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All Journal Jurnal Kesehatan Jurnal Sehat Mandiri INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Pendidikan dan Konseling Jurnal Integrasi Kesehatan dan Sains LOSARI: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Wahana Pendidikan Jurnal EduHealth Jurnal Kesehatan Innovative: Journal Of Social Science Research Journal of Sustainable Community Service Analit: Analytical and Environmental Chemistry Journal of Pharmaceutical and Sciences. Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Dedikasi Olahraga Dan Kesehatan Analit: Analytical And Environmental Chemistry
Munir Alinu Mulki
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Singaperbangsa Karawang, Karawang, Jawa Barat, Indonesia.
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Perbandingan Efektivitas dan Keamanan Obat Flutikason dan Amoksisilin dalam Mengatasi Sinusitis Akut pada Anak-Anak: Sebuah Tinjauan Sistematik Mini Munir Alinu Mulki; Eriyanti Astika; Sulistiawati Sulistiawati; Aldila Divana Sarie; Anisa Aula Rahma; Fikri Aldebaran Misbah Azizi; Karlina Dwi Samratul Jannah
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.713 KB) | DOI: 10.36490/journal-jps.com.v6i2.131

Abstract

Acute sinusitis (AS) can be defined as inflammation of the nose due to infection of the preanal sinus. Sinusitis is a common condition that occurs in children. Children experience an average of 6-8 colds per year with 0.5-5% developing acute sinusitis infection. Nasal corticosteroid drugs that are often used for sinusitis therapy are fluticasone. Not only that, antibiotic class drugs can also be used for the treatment of acute sinusitis, one of which is amoxicillin. The purpose of making this systematic review is to determine the effectiveness and combination of fluticasone and amoxicillin drugs in dealing with acute sinusitis treatment problems. The literature search was conducted electronically at PUBMED and was in accordance with the protocol made by PRISMA in conducting this systematic review. The literature search was conducted electronically for articles published in the last 10 years (from January 2013 to May 2023) and specific keywords 1. "acute sinusitis", OR 2. "fluticasone", OR 3. "amoxicillin", AND 4. "children" were used in the search. Inclusion criteria included experimental study design (randomized controlled trial). Articles were excluded according to case-control, cohort or qualitative study types. The data to be retrieved were the study population, type of intervention performed, study design, control variables, as well as the conclusions of the study. The article found 22 journals in the search strategy. In the end, there were 3 journals that met the eligibility criteria and were included in this systematic review. The three studies explained that the combination of fluticasone and amoxicillin had a more effective effect than monotherapy.
TINJAUAN LITERATUR TOKSISITAS METOTREKSAT SEBAGAI ANTIRHEUMATOID ARTHRITIS Nanda Diva Meilani; Munir Alinu Mulki; Elzandra Imola Vioniken; Siska Bela Safitri; Siti Nur Istiqomah; Meliana Sari; Syelziva Yonda Atwita
Jurnal Ilmiah Wahana Pendidikan Vol 9 No 14 (2023): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.8176493

Abstract

Rheumatoid Arthritis (RA) adalah penyakit autoimun dengan peradangan kronis pada sendi yang menyebabkan kerusakan sendi dan deformitas. Pengobatan RA melibatkan penggunaan obat-obatan seperti metotreksat (MTX), yang memiliki efek anti-inflamasi dan anti-proliferatif. Namun, penggunaan MTX dapat menyebabkan toksisitas dan efek samping yang dapat mempengaruhi keberhasilan terapi. Penelitian ini bertujuan untuk melakukan tinjauan literatur tentang toksisitas MTX sebagai pengobatan RA. Pencarian studi literatur dilakukan menggunakan Google Scholar melalui software Publish or Perish versi 8 dengan kata kunci "toksisitas metotreksat," "rheumatoid arthritis," dan "antirheumatoid arthritis." Studi literatur yang relevan dipilih berdasarkan judul dan metode yang digunakan dengan kriteria inklusi dan eksklusi pada jenis studi literatur, tahun terbit dan bidangnya. Studi literatur menunjukkan bahwa penggunaan MTX dalam pengobatan RA dapat menghasilkan efek terapeutik yang signifikan, tetapi juga dapat menyebabkan toksisitas. Toksisitas yang dapat terjadi termasuk supresi sumsum tulang, toksisitas paru, toksisitas ginjal, toksisitas hematologis, dan meningkatkan risiko infeksi. Hepatotoksisitas juga merupakan efek samping umum yang terkait dengan penggunaan MTX. Penggunaan MTX sebagai pengobatan RA efektif dalam mengurangi gejala dan mencegah kerusakan sendi. Namun, toksisitas dan efek sampingnya harus dipantau dengan baik. Pengetahuan tentang toksisitas MTX membantu dalam pemantauan dan manajemen yang tepat selama pengobatan RA.
Resistensi Obat Aspirin Terhadap Pasien Penyakit Jantung Koroner: Sebuah Literature Review Mally Ghinan Sholih; Munir Alinu Mulki; Ain Luthfiannisa; Esti Syahrin; Moza Aulia Syifni; Muhammad Naufal Nurhadi Hidayat; Safira Rosyidah; Salma Alviyah; Muhammad Raka Tresna
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.167

