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All Journal ADMINISTRASI PUBLIK Jurnal Pustaka Ilmiah Al-Mishbah: Jurnal Ilmu Dakwah dan Komunikasi Jurnal Insan Farmasi Indonesia Jurnal Cakrawala Ilmiah Jurnal Riset Farmasi Journal of Innovation Research and Knowledge CEMERLANG :Jurnal Manajemen dan Ekonomi Bisnis Jurnal Pendidikan, Sains dan Teknologi Jurnal Mahasiswa Ilmu Kesehatan Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Vitamedica: Jurnal Rumpun Kesehatan Umum Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Kreasi: Jurnal Pengabdian Masyarakat Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Inovasi Kesehatan Global Vitamin: Jurnal Ilmu Kesehatan Umum Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Sains Farmasi dan Kesehatan Jurnal Riset Multidisiplin Edukasi AT-TAKLIM: Jurnal Pendidikan Multidisiplin
Nor Latifah
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Religion Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Vitamin: Jurnal Ilmu Kesehatan Umum

 1 
Artikel Review: Dampak Limbah Farmasi terhadap Lingkungan dan Upaya Pengelolaannya di Industri Muhammad Rezky Wahyudi; Hidayatur Rizky; Ufaul Apriani; Nor Latifah
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 3 No. 3 (2025): Juli: Vitamin : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v3i3.1442

Abstract

The pharmaceutical industry produces solid, liquid, and gaseous waste containing active pharmaceutical ingredients that pose serious environmental risks. These wastes can disrupt ecosystems and accelerate antimicrobial resistance. This systematic literature review examines pharmaceutical waste concepts, classifications, characteristics, and relevant regulatory frameworks. It also addresses ecotoxicological effects on aquatic and terrestrial ecosystems, antibiotic contamination and resistance, water and soil pollution, treatment technologies, industrial policies, and best practices. Findings show that conventional wastewater treatment is largely ineffective at removing pharmaceutical residues, resulting in their presence in surface water, soil, and even drinking water. Compounds such as β-blockers, cytostatics, antibiotics, and hormones harm aquatic life by impairing reproduction and causing mutations. Antibiotic-laden industrial waste contributes to the emergence of resistant bacteria. Recommended treatment methods include biothermal processes, advanced oxidation (e.g., UV/H₂O₂, ozonation), adsorption (activated carbon), coagulation-flocculation, and controlled incineration. Stronger enforcement of hazardous waste regulations (e.g., Government Regulation No. 101/2014, Ministry of Environment and Forestry Regulation No. 56/2015) and adherence to WHO (2025) guidelines are essential. In conclusion, multisectoral collaboration (One Health), improved waste treatment capacity, and adoption of best practices are crucial to preventing pharmaceutical pollution and promoting environmental sustainability.
Uji Stabilitas Fisik dan Kimia Sediaan Tablet Parasetamol dalam Berbagai Kondisi Penyimpanan M. Jian Prayoga; Maulida Maulida; Maura Putri Ariqah; Nor Latifah
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 3 No. 3 (2025): Juli: Vitamin : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v3i3.1458

Abstract

Paracetamol is a widely used analgesic and antipyretic drug in tablet dosage form. Ensuring the stability of paracetamol tablets is essential to maintain drug efficacy, safety, and quality during their shelf life. This study aims to evaluate the physical and chemical stability of paracetamol tablets stored under different temperature and humidity conditions. The review method used in this article involves analyzing published data from several sources, focusing on changes in physical appearance (color, shape, and odor) and chemical parameters such as active pharmaceutical ingredient content over time. The findings indicate that higher temperatures and humidity accelerate degradation and affect the drug's quality, particularly through discoloration and reduction in active content. Packaging also plays a crucial role in maintaining stability, especially in tropical climates. The results highlight the importance of stability testing in pharmaceutical quality assurance and support the application of Good Manufacturing Practices (GMP) and appropriate storage guidelines. This paper contributes to the understanding of stability profiles of commonly used drugs and provides a reference for the formulation and packaging development of heat-sensitive medications.
Analisis Metode dalam Pengemasan Obat Primer dan Sekunder di Industri Farmasi Fayza Nindya Nur’Assyfa; Nia Kusumadewi; Nor Latifah
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 3 No. 3 (2025): Juli: Vitamin : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v3i3.1473

