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All Journal Jurnal Kedokteran Brawijaya Majalah Kedokteran Bandung Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Kesehatan Reproduksi Journal of Auditing, Finance, and Forensic Accounting Jurnal Riset Gizi Majalah Obstetri dan Ginekologi Nusantara Medical Science Journal Universa Medicina Indonesian Journal of Obstetrics & Gynecology Science Jurnal Kesehatan Reproduksi Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Indonesian Journal of Medicine Journal of Maternal and Child Health JURNAL PENDIDIKAN TAMBUSAI Jurnal Manajemen dan Administrasi Rumah Sakit Indonesia (MARSI) Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Nusantara Science and Technology Proceedings Jurnal Ilmiah Raflesia Akuntansi Indonesian Journal of Perinatology JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Innovative: Journal Of Social Science Research Jurnal Ilmiah Sultan Agung Jurnal Akuntansi, Keuangan dan Perpajakan Legalpreneur Journal Jurnal Dwija Kusuma Jurnal Riset Gizi Jurnal Riset Gizi Proceeding Mulawarman International Conference on Tropical Public Health Jurnal Pendidikan Guru Profesional Jurnal Kesehatan Masyarakat Folia Medica Indonesiana
Sri Sulistyowati
Department Of Obstetric And Gynecology, Faculty Of Medicine, Sebelas Maret University
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THE DIFFERENCE HUMAN LEUKOCYTE ANTIGEN-E (HLA-E) EXPRESSION AND NATURAL KILLER CELLS (NK CELLS) IN TROPHOBLAST BETWEEN INTRAUTERINE GROWTH RESTRICTION (IUGR) AND NORMAL PREGNANCY soetrisno soetrisno; Sri Sulistyowati; Supriyadi Hari Respati; Bambang Triono Cahyadi
Nusantara Medical Science Journal Volume 3 No. 1 Januari - Juni 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i1.5781

Abstract

Background: Intrauterine growth restriction (IUGR) is still a major cause of perinatal morbidity and mortality. IUGR incidence ranged from 4.4 to 6.44% of pregnant women. Human Leukocyte Antigen - E and NK cells are thought to play an important role towards the process of IUGR.Objective: To determine aetiopathogenesis HLA-E expression and NK Cell in IUGR.Methods: An analytical observational study conducted through a cross-sectional approach. The research was conducted on March-October 2015 at the Obstetrics and Gynecology Department, Dr. Moewardi Hospital Surakarta and at of Laboratory of Pathology, Faculty of Medicine, Universitas Sebelas Maret Surakarta. Subjects who meet the inclusion and exclusion criteria consisted of 20 patients with IUGR and 20 normal pregnant patient. The researcher examined HLA-E Expression and NK cells in trophoblast using immunohistochemical method and statistical analysis using t test.Results: The average HLA-E expression in the trophoblast in IUGR group 17.80 ± 5.55, compared with normal pregnancy 66.23 ± 19.83, p value = 0.0001 (p <0.05). The average expression of NK cells in trophoblast in IUGR group 137.71 ± 28.09 compared with normal pregnancy 31.75 ± 14.77, p value = 0.0001 (p <0.05).Conclusion: HLA-E expression in normal pregnancy trophoblast is higher than pregnancies with IUGR. Expression of NK cells in pregnancy with IUGR is higher compared with normal pregnancy.
Pengaruh Psikokuratif terhadap Kadar VEGF-c, Kortisol dan Skor HADS Pasien Kanker Serviks Stadium Lanjut Soetrisno Soetrisno; Sri Sulistyowati; Rubin Enhui Tjiang; Hari Wujoso; Hafi Nurinasari; Erindra Budi Cahyanto
JURNAL KESEHATAN REPRODUKSI Vol 7, No 1 (2020)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.468 KB) | DOI: 10.22146/jkr.50642

