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All Journal HAYATI Journal of Biosciences International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Jurnal Farmasi Klinik Indonesia Majalah Kedokteran Gigi Indonesia Science and Technology Indonesia Molecular and Cellular Biomedical Sciences (MCBS) Biota Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Bedah Indonesia MAHESA : Malahayati Health Student Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Cancer Makara Journal of Health Research Mulawarman Dental Journal Jurnal Widya Medika
Ahmad Faried
Universitas Padjadjaran
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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Amyotrophic Lateral Sclerosis: First Case Report in Department of Neurosurgery, Faculty of Medicine, Universitas Padjadjaran, Bandung Ahmad Faried; Priandana Adya Eka Saputra; Alief Dhuha; Muhammad Zafrullah Arifin
International Journal of Integrated Health Sciences Vol 7, No 1 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (126.846 KB) | DOI: 10.15850/ijihs.v7n1.1237

Abstract

Objective: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is incurable and results in paralysis of the muscles. Electromyography (EMG) is used to diagnosis amyotrophic lateral sclerosis. Although recently there is no cure for ALS, knowledge has increased significantly in the past several years and is helping those who are newly diagnosed.Methods: This study reported for the first time in Department of Neurosurgery, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin General Hospital, Bandung a 58-year old man who was presented in the institution with a history of weakness of both lower extremities for four months preceded by weakness of both upper extremities since the previous month. There was no history of any medical illness or any chronic medication. The patient then underwent EMG studies, followed by muscle biopsy.Result: Electromyography and histopathological results confirmed a diagnosis of ALS.Conclusion: This case was so exceptional, since ALS occurrence in Neurosurgery Centre is extremely rare, and the diagnosis can only be established through EMG and histopathological of muscle biopsy studies.Keywords: The fist reported of ALS in Neurosurgery Bandung, electromyography studies 
Penetrating Wound in the Skull by a Sharp Metal Object Ahmad Faried; Priandana Adya Eka Saputra; Farid Yudoyono; Muhammad Zafrullah Arifin
International Journal of Integrated Health Sciences Vol 3, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: Penetrating skull injury (PSI) is a neurosurgical emergencies. Most PSI cases reported were caused by gunshot wounds. Although the diagnosis and management of those cases has been described, the actual cases, especially in our center, were quite rare.Methods: A craniectomy debridement with a supine position was performed and removal of the object was achieved. Intraoperatively, we succed control the bleeding as expected.Results: The patient was operated and hospitalized in our center; physical examination revealed neurologically intact before and after the removal of the object. The patient was sent home without any neurological deficits or other complications.Conclusions: We reported a case of penetrating skull injury in a 5-year-old girl caused by a scissors. Penetrating skull injuries were interesting due to its mechanism, management and complications. Early diagnosis and appropriate treatment should resulted in good outcomes.Keywords: Penetrating skull injury, a sharp metal object DOI: 10.15850/ijihs.v3n2.588
Peripheral and Intracranial Compartment Serum Level of Selenium in Pediatric Patients with Intracranial Tumor in Department of Neurosurgery, Faculty of Medicine, Universitas Padjadjaran–Dr. Hasan Sadikin Hospital, Bandung, Indonesia: a Preliminary Study and Literature Review Ahmad Faried; Priandana Adya Eka Saputra; Mirna Sobana; Muhammad Zafrullah Arifin
