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36. Testicular histopathology of mice (Mus musculus) which have been exposed to cigarette smoke and given red watermelon extract (Citrullus vulgaris) Ayu Agita Ginting; Ummu Balqis; Hamny Hamny; Cut Dahlia Iskandar; Zainuddin Zainuddin; T. Armansyah; Fitriani Fitriani
Jurnal Medika Veterinaria Vol 13, No 2 (2019): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v13i2.3564

Abstract

 This research aims to know the testicular histopathology of mice that have been exposed to cigarette smoke and given red watermelon extract dosage 22 mg and 44 mg. Experimental research using completely random design (RAL) with 4 group treatments. The negative control group (KN). The positive control group (KP) which have been exposed to cigarette smoke. Treatment group 1 (K1) which have been exposed to cigarette smoke and given the red watermelon extract 22 mg. Treatment group 2 (K2) which have been exposed to cigarette smoke and given the red watermelon extract 44 mg. Exposed to cigarette smoke conducted in the morning for an hour to burn one cigarette and red watermelon extract given in the afternoon. This was done for 30 days. On day 31, mice were sacrificed and their testis were taken to weighed and made histology slide. The data were analyzed using ANOVA in one direction and continued with Duncan. The results of this research showed that the extract of red watermelon for 30 days looks a highly significant effect (P 0.05) to the diameter of the seminiferous tubules, the number of spermatogonia cells, primary spermatocytes cells, spermatid cells. While on the weight of the testes showed no real effect (P 0.05). Red watermelon extract dosage 22 mg dan 44 mg of the mice exposed cigarette smoke can prevent cell damage in mice testis.
20. The Histological Structure of Tegal Duck (Anas javanicus) Spleen at Different Age Nabila Latifa Hafizsha; Hamdani Budiman; Hamny Hamny; Dian Masyitha; Cut Dahlia Iskandar; Ummu Balqis; Muhammad Jalaluddin
Jurnal Medika Veterinaria Vol 11, No 2 (2017): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v11i2.3522

Abstract

The aim of the  study was to determine the histological structure of tegal duck (Anas javanicus) spleen according to ages variation. One month, 2 month and 3 months of tegal duck were used as the sample of this study. The spleen of each duck was analyzed by Hematoxylin-Eosin (HE) method, then observed under light microscope. The result of this study performed there were the differences of histological structure of the ducks spleen. The capsule thickness had increased along with increasing age, which was 16.0 ± 1.0 µm; 25.3 ± 2.5 µm; and 29.0 ± 1.0 µm. The boundary between the two pulp in the tegal duck 3 months  old more obvious than 1 month or 2 months old. The diameter of white pulp had increased in the oldest duck. It can be concluded that the development of spleen histological structure was more perfect with the  increasing age of tegal duck.
2. The Effect Of Sipatah-patah (Cissus quadrangularis Salisb) Extract On The Femur Bone Density of White Rat (Rattus norvegicus) with Model Ovariectomy Mustafa Sabri; Debby Novita ayumi; Muhammad Jalaluddin; Hamny Hamny; Cut Dahlia Iskandar; Herrialfian Herrialfian
Jurnal Medika Veterinaria Vol 13, No 1 (2019): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v13i1.4108

Abstract

This research aimed to determine the effect of giving Sipatah-patah extract toward the histopathological and femur bone growth of white rat that was ovariectomized. The experimental animals that were used were 12 white rats divided into 4 treatment group with 3 repetitions. K0 was the ovariectomized rat without giving Sipatah-patah extract (ESP); K1, K2 and K3 were ovariectomized rats which were given Sipatah-patah extract with multilevel doses of 500 mg/kg BW, 700 mg/kg BW and 900 mg/kg BW for 30 days. On the 31st day, rats were euthanized using chloroform and os femur that was taken to being made into histological preparation.  There was the decrease in the bones density of the K0 group which is characterized by thinning of trabecular structure, there were lots of osteoclast cells on the edge of the trabecular and lower density of active osteoblasts and passive osteoblasts. The rat of group K1 and K2 showed an improvement on the trabecular structure and lower osteoclast than group K0. The rat of group K3 had a visible improvement of the most congested trabecular structures, cohesive with the most density cell of active osteoblasts than the other groups. The result of this research concluded that the giving of Sipatah-patah extract doses 900 mg/kg BW showed a higher density of trabecular and active osteoblasts than the control group, K1 and K2 on the white rat bones that were ovariectomized.
EFEK PENINGKATAN SUHU TERHADAP JUMLAH LEUKOSIT IKAN NILA (Oreochromis niloticus) (The Effect of Temperature Increase on Leukocyte Count of Nile Tilapia (Oreochromis niloticus)) Nauval Gibran Lubis; Sugito Sugito; Zuhrawati Zuhrawati; Zuraidawati Zuraidawati; Nuzul Asmilia; Hamny Hamny; Ummu Balqis
Jurnal Medika Veterinaria Vol 10, No 1 (2016): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v10i1.4033

