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All Journal Jurnal Ilmiah Farmasi The Journal of Experimental Life Sciences (JELS) Biotropika Pelita Perkebunan Folia Medica Indonesiana Jurnal Farmasi Klinik Indonesia Majalah Kulit, Karet, dan Plastik Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Pharmacon Journal of Tropical Biodiversity and Biotechnology INDONESIAN JOURNAL OF PHARMACY Pharmascience Journal of Islamic Pharmacy JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Sains dan Komunitas Journal of Islamic Medicine JSFK (Jurnal Sains Farmasi & Klinis) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Manuju : Malahayati Nursing Journal JFIOnline J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasi Higea Pharmacoscript An-Nadaa: Jurnal Kesehatan Masyarakat Pharma Xplore : Jurnal Sains dan Ilmu Farmasi ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Community Development Berkala Penelitian Hayati Pharmaceutical Sciences and Research (PSR) Agrimas : Jurnal Pengabdian Masyarakat Bidang Pertanian Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Suharjono, Suharjono
Faculty Of Pharmacy, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Updates Therapy for Covid-19 Patients in Pregnant and Lactating Women Review Journal Liziyyannida Liziyyannida; Suharjono Suharjono
Malahayati Nursing Journal Vol 5, No 6 (2023): Volume 5 Nomor 6 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v5i6.8883

