Claim Missing Document
Check
Articles

Penyuluhan Hormon Paratiroid, Kalsitonin, dan Obat yang Bekerja pada Tulang di SMAN 1 Karawang Munir Alinu Mulki; Rizki Rava Dwi Putra; Jasmine Rahma Saputri; Siti Rosilfa Marisa; Ihsan Alfiandri
Jurnal Dorkes (Dedikasi Olahraga dan Kesehatan) Vol 1 No 2 (2023): DORKES Edisi September 2023
Publisher : Fakultas Ilmu Kesehatan UNSIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/dorkes.v1i2.10449

Abstract

Kalsium merupakan mineral yang paling penting bagi berbagai fungsi di dalam tubuh. Kelenjar paratiroid dan tiroid bertanggung jawab mengatur kadar kalsium dalam tubuh dengan cermat. Penyusunan jurnal ini ditujukan untuk mengamati pengetahuan siswa SMAN 1 Karawang terkait pengetahuan tentang hormon paratiroid, kalsitonin beserta obat yang bekerja pada tulang, karena berdasarkan survei yang telah dilakukan diketahui bahwa siswa-siswa SMAN 1 Karawang kurang memahami mengenai pengetahuan hormon paratiroid, kalsitonin beserta obatx yang bekerja pada tulang. Metode yang diterapkan adalah metode tes untuk menguji kemampuan responden berupa pemberian Pre-Test dan Post-Test, data tes tersebut diolah menggunakan aplikasi SPSS. Hasil Post-Test menggambarkan bahwa terdapat kenaikan nilai sebanyak 18,4% setelah dilakukan kegiatan penyampaian materi. Hal ini dapat diketahui dari nilai hasil rata-rata Pre-test 5,58 dan setelah dilakukan penyuluhan terdapat peningkatan nilai rata-rata Post-test menjadi 7,42. Dengan demikian, dapat disimpulkan bahwa penyuluhan kesehatan memiliki dampak signifikan terhadap pengetahuan siswa-siswi di SMAN 1 Karawang mengenai hormon paratiroid, kalsitonin beserta obat yang bekerja pada tulang.
Perbandingan Efektivitas Antibiotik Terhadap Durasi Terapi Demam Tifoid Sholih, Mally Ghinan; Mulki, Munir Alinu; Nurhadis, Nurhadis; Akifah, Muthia Nur; Aprillia, Cantika; Maharani, Puteri Rahma; Subekti, Firli Reisya; Affandhy, Adhwa'a Kaylla
Jurnal Ilmiah Wahana Pendidikan Vol 11 No 1.D (2025): Jurnal Ilmiah Wahana Pendidikan 
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Demam tifoid merupakan penyakit yang sering terjadi di Indonesia, disebabkan oleh bakteri Salmonella typhi yang menyebar melalui jalur fecal-oral. Prevalensi demam tifoid di Indonesia mencapai 1,60%, dengan prevalensi tertinggi pada anak-anak berusia 5 hingga 14 tahun karena kebiasaan jajan sembarangandan kurangnya perhatian terhadap kebersihan diri . Pengobatan demam tifoid melibatkan pemberian antibiotik yang tepat dan perawatan suportif. Studi ini bertujuan untuk menganalisisefektivitas antibiotik dalam mengurangi durasi terapidemam tifoid, dengan fokus pada antibiotik seperticeftriaxone, cefotaxime, azithromycin, ciprofloxacin, kloramfenikol, dan tiamfenikol. Metode yang digunakan dalam penelitian initermasuk dalam jenis penelitian systematics literature review. Penelitian menunjukkan bahwa ceftriaxone lebih efektif dari pada kloramfenikol dalam mengatasi demam tifoid, dan kombinasi antibiotik seperti tiamfenikol dan ceftriaxone dapat mengurangi lama rawat inap. Azitromisin juga efektif untuk kasus tanpa komplikasi. Penggunaanantibiotik yang tepat penting untuk mengurangi case fatality rate. Terapi kombinasi dapat memperluas spektrumaktivitas antimikroba dan mencegah resistensi. Studi ini memberikan wawasan tentang pengobatan demam tifoiddengan antibiotik yang efektif, seperti ceftriaxone, azithromycin, dan kombinasi antibiotik tertentu. Pentingnya edukasi tentang kebersihan pribadi dan lingkungan juga disorot untuk mencegah penyebaran infeksi lebih lanjut. Dengan pemahaman yang lebih baiktentang efektivitas antibiotik dalam pengobatan demam tifoid, diharapkan dapat meningkatkan penanganan kasusdemam tifoid dan mengurangi dampak negatifnya.Kata kunci: Demam tifoid, Lama pengobatan, Terapi antibiotik, Efikasi obat, dan Efektivitas perbandingan
Review Artikel: Pengaruh Perbandingan Fase Gerak Dalam Analisis Senyawa Hidrokuinon Pada Sediaan Kosmetik Menggunakan Metode High Performance Liquid Chromatography (HPLC) Basmalah, Nur; Hariadi , Nayla Nur Azkia; Mulki , Munir Alinu
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.687

