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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Hemera Zoa VALENSI Jurnal MIPA Biologi Edukasi : Jurnal Ilmiah Pendidikan Biologi Jurnal Ilmu-Ilmu Peternakan (Indonesian Journal of Animal Science) Jurnal Peternakan Indonesia Proceeding International Conference on Global Resource Conservation JITRO (Jurnal Ilmiah dan Teknologi Peternakan Tropis) Jurnal Ilmu Produksi dan Teknologi Hasil Peternakan BERITA BIOLOGI Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Bioma : Jurnal Biologi Indonesia Jurnal Ilmu Kefarmasian Indonesia Jurnal Abdimas ADPI Sains dan Teknologi Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis
A.S. Satyaningtijas
IPB University, Bogor
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Physics Public Health Veterinary Other

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Effects of Physalis angulata Leaf Extract on Female Reproductive Organs Following Busulfan Injection in Rats Satyaningtijas, Aryani; Ekastuti, Damiana Rita; Tarigan, Ronald; Prasetyaningtyas, Wahono Esthi; Adnyane, I Ketut Mudite; Mohamad, Kusdiantoro; Rahmadhani, Elsi; Sulistyana, Yanti; Mahendra, Arindina
HAYATI Journal of Biosciences Vol. 33 No. 2 (2026): March 2026
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.33.2.490-498

Abstract

Physalis angulata L. (ciplukan) is traditionally used as an herbal remedy with anticancer and antioxidant properties. At the same time, busulfan, a chemotherapy alkylating agent, causes gonadotoxicity and oxidative stress that impair female reproduction. This study aimed to evaluate the effect of P. angulata on reproductive function after busulfan administration in female rats. Twenty-five 6-week-old female rats were randomly divided into: Group I (control), Group II (busulfan only), Group III (P. angulata only), Group IV (busulfan followed by P. angulata after 14 days), and Group V (busulfan and P. angulata administered for 28 days). FSHR and LHR expression in the ovaries and MDA levels in the ovaries and uterus were measured to assess reproductive changes. Busulfan showed no significant effect on FSHR and LHR, whereas P. angulata induced downregulation, suggesting a potential negative feedback mechanism on ovarian receptors. Ovarian MDA showed a decreasing trend with combined treatments, while uterine MDA peaked after busulfan but declined markedly with P. angulata, indicating its role in alleviating oxidative stress. In conclusion, P. angulata may modulate hormonal balance in rat ovaries and decrease oxidative stress in the uterus after busulfan treatment.
Laju Metabolisme dan Saturasi Oksigen Kelelawar Pemakan Buah (Cynopterus titthaecheilus) Hanadhita, Desrayni; Maheshwari2, Hera; Sismin Satyaningtijas, Aryani; Agungpriyono, Srihadi; Rahma, Anisa
Acta VETERINARIA Indonesiana Vol. 13 No. 3 (2025): November 2025
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.13.3.231-239

