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All Journal Jurnal Kesehatan Acta Pharmaciae Indonesia : Acta Pharm Indo PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Sehat Mandiri INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Pendidikan dan Konseling Best Journal (Biology Education, Sains and Technology) Jurnal Integrasi Kesehatan dan Sains LOSARI: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Wahana Pendidikan Jurnal EduHealth Jurnal Kesehatan Innovative: Journal Of Social Science Research Journal of Sustainable Community Service Journal of Pharmaceutical and Sciences. Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Dedikasi Olahraga Dan Kesehatan Jurnal Adiguna Pengabdian Masyarakat Kolaborasi Masyarakat PharmaCine: Journal of Pharmacy, Medical and Health Science Analit: Analytical And Environmental Chemistry
Munir Alinu Mulki
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Singaperbangsa Karawang, Karawang, Jawa Barat, Indonesia.
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Veterinary Other

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Penyuluhan Hormon Paratiroid, Kalsitonin, dan Obat yang Bekerja pada Tulang di SMAN 1 Karawang Munir Alinu Mulki; Rizki Rava Dwi Putra; Jasmine Rahma Saputri; Siti Rosilfa Marisa; Ihsan Alfiandri
Jurnal Dorkes (Dedikasi Olahraga dan Kesehatan) Vol 1 No 2 (2023): DORKES Edisi September 2023
Publisher : Fakultas Ilmu Kesehatan UNSIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/dorkes.v1i2.10449

Abstract

Kalsium merupakan mineral yang paling penting bagi berbagai fungsi di dalam tubuh. Kelenjar paratiroid dan tiroid bertanggung jawab mengatur kadar kalsium dalam tubuh dengan cermat. Penyusunan jurnal ini ditujukan untuk mengamati pengetahuan siswa SMAN 1 Karawang terkait pengetahuan tentang hormon paratiroid, kalsitonin beserta obat yang bekerja pada tulang, karena berdasarkan survei yang telah dilakukan diketahui bahwa siswa-siswa SMAN 1 Karawang kurang memahami mengenai pengetahuan hormon paratiroid, kalsitonin beserta obatx yang bekerja pada tulang. Metode yang diterapkan adalah metode tes untuk menguji kemampuan responden berupa pemberian Pre-Test dan Post-Test, data tes tersebut diolah menggunakan aplikasi SPSS. Hasil Post-Test menggambarkan bahwa terdapat kenaikan nilai sebanyak 18,4% setelah dilakukan kegiatan penyampaian materi. Hal ini dapat diketahui dari nilai hasil rata-rata Pre-test 5,58 dan setelah dilakukan penyuluhan terdapat peningkatan nilai rata-rata Post-test menjadi 7,42. Dengan demikian, dapat disimpulkan bahwa penyuluhan kesehatan memiliki dampak signifikan terhadap pengetahuan siswa-siswi di SMAN 1 Karawang mengenai hormon paratiroid, kalsitonin beserta obat yang bekerja pada tulang.
Perbandingan Efektivitas Antibiotik Terhadap Durasi Terapi Demam Tifoid Sholih, Mally Ghinan; Mulki, Munir Alinu; Nurhadis, Nurhadis; Akifah, Muthia Nur; Aprillia, Cantika; Maharani, Puteri Rahma; Subekti, Firli Reisya; Affandhy, Adhwa'a Kaylla
Jurnal Ilmiah Wahana Pendidikan Vol 11 No 1.D (2025): Jurnal Ilmiah Wahana Pendidikan 
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Demam tifoid merupakan penyakit yang sering terjadi di Indonesia, disebabkan oleh bakteri Salmonella typhi yang menyebar melalui jalur fecal-oral. Prevalensi demam tifoid di Indonesia mencapai 1,60%, dengan prevalensi tertinggi pada anak-anak berusia 5 hingga 14 tahun karena kebiasaan jajan sembarangandan kurangnya perhatian terhadap kebersihan diri . Pengobatan demam tifoid melibatkan pemberian antibiotik yang tepat dan perawatan suportif. Studi ini bertujuan untuk menganalisisefektivitas antibiotik dalam mengurangi durasi terapidemam tifoid, dengan fokus pada antibiotik seperticeftriaxone, cefotaxime, azithromycin, ciprofloxacin, kloramfenikol, dan tiamfenikol. Metode yang digunakan dalam penelitian initermasuk dalam jenis penelitian systematics literature review. Penelitian menunjukkan bahwa ceftriaxone lebih efektif dari pada kloramfenikol dalam mengatasi demam tifoid, dan kombinasi antibiotik seperti tiamfenikol dan ceftriaxone dapat mengurangi lama rawat inap. Azitromisin juga efektif untuk kasus tanpa komplikasi. Penggunaanantibiotik yang tepat penting untuk mengurangi case fatality rate. Terapi kombinasi dapat memperluas spektrumaktivitas antimikroba dan mencegah resistensi. Studi ini memberikan wawasan tentang pengobatan demam tifoiddengan antibiotik yang efektif, seperti ceftriaxone, azithromycin, dan kombinasi antibiotik tertentu. Pentingnya edukasi tentang kebersihan pribadi dan lingkungan juga disorot untuk mencegah penyebaran infeksi lebih lanjut. Dengan pemahaman yang lebih baiktentang efektivitas antibiotik dalam pengobatan demam tifoid, diharapkan dapat meningkatkan penanganan kasusdemam tifoid dan mengurangi dampak negatifnya.Kata kunci: Demam tifoid, Lama pengobatan, Terapi antibiotik, Efikasi obat, dan Efektivitas perbandingan
Review Artikel: Pengaruh Perbandingan Fase Gerak Dalam Analisis Senyawa Hidrokuinon Pada Sediaan Kosmetik Menggunakan Metode High Performance Liquid Chromatography (HPLC) Basmalah, Nur; Hariadi , Nayla Nur Azkia; Mulki , Munir Alinu
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.687