Abstract

Hydroquinone is a compound that is often used in cosmetic products because of its ability to brighten the skin by inhibiting melanin production. However, its use can cause dangerous side effects such as irritation, hyperpigmentation and the risk of cancer, so its use in cosmetics has been limited by BPOM. High Performance Liquid Chromatography (HPLC) is an analytical method commonly used to detect hydroquinone in cosmetic preparations because of its sensitivity and ability to separate compounds with high complexity. This article is a literature review which aims to determine the effect of mobile phase comparison on hydroquinone analysis using the HPLC method. The research results show that selecting the right mobile phase is very important to guarantee accurate, precise and efficient analysis results. The combination of a polarity-based mobile phase that matches the properties of hydroquinone provides good resolution, high sensitivity, and optimal retention time. This research is expected to provide guidance in optimizing the HPLC method for hydroquinone analysis, and is expected to support cosmetic safety monitoring.
Tinjauan Literatur: Pengaruh Parameter Metode Kromatografi Lapis Tipis untuk Identifikasi Kafein dalam Kopi Hariadi, Nayla Nur Azkia; Basmalah, Nur; Laprilski , Dewi Hanun; Azzahra , Khaerunisa; Mulki , Munir Alinu
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.683

Abstract

Background: The rising consumption of coffee in Indonesia necessitates reliable methods for caffeine analysis to ensure product quality and safety. Thin Layer Chromatography (TLC) is a simple, effective, and polarity-based technique widely used for the qualitative identification of compounds like caffeine in coffee. However, the results of TLC analysis are highly dependent on several methodological parameters. Objectives: This literature review aims to identify and analyze the critical parameters of the TLC method—including the mobile phase, stationary phase, visualization techniques, and sample preparation—that influence the effectiveness of caffeine identification in coffee. Methods: A systematic literature review was conducted using online databases (Google Scholar, PubMed, Semantic Scholar, and Crossref). Articles from the last ten years were selected based on inclusion and exclusion criteria, resulting in nine primary studies for in-depth analysis. Results: The review confirms that silica gel 60 F254 is the most effective stationary phase. The composition of the mobile phase is crucial; a mixture of dichloromethane:methanol (9.5:0.5) was found to be optimal for separating caffeine, yielding Rf values within the ideal range of 0.3–0.7. Visualization under UV light at 254 nm successfully detected caffeine as dark spots. Sample preparation techniques, particularly reflux and ultrasonic extraction, significantly enhanced extraction efficiency and detection sensitivity. Factors such as mobile phase stability, spotting technique, and sample matrix were also identified as key influencers on the chromatographic results. Conclusion: TLC is an efficient and cost-effective method for the qualitative identification of caffeine in coffee. Its success is determined by the optimization of critical parameters, primarily the mobile phase composition. While excellent for initial screening, TLC requires complementary techniques for precise quantitative analysis. Future work should focus on standardizing these parameters to improve the reproducibility and reliability of caffeine analysis using TLC.
Literature Review : Study of molecular mechanism level of NSAID class of drugs as COX-2 inhibitors Zakiyah, Wildani; Sukma Wibowo, Sepvia Putri; Elyyana, Nina; Nur Darmawan, Shiyami Aulia; Lestari, Sepiyani Ayu; Sa'diyyah, Nur; Malau, Jekmal; Mulki, Munir Alinu
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.745 KB)

