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All Journal Jurnal Kedokteran Diponegoro Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Althea Medical Journal Universa Medicina Jurnal Kreativitas PKM Jurnal Medika Malahayati Jurnal Biomedika dan Kesehatan Veterinary Biomedical and Clinical Journal JUARA: JURNAL WAHANA ABDIMAS SEJAHTERA Jurnal AKAL: Abdimas dan Kearifan Lokal JURNAL ABDI MASYARAKAT INDONESIA (JAMIN) Neurona Jurnal Pengabdian Masyarakat Trimedika Poltekita: Jurnal Ilmu Kesehatan International Journal of Health and Medicine
Hairunisa, Nany
Department Of Occupational Medicine, Faculty Of Medicine, Universitas Trisakti, Jakarta, Indonesia
Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Transportation Veterinary Other

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Mouse Models in Autoimmune Disease Studies: Reproducibility and Clinical Applications Muhammad Faldy Abdul Aziz; Malika Adira Hasri; Nany Hairunisa; Nor Azlina Khalil; Rodiah Mohd Radzi; Dyah Ayu Woro Setyaningrum
International Journal of Health and Medicine Vol. 3 No. 1 (2026): January : International Journal of Health and Medicine
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhm.v3i1.592

Abstract

Objective: Autoimmune diseases are complex disorders that arise when the immune system loses tolerance to self-antigens, leading to chronic inflammation and tissue damage. To understand disease pathogenesis and to evaluate therapeutic efficacy, animal models are widely used in autoimmune research. This review aims to analyze various types of animal models employed in studies of autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), type 1 diabetes mellitus (T1DM), and multiple sclerosis (MS), with a particular focus on reproducibility and clinical applicability. Methods: This study was conducted through the selection and analysis of scientific literature published over the last ten years (2015–2025), using specific keywords including “clinical application,” “autoimmunity,” “animal models,” “humanized mice,” “lupus,” “rheumatoid arthritis,” “reproducibility,” and “translational research.” Literature searches were performed in major databases such as Google Scholar, PubMed, ScienceDirect, and Scopus. Results: Spontaneous models, such as NOD and MRL/lpr mice, exhibit close resemblance to human disease pathogenesis but are influenced by strain variability and environmental factors. Induced models, including collagen-induced arthritis (CIA) and experimental autoimmune encephalomyelitis (EAE), allow greater control over disease onset but do not fully capture the clinical complexity observed in humans. Humanized models demonstrate high translational relevance; however, their use is constrained by high costs and technical limitations. Conclusion: No single animal model is universally ideal for studying autoimmune diseases. Model selection should be based on biological relevance, reproducibility of outcomes, and the potential for clinical translation in autoimmune disease research.
Melindungi Kulit: Tinjauan Komprehensif tentang Tabir Surya Anorganik dan Perannya dalam Fotoproteksi Al-Sayed, Raghda; Ahmed, Dena; Zainulabdeen, Khalid; Waleed, Reem; Bufaroosha, Muna; Hairunisa, Nany; Lestari, Ade Dwi; Widowati, Henie; Ridwan, Alvin Mohamad; Anestessia, Ira Juliet; Yousif, Emad; Panduwati, Lira; Mayasari, Atut Cicih
Jurnal Biomedika dan Kesehatan Vol 8 No 3 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2025.v8.359-373

Abstract

Sunscreens are topical agents that protect the skin from the damaging effects of ultraviolet (UV) radiation, a major contributor to premature aging and skin cancer. These products are typically categorized into two main types: physical (inorganic or mineral) and chemical (organic) sunscreens. Physical sunscreens primarily consist of zinc oxide (ZnO) and titanium dioxide (TiO₂), which reflect and scatter UV rays, thereby providing broad-spectrum protection. Compared with chemical sunscreens, which absorb UV radiation and convert it into heat, inorganic agents are associated with a lower risk of systemic absorption and skin irritation, making them particularly suitable for sensitive skin and pediatric use. This review explores the fundamental mechanisms of action, formulation challenges, and comparative effectiveness of inorganic sunscreens. Special attention is given to their photostability, which contributes to longer-lasting protection, and to their safety profiles in both acute and chronic use. Additionally, recent innovations in nanoparticle technology have enhanced the aesthetic appeal of these agents by reducing visible residue. However, this has also raised new concerns about nanoparticle penetration and environmental impact. Finally, the review addresses public health considerations, including regulatory updates, consumer preferences, and the role of education in promoting informed use of sunscreen.
Embolisasi Pra Operatif Untuk Angiofibroma Nasofaringeal Abdillah, Fauzan; Nugroho, Dwi Agustawan; Fadillah, Ibnu Harris; Mashabi, Yasmine; Hairunisa, Nany; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 8 No 3 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2025.v8.334-349