Abstract

Metabolic rate and oxygen saturation are crucial factors in understanding the physiology of fruit bats (Cynopterus titthaecheilus and Cynopterus brachyotis). This study aims to evaluate the resting metabolic rate and oxygen saturation in bats and their relationship to flight physiology. A total of 32 bats were categorized based on species, sex, and age. Metabolic rate was measured using a metabolic chamber method, while oxygen saturation was monitored using a patient monitoring system. The results showed that bat metabolism is influenced by various factors, including age and sex, without a significant correlation with body mass. Adult female bats exhibited highly fluctuating metabolic rates, possibly due to hormonal factors and increased energy demands during lactation. Additionally, C. titthaecheilus had an oxygen saturation of 94%±2.00 for males and 94%±1.73 for females, whereas C. brachyotis showed 98%±0.00 in males and 87%±4.16 in females. The high oxygen saturation in bats indicates an efficient oxygen transport system that supports their high metabolic activity during flight. This study provides insights into the physiological strategies of bats in maintaining high metabolism and oxygenation capacity, which are relevant to their ecology and overall health.
Co-Authors . andriyanto A. Suprayogi A. Wijaya Abadi Sutisna Abadi Sutisna Achmad Dinoto Achmad Dinoto Adam Kustiadi Nugraha Adi Winarto Adisti Dwijayanti Adkhilni Utami Adrien Jems Akiles Unitly Adrien Jems Akiles Unitly, Adrien Afnan, R. Agik Suprayogi Agus Wijaya Ahmad Tjahja Nugraha, Ahmad Tjahja Ainul Khadija Saleema Alif Iman Fitrianto Alvina Gitacahyani Ardiana Andayani, Prawita Lintang Andhika Yudha Prawira Andhika Yudha Prawira Andriyanto Andriyanto Andriyanto Andriyanto Anisa Rahma, Anisa Ardiansyah Nurdin Arief Boediono Arif Darmawan Armando Ramadhoni Athirah Rerana Fitrianthy Aulia Andri Mustika Bambang Kiranadi Bambang Kiranadi Bambang Kiranadi D. R. Ekastuti Dalia Sukmawati Damhuri Damhuri Damiana Rita Ekastuti Danang Dwi Cahyadi David Anwar Dede Sukandar Desrayni Hanadhita Desrayni Hanadhita Desrayni Hanadhita Desrayni Hanadhita Desrayni Hanadhita Dewi Prabuwati Dewi Ratih Agungpriyono Dewi, Fitriana Dirwan Rahman Divo Jondriatno Divo Jondriatno Dwi Nurhidayah Zubaidah Elok Budi Retnani Epi Taufik Eva Harlina Evalina E Evalina E, Evalina F. B. Harlimawan Fitriana Dewi Frans Dhyanagiri Suyatna Hadiyanti, Cresensia Rara Hanadhita, Desrayni HERA MAHESHWARI Hernomoadi Huminto Heru Setijanto Huda Salahuddin Darusman Huda Shalahudin Darusman IETJE WIENTARSIH Ika Amalia, Ika Indra Bachtiar Irwan Oktoni Isdoni Bustaman Jefri Naldi Joko Pamungkas Julianto . Jumadin, La Kelvin Yaprianto Ketut Adnyane Mudite Khoirun Nisa koekoeh santoso Kusdiantoro Mohamad La Jumadin La Jumadin La Ode Sumarlin Lili Darlian Lili Darlian Lina Novianti Sutardi Madyastuti, Rini Maharani Salsabila Mahendra, Arindina Maheshwari2, Hera Maryce Agusthinus Walukou Mawali, Maharja Meta Levi Kurnia Moh. Mursyid Fachrudin MUHAMMAD ADIB MUSTOFA Muhammad Ardiansyah Nurdin Muhammad Zhaahir MULYATI EFFENDI N. Kusumorini Nastiti Kusumorini NASTITI KUSUMORINI Nastiti Kusumorini NASTITI KUSUMORINI Natalia, Ratna Delima Niken Ulupi Nugroho, Radhitya Aryo Nur Isnaini Ulfa Nurul Masyita, Nurul P. Achmadi Parwati, E. D. Pudji Achmadi Purnomo . R. Tarigan Raden Yufiandri Rahma Anisa Rahmadhani, Elsi Rahminiwati, Min Ramadhoni, Armando Ratna Delima Natalia Regina Wulandari Resti Rahma Dianti Rita Dwi Rahayu Rita Dwi Rahayu Ronald Tarigan Rudi Afnan Sandra Hapsari Sandra Hapsari Santa Nova A Siburi Savitri Novelina Sa’diah, Siti Siswahyudianto Sri Estuningsih Srihadi Agungpriyono Suci, Yulia Sulistyana, Yanti Supiyani, Atin Supratikno, Supratikno Sus Dherti Widhyari Tarigan, Ronald Thol’at Hamdi Trioso Purnawarman Ulupi, N. Umi Cahyaningsih Vinda Mulyetti Darwin W. Manalu Wahono Esthi Prasetyaningtyas Warysatul Ummah Widhyari, Sus Dherti Wining Astini Wisnugroho Agung Pribadi Wisnugroho Agung Pribadi YENI KEZIA BEKALANI Yulia Suci Yulia Suci Rahmadani Yulvian Sani Zulvia Maika