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Cost-Effectiveness Analysis Terapi Antibiotik Seftriakson dan Sefotaksim Pada Pasien Tifoid di RSUD Dr. M.M Dunda Limboto Tuloli, Teti Sutriyati
Jambura Journal of Educational Chemistry Vol 12, No 1 (2017): Februari
Publisher : Jambura Journal of Educational Chemistry

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Abstract

Tifoid merupakan penyakit infeksi yang disebabkan oleh bakteri Salmonella typhi dan telah banyak menginfeksi masyarakat baik di perkotaan maupun pedesaan. Dengan adanya fenomena multidrug resistance Salmonella typhi maka pemilihan terapi antibiotik yang efektif pada tifoid menjadi faktor yang harus diperhatikan selain kendala biaya. Penelitian ini bertujuan untuk mengetahui efektivitas biaya pada terapi dua antibiotik yaitu seftriakson dan sefotaksim yang digunakan dalam pengobatan demam tifoid di RSUD DR. M.M Dunda Limboto. Penelitian ini dilakukan dengan menggunakan metode survei analitik dengan desain cross sectional. Penelitian ini menggunakan data sekunder pasien demam tifoid periode Januari-Desember 2014. Data yang diambil meliputi, data demografi, lama rawat inap, dan data keuangan pasien. Hasil penelitian menunjukkan bahwa kelompok terapi antibiotik seftriakson lebih cost effective yaitu dengan biaya Rp 3.650.091 dengan lama rawat inap 2,8 hari dibandingkan dengan kelompok terapi antibiotik sefotaksim dengan biaya lebih besar yaitu Rp 4.036.015 dengan lama rawat inap 3,7 hari.
PENINGKATAN KELARUTAN PENTAGAMAVUNON-0 DENGAN PENAMBAHAN TWEEN 80 Tuloli, Teti Sutriyati
Sainstek Vol 4, No 2, 2009
Publisher : Sainstek

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Abstract

Dissolution of drug substance represent one of important conditions in pharmacy area especially in formulation of a drug form. If we like to reach the good imbibition, drug have to stay in the dissolve form, therefore dissolution speed represent the determinant of imbibition speed for the drugs of which difficult to dissolve. Pentagamavunon-0 represent the analogous of kurkumin owning dissolution very small in water. therefore needed an approach in the effort this improvement pentagamavunon-0 with the technique of addition by substance of nonionic surfactan tween 80. To know the ability tween 80 in improving dissolution pentagamavunon-0 done by test of dissolution pentagamavunon-0 with the filtration method in condensation tween 80 rate 3,82 x 10-3M; 7,63 x 10- 3M; 1,53 x 10-2M; 2,29 x 10-2M; 3,05 x 10-2M at temperature 37, 45, 60 C [0,5 C]. Statistic analysis which we used is Kruskal-Wallis H method continued with the Median test. Result of research show the existence of difference meaning of the result test dissolution pentagamavunon-0 at various rate tween 80 (Sig =0,27) and different temperature (Sig.= 0,05) with the highest dissolution pentagamavunon-0 at the addition tween 80 rate 3,82 x 10-3M. React between pentagamavunon-0 and tween 80 happened in exothermic (?H= -13,42554 kal / mole) and spontaniously (?F = - 4857,21; - 4378,66 ; and - 4138,72 kal / mole). Interaction that happened especially entangle the interaction of pattern physical induce pentagamavunon-0 by tween 80 and the solubilisation process happened in the later area palisade continued in the center misel.
Pemberdayaan Dan Pemanfaatan Tanaman Toga untuk Produk Minuman Immunostimulan di Masa Pandemi Covid 19 Tuloli, Teti S; Taupik, Muhammad
Jurnal Sibermas (Sinergi Pemberdayaan Masyarakat) Vol 9, No 2 (2020): Jurnal Sbermas (Sinergi Bersama Masyarakat)
Publisher : Univeristas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/sibermas.v9i2.7984