International Journal of Integrated Health Sciences Vol 4, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: To determine the level of Selenium (Se) in peripheral and intracranial serum in pediatric patients with intracranial tumor. Selenium has chemopreventive potentials and acts as neuromodulator.Methods: This study was conducted on 13 pediatric patients with intracranial tumors who were treated in Dr. Hasan Sadikin Hospital, Bandung in the period of February 2014 to February 2015. Samples were taken from peripheral and intracranial serum. The results were analyzed with independent t-test and Pearson correlation test. Significance is defined as p≤0.05 with 95% confidence interval.Results: The results showed that the average Se concentration in peripheral serum was significantly higher than the Se concentration in intracranial serum (95.92±20.95 μg/L and 66.62±22.37 μg/L, respectively). After classifying the subjects into groups based on sex, age, tumor location, and grades, the difference between Se concentrations were still statistically significant (p≤0.05), with the exception of the supratentorial group (p=0.0053). Pearson correlation test showed very-low to medium strength correlations between peripheral and intracranial serum Se concentration in all groups (r=0.16–0.59, p>0.05).Conclusions: A significant difference is seen between the peripheral and intracranial serum Se concentration means in pediatric patients with intracranial tumors, with higher concentrations observed in the peripheral serum. Further studies are required to investigate the roles of Se in the management of pediatric patients with intracranial tumors.Keywords: Pediatric intracranial tumor patients, selenium concentration in peripheral and intracranial serum DOI: 10.15850/ijihs.v4n2.835
Characteristics of Cerebrospinal Fluid in Tuberculous Meningitis Patients with Hydrocephalus Astrid Tamara Maajid Budiman; Nida Suryana; Ahmad Faried; Ida Parwati
International Journal of Integrated Health Sciences Vol 6, No 2 (2018)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: To describe cerebrospinal fluid (CSF) characteristics in tuberculous meningitis (TBM) with hydrocephalus patients as diagnostic criteria of TBM.Methods: A cross-sectional using retrospective method was applied in this study by obtaining medical records of TBM with hydrocephalus patients that were treated at Department of Neurosurgery Dr. Hasan Sadikin General Hospital, Bandung from January 2014–September 2016. Results: Sixty one records were included in the study. Patient characteristics such as age, gender, and CSF laboratory features such as color and clarity, cells and differential count, protein, and glucose were recorded and descriptively analyzed. The majority of CSF macroscopic appearance was seen to be clear (88%) and colorless (88%). Median for CSF cell count was 25 cells/mm3 with lymphocyte predominance (median: 76%). Increased protein from normal value range was seen in CSF (median: 50 mg/dL) while the mean for CSF glucose in this study remained in its normal value range (mean: 58.9±26.68 mg/dL) with lower CSF to blood glucose ratio (mean: 0.41±0.27).Conclusions: Clear CSF with colorless appearance, lymphocyte pleocytosis, high protein level, and low CSF glucose as well as blood glucose ratio remain typical CSF characteristics of TBM patients found at the Department of Neurosurgery, Dr. Hasan Sadikin General Hospital, Bandung. Keywords: Cerebrospinal fluid, hydrocephalus, tuberculous meningitis DOI: 10.15850/ijihs.v6n2.1129
Correlation between Degree of Gibbus Angulation, Neurological Deficits, and Pain in Spondylitis Tuberculosis Patients Rizkiditia Nugraha Hadian; Renaldi Prasetia; Ahmad Faried