Abstract

Background: Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign vascular tumor that almost exclusively affects adolescent males. Despite its benign nature, JNA demonstrates locally aggressive behavior and is associated with significant intraoperative bleeding. Preoperative embolization has become an important modality to reduce tumor vascularization and minimize intraoperative blood loss. The Objective of this case report is to discuss the role of preoperative embolization in the management of JNA, including relevant vascular anatomy, embolic materials, benefits and limitations, as well as local case experiences in Indonesia. Methods: A literature review was conducted on the external carotid artery anatomy, etiology, epidemiology, histopathology, tumor spread and staging, and preoperative embolization techniques using various materials such as gelfoam, polyvinyl alcohol, ethanol, and microspheres. Additionally, two cases of JNA at Cipto Mangunkusumo Hospital were reported, both treated with preoperative embolization using gelfoam prior to transpalatal tumor resection. Results: In both cases, embolization successfully reduced tumor vascularity. However, due to surgical delay beyond 48 hours after embolization, intraoperative bleeding remained significant (800–1000 mL). Both patients recovered uneventfully without postoperative complications, and histopathological findings confirmed JNA. Conclusion: Preoperative embolization is effective in reducing intraoperative blood loss during JNA surgery and should ideally be performed within 24–48 hours before resection. This approach facilitates safer tumor removal, although its optimal success depends on timing, embolization technique, and operator expertise.
PENINGKATAN PENGETAHUAN K3 UNTUK PENCEGAHAN PENYAKIT AKIBAT KERJA PADA PETERNAK AYAM CIAMBAR Hairunisa, Nany; Lestari, Ade Dwi; Ridwan, Alvin Mohamad; Ab. Razak, Asreene Binti; Putri, Fania Sabila; Syafitri, Julia Aina; Amirrudin, Danial Arif Bin; Asrani, Iffah syahidah Binti
Jurnal Pengabdian Masyarakat Trimedika Vol. 3 No. 1 (2026)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v3i1.23142

Abstract

Occupational diseases  remain a significant public health issue in various sectors, including small-scale poultry farming. In Ciambar Village, Sukabumi, chicken farmers are exposed to a variety of occupational hazards due to the absence of health evaluations and limited awareness of occupational health and safety. This community service program aimed to increase knowledge and awareness of occupational health and disease prevention among poultry farmers through educational counseling. The activity involved a health education session, supported by visual aids and interactive discussions. A pre-test and post-test were used to evaluate knowledge gain. Results showed a substantial increase in participants' knowledge, with post-test scores rising from 13% to 83%. These findings suggest that targeted educational interventions can significantly improve workers’ understanding of occupational hazards and encourage healthier work practices
EDUKASI KESEHATAN MATA UNTUK MENCEGAH KEBUTAAN AKIBAT KELAINAN REFRAKSI PADA PENDUDUK PONDOK AREN-TANGERANG Adiwardhani, Anggraeni; Hairunisa, Nany; Mashab, Yasmine; Zaina, Nashita Amira; Amalia, Husnun
Jurnal Pengabdian Masyarakat Trimedika Vol. 3 No. 1 (2026)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v3i1.25869