Abstract

Kondisi di lapangan menunjukkan bahwa selama ini pemanfaatan dan pengelolaan sumberdaya perdesaan sebagian besar dilakukan oleh laki-laki, mulai dari kegiatan di bidang pertanian, peternakan, industri kecil dan menengah, koperasi, dan kegiatan lain yang sifatnya kegiatan ekonomi. Padahal perempuan sebagai anggota masyarakat juga mempunyai hak untuk ikut serta dalam pemanfaatan dan pengelolaan sumberdaya perdesaan, meskipun kemungkinan peran perempuan tidak sebesar peran laki-laki. Oleh karena itu diperlukan adanya berbagai program yang dapat dilakukan perempuan dalam rangka peningkatan kesejahteraan keluarga dengan memanfaatkan dan mengelola lingkungan sekitarnya. Salah satu program yang dapat dilaksanakan oleh perempuan dalam upaya peningkatan kesejahteraan industri rumah tangga, khususnya di bidang pangan adalah program penanaman dan pemanfaatan Tanaman Obat Keluarga (TOGA).Tujuan dari pengabdian ini adalah meningkatkan pendapatan masyarakat  dimasa pandemi covid 19 sekaligus menyediakan obat yang lebih murah dan efek samping yang lebih ringan. Metode yang digunakan adalah ceramah dan praktik atau demonstrasi. Sehingga masyarakat dapat mempraktikkan secara langsung dan menerapkan dalam  rumah tangga. Dalam pelaksanaannya disampaikan metode pengolahan tanaman TOGA sehingga menjadi minuman immunostimulan yang menyehatkan maupun bagaimana cara menanamnya. Disamping itu juga bagaimana cara mengelola keuangan hasil penjualan hasil pengelohan tanaman TOGA tersebut. Bagaimana strategi pemasarannya kepada masyarakat atau konsumen yang membutuhkan sehingga bisa menghasilkan keuntungan.
ANALISIS EFEKTIVITAS BIAYA TERAPI ANTIHIPERTENSI AMLODIPIN DIBANDINGKAN DENGAN CANDESARTAN PADA PASIEN HIPERTENSI RAWAT JALAN DI RSUD TOTO KABILA Madania, Madania; Tuloli, Teti Sutriyati; bangol, asnia asnia
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11368

Abstract

Hipertensi merupakan penyakit tidak menular yang ditandai dengan terjadinya peningkatan tekanan darah sistolik dan diastolik yang lebih dari 140 mmHg dan 90 mmHg. Penelitian farmakoekonomi merupakan proses identifikasi, pengukuran dan perbandingan biaya, akibat dan keuntungan suatu program pelayanan dan terapi, serta menentukan pilihan mana yang memberikan outcomes kesehatan terbaik untuk sumber yang diinvestasikan. Analisis yang digunakan adalah Analisis Efektivitas Biaya untuk menentukan rekomendasi terapi terbaik. Penelitian ini bertujuan untuk mengetahui penggunaan antihipertensi Amlodipin dibandingkan Candesartan, biaya terapi yang dikeluarkan pasien, dan antihipertensi yang paling efektiv biaya. Penelitian ini bersifat deskriptif analitik secara retrospektif, subyek penelitian adalah pasien hipertensi yang menggunakan terapi Amlodipin dan Candesartan sebanyak 46 pasien yang memenuhi kriteria inklusi. Data diolah menggunakan ACER dan ICER. Hasil Penelitian menunjukkan jumlah pasien hipertensi lebih banyak diderita oleh perempuan yaitu 27 orang dengan persentase 58,7%, berdasarkan usia pada kelompok 51-60 tahun pada perempuan yaitu 14 orang dengan persentase 51,9%. Efektivitas pengobatan Amlodipin 86,36%, dan Candesartan 75%. Berdasarkan nilai ACER yang paling cost effective adalah Candesartan dengan nilai ACER sebesar Rp 2.113,58 per % efektivitas.
PROFIL TERAPI OBAT PADA PASIEN ISPA DI PUSKESMAS KOTA TENGAH TAHUN 2019 Sutriyati Tuloli, Teti; Rasdiana, Nur; Bakululu, Lesmiyati
Indonesian Journal of Pharmaceutical Education Vol 2, No 1 (2022): Januari-April 2022 (in press)
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i1.10980

Abstract

Acute respiratory infections (ARI) is an infectioan that commonly occurs in human of any age however, children and infants are the most vulnerable and most exposed to ARI. The study aims to identify the utilization of drug therapy in patients with ARI, specifically those infants and children patients at Puskesmas Kota Tengah in 2019. it employs a descriptive research design where the obtained data are secondary data that are collected retrospectively besides, the data used in this study are medical prescription documents, including the patient’s name, age, type of drug used, and drug use patternThe finding discloses that drug therapy administered to 116 infants and children patients who suffer from ARI at Puskesmas Kota Tengah in 2019 reveals that the most widely used therapy is the expectorant group(Gliceryl Guaicolate) as many as 61 (62,2%), Antihistamine group (Chlorpheniramine maleate) with a frequency of 75 times (64,1%), Vitamin B Complex with a frequency of 69 times (55,2%), Antibiotik group (Amoxicillin) with a frequency 47 times (41%), Analgesic and Antipyretic group (Paracetamol) is the most widely prescribed with a prescription frequency of 65 times (55,7%). In addition, the parameter of right drug obtains frequency of 22 times with 94 times with the percentage of (81,0%) and incorrect drug obtains a frequncy of 22 times with a percentage of (19,0%), the parameter of right dose for 83 times with a percentage of (71,6%), and incorrect dose for 33 times with a percentage of (28,4%). At the same time, the right drug use pattern parameter involves the right dose, and the right drug obtains a frequency of  94 times with a percentage 0f 8 (81,0%) while the incorrect drug use pattern obtains a frequency 0f 22 times with a percentage 0f (19,0%)
Analisis Manajemen Pengelolaan Logistik Sediaan Farmasi dan Perbekalan Kesehatan di Instalasi Farmasi Widy Susanti Abdulkadir; Madania Madania; Teti S. Tuloli; Nur Rasdianah; Juliyanty Akuba
Indonesian Journal of Pharmaceutical Education Vol 2, No 1 (2022): Januari-April 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i1.11399