International Journal of Integrated Health Sciences Vol 5, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: To analyze the correlation between the degree of angulation and neurological deficits as well as pain in spondylitis tuberculosis (TB) patients.Methods: This observational-analytic study included bivariate analysis on data collected from the medical records of patients with presented with spondylitis TB to Dr. Hasan Sadikin General Hospital, Bandung outpatient clinic from January 2014 to December 2015. The variables were the degree of gibbus angulation, neurological deficits, and pain.Results: The study showed significant positive correlation between gibbus angulation and sensory neurological deficits (r=0.375; p=0.009) and there was significant positive correlation between gibbus angulation and pain (r=0.638, p=0.000). The study showed an insignificant correlation between gibbus angulation and motoric neurological deficits (r=0.125; p=0.525).Conclusions: There is a significant correlation between the degree of gibbus angulation and pain as well as sensory neurological deficits. Meanwhile, no significant correlation is found between the degree of gibbus angulation and motoric neurological deficits.Keywords: Gibbus angulation, neurological deficits, pain, spondylitis tuberculosis DOI: 10.15850/ijihs.v5n2.1049
Morphometric Analysis of the Corpus, Spinal Canal and Torg Ratio Using Midsagittal Cervical Vertebrae Computed Tomography Scan: Indonesian Population Rully Hanafi Dahlan; Priandana Adya Eka Saputra; Farid Farid Yudoyono; Sevline Esthetia Ompusunggu; Muhammad Zafrullah Arifin; Agung Budi Sutiono; Ahmad Faried
International Journal of Integrated Health Sciences Vol 2, No 1 (2014)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: To determine the normal ranges of cervical spinal canal morphometry in Indonesian population and to compare the acquired data collected from other populationsMethods: Computed tomography measurements on the diameter of midsagital spinal canal and corpus of cervical vertebrae and its Torg ratio from the lower cervical (C3-C7) canal from 24 normal Indonesian adults were performed at the Radiology Department of Dr. Hasan Sadikin General Hospital. Patients who had cervical spine disorders and those under 20 years old were exluded.  We used computed tomography scan midsagittal view to measure the aforementioned parameters.    Results: The average diameter for the cervical spinal canals for the Indonesian population is comparable with those of other Asian populations such as Hongkong and India, albeit with smaller Torg ratio.     Conclusions: This study reports the normal radiological anatomy of the midsagital spinal canal and corpus of cervical vertebrae as well as Torg ratio from the lower cervical vertebrae among Indonesian population. The measurements result of this study shows that, although slightly smaller, the measurement results for those parameters are identical with other Asian populations.    Keywords: Corpus cervical vertebrae, midsagittal cervical spinal canal, Torg ratio DOI: 10.15850/ijihs.v2n1.285
Rare Distal Anterior Choroidal Artery Aneurysm Muhammad Zafrullah Arifin; Julius July; Bilzardy Ferry; Ahmad Faried
International Journal of Integrated Health Sciences Vol 4, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: To describe a rare patient with ruptur aneurysm case of distal anterior choroidal artery (AChA) and intraventricular hemorrhage. A 56-year old female came to our hospital with chief complaint sudden onset of severe headache and vomiting.Methods: Head computed tomography (CT)-scan and angiography on the lesion was performed at the Department of Radiology, Siloam Hospital, Tangerang, Indonesia.Results: Head CT-scan imaging revealed an intraventricular hemorrhage, primarily in the right lateral ventricle, with slight enlargement of both lateral, 3rd and 4th ventricles. Angiography examination revealed a round vascular lesion at the wall of the posterior cornu of the lateral ventricle and an occlusion of the M1 base segment of the left middle cerebral artery.Conclusions: The lesion, distal AChA aneurysm, at the posterior cornu was reached using an infratemporal lobe approach with the help of neuronavigation. Microsurgical clipping was successfully performed.Keywords: Aneurysm, distal anterior choroidal artery, neuronavigation DOI: 10.15850/ijihs.v4n2.837