Abstract

NSAIDs (Non-Steroid Anti-Inflammatory Drugs) are drugs that can treat pain and inflammation. The therapeutic effect of NSAIDs as anti-inflammatory analgesics is that they have the ability to inhibit the biosynthesis of prostaglandins which are pain mediators. This prostaglandin has a major role in inhibiting the COX enzyme (cyclooxygenase) in which COX has two isoforms, namely COX1 isoenzyme (non-selective) and COX2 isoenzyme (selective). Tricyclic COX-2 selective inhibitors work by blocking COX-2. COX-2 binds to PD-L1 via the PGE2 pathway and affects macrophages in suppressing myeloid. COX-2 has functions including producing reactive oxygen species that are responsible for DNA damage, activating substances that deviate from intracellular pathways such as the MAPK and PI3 K/AKT pathways, activating STAT3, inducing Bcl-2, and producing growth factors including growth factors. epidermal (EGF)) and fibroblast growth factor (FGF).
Review artikel: analisis faktor yang mempengaruhi kejadian pneumonia pada bayi dan balita Sholih, Mally Ghinan; Mulki, Munir Alinu; Julianti, Nurlia; Jannah, Roudotul; Indriyani, Yuni Lili
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.386

Abstract

Pneumonia is an infection of the lower respiratory tract which is the main cause of death in toddlers and children. Although there is a lot of information about risk factors for pneumonia, there is information that is not presented in detail and specifically. The purpose of this review article is to provide insight into the risk factors that cause pneumonia in babies and toddlers, making us more alert and aware of the importance of preventing and treating pneumonia, especially in babies and toddlers. The review method for this article is a literature review. The database comes from national and international journals via Google Scholar and PubMed databases published in the years 2013-2023. The results and discussion of this review include information about pneumonia, risk factors for pneumonia, and factors causing pneumonia in infants and toddlers. Based on the articles that have been reviewed, it shows that the factors that influence the incidence of pneumonia are exposure to cigarette smoke, LBW, nutritional status, gender, and history of exclusive breastfeeding. 
Aksi Mengenal dan Memilih Obat (AMMUBA) di Puskesmas Adiarsa Karawang Septiani, Dia; Mulki, Munir Alinu; Vriezka Mierza
LOSARI: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2023): Desember 2023
Publisher : LOSARI DIGITAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53860/losari.v5i2.177

Abstract

Drugs are an important element in health administration efforts, both preventive, promotive, curative, and rehabilitative. Errors in the selection and use of drugs can cause harm to public health and the environment. Educational actions have been carried out for the community in recognizing and choosing the right medicine, through health facilities at Puskesmas Adiarsa, Kabupaten Karawang. A total of 20 people were persuasively educated and given a pre-test questionnaire and an educational post-test questionnaire to measure the increase in knowledge and understanding. The results of this activity are known to people who are visiting the Puskesmas Adiarsa Karawang increased their understanding by 49% in recognizing and choosing drugs so that it can be said that educational activities to recognize and choose drugs are successful and people are smarter in using drugs.
Hubungan Tingkat Pengetahuan Swamedikasi Penyakit Ringan dengan Pengelolaan Limbah Obat di salah satu Pesantren di Karawang: The Relationship Between Knowledge of Self-Medication for Minor Illnesses and Drug Waste Management at an Islamic Boarding School in Karawang Iqbal Ramdhani Asa’af; Indah Laily Hilmi; Munir Alinu Mulki
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 6 No. 1 (2025): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v6i1.13134

Abstract

Self-medication or self-treatment is an attempt by a person to treat themselves by recognizing the symptoms or illnesses they are experiencing and choosing their own medicine. However, in reality, self-medication is not accompanied by good drug waste management. So this study aims to measure students' knowledge about self-medication and drug waste management at Insan Harapan Islamic Boarding School and analyze the relationship between students' self-medication knowledge and drug waste management. The approach used in this study is the Cross-Sectional method. The study population consisted of all high school students at Insan Harapan Islamic Boarding School in Karawang, with a sample of 187 students selected using non-probability sampling. Data were analyzed using the spearman rank test. The results showed that 60% of respondents had a high level of knowledge about self-medication for minor illnesses, while 71% demonstrated good practices in drug waste management. This study also found a significant relationship between students' knowledge of self-medication for minor illnesses and their practices in drug waste management. The correlation test shows a significance p-value test is 0.01, which is less than 0.05, so it can be concluded that there is a relationship between the level of knowledge of self-medication for minor illnesses and the management of drug waste at the Insan Harapan Karawang Islamic Boarding School. However, this relationship is low with a coefficient correlation value of 0.25. These findings highlight the importance of enhancing health education on self-medication and drug waste management, as well as developing policies to regulate drug waste management to prevent adverse environmental impacts. Keywords: Self-medication; Knowledge; Waste; Medicine.
ANTIOXIDANT ACTIVITY TEST OF BALAKACIDA LEAVES (Chromolaena odorata L) WITH DPPH (2,2-difenil-1-pikrilhidrazil) METHOD Elsya Martia; Munir Alinu Mulki; Lina Nurfadhila
Analit : Analytical and Environmental Chemistry Vol. 9, No. 01 April (2024) Analit : Analytical and Environmental Chemistry
Publisher : Jurusan Kimia FMIPA Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/analit.v9i01.170