Abstract

Background: Cancer diagnosis and therapy that causes chronic stress, its progression to depression  increase cortisol and VEGF-c levels in advanced cervical cancer patientsObjective: To  know the VEGF-c, cortisol and HADS level  in advanced stage cervical cancer patients who get Psychocurative intervention Method : An experimental study of pretest – posttest controle group design in outpatient oncology clinic and ward of Doctor Moewardi General Hospital. Thirty subjects with advanced cervical cancer were randomly divided into 15 patients in the intervention group, and 15 in control. Psycho-curative intervention 4 times a month, 1 time a week, 60 minutes duration. Before and after intervention, each subject of the two groups was examined levels of VEGF-c, cortisol and HADS scores. Data obtained were analyzed by independent t test, Mann Whitney, Pair t and Wilcoxon with the 19th version of SPSS for Windows.Result and Discussion: Average VEGF-c levels before intervention 9006.53 ± 2181.49, after intervention 5631.20 ± 2071.55, p <0.001. The mean cortisol level before intervention was 12.29 ± 4.36, after intervention 6.71 ± 3.88, p <0.001. The mean HADS Anxiety score before intervention was 14.13 ± 3.02, after intervention 8.47 ± 3.07, p <0.001. Mean Depression HADS scores before intervention 13.80 ± 3.21, after intervention 7.20 ± 2.70, p <0.001.Conclusion : VEGF-c levels, cortisol, HADS anxiety scores and depression in patients with advanced cervical cancer decline after psychocurative intervention. Keywords : Psychocurative; VEGF-c; Cortisol; HADS; Cervical cancer
Apakah Endometriosis Mempengaruhi Kualitas Embryo pada Pasien Invitro Fertilization? Dewanto Suryoningrat; Abdurahman Laqif; Soetrisno Soetrisno; Uki Retno Budihastuti; Sri Sulistyowati
JURNAL KESEHATAN REPRODUKSI Vol 8, No 1 (2021)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.63039

Abstract

Latar Belakang Invitro Fertilization merupakan salah satu manajemen infertilitas yang baik, namun masih didapatkan adanya kesamaan peluang kegagalan perkembangan embrio sebanyak 50% dibandingkan dengan pasien yang tidak mengalami endometriosis.Tujuan: untuk mengetahui hubungan endometriosis dan kualitas embrio pada pasien yang menjalani program invitro fertilization.Metode: Data yang dikumpulkan merupakan data pada rekam medis pasien Klinik Fertilitas Sekar yang menjalani invitro fertilization di Klinik Fertilitas Sekar RSUD Dr. Moewardi Surakarta pada Januari 2010 – Desember 2019. Analisis menggunakan uji deskriptif dan Uji T tidak berpasangan. Hasil dianggap signifikan jika p ≤ 0,05.Hasil dan Pembahasan: Dalam penelitian ini, rerata kualitas embrio baik memiliki perbedaan yang signifikan (p<0.05) antara pasien dengan endometriosis dan pasien tanpa endometriosi, sedangkan kualitas embrio buruk tidak memiliki perbedaan yang signifikan (p>0.05).Kesimpulan: Endometriosis memiliki hubungan yang signifikan dengan kualitas embrio pada wanita yang menjalani program IVF.
Difference of Serum MMP9 and TNF 􀁃 Level in Preterm and Term Premature Rupture of Membranes Aji P Wibowo; Sri Sulistyowati; Supriyadi H Respati
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.246 KB) | DOI: 10.32771/inajog.v3i1.20

Abstract

Objective: To examine the difference between matrix metalloproteinase‐ 9 (MMP‐9) and Tumor Necrosis Factor 􀁃 (TNF‐􀁃) serum levels in preterm and term premature rupture of membranes (PROM). Method: Our study employed an observational cross sectional approach. Seventy samples were divided into two groups, 35 samples with preterm PROM (28‐36 weeks gestational age) and 35 samples with PROM at term pregnancy (37‐42 weeks gestational age). Both groups underwent examination for serum MMP‐9 and TNF‐􀁃 concentration using ELISA method. Statistical analysis was done using ttest. Result: Serum levels of MMP‐9 in the preterm PROM group was 2860.68K627.32 ng/ml, which was significantly higher than in the PROM at term pregnancy group 2549.74K657.15 ng/ml (p=0.04). Likewise, the average serum level of TNF‐􀁃 in subjects with preterm PROM was 12,086.60K5384.51 ng/ml, significantly higher in comparison to PROM at term pregnancy, which was 6422.51K2645.32 ng/ml (p=0.00). Conclusion: Serum levels of MMP‐9 and TNF‐􀁃 in preterm PROM is significantly higher than that in PROM at term pregnancy. Keywords: MMP‐9, premature rupture of membranes, preterm, term, TNF‐􀁃
Low Class Ib (HLA-G/Qa-2) MHC Protein Expression against Hsp-70 and VCAM-1 Profile on Preeclampsia. An observation on experimental animal Mus Musculus with Endothelial Dysfunction model Sri Sulistyowati
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 3, July 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (162.572 KB)

