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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA MEDIA KONSERVASI Hemera Zoa Jurnal Sain Veteriner Jurnal Veteriner JURNAL ANATOMI FISIOLOGI Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter BIOTROPIA - The Southeast Asian Journal of Tropical Biology Jurnal Peternakan Indonesia JITRO (Jurnal Ilmiah dan Teknologi Peternakan Tropis) Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Bioma : Jurnal Biologi Indonesia Buletin Anatomi dan Fisiologi (Bulletin of Anatomy and Physiology) ARSHI Veterinary Letters FITOFARMAKA: Jurnal Ilmiah Farmasi EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup JFIOnline Jurnal Ilmu Kefarmasian Indonesia JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Aisyah : Jurnal Ilmu Kesehatan Journal of Parasite Science Jurnal Kedokteran Hewan Jurnal Veteriner Nusantara
HERA MAHESHWARI
IPB University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Engineering Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Public Health Veterinary Other

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Potency of Bioactive Compound of Cassava Leaf Paste to Support Physiological Performance of Quail Jumadin, La; Maheshwari, Hera; Ulupi, Niken; Satyaningtijas, Aryani Sismin
Jurnal Ilmu dan Teknologi Peternakan Tropis Vol 9, No 2 (2022): JITRO, May
Publisher : Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (469.622 KB) | DOI: 10.33772/jitro.v9i2.21278

Abstract

Cassava leaf paste is an alternative substance in supporting the physiological performance of quail. Cassava leaf paste contains nutritional compositions such as water, ash, crude protein, crude fiber, fat, and carbohydrate. Cassava leaf paste has high crude protein and low crude fiber. The content of β-carotene and chlorophyll in cassava leaf paste has the ability as an antioxidant. Cassava leaf paste also contains phytochemicals such as flavonoids, saponins, tannins, sitosterol, and stigmasterol. The concentration of phytochemical has slightly higher flavonoid content, moderate tannins and saponins, and high sitosterol and stigmasterol. These phytochemicals act as antioxidants, antimicrobials, anti-inflammatory, improve the immunomodulatory system and reduce cholesterol. In addition, cassava leaf paste contains macro minerals such as P and Ca, as well as microminerals (Fe, Cu, Mn, and Zn). These minerals act as an antioxidant increases nutrient absorption, enhances immune response, and take part in mineralization during eggshell formation. Cassava leaf paste also has low levels of cyanide. Based on the nutritional content, phytochemicals, macro and micro minerals, and cyanide acid, cassava leaf paste has the potential to increase the physiological performance of quail.
Imunitas dan Produktivitas Puyuh Periode Bertelur dengan Pemberian Tepung Daun Senduduk (Melastoma malabathricum L.) dalam Pakan Dawanto, Jirfan; Ulupi, Niken; Maheshwari, Hera
Jurnal Ilmu Pertanian Indonesia Vol. 29 No. 3 (2024): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18343/jipi.29.3.356

Abstract

Senduduk leaf flour (Melastoma malabatricum L.) is a processed product from weed plants that can potentially be a source of nutrients and bioactive compounds that are beneficial for human and livestock health. This research aims to examine the immunity and productivity of quail during the egg-laying period by administering senduduk leaf flour. This study used 120 female quail aged 40 weeks, which were kept for 4 weeks. The experimental design used was a Completely Randomized Design. The treatment of providing senduduk leaf flour in feed consisted of four treatment levels, namely P0 (without flour), P1 (feed + 1.5% flour), P2 (feed + 3% flour), and P3 (feed + 4.5% flour). The data were analyzed using Analysis of Variance and descriptive analysis. The results showed that adding senduduk leaf meal can reduce egg yolk cholesterol and increase quail immunity. Adding senduduk leaf meal at a 3% level produced the best immunity and performance, with a feed conversion value of 2.81. The 4.5% addition of senduduk leaf flour produced the lowest cholesterol level in quail egg yolk. Keywords: egg quality, immunity, performance, quail, senduduk leaf
PENGARUH SUHU TERHADAP DIFERENSIAL LEUKOSIT SERTA KADAR MALONDIALDEHIDE (MDA) BURUNG PUYUH (Coturnix coturnix Japonica) Maheshwari, Hera; Sasmita, Annissa Nuridfi; Farajallah, Achmad; Achmadi, Pudji; Santoso, Koekoeh
Bioma Vol. 13 No. 2 (2017): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.533 KB) | DOI: 10.21009/Bioma13(2).4

Abstract

The main problem in tropical poultry farming that often happens is a high mortality rate. Deaths occurrance mostly by heat stress, a condition which is caused by high temperature ( > 28 ° C). Prolonged heat stress was given to 24 quails grouped in four groups: A (39 ° C), B (41 ° C), C (43 ° C) and D (45 ° C). Provision of heat stress was done when the quails were 2 days old. Blood sampling was performed at the age of 6 weeks. Overall, there was an increase in the number of white blood cell, heterophile, eosinophil, monocyte, the ratio between heterophyll and lymphocyte and malondialdehyde (MDA) levels in all treatment groups. While the number of lymphocytes decreased in all treatment groups. Basophils had a significant increase in group C, but there was a decrease in group B and D decreased from control. This indicates that maintenance above temperature > 25 ° C can cause oxidative stress due to heat stress in quail.
Perbandingan Respons Gastric Emptying Time dan Motilitas Usus Tikus (Rattus norvegicus) Muda dan Dewasa dengan Pemberian Jus Jeruk Utami, Dian Maulia; Pristihadi, Diah Nugrahani; Maheshwari, Hera; Hendry, Altaff; Andre, Daniel Latief; Rahman, Muhammad Luthfi; Permana, Nadine Hanifa; Yan, Teo Qin; Rudramurti, Win Satya
Buletin Anatomi dan Fisiologi Volume 10, Nomor 1, Tahun 2025
Publisher : Departemen Biologi Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/potensi.%Y.24444