Abstract

Hydroquinone is a compound that is often used in cosmetic products because of its ability to brighten the skin by inhibiting melanin production. However, its use can cause dangerous side effects such as irritation, hyperpigmentation and the risk of cancer, so its use in cosmetics has been limited by BPOM. High Performance Liquid Chromatography (HPLC) is an analytical method commonly used to detect hydroquinone in cosmetic preparations because of its sensitivity and ability to separate compounds with high complexity. This article is a literature review which aims to determine the effect of mobile phase comparison on hydroquinone analysis using the HPLC method. The research results show that selecting the right mobile phase is very important to guarantee accurate, precise and efficient analysis results. The combination of a polarity-based mobile phase that matches the properties of hydroquinone provides good resolution, high sensitivity, and optimal retention time. This research is expected to provide guidance in optimizing the HPLC method for hydroquinone analysis, and is expected to support cosmetic safety monitoring.
Tinjauan Literatur: Pengaruh Parameter Metode Kromatografi Lapis Tipis untuk Identifikasi Kafein dalam Kopi Hariadi, Nayla Nur Azkia; Basmalah, Nur; Laprilski , Dewi Hanun; Azzahra , Khaerunisa; Mulki , Munir Alinu
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.683

Abstract

Background: The rising consumption of coffee in Indonesia necessitates reliable methods for caffeine analysis to ensure product quality and safety. Thin Layer Chromatography (TLC) is a simple, effective, and polarity-based technique widely used for the qualitative identification of compounds like caffeine in coffee. However, the results of TLC analysis are highly dependent on several methodological parameters. Objectives: This literature review aims to identify and analyze the critical parameters of the TLC method—including the mobile phase, stationary phase, visualization techniques, and sample preparation—that influence the effectiveness of caffeine identification in coffee. Methods: A systematic literature review was conducted using online databases (Google Scholar, PubMed, Semantic Scholar, and Crossref). Articles from the last ten years were selected based on inclusion and exclusion criteria, resulting in nine primary studies for in-depth analysis. Results: The review confirms that silica gel 60 F254 is the most effective stationary phase. The composition of the mobile phase is crucial; a mixture of dichloromethane:methanol (9.5:0.5) was found to be optimal for separating caffeine, yielding Rf values within the ideal range of 0.3–0.7. Visualization under UV light at 254 nm successfully detected caffeine as dark spots. Sample preparation techniques, particularly reflux and ultrasonic extraction, significantly enhanced extraction efficiency and detection sensitivity. Factors such as mobile phase stability, spotting technique, and sample matrix were also identified as key influencers on the chromatographic results. Conclusion: TLC is an efficient and cost-effective method for the qualitative identification of caffeine in coffee. Its success is determined by the optimization of critical parameters, primarily the mobile phase composition. While excellent for initial screening, TLC requires complementary techniques for precise quantitative analysis. Future work should focus on standardizing these parameters to improve the reproducibility and reliability of caffeine analysis using TLC.
Literature Review : Study of molecular mechanism level of NSAID class of drugs as COX-2 inhibitors Zakiyah, Wildani; Sukma Wibowo, Sepvia Putri; Elyyana, Nina; Nur Darmawan, Shiyami Aulia; Lestari, Sepiyani Ayu; Sa'diyyah, Nur; Malau, Jekmal; Mulki, Munir Alinu
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.745 KB)

