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All Journal Biology, Medicine, & Natural Product Chemistry The Indonesian Biomedical Journal Jurnal Biologi Tropis Window of Health : Jurnal Kesehatan Journal of Health Policy and Management JURNAL PENDIDIKAN TAMBUSAI Poltekita : Jurnal Ilmu Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Ilmiah Profesi Pendidikan Window of Community Dedication Journal Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Wal'afiat Hospital Journal INDONESIAN JOURNAL OF HEALTH YASIN: Jurnal Pendidikan dan Sosial Budaya jpki Innovative: Journal Of Social Science Research WAL'AFIAT HOSPITAL JOURNAL
Makmun, Armanto
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : JOURNAL LA MEDIHEALTICO

 1 
Case Report: Hypertension Accompanied by Obesity with Herbal Consumption of Soursop Leaf Boiling Purnama, Indah Dian; Makmun, Armanto; Wijaya, Fanny
Journal La Medihealtico Vol. 5 No. 3 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i3.1343

Abstract

Hypertension is abnormally high blood pressure, measured on at least three different occasions. Hypertension is considered if systolic blood pressure is ≥140 mmHg and diastolic blood pressure is ≥90 mmHg. Currently, hypertension has become a global problem because its prevalence continues to increase from year to year. This disease can trigger other diseases such as stroke, coronary heart disease, heart failure, and kidney disease. Obesity also has a close relationship with the occurrence of hypertension. The greater the body mass, the more blood is needed to supply oxygen and food to body tissues. In addition to pharmacological therapy, one alternative treatment that can be an option to lower blood pressure is to consume herbal plants. One of the herbal plants that can lower blood pressure is soursop leaf decoction. Patients with complaints of headaches, weakness, tension in the back of the neck, accompanied by a history of hypertension and obesity, with a diagnosis of Hypertension and Obesity are given therapy in the form of Paracetamol 500 mg 3x1 and Amlodipine 10 mg 1x1. Pharmacological interventions produced good results, namely controlled blood pressure in patients. The hypertension suffered by the patient is hypertension that is obtained due to several predisposing factors in the patient, namely age, gender, smoking habits, and obesity.
Case Report: Grade II Hypertension Accompanied by Obesity with Consumption of Propolis Herbs Arsa, Sri Asmawati; Makmun, Armanto; Paulus, Paulus
Journal La Medihealtico Vol. 5 No. 3 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i3.1362

Abstract

Hypertension is often said to be a silent killer, because it is a deadly disease without being accompanied by symptoms first as a warning for the victim. Hypertension with the incidence of obesity is still common. The prevalence of hypertension accompanied by obesity also continues to increase. According to some studies, obesity and hypertension have a meaningful relationship. One alternative treatment that can be an option to lower blood pressure is herbal therapy. Herbal medicine is classified as complementary medicine is a phenomenon that appears today among many other non-conventional treatment phenomena, such as treatment with herbs or herbal therapy, acupuncture, and cupping. The use of herbs is one of the alternative treatments chosen by the community other than conventional (medical) treatment.One of the natural products produced is propolis. Propolis is one of the natural products produced by bees and is widely used as a medicine or supplement, anti-inflammatory, disease treatment, accelerating wound healing, and others. The patient in this case is a woman with the age of 50 years. Patients come with complaints of dizziness, headache and low back pain accompanied by a history of hypertension, and obesity. The patient was diagnosed with Grade 2 Hypertension on Treatment, and Obesity was given therapy in the form of Amlodipine 10 mg 1x1, Paracetamol 500 mg 3x1 and Vitamin B Complex 2x1.Hypertension suffered by patients is hypertension obtained due to several predisposing factors in patients, namely diet, obesity, age, and gender.
The Effect of Black Rice Extract on Lipid Profile Changes in Hypercholesterolemic Mus musculus Awalia, Awalia; Makmun, Armanto; Bamahry, Aryanti R.; Rasfayanah, Rasfayanah; Mangarengi, Yusriani
Journal La Medihealtico Vol. 6 No. 1 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i1.1947

