : The Faculty of Veterinary Medicine, Udayana University

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Penelitian ini bertujuan untuk mengetahui efek ekstrak etanol daun Ashitaba (Angelicakeiskei) yang diberikan secara oral dengan dosis bervariasi terhadap gambaran histopatologiginjal mencit. Sampel yang digunakan dalam penelitian ini berjumlah 25 ekor mencit(Musmusculus) jantan dengan rata-rata berat badan 25-30 gram dan dibagi menjadi limagrup perlakuan. Perlakuan pertama tidak diberikan ekstrak etanol daun Ashitaba atausebagai kontrol. Perlakuan kedua sampai keempat masing-masing diberikan dosis 125mg/kg berat badan (bb); 250 mg/kg bb; 500 mg/kg bb; dan 1.000 mg/kg bb. Perlakuandiberikan secara oral setiap hari dalam waktu 21 hari. Pada hari ke 22, semua mencitdinekropsi dan ginjal diambil untuk selanjutnya dibuat preparat histopatologi denganpewarnaan hematoksilin eosin (HE). Perubahan histopatologi diperiksa berdasarkan adanyadegenerasi melemak, peradangan dan nekrosis. Hasil dari pemberian ekstrak etanol daunAshitaba (Angelica keiskei) dengan dosis 125 mg/kg bb, dua ekor mencit mengalamidegenerasi melemak dan infiltrasi sel radang dan satu mencit mengalami nekrosis.Pemberian dosis 250 mg/kg bb, tiga ekor mencit mengalami degenerasi melemak daninfiltrasi sel radang dan satu ekor mencit mengalami nekrosis. Pemberian dosis 500 mg/kgbb, tiga ekor mencit mengalami degenerasi melemak dan infiltrasi sel radang dan satu ekormencit mengalami nekrosis. Pemberian dosis 1000 mg/kg bb, tampak adanya infiltrasi selselradang, degenerasi melemak dan nekrosis pada semua mencit yang digunakan.Simpulan penelitian adalah pemberian ekstrak etanol daun Ashitaba pada dosis 1000 mg/kgbb dapat menimbulkan gangguan gambaran struktur histopatologi ginjal mencit (Musmusculus) jantan.

Ekstrak Etanol Sarang Semut Menyebabkan Kerusakan Struktur Histologi Ginjal Mencit Dini Hilary Manullang; I Wayan Sudira; I Ketut Berata; I Made Merdana
Buletin Veteriner Udayana Vol. 10 No. 2 Agustus 2018
Publisher : The Faculty of Veterinary Medicine, Udayana University

Chemical analysis of the ant-plant (Myrmecodia pendans) showed that plants have various chemical compounds of flavonoids, tannins, tocopherols, multimineral and polysaccharides. The aim of this study was to find out the effect of ethanolic extract of ant-plant on histopathological changes in male mice (Mus musculus) kidney. Twenty four clinically healthy mice at aged 10-12 with weight 25 to 35 g were obtained for this study. The sample were divided into four groups randomly, each treatment group consisted of six mice. Group P0 is the negative control group were given standard feed and drink, P1 is a group were given standard feed and ethanol extracts ant plant with a dose of 100 mg/kg body weight, P2 is a group were given standard feed and ethanol extracts ant plant with a dose of 200 mg/kg of body weight, P3 is a group were given standard feed and ethanol extracts ant plant with a dose of 300 mg/kg. After completion of the treatment on the day, the kidney was taken for histological preparations were made and stained with the hematoxylin-eosin method. The variables examined were haemorrhage, degeneration and necrosis in the renal proximal tubules. The Kruskal-Wallis test results showed that ethanol extract of ant-plant had a significant effect (P?0.05) on the incidence of hemorrhage in the renal tubules. Based on these results it can be concluded that the ethanol extract of ant-plant with a dose of 300 mg/kg body weight can cause kidney histopathological changes such as hemorrhage, degeneration, and necrosis.