Abstract

Latar Belakang Indonesia adalah negara kepulauan terbesar di dunia dan masalah kesehatan mata masih menjadi sesuatu yang belum dapat diselesaikan arena sirtuasi geografis dan demografis. Terdapat 0,4% angka kebutaan pada penduduknya, dan 80% adalah kebutaan yang dapat dicegah atau diobati dan refraksi adalah menjadi penyebab utama (42%). Kelainan refraksi sampai saat ini masih menjadi tantangan kesehatan masyarakat karena menjadi penyebab gangguan penglihatan yang paling besar dan mengenai seluruh kelompok usia dan percepatan terjadinya gangguan penglihatan pada berusia produktif akan merugikan perekonomian negara karena terganggunya sumber daya manusia. Fakultas Kedokteran Universitas Trisakti dan masyarakat dapat membantu berpartisipasi pada program ini dengan melaksanakan pengabdian skrining Kesehatan mata dan memberikan tatalaksananya agar mencegah kebutaan akibat kelainan refraksi khususnya. Metode Kegiatan pengabdian diikuti oleh 136 peserta, dilakukan penyuluhan, anamnesis, pemeriksaan Kesehatan mata termasuk pemeriksaan refraksi. Kacamata diberikan bagi peserta yang memerlukan. Hasil Peserta berusia anatara 3 tahun sampai 71 tahun, dengan 83,1% adalah laki-laki dan 16,9% adalah perempuan dan Sebagian besar peserta tidak memiliki pekerjaan (41,9%). Sekitar 42,6% memiliki Riwayat pengguna kacamata namun yang membutuhkan kacamata adalah 57,4% peserta. Setelah dilakukan edukasi terdapat peningkatan pengertian pentingnya mengkoreksi penglihatan dengan kacamata dari 50% menjadi 85%. Kesimpulan Pada 136 penduduk kurang mampu di Pondok Aren, 57,4% memerlukan kacamata untuk memperbaiki penglihatannya.
Program Penyuluhan Pencegahan HIV AIDS untuk Pekerja Migran Indonesia di Penang, Malaysia Alvina, Alvina; Mashabi, Yasmine; Amalia, Husnun; Hairunisa, Nany; Pratiwi, Luh Ade Dinda Pradnya; Rahman, Athaya Nayla Pasca; Irawan, Achmad
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 9, No 4 (2026): Volume 9 Nomor 4 (2026)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v9i4.24877