Abstract

The aim of this research was to find out the effect of water temperature increase on leucocyte count of nile tilapia. The blood sample from 9 tilapia with weigh of 40-50 g were used in this study. The research was conducted using completely randomized design (CRD) with 3 treatments and 3 replications. Treatment P1 as a control with aquarium temperature was maintained at 29±1 C. Water temperature in treatment P2 and P3 was maintained at 32±1 C and 35±1 C respectively. The aquarium size in each treatment group was 80x60x40 cm with height of water 30 cm. The treatment was done for 15 days and on day 16th, the blood were collected from caudal vein. Data were analyzed with analysis of variance (Anova) and followed with Duncan's multiple range test. The result showed that total leucocyte count (x 105/mm3) of nile tilapia in group P1, P2, and P3 were 3.08±0.88, 1.70±0.52, and 1.69±0.20 respectively. lts showed that an increase in temperature significantly affect (P0.05) the leucocyte count of nile tilapia. The conclusion of this research is the increase in water temperature in aquarium decrease the leucocyte count of nile tilapia.
GANGLION SIMPATIS PADA KAMBING LOKAL (Capra sp.) Idawati Nasution; Nanda Yuliansyah; Hamny -
Jurnal Medika Veterinaria Vol 7, No 1 (2013): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v7i1.2911

Abstract

Penelitian ini bertujuan mengetahui struktur anatomi dan letak ganglion simpatis pada kambing lokal (Capra sp.).  Penelitian ini menggunakan empat ekor kambing (dua ekor jantan dan dua ekor betina), rata-rata berumur 2 tahun. Struktur anatomi ganglion dilakukan dengan cara inspeksi dan palpasi setiap ganglion yang diamati. Letak ganglion dideskripsikan berdasarkan letak ganglion terhadap buluh darah atau nervus yang berada di sekitar ganglion. Hasil pengamatan dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa terdapat empat ganglion dari syaraf simpatis pada kambing lokal yaitu ganglion cervicale cranial yang terletak di dorsal arteri occipitalis dan di caudo-medial nervus vagus. Ganglion cervico-thoracicum/stellatum berada di cranial ramus communicantes, di caudal arteri dan vena costocervicovertebralis, di lateral trakea dan di ventral nervus vertebralis. Ganglion celiaco-mesentericum/solare terletak di dorsal arteri mesenterica cranialis dan caudal arteri celiaca. Ganglion mesentericum caudale terletak di antara arteri umbilicalis dextra dan sinistra serta di dorsal arteri sacralis mediana.Dsimpulkan bahwa ganglion celiaco-mesentericum/solare memiliki struktur anatomi yang berbeda dibandingkan dengan ketiga ganglion simpatis lainnya pada kambing lokal
Immunoexpression of aortic endothelial P-selectin and serum apolipoprotein A-1 levels after administration of arabica (Coffea arabica) and robusta (Coffea canephora) coffee bean extracts: In vivo study in atherosclerosis rat model Ekawati, Wahyu; Heriansyah, Teuku; Kamarlis, Reno K.; Purnawarman, Adi; Sofyan, Hamny; Enitan, Seyi S.
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.794

Abstract

Atherosclerosis is a leading cause of cardiovascular disease-related death worldwide. Some studies suggested that the natural ingredients in coffee may negatively affect cardiovascular diseases, while other studies indicated that coffee contains anti-inflammatory compounds that are beneficial for cardiovascular diseases. The aim of this study was to measure the expression of P-selectin in aortic endothelial cells and the level of serum apolipoprotein A-1 (ApoA-1) in an atherosclerosis rat model after the administration of arabica and robusta coffee bean extracts at mild-moderate and high doses. An experimental study was conducted with a complete randomized design using 36 adult male white rats (Rattus norvegicus) divided into six groups: negative control (NC), positive control (PC), arabica mild-moderate dose (A1), arabica high dose (A2), robusta mild-moderate dose (R1), and robusta high dose (R2). Animals were induced atherosclerosis with atherogenic feed and then were treated with arabica and robusta coffee bean extracts at two different doses for four weeks. The results showed that the expression of P-selectin in the group of rats treated with robusta coffee bean extract was lower than arabica coffee bean extract group. Rats with robusta coffee bean extract mild-moderate dose had the highest ApoA-1 levels compared to other groups significantly (p<0.05). The level of ApoA-1 was higher in both mild-moderate and high dose of robusta coffee groups compared to the negative control group (both with p<0.001). In conclusion, mild-moderate intake of robusta coffee bean extract could reduce aortic P-selectin immunoexpression and increase serum ApoA-1 levels in an atherosclerosis rat model.
Vaskularisasi Pembuluh Darah Arteri Mata (Organum visus) pada Kambing Lokal (Capra sp.) Idawati Nasution; Ezy Yulanda Rezki; Hamny Hamny
Jurnal Agripet Vol 13, No 1 (2013): Volume 13, No. 1, April 2013
Publisher : Agricultural Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17969/agripet.v13i1.549