Abstract

NSAIDs (Non-Steroid Anti-Inflammatory Drugs) are drugs that can treat pain and inflammation. The therapeutic effect of NSAIDs as anti-inflammatory analgesics is that they have the ability to inhibit the biosynthesis of prostaglandins which are pain mediators. This prostaglandin has a major role in inhibiting the COX enzyme (cyclooxygenase) in which COX has two isoforms, namely COX1 isoenzyme (non-selective) and COX2 isoenzyme (selective). Tricyclic COX-2 selective inhibitors work by blocking COX-2. COX-2 binds to PD-L1 via the PGE2 pathway and affects macrophages in suppressing myeloid. COX-2 has functions including producing reactive oxygen species that are responsible for DNA damage, activating substances that deviate from intracellular pathways such as the MAPK and PI3 K/AKT pathways, activating STAT3, inducing Bcl-2, and producing growth factors including growth factors. epidermal (EGF)) and fibroblast growth factor (FGF).
Review artikel: analisis faktor yang mempengaruhi kejadian pneumonia pada bayi dan balita Sholih, Mally Ghinan; Mulki, Munir Alinu; Julianti, Nurlia; Jannah, Roudotul; Indriyani, Yuni Lili
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.386

Abstract

Pneumonia is an infection of the lower respiratory tract which is the main cause of death in toddlers and children. Although there is a lot of information about risk factors for pneumonia, there is information that is not presented in detail and specifically. The purpose of this review article is to provide insight into the risk factors that cause pneumonia in babies and toddlers, making us more alert and aware of the importance of preventing and treating pneumonia, especially in babies and toddlers. The review method for this article is a literature review. The database comes from national and international journals via Google Scholar and PubMed databases published in the years 2013-2023. The results and discussion of this review include information about pneumonia, risk factors for pneumonia, and factors causing pneumonia in infants and toddlers. Based on the articles that have been reviewed, it shows that the factors that influence the incidence of pneumonia are exposure to cigarette smoke, LBW, nutritional status, gender, and history of exclusive breastfeeding. 
Aksi Mengenal dan Memilih Obat (AMMUBA) di Puskesmas Adiarsa Karawang Septiani, Dia; Mulki, Munir Alinu; Vriezka Mierza
LOSARI: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2023): Desember 2023
Publisher : LOSARI DIGITAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53860/losari.v5i2.177

Abstract

Drugs are an important element in health administration efforts, both preventive, promotive, curative, and rehabilitative. Errors in the selection and use of drugs can cause harm to public health and the environment. Educational actions have been carried out for the community in recognizing and choosing the right medicine, through health facilities at Puskesmas Adiarsa, Kabupaten Karawang. A total of 20 people were persuasively educated and given a pre-test questionnaire and an educational post-test questionnaire to measure the increase in knowledge and understanding. The results of this activity are known to people who are visiting the Puskesmas Adiarsa Karawang increased their understanding by 49% in recognizing and choosing drugs so that it can be said that educational activities to recognize and choose drugs are successful and people are smarter in using drugs.
Review Artikel: Karakterisasi Dan Uji Efektivitas Antikanker Nanopartikel Emas (AuNPs) Dan Nanopartikel Perak (AgNPs) Dengan Ekstrak Kunyit (Curcuma spp.) Sebagai Bioreduktor Haura, Izmi; Mulki, Munir Alinu
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.678

Abstract

Cancer is one of the leading causes of death in the world with major challenges in the form of therapeutic side effects, poor selectivity, and drug resistance. Nanotechnology, particularly the use of gold (AuNPs) and silver (AgNPs) nanoparticles, offers a promising alternative to improve the effectiveness of cancer therapy. This article reviews recent developments in the synthesis of AuNPs and AgNPs using turmeric as a natural, environmentally friendly bioreductor. Characterization of nanoparticles through UV-Vis, TEM, SEM, and FT-IR methods showed particle sizes ranging from 1-100 nm, spherical or hexagonal morphology, and the presence of functional groups such as -OH and C=O that support stability and bioactivity. Anticancer studies show that these nanoparticles are effective against various types of cancer cells, including breast (MCF-7, MDA-MB-231), lung (A549, NCI-H661, NCI-H1975, NCI-H1573, NCI-H1563), cervical (HeLa), and epithelial (Hep-2) cancers.
Aktivitas Antidiabetes Infusa Buah Mengkudu (Morinda Citrifolia L.) pada Mencit Jantan terinduksi Aloksan Mulki, Munir Alinu; Amelia , Tiara Cinta
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1247