Abstract

In Indonesia, coronary heart disease is the largest contributor to mortality with a prevalence related to cardiovascular disease. Using drugs from a combination of fibrinolytics, anticoagulants, and antiplatelets can overcome acute coronary heart disease. The most commonly used therapy is the antiplatelet class in the form of aspirin as a treatment for the management of cardiovascular disease and its prevention. However, several studies have stated that aspirin is a conventional antiplatelet which sometimes has the potential to cause failure and is ineffective for the treatment of coronary heart disease, so that it can be said to be aspirin resistance. Article writing method review This study uses scientific literature. The steps taken begin with collecting various journal references through the database PubMed Identifier (PMID), google schoolar, and science direct within the last 10 years (2013-2023). The keyword in the literature search is aspirin resistance, aspirin resistance coronary disease, and aspirin coronary heart diseases. Based on the results of reviews that have been reviewed, it shows that there are resistance mechanisms and factors that influence aspirin resistance in coronary heart disease patients.
Review jurnal: pola perbandingan pengobatan farmakologi penderita dispepsia di beberapa rumah sakit Mally Ghinan Sholih; Munir Alinu Mulki; Sophy Wulandari; Putri Wahyu Primasti; Giga Anugerah Arsylrakhmatika; Nurlita Dwi Putri Prihasti; Amanda Maharani; Roudotul Jannah
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.170

Abstract

Dyspepsia is a common complaint often found in the community and among patients who come to clinical practice. Symptoms of dyspepsia include abdominal discomfort, nausea, vomiting, burning, bloating in the upper digestive tract, early satiety, fullness after eating, and belching. This literature review compared prescription patterns in dyspepsia patients from several hospitals. The research method began with a literature search through the PubMed and Google Scholar databases within the specified year range and using the keywords dyspepsia, pattern, treatment, and drug. The conclusion is that there are many uses for generic drugs and different types of drugs in treating patients with dyspepsia. Factors influencing the management of dyspepsia in inpatients include gender, reported clinical symptoms, class of antiulcer therapy, differences in the number of drugs, and drug dosage forms.  
Review artikel: efektivitas penggunaan fototerapi terhadap rinitis alergi pada ibu hamil Mally Ghinan Sholih; Munir Alinu Mulki; Annisa Frastica Septi; Muhammad Ja'far Ash Shidiq; Nariyyah Fitriana; Shalum Putriyani; Yuni Lili Indriyani; Yuniar Fathil Ilmi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.171

Abstract

Rhinitis is an inflammation of the mucous membrane of the nose that affects millions of people worldwide. Although there has been much research and development related to the management of rhinitis, there are still challenges in achieving effective treatment and optimal symptom control. The purpose of writing this article is to achieve effective treatment and optimal control of rhinitis symptoms. The writing method used is literature review by collecting primary references from international journals published in the last 10 years (2013-2023). Referrals are selected through the pubMed database with relevant keywords.  The results and discussion of this study include information on allergic rhinitis, rhinitis of pregnancy, hormonal changes during pregnancy, and commonly used medications. In the treatment of gestational rhinitis, the use of phototherapy can be the right choice. Based on articles that have been reviewed, it shows that treatment with phototherapy is more effective in overcoming the symptoms of allergic rhinitis. Phototherapy has a good effect on immunosuppressants and immunomodulators that can suppress the body's immune activity and also relieve inflammation.  
Perbandingan Efektivitas Dan Keamanan Obat Parasetamol Dan Topikal Analgesik Untuk Pasien Osteoarthritis Munir Alinu Mulki; Nurlia Julianti; Aurora Fatimatuz Zahro; Fathina Annajla; Choerunnisa Choerunnisa; Riska Shafira; Najah Fatihatul Arifia
Innovative: Journal Of Social Science Research Vol. 3 No. 3 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v3i3.2886