Pengaruh Pemberian Vitamin E dan Deksametason Terhadap Gambaran Histopatologi Jantung Tikus Putih Jantan Ayu Prawitasari Citra Pratama; I Ketut Berata; Samsuri Samsuri; I Made Merdana
Buletin Veteriner Udayana Vol. 10 No. 2 Agustus 2018
Publisher : The Faculty of Veterinary Medicine, Udayana University

Dexamethasone is a widely used synthetic glucocorticoid by people. However, the use of high doses of the long term can affect the heart. The heart is the place where drugs and other toxic substances are metabolized. However, specific studies in examining the effect of dexamethasone on heart’s histopathology are rare. Vitamin E is a fat-soluble vitamin that acts as an antioxidant which can help the body to eliminate oxidative stress in cells. The aim of this study is to know the effect of vitamin E in rat’s (Rattus norvegicus) heart given dexamethasone. This study used 25 male rats (Rattus norvegicus), which were two-three months old and 200-300 g of weight. Rats were grouped into five treatment groups and five repeats. Rats adapted for a week, and furthermore, rats were given treatments for 14 days. In the P0 treatment group rats given only food and drink (negative control). Treatment group P1, P2, P3, and P4 were given dexamethasone 0.13 mg/kg by subcutaneous injection. Vitamin E administrated orally with the following doses: P2 (100 mg/kg), P3 (150 mg/kg), and P4 (200 mg/kg). After 14 days, then the rats were necropsied to collect the heart. Next, the heart was put into Neutral Buffered Formalin (NBF) for fixation, then stained with hematoxylin-eosin staining (HE). The observed parameters were inflammation and necrosis of the heart. The result showed administration of 200 mg/kg of vitamin E had highly significant (P<0.01) to repair of rats’ heart tissue which were given 0.13 mg/kg of dexamethasone via subcutaneous injection rather than 200 mg/kg of vitamin E. The conclusions of this study are vitamin E can against heart damage due to side effects of dexamethasone.

Gambaran Histopatologi Selaput Lendir Kantung Empedu Sapi Bali yang Terinfeksi Cacing Fasciola gigantica (HISTOPATOLOGICAL ILLUSTRATION OF GALL BLADDER MUCOUS MEMBRANE INFASCIOLA GIGANTICA INFECTED BALI CATTLE) I Made Kardena; Ida Bagus Oka Winaya; Elyda .; I Dewa Made Adhiwitana; AAA Mirah Adi; I Ketut Berata
Jurnal Veteriner Vol 17 No 1 (2016)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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This study aims were to describe lesions and their intensities of histopathological changes in gallbladder mucosa of bali cattle that infected with Fasciola gigantica. As many as 42 gall bladers of balicattle were used in this studi, i.e: 35 samples were infected and sefen were non-infected with F.gigantica.The samples were randomly gathered from Pesanggaran slaughter house in Denpasar. The gall bladderswere evaluated macroscopically and prepared for microscopically examination using haematoxylin andeosin staining.The result showed that there were histopathological changes observed in the mucosa of thegall bladder:necrosis cells of gall bladder with intencity 100%, hemorrhage 68.5%, hyperplasia serousgland and mucous hypertrophy gland 100%, collagen in filtration 100%, fibroblast proliferation 91.4%,and infiltration of inflammation cells, 74.2%. Histopathological changes in gallbladders mucous of balicattle infected F.gigantica experiencing severe lesons with frequency percentage above 50%.

Pengaruh Pemberian Ekstrak Akar Alang-Alang terhadap Hati Mencit yang Menderita Gangguan Patologi (THE INFLUENCE OF THE ROOT OF SEDGE GRASS EXTRACTION ON LIVER OF MICES THAT TO SUFFER A PATHOLOGICAL DAMAGED) I Ketut Berata; Ida Bagus Oka Winaya
Jurnal Veteriner Vol 4 No 1 (2003)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Peningkatan Limfosit, Monosit, dan Basofil pada Sapi Bali yang Digembalakan di Tempat Pembuangan Akhir Sampah Kota Denpasar (THE ELEVATION LEVEL OF LIMPHOCYTE, MONOCYTE, AND BASOPHIL ON BALI CATTLE GRAZING AT WASTE DISPOSAL CITY OF DENPASAR) I Nyoman Tirta Ariana; Anak Agung Oka; I Gede Suranjaya; I Ketut Berata
Jurnal Veteriner Vol 19 No 1 (2018)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