Abstract

Objective: To analyze the expression of MHC class Ib Qa-2 protein (homologue to HLA-G in human), Hsp-70, and VCAM-1 in trophoblast cells of preeclampsia and control using endothelial dysfunction model on Mus Musculus. Method: Design of study is experimental study. Pregnant mice was treated with anti-Qa-2. Hsp-70 and VCAM-1 expressions of trophoblast cells was assessed on week I, II, and III. Result: Negative Qa-2 expression was achieved after administration of 40ng anti Qa-2 on the fifth day of pregnancy. The Hsp-70 and VCAM-1 expressions in negative Qa-2 mice (preeclampsia) was higher compared with those of positive Qa-2 mice (normal pregnancy) on week I, II and III. Conclusion: Low Qa-2 and high of HSP-70 and VCAM-1 expression might be useful for prediction of preeclampsia or endothelial dysfunction. [Indones J Obstet Gynecol 2010; 34-3: 103-7] Keywords: preeclampsia, HLA-G/Qa-2, Hsp-70, VCAM-1, endothelial dysfunction
The Influence of Low HLA-G Protein Expression on Hsp-70 and VCAM-1 Profile in Preeclampsia Sri Sulistyowati
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 4, October 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (731.532 KB)

Abstract

Objective: To analyze HLA-G, Hsp-70, and VCAM-1 proteins expression on trophoblast in women with preeclampsia and women with normal pregnancy, and to assess causality relationship between low HLA-G expression and the increased Hsp-70 and VCAM-1 expression in preeclampsia. Method: Observational analytic study with cross sectional design. Results: Trophoblastic HLA-G expression in pregnant women with preeclampsia is lower (p = 0.01) than its expression in women with normal pregnancy. The expressions of Hsp-70 (p = 0.02) and VCAM-1 (p = 0.00) in preeclampsia are higher, compared to normal pregnancy. Regression analysis showed that low HLA-G is a predictor for the increase of trophoblastic Hsp-70 and VCAM-1. Conclusion: Low trophoblastic HLA-G in is a predictor for endothelial dysfunction in women with preeclampsia. [Indones J Obstet Gynecol 2010; 34-4: 185-90] Keywords: preeclampsia, HLA-G, Hsp-70, VCAM-1, endothelial dysfunction
Skin manifestations of COVID-19 in a pregnant woman with premature rupture of membranes: A case report Sri Sulistyowati; Nutria Widya Purna Anggraini
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 1, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss1.art14

Abstract

The number of COVID-19 cases, especially with pregnancy, remains a problem in the world and in Indonesia. The main clinical symptoms include fever (temperature >38°C), cough, and shortness of breath. In addition, it can be accompanied by fatigue, myalgia, gastrointestinal symptoms such as diarrhea, and even recently found manifestations of skin disorders. Skin manifestations in COVID-19 pregnant patients are still a rare condition. Skin manifestations can be an early sign of such infection, which therefore requires clinicians’ notice to allow them to conduct early COVID-19 screening in pregnant women for better outcomes of the mother and the baby. We present a 26-year-old primigravida at 39 weeks of gestational age with premature rupture of membranes and COVID-19 infection. Her complaints included itchy maculopapular rash and urticaria, then the pregnancy was terminated by a caesarean section, and the baby was born with good conditions. The skin lesions were given a mixture of corticosteroid cream and fusidic acid. The mother and the baby were discharged in a good condition.
THE EFFECT OF ABO BLOOD GROUP ON COVID-19 IN PREGNANCY Sri Sulistyowati; Nutria Widya Purna Anggraini; Soetrisno Soetrisno; Eric Edwin Yuliantara; Supriyadi Hari Respati; Muhammad Adrianes Bachnas; Wisnu Prabowo; Hafi Nurinasari; Dympna Pramelita; Dewi Setiyawati; Metharisa Sujana; Aldi Firmansyah
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art6