Abstract

Umur hewan dan dosis obat diduga secara signifikan memengaruhi kinerja dan penyerapan sediaan oral. Penelitian ini bertujuan mengetahui perbandingan gastric emptying time (GET) dan respons motilitas usus tikus muda (berumur 3-4 minggu) dan dewasa (berumur 6-8 minggu). Penelitian menggunakan rancangan acak faktorial pada 12 ekor tikus muda dan 12 ekor tikus dewasa yang diberikan sediaan jus jeruk pada dosis 0-20 g/kg BB sebagai model obat yang bersifat asam. Selanjutnya, tikus dilakukan anestesi dan GET diukur. Motilitas usus diamati dengan pengukuran lintasan tinta cina yang ada di usus. Data yang diperoleh dianalisis menggunakan two-way ANOVA (p<0,05). Rata-rata GET fisiologis normal tikus muda setimbang dengan dewasa (59,00 dan 54,67 menit). Pemberian jus jeruk dengan dosis tertinggi (20 g/kg BB) memperpanjang GET secara signifikan. Ditemukan bahwa tikus yang berumur lebih dari 3 minggu memiliki panjang usus yang relatif konstan. Terhadap motilitas usus, peningkatan dosis pemberian jus jeruk dan umur tikus meningkatkan rasio marker dan kecepatan peristaltik secara signifkan. Kondisi ini menunjukkan bahwa peningkatan dosis jus jeruk memperpanjang GET dan motilitas usus, sementara penambahan umur hewan hanya meningkatkan motilitas usus tanpa memperpanjang GET. Oleh karena itu, dapat disimpulkan bahwa terdapat perbedaan respons pencernaan yang ditunjukkan oleh tikus berbeda umur terhadap obat asam.  Animal age and drug dose can significantly affect the performance and absorption of oral drugs. This study aimed to compare gastric emptying time (GET) and intestinal motility response in young (3-4 weeks old) and adult rats (6-8 weeks old). The study employed a factorial randomized design with 12 young and 12 adult rats, which were given 0-20 g/kg BW of orange juice as a model for acidic drugs. Afterward, the rats were anesthetized, and GET was measured. Intestinal motility was measured from the length of the Chinese ink trail in the intestine. Data were analyzed using two-way ANOVA (p<0.05). The results showed that GET in young rats was similar to that of adults (59.00 and 54.67 minutes). The highest dose of orange juice (20 g/kg BW) significantly prolonged GET. Rats older than three weeks showed relatively constant intestinal length. Regarding intestinal motility, both the dose of orange juice and age significantly increased the marker ratio and peristaltic speed. These findings suggest that higher doses of orange juice prolong GET and improve intestinal motility, while increasing age enhances motility without affecting GET. In conclusion, there were differences in digestive responses among rats of varying ages when exposed to acidic drugs.
Physiological and Productivity of Quail During The Egg-Laying Period with Supplementation of Senduduk (Melastoma Malabathricum L) Powder in Feed Fredi Kurniawan; Niken Ulupi; Hera Maheshwari
Acta VETERINARIA Indonesiana Vol. 13 No. 1 (2025): Maret 2025
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.13.1.44-51

Abstract

Quail is a type of poultry that is easy to raise and is the second largest egg producer after laying hens. The benefits of quail include a relatively high production cycle, minimal land requirements, and low feed consumption. Quail are more susceptible to stress compared to other poultry, particularly stress induced by elevated ambient temperatures. This stress can be overcome by administering antioxidants. Melastoma malabathricum L (commonly known as senduduk) leaf is a natural antioxidant that can alleviate stress. This study aimed to evaluate the effectiveness of different doses of senduduk leaf powder on the physiological and performance of laying quails. This study used a Completely Randomized Design with four treatments and four replications. The doses of senduduk leaf powder administered were P0 (0%), P1 (1.5%), P2 (3%), and P3 (4.5%). A total of 160 female quails, aged 40 weeks, were maintained for four weeks. The variables observed comprised hematological values, stress indicators, and quail performance during the laying period. The study’s results on hematological values, stress indicators, and quail performance during the laying period showed an increase at a dose of 3% (P2). The optimal concentration was identified as the 3% dose of senduduk leaf powder in treatment P2.
Method Modification of Developing Ischemic Stroke Animal Models Using Intravenous Catheters in Rats Perdhana, Ika Satya; Handharyani, Ekowati; Darusman, Huda Shalahuddin; Nugroho, Setyo Widi; Maheshwari, Hera; Fitri, Arni Diana
Acta VETERINARIA Indonesiana Vol. 13 No. 1 (2025): Maret 2025
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.13.1.67-76

Abstract

In various parts of the world, including Indonesia, the incidence of ischemic stroke remains high, and its impact poses a significant burden. This condition is influenced by numerous limitations in ischemic stroke therapy. Research on ischemic stroke is therefore crucial to develop, making the creation of appropriate animal models a vital necessity. One of the most commonly used methods by researchers to create animal models is the Middle Cerebral Artery Occlusion (MCAO) method. However, in Indonesia, its application remains limited due to the lack of available facilities. Method modifications can be implemented to enable the development of animal models