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All Journal HAYATI Journal of Biosciences Jurnal Ilmiah Farmasi Indonesian Journal of Cancer Chemoprevention Majalah Obat Tradisional Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Syntax Literate: Jurnal Ilmiah Indonesia Majalah Farmaseutik Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Holistik Jurnal Kesehatan Jurnal Farmasi Indonesia JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Biomedika dan Kesehatan Poltekita : Jurnal Ilmu Kesehatan Majalah Farmasetika To Maega: Jurnal Pengabdian Masyarakat Jurnal Farmamedika (Pharmamedica Journal) SULUH: Jurnal Abdimas Health Information : Jurnal Penelitian Jurnal Kesehatan Poltekkes Kemenkes RI Pangkalpinang Jurnal Kefarmasian AKFARINDO Jurnal Kesehatan Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Farmagazine Jurnal Buana Farma Binawan Student Journal Journal of Social Research East Asian Journal of Multidisciplinary Research (EAJMR) International Journal of Health and Pharmaceutical (IJHP) Sciences of Pharmacy Jurnal Farmasi Indonesia Kartika : Jurnal Ilmiah Farmasi Jurnal Kefarmasian Indonesia Jurnal Sains dan Kesehatan Journal of Natural Product for Degenerative Diseases Akurasi Jurnal Kesehatan
Dian Ratih Laksmitawati
Universitas Pancasila
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Aktivitas Ekstrak Daun Binahong(Anredera cordifolia (Ten.) Steenis) sebagai Antihiperurisemia dan Antioksidan pada Tikus Hiperurisemia Laksmitawati, Dian Ratih; Simbolon, Roslan
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 9, No 1 (2017): Punica Granatum
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT : The Binahong plant (Anredera cordifolia (Ten.) Steenis) has been used to treat several types of diseases. To find another possible biological activities, we investigated binahong leaves antihyperuricemic and antioxidant activity through in vitro assay of xanthine oxidase inhibiting activity of binahong ethanol extract and through in vivo assay by measuring uric acid and malondialdehyde (MDA) levels in plasma of hyperuricemic rat treated with binahong ethanol extract. Rat was induced into hyperuricemiccondition using chicken concentrate which is administered orally for 7 days and potassium oxonic through intraperitoneal routeon the last day. In treatment groups, rat were administered with extract at doses 200, 400 and 800 mg/kg BW respectively along the induction periods, while theother group were given allopurinol. On 7thday, the levels of plasma uric acid andMDA were measured by enzymatic methods and tiobarbituric acid reactive substances (TBARS) methodconsecutively. In vitro study shows that at 100 ppm,binahong leavesethanolic extract inhibit xanthine oxidase activity by24.33%, while in vivo study showedthe extract hadantihyperuricemic activity by decreasinguric acid levels at dose 800 mg / kgBB about 60,88% compared to hyperuricemia control group. Plasma MDA levels showed that hyperuricemia induction for 7 days was not enough to show significant increase of MDA levels.As conclusion, the ethanolic extract of binahong leaves could lower uric acid levels but in this study  it’s activity as antioxidant could not be proven through MDA measurements.
Nilai Indeks Glikemik dan Indeks Transit Usus Tepung Porang (Amorphophallus muelleri Blume.) pada Mencit Putih Laksmitawati, Dian Ratih; Prilasari, Sharon Alia; Marwati, Umi
Jurnal Farmasi Indonesia Vol 9, No 2 (2017)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v9i2.577

Abstract

To prevent hyperglycemia, people need alternative source of carbohydrate with low glycemic index. Porang bulbs from Amorphophallus muelleri Blume plant is rich on glucomannan, that could prevent elevation of blood glucose level. The aim ofthis study is to determine aglycemic index and intestinal transit index of porang bulbs flour. Glycemic index determined by glucose tolerance test method and intestinal transit index determined by measuring the intestinal transit distance of mice administered 1,5 kg BW intragastically the porang suspense. Forty-five minute later mice was given carbo absorben as a marker. At 15 minute later mice was sacrificed by cervical dislocation and the distance of charcoal marker was measure from pillory. The results shows that porang has glycemic index 85 compare with glucose 100 and treatment with porang flour caused the intestinal motility was faster (intestinal transit index -0,42) rather than wheat four (0,32). Its mean that, porang flour shorten the retention time of chymus in intestinum s0 it will inhibit the absorbtion of'glucose. To prevent hyperglycemia, people need alternative source of carbohydrate with low glycemic index. Porang bulbs from Amorphophallus muelleri Blume plant is rich on glucomannan, that could prevent elevation of blood glucose level. The aim ofthis study is to determine aglycemic index and intestinal transit index of porang bulbs flour. Glycemic index determined by glucose tolerance test method and intestinal transit index determined by measuring the intestinal transit distance of mice administered 1,5 kg BW intragastically the porang suspense. Forty-five minute later mice was given carbo absorben as a marker. At 15 minute later mice was sacrificed by cervical dislocation and the distance of charcoal marker was measure from pillory. The results shows that porang has glycemic index 85 compare with glucose 100 and treatment with porang flour caused the intestinal motility was faster (intestinal transit index -0,42) rather than wheat four (0,32). Its mean that, porang flour shorten the retention time of chymus in intestinum s0 it will inhibit the absorbtion of'glucose.
Nilai Indeks Glikemik dan Indeks Transit Usus Tepung Porang (Amorphophallus muelleri Blume.) pada Mencit Putih Laksmitawati, Dian Ratih; Prilasari, Sharon Alia; Marwati, Umi
Jurnal Farmasi Indonesia Vol 9, No 2 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1059.97 KB) | DOI: 10.35617/jfi.v9i2.577