Abstract

Background: The COVID-19 virus has spread throughout the world and has been declared as a global pandemic by WHO. Some population groups are more susceptible to COVID-19, and one of them is pregnant women. Pregnancy increases risks of the COVID-19, especially thrombotic complications. The SARS-CoV-2 infection may vary widely from asymptomatic to severe infection. Some studies have shown that ABO blood group can be a marker of susceptibility to some disease progression. Objective:This study aims to investigate relationships between the ABO blood group, the COVID-19 infection and its complications in pregnant women at Dr. Moewardi Hospital, Surakarta.Methods: This study was an observational analytic study with a cross-sectional study design involving 40 pregnant women infected with COVID-19 at Dr. Moewardi Hospital, Surakarta. COVID-19 PCR swabs on the women were administered on their oropharynx and nasopharynx, and laboratory examination of the ABO blood group in all samples was performed. Comparative data distribution of blood groups in the population and the global population distribution were calculated by Chi Square Goodness of Fit. Comparative data between ABO blood group distributions, blood parameters and complications (respiratory, thrombotic, other infections, and death) were calculated by Chi square test and then by One-Way ANOVA. Next, correlation tests for the complications of the blood group and the ages applied a multinomial regression.Results: There were significant differences of thrombotic complications on the blood group of pregnant women infected with COVID-19 (p=0.027). Blood type B significantly tended to experience thrombotic complications when compared to other blood groups (p=0.022).Conclusion: The ABO blood group could affect the complication levels in the pregnant women infected with the COVID 19.
The Benefits of Smartphone-Based Health Applications in Increasing Knowledge About Preconception Care: A Research and Development Study Firda Fibrila; Sri Sulistyowati; Muhammad Akhyar; Anik Lestari
Nusantara Science and Technology Proceedings Multi-Conference Proceeding Series C
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2601

Abstract

Background: Knowledge influences the use of preconception care. The purpose of developing the application in this study is to obtain health promotion media that can increase knowledge and attitudes about preconception care. Methods: A development study using the Four-D model was carried out in Metro Indonesia from November 2021 to January 2022. Using an experimental design with 60 young women selected in a limited-scale trial. Divided into two groups randomly, where the treatment group has access to utilize information media in the application. Data obtained from pre-test and post-test. Furthermore, the analysis was carried out using the SPSS software version 25.0 using an independent t-test. Result: Application adoption reached 96.67%. The results of the t-test are known, there is a difference of 6.25 in the knowledge variable from the results of the pre-test (41.50) and post-test (47.25), with a t value of 6.542, a significance of 0.001. There is a difference of 1.417 in the attitude variable from the results of the pre-test (36.42) and post-test (37.83), with a value of t = 1.535. Significance of 0.130. Conclusion: There is strong evidence that the media produced has a good performance in increasing knowledge, but has not been able to improve attitudes. For this reason, it needs to be refined to more optimal results.
The Effect of Hypnotherapy on Serum Cortisol Levels in Post-Cesarean Patients Rizkiani, Inne; Respati, Supriyadi Hari; Sulistyowati, Sri; Budihastuti, Uki Retno; Prasetya, Hanung
Journal of Maternal and Child Health Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.058 KB)