Serum Selenium Concentration in Cervical Cancer Patients: Preliminary Study and Literature Review Leri Septiani; Yudi Mulyana Hidayat; Mutakin Mutakin; Rizky Abdulah; Ahmad Faried; Hiroshi Koyama
International Journal of Integrated Health Sciences Vol 4, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: To analyze the role of selenium and glutathione peroxidase (GPx) in cervical cancer.Methods: Serum selenium concentrations and GPx activities of 19 women with cervical cancer along with their healthy counterparts (control group) were obtained. Selenium concentration were measured fluorometrically and GPx activities were measured spectrophotometrically based on the quantity of NADPH used in the reduction of glutathione. Results: The mean of serum selenium concentrations in cervical cancer group was significantly lower than that in the control group, 67.24±15 ng/mL and 77.05±12 ng/mL (p=0.03), respectively. The mean GPx activity in the cervical cancer group was also significantly lower than that in the control group, 128.18±38 ∆mmol NADPH/min/L and 148.9±23 ∆mmol NADPH/min/L (p=0.04), respectively. Multivariate analysis in the cervical cancer patients showed that the Fédération Internationale de Gynécologie et d’Obstétrique (FIGO) staging score (early vs. advanced) was inversely correlated with serum selenium concentration (p=0.027).Conclusions: Serum selenium concentration and GPx activity was significantly lower in the cervical cancer patients. Our results demonstrate that selenium and GPx activity may have an important role in the carcinogenesis of cervical cancer. Keywords: Cervical cancer, glutathione peroxidase activity, selenium DOI: 10.15850/ijihs.v4n2.833
Anterior Interhemispheric Approach for Olfactory Groove Meningioma Imam Hidayat; Agung Budi Sutiono; Ahmad Faried; Muhammad Zafrullah Arifin
International Journal of Integrated Health Sciences Vol 4, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: To evaluate the surgical technique with bifrontal interhemispheric approach for total removal of tumor in olfactory groove meningioma (OGM). Methods: This study described a case of a 38-year-old woman with bilateral blindness, anosmia, and behaviour changes. Imaging studies show a tumor mass in midfrontal base. Surgery using a bifrontal interhemispheric approach was performed and total removal was achieved and postoperative computed tomography (CT) scan was performed to confirm the result. Histopathological findings established a diagnosis of meningioma.Results: A coronal skin incision behind the hairline was utilized. The scalp was elevated, taking care to reserve the vascularized pericranium medial to the linea temporalis of each side, and preserving the 2 supraorbital nerves. Eight burr holes were used, with the two initial holes made on each side of the orbitotemporal region, and the other four holes at the midline. A bifrontal craniotomy was performed. The tumor was first detached from its attachment with bipolar cautery and debulked. During this step, the main tumor feeder arteries from the anterior and posterior ethmoidal artery were interrupted, and the tumor devascularized. Total tumor removal through surgical intervention was achieved and confirmed by head CT-scan postoperatively.Conclusions: This case report supports the suitability of the bifrontal interhemispheric approach for OGM resection with additional radiation therapy.Keywords: Anterior interhemispheric approach, olfactory groove meningioma DOI: 10.15850/ijihs.v4n2.838
Cystic Meningioma in the Inter-Hemisferic Space Location Muhammad Zafrullah Arifin; Firman Priguna Tjahjono; Agung Budi Sutiono; Ahmad Faried
