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All Journal DIKSI Jurnal Manajemen Pendidikan LingTera Dusturiah : Jurnal Hukum Islam, Perundang-undangan dan Pranata Sosial Jurnal Penelitian Pendidikan IPA (JPPIPA) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Perspektif Ilmu Pendidikan VISI : Jurnal Ilmiah Pendidik dan Tenaga Kependidikan Pendidikan Non Formal Martabe : Jurnal Pengabdian Kepada Masyarakat Lectura : Jurnal Pendidikan Journal of Educational Research and Evaluation Jurnal Ilmiah Pendidikan Profesi Guru JUARA : Jurnal Olahraga JURNAL KESEHATAN INDRA HUSADA IMPROVEMENT: Jurnal Ilmiah untuk peningkatan mutu manajemen pendidikan Jurnal Simbur Cahaya SOSIOEDUKASI : JURNAL ILMIAH ILMU PENDIDIKAN DAN SOSIAL Edunesia : jurnal Ilmiah Pendidikan JURNAL LITERASI OLAHRAGA Ainara Journal (Jurnal Penelitian dan PKM Bidang Ilmu Pendidikan) Journal for Lesson and Learning Studies Journal of Educational Management and Instruction (JEMIn) Transformasi dan Inovasi : Jurnal Pengabdian Masyarakat JANITA Indonesian Journal of Economics and Management Journal of Student Development Informatics Management (JoSDIM) Journal of Educational Sciences International Review of Practical Innovation, Technology and Green Energy (IRPITAGE) PERDULI: Jurnal Pengabdian kepada Masyarakat ITQAN: Journal of Islamic Economics, Management, and Finance Jurnal Pendidikan Islam Journal Research of Social Science, Economics, and Management International Education Trend Issues Nanggroe: Journal Of Scholarly Service Jurnal Pengabdian Masyarakat Bangsa Jurnal Kajian dan Penelitian Umum International Journal of Economics, Management and Accounting Beginner: Journal of Teaching and Education Management Nanggroe: Journal of Scholarly Service Jurnal Media Akademik (JMA) Moneter : Jurnal Ekonomi dan Keuangan GENIUS: Indonesian Journal of Early Childhood Education Journal Boas : Business, Economics, Accounting And Management Medical Sains : Jurnal Ilmiah Kefarmasian Nusantara Mengabdi kepada Negeri International Journal of Business and Quality Research Jurnal Riset Multidisiplin Edukasi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Business, Entrepreneurship, and Management Journal JUARA
Desi Rahmawati
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Journal : Medical Sains : Jurnal Ilmiah Kefarmasian

 1 
ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF TARO LEAVES (Colocasia esculenta (L.) Schott) AND ITS FRACTIONS IN RATS USING EGG WHITE-INDUCED MODEL Sujono, Tanti Azizah; Rahmawati, Desi
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1316

Abstract

Taro plant (Colocasia esculenta (L.) Schott) is empirically known to have anti-inflammatory activity. Taro leaves contain secondary metabolites such as alkaloids, saponins, tannins, flavonoids, and polyphenols. This study aimed to prove the anti-inflammatory effectiveness of ethanol extract of taro leaves (EETL), ethyl acetate fraction (EAFTL), and residual fraction (RFTL) in rats induced by 1% egg white solution, and to identify the chemical compound groups contained in EETL and its fractions. Thirty-two rats were divided into eight groups, namely group I as a negative control (CMC-Na 0.5%), group II as a positive control (Diclofenac sodium 4.5 mg/kgBW), groups III-IV were administered EETL 100 and 200 mg/kgBW, groups V-VI were administered EAFTL 100 and 200 mg/kgBW, and groups VII-VIII were administered RFTL 100 and 200 mg/kgBW. The animal models were induced with 0.1 mL of 1% egg white solution subplantar 1 hour after oral treatment. The volume of rat leg edema was measured every 1 hour for six consecutive hours. This research shows that EETL 100 mg/kgBW and RFTL doses of 100 and 200 mg/kgBW have an anti-inflammatory effect with a percent inhibitory power of >50%. Phytochemical screening showed that EETL contains alkaloids, saponins, tannins, and phenolics. EAFTL contains tannins and phenolics, whereas RFTL contains saponins, tannins, and phenolics.  Keywords: Taro leaves, antiinflammatory, egg white solution, fractionation
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