Abstract

To prevent hyperglycemia, people need alternative source of carbohydrate with low glycemic index. Porang bulbs from Amorphophallus muelleri Blume plant is rich on glucomannan, that could prevent elevation of blood glucose level. The aim ofthis study is to determine aglycemic index and intestinal transit index of porang bulbs flour. Glycemic index determined by glucose tolerance test method and intestinal transit index determined by measuring the intestinal transit distance of mice administered 1,5 kg BW intragastically the porang suspense. Forty-five minute later mice was given carbo absorben as a marker. At 15 minute later mice was sacrificed by cervical dislocation and the distance of charcoal marker was measure from pillory. The results shows that porang has glycemic index 85 compare with glucose 100 and treatment with porang flour caused the intestinal motility was faster (intestinal transit index -0,42) rather than wheat four (0,32). Its mean that, porang flour shorten the retention time of chymus in intestinum s0 it will inhibit the absorbtion of'glucose. To prevent hyperglycemia, people need alternative source of carbohydrate with low glycemic index. Porang bulbs from Amorphophallus muelleri Blume plant is rich on glucomannan, that could prevent elevation of blood glucose level. The aim ofthis study is to determine aglycemic index and intestinal transit index of porang bulbs flour. Glycemic index determined by glucose tolerance test method and intestinal transit index determined by measuring the intestinal transit distance of mice administered 1,5 kg BW intragastically the porang suspense. Forty-five minute later mice was given carbo absorben as a marker. At 15 minute later mice was sacrificed by cervical dislocation and the distance of charcoal marker was measure from pillory. The results shows that porang has glycemic index 85 compare with glucose 100 and treatment with porang flour caused the intestinal motility was faster (intestinal transit index -0,42) rather than wheat four (0,32). Its mean that, porang flour shorten the retention time of chymus in intestinum s0 it will inhibit the absorbtion of'glucose.
Aktivitas Ekstrak Daun Binahong(Anredera cordifolia (Ten.) Steenis) sebagai Antihiperurisemia dan Antioksidan pada Tikus Hiperurisemia Laksmitawati, Dian Ratih; Simbolon, Roslan
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (7559.601 KB) | DOI: 10.35617/jfi.v9i1.556

Abstract

ABSTRACT : The Binahong plant (Anredera cordifolia (Ten.) Steenis) has been used to treat several types of diseases. To find another possible biological activities, we investigated binahong leaves antihyperuricemic and antioxidant activity through in vitro assay of xanthine oxidase inhibiting activity of binahong ethanol extract and through in vivo assay by measuring uric acid and malondialdehyde (MDA) levels in plasma of hyperuricemic rat treated with binahong ethanol extract. Rat was induced into hyperuricemiccondition using chicken concentrate which is administered orally for 7 days and potassium oxonic through intraperitoneal routeon the last day. In treatment groups, rat were administered with extract at doses 200, 400 and 800 mg/kg BW respectively along the induction periods, while theother group were given allopurinol. On 7thday, the levels of plasma uric acid andMDA were measured by enzymatic methods and tiobarbituric acid reactive substances (TBARS) methodconsecutively. In vitro study shows that at 100 ppm,binahong leavesethanolic extract inhibit xanthine oxidase activity by24.33%, while in vivo study showedthe extract hadantihyperuricemic activity by decreasinguric acid levels at dose 800 mg / kgBB about 60,88% compared to hyperuricemia control group. Plasma MDA levels showed that hyperuricemia induction for 7 days was not enough to show significant increase of MDA levels.As conclusion, the ethanolic extract of binahong leaves could lower uric acid levels but in this study  itâ??s activity as antioxidant could not be proven through MDA measurements.
PENGARUH ELECTRONIC WORD OF MOUTH (E-WOM) DAN BRAND IMAGE TERHADAP KEPUTUSAN PEMBELIAN PRODUK IMMUNOMODULATOR (PENELITIAN DI WILAYAH DKI JAKARTA) Maulina, Novia; Sampurno, Sampurno; Andayani, Nurita; Laksmitawati, Dian Ratih
Jurnal Farmasi Indonesia Vol 11, No 2 (2019)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v11i2.670