Abstract

Eye (organum visus) vascular of local goat (capra sp.)ABSTRACT. The aim of the study was to determine of eye vascular in local goat (Capra sp.) The study used a local goat, aged 2 years old. Observation was made after specimen preparation. The observations was documented using a digital camera and analyzed descriptively. The vascular to the eye originated from externa ophthalmica artery and divides into several branched musculares arteries, lacrimalis artery, rete mirabile ophthalmicum gives off supraorbitalis artery, ethmoidalis artery, anteriores ciliares arteries and anastomoses with interna ophthalmica artery and devides into lateralis posterior longae ciliares arteries and medialis posterior longae ciliares arteries and the terminal branched into lateralis posterior shortae ciliares arteries and medialis posterior shortae ciliares arteries. Superficial temporalis artery gives off two branches lateralis inferior palpebral artery and lateralis superior palpebral artery. Malaris artery gives off two branched medial inferior palpebral artery and medial superior palpebral artery.
SUPERVISI PEMERIKSAAN DAN PENYEMBELIHAN HEWAN QURBAN YANG ASUH DI GAMPONG TUNGKOP KECAMATAN DARUSSALAM KABUPATEN ACEH BESAR Makmur, Ali; Jalaluddin, Muhammad; Yulisma, Rika; Sofyan, Hamny; Wahyuni, Sri; Isky, Saiful; Novita, Andi; ., Daniel; Fahrezi, Muhammad Gilbran
Jurnal Media Tropika Vol 4 No 2 (2024): Jurnal Media Tropika
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/mediatropika.v4i2.18650

Abstract

Personal hygiene is an action taken to maintain cleanliness and health for an individual’s physical and mental well-being. Good personal hygiene practices minimize the entry of microorganisms, thereby reducing the risk of individuals contracting diseases. ASUH, which stands for Safe, Healthy, Whole, and Halal, can be used as an indicator of food suitability for processing and human consumption. This community service activity aimed to supervise the effort to ensure the eligibility of sacrificial animals in Gampong Tungkop, Darussalam District, Aceh Besar Regency, through ante-mortem and post-mortem examinations. The animals examined included 24 cows and 6 goats ready for slaughter. The examinations consisted of ante-mortem examination, which covered the general condition, teeth, health status, eye mucosa, anus, absence of defects, sufficient age, not emaciated, and male gender. Post-mortem examination, which assessed the condition of the meat and visceral organs, including the liver (hepar), small intestine (intestinum tenue), large intestine (intestinum crassum), stomach (ventriculus), kidneys (ren), lungs (pulmo), spleen (lien), and heart (cor). Observations showed that the eye mucosa color of the examined cows and goats was generally pink, indicating normal conditions. All cows and goats examined were healthy and had perfect physical conditions (no defects). The post-mortem examination results showed that the meat, stomach, spleen, heart, lungs, and kidneys were in normal condition. However, endoparasites of the Fasciola hepatica type were found in the livers of five slaughtered cows. Health conditions of the supervised cows and goats met the requirements for sacrificial animal slaughter.
Ascorbic acid and calcitriol as alternative preventive strategies for myocardial damage in type 2 diabetes mellitus: an in vivo study using diabetic and atherosclerotic rat models Saputra, Jefri Dwi; Heriansyah, Teuku; Sofyan, Hamny; Dimiati, Herlina; Mudatsir, Mudatsir
Heart Science Journal Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.01.14