The Bali cattles that grazing at Denpasar city waste disposal need to examined for their healthy to keep the quality of beef production. The aim of this research to determine the hematologic profile of Bali cattle was grazing at waste disposel in Denpasar. The data obtained is expected to provide an initial ekspretion of the general health-related to productivity. Studies using nine female of Bali cattle weighing 250-300 kg, aged 2-3 years. Research using quantitative methods by means of surveys and research laboratory. The research variables are Total White blood cells (WBC), lymphocytes, monocytes, basophils, and Total Red blood cell (RBC), haemoglobin (Hb), mean corpuscular volume (MCV). The result showed that the total of RBC, Hb, and MCV were still within the normal range. The other result were the average WBC: 4.8%, lymphocytes: 25.3%, Monocytes: 2.8%, and Basophils: 0.8% higher if compared to the same variable in cows were well maintained. It can be concluded that the Bali cattle grazing in the area of the landfill affected pathophysiological change in its body.

Gambaran Histopatologi Hati dan Ginjal Anjing Terduga Leptospirosis di Kota Denpasar (HISTOPATHOLOGICAL CHANGES OF LIVER AND KIDNEY DOG SUSPECTED CANINE LEPTOSPIROSIS IN DENPASAR CITY) Ida Bagus Oka Winaya; I Ketut Berata; I Made Kardena; Anak Agung Ayu Mirah Adi; Aida Louise Tenden Rompis
Jurnal Veteriner Vol 19 No 2 (2018)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

This study aims to determine the pathological changes in dog suspected of being infected by Leptospira spp. This research used a retrospective study design. A total of 210 canines sample were examined at Faculty of Veterinary Medicine The Udayana of University between January 2008 to January 2010. Of the 210 specimens, five canines with clinical sign anorexia, fever, vomiting, polyurea, dyspnea and only one are noted icteric in the sclera. Macroscopically : the anemic to petechial haemorrhagis was find in pulmo, icterus in liver with gall blader distention, kidney swollen with black color in hillus, spleen rather swollen with black color on end and mild hemorrhagis on intentines. The infected organ is inserted into a pot filled with neutral buffer formalin 10%. Then stained with haematoxyllin-eosin for the microscopic preparation. Microscopic examimination revealed the presence of spiral bacterial cells on the necrotic liver and kidneys tissue. Infiltration neutrophils and macrophages was also find in pulmonary and spleen tissue. Besided that intertubuler edematous were also observed under microscopic examination. It can be concluded changes associated with Leptospira spp infection can be found in liver and kidney tissue with changes such as necrosis, proliferation of kuffer cells and intertubular edematous.

Pneumonia Verminosa pada Kucing Lokal yang Terinfeksi oleh Aelurotsrongylus sp (VERMINOUS PNEUMONIA IN DOMESTIC CAT INFECTED BY AELUROSTRONGYLUS SP) Ida Bagus Oka Winaya; I Ketut Berata; I Made Kardena; Ida Bagus Made Oka
Jurnal Veteriner Vol 13 No 4 (2012)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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The aim of the study was to evaluate the pulmo pathological changes of domestic cat infected byAelurostrongylus sp. A total of 15 cats were examined at Faculty of Veterinery Medicine, Udayana Universityduring 2010. Ten out of 15 cats showed sneezing, whereas the remains showed serous rhinitis and sneezing.Macroscopic and microscopic changes were observed mainly on pulmo samples. Hyperemias on caudalislobes and pleura effusion were found in the pulmo. The pulmo tissue was fixed on 10 % neutral bufferformalin and stained with haematoxilin-eosin (HE) for histopathological examination. Aelurostrongylus spwas present in the alveoli lumen of the lung samples. Meanwhile, the alveoli septa of the lung wereobserved thicker and infiltrated with neutrophils, plasma exudates and erythrocytes. Pleural effusion wasmainly consisted of eosinophilic substances. It is concluded that verminous pneumonia in domestic catinfected with Aelurostrongylus sp was an acute infection.