Abstract

Top Brand Index data during 2012-2018 shows a stagnant and prone to declining growth percentage for certain immunomodulatory products. Toovercome this problem, producers tried to promote their products vigorously and to apply the right marketing strategy of the electronic word of mouth (e-WOM). Moreover, strengthening brand image on purchasing decision could be an alternative way to increase the market share of immunomodulatory producer companies. Hence, this study aimed (1) to determine the effect of e-WOM toward the decision to purchase immunomodulator products (research conducted in the DKI Jakarta area) as well as (2) the brand image to the same matter, then (3) to investigate further to what extent e-WOM as a marketing strategy influence the brand image of the marketed product. This study used a survey method and questionnaires has been distributed to 384 respondents in DKI Jakarta area. The obtained data were then analysed using Structural Equation Modeling (SEM)-PLS (Partial Least Square) by means of SmartPLS software. The results showed that (1) e-WOM affects significantly toward the decision to purchase immunomodulatory products and so does (2) the brand image. Then, (3) e-WOM proved to have a significant effect on the brand image of immunomodulatory products.
Co-Authors . Syamsudin Ahmad Faried Ana Yupita Liza Andayani, Nurita Andreas Infianto Ani Retno Prijanti Annisa Septyana Putri Ayu Werawati Bagus Bahtiar Bambang Ponco Priosoeryanto Cahyaning Riski Wijayanti Caroline Tan Sardjono CAROLINE TAN SARDJONO Chandra, Pra Panca Bayu Claudia Tiffani Dedy Kurniawan Deni Rahmat Deni Rahmat Devina Harti Syaputri Diah Kartika Pratami Diar Gustianti Istita Edwin Tomasoa Effionora Anwar Effionora Anwar Elisabeth Ninung Yuliarti Esti Mumpuni Esti Mumpuni Esti Mumpuni Esti Mumpuni, Esti Faradiba Faradiba Faridah Faridah Ferry Sandra Hanna Sari W Kusuma Hanna Sari Widya Kusuma HARI PURNOMO Hendig Winarno Hendig Winarno Hesti Utami Ramadaniati Hesti Utami Ramadaniati Hikariastri, Pangartika Indah Zahara Ivans Panduwiguna James Ibrahim Jayati, Turpuk Mannaria Jeanette Mangiwa Jeanne A. Pawitan Jeanne Adiwinata Pawitan Juliana Irem Adriana Purukan Katharina Aditya Candra Utukaman Kusmardi Kusmardi Kusmardi Kusmardi Laili Savitri Noor Laksono Trisnantoro Larasinta, Nadia Lia Warti Liliek Nurhidayati Magdalena Niken Oktovina Marwati, Umi Marybet Tri Retno Handayani Meilda Ayu Bathini Mita Restina Moch Futuchul Arifin Mohamad Sadikin Mohammad Sadikin Mokhamad mahroji Muhammad Hanafi Mulatsari, Esti Noor, Laili Savitri Novia Maulina Novia Maulina Nuraini Nuraini Nurita Andayani Okta, Fauzia Noprima Oriza Safrini Oriza Safrini Panca, Pra Panca Bayu Chandra Pangartika Hikariastri Partana, Citra Prastuti Partomuan Simanjuntak Patminingsih, Nanik Pra Panca Bayu Chandra Pra Panca Bayu Chandra Prasasta Sutedjo Prih Sarnianto Prih Sarnianto Prih Sarnianto Prilasari, Sharon Alia Rachmawati Noverina RAHMAT, DENI Rahmawati, Siti Irma Ramadaniati, Hesty Utami Ranald Irwanto Ratih Rinendyaputri Renni Septini Rikkit Sihombing Rilianawati Rilianawati Riska Eka Putri, Riska Eka Rizal Rizal Rizal Rizal Ronald Irwanto Ronald Irwanto Natadidjaja ROS SUMARNY Ros Sumarny Ros Sumarny Rudi Asmajaya Sahat Saragi Sampurno Sampurno Sampurno Sampurno Sarwono Waspadji Seila Arumwardana Selvy Devita Anggeraini Shelly Taurhesia Simbolon, Roslan Simbolon, Roslan Siti Umroh Noor Sutarno Syamsudin Abdillah Teulis Sumiartini Tomasoa, Edwin Trisna Lestari Umi Marwati Utukaman, Katharina Aditya Candra Vergie Indriani Wahono Sumaryono Wahyu Widowati Wahyu Widowati Wireni Ayuningtyas Yoppy Mayrosa Yudha Sukowati Yusi Anggraini Yusi Anggriani Yusi Anggriani Zahara, Indah