Abstract

Optimization of primary and secondary packaging is crucial for the quality and efficiency of drug production. The drug packaging process consists of primary packaging that is in direct contact with the product and secondary packaging that provides additional protection and important information. This study aims to analyze various methods applied in pharmaceutical packaging to assess the effectiveness of Lean Manufacturing (VSM), Single Minute Exchange of Dies (SMED), and Overall Equipment Effectiveness (OEE). This study shows that VSM significantly reduces the time of secondary packaging activities. SMED reduces the lead time of primary packaging analysis by 58.06%. Meanwhile, OEE analysis of primary packaging identified high set-up/adjustment as the main cause of losses. The importance of implementing structured methods to increase productivity, reduce waste, and ensure a more efficient and effective packaging process in the pharmaceutical industry, contributing to improving product quality and safety.
Co-Authors Abu Dzar Alghifary Adelia Ikrima Ahmad Muhaimin Aida Savitri Akhmad Rizky Akbar Alfia Mujahra Ali Iskandar Zulkarnain Alya Anggryanti Amaliya Bunga Dwiyanti Amanda Cahyani Anisa Anisa Annisa Annisa Annisa Normiani Putri Annisa Zahra Annur tasya alfiati Aulia Azkia Aura Nasyafa Cheina Nazerina Yoshi Della Prastyka Della Puspita Desy Maimunah Devira Niken Putri Ferdinand Dhea Nadilla Dhiya Shoufi Sahaja Elita rahmah Erlina Fatmasari Fathiyatur Rahmah Fatimah Salsabila Algina Fayza Nindya Nur’Assyfa Fiona Maulidia Ghina Faiha Ghina Rahima Gina Norhalija Hairun Nisa Hairunnisa Hairunnisa Hairunnisa Halimi, Halimi Hana Salma Cantika Harris Noorrahman Hayatun Nissa Helsy Indarwati Hidayatur Rizky Husain, Aghnaita Iqbal Nurwahid Irma Muthiah Irma Nadia Yanti Jaida Rahma Jannatun Nisa Jayawarsa, A.A. Ketut Jenni Getbriela T Khusnul Khotimah Laila manada Lidya Syahjiah Luthfia Raisah Ahyati M Jian Prayoga M. Chaidir Hafidz M. Jian Prayoga Mahabatul Hasanah Marisa Susanti Maulida Maulida Maura Putri Ariqah Mifta Dewi Mikdat Adam Muhammad Arif Akbar Muhammad Dhaiffullah Muhammad Fadhli Muhammad Faqih Madhani Muhammad Fathur Rahman Muhammad hafiz adha Muhammad Lukmannul Hakim Muhammad Muhammad Muhammad Reihan Ridha Muhammad Rezky Wahyudi Muhammad Rizky Muhammad Romansyah Khatami Muhammad Zairullah Nabila Sativa Nabila Syifa Firdaus Nabilah Nabilah Nabilah Nadia Nadia Nadila Nadila, Nadila Nailia Nur Isma Sumarno Nia Kusumadewi Nicky Saputra Niken Widya Ningrum Nisa Aulia Sera Nita Rahmadani Noor Kamalliyah Noor Mila Wati Nor Tiara Sari Norhikmah Nur Latipah Sulistiawanti Nur Lutfia Salim Nur Luthfia Salim Nur Prettiya Salha Nur Rifa Ashya Nurul Hasni Julianti Nurul Mas'adah Nurul Mas’adah Oktriyisa Tantia Mini Padma Azzahra Ramadhani Putri Novianur Ramadhani Rakha Widyastama Ratna Habibah Raudatul Hasanah Raudatul Jannah Regina Nabila riauwati, Rosa Ridha Febriyanti Rifka Annisa Rima Hindriani Rina Rina Rina Sa'diah Rina Suspa Nita Riska Hidayah Salma Fitriyanti Silvia Rismawati Sindy Maulida Siti Fatimatuzzahra Siti Nor Adidah Siti Nurhaliza Sri Hidayati Sri Muliany Sri Tami Dewi Suciati Nurrani SUNARNO Surya Alvina Nazaha Taufik Akbar Trisnia Widuri Ufaul Apriani Veressa Alfianti Wima Triana Yenni Hafizah Yulianita Pratiwi Indah Lestari Yumna Zaida Zalmi, Zalmiati Zulfa Muthi’ah ⁠Marisa Susanti ⁠Peni Oktariyani Putri