Abstract

Noni (Morinda citrifolia L.) is traditionally consumed for diabetes, yet in vivo evidence for water-based infusion remains limited. This study aimed to evaluate the antihyperglycemic effect of a standardized noni fruit infusion in alloxan-induced male mice. Dried fruit simplicia were quality-controlled according to the Indonesian Herbal Pharmacopoeia. Mice were induced with alloxan (140 mg/kg, i.p.) and randomized (n=5/group) to vehicle (0.5% Na-CMC), metformin (1.3 mg/20 g BW), or noni infusion at low (103), normal (123), or high (144 mg/20 g BW) for 21 days in two divided doses per day. Fasting blood glucose was measured at baseline, day 0, and days 7, 14, and 21. Paired t-tests assessed within-group changes, while between-group comparisons used one-way ANOVA with Levene’s test (Tukey HSD) and Welch ANOVA as sensitivity analysis. Phytochemical screening indicated alkaloids, saponins, triterpenoids, and flavonoids. All groups showed significant reductions from day 0 to day 21 (p<0.05). From day 0 to day 14, the normal-dose infusion decreased glucose by 45.7% (172.8 to 93.8 mg/dL), compared with 33.3% for metformin (134.0 to 89.4 mg/dL). By day 21, reductions were 48.3–49.6% in the normal/high-dose infusion groups and 36.4% with metformin. Between-group differences were evident at days 7 and 14 but not at day 21 (p>0.05). Standardized noni infusion exhibits antihyperglycemic activity in the alloxan model; confirmation of mechanisms, additional metabolic endpoints, and subchronic safety evaluation are required before clinical relevance can be inferred.
GERAKAN PEDULI KEBERSIHAN MANDIRI (KALI BERSAMA) Hilmi, Indah Laily; Salman, Salman; Sudarjat, Hadi; Gumilar, Gun Gun; Mulki, Munir Alinu
JOURNAL OF SUSTAINABLE COMMUNITY SERVICE Vol. 3 No. 1 (2022): DECEMBER
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/jscs.v3i1.636