Abstract

Osteoarthritis (OA) merupakan penyakit rematik yang paling umum dialami oleh lansia dan berkaitan dengan risiko kematian paling besar daripada populasi umum. Parasetamol umumnya direkomendasikan sebagai analgesik pilihan pertama pada nyeri osteoarthritis. Selain itu, Obat antiinflamasi nonsteroid topikal (NSAID) juga memiliki efikasi dapat mengurangi nyeri pada osteoarthritis tanpa memberikan efek samping yang besar. Penulisan ini bertujuan untuk mengetahui perbandingan efektivitas dan keamanan obat parasetamol dan topikal NSAID untuk pasien osteoarthritis. Penulisan ini menggunakan metode review artikel yang dilakukan melalui penelusuran dari database Pubmed. Adapun kriteria artikel yang digunakan sebagai bahan untuk review artikel adalah artikel yang bukan merupakan publikasi review artikel dan bukan merupakan publikasi sistematik review dalam rentang 10 tahun terakhir menggunakan kata kunci (osteoarthritis) AND (paracetamol) AND (topical NSAID) NOT (review[publication type]) dan didapatkan sebanyak 16 artikel. Berdasarkan hasil yang diperoleh diketahui bahwa NSAID topikal memiliki profil keamanan yang lebih baik karena penyerapan sistemik yang lebih rendah, efek samping yang lebih kecil, efek terapeutik yang lebih cepat dan efektif dibandingkan dengan obat parasetamol.
VALIDASI METODE ANALISIS TIMBAL(II) PADA KERANG HIJAU MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS DERIVATISASI Cantika Nurul Sa'adah; Marsah Rahmawati Utami; Munir Alinu Mulki
Analit: Analytical and Environmental Chemistry Vol 8, No 2 (2023): ANALIT: ANALYTICAL AND ENVIRONMENTAL CHEMISTRY
Publisher : Universitas Lampung Jl. Prof. Dr. Sumatri Brojonegoro No.1 Bandar Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/aec.v8i2.2023.p53-62

Abstract

ABSTRAK Cemaran logam timbal berbahaya bagi lingkungan perairan maupun organismenya. Kerang hijau (Perna viridis L.) merupakan pilihan makanan yang enak, murah dan banyak dikonsumsi oleh masyarakat. Tujuan dari penelitian ini adalah untuk memvalidasi metode spektrofotometri UV-Vis derivatisasi analisis kadar timbal pada kerang hijau. Preparasi sampel kerang hijau menggunakan metode destruksi basah dengan pelarut HNO3 5M. Pb2+ direaksikan dengan larutan ditizon 0,005% dalam suasana basa terbentuk warna merah. Spektrofotometer UV-Vis digunakan untuk mengukur kompleks Pb-ditizonat pada panjang gelombang maksimum 515 nm. Nilai parameter validasi meliputi linearitas dengan persamaan regresi linear y = 0,5509x + 0,1114 dengan nilai r2 = 0,9959; Presisi didapatkan %RSD 0,130758%; LOD 0,088 ppm; LOQ 0,269 ppm. Akurasi diperoleh dengan %recovery 82,538%; dan spesifitas yang memiliki kesesuaian bentuk spektrum yang baik. Parameter validasi metode telah memenuhi persyaratan dan dapat diaplikasikan untuk pengujian kadar logam timbal pada kerang hijau. Kata kunci: validasi metode, logam timbal, kerang hijau, spektrofotometri UV-Vis. ABSTRACT Lead metal contamination is harmful to the aquatic environment and its organisms. Green mussel (Perna viridis L.) is is a delicious, cheap food choice and is widely consumed by the public. The aim of this study was to validate the UV-Vis spectrophotometric method derivatized for the analysis of lead levels in green mussels. Green mussel samples were prepared using the wet destruction method with 5M HNO3 solvent. Pb2+ reacted with 0,005% dithizone solution in alkaline conditions to form a red color. UV-Vis spectrophotometer was used to measure the Pb-dithizonate complex at a maximum wavelength of 515 nm. Validation parameter values include linearity with a linear regression equation y = 0,5509x + 0,1114 with a value of r2 = 0,9959; Precision obtained %RSD 0.130758%; LOD 0,088 ppm; LOQ 0,269 ppm. Accuracy is obtained with %recovery 82,538%; and specificity that has a good match of the shape of the spectrum. The method validation parameters have met the requirements and can be applied to test the levels of lead metal in green mussels. Keywords: method validation, lead metal, green mussels, UV-Vis spectrophotometry.
Review Jurnal : Faktor Pengaruh Hubungan Gagal Ginjal Akut Dan Covid-19 Mally Ghinan Sholih; Munir Alinu Mulki; Asman Hitopik; Ibtisamah Haura; Madame Marselly Sebayang; Nurfirah Mubarok; Rachel Noveriachristie Balapadang; Rima Putri Ramadhani; Rifa Nur Alia
Jurnal Ilmiah Wahana Pendidikan Vol 9 No 16 (2023): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.8248782