Abstract

BACKGROUND: Type 2 diabetes mellitus can increase the production of reactive oxygen species (ROS) and genetic transcription factors, such as nuclear factor kappa beta (NF-κB). These phenomena may enhance the progression of atherosclerosis. Additionally, NF-κB can induce apoptosis of pancreatic beta cells and accelerate disease progression. OBJECTIVE: To investigate the role of calcitriol and ascorbic acid on NF-κβ expression in vivo in aortic and myocardial tissues of Wistar rats. METHODS: This randomized experimental study involved 24 male Wistar rats of the Rattus norvegicus strain, divided into four groups: NC (negative control), PC (positive control), AG (ascorbic acid group), and CG (calcitriol group). The study spanned 90 days, including a 30-day intervention period. Aortic and myocardial samples were processed into histological preparations and stained using immunohistochemical techniques. NF-κB expression was assessed using an intensity scoring method. RESULTS: The CG group demonstrated the lowest NF-κB immunoexpression in myocardial tissue (0.27 ± 0.08), followed by the AG (0.37 ± 0.05), NC (0.68 ± 0.08), and PC (1.13 ± 0.34) groups, with statistically significant 3sbetween the groups (p < 0.05). In aortic tissue, the CG group also exhibited the lowest NF-κB expression (0.30 ± 0.18), followed by the AG (0.50 ± 0.09), NC (0.97 ± 0.05), and PC (1.23 ± 0.38) groups, with statistically significant differences between the groups (p < 0.05).  Similar trends were observed in the immunohistochemical staining of the NF-κB antigen in myocardial and aortic tissue samples. Calcitriol administration was more effective than ascorbic acid in reducing NF-κB expression in both myocardial (p < 0.05) and aortic tissues (p < 0.05). CONCLUSION: Both ascorbic acid and calcitriol reduce NF-κB expression in the aorta and myocardium, with calcitriol showing greater effectiveness than ascorbic acid.
IMPLEMENTASI SISTEM INTEGRASI TERNAK DAN TANAMAN PANGAN UNTUK OPTIMALISASI PEMANFAATAN LAHAN PEKARANGAN Hamny Hamny
Peternakan Abdi Masyarakat (PETAMAS) Vol 2, No 1 (2022): Volume 2, Nomor 1, Juni 2022
Publisher : Departemen of Animal Science, Agriculture Faculty, Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/petamas.v2i1.25996