Abstract

Balakacida leaves (Chromolaena odorata L) are plants known for their allelopathic properties, which can be utilized as natural herbicides. Empirically, they are used as wound healing agents, mouthwash, anti-diarrheal, antimicrobial, and anti-inflammatory medicines. The leaves are processed by squeezing them to extract their liquid, which is then applied to skin wounds for treatment (Marianne, 2014). Flavonoid components in balakacida leaves have antimicrobial effects. The focus of this research is to determine the IC50 value of balakacida leaves and characterize their antioxidant ability. Multi-step maceration using polarity-based solvents (n-hexane, ethyl acetate, and ethanol) is employed for extraction. The DPPH technique is utilized to evaluate antioxidant capacity. Phytochemical analysis has revealed active secondary metabolites with antioxidant properties in the plant, including tannins, flavonoids, alkaloids, and steroids. The IC50 values for n-hexane, ethyl acetate, and ethanol extracts are 35.58, 14.24, and 12.73 ppm respectively, indicating very high antioxidant activity. According to Fitrah (2017), crude balakacida leaf extract exhibits antioxidant effects. These effects are attributed to the high content of flavonoids, which possess antioxidant activity capable of inhibiting the oxidation process.  
Peningkatan Pemahaman Masyarakat Mengenai Penggunaan Antibiotik untuk Cegah Resistensi di Kampung Rawa Panjang Mulki, Munir Alinu; Sholih, Mally Ghinan; Utami, Marsah Rahmawati; Siboro, Dewi Pratiwi Purba
Kolaborasi Masyarakat Volume 1 Issue 1
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/kolmas0101210