Abstract

COVID-19 is a disease caused by infection with the SARS-CoV-2 virus and has become a global pandemic outbreak because it is highly contagious and causes severe infections of the respiratory system. The SARS-CoV-2 virus causes infection primarily in the lungs and upper respiratory tract but can also infect other organs such as the brain, kidneys, intestines and liver. During the pandemic, many serious complications from COVID-19 were reported and one of them was acute kidney failure. Acute kidney failure is a condition where kidney dysfunction occurs quickly and suddenly. This study aims to investigate the factors that influence the relationship between acute kidney failure and COVID-19 infection. This research method begins with a literature search through the PubMed Identifier (PMID) database within a predetermined range of years and using the keywords pathophysiology, COVID-19, and acute kidney failure. The results of the review show that there are several factors that play a role in influencing the relationship between acute kidney failure and COVID-19 infection. Kidney damage in COVID-19 patients can occur due to a direct attack from the SARS-CoV-2 virus, the occurrence of a cytokine storm, or an indirect attack which can be caused by nephrotoxin exposure due to medical care given to the patient, secondary infection, or other factors. such as elderly and chronically ill patients. Based on the findings, it is known that there are risk factors, pathophysiological mechanisms, and patient medical care that can influence the relationship between acute kidney failure and COVID-19 infection. From the results of this analysis, it is hoped that the findings obtained can serve as a basis and guideline in the management of acute kidney failure as a complication of COVID-19.
GERAKAN PEDULI KEBERSIHAN MANDIRI (KALI BERSAMA) Hilmi, Indah Laily; Salman, Salman; Sudarjat, Hadi; Gumilar, Gun Gun; Mulki, Munir Alinu
JOURNAL OF SUSTAINABLE COMMUNITY SERVICE Vol. 3 No. 1 (2022): DECEMBER
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/jscs.v3i1.636

Abstract

The Gerakan Peduli Kebersihan Mandiri (Kali Bersama) is an initiative carried out by the Pharmacy students of Singaperbangsa University Karawang with the aim of raising awareness among teenagers in Citra Kebun Mas Housing, Karawang about clean and healthy living behaviors, especially handwashing with soap. This research aims to improve teenagers' understanding of Clean and Healthy Living Behavior (PHBS) and proper handwashing techniques. The method used in this research is counseling, which includes education on the importance of PHBS and demonstration of proper handwashing techniques. The questionnaire results conducted after the counseling show that the majority of teenagers are aware of PHBS and apply it in their daily lives, but there is still a gap between knowledge and PHBS practices. Based on these results, it is recommended to adjust the timing of activities, involve faculty leaders, and provide adequate facilities for the handwashing program with soap in future activities.
Pengaruh eksipien terhadap sifat fisik granul effervescent : Review Pratama, Reza; Munir Alinu Mulki; Saputro, M. Ramadhan; Afifah Rusyda Sani; Ratu Siti Robiatul Awaliyah
An-Najat Vol. 2 No. 1 (2024): FEBRUARI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i1.1071