Abstract

Drug management is a set of optimally conducted activities related to the aspects of drug planning, procurement, storing, distribution, and extermination. This was done to achieve the proper drug amount, types, supply, maintenance, and medication. Earlier observstion revealed problems in managing pharmaceutical stock and consumables, where some of the stocks are empty. This qualitative descriptive research focus on identifying pharmaceutical logistic stock and health supplies comprising drug planning, procurement, storing, distribution, and extermination in the pharmaceutical unit of Gorontalo. The primary data were obtained from questionnaires based on technical guidance by the health ministry while the secondary were obtained from related documents. Based on the findings, the pharmaceutical stock planning and storing process at the pharmacy unit did not meet the health ministry standards, which is opposite to the procurement, distribution, and extermination process.
Evaluasi Kesesuaian Peresepan Obat Pada Pasien Poliklinik Penyakit Dalam Terhadap Formularium di Rumah Sakit Teti Sutriati Tuloli; Madania Madania; Nur Rasdianah; Indah Pramesty Gobel
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.14219

Abstract

National formulary is a list of medicines compiled by a national committee established by the Minister of Health based on cutting-edge, efficacious, safe, and affordable scientific evidence referred for drug use by national health insurance. This study aims to determine the evaluation of drug prescribing in the Hospital formulary. This retrospective study involved subjects qualified for the inclusion criteria i.e. 73 sheet recipes in August - December 2019. some prescribed drugs that are not listed in the hospital formulary in the following percentage: August (100%), September (60%), October (50%), November (81%), and December (65%) with the average of 71%. This indicates that the prescription does not conform to the hospital formulary regulation of 100%. In conclusion, there are some drugs prescribed by the doctor that is not conformed to the hospital formulary, which means tight supervision for the prescribing is required.
Tingkat Pengetahuan Pasien Penderita Tuberculosis Dalam Program Pengobatan Tuberculosis di Puskesmas Madania Madania; Mahdalena Sy Pakaya; Teti Sutriati Tuloli; Widysusanti Abdulkadir
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.14220

Abstract

Tuberculosis is an infectious disease caused by bacteria known as mycobacterium tuberculosis. In Indonesia, tuberculosis is the third common public health problem the prevalence of the disease in this country is among the highest in the world after China and India. Sufficient knowledge of diseases and medicines correlates with the result of therapy in general. Knowledge about drugs is important for patients since it helps them to consume drugs properly (which result in maximum therapy) and to avoid complications. The purpose of this descriptive study is to determine the level of knowledge of patients suffering from tuberculosis in the tuberculosis treatment program at Bulango Utara Puskesmas (Community Health Center) by a questionnaire. It applied a cross-sectional approach with primary data obtained from the result of a sample questionnaire totaling 24 patients taken by saturated sampling. The result of this present study reveal that the level knowledge of patients with tuberculosis in the area is still relatively low at 75%, while only 25% is classified as moderate.
Evaluasi Mutu Pelayanan Kefarmasian Berdasarkan Standar Pelayanan Minimal (Spm) Di Instalasi Farmasi Teti Sutriyati Tuloli; Widy Susanti Abdulkadir; Nur Rasdianah
Journal Syifa Sciences and Clinical Research Vol 3, No 2 (2021): Volume 3 Edisi 2 2021
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v3i2.9668

Abstract

Quality refers to compliance with predetermined standards or by requirements. The minimum service standard (MSS) in the health sector at the hospital is crucial because it is a measure of the hospital's performance of health services. This study was intended to describe the service quality in the pharmacy installation of Toto Hospital in Kabila based on four indicators of minimum pharmacy service standards, viz. drug waiting time for treatment completion, the absence of drug administration errors, customer satisfaction, and prescription writing according to the formulary. This descriptive cross-sectional research involved 154 outpatients and inpatients for the category of prescription writing according to the formulary and 154 outpatients for other categories as respondents as samples. Besides, the instruments were a customer satisfaction questionnaire and observation sheet. The results showed that the indicators of waiting time were nine minutes seven seconds and 18 minutes six seconds for concocted drug treatment; there was no error in administering drugs by 100%; customer satisfaction was 86.9%, and; prescription writing according to the formulary was 92.7%. . It was concluded that the Pharmacy Installation of Toto Hospital had not met the specified Minimum Service Standards (MSS).
Studi Penjaminan Mutu (Quality Assurance) Dalam Pelayanan Kefarmasian di Apotek Nurchamidin Gobel; Teti S. Tuloli; Madania Madania
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.13956