Abstract

ABSTRAK Pekerja Migran Indonesia (PMI) merupakan kelompok masyarakat yang memiliki kerentanan tinggi terhadap berbagai masalah kesehatan, termasuk penyakit menular seperti HIV/AIDS. Kondisi kerja yang berat, mobilitas tinggi, keterbatasan akses terhadap layanan kesehatan, serta rendahnya pengetahuan tentang faktor risiko penularan HIV/AIDS menjadi faktor yang meningkatkan potensi terjadinya penularan pada kelompok ini. Selain itu, stigma dan diskriminasi terhadap HIV/AIDS masih menjadi hambatan utama bagi PMI untuk memperoleh informasi dan melakukan pemeriksaan kesehatan secara mandiri. Minimnya edukasi kesehatan reproduksi dan penyakit menular menyebabkan sebagian PMI tidak menyadari perilaku berisiko yang dapat memicu penularan HIV/AIDS, seperti hubungan seksual tidak aman, penggunaan alat suntik tidak steril. Kegiatan ini diharapkan dapat meningkatkan pengetahuan PMI mengenai HIV/AIDS, mendorong perubahan perilaku ke arah yang lebih sehat dan aman, serta meningkatkan akses terhadap layanan kesehatan preventif. Kegiatan ini juga berkontribusi dalam upaya pencegahan penularan HIV/AIDS baik di negara penempatan maupun saat PMI kembali ke Indonesia. Pada kegiatan ini digunakan metode penyuluhan serta dilakukan test berupa pre dan post test. Pada kegiatan penyuluhan ini diikuti oleh 40 peserta dengan mayoritas peserta adalah perempuan sebanyak 85% dan umur dewasa 19-44 tahun sebanyak 55%. Pada hasil pretest didapatkan mayoritas peserta mempunyai pengetahuan kurang mengenai HIV AIDS sebanyak 87,5%, tetapi setelah dilakukan penyuluhan dan diberikan post test, ternyata yang pengetahuannya kurang menjadi 25%. Pengetahuan para pekerja migran tentang HIV AIDS menjadi lebih baik setelah diberikan penyuluhan. Penyuluhan merupakan salah satu metode yang cukup efektif dalam meningkatkan pengetahuan seseorang. Kata Kunci: Pekerja Migran Indonesia, Penyuluhan, HIV AIDS.  ABSTRACT Indonesian Migrant Workers (IMW) are a population group highly vulnerable to various health problems, including infectious diseases such as HIV/AIDS. Harsh working conditions, high mobility, limited access to health services, and low knowledge about risk factors for HIV/AIDS transmission increase the potential for transmission in this group. Furthermore, stigma and discrimination against HIV/AIDS remain major barriers for IMW in obtaining information and conducting independent health checks. The lack of education on reproductive health and infectious diseases results in some IMW being unaware of risky behaviors that can trigger HIV/AIDS transmission, such as unsafe sex and the use of non-sterile injection equipment. This activity is expected to increase PMI knowledge about HIV/AIDS, encourage healthier and safer behavior changes, and increase access to preventive health services. This activity also contributes to efforts to prevent HIV/AIDS transmission both in the host country and upon PMI's return to Indonesia. This activity used counseling methods and conducted pre- and post-tests. This outreach activity was attended by 40 participants with the majority of participants being women (85%) and adults aged 19-44 years (55%). The pretest results showed that the majority of participants had lack of knowledge about HIV AIDS (87.5%), but after the counseling and the post-test, that those with lack of knowledge became 25%. Migrant workers' knowledge about HIV AIDS improved after being given counseling. Counseling is a quite effective method in increasing a person's knowledge. Keywords: Indonesian Migrant Workers, Counseling, HIV AIDS
Co-Authors Ab. Razak, Asreene Binti Abikusno, Revalita Adhiwardan, Anggraeni Adianto, Raymond Adlani, Hadianti Agil, Nadifa Ahmed, Dena Ahmed, Dina Al-Sayed, Raghda Alsayed, Raghda Alvin M. Ridwan Alvina Alvina Amirrudin, Danial Arif Bin Anastasya, Karina Shari Anestessia, Ira Juliet Anggiat, Desi Anggraeni Adiwardhani Angham G Hadi Ariyani, Aziza Asrani, Iffah syahidah Binti Aswar, Andini Atut Cicih Mayasari Briliant, Permaisonya Bufaroosha, Muna Cylla Revata David Tjahyadi dianawati, dianawati Djebli, Noureddine Dwi Lestari, Ade Dyah Ayu Woro Setyaningrum Emad Yousif Emad Yousif Eric Fahed Faza Erlani Kartadinata, Erlani Fadillah, Ibnu Harris Fadlyah, Nur Ashfiya Faradila, Meutia Atika FAUZAN ABDILLAH Florinda Ilona Gerie Amarendra Grace Nerry Legoh Hadi Sumarsono Hameed, Seenar Hari Krismanuel Hosea Jaya Edy Husain, Amani Husnun Amalia Irawan, Achmad Irmiya Rachmiyani Isahak, Marzuki bin Iskandar, Dian Joice Viladelvia Kalumpiu, Joice Viladelvia Julian Chendrasari Kadhom, Mohammed Karina Shari Anastasya Kencana, Gita Khairunisa, Adinda Kudaer, Nuha B Larasari, Andira LEKOK, WIDYAWATI Lestari, Ade Dwi Lie T. Merijanti Lie Tanu Merijanti, Lie Tanu Liman, Patricia Budihartanti Magdalena Wartono Maharani, Ni Putu Radela Maharani, Ronaningtyas Mahdi, Sarah Malika Adira Hasri Mario Mario Marja, Triyoko Septio Mashab, Yasmine Mashabi, Yasmine Meiriani Sari Meiyanti Meiyanti, Meiyanti Mohamad Ridwan, Alvin Mohammed Kadhom Mohammed Kadhom Mohsen Hashim Risan Muhammad Faldy Abdul Aziz Mulia Rahmansyah Natadidjaja, Ronald Irwanto Nor Azlina Khalil Nugroho Abikusno Nugroho, Dwi Agustawan Nuha Kudaer Oladimeji, Ashaolu Victoria Panduwati, Lira Parwanto, Edy Patricia Budihartanti Liman Pertiwi, Iin Indra Pramesti Indri Miranti Prasetyaningsih, Noviani Pratiwi, Luh Ade Dinda Pradnya Primandari, Rima Anindita Purnamawati Tjhin Purnamawati Tjhin, Purnamawati Pusparini Pusparini Putri, Fania Sabila Raheem, Rasha Rahman, Athaya Nayla Pasca Rantung, Alvin Lekonardo Rasha Raheem Redwan, Amamer M Ridwan Harrianto Ridwan, Alvin Mohamad Ridwan, Alvin Muhamad Rima Anindita Risan, Mohsen Hashim Rita Khairani, Rita Rodiah Mohd Radzi Sabrina, Isra Salman, Israa Samira, Jihan Setyaningrum, Dyah Ayu Woro Sri Mulyani Sudarma, Verawati Syafitri, Julia Aina T, Febrina Thamer, Hamsa Tjahjadi, Muljadi Tjam Diana Samara Tubagus Ferdi Fadilah, Tubagus Ferdi Verawati Sudarma Waleed, Reem Wawan Kurniawan Widowati, Henie Witjaksana, Riani YENNY YENNY Yousif, Emad Yudhisman Imran Yuliana Yuliana Yusop, Rahimi M Zaina, Nashita Amira Zainulabdeen, Khalid