Abstract

Antibiotics are substances or compounds that are either synthetically produced or naturally generated by microorganisms, especially fungi. They are used as inhibitors of other microorganisms. The use of antibiotics in humans is based on their minimal toxicity to the human body. Inaccurate and prolonged use of antibiotics can lead to the development of resistance. A step taken to minimize antibiotic resistance is the introduction of the 2023 PITIK (Penyuluhan Informasi Tentang Antibiotik) program. Thirty-three participants from the community around Kampung Rawa Panjang, Gang Pemuda, RT 01/RW 05, Kota Bekasi, attended this antibiotic education program. Education for the community was conducted using a cross-sectional approach and a questionnaire as an instrument. The results of questionnaire data analysis show that public understanding of the definition, how it works, side effects, how to purchase and how to use antibiotics correctly increased from 27.3% to 93.9%. Therefore, it can be concluded that this education program helps improve public awareness of the proper use of antibiotics.
Co-Authors Affandhy, Adhwa'a Kaylla Afifah Rusyda Sani Ain Luthfiannisa Akifah, Muthia Nur Aldila Divana Sarie Alfina Oktavianti Amanda Maharani Angel Novia Fransiska Anggi Ayu Pratama Anisa Amanda Putri Anisa Aula Rahma Anisa Fauziah Annisa Frastica Septi Aprillia, Cantika Arline Rahmadianti Kusumawardhani Asman Hitopik Asri Yuniar Aurora Fatimatuz Zahro Azzahra , Khaerunisa Basmalah, Nur Biandra Cinta Ramadhani Cantika Nurul Sa'adah Cantika Nurul Sa'adah Chalisya Vanya Advaita Chantiara Farida Makussy Muini Choerunnisa Choerunnisa Datu Muhammad Cordova Dia Septiani Diva Afiah Hanifa Irawan Dzaky Teguh Ramadhani Elsya Martia Elvira Julia Ariyanto Elyyana, Nina Elzandra Imola Vioniken Eriyanti Astika Esti Syahrin Faizal Auladi Rivianto Fathina Annajla Febry Nola Odhia Fikri Aldebaran Misbah Azizi Giga Anugerah Arsylrakhmatika Gun Gun Gumilar Gun Gun Gumilar Hadi Sudarjat Hanifah Nur Widodo Hariadi , Nayla Nur Azkia Hariadi, Nayla Nur Azkia Herdiana Verliani Hidayat, Sofianti Ibtisamah Haura Ihsan Alfiandri Indah Laily Hilmi Indah Laily Hilmi Indah Laily Hilmi Indah Laily Hilmi Indriyani, Yuni Lili Iqbal Ramdhani Asa’af Irene Virda Sakina Isyana S alsabila Izmi Haura Izmi Haura Syahida Jasmine Rahma Saputri Jekmal Malau Jekmal Malau Julianti, Nurlia Karlina Dwi Samratul Jannah Laprilski , Dewi Hanun Lestari Mahardika Urbaningrum Lestari, Sepiyani Ayu Lina Nurfadhila Madame Marselly Sebayang Maharani, Puteri Rahma Mally Ghinan Sholih Mally Ghinan Sholih Mally Ghinan Sholih Mally Ghinan Sholih Marsah Rahmawati Utami Marsah Rahmawati Utami Marsah Rahmawati Utami Martia, Elsya Meliana Sari Melisa Intan Barliana Mochamad Galuh Ryandha Moza Aulia Syifni Muhammad Fajri Maariz Muhammad Ja'far Ash Shidiq Muhammad Naufal Nurhadi Hidayat Muhammad Naufal Nurhadi Hidayat Muhammad Naufal Nurhadi Hidayat Muhammad Raka Tresna Mukarromah Dita Putri Mulidini Mulidini Mutia Desvi Putri Mutiara Alfiyah Najah Fatihatul Arifia Najla Yusiana Wahyudi Nanda Diva Meilani Nariyyah Fitriana Nariyyah Fitriana Nariyyah Fitriana Nissa Khalida Hanum Nolla Olipia Elva Megrian Nur Asyifa Rizkia Navisa Nur Darmawan, Shiyami Aulia Nur Komala Fitri Nurfadhila, Lina Nurfirah Mubarok Nurhadis, Nurhadis Nurlia Julianti Nurlita Dwi Putri Prihasti Nurlita Dwi Putri Prihasti Nurlita Dwiputri Prihasti Nurma Dwi Rahmawati Pratama, Reza Priscinya Christiana Debora Priscinya Christiana Debora Puteri Rahma Maharani Putri Setya Tyasna Putri Wahyu Primasti Putri Wulanbirru Rachel Noveriachristie Balapadang Rahma Amalia Ratu Siti Robiatul Awaliyah Rifa Nur Alia Rima Putri Ramadhani Riska Shafira Rizki Rava Dwi Putra Roudotul Jannah Roudotul Jannah Sa'adah, Cantika Nurul Sa'diyyah, Nur Saarah Hamidah Asmara Indratno Safira Rosyidah Salma Alviyah Salman Salman Salman Salman Salsabila Granadha Nibullah Salsabila Ramadani Saputro, M. Ramadhan Septiani, Dia Shafira Intan Anggraini Shalum Putriyani Shinta Puspa Dwiyanti Sholih, Mally Ghinan Siboro, Dewi Pratiwi Purba Siska Bela Safitri Siti Nafisa Siti Nur Istiqomah Siti Nuriah Siti Rohmah Siti Rosilfa Marisa Sofianti Hidayat Sophy Wulandari Sri Rahayu Subekti, Firli Reisya Sudarjat, Hadi Sukma Wibowo, Sepvia Putri Sulistiawati Sulistiawati Syelziva Yonda Atwita Syifa Khairunnisa TIANA MILANDA Tiara Cinta Amelia Tiara Cinta Amelia Tiara Nurayuni Tintia Rafika Putri Tiwi Ambarati Velieana Laurent Sanjaya Vina Luthfiana Hasna Vriezka Mierza Vriezka Mierza Vriezka Mierza Welly Windari Yesica Natalia Lawrence Yumareta Anggun Yuni Lili Indriyani Yuni Lili Indriyani Yuniar Fathil Ilmi Yuniar Fathil Ilmi Yuniar Fathil Ilmi Zahra Dwi Prameswari Zakiyah, Wildani Zhafira Aulia Hasanah Zuyyinna Alya Abbas