Abstract

The Gerakan Peduli Kebersihan Mandiri (Kali Bersama) is an initiative carried out by the Pharmacy students of Singaperbangsa University Karawang with the aim of raising awareness among teenagers in Citra Kebun Mas Housing, Karawang about clean and healthy living behaviors, especially handwashing with soap. This research aims to improve teenagers' understanding of Clean and Healthy Living Behavior (PHBS) and proper handwashing techniques. The method used in this research is counseling, which includes education on the importance of PHBS and demonstration of proper handwashing techniques. The questionnaire results conducted after the counseling show that the majority of teenagers are aware of PHBS and apply it in their daily lives, but there is still a gap between knowledge and PHBS practices. Based on these results, it is recommended to adjust the timing of activities, involve faculty leaders, and provide adequate facilities for the handwashing program with soap in future activities.
Co-Authors Affandhy, Adhwa'a Kaylla Afifah Rusyda Sani Ain Luthfiannisa Akifah, Muthia Nur Aldila Divana Sarie Alfina Oktavianti Amanda Maharani Amelia , Tiara Cinta Angel Novia Fransiska Anggi Ayu Pratama Anisa Amanda Putri Anisa Aula Rahma Anisa Fauziah Annisa Frastica Septi Aprillia, Cantika Arline Rahmadianti Kusumawardhani Asman Hitopik Asri Yuniar Aurora Fatimatuz Zahro Azzahra , Khaerunisa Basmalah, Nur Biandra Cinta Ramadhani Cantika Nurul Sa&#039;adah Cantika Nurul Sa'adah Chalisya Vanya Advaita Choerunnisa Choerunnisa Datu Muhammad Cordova Dia Septiani Diva Afiah Hanifa Irawan Dzaky Teguh Ramadhani Elsya Martia Elvira Julia Ariyanto Elyyana, Nina Elzandra Imola Vioniken Eriyanti Astika Esti Syahrin Faizal Auladi Rivianto Fathina Annajla Febry Nola Odhia Fikri Aldebaran Misbah Azizi Fitriana, Nariyyah Giga Anugerah Arsylrakhmatika Gun Gun Gumilar Hanifah Nur Widodo Hariadi , Nayla Nur Azkia Hariadi, Nayla Nur Azkia Haura, Izmi Herdiana Verliani Hidayat, Sofianti Ibtisamah Haura Ihsan Alfiandri Ilmi, Yuniar Fathil Indah Laily Hilmi Indah Laily Hilmi Indah Laily Hilmi Indriyani, Yuni Lili Iqbal Ramdhani Asa’af Irene Virda Sakina Isyana S alsabila Izmi Haura Syahida Jasmine Rahma Saputri Jekmal Malau Jekmal Malau Julianti, Nurlia Karlina Dwi Samratul Jannah Laprilski , Dewi Hanun Lestari Mahardika Urbaningrum Lestari, Sepiyani Ayu Lina Nurfadhila Madame Marselly Sebayang Maharani, Puteri Rahma Mally Ghinan Sholih Mally Ghinan Sholih Mally Ghinan Sholih Mally Ghinan Sholih Marsah Rahmawati Utami Marsah Rahmawati Utami Martia, Elsya Meliana Sari Melisa Intan Barliana Mochamad Galuh Ryandha Moza Aulia Syifni Muhammad Fajri Maariz Muhammad Ja'far Ash Shidiq Muhammad Naufal Nurhadi Hidayat Muhammad Naufal Nurhadi Hidayat Muhammad Naufal Nurhadi Hidayat Muhammad Raka Tresna Mukarromah Dita Putri Mulidini Mulidini Mutia Desvi Putri Mutiara Alfiyah Najah Fatihatul Arifia Najla Yusiana Wahyudi Nanda Diva Meilani Nariyyah Fitriana Nariyyah Fitriana Nissa Khalida Hanum Nolla Olipia Elva Megrian Nur Asyifa Rizkia Navisa Nur Darmawan, Shiyami Aulia Nur Komala Fitri Nurfadhila, Lina Nurfirah Mubarok Nurhadis, Nurhadis Nurlia Julianti Nurlita Dwi Putri Prihasti Nurlita Dwi Putri Prihasti Nurlita Dwiputri Prihasti Nurma Dwi Rahmawati Pratama, Reza Priscinya Christiana Debora Priscinya Christiana Debora Puteri Rahma Maharani Putri Setya Tyasna Putri Wahyu Primasti Putri Wulanbirru Rachel Noveriachristie Balapadang Rahma Amalia Ratu Siti Robiatul Awaliyah Rifa Nur Alia Rima Putri Ramadhani Riska Shafira Rizki Rava Dwi Putra Roudotul Jannah Roudotul Jannah Sa'adah, Cantika Nurul Sa'diyyah, Nur Saarah Hamidah Asmara Indratno Safira Rosyidah Salma Alviyah Salman Salman Salsabila Granadha Nibullah Salsabila Ramadani Saputro, M. Ramadhan Septiani, Dia Shafira Intan Anggraini Shalum Putriyani Shinta Puspa Dwiyanti Sholih, Mally Ghinan Siboro, Dewi Pratiwi Purba Siska Bela Safitri Siti Nafisa Siti Nur Istiqomah Siti Nuriah Siti Rohmah Siti Rosilfa Marisa Sofianti Hidayat Sophy Wulandari Sri Rahayu Subekti, Firli Reisya Sudarjat, Hadi Sukma Wibowo, Sepvia Putri Sulistiawati Sulistiawati Syelziva Yonda Atwita Syifa Khairunnisa TIANA MILANDA Tiara Cinta Amelia Tiara Nurayuni Tintia Rafika Putri Tiwi Ambarati Velieana Laurent Sanjaya Vina Luthfiana Hasna Vriezka Mierza Vriezka Mierza Vriezka Mierza Welly Windari Yesica Natalia Lawrence Yumareta Anggun Yuni Lili Indriyani Yuni Lili Indriyani Yuniar Fathil Ilmi Yuniar Fathil Ilmi Zahra Dwi Prameswari Zakiyah, Wildani Zhafira Aulia Hasanah Zuyyinna Alya Abbas