Abstract

Penerapan sistem integrasi ternak dan tanaman pangan dengan memanfaatkan lahan pekarangan rumah terutama di pedesaan masih sangat rendah, sehingga dibutuhkan peranan perguruan tinggi untuk mensosialisasikan penerapan teknologi tersebut dalam mewujudkan ketahanan pangan. Gampong (Desa) Pinem merupakan salah satu desa yang terletak di Kecamatan Samatiga, Kabupaten Aceh Barat, Provinsi Aceh. Masyarakat Gampong Pinem memiliki lahan pekarangan rumah yang luas yang belum dimanfaatkan secara optimal. Program IbM ini bertujuan untuk merangsang masyarakat melalui kelompok tani dan ternak untuk memanfaatkan lahan pekarangan rumah yang luas agar lebih produktif. Pemilihan budidaya ayam broiler yang dilaksanakan dalam program ini berdasarkan keinginan anggota kelompok ternak Gampong Pinem untuk menghidupkan kembali usaha ayam broiler yang pernah ditekuni dengan memanfaatkan lahan pekarangan rumah untuk menanam tanaman pangan. Pada kegiatan ini dilakukan demplot sistem manajemen pemeliharaan ayam broiler yang baik dan demplot penanaman tanaman pangan di lahan pekarangan rumah. Kotoran ayam broiler yang dipelihara dimanfaatkan sebagai pupuk organik bagi tanaman jagung, bayam dan kangkung. Kegiatan IbM mampu meningkatkan semangat mitra untuk melanjutkan usaha ayam broiler dan tanaman pangan dengan memanfaatkan lahan pekarangan rumah yang luas. Diharapkan kegiatan ini dapat menunjang perekonomian keluarga.
Co-Authors . Nurliana . Zuchri ., Daniel Abdul Harris Abdullah Hamzah Adi Purnawarman, Adi Ahmad Azhari Nopiosi Alfajri Saputra Alfajri Saputra Ali, Ihfan Khaidir Aliman Irfandi Amalia Sutriana Amiruddin A Andi Novita Anugrah Septian Aris Junaidi Ayu Agita Ginting Azhari Azhari Bambang Pontjo Priosoeryanto Boni Anggara Budianto Panjaitan Budianto Panjaitan Chairun Nisa Chika Nahara Ramadhanty Chintya Desfariza Cut Dahlia Iskandar Daniel Daniel Darmawi Darmawi Debby Novita ayumi Dian Masyitha Dian Masyitha Dian Masyitha Dwinna Aliza Ekawati, Wahyu Enitan, Seyi S. Erdiansyah Rahmi Erdiansyah Rahmi Erdiansyah Rahmi Ezy Yulanda Rezki Fachrizal Ambia Fadli A Gani Fadli A. Gani Fadli A. Gani Fadli A. Gani Fadli. A. Gani Fahrezi, Muhammad Gilbran Faisal Jamin Faisal Mustafa Fakhrurrazi Fakhrurrazi Fakhrurrazi Fakhrurrazi Ferllya Adela Putri Firdausi, Nida Khofiya Fitriani Fitriani Fitriani Fitriani Frengki Frengki Gani, Fadli A Gani, Fadli A. Gholib Gholib Gholib Gholib, Gholib Hafizuddin Hafizuddin Hamdani Budiman Hasan, Hafidh Hasriati Hasriati Hendri Hermawan Adinugraha Herlina Dimiati, Herlina Herlina Yuliani Herrialfian Herrialfian I. Djuwita . I.Nasution . Idawati Nasution Idawati Nasution Idawati Nasution Idawati Nasution INDRA RAHMAWATI Isky, Saiful Ismail Ismail Ismail Ismail Ita Djuwita Ita Djuwita Joharsyah J Juli Melia Kamarlis, Reno K. Ketut Adnyane Mudite Khairun Nisa Kimmy Keisha Avrila Rozandi Kusdiantoro Mohamad Lailia Dwi Kusuma Wardhani Lailia Dwi Kusuma Wardhani Lexa Lady Syourin Lidya Elizabeth M. Manik M. Hasan M. Isa M. Isa M. Jalaluddin M. Jalaluddin, M. Mahdi Abrar Mahdi Abrar Mahdi Abrar Makmur, Ali Manfarizah Manfarizah Manfarizah Manfarizah Maryulia Dewi Mudatsir Mudatsir Mudhita Zikkrullah Ritonga MUHAMMAD AGIL Muhammad Hambal Muhammad Hambal Muhammad Iqbal Muhammad Jalaluddin Muhammad Jalaluddin Muhammad Jalaluddin Muhammad Jalaluddin, Muhammad Muhammad Resthu Muhammad Zulfan Mulyadi Adam Mulyadi Adam Mulyadi Adam Mulyadi Adam, Mulyadi Muslim Akmal Muslim Akmal Mustafa Sabri Mustafa Sabri Mustafa Sabri Muttaqien Muttaqien Nabila Latifa Hafizsha Nadia Hanifah Nanda Yulian Syah Nauval Gibran Lubis Noni Zakiah Nurhidayat, Nurhidayat Nussa, Olan Rahayu Puji Astuti Nuzul Asmilia Patrick Flaggellata Prabowo Purwono Putro Primaadhi Abimanyu Satrio Raharjo Rastina Rastina Razali Daud Rinidar R Rinidar Rinidar Ritonga, Mudhita Zikkrullah Ritonga, Mudhita Zikrullah Roslizawaty R Rosmaidar Rosmaidar S. Agungpriyono . Safni Kamal Saputra, Jefri Dwi Savitri Novelina Shinta Mutia RM Siti Aisyah Sri Haryani Sri Wahyuni Sri Wahyuni Sri Wahyuni Sri Wahyuni Sri Wahyuni Sri Wahyuni Sri Wahyuni Srihadi Agungpriyono Sugito Sugito Sugito Sugito Sulasmi Sulasmi Suriadi S Syafruddin S Syafruddin Syafruddin Syakur Syakur Syakur Syakur Syifa Aurelia Devina T. Armansyah T. Armansyah T. Armansyah, TR Tanjung, Fitri Aisah Taufan Hidayat Taufan Hidayat Taufan Hidayat Taufan Hidayat Taufan Hidayat Teti Arabia Teti Arabia Teuku Heriansyah, Teuku Teuku Reza Ferasyi Tongku Nizwan Siregar Triva Murtina Lubis Tuty L. Yusuf Tuty Laswardi Yusuf Tuty Laswardi Yusuf Ummu Balqis W.E. Prasetyaningtyas . Wahono Esthi Prasetyaningtyas Wahyu Eka Sari Wahyuni, Sri Wardhani, Lailia Dwi Kusuma Wasmen Manalu Yulisma, Rika Yusnizar Yusnizar Yusnizar Yusnizar Zainabun Zainabun Zainabun Zainabun Zainabun Zainabun Zainabun, Z Zainuddin Z Zainuddin Zainuddin Zainuddin Zainuddin Zainuddin Zainuddin Zuhrawati Zuhrawati Zuraidawati Zuraidawati