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All Journal Jurnal Gizi dan Pangan Jurnal Kesehatan Andalas Paediatrica Indonesiana Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Indonesian Journal of Obstetrics & Gynecology Science Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Penyakit Dalam Indonesia Jurnal Sains, Teknologi dan Kesehatan
Efrida Efrida
Bagian Patologi Klinik Dan Kedokteran Laboratorium, Fakultas Kedokteran, Universitas Andalas, Padang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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Leukositosis, Neutrofilia, Radiologi Pneumonia, dan Usia Lanjut sebagai Faktor Risiko Derajat Kritis Pasien COVID-19 di Rumah Sakit Semen Padang : Studi Kasus Kontrol Efrida, Efrida
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Supplementary July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i5.p805-812.2023

Abstract

Latar Belakang: Pandemi Coronavirus Disease 2019 (COVID-19) disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), telah menyebabkan morbiditas dan mortalitas yang tinggi di seluruh dunia. Banyaknya kasus terkonfirmasi di seluruh dunia mendorong pemahaman komprehensif tentang faktor risiko COVID-19, sehingga dapat membantu pencegahan penyakit, perkembangan penyakit, dan hasil yang dapat merugikan pasien. Tujuan: Menganalisis faktor risiko yang berhubungan dengan derajat keparahan penyakit pasien COVID-19 di Rumah Sakit Semen Padang. Metode: Penelitian ini merupakan penelitian analitik observasional dengan pendekatan case-control menggunakan 100 data rekam medis pasien COVID-19 yang dirawat di Rumah Sakit Semen Padang pada tahun 2021. Parameter yang diperiksa berupa komorbid, rontgen foto toraks, dan parameter labor yaitu leukosit, neutrofil, limfosit, RNL, dan D-dimer. Teknik pengambilan sampel adalah consecutive sampling. Analisis bivariat menggunakan uji Chi-Square. Hasil dianggap bermakna jika nilai p<0,05. Hasil: Karakteristik pasien rawatan COVID-19: laki-laki sebanyak 51% dan perempuan 49%, kelompok umur lansia (>60 tahun) sebanyak 45%, 65% pasien memiliki komorbid, 63% pasien memiliki hasil pemeriksaan radiologi pneumonia. Hasil penelitian ini menunjukkan terdapat hubungan antara kelompok umur, hasil pemeriksaan radiologi, jumlah leukosit, dan jumlah neutrofil dengan derajat keparahan pasien COVID-19. Simpulan: Kelompok umur lansia, radiologi pneumonia, leukositosis, dan neutrofilia menjadi faktor risiko pasien COVID-19 derajat kritis di Rumah Sakit Semen Padang tahun 2021.
Association of Vitamin D with Insulin Resistance and Pancreatic β-Cell Function in Non-Diabetic Obese Staff: A Cross-Sectional Study Efrida, Efrida; Putri, Dian Eka; Yaswir, Rismawati; Lipoeto, Nur Indrawati; Zhuhra, Rahma Tsania; Almurdi, Almurdi
Jurnal Gizi dan Pangan Vol. 20 No. 3 (2025)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jgp.2025.20.3.209-218