Abstract

Background: After cesarean section, there is often an increase in stress and anxiety which can have a negative effect on pain perception. Cortisol is the main stress hormone that regulates the duration and intensity of the stress response. Hypnotherapy is a therapy with a hypnotic method to reach someone's subconscious mind. Hypnotherapy is thought to be able to help patients in the post-section coping method because it can cause feelings of pleasure, satisfaction, safety, comfort and can make a person feel they have the strength of themselves to deal with the anxiety they experience. This study aims to analyze the effect of hypnotherapy on serum cortisol levels in postareaal section patients.Subjects and Method: This study was an experimental single-blind randomized controlled trial post-test group design which was conducted in the Obstetrics and Gynecology wards of Dr. Moewardi Hospital Surakarta and Dr. R Soetijono Blora Hospital. The subjects of the study were post-sectional patients who were hospitalized and met the inclusion and exclusion criteria. Subjects were divided into 2 groups, namely the hypnotherapy group which consisted of 15 post-sectional patients who received hypnotherapy and the control group which consisted of 15 postareaal patients who did not receive hypnotherapy. All subjects were examined for cortisol levels in the Prodia laboratory using the Chemiluminescent microparticle immunoassay (CMIA) method. The data of both groups were analyzed using the Mann-Whitney test.Results: The median, minimum, and maxi-mum cortisol levels in the hypnotherapy group were 3.60, 2.10, and 4.40 respectively, while the median, minimum and maximum cortisol values in the control group were 10.50, 8.20 and 32.80 respectively. Effect size= -2,2. The results of the analysis test showed a significant difference in mean values (p <0.001).Conclusion: Hypnotherapy has an effect on decreasing cortisol levels in post-cesarean section patients.Keywords: Hypnotherapy, Cortisol, Post-cesarean sectionCorrespondence: Inne Rizkiani. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret/ Dr. Moewardi Hospital, Sura-karta, Jl. Kolonel Sutarto, Jebres, Surakarta, Central Java 57126.Journal of Maternal and Child Health (2021), 01(03): 258-266https://doi.org/10.26911/thejmch.2021.06.03.01
Co-Authors - Soetrisno, - -, Soetrisno - . Soetrisno Abd. Rasyid Syamsuri Abdurahman Laqif Adhi Pribadi Adiyana, Febrian Andhika Agan, Lie Aji P Wibowo Aji P Wibowo, Aji P Akbar, Uchti Alamsyah, Meuthia Aldi Firmansyah Aldiansyah, Dudy Aldika Akbar, Muhammad Ilham Aloysius Suryawan Ambarini, Tinon Anak Agung Eka Andonotopo, Wiku Anik Lestari Anwar Sandi Wibowo, Anwar Sandi Ari Natalia Probandari Asih Anggraeni Astetri, Lini Bachnas, Muhammad Adrianes Bambang Arinekso Bambang Eko Wiyono, Bambang Eko Bambang Rahardjo Bambang Triono Cahyadi Besar, Dwi Sakti Berlian Besari Adi Pramono Cahyanto, Erindra Budi Carissa, Dinda Cut Meurah Yeni Damayanti, Sintia Dewanto Suryoningrat Dewi Setiyawati Donny Irawan Donny Irawan, Donny Dono Indarto Dympna Pramelita Endang Sri Kurniatun, Endang Sri Endang, Rini Enik Sulistyowati Eriana Melinawati Eric Edwin Yuliantara Erindra Budi Cahyanto Erlin Kiriwenno Evert Solomon Pangkahila Fajariyah, Luthfiana Firda Fibrila Firmansyah, Aldi Fitri, Niswatul Fitriana Fitriana Grandis, Bunga Silvia Hadi, Cahyono Hafi Nurinasari Hari Wujoso Hari Wujoso Herman Kristanto Heru Priyanto Heru Priyanto I Nyoman Hariyasa Sanjaya Ida Nurwati Isharyadi, Isharyadi John Arianto Sondakh, John Arianto Jonathan, Andreas Julian Dewantiningrum Khoeronisa, Siti Kurjak, Asim Kurniawan, Hendro Kusbianto, Kusbianto Kusnadi, Noferi Kusumaningsih, Damayanti Laqif, Abdurahman Lungguk Helen Alfian Tanjung Mahandaru, Araafi Hariza Marbun, Yohan Pamuji Mega, Aryanti Metharisa Sujana Muhammad Adrianes Bachnas Muhammad Akhyar Musyarofah, Nova Riyan Nababan, Ronald Nanik Setiyawati Nasrudin, Muhamad Ningrum, Wike Aprilia Nizar Hero K, Nizar Hero Nugraha, Gagah B Adi Nugroho, Muhammad Anggit Nurchalisha, Siti Nada Nurinasari, Hafi Nuswil Bernolian Nutria Widya Purna Anggraini Nuur, Aliffudin Pradana, Muhammad Denny Gagah Prameilita, Dympna Pramono, Mochammad Besari Adi Prasetya, Hanung Pujojati, Ferri Waluyo Wiwoho Putri, Nadhifa Kusuma Rahmawati, Oktantia Dyah Ridwan, Robert Rizka Pramudhita Rizkiani, Inne Rubin Enhui Tjiang Ryan Saktika Mulyana S Soetrisno Sapja Anantanyu, Sapja Saptaningtyas, Haryani Saputra, Ricky Bernadi Sesunan, Arfan Syahfani Siagian, Grace Siregar, Paulina Soetrisno Soetrisno Khasan, Soetrisno Soetrisno Soetrisno Soetrisno Soetrisno Soetrisno Soetrisno Soetrisno Soetrisno soetrisno soetrisno Soetrisno Soetrisno Soetrisno Soetrisno Soetrisno Soetrisno Stanojevic, Milan Subina, Totong Suhartini Sultoni Emillya Anggraeni Sumarno . Sunadi, Apri Supriyadi H Respati Supriyadi H Respati Supriyadi Hari R Supriyadi Hari Respati Supriyadi Hari Respati Supriyadi Hari, Supriyadi Suryoningrat, Dewanto Tarmizi Tarmizi Theresia Monica Rahardjo Tjiang, Rubin Enhui Uki Retno Budihastuti Wesliaprilius, Todung Antony Wiradnyana, Anak Agung Gede Putra Wiraswesty, Ika Wisdayanti, Syah Rini Wisnu Prabowo WISNU PRABOWO Yasir Avisena Yuliani, Saffana Oka Yulyanti, Yulyanti Yuniarsih Zakia, Yuniarsih Yuniarti Yuniarti Yusuf Antoni, Yusuf