International Journal of Integrated Health Sciences Vol 4, No 1 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objective: The presentation of cystic meningioma in the inter-hemispheric near the falx cerebri is uncommon. It is difficult to differentiate it from intra-axial tumors, such as gliomas. Therefore, it is likely that it is misdiagnosed as other types of brain tumors.Methods: In this study, we reported a cystic meningioma case in the inter-hemispheric location, showing an intramural nodule on magnetic resonance imaging scans.Results: Patient underwent surgical treatment and pathological section confirmation revealing meningioma. The patient was a middle-age woman and had been misdiagnosed as suffering from glioma followed by slight hemipharesis on the right extremities.Conclusions: Although this is a rare case, it will be good if we always consider cystic meningioma in inter-hemispheric space when diagnosing this type of cystic lesion if the magnetic resonance imaging (MRI) shows a cystic lesion mimicking glioma image presentation.Keywords: Cystic meningioma, interhemispheric space, magnetic resonance imaging, diagnosis DOI: 10.15850/ijihs.v4n1.686
Co-Authors . SETIAWAN Achadiyani Adriani Lawrencia Novalia Afiat Berbudi Agung B Sutiono Agung Budi Sutiono Agung Budi Sutiono Agung Budi Sutiono Agus Dwi Sastrawan Ajeng Diantini Alya Mardhotillah Azizah Amarila Malik Amelia Ganefianty Amira Puti Karima ANDI WIJAYA Angliana Chouw Angliana Chouw, Angliana Astrid Tamara Maajid Budiman Azis, Rizal Ban Bolly, Hendrikus Masang Bayu W. Putera Benny Atmadja Wirjomartani Benny Isakh Beny Atmadja Wirjomartani Bethy Surjawathy Hernowo Billy Parulian Lubis Bilzardy Ferry Cynthia R. Sartika Cynthia Retna Sartika, Cynthia Retna Daniel Happy Putra Danny Halim Dedy Kurniawan Derrett, Sarah Dhuha, Alief Dian Ratih Laksmitawati Diana Krisanti Jasaputra Didik Priyandoko Dimas Erlangga Luftimas Dimyati Achmad Dumingan, Alvian Dwi A. P. Dewi Dwi Davidson Rihibiha Endang Sjamsudin Endang Sjamsudin Ermi Girsang Ervi Afifah Fahmi, Ismail Farid Yudoyono Firman Fuad Wirakusumah Firman Priguna Tjahjono Ganefianty, Amelia Gill, Arwinder Singh Ginting, Chrismis Novalinda Haifa, Rima Hanna Sari W Kusuma Hanna Sari Widya Kusuma Hapsari, Putie Harry Murti Harry Murti Hasrayanti Agustina Heda Melinda Nataprawira Hendrikus Bolly Hendrikus Masang Ban Bolly Hermin Aminah Usman Hiroshi Koyama Huda, Fathul I M Kariasa I Made Kariasa I Nyoman Ehrich Lister Ida Parwati Indah, Astrina Rosaria Indra Bachtiar Ismail Fahmi Jeffrey ., Jeffrey Jefri Henky Julia Riswandani Julius July Kahdar Wiriadisastra Kalih Sarjono Kharisma, Surti Wulan Leri Septiani Maman Abdurrahman Maryani, Euis McAllister, Susan MEILINAH HIDAYAT Melia, Regina Melisa Intan Barliana, Melisa Intan Mirna Sobana Mochammad Aris Widodo MUCHTAN SUJATNO Muhammad Firdaus Muhammad Kusdiansah Muhammad Z. Arifin Muhammad Zafrullah Arifin Mutakin Mutakin Nainggolan, Ita Margaretha Nida Suryana Noverina, Rachmawati NUGRAHA SUTADIPURA Priandana Adya Eka Saputra Priandana Adya Eka Saputra Purwaningtyas, Yoggi Ramadhani Qlintang, Sandy Rachmawati Noverina Rachmawati Noverina Raden Yohana, Raden RAHMAT, DENI Ratih Rinendyaputri Ratih Rinendyaputri Rayhani, Farilaila Renaldi Prasetia Reni Ghrahani Rilianawati Rilianawati Rini Andriani Rizal Rizal Rizal Rizal Rizki, Kiki Ahmad Rizkiditia Nugraha Hadian Rizky Abdulah Robert Sinurat Rully Hanafi Dahlan Sarah Derrett Sarjono, Kalih Seila Arumwardana Sevline Esthetia Ompusunggu Singh, Arwinder Sobana, Mirna Soeprajogo, Adolf Setiabudi Solly Aryza Sri Suryanti Subangkit, Mawar Sugiarto, Yosafat Kurniawan Sunarno Sunarno Susan McAllister Sutiman Bambang Sumitro Sutiono, Agung B Syahril Samad, Syahril Syamsiar, Syamsiar Takayuki Ohira Takeshi Kawase Teguh Marfen Djajakusumah, Teguh Marfen Teresa Liliana Wargasetia The Fransiska Eltania Tinambunan, Nicholas Christian Tono Djuwantono Tono Djuwantono Trajanus Laurens Yembise Tri Hanggono Achmad Triharsiwi, Dwi Nur Utama, Hieronimus Adiyoga Nareswara Vinna Kurniawati Sugiaman, Vinna Kurniawati Wahyu Widowati Wahyu Widowati Wahyu Widowati WAHYU WIDOWATI Widarta, Oskar Ady Wireni Ayuningtyas Yarman, Indra Prasetya Yudi Mulyana Hidayat Yuni Elsa Hadisaputri Yusuf Hariady Hariady Yusuf Sulaeman Effendi