Abstract

Increased levels of lipid profiles in the blood affect the occurrence of coronary heart disease. Several large studies have shown that several natural food ingredients rich in antioxidants are associated with a lower incidence of cardiovascular disease. prevent the occurrence of several degenerative diseases. The research design used was a research design with a control group (pretest-posttest control group design). The research design used was a pretest-posttest control group design with 27 mice (mus musculus). They were divided into 3 groups: the negative control group (placebo), the positive control group (simvastatin), and the treatment control group (black rice). The intervention was carried out for 21 days. Data analysis was carried out using the paired T test and one way ANOVA test. Giving black rice extract can significantly improve lipid profile levels in mice, especially increasing HDL cholesterol levels by (10.44%) and decreasing triglyceride levels by (12.89%) as well as Simvastatin administration can also improve lipid profile levels significantly, especially decreased total cholesterol levels by (24.67%) and decreased LDL cholesterol by (32.08%). Based on the one way ANOVA test, P values were obtained successively in the administration of black rice extract, namely total cholesterol (p=<0.001), HDL cholesterol (p=<0.001), LDL cholesterol (p=<0.001), and triglycerides (p=<0.001). Likewise, in the administration of simvastatin, the lipid profile levels were obtained (p = <0.001). The conclusion of this study was that there was a significant effect of giving black rice extract on the lipid profile of hypercholesterolemia mice which was as effective as simvastatin.
The Effect of Nigella Sativa L. Extract on Blood Glucose Levels in Alloxan-Induced Hyperglycemic Mus musculus Khoirunnisa, Nur; Makmun, Armanto; Surdam, Zulfiyah; Nur, Muhammad Jabal; Ardiansar, Abdul Mubdi; Zulfahmidah, Zulfahmidah
Journal La Medihealtico Vol. 6 No. 3 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i3.2055

Abstract

Hyperglycemia is one of the conditions of increasing blood glucose levels. There are various treatment options in patients with hyperglycemia, one of which is non-drug therapy with traditional medicine. A traditional medicinal plant with various benefits, namely black cumin which is known to have a variety of ingredients that can lower blood glucose levels. Knowing the effect of black cumin extract on blood glucose levels in mice with alloxane-induced hyperglycemia. The research design used was a pre and post test with control group design with a total sample of 27 mice divided into 3 groups where each group consisted of 9 heads. Group 1 is the control group while group 2 and group 3 will be treated respectively. The analysis was carried out with a paired sample t-test to see the differences between each group before and after treatment. The results of the study on the average blood glucose levels before treatment and after the administration of black cumin treatment there were changes in each group obtained a significance value of 0.000 at both doses of black cumin extract. Based on the results obtained, it is known that black cumin extract can reduce blood glucose levels where the greater the dose is directly proportional to the decrease in blood glucose levels.
Overview of Eating Behavior, Physical Activity, and Parental Obesity History in Relation to Obesity Incidence Among Medical Students at Universitas Muslim Indonesia Ahyar, Muammar; Makmun, Armanto; Surdam, Zulfiyah; Hidayati, Prema Hapsari; Murfat, Zulfitriani; Hamsah, Muhammad
Journal La Medihealtico Vol. 6 No. 4 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i4.2282

Abstract

Obesity is a global epidemiological problem that poses a threat to world public health, the Word Health Organization annually publishes that obesity is the cause of death of 2.8 million people. Low physical activity is an important predictor of obesity, besides that the family environment has a big influence on the incidence of obesity in a person. The purpose of the study was to determine the description and relationship of eating behavior, physical activity, and parental obesity history with the incidence of obesity. Methods This study is an analytical descriptive study with a cross sectional method, data were collected once from each participant and analyzed with SPSS using the chi-square test. The results revealed that there were 50 umi medical faculty students who were obese, with poor eating behavior as many as 34 people or 68%, less physical activity as many as 36 people or 72%, obese father's obesity status as many as 33 people or 66% and obtained obese mother's obesity status as many as 30 people or 60%. Data analysis shows that there is a relationship between eating behavior and the incidence of obesity in UMI medical students, there is a relationship between physical activity and the incidence of obesity in UMI medical students, and there is a relationship between a history of parental obesity and the incidence of obesity in UMI medical students. Based on the results obtained, it is concluded that eating behavior, physical activity, and a history of parental obesity are one of the factors that cause obesity in UMI medical students.
Polypharmacy Profile in Geriatric Patients Rifa'at, Syahrul; Makmun, Armanto; Nurmadilla, Nesyana; Liaury, Kristian; Sommeng, Faisal; DK, Indah Lestari
Journal La Medihealtico Vol. 6 No. 5 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i5.2636