Abstract

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes the coronavirus disease 2019 (Covid-19). On January 30, 2020 WHO declared Covid-19 a Public Health Emergency of international concern, and caused millions of deaths worldwide. COVID-19 infection can increase in patients who are pregnant. Changes in the immune system and physiology in pregnant women can increase the risk of complications from COVID-19 infection. Pregnancy can compromise the immune system and potentially SARS-CoV-2 infection can increase the risk of pneumonia in pregnant women compared to non-pregnant women. Pregnant women are often excluded from trials because of the risk of toxicity or side effects, resulting in a lack of knowledge about drug use and care during pregnancy. Great uncertainty in therapy due to lack of appropriate treatment information along with the increasing development of changes to the covid19 therapy guidelines. this review aims to gather existing knowledge on currently available drug treatments for COVID-19 in pregnant and lactating women, and produce an analysis of drugs with acceptable safety profiles in the treatment of pregnant and lactating women with COVID-19. This article series uses Mendeley, Google Scholar, ScienceDirect, and PubMed from the NCBI database during October - December 2022. Variables associated with the incidence of under-five malnutrition were maternal nutrition knowledge (p= 0,000; OR = 17,000), parenting and feeding patterns (p= 0,003; OR = 13,500), and family income (p= 0,002; OR = 12,000), while the availability of clean water (p= 0.449; OR = 2.429) was found unrelated with the incidence of under-five malnutrition. In conclusion, the availability of clean water is not related to the incidence of under-five malnutrition, while the other three variables studied are related. So, to prevent under-five malnutrition, it is necessary for mothers to take active action in seeking information on nutritious food, cultivating local food to increase family income and food supply and keep water clean. Further research needs to develop other variables that were not examined by researchers, namely food availability in the family and history of low birth weight babies. Researchers hope that mothers are active in seeking information about nutritious foods, utilizing existing local food to increase family income and food supply so that they are able to serve healthy nutritious food to families, especially toddlers. In addition, keep the water clean by treating drinking water properly so that it does not become a source of spreading disease Keywords: Toddlers, Malnutrition, Income, Knowledge of Nutrition, Parenting  ABSTRAK Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) merupakan     virus yang berperan atas penyakit coronavirus 2019 (Covid-19). Pada tanggal 30 Januari 2020 WHO menetapkan Covid-19 sebagai Public Health Emergency yang menjadi perhatian Internasional, dan menyebabkan jutaan kematian di seluruh dunia. Infeksi COVID-19 dapat meningkat pada pasien dengan kondisi hamil. Perubahan sistem imun dan fisiologi pada wanita hamil dapat meningkatkan risiko komplikasi infeksi COVID-19. Kehamilan dapat membahayakan sistem kekebalan tubuh dan berpotensi infeksi SARS-CoV-2 dapat meningkatkan risiko pneumonia pada wanita hamil dibandingkan dengan wanita yang tidak hamil. Wanita hamil sering dikeluarkan dari uji coba karena terdapat risiko toksisitas atau efek samping, yang mengakibatkan kurangnya pengetahuan tentang penggunaan obat dan perawatan selama kehamilan. Ketidakpastian terapi yang besar karena kurangnya informasi pengobatan yang tepat seiring dengan meningkatknya perkembangan perubahan pedoman terapi  covid19. Kajian ini bertujuan untuk mengumpulkan pengetahuan yang ada tentang perawatan obat yang tersedia saat ini untuk COVID-19 pada wanita hamil dan menyusui, dan menghasilkan analisis obat-obatan dengan profil keamanan yang dapat diterima dalam pengobatan wanita hamil dan menyusui dengan COVID-19. Suran artikel ini menggunakan Mendeley, Google Scholar, ScienceDirect, dan PubMed dari database NCBI selama Oktober - Desember 2022. A search for this article using Mendeley, Google Scholar, ScienceDirect, and PubMed from the NCBI database during October - December 2022 Administration of drugs to pregnant and nursing patients who are exposed to COVID-19 must be seriously considered. Some therapies are not recommended because they can harm the fetus. Safe therapy given to pregnant and lactating patients who are exposed to COVID 19, namely vitamin c, vitamin d, paracetamol, nac, azithromycin, ramdesivir, dexamethasone, enoxaparine, UFH, and vaccines require special attention and close monitoring. Every pregnant woman has the right to have a safe and positive birth experience, including if they are confirmed to have contracted COVID 19 or not. Pregnant women are more susceptible to a number of infectious diseases, including Covid-19. Pregnant women infected with Covid-19 are more at risk of experiencing high levels of severity, requiring ventilators or intensive care. In addition, pregnant women are more susceptible to Covid-19 infection because their pregnancy puts the body in a state of immunosuppression. Immunosuppression is a state of reduced capacity of the immune system. So that the risk of complications increases such as pre-eclampsia, coagulopathy, preterm labor (increased premature birth), miscarriage (neonatal mortality) to death. Given the importance of reducing the risk of COVID-19 for pregnant and lactating women and their neonates, it is important to determine the safety profile of all drugs in real time. So that it can provide accurate data expectations according to the expectations of all pregnant and lactating women in the world. The following types of treatments are presented as safe during pregnancy and lactation, without teratogenic effects and minimal exposure to breastfed infants, namely Azithromycin, Ramdesivir, Dexamethasone, Enoxaparine, and UFH require special attention and close monitoring. As well as additional therapy according to symptoms that arise in pregnant and lactating female patients with COVID-19, namely Vitamin C, Vitamin D, Paracetamol, and NAC. Regarding vaccination, it is strongly recommended that all pregnant women in their second and third trimesters receive the COVID-19 vaccine. The administration of the first dose of vaccination begins in the second trimester of pregnancy and the administration of the second dose is carried out according to the interval of the type of vaccine. The COVID-19 vaccine (either mRNA or viral vector) does not contain replicating virus, so it is highly recommended for pregnant and lactating women with a high risk of exposure. coronavirus continues to undergo COVID-19 vaccination. Keywords: SARS-CoV-2, COVID-19, Pregnant Women, Lactating Woman, Pharmacological Treatment 
UJI STABILITAS SEDIAAN AMPISILLIN SULBAKTAM SETELAH REKONSTITUSI I Gede Edy Sagitha; Suharjono Suharjono; Yulistiani Yulistiani; Isnaeni Isnaeni
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 8 No 1 (2023): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v8i1.4333

