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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Brawijaya Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Degraded and Mining Lands Management Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Majalah Kedokteran Sriwijaya Sari Pediatri Biomedical Journal of Indonesia Paediatrica Indonesiana Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Alami Journal (Alauddin Islamic Medical) Journal Sainmatika: Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat SRIWIJAYA JOURNAL OF MEDICINE Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research JURNAL MEDIA KESEHATAN Best Journal (Biology Education, Sains and Technology) MDJ (Makassar Dental Journal) Sriwijaya Journal of Surgery Indonesian Journal of Global Health research Jurnal Menara Medika Bioscientia Medicina : Journal of Biomedicine and Translational Research International Journal of Islamic and Complementary Medicine Indonesian Community Journal Journal of Anesthesiology and Clinical Research Sanitasi: Jurnal Kesehatan Lingkungan AKSONA Conferences of Medical Sciences Dies Natalis Jurnal Sehat Indonesia (JUSINDO) Indonesian Journal of Biomedicine and Clinical Sciences
Irfannuddin Irfannuddin
Faculty Of Medicine, Universitas Sriwijaya
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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DIFFERENCES OF SHORT-TERM CONSUMPTION OF SEMENDO ROBUSTA AND ARABICA COFFEE TOWARDS SWEET TASTE SENSITIVITY Pudi Handayani; Irfannuddin Irfannuddin; Alifia Salsabila; Shanty Chairani; Nursiah Nasution
JURNAL KEDOKTERAN DAN KESEHATAN Vol 10, No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V10I2.20924

Abstract

The most consumed and cultivated coffee in Indonesia is robusta and arabica coffee. Robusta and arabica coffee have different characteristics such as morphology, contents, and taste. Coffee consumption could cause alteration in taste sensitivity, especially sweet taste. Those could affect daily sugar consumption. The present study aimed to determine the differences of short-term consumption of semendo robusta and arabica coffee towards sweet taste sensitivity. This study used experimental study with a cross-over design approach that involved 21 students from the Faculty of Medicine Sriwijaya University. Semendo robusta and arabica coffee are used in this study. Sweet taste sensitivity was tested using the whole mouth test method by rinsed with sucrose solution at a concentration of 0,16, 0,32, 0,64, and 1,28 mol/l, which was given from the lowest concentration. Sweet taste sensitivity scores were rated at baseline and after the consumption of semendo robusta and arabica coffee which took place on different days. The lowest sucrose concentration that was correctly interpreted by the subject was noted as a taste sensitivity score. Data were analyzed using the Chi-square test. The chi-square test showed that the decrease in sweet taste sensitivity was more frequently happening after semendo arabica coffee consumption than semendo robusta coffee consumption (p<0,05). Short-term consumption of semendo arabica coffee has significantly increased the risk of sweet taste sensitivity reduction 4 times greater than semendo robusta coffee. There were differences in sweet taste sensitivity between short-term consumption of semendo robusta and arabica coffee.
Sensitivity and Specificity of Ultrasonographic Compared with CT Angiography in Detecting Femoropopliteal and Infrapopliteal Arterial Lesions in Lower Extremity Arterial Disease in Dr. Mohammad Hoesin General Hospital Palembang Radi Noorsyawal; Kemas Dahlan; Hanna Marsinta; Irfannuddin
Sriwijaya Journal of Surgery Vol. 4 No. 1 (2021): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v4i1.55