Abstract

Low Quality Assurance in Pharmacy Award Ipilo Gorontalo include pharmaceutical, security, procurement, storage, and distribution or drug delivery, drug management, on a prescription drug services, drug information services, as well as drug development, medicinal materials and traditional medicine. The impact of the implementation of activities in the pharmacy pharmacy services Anugerah Ipilo errors may occur treatment (medication errors) in the service process. Quality Assurance (QA) is one dimension that is used in the measurement of quality of service, where the application of QA in pharmacies Ipilo Award aims to provide quality assurance of pharmaceutical products and the quality of services provided to patients. This research is descriptive, the source of primary data obtained from the questionnaires with QA standard indicator framework on pharmaceutical services in pharmacies Anugerah Ipilo. The assessment results then classified based on criteria appropriate, relatively appropriate and not appropriate. The results showed that the Quality Assurance (Quality Assurance) on the quality of the equipment and the safety assurance of Pharmaceutical Services in Pharmacy Award Ipilo there are seven questions (70%) had a very good criteria, three questions (30%) had a good criterion. Quality Assurance (Quality Assurance) on the Process of Pharmaceutical Services in Pharmacy Award Ipilo there are 4 questions (40%) had a very good criteria, one question (10%) had a pretty good and 5 questions (50%) had less good. Pharmacies merely focused on the administration and management of medication alone is not the overall pharmacy services, in addition because the pharmacy Anugerah Ipilo prefer the function of the economy (business) rather than its social function, which pharmacies are required to gain / profit in business.
Co-Authors Adam Mustapa, Muhammad AinunSusanto, Iffanda Nur Akuba, Juliyanti Alamri, fahira rais Andi Makkulawu Anggai, Rifka Anggraini Anggraini, Diva Nur Ariani H. Hutuba Asriana Basrudin Asriastuti, Andi Nabirah Bakululu, Lesmiyati bangol, asnia asnia Datu, Novanza L.M.N Datu, Yunita Devie Ariany Daud Divia Handayani Mudjidu Djayadi Azis Djuarno, Endah Nurrohwintah dwi pratiwi, susi Endah Nurrohwinta Djuwarno Evania P. Tuli Fika Nuzul Ramadhani Gubali, Derina Dwifrila Ridhani Hamzah, Alifiah Ramawaty Hidayat Ahmad Hiola, Faramita Hutuba, Ariani Igirisa, Fitriwiah Indah Pramesty Gobel Indriatawati, Jihan Julianti, Natasya Melly Julianty Akuba Jumantrin, Nur Fitriah Kahar, Putri Kartika Adhilia Kujiman, Kerin Vivian LATIF, MULTIANI S Latif, Multiani S. Madania Madania . Madania, Madania Madania, Madania Maghfiroh, Adinda Nur Mahdalena Sy Pakaya Makkulawu, Andi Manno, Mohamad Reski MAYANG, NURUL HANDAYANTI Moh. Rivai Nakoe Mohamad Aprianto Paneo Mo’o, Faradila Ratu Cindana Muhammad Taupik Multiani S Latif Musawir, Sadam Nur Ain Thomas Nur Rasdianah Nurain Abdullah Nurchamidin Gobel Nurkamiden, Sri Devi Maharani Otoluwa, Siti Zahra Pakaya, Adela pakaya, Handriansyah Pakaya, Lutfiah Pakaya, Nikmasari Papeo, Dizky Ramadani Putr Papeo, Dizky Ramadani Putri Paputunngan, Mitha Puhi, Melly Agustin Is Puluhulawa, Lisa Efriani Rahmayani, Siti Farah Rasdiana, Nur Reski Manno, Mohamad Robert Tungadi Rombe, Nensy Toban Sapiun, Zulfiayu Sarinah Basri K Selong, Siti Ruwaida D. Siti Rakhmatia Paramita Th. Kum Sumaga, Khairunnisa Alya Sunarto Kadir Suswanti Thomas , Nur Ain Tolulu, Sri Noviani Tri Bella Angraini Suwandi Usuli, Tirta Chanisa Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widysusanti Abdulkadir Yahya, Fiantika Ambadar Yusuf, Wahyuni Adrian Zulkifli B. Pomalango