Abstract

Repeated use of antibiotic ampicillin sulbactam after reconstitution, therefore in storage various many factor can affect it stability such as type of solvent used, storage temperature and storage time. Objective of study is to analyze the chemical stability product of ampicillin sulbactam in repeated use with the parameters of the solvent and storage temperature Sample products were weighed and reconstituted using WFI and NS solvents, diluted ad 20 ppm and put into sterile vials. Then stored at room temperature (25-30 ° C) and refrigerator temperature (4-8 ° C). Storage is carried out for 24 hours which is divided into 4 -time series, namely 0, 1, 4 and 24 hours. Each time series is microbiological tested and after 18 hours incubation the inhibition zone is observed and its diameter measured using calipers. Result of study is at 0th hour showed a significant difference in different solvents. Samples dissolved with NS solvents have a greater inhibition zone than those dissolved using WFI. This happens because there is a primary salt effect that occurs with the influence of electrolytes (salt) or variations in the strength of ions can affect the coefficient of activity that affects the reaction rate. From the statistical analysis at the 1st and 4th hours, the storage temperature that provides significant result, storage in the refrigerator produces better results compared to storage at room temperature. At 24 hours the temperature and solvent did not give the significant result on the stability of the sulbactam ampicillin sample. Conclusion is NS solvents give better results than WFI solvents. Samples are more stable if stored in a refrigerator. After 4 hours based on the above study the sample no longer meets the requirements of Indonesian Pharmacopoeia 5th edition
Peran Fomepizole dalam Penanganan Toksisitas Etilen Glikol dan Dietilen Glikol Lewi Tigor Simorangkir; Suharjono Suharjono
Journal of Islamic Pharmacy Vol 8, No 1 (2023): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v8i1.20790

Abstract

Etilen glikol dan Dietilen glikol merupakan alkohol yang bersifat toksik yang dapat meningkatkan mortalitas dan morbiditas. Pada tahun 1997 FDA menyetujui penggunaan fomepizole (4-methylpyrazole) sebagai tatalaksana toksisitas etilen glikol yang dapat di kombinasi dengan terapi hemodialisa. Fomepizole adalah inhibitor kompetitif alcohol dehydrogenase sama seperti etanol sehingga dapat menghambat pembentukan metabolit toksik dari etilen glikol. Fomepizole memiliki afinitas 8.000 kali lebih besar terhadap alcohol dehydrogenase dibandingkan etanol serta  farmakokinetik fomepizole dapat di prediksi dan efek samping lebih ringan. Pedoman saat ini dari beberapa literatur menyarankan terapi hemodialisa pada toksisitas etilen glikol jika konsentrasi serum etilen glikol dalam darah 50 mg/dL, asidosis berat, gagal ginjal, dan kadar asam glikolat 10 mmol/L. Sedangkan fomepizole dapat indikasikan jika konsentrasi plasma Etilen Glikol 20 mg/dL, riwayat penggunaan penggunaan etilen glikol dan dietilen glikol dengan osmolal GAP 10 mOsm/L atau kecurigaan penggunaan etilen glikol dan dietilen glikol dengan PH arteri 7,3, CO2 20 mmol/L dan osmolar GAP 10 mOsm/L 
Peran Fomepizole dalam Penanganan Toksisitas Etilen Glikol dan Dietilen Glikol Simorangkir, Lewi Tigor; Suharjono, Suharjono
Journal of Islamic Pharmacy Vol 8, No 1 (2023): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v8i1.20790

