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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Kesehatan Andalas Jurnal Penelitian Kesehatan Suara Forikes Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Kesehatan Komunitas Majalah Kedokteran Andalas Majalah Patologi Indonesia Health and Medical Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga International Journal of Nasopharyngeal Carcinoma Andalas obstetrics and gynecology journal Science Midwifery Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Ilmu Kesehatan Indonesia (JIKSI) Indonesian Journal of Cancer Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Jurnal Riset Ilmiah
Aswiyanti Asri
Departement Of Patology Anatomi, Faculty Of Medicine, Universitas Andalas, Padang
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Science Midwifery

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Challenges in diagnosing schwannoma mimicking thyroid neoplasms on frozen section Ramadhani, Rahmi; Mayorita, Pamelia; Asri, Aswiyanti; Mulyani, Henny; Novianti, Hera
Science Midwifery Vol 13 No 2 (2025): June: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i2.1977

Abstract

Schwannoma is a benign soft tissue tumor of the nerve sheath, composed of neoplastic cells with Schwann cell differentiation. It predominantly arises from peripheral nerves in the head, neck, and extremities, with a peak incidence in the fourth to sixth decades. Schwannoma is typically a solitary and sporadic lesion, affecting individuals of all ages, with an incidence rate of 4.4-5.23 cases per 100,000 people. The prevalence is around 7% of all primary nervous system tumors, often occurring in the head and neck (20-50%) and affecting cranial nerves such as N. Vagus and N. Sympathetic. This case report involves a 50-year-old female patient presenting with a right neck lump that had been present for 23 years, initially small but growing rapidly in the last 10 years with occasional pain. Initial imaging suggested a thyroid complex cyst, but further investigation, including a CT scan and intraoperative frozen section examination, raised suspicion for a malignant thyroid tumor. However, histopathological analysis confirmed the diagnosis of Schwannoma, distinguishing it from other potential malignant lesions, such as Anaplastic Thyroid Carcinoma (ATC). This case highlights the importance of intraoperative cytology and frozen section techniques for diagnosing Schwannoma. Although Schwannomas share morphological similarities with other tumors, particularly in the thyroid region, a multidisciplinary approach combining clinical, radiological, and histopathological findings is essential for an accurate diagnosis. This case also underscores the need for careful differential diagnosis in nerve sheath tumors located in the neck.
Co-Authors Adrial Adrial Adrial Adrial Afriani - Afriani Afriani, Nita Aisyah Elliyanti Alan Mustaqim Almurdi Almurdi Andi Friadi Anggrainy, Fenty Antonius, Puja Agung Arifuddin Arifuddin Aristya Rahadiyan Budi Arni Amir Arnofyan, Budi Pratama Asril Zahari Asril Zahari Bestari Jaka Budiman Bobby Indra Utama Daan Khambri Danuwirya, Muhammad Reko Deddy Saputra Desi Aliefia Dessy Arisanti Dia Rofinda, Zelly Dia Dian Pertiwi Dini Andri Utami Dutia Gestin Dutia Gestin Edison Eka Fithra Elfi, Eka Fithra Eka Nofita Elmatris Sy Endrinaldi Endrinaldi Endrinaldi Etriyel Myh Febriyanti, Rizka Fedrivia, Rannia Ginting, Desi Scorpinasari Hafni Bachtiar Hardian, Sonny Hardisman Hasmiwati Hasnaini Hasnaini henny Mulyani Henny Mulyani Hera Novianti Hera Novianti Hera Novianti Hera Novianti Hera Novianti, Hermafasya, Ayu Octarin Hirowati Ali Histawara Subroto Husna Yetti Husnil Kadri iftahillah - iftahillah Iwani Rahmah Rambe Julizar Julizar Kamelia, Muthia Karmia, Hudila Rifa Kusumardani, Dini Laila Isra Laila Isrona liana, nana Lismawati Rasyd Malinda Meinapuri Mayorita, Pamelia Meta Zulyati Oktora Miftah Irramah Mohamad Reza Muflikal Hamdi Muhamad Febry Muthia Kamelia Nabilla Mahyenda Nadhira Isza Qushoyyi Nadia Oktarina Nana Liana Nana Liana Nana Liana Nita Afriani Nizar, RZ Nova Fenita Sari Noverial Noverial Novianti, Hera Noza Hilbertina, Noza Nuzulia Irawati Oktora, Meta Zulyati Pamelia Mayorita Pemuda, Haris putri, amanda Putri, Rizqy Nurfathonah R Zuryati Nizar R. Zuryati Nizar Rachmadijah Zuryati Nizar Rahmani Welan Rahmi Ramadhani Randi Septiah Hendri Rauza Sukma Rita Resti Aulia Fitri Rizka Fitria Husni Rosfita Rasyid RZ Nizar RZ Nizar Salmiah Agus Salmiah Agus Salmiah Agus Salsabila Muslim Salsabilla Firdaus Sari, Nova Fenita Sari, Rini Purnama Selly Alinta Syukri Shofi Faiza sondang - nora Sorayya A'dilah Putri Suci Rahmadhani Sukri Rahman Susanto Winarko Syamel Muhammad Teddy Kurniawan Tofrizal Tuti Lismayarni Utami, Dini Andri Valencia Valencia Valencia Valencia Valencia, Valencia Vashti Resti Putri Firdaus Wirsma Arif Harahap Yanwirasti . Yenita . Yenita Afriyeni Yessy Setiawati Yessy Setiawati Yuastika Puspita Sari Yulistini, Yulistini Zuryati Nizar, Rachmadijah