Perubahan Patologi Sistem Hepatobiliari Sapi Bali Terinfeksi Fasciola gigantica Ida Bagus Oka Winaya; Anak Agung Ayu Mirah Adi; I Ketut Berata; I Made Kardena; Ida Bagus Windia Adnyana; Ida Bagus Kade Suardana
Jurnal Veteriner Vol 21 No 4 (2020)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Liver fluke infections is an important parasitic disease that common attack cattle, buffalo and others ruminant. The disease in the tropics is caused by Fasciola gigantica trematodes. Fasciolosis found in Bali cattle besides causing high economic loss also has the opportunity infect humans. This study aims to determine the pathology changes of Bali cattle hepatobiliary system infected by F. gigantica. In January2019 were examined a hundred of liver tissue Bali cattle. Based on the sex as many as 75 bali cattle are cows and 25 are bulls. On macroscopic examination was found fifteen bali cattles in gallbladder containing of F. gigantica. In positive Fasciolosis the surface of liver look uneven with enlargement of lymph nodes. The tissue of Bali cattle liver infected with F. gigantica is cut into 1x1x1 cm and put in a pot that has been filled with 10% neutral buffered formaline. The fixed tissue then processed in a tissue processor and stained with hematoxylin-eosin (HE). Microscopic examination was found bile ducts proliferation and blocked of the lumen accompanied by cholangio cirrhosis. Found longitudinal pieces of Fasciola giganticaliver fluke surrounded by fibrous connective tissue and multifocal coagulative necrosis with fibroblast proliferation. In some location the infiltration of neutrophil cells around the bile ducts can also be seen. Congestion, bleeding, and neutrophil infiltration are also seen in areas of necrosis. In the bile duct wall bleeding, adenomatus hyperplasia, infiltration of mononuclear cells with mild intensity and foci ofcalcification are found. It can be concluded that there was a change with severe intensity accompanied by chronic inflammation in the hepatobiliary system of Bali cattle with Fasciolosis.

Cemaran Timah Hitam dalam Darah Sapi Bali yang Dipelihara di Tempat Pembuangan Akhir Kota Denpasar (BLOOD LEAD CONTAMINATION IN BALI CATTLE REARED IN THE AREA OF FINAL DISPOSAL OF DENPASAR) I Ketut Berata; Ni Nyoman Werdi Susari; I Made Kardena; I Nyoman Tirta Ariana
Jurnal Veteriner Vol 17 No 4 (2016)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Bali cattle are known for having high adaptability to any environmental condition and have proven tosurvive in critical environments including landfills. The aim of this study was to determine the relationshipbetween Serum Glutamic Pyruvic Transaminase /Serum Glutamic Oxaloacetic Transaminase (SGPT/SGOT) levels and lead (Pb) level in blood of bali cattle reared in the landfill Denpasar. A total of 22Balicattle were used in this study was. The blood was drawn from the jugular vein and 10 ml blood werecollected using tubes containing EDTA 0.5% and 10 mL without EDTA tubes. Levels of SGPT and SGOTwere measured by using Auto analyzer (Refloton (R) plus) method, while the measurement of Pb in bloodplasma was conducted by using atomic absorption spectrophotometry (AAS) method. Result of the SGPTand SGOT measurement obtained were relatively varied with an average of SGPT = 29.96±5.67 U/L andSGOT = 78.82±17.62.U/L. Similarly, Pb measurement results vary widely between 4.004 to 10.216 withan average of 6.595±1.85 ppm. Correlation analysis showed that there was an association between SGOTwith Pb levels. However, no correlation was observed between the SGPT with Pblevels. These resultsindicate that the levels of lead may cause pathological tissue cells in organs other than liver. Its concludedthat heavy metalPb is found in the blood of bali cattle reared in Denpasar city landfill, and it may becorrelated with the level of the SGOT and may cause pathological tissue cells organs.