Abstract

Polypharmacy is a common phenomenon in geriatric patients and is strongly associated with aging and the presence of multiple comorbidities. In the elderly population, the simultaneous use of several medications increases the risk of negative outcomes, including higher healthcare costs, adverse drug reactions, drug–drug interactions, poor medication adherence, functional decline, and geriatric syndromes. Older adults are particularly prone to polypharmacy, which considerably heightens the risk of drug interactions, especially among those with multiple chronic conditions. The probability of drug–drug interactions escalates in direct proportion to the number of medications prescribed, as geriatric patients generally receive more prescriptions compared to younger populations. This study employed a Literature Review approach with a Narrative Review design. Polypharmacy is highly prevalent among geriatric patients and is significantly linked to disease burden, adverse effects, drug interactions, and increased treatment costs. Elderly patients with multiple comorbidities taking several medications concurrently are at heightened risk of harmful drug interactions, with the likelihood rising alongside the number of medications consumed. Geriatric patients are particularly vulnerable to polypharmacy, which substantially increases the risk of drug–drug interactions. The greater the number of medications prescribed, the higher the potential for adverse outcomes.
Co-Authors Abdillah, Andi Rachmat Afrayani, Wirna Ahyar, Muammar Aisyah, Windi Nurul Akbar, A. Muh. Alamanda Irwan, Andi Aminuddin Aminuddin Andi Mappaware, Nasrudin Anugrah, Iqra Ardiansar, Abdul Mubdi Arifuddin, Andi Tenri Sanna Arsa, Sri Asmawati Aryanti Aryanti Ashlihati, Munifah Asmi, Muh. Nurul Avisha, Mirah Awalia, Awalia Bamahry, Aryanti Bamahry, Aryanti R. Basalamah, Putri Azimah Fauzi Bazith, Akhmad Bukhari, Agussalim Burhanuddin Bahar Cahyani, Pramesty Regita Daeng Kanang, Indah Lestari Dahlia Dahlia Dahlia Dahliah, Dahliah Darma, Sidrah Dase, Jerny Dewi M, Anna Sari DK, Indah Lestari El Firman, Andi Mappaita Faisal Syamsu, Rachmat Fakhirah, Muthiah Raghdah fatimah Fatimah Ferry Sandra Gani, Azis Beru Hadi, Santriani Hamsah, Hamsah Hamsah, Muhammad Hamzah, Firmansyah Hamzah, Pratiwi Nasir Hilman, Feisal Ida Royani Indarwati, Rezky Putri Isman, Thalhah Bin Kamaluddin, Irna Diyana Kartika Kamaruddin, M Yusril Karim, Marzelina Kartika K, Irna Diyana Kartika, Andy Visi Khoirunnisa, Nur Kurniyanti, Novia Latief, Shofiyah Liaury, Kristian M, Nasrudin A M. Yogi Riyantama Isjoni Mangarengi, Yusriani Mappaware, Nasrudin Andi Mathius, Denny Mayo, Abbas Ali Mochtar, Shulhana Mokhtar, Shulhana Mokhtar, Sulhana Muhammad Irsan Muhammad Jabal Nur, Muhammad Jabal Mukhtar, Shulhana Mulyadi, Farah Ekawati Mursyid, Muhammad MW. Pettawali, Sitti Ainun Nasruddin, Hermiaty Nesyana, Nesyana Ningsi, Iin Widya Ningsih, Iin Widya Nissatuljannah, Syarifah Fatimah Novriansyah, Zulfikri Khalil Nur Intan, Nur Nurdin, Abbas Zavery Nurdin, Abbas Zavey Nurfadhilah, Nadiyah Nurmadilla, Nesyana Nurwahyuni Ode Arli, Rosmelidian Safari Palloge, Salahuddin Andi Palo, Nurul Aisyah Parningan, Zherant Paulus Paulus Pratama, Arhmad Ardhani Prema Hapsari Purnama, Indah Dian Putra, Fadil Mula Rachmat Faisal Syamsu, Rachmat Faisal Rachmat, Rizqah Aulyna Rasfayanah, Rasfayanah Rianti, Riska Rifa'at, Syahrul Riyanti, Nabilah Satria, Anna Shamad, Muhammad Ishaq Siti Rahma Solly Aryza Sommeng, Faisal Sri Vitayani Sudirman, Farah Zhafirah Sulvita Karsa, Nevi Sumarni Sumarni Surdam, Zulfiyah Syamsu Rijal Syamsu, Rachmat Syamsul Rijal Syamsul, Racmat Faisal Syatirah, Andi Bau Taslim, Nurpudji Astuti Thahir, Ilyas Thahira, Yugni Maula Trika Irianta Ulfa, Nura Usmiah Musa, Amelia Utami, Nurfika Wardayani Wardayani, Wardayani Wijaya, Fanny Yani, Siti Nurindah Yanti, A Kartini Eka Yasid, Nurul Wahidah Yuniar, Andi Irma Yusriani, Yusriani Yusril, Moh. Yusuf, Andini Zahiyah, Azzah Zahra Nizrina, Alfiyya Zulfa, Atria Putri Zulfahmidah, Zulfahmidah Zulfitriani Murfat