Abstract

This research explored whether vitamin D status is related to Insulin Resistance (IR) and pancreatic β-cell performance among non-diabetic obese employees at Dr. M. Djamil Padang Hospital, West Sumatra, Indonesia. Insulin resistance and β-cell activity were assessed using the Homeostatic Model Assessment—specifically Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) as an indicator of insulin resistance and Homeostasis Model Assessment of Beta-Cell Function (HOMA-B) to evaluate β-cell function. The study applied a cross-sectional design conducted from January to July 2020 and involved 81 obese hospital staff without diabetes. Measurements included Fasting Blood Glucose (FBG), Fasting Insulin (FI), and Serum 25-Hydroxyvitamin D [25(OH)D], all analyzed with automated instruments. HOMA-IR and HOMA-B indices were derived from FBG and FI using standard formulas. Statistical analysis used the Spearman correlation test with a significance threshold of p<0.05, followed by multivariate linear regression. The participants were predominantly female (58%), aged 18–58 years, with a mean Body Mass Index (BMI) of 31.46±3.99 kg/m². Average vitamin D levels were 14.84±5.48 ng/mL, while median values for HOMA-IR and HOMA-B were 2.30 and 193.09%, respectively. The results indicated that vitamin D concentrations did not show a meaningful correlation with either HOMA-IR (r=0.071; p=0.530) or HOMA-B (r=−0.106; p=0.347). BMI demonstrated the strongest association with HOMA-IR (β=0.165), and HOMA-IR was the variable most strongly related to HOMA-B (β=21.83). Overall, this study concludes that baseline vitamin D levels are not significantly linked to insulin resistance or pancreatic β-cell function, as reflected by HOMA-IR and HOMA-B measurements, among non-diabetic obese staff at Dr. M. Djamil Padang Hospital.
Co-Authors A.A. Ketut Agung Cahyawan W Ade Asyari Afriwardi Afriwardi Aghnia Jolanda Putri Akmal M. Hanif Al Hafiz Almurdi Almurdi Alya Binti Azmi Amirah Zatil Izzah Andani E Putra Andani Eka Putra Angela Lovena Anggun Hatika Riska Arnelis Arnelis Asman Manaf Asterina Asterina Bakma, Isphandra Besri, Hanifa Zahra Bestari Jaka Budiman Desmawati Desmawati Desywar Desywar Desywar Desywar Desywar Desywar Desywar, Desywar Devi Gusmaiyanto Dia Rofinda, Zelly Dia Dian Eka Putri Dian Eka Putri, Dian Eka Dian Pertiwi Dian Pertiwi Dona Mirsa Putri Donaliazarti Donaliazarti Dwi Amelisa Edwina Dwi Yulia Dwitya Elvira, Dwitya Effy Huriyati Efiariza, Nurul Navela Ega Purnamasari Eka Musmita Sabebegen Eka Nofita Elisda Yusra Ellyza Nasrul Ellyza Nasrul Elmatris Sy Elvinawaty Elvinawaty Endang Primawaty Harahap Endrinaldi Eryati Darwin Eti Yerizel Ety Yerizel Eugeny Alia Fachzi Fitri Fadil Oenzil Fathiyyatul Khaira, Fathiyyatul Febria Prima Utari Finny Fitry Yani Fiona Septi Mulya Fitria, Syarifah Tridani Fitrina, Dewi Wahyu Hanifah Maani Hanny Hafiar Harahap, Endang Primawaty Hasmiwati Hendra Permana Herman, Deddy Husni Husni Husnil Kadri Ida Parwati Ike Sri Redjeki Ilhamifithri Ilhamifithri Ilmiawati, Ilmiawati Ima Septia Indah Fitriani Isphandra Bakma Jacky Munilson Jamsari Jamsari Kartika Aulia Sari Lestari, Rahmi Lillah Lillah Malinda Meinapuri Masrul Basyar Masrul Syafri Mefri Yanni Mega Redha Putri Mira Purwinanty Mohamad Reza Mulya, Fiona Septi Nanda Oktavia Narlis Narlis Netti Suharti Nirza Warto Novialdi . Nur Afrainin Syah Nur Indrawati Lipoeto Nur Indrawaty Lipoeto Nuzulia Irawati Oktavia, Nanda Prihandani, Tuty Prima O Damhuri Puja, Annisa Fitria Putri Yuriandini Yulsam Rahmadina, Rahmadina Rahmatini . Ramadhani, Jihan Regina Ivanovna Rendi Dwi Prasetyo Reni Lenggogeni Rikarni Rikarni Rike Puspasari Rismawati Yaswir Rizanda Machmud Rizqy Auliya Lubis Rossy Rosalinda Roza Kurniati Rudy Afriant Russilawati, Russilawati Sabebegen, Eka Musmita Saptino Miro Sari, Kartika Aulia Selfi Renita Rusjdi Siti Nurhajjah Sofitri Sofitri Suchi Ilmi Herman Sukri Rahman Syarifah Tridani Fitria Trisuliandre, Muhammad Rizki Tuty Prihandani Ulya Uti Fasrini Vanny Syafitri Vika Rahma Velina Yan Edward Yulia, Dwi Yulistini, Yulistini Yusrawati Yusrawati Yusri Dianne Jurnalis Yustini Alioes Zahira, Aisyah Dhia Zelly Dia Rofinda Zhuhra, Rahma Tsania