Abstract

The use of various plant species, which are then formulated using pharmaceutical technology in the form of effervescent granule preparations, is a strategy to increase the practicality and public interest in consuming herbal medicines. The natural ingredients most commonly used as the main ingredients in the manufacture of effervescent granules include fruits, rhizomes, fruit peels, leaves and seeds. Effervescent granules are a mixture of acidic and alkaline compounds which, when added to water, produce a carbon dioxide reaction. This creates a foam that gives a fresh taste effect and can mask unwanted flavours. The purpose of this article is to provide information on the formulation and evaluation of effervescent granules from various plant extracts that may have public health benefits. The method used to collect the data was a search of several journals. The results of the search showed the influence of excipients on the physical properties of the granules. These include organoleptic properties, flow time, dissolution time, water content and pH of effervescent granule preparations.
Co-Authors Affandhy, Adhwa'a Kaylla Afifah Rusyda Sani Ain Luthfiannisa Akifah, Muthia Nur Aldila Divana Sarie Alfina Oktavianti Amanda Maharani Angel Novia Fransiska Anggi Ayu Pratama Anisa Aula Rahma Anisa Fauziah Annisa Frastica Septi Aprillia, Cantika Arline Rahmadianti Kusumawardhani Asman Hitopik Asri Yuniar Aurora Fatimatuz Zahro Azzahra , Khaerunisa Basmalah, Nur Cantika Nurul Sa'adah Chalisya Vanya Advaita Choerunnisa Choerunnisa Datu Muhammad Cordova Debora, Priscinya Christiana Diva Afiah Hanifa Irawan Dwiputri Prihasti, Nurlita Elvira Julia Ariyanto Elyyana, Nina Elzandra Imola Vioniken Eriyanti Astika Esti Syahrin Faizal Auladi Rivianto Fathina Annajla Febry Nola Odhia Fikri Aldebaran Misbah Azizi Giga Anugerah Arsylrakhmatika Gun Gun Gumilar Hariadi , Nayla Nur Azkia Hariadi, Nayla Nur Azkia Hasna, Vina Luthfiana Haura, Izmi Herdiana Verliani Hidayat, Muhammad Naufal Nurhadi Hidayat, Sofianti Ibtisamah Haura Ihsan Alfiandri Indah Laily Hilmi Indah Laily Hilmi Indriyani, Yuni Lili Irene Virda Sakina Isyana S alsabila Jasmine Rahma Saputri Jekmal Malau Jekmal Malau Julianti, Nurlia Karlina Dwi Samratul Jannah Laprilski , Dewi Hanun Lestari, Sepiyani Ayu Madame Marselly Sebayang Maharani, Puteri Rahma Mally Ghinan Sholih Mally Ghinan Sholih Mally Ghinan Sholih Marsah Rahmawati Utami Martia, Elsya Meliana Sari Melisa Intan Barliana Mierza, Vriezka Mochamad Galuh Ryandha Moza Aulia Syifni Muhammad Fajri Maariz Muhammad Ja'far Ash Shidiq Muhammad Naufal Nurhadi Hidayat Muhammad Raka Tresna Mulidini Mulidini Mutia Desvi Putri Mutiara Alfiyah Najah Fatihatul Arifia Najla Yusiana Wahyudi Nanda Diva Meilani Nariyyah Fitriana Nissa Khalida Hanum Nolla Olipia Elva Megrian Nur Darmawan, Shiyami Aulia Nur Komala Fitri Nurfadhila, Lina Nurfirah Mubarok Nurhadis, Nurhadis Nurlia Julianti Nurlita Dwi Putri Prihasti Nurma Dwi Rahmawati Pratama, Reza Prihasti, Nurlita Dwi Putri Priscinya Christiana Debora Putri Setya Tyasna Putri Wahyu Primasti Putri Wulanbirru Rachel Noveriachristie Balapadang Ratu Siti Robiatul Awaliyah Rifa Nur Alia Rima Putri Ramadhani Riska Shafira Rizki Rava Dwi Putra Roudotul Jannah Roudotul Jannah Sa'adah, Cantika Nurul Sa'diyyah, Nur Saarah Hamidah Asmara Indratno Safira Rosyidah Salma Alviyah Salman Salman Salsabila Granadha Nibullah Sanjaya, Velieana Laurent Saputro, M. Ramadhan Septiani, Dia Shafira Intan Anggraini Shalum Putriyani Shinta Puspa Dwiyanti Sholih, Mally Ghinan Siska Bela Safitri Siti Nafisa Siti Nur Istiqomah Siti Nuriah Siti Rohmah Siti Rosilfa Marisa Sofianti Hidayat Sophy Wulandari Sri Rahayu Subekti, Firli Reisya Sudarjat, Hadi Sukma Wibowo, Sepvia Putri Sulistiawati Sulistiawati Syelziva Yonda Atwita Syifa Khairunnisa TIANA MILANDA Tiara Cinta Amelia Tiara Nurayuni Tintia Rafika Putri Tiwi Ambarati Urbaningrum , Lestari Mahardika Vriezka Mierza Welly Windari Yumareta Anggun Yuni Lili Indriyani Yuniar Fathil Ilmi Zakiyah, Wildani Zuyyinna Alya Abbas