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Journal : Medula

Hiperglikemia Pada Terapi Nutrisi Parenteral Dwi Anjani, Galuh; Junando, Mirza; Oktarlina, Rasmi Zakiah; Himayani, Rani
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1050

Abstract

Hyperglycemia is a condition that often occurs in some patients on parenteral nutrition therapy, both with and without a diagnosis of diabetes mellitus. The incidence of hyperglycemia is closely related to an increase in length of stay and mortality in hospital. This literature review aims to provide an overview of the management of hyperglycemia related to parenteral nutrition therapy. The source search method was carried out using the Google Scholar, Pubmed and Elsevier search engines. The keywords used are management of hyperglycemia, risk factors, parenteral nutrition. Based on the results of the literature review, it was found that several factors trigger the incidence of hyperglycemia, including BMI > 25 kg/m2, advanced age, higher HbA1c, history of type 2 DM, use of glucocorticoid drugs and administration of excess carbohydrates and reduced insulin sensitivity. Several strategies to prevent hyperglycemia are carried out by providing low dextrose, hypocaloric parenteral nutrition, or combining parenteral and enteral nutrition. Providing combined nutrition can improve glycemic control in patients with sufficient endogenous insulin stores. Meanwhile, therapeutic measures need to be given if hyperglycemia persists after preventative strategies are implemented. Therapeutic measures that can be taken include administering insulin intravenously or subcutaneously to patients in stable condition. Alternatively, insulin can be added to the parenteral nutrition mixture. It is important to closely monitor blood glucose levels to reduce the risk of hyperglycemia or hypoglycemia.
Retinopati Diabetik yang Mengancam Penglihatan Oktaryona Trisera; Himayani, Rani; Apriliana, Ety; Yusran, M
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1070

Abstract

Diabetic retinopathy is a progressive microangiopathy characterized by retinal vascular damage and blockage. The global prevalence of diabetic retinopathy is 34.6%. Clinical manifestations in patients with diabetic retinopathy include aneurysms, vein dilation, vitreous hemorrhage, and hard exudates which can affect visual acuity. Progression of diabetic retinopathy can potentially threaten vision and even blindness even though initially there are no severe clinical manifestations. Visual-threatening diabetic retinopathy is classified into severe NPDR, PDR, and all DR with diabetic macular edema. The global prevalence of VTDR is 7.26% and according to research by Sasongko et al (2017) states that 1 in 4 DM patients has a vision-threatening DR condition (VTDR). The best management of DR is prevention in the form of early screening, education, and counseling, especially in DM patients. For patients who have been diagnosed with DR, follow-up treatment, laser, injection, or even surgery, depending on the severity.
Faktor-Faktor Yang Berhubungan Dengan Kejadian Glaukoma Di Rumah Sakit Mata Lampung Eye Center Bandar Lampung Amelia, Erry Rizki; Himayani, Rani; Suharmanto, Suharmanto
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1093

Abstract

Glaucoma is a chronic progressive optic neuropathy characterized by elevated intraocular pressure, cupping of the optic disc and visual impairment with visual field defects. Every year the number of glaucoma is increasing and become the second common cause of blindness. This study aims to determine what factors related to the incidence of glaucoma at the Eye Hospital Lampung Eye Center Bandar Lampung. This study used an analytic observational design with a cross sectional approach. The data used who were sourced from secondary data in the form of medical records that are recorded data were patient characteristics, main complaint, history of hypertension and incidence of glaucoma. This respondents consisted of 134 glaucoma patients who showed the results that most respondents are in the age group >60 years (43.3%), male (53%), had high education status (64,9%), had no history of hypertension (73.1%), the main complaint with visual impairment (59,7%) and the incidence of primary glaucoma type of glaucoma (47.8%) . There were no correlation among age (p = 0,468), gender (p = 0.148), education status (p = 0.116), a history of hypertension (p = 0.259) and main complaint (p = 0.087) with the incidence of glaucoma at Eye Hospital Lampung Eye Center Bandar Lampung. There were no correlation among the characteristic features, history of hypertension and main complaint of glaucoma with the incidence of glaucoma.
Hubungan Usia, Jenis Kelamin, Dan Pekerjaan Dengan Kejadian Dermatofitosis di Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Provinsi Lampung Periode 2017- 2021 Graceciela, Yohana Eva; Anggraini, Dwi Indria; Himayani, Rani; Sibero, Hendra Tarigan
Medula Vol 14 No 6 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i6.1097

Abstract

Dermatophytosis is a dermatophyte fungal infection that attacks keratinized tissues. This disease can be caused by various internal and external factors. The internal risk factors causing dermatophytosis include age, gender, and occupation. In addition to that, this study aimed at determining the relationship between age, gender, and occupation toward dermatophytosis cases. This study used an analytical observational design with a cross-sectional approach. The sample in this study consisted of 114 patients with dermatophytosis sourced from the secondary data in the form of medical records. The research data were conducted by using total sampling technique in RSUD Dr. H. Abdul Moeloek Lampung Province. The recorded data included the patients’ age, gender, occupational, and diagnosis. Then, the data were analysed using chi-square test presented in tabular form. The results showed that the majority of dermatophytosis patients were adults, female, and employees who worked in government/private institutions. The results of the chi-square test showed a significant value for the age variable (p = 0.035) and the gender variable (p = 0.041), while for the work variable there was no significant relationship (p = 0.615). There is a significant relationship between age and gender with the dermatophytosis cases and there is no significant relationship between occupation and the dermatophytosis cases.
Trakoma: Penyakit Tropis Terabaikan Ghiffari, Fahman; Himayani, Rani
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1107

Abstract

Trachoma is a neglected tropical disease. Trachoma is an infection of the eye caused by bacteria Chlamydia trachomatis. This disease often attacks people who live with low economic income with a bad environment. This infection is transmitted through physical contact and from animals to humans. Trachoma can be classified into an active or infectious phase and a chronic or non-infectious phase. According to its level, trachoma has six types of grades in the assessment of clinical symptoms of trachoma namely stage Normal Tarsal Conjunctiva (N), stage Trachomatous inflammation-Follicular (TF), stage Trachomatous inflammation-Intense (OF), stage Trachomatous Scarring (TS), stage Trachomatous Trichiasis (TT), and stage Corneal Opacity (CO). Treatment that can be done to treat trachoma is the SAFE program developed by WHO, including: surgery (surgery),antibiotics (antibiotics),facial cleanliness (facial cleansing), and environmental improvement (environmental improvement). This article uses the method literature review from various national and international journal references with the following search keywords: trachoma, etiology, classification, management, and Chlamydia trachomatis.
HUBUNGAN ANTARA PEMBERIAN KOLOSTRUM, ASI EKSKLUSIF, DAN USIA PENYAPIHAN DENGAN KEJADIAN STUNTING PADA ANAK BADUTA USIA 12-23 BULAN (ANALISIS RISKESDAS 2018) Chindy Annisa Putri Mandala Sempaga; Sutarto; Rani Himayani
Medula Vol 14 No 6 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i6.1146

Abstract

The prevalence of stunting in Indonesia was 37.2% in 2013, 30.8% in 2018, and 27.67% in 2019. The number of stunting was indeed decreasing, but based on World Health Organization standards, the prevalence of stunting in a country is classified as high if it exceeds 20%. This shows that the prevalence of stunting in Indonesia is still high. Inadequate breastfeeding practice in the first 1.000 days of life is one of the factors that play a role in the incidence of stunting. This research is an analytic study with a cross sectional approach. The sample used comes from secondary data from Riskesdas 2018 with a total samples of 36,259. The dependent variable is the incidence of stunting and the independent variable consists of colostrum administration, exclusive breastfeeding, and weaning age. Data analysis was performed by bivariate test using chi-square. The results showed that there was a significant relationship between colostrum administration (p-value = 0.009), exclusive breastfeeding (p-value = 0.001), and weaning age (p-value = 0.001) with the incidence of stunting in children under the age of 12- 23 months. There is a significant relationship between colostrum administration, exclusive breastfeeding, and weaning age with the incidence of stunting in children under two years old aged 12-23 months. The risk factors for exclusive breastfeeding and weaning age have the same influence on the incidence of stunting in children under two years old aged 12-23 months in Indonesia.
Infeksi Protozoa Usus dan Anemia Sebagai Ancaman Kesehatan Global: Literature Review Rahmah, Nisrina Nur; Mutiara, Hanna; Septiani, Linda; Himayani, Rani
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1291

Abstract

Intestinal protozoan infections are a global health issue that needs to be monitored due to the high morbidity and mortality rates, particularly in areas with poor hygiene and sanitation. Intestinal protozoan infections are diseases caused by protozoan parasites, which are single-celled eukaryotic microorganisms generally classified under the Kingdom Protista. The most frequently reported intestinal protozoa species responsible for human infections are Blastocystis hominis, Cryptosporidium parvum, and Giardia lamblia. There are two key factors contributing to the occurrence of intestinal protozoan infections: individual and environmental factors. Intestinal protozoan infections are known to cause various harmful consequences, particularly regarding the nutritional status of the affected individuals. As a result, intestinal protozoan infections are often associated with iron deficiency anemia, which can ultimately disrupt growth and development in children and decrease productivity in adults. This study aims to identify the pathways through which intestinal protozoan infections cause iron deficiency anemia. The study method involved a literature review and problem analysis. The results indicate that there are three main pathways through which intestinal protozoan infections lead to iron deficiency anemia: the metabolism of pathogenic microorganisms within the human body, the activation of the immune response to pathogenic microorganisms, and the reduction in micronutrient levels. To prevent these infections, the public is advised to improve personal hygiene, such as regularly washing hands, and to enhance environmental sanitation by treating water through filtration or disinfection.
Tinjauan Pustaka : Kebiasaan Merokok dan Paparan Ultraviolet Sebagai Faktor Risiko Katarak Senilis Ghaitsa Lulua; Himayani, Rani; Septiani, Linda; Berawi, Khairunnisa
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1419

Abstract

Cataract ranks second as the most common visual impairment and first as a cause of blindness, as the lens hardens and causes a decrease in sharp vision. Based on age, cataracts are divided into several types: congenital cataract, juvenile cataract and senile cataract. Senile cataract is a cataract that often occurs in older people. The classification of senile cataracts is based on the progression of the cataract's opacity, namely, incipient, immature, mature, and hypermature. Some of the risk factors for senile cataracts include a history of diabetes mellitus, family history, smoking, and exposure to ultraviolet light. Smokers have a higher risk of developing senile cataracts than non-smokers. Ingredients in cigarettes such as cyanate, nicotine and tar can cause changes and denaturation of proteins in the lens of the eye. Meanwhile, sunlight absorbed by the eye produces free radicals and affects the tissues in the lens of the eye, triggering oxidative reactions, causing changes in amino acid reactions and leading to senile cataracts.
Kelainan Genetik Pada Down Syndrome Cahyana, Adinda Husna; Syachrani , Fayza; Maharani , Mentari Putri; Himayani, Rani; Rahmanisa, Soraya
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.926

Abstract

Down syndrome (SD) is a common and easily recognized genetic disorder. In the genetic disorder trisomy or SD, there is an extra chromosome on chromosome 21. This chromosome causes the production of certain proteins in excessive amounts, thus disrupting the normal growth of the organism and causing changes in brain development. The estimated incidence of SD is one in 800-1000 births. The incidence of SD in the world is 10 per 10,000 live births, and in recent years this figure has increased. The World Health Organization (WHO) estimates that there are around 8 million SD sufferers worldwide. In Indonesia itself, the prevalence of SD is 1 per 600 live births. Down syndrome is a condition where the sufferer has retarded physical and mental development due to abnormal chromosome development. Chromosomes contain genetic material that determines human characteristics, so that some children with Down syndrome will usually experience mental disabilities, whether mild or moderate.
The Effectiveness of Phacoemulsification in Cataract Management: Procedures, Benefits, and Challenges Nurhaliza, Rahma; Himayani, Rani; Febriani, Wiwi; Rudiyanto, Waluyo
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1278

Abstract

Cataract is a condition in which the eye's lens, initially clear becomes cloudy, obstructing the passage of light to the retina and causing vision impairments such as blurred vision, reduced visual acuity, and faded color perception. According to WHO data (2022), approximately 2.2 billion people worldwide experience visual impairment, with cataracts being the leading cause of reversible blindness. In Indonesia, the prevalence of cataracts is 1.8%, with an annual incidence rate of 0.1%, and 50% of blindness cases are caused by cataracts. Surgery is the only method to treat cataracts, with phacoemulsification being the most commonly used technique. Phacoemulsification is a cataract surgery technique that employs an ultrasonic tip to break down the cloudy lens, followed by aspiration of the lens fragments. This technique has numerous advantages, including smaller incisions, faster wound healing, good visual acuity outcomes post-surgery, and a lower risk of complications than other surgical methods.
Co-Authors Ad-Dhuha, Rahmah Maziyah Adelia, Anggi Adrifianie, Femmy Ahmad Duta Al-Ihya Alfina Indah Nabila Amalia Febriyanti Ambarwati, Endah Amelia, Erry Rizki Amira Nabila Andrifianie, Femmy Angelica Philia Christy Anggraeni Janar Wulan Anindia Syafia Halimathus Sa'dyah Aprianti, Shervia Dwi Ardella, Karina Belinda Ardika, Okta Besti ari wahyuni Ari Wahyuni Ari Wahyuni Arif Yudho Prabowo Asep Sukohar Betta Kurniawan, Betta Brigitta Shinta dewi Cahyana, Adinda Husna Carissa Aprilia Y Chindy Annisa Putri Mandala Sempaga Cut Karel Dithia Daffa Fahreiza Damayanti, Ervina Devina Hardianto Devira Fitriani Kamal Dewayanti, Wahyu Dwi Anjani, Galuh Dwi Indria Anggraini Edward Sintong Samosir Ellysa Angguman Putri Ety Apriliana Ety Apriliana Evan Christian Christian Fadhilah, Fuad Fadilah Alwiyah Fairuz Hanan, Sifa’Syaharani Faisal Rohmadhiyaul Haq Faisol Rohmadhiyaul Haq Faridi Pani Farraz Kanya Syahra Fauzan Hafizh, Ahmad Fauziani, Andra Nabila Fayza Syachrani Febri Nadyanti Febrianti, Arlin Fernadya Sylvia Nurindi Firsandini, Firsandini Fitria Saftarina Ghaitsa Lulua Ghifari, Ghaza Ahmad Al Ghiffari, Fahman Ghina Salsabila Fenty PNR Gigaramadan Sema Gigih Forda Nama Giska Tri Putri Graceciela, Yohana Eva Hana Qanitah Hanifah Qollama Astrid Hanna Mutiara, Hanna Happy, Terza Aflika Helmi Ismunandar Helmi Ismunandar Hendra Tarigan Sibero Hery Dian Septama Ida Laila Ihsanti Dwi Rahayu Ika Agustin Putri Haryant Imtinan Khoirunnisa Intan Kusumaningtyas Intanri Kurniati Junando, Mirza Junita, Aulia Kadek Elvina Kusuma Putri Kamila Nastiti Keziah Tirtawijaya Khairun Nisa Kurnia Fithrananda Kurniawan, Diva Ardhana Lintang Lestari Cahya Sawitri Lubna Farhana M Yusran M. Revo Artmando L M. Yusran Maharani , Mentari Putri Mallarangeng, Andi Nafisah Tendri Adjeng Mardiana Mardiana Maretta, Alvina Christy Maureen Angelica Melni Armadani Mentari Putri Maharani Mochamad Fauzan Dava Muhammad Aditya, Muhammad Muhammad Arsy Kamal Faadhil Muhammad Maulana Muhammad Maulana Muhammad Yusran Muhartono Muhartono Mukhlis Imanto Nabila Alsa Sagia Nabila Rayhan Yasmin Nadhia Wihelga Nahrassyiah Rahma Putri Naila Fathiya Isnanto Nashwa Faadillah Nasyim Natanael, Jessica Neli Salsabila Ni Made Karenina Rini Dwi Cintawan Noval Ramadirta Nur Fadillah, Astri Nurhaliza, Rahma Nurul Fadhilah Az-zahro Nurul Purna Mahardika Nurul Utami Okki Muhammad Fajar Muthahhari oktadiani, Isna Oktafany, Oktafany Oktaryona Trisera Oktoba, Zulpakor Prayogi, Norbertus Marcell Putu Ristyaning Ayu RA Genta Syakira Hatta Rachel Agustin Inggrid Zefanya Rahmah, Nisrina Nur Ramadhan Triyandi Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rasmi Zakiah Oktarlina Regita Dwi M Rekha Nova Iyos, Rekha Nova Rengganis Wardani, Dyah Wulan Sumekar Renitta Anggraeni Rifka Putri Dewi Riska Azzahra Risti Graharti Ristyaning Ayu Sangging, Putu Rizki Hanriko Rizqiani Astrid Nasution Rudiyanto, Waluyo Ruth Leria Noverika Salsabila Haqya Kusuma Sangging, Putu Ristyaning Ayu Saphira Murfi Septiani, Linda Serafina Subagio Shifa Azzahra, Nimas Sitanggang, Grety Soraya Rahmanisa Suharmanto Susanti, Andani Dewanti Sutarto Sutarto Sutarto Sutarto Syachrani , Fayza Syahrani Alya Murfi Syazili Mustofa Syiva Ulhayah T. Adjeng, Andi Nafisah Thamara Az Zahra Tri Umiana Sholeha Tri Umiana Soleha Tri Umiana Soleha Tsurayya Fathma Zahra Vania Widyadhari Damayanti Widjaja, Jovan Wildan Kautsar Irawan Wiwi Febriani Yashila Rahimah Yasmin, Deffina Widya Yuliant, Titin Yusran, M Zenith Puspitawati Zheva Aprillia Yozevi