Abstract

Etilen glikol dan Dietilen glikol merupakan alkohol yang bersifat toksik yang dapat meningkatkan mortalitas dan morbiditas. Pada tahun 1997 FDA menyetujui penggunaan fomepizole (4-methylpyrazole) sebagai tatalaksana toksisitas etilen glikol yang dapat di kombinasi dengan terapi hemodialisa. Fomepizole adalah inhibitor kompetitif alcohol dehydrogenase sama seperti etanol sehingga dapat menghambat pembentukan metabolit toksik dari etilen glikol. Fomepizole memiliki afinitas 8.000 kali lebih besar terhadap alcohol dehydrogenase dibandingkan etanol serta  farmakokinetik fomepizole dapat di prediksi dan efek samping lebih ringan. Pedoman saat ini dari beberapa literatur menyarankan terapi hemodialisa pada toksisitas etilen glikol jika konsentrasi serum etilen glikol dalam darah 50 mg/dL, asidosis berat, gagal ginjal, dan kadar asam glikolat 10 mmol/L. Sedangkan fomepizole dapat indikasikan jika konsentrasi plasma Etilen Glikol 20 mg/dL, riwayat penggunaan penggunaan etilen glikol dan dietilen glikol dengan osmolal GAP 10 mOsm/L atau kecurigaan penggunaan etilen glikol dan dietilen glikol dengan PH arteri 7,3, CO2 20 mmol/L dan osmolar GAP 10 mOsm/L 
Pemanfaatan Keong Mas Untuk Pupuk Organik Cair di Kelompok Tani Podo Tentrem Kecamatan Wuluhan Jember Suharjono, Suharjono; Asmono, Sepdian Luri; Wardana, Rudi
Journal of Community Development Vol. 3 No. 3 (2023): April
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/comdev.v3i3.108

Abstract

The golden snail is one of the pests that damage rice plants, this pest has the ability to reproduce quickly, causing the golden snail to become one of the main pests in lowland rice. But the golden snail can be used as a basic material for liquid organic fertilizer (LOF) because it contains protein, Azotobacter, Azospirillum, phosphate solubilizing microbes, Pseudomonas, Staphylococcus, enzymes and the hormone auxin. The effectiveness of the golden snail LOF has been tested on several agricultural crops, one of which is rice. In the Podo Tentrem Farmers Group, these pests are simply thrown away and have not been utilized properly. Whereas the potential of this golden snail can be very high if it is processed into organic fertilizer. Therefore, with this community service activity, it is hoped that it can improve competence, skills and increase the production output of the Podo Tentrem farmer group. This can be measured by the enthusiasm of the participants who were attended by 100% of the invitees, besides that the participants also knew the stages of work and succeeded in making Keong Mas LOF well. In addition, other assessment indicators are using quantitative data on pre-test and post-test scores. Before the counseling was carried out, the pretest value was 50 and after the knowledge training, it increased with an average post-test score of 76. These results can indicate that in theory and practice, on average, participants understand and can make golden snail LOF.
REVIEW ARTIKEL: EFIKASI, KEAMANAN, DAN DURASI PENGGUNAAN ANTIPLATELET GOLONGAN P2Y12 INHIBITOR PADA PASIEN SINDROM KORONER AKUT Yustiana, Yustiana; Suharjono, Suharjono; Dwiyatna, Surya; Atmajani, Wanudya
Jurnal Farmasi Higea Vol 16, No 1 (2024)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v16i1.590

Abstract

Sindroma koroner akut (SKA), termasuk unstable angina (UA) dan infark miokard (IM) merupakan manifestasi penyakit jantung koroner. Penyakit jantung koroner merupakan penyebab kematian terbesar pada kasus kardiovaskular sehingga diperlukan penanganan dan terapi yang adekuat. Terapi antiplatelet merupakan terapi utama dalam manajemen penanganan sindroma koroner akut. Dual antiplatelet therapy (DAPT) adalah standar terapi da SKA. Antiplatelet golongan P2Y12 inhibitor merupakan salah satu komponen penting dalam DAPT. Adanya risiko perdarahan dan kejadian iskemia yang dapat terjadi selama terapi dengan P2Y12 inhibitor membuat pemilihan P2Y12 inhibitor menjadi suatu yang krusial. Pemilihan jenis obat dan durasi antiplatelet P2Y12 inhibitor tidak hanya mempertimbangkan efikasi, seperti MACE, tetapi juga perlu mempertimbangkan keamanan pasien, seperti kejadian, major bleeding, dan kejadian iskemia. Review artikel ini akan membahas terkait efikasi, keamanan, serta durasi dari penggunaan P2Y12 inhibitor pada pasien SKA berdasarkan bukti-bukti klinis.
Analisis Penggunaan Antibiotik Pada Pasien Bedah Umum dengan Metode ATC/DDD di RSAU Efram Harsana Lanud Iswahyudi Maospati Sahayuna, Dara Demi; Sindy, Sulih Probo; Solihin, Imron; Suharjono, Suharjono
Jurnal Pharmascience Vol 11, No 1 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i1.8914

Abstract

Penggunaan antimikoba pada pasien bedah umum pasca operasi digunakan untuk mencegah terjadinya infeksi luka operasi. Namun pada penggunaan antimikroba yang tidak bijak dapat menyebabkan terjadinya resistensi antibiotik. Jika sudah terjadi resistensi antibiotik hal tersebut dapat menyulitkan terapi. Oleh karena itu, perlu dilakukannya pengendalian penggunaan antibiotik dengan cara penggunaan yang rasional / bijak. Pencegahan terjadinya resistensi antimikroba dapat dilakukan dengan menyesuaikan pemberian antibiotik pada pedoman terapi serta dapat dilakukan evaluasi secara kuantitatif maupun kualitatif secara berkala. Tujuan penelitian ini adalah untuk mengetahui nilai DDD dari antibiotik di RSAU Efram Harsana Lanud Iswahyudi. Penelitian ini merupakan penelitian deskriptif-analitik dengan desain cross sectional dengan pengambilan data secara retrospektif pada pasien bedah umum RSAU Efram Harsana Iswahjudi selama peridoe Juli-September 2019. Dari laporan rekam medis peresepan antibiotik sebanyak 401 dari 339 rekam medis diperoleh hasil dengan pemakaian jenis antimikroba tertinggi  golongan sefalosporin ceftriaxon 15,909/100 pasien-hari dan pemakaian jenis antimikroba terendah yaitu ceftazidim 0,098/100 pasien-hari.  Kata Kunci: Pasien Bedah Umum, Antibiotik, ATC/DDD, Resistensi Antimikroba, DDD/100. The use of antimicrobials in postoperative general surgery patients is used to prevent wound infection. However, the use of antimicrobials that are not wise can cause antibiotic resistance. If antibiotic resistance has occurred this can complicate therapy. Therefore, it is necessary to control the use of antibiotics by means of rational use. Prevention of antimicrobial resistance can be done by adjusting the administration of antibiotics in the therapeutic guidelines and periodic quantitative and qualitative evaluations can be done. This study aims to determine the DDD value of antibiotics in general surgery patients at Efram Harsana Hospital Iswahjudi Lanud. This research is a type of descriptive study with a retrospective cross sectional design using ATC / DDD analysis. Data obtained from the medical records of general inpatients in Efram Harsana Hospital peridoe July-September 2019. From the medical record report prescribing antibiotics as many as 401 out of 339 medical records obtained results with the use of the highest type of antimicrobial cephalosporin ceftriaxon 15,909 DDD / 100 days of treatment and 100 days of treatment and obtained the results of the use of the highest antimicrobial type cephalosporin ceftriaxon 15,909 DDD / 100 days of hospitalization and The lowest use of antimicrobial types was ceftazidim 0.098 DDD / 100 days of hospitalization.
Comparison of Soil Arthropod Diversity and Community Structure in Various Types of Land Cover in Malang Region, East Java, Indonesia Yanuwiadi, Bagyo; Suharjono, Suharjono; Kurniawan, Nia; Fathoni, Muhammad; Nurrofik, Agus; Assiddiqy, Miftah Farid; Shahroni, Abdul Mutholib
Journal of Tropical Biodiversity and Biotechnology Vol 8, No 3 (2023): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jtbb.79496

Abstract

Land cover heterogeneity can affect the structure of biodiversity in the supplied niche, so it is necessary to know the taxa community. This study aimed to understand the effect of land cover variation on the diversity and community structure of soil arthropods. The types of habitats used include urban areas, agroforestry, gardens, and natural forests which are determined in the Malang Region, East Java, Indonesia. Hand sorting and hay bait traps were applied in this study to obtain a variety of arthropod soils and the Berlese-Tullgren funnel was used to extract them. As a result, there are 25 families from 15 orders collected based on their ecological roles. The abundance of Philoscidae in sites S1 and S2 (urban green space), Talitridae in site S6 (agroforestry), and Isotomidae in sites S3, S4, and S5 (highland mixed forest) was highest and dominant. Site S7 has the highest diversity (H' = 2.56; 1-D = 0.90; J' = 0.76) even though its family richness is lower. The site S3 counter-site had relatively high taxa richness (TR = 13), but low diversity (H' = 1.02; 1-D = 0.39; J' = 0.16). Based on clustering analysis and NMDS ordination, 3 classifications of habitat types were obtained, namely I (S6 & S7), II (S3, S4 & S5), and III (S1 & S2). Mixed forest habitats contain a more complex diversity of soil arthropods, which can serve as a model for improving the fertility of disturbed ecosystems. 
Profil Pengetahuan Penyakit Kanker Dan Dampak Bahan Berbahaya Di Lingkungan Masyarakat Pengrajin Sandal Mahardian R, Mahardian R; Ratri, Dinda Monika Nusantara; Yusfar, Yunarti; Samirah, Samirah; Chrismawan A, Chrismawan A; Suharjono, Suharjono
An-Nadaa: Jurnal Kesehatan Masyarakat (e-Journal) Vol 10, No 2 (2023): AN-NADAA JURNAL KESEHATAN MASYARAKAT (DESEMBER)
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/ann.v10i2.9801

Abstract

Penelitian ini menunjukkan pemahaman dan sikap peserta sudah baik mengenai penyakit kanker, pencegahan kanker dan dampak cemaran bahan berbahaya yang mempengaruhi kesehatan. Namun, masih terdapat masyarakat yang menunjukkan  dari peserta perlu meningkatkan pengetahuan mereka tentang pola hidup sehat, pola hidup sehat untuk mencegah kanker dan dampak cemaran serta bahan – bahan yang mencemari lingkungan
Peran Vitamin D Terhadap Kanker: Sebuah Tinjauan Literatur Umami, Zahra; Suharjono, Suharjono
Journal of Islamic Medicine Vol 8, No 2 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i2.26058

Abstract

Vitamin D is a potent steroid hormone precursor that regulates a broad spectrum of physiological processes in the body. Besides its general role in bone metabolism, vitamin D plays an important role in the prevention and treatment of many diseases such as cancer. The aim of this literature review is to examine in more depth the role of vitamin D as an anticancer. There are studies that reveal biological mechanisms mediated by vitamin D in regulating cancer cells, such as cell renewal, cell proliferation, cell differentiation, cell transformation, and cell death. Other studies have also revealed a link between the immune system and the anti-neoplastic effects of vitamin D. Research shows that low levels of vitamin D in circulation are associated with an increased risk of cancer. The use of supplementation alone or in combination with immunotherapy or other chemotherapy may promote better clinical outcomes. These promising results still require further development and research through novel approaches targeting vitamin D signaling and metabolic systems to improve cancer therapeutic outcomes.
Co-Authors A.A. Ketut Agung Cahyawan W Achmad Ridwan Achmad Ridwan, Achmad Agriawan Sudirman Ahmad Nasir ahmad, abraham Andri Geger Noviantoro Aprillia Wijaya, Stefani Ari Wibowo Arief Bachtiar Arina Dery Puspitasari Assiddiqy, Miftah Farid Atmajani, Wanudya Bagiyo, Harry Bagiyo, Harry Bagyo Yanuwiadi Bambang Eko Wahyono Bambang Sidharta Bambang Sudarmanto Budi Suprapti Budiatin, Aniek Setya Budiatin, Aniek Setya Chairunnisa Chairunnisa Chris Alderman Chrismawan A, Chrismawan A Chrismawan Ardianto Dea Ayu Nabilah Debora Shinta Liana Desiani, Ekanita Dewi Wara Shinta Didik Hasmono Dinda Monika Nusantara Ratri Diniah, Melisa Nur Djafar, Zaenab Dwiyatna, Surya Elvan Dwi Widyadi Emiliana Kasmudjiastuti Emy Sulistyo Astuti Endang Retnowati Eni Susanti Faizal Mustamin Fandyka Yufriza Ali Fasich Fasich Fransiska Maria Christianty Gratia, Veronica Hari Prasetyo Hasria Alang Heru Purwanto Hubby, Hubby I Gede Edy Sagitha I Ketut Mandikin Ilham Rizqy Isnain Imam Faozi Imam Susilo Indira D. Kharismawati Irfan Mustafa Irma Novrianti Irma Novrianti Irvina Harini Isnaeni Jaka Susila Jikrona, Rafi Joni Kusnadi Joni Wahyuhadi, Joni Jufri Ubrusun Junaidi Khotib Kenyo Alexandra Oktaviani Khaerani Khaerani Khusnul Fitri Hamidah Kusuma Arum Ningsih Kuwatno Kuwatno Lestiono, . Lestiono, . Lewi Tigor Simorangkir Lisa Narulita Lisa Narulita Liziyyannida Liziyyannida M. Yusuf Assegaf Mahardian R, Mahardian R Mahardian Rahmadi Mahfudz Mahfudz Makitalentu, Feybe Marcha Debby Saraswati Mareta Rindang Andarsari Medina, Farah Meita Rafika Fitriani Mohammad Akram Muhammad Aminuddin, Muhammad Muhammad Fathoni, Muhammad Mulja Hadi Santosa Narulita, Lisa Nasir, Ahmad Neldi, Vina Nia Kurniawan Nur Afni NUR CHAKIM Nurmainah Nurmainah Nurrofik, Agus Paulus Sugianto Prasetyanti, Intan Kris Prastuti Asta Wulaningrum Pratita, Dian Galuh Primadi Avianto Purwanto, Diyna Rusayliya Rahman, Gilang Mauladi Rahmawati Raising Ria Rositasati Riefkah Bilal risha fillah fithria Risthanti, Reine Risa Rosdiana, Eva Rudi Safarudin Rudi Wardana Rusdiana, Silvia Rusdiana, Silvia Safarudin, Rudi Sahayuna, Dara Demi Samirah Samirah Samirah Samirah, Samirah Sari, Erni A Semedi S J Shafira Muti Ardiana Shahroni, Abdul Mutholib Shofia Ummu, Lathifa Simorangkir, Lewi Tigor Sindy, Sulih Probo SJ, Semedi Solihin, Imron Sudirman, Agriawan Sukardiman Sumarno . Sumarno Sumarno Suryadi Suryadi Susilo, Dwi Hari Sutrisnaningsih, Evy Sari Suwardi Suwardi Toetik Aryani Tri Ardyati Umami, Zahra Veronica Gratia WENNY PUTRI NILAMSARI Widhiati Widhiati Widyadi, Elvan Dwi Wiwid Samsulhadi Wulan Panduwi Melasari Yance Anas yance yance Yen Yen Ari Indrawijaya YOGA DWI JATMIKO Yogiarto Yogiarto Yulia Ayu Purnamasari Yulistiani Yulistiani Yulistiani Yulistiani, Yulistiani Yulistiani, . Yuniati T Yuniati T Yuniati T, Yuniati Yusfar, Yunarti Yustiana Yustiana, Yustiana Zamrotul Izzah Zulfiana, Risa