Co-Authors Afrizal Choirul Umam Agnes Endang Tri H Aida Lousie Tenden Rompis Ainul - Hidayah Alviana Rizqiyah Utami Amelia, Ni Kadek Shita Anak Agung Ayu Mirah Adi Anak Agung Gde Arjana Anak Agung Gde Jaya Wardhita, Anak Agung Gde Jaya Anak Agung Gde Jaya Warditha Anak Agung Oka Anak Agung Sagung Kendran Apsari, Ni Luh Putu Nadia Ardi Sandriya Aristawati, I Dewa Agung Ayu Irma Astari, Ni Putu Widya Astini, Ni Putu Sri Ayu Aulia Insani, Aulia Ayu Prawitasari Citra Pratama Bina Ichsantya Budiartawan, I Komang Alit Damara, Doni Darmawan, I Gusti Ayu Chintya Darmayanti, Mahda Dwi Devira, Dinda Dewa Ayu Dwita Karmi Dhinar Wahyu Prasetyo Dini Hilary Manullang DORTY PRIHASTINA SALBAHAGA Duwiri, Christine Valeri DWI SURYANTO Dzikri Nurma'rifah Takariyanti Elisabeth Karina Elsa Hidayati Elti Febilani Elyda . Erwanti Siti Rabiah, Erwanti Siti Farhan Abdul Hasan, Farhan Abdul Febrianty, Ni Made Dhea Fitri Irawan Rahmawandani Franky Samuel Milenyano Chandra Gde Jasmara Muda Ginting, Regina Bonifasia Br Gunawan, Stefanus Andre Gunawati, Luh Sri Guru, Yohana Cendyka Kartika Dewi Gusti Agung Ayu Putu Adriyati, Gusti Agung Ayu Hendrina Konda M Meha, Hendrina Konda M Humaira, Sarah Husnul Khatimah I Dewa Made Adhiwitana I GEDE ENDRA KUSUMA I Gusti Bagus Sathya Dharma, I Gusti Bagus Sathya I Gusti Ketut Suarjana I Gusti Ngurah Kade Mahardika I Gusti Putu Tovan Mahottama I Ketut Eli Supartika I Ketut Eli Supartika I KETUT ELI SUPARTIKA I Ketut Puja I Ketut Sumadi I Ketut Wirata I Made Damriyasa I Made Indrayadnya Swarayana I Made Kardena I Made Merdana I Made Putra Wiadnyana I Made Sukada I N. T. ARIANA I NYOMAN ADI SURATMA I NYOMAN MANTIK ASTAWA I Nyoman Sulabda I Putu Suparman I W BUDIARSA SUYASA I Wayan Sudira I Wayan Wirata Ida Ayu Pasti Apsari Ida Bagus Kade Suardana Ida Bagus Komang Ardana Ida Bagus Made Oka Ida Bagus Oka Winaya Ida Bagus Windia Adnyana Iwan Harjono Utama Janardani, Ni Made Kunti Jayawardhita, Anak Agung Gde Kadek Karang Agustina Kadek Karina Dewi Wijayanthi Kartika, Erena Hajar Ketut Budiasa Ketut Eli Supartika Ketut Novi Kusmayani Ketut Tono Pasek Gelgel Kevin Dominika Kristi Agusti Putri, Kristi Agusti Kusuma, Putu Winatha Laila Gianita Veralyn Luh Made Sudimartini Lusiana Flora Ndagu Made Oka Adinata Made Rahayu Kusumadewi Marissa Divia Dayanti Marson, Fransiska Gratia Sonita MAS DJOKO RUDYANTO Muhamad Furkam Fadilah Muhsi, Ach Moh Abd Nesia Masniari Helena Sibarani Ni Luh Eka Setiasih Ni Nyoman Werdi Susari Nofantri, Lidia Noviriolla Maria Nugraha, Putri Oktaviandari, Putu Risma Palagan Senopati Sewoyo Pangesti, Thiara A. Pramesti, Ni Komang Lady Prista Oktafebri Yulestari Pujaswarini, Ni Made Hani Purnama, Komang Andika Purnata, I Dewa Nyoman Alit Putra, I Putu Agus Antara Putri Yuliana Mangindaan Putu Agus Trisna Kusuma Antara Putu Suastika Raharjo, Yudha Yaksa Crada Yoga Arum Rahmat Grahadi RAHMI MUSTABA Sam suri Samsuri Samsuri Sari Sartini, Sari Setianingsih, Ni Luh Eka Setyawati, Luh Gede Sewoyo, Palagan Senopati Sihotang, Tanti Fitri Sri Kayati Widyastuti Suranjaya I .Gd Tanuwijaya, Phebe Amadea Vaswani Samaria Napitupulu Wahyu Semadi Putra Waskitha, Melati Pusparini Widia Insani Wulandari, Meidi Andira Yanne Yanse Rumlaklak Yesi Veronica Sitepu Yustisia, Anggia Zumara Mufida Hidayati

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