Abstract

Background: Peripheral artery disease (PAD) is a chronic occlusive arterial disease of the extremities caused by atherosclerosis.1 It is estimated that 20-30% of the population worldwide suffered PAD.2 PAD is associated with a 1-year mortality and limb loss rate of 20%.7 Critical limb ischemia (CLI) is a late stage clinical presentation of PAD. Imaging of the entire artery is possible using CT angiography. However, CT angiography has its drawbacks because the contrast used can be nephrotoxic, the risk of allergies, expensive, and not all health services have it. Ultrasonographic’s (USG) sensitivity, specificity and accuracy were 96.55%, 61.53%, and 78.84% for detecting lower limb distal artery lesions.11 Ultrasonographic does not require the use of contrast, radiation, low cost and almost all health services have them.12 However, the Ultrasonographic examination has its limitations depending on the operator's capabilities. It is therefore necessary to conduct research that have never been previously studied in South Sumatra. Methods: This study is a diagnostic test study that examines the sensitivity and specificity of ultrasound in detecting LEAD artery lesions. The samples were 29 patients. Results: At the femoropopliteal level, the results obtained were 91% sensitivity and 86% specificity. At the infrapopliteal level, the results obtained were 95% sensitivity and 87% specificity. Conclusion: Ultrasonographic has high sensitivity and specificity in detecting LEAD’s lesions
Efek Puasa Terhadap Biomarker Hepar : Sebuah Tinjauan Pustaka Sistematis Anggraini, Wieke; Irfannuddin, Irfannuddin; santoso, budi; Sinulingga, Sadakata; Zulissetiana, Eka Febri; Nurwany, Raissa
Syifa'Medika Vol 15, No 1 (2024): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v15i1.8773

Abstract

Terdapat berbagai penelitian yang melihat dampak puasa sebagai intervensi diet yang untuk menurunkan berat badan, menurnkan hemoglobin terglikosilasi, menurunkan risiko aterogenik, meningkatkan sirkulasi sitokin dan proliferasi sel imun. Tinjauan ini bertujuan untuk melihat penelitian terkait puasa dalam menurunkan inflamasi. Tinjauan ini disusun sesuai dengan algoritma PRISMA yang melibatkan 31 kepustakaan yang dikumpulkan dari Pubmed maupun EuropePMC. Tinjauan ini menemukan bahwa puasa dapat mengurangi inflamasi yang ditandai dengan berbagai biomarker. Oleh karena itu puasa dapat menjadi salah satu intervensi diet yang dapat bermanfaat bagi kesehatan jika dilakukan dalam jangka waktu yang lama dan secara konsisten
The Potential of Shell Extract as a Hemostasis and Wound Healing Agent: A Literature Review Erlyn, Putri; Irfannuddin, Irfannuddin; Murti, Krisna; Lesbani, Aldes
Jurnal Kedokteran Brawijaya Vol. 33 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2023.033.01.6

Abstract

Hemostasis is an emergency medical treatment to reduce pain and patient mortality, therefore research is being developed to find effective hemostasis. The utilization of natural materials for hemostasis and wound healing is rapidly expanding, including chitosan found in shell extracts. Chitosan is obtained from chitin found in the soft shells of marine animals such as squid, shrimp, and crabs, or from hard shells such as clams, crabs, and lobsters. Chitosan offers advantages such as good biodegradability, biocompatibility, and non-toxicity, and has been widely used in biomedical, chemical, food, and cosmetic industries. This literature review aims to investigate the potential of shell extracts, particularly the characteristics of chitosan, in wound healing across hemostasis, inflammation, proliferation, and remodeling stages. The study results indicate that extracts from shells containing chitosan exhibit varying characteristics in terms of molecular weight and degree of deacetylation. Chitosan with higher molecular weight and degree of deacetylation tends to yield better outcomes in hemostasis and wound healing. The material is effective in reducing antithrombin, enhancing blood clotting processes, and aiding clot formation. Increased molecular weight contributes to stimulating various cytokines, such as TNF-α, TGF-ß1, and FGF2, which play a key role in the wound healing process. Additionally, higher degree of deacetylation chitosan is effective in stimulating fibroblast proliferation. Chitosan also influences VEGF in inducing angiogenesis and enhancing neovascularization in bone healing. Chitosan from shell extracts with certain molecular weight characteristics and degree of deacetylation has the potential to be the material of choice for accelerating hemostasis and wound healing.
Determination of mercury in soil and water from a gold mining area in Karang Jaya Sub-district, Musi Rawas Utara, Indonesia Amallia, Ra Hoetary Tirta; Ibrahim, Eddy; Irfannuddin, Irfannuddin; Hariani, Poedji Loekitowati
Journal of Degraded and Mining Lands Management Vol. 11 No. 2 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15243/jdmlm.2024.112.5375

Abstract

The present study focuses on the assessment of Hg distribution in both soil and water samples from the small-scale gold mining region of Karang Jaya Sub-district, Musi Rawas Utara Regency, South Sumatra Province. For over 30 years, this region has witnessed persistent utilization of mercury as an amalgam for gold extraction. The investigation encompasses an analysis of total mercury levels in soil samples obtained from Sukamenang, Muara Batang Empu, and Terusan Villages. As a comparative reference point devoid of gold mining activities, the neighboring Muara Lakitan Village was selected. The obtained results indicate a moderate to strong contamination level across the 30 sampled locations based on the Geoaccumulation Index (Igeo), with an average Igeo value of 2.6. Furthermore, Pollution Load Index (PLI) and Contamination Factor (CF) values demonstrate high contamination. Conversely, analysis of river water samples from 30 stations along the Rupit River reveals that most of the samples comply with quality standards (<0.0005 mg/L), with an average value at 0.000322 mg/L; only four stations exhibit total Hg concentrations surpassing regulatory thresholds. All soil and river water samples from the control area (10 stations) exhibited no signs of pollution. Appropriate investments in technology, finance, and technical skills are needed to reduce mercury pollution due to small-scale gold mining activities.
Bioinformatics analysis and biomolecular characterization of salivary alpha amylase as risk factor for dental caries: Analisis bioinformatika dan karakterisasi biomolekuler alfa amilase saliva sebagai faktor risiko karies gigi Dewi, Siti Rusdiana Puspa; Irfannuddin
Makassar Dental Journal Vol. 13 No. 2 (2024): Volume 13 Issue 2 Agustus 2024
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v13i2.1035

Abstract

Salivary alpha amylase is a component in human saliva that plays important role in carbohydrate digestion. This article aims to analyze bioinformatics and biomolecular characterization of salivary alpha amylase as risk factor of dental caries. The location of this gene is 1p21.1, with nucleotide is NC_000001.11. This information was taken from National Center for Biotechnology Infor-mation's website. The number of amino acids of salivary alpha amylase is 511, with molecular weight is 577,677.82 amu. The pro-tein is stable with instability index is computed to be 23.58. Only 23 enzymes were predicted to be capable of cleaving the sa-livary alpha amylase out of a total of 37 protease. The aliphatic index is 67.12. From THMM analysis, salivary alpha amylase is found outside of membrane. It is concluded that characteristic of salivary alpha amylase can be considered as indicator for caries.
Studi Meta-Analisis: Hubungan antara Defisiensi Vitamin D dan Penyakit Parkinson Putri, Siti Sarahdeaz Fazzaura; Irfannuddin, Irfannuddin; Murti, Krisna; Kesuma, Yudianita; Koibuchi, Noriyuki
Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Vol 9, No 1 (2023): JMK Yayasan RS.Dr.Soetomo, Pertama 2023
Publisher : STIKES Yayasan RS.Dr.Soetomo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29241/jmk.v9i1.1430

Abstract

Beberapa penelitian telah dilakukan untuk mengevaluasi kadar 25(OH)D pada pasien penyakit Parkinson. Namun, hasil penelitian ini tidak konsisten. Penelitian ini melakukan meta-analisis terhadap kadar 25(OH)D pada pasien dengan penyakit Parkinson. Database PubMed digunakan untuk melakukan pencarian literatur secara sistematis. Meta-analisis dilakukan dengan menggunakan model efek acak untuk menghitung perkiraan efek gabungan. Tujuh belas artikel dimasukkan dalam penelitian ini. Meta-analisis mengungkapkan bahwa pasien dengan penyakit Parkinson memiliki kadar 25(OH)D yang lebih rendah dibandingkan dengan kontrol. Temuan dari artikel prospektif dan retrospektif sebagian besar konsisten. Besarnya respon nocebo dalam uji coba terkontrol acak yang dirancang paralel pada penyakit Parkinson sangat penting dan harus dipertimbangkan dalam interpretasi hasil keamanan dan dalam desain dan interpretasi uji klinis masa depan. 
Walking as a Modality for Enhancing Physical Fitness: A Review Rachel Maya; Irfannuddin; Siti Sarahdeaz Fazzaura Putri
Sriwijaya Journal of Medicine Vol. 7 No. 2 (2024): Vol 7, No 2, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v7i2.258

Abstract

Walking plays a key role in maintaining overall physical fitness which is essential for good health. Physical fitness consists of two main aspects health-related and skill-related components. It is commonly measured by assessing cardiovascular endurance muscle strength muscle endurance flexibility and body composition. This review conducted a comprehensive literature search using reputable publications such as Elsevier, PubMed, PubMed Central, and other relevant sources. The search focused on peer-reviewed studies that examine the effects of walking on physical fitness. Many studies highlight walking as a simple and accessible form of exercise that offers significant benefits such as improved cardiovascular endurance muscle strength and flexibility. It is recommended to engage in at least 150 minutes of walking each week for optimal benefits. To maximize walking's impact on fitness it is crucial to maintain good posture and proper breathing techniques. In addition to physical benefits walking also promotes mental and social well-being. It is a versatile activity suitable for all ages including adolescents, adults, children, seniors, and individuals with specific health conditions or diseases. By understanding the connection between walking and fitness people can incorporate it into their daily routines to enhance overall health. Future research could focus on specific fitness aspects related to walking to develop personalized guidelines for different populations.
Preliminary Study on the Measurement of Cadmium Levels in Scavenger Hair at Sukawinatan Landfill Palembang Panca Putri, Yunita; Irfannuddin; Daniel Saputra; Suheryanto
Sainmatika: Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam Vol. 21 No. 2 (2024): Sainmatika : Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam
Publisher : Universitas PGRI Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31851/sainmatika.v21i2.17058

Abstract

Cadmium (Cd) is a toxic heavy metal with the potential to contaminate the environment, particularly in landfill sites using open dumping systems, such as the Sukawinatan Landfill in Palembang. This study aims to measure Cd levels in scavengers’ hair as an indicator of heavy metal exposure. A cross-sectional study design was conducted in January 2024, with hair samples collected from five respondents using purposive sampling techniques. Cd levels were measured using the Atomic Absorption Spectrophotometry (AAS) method. The results showed that Cd levels in the scavengers' hair ranged from 0.31 to 0.99 ppm, exceeding the normal limit set which is <0.10 ppm. The duration of work as a scavenger was identified as the dominant factor influencing Cd levels, although anomalies were observed in younger scavengers with high exposure intensity. These findings suggest that the working environment at the landfill significantly contributes to the accumulation of Cd in the body. This study provides preliminary insights into the health risks faced by scavengers at the Sukawinatan Landfill, which can serve as a basis for developing policies and mitigation measures to improve scavengers' occupational health and safety.
Novel Insights into the Pathophysiology of Coronary Slow Flow Phenomenon: The Role of Triglycerides-Glucose Index and Electrocardiogram Risk Score in Subclinical Atherosclerosis Kusuma, Singgih; Erwin Sukandi; Taufik Indrajaya; Ferry Usnizar; Irfannuddin
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i3.1228

Abstract

Background: Coronary slow flow phenomenon (CSFP) is characterized by delayed distal coronary vessel opacification without significant epicardial coronary stenosis. The underlying mechanisms of CSFP remain unclear, but subclinical atherosclerosis is a likely contributor. This study investigated the relationship between the Triglycerides-Glucose Index (TyG), Electrocardiogram Risk Score (ERS), and carotid intima-media thickness (CIMT) in CSFP patients. Methods: This cross-sectional study involved 31 patients diagnosed with CSFP at Dr. Mohammad Hoesin General Hospital Palembang. CSFP was determined based on coronary blood flow slowdown on angiography. Data collection included anamnesis, physical examination, laboratory tests, echocardiography, and CIMT measurement. Statistical analysis was performed using SPSS 27. Results: The majority of CSFP patients were male (51.6%) with a mean age of 50.87 ± 13.94 years. Dyslipidemia was the most prevalent risk factor (77.4%), followed by hypertension (35.5%), smoking (22.6%), and diabetes mellitus (6.5%). Statistical analysis revealed significant positive correlations between TyG index and CIMT (r = 0.445, p = 0.012), and between ERS and CIMT (r = 0.476, p = 0.007). Conclusion: TyG and ERS indices are positively correlated with CIMT in CSFP patients. These indices may be useful tools for cardiovascular risk evaluation and early identification of high-risk patients for subclinical atherosclerosis and potential CSFP.
Co-Authors Ahmad Junaidi Ahmadi Ahmadi Aini, Lela Aldes Lesbani Aldiar Ali Ghanie Alifia Salsabila Amallia, RA Hoetary Tirta Andi Miarta Andi Saputra Andi Saputra Andika Okparasta Andini Agustina Anggraini, Wieke Ardesy Melizah Kurniati Arwan Bin Laeto Budi Santoso Citra Maharani Dahlan, Kemas Daniel Saputra Dewi Susan Diansari, Yunni Dwi Budi Santoso Eddy Ibrahim Eddy Mart Salim, Eddy Mart Eka Febri Zulissetiana Eka Febri Zulissetiana Elsafani Faddiasya Erni Desmita Erwin Sukandi Erwin Sukandi Esa Indah Ayu, Esa Indah Fachmi Idris Fajarini, Agustina Fatmawati Fatmawati Febian Aji Wicaksono FERLY OKTRIYEDI Ferry Usnizar Fredi Heru Irwanto Geo Vanda Ghina Kartika Handayani, Sri Hanna Marsinta Hestiningsih, Tyas Huntari Harahap Husodo, Reyki Yudho Iche Andriyani Liberty, Iche Andriyani INDRA FRANA JAYA KK Indriyani Indriyani Jayawarsa, A.A. Ketut Karmila, Ariesti Kemas Dahlan Koibuchi, Noriyuki Krisna Murti Kusuma, Singgih Legiran Legiran Lela aini Lestari, Ajeng dwinta Lilik Pranata M. Hatta Dahlan M. Hatta Dahlan Mailan Alexander Mariana Mariana marisdina, selly Masagus Irsan Saleh Masayu Rita Dewi Masayu Rita Dewi Maya, Rachel Medina Athiah Mega Gemala Miftahurrahmah Miftahurrahmah, Miftahurrahmah Minerva Riani Kadir Monica, Ricca Muhammad Hatta Dahlan Muhammad Irsan Saleh Mukhlisa Mukhlisa, Mukhlisa Muradi, Akhmadu Nadia Mutiara Ngudiantoro . Nur Rachmat Lubis Nursiah Nasution Nursiah Nasution Nursiah Nasution, Nursiah Nurwany, Raissa Oktarizal, Hengky Pahrul, Dedi Patiyus Agustiansyah Poedji Loekitowati Hariani Pudi Handayani Putri Erlyn Putri, Sarahdeaz Siti Fazzaura R.Kintoko Rochadi Rachel Maya Raden Muhammad Indra Radi Noorsyawal Radiyati Umi Partan Ramadhoni, Pinto Desti Rini Nindela Rini Yana Risa Vera, Risa Rizal Sanif Roni Saputra Sadakata Sinulingga Safri Dhaini Safyudin Shanty Chairani Sintiya Halisya Pebriani Siti Nurmaini Siti Rusdiana Puspa Dewi Siti Sarahdeaz Fazzaura Putri Subandrate Suheryanto Suprapti Suprapti Susanty, Tri Susilawati Susilawati Susilawati Susilawati Swanny Swanny, Swanny Syahputri, Rizka Aprillia Syarif Darwin Tanzila, R.A Tanzila, Raden Ayu Taufik Indrajaya Taufik Indrajaya Tri Suciati Trijoso Permono Trinovita Andraini Yenny Febriany Yuanita Windusari Yudhie Tanta Yudianita Kesuma, Yudianita Yunita Fediani Yunita Fediani Yunita Panca Putri, Yunita Yusuf Effendi Yususf, Fahmi Jaka Zaky Hasan Zulkarnain, Mohammad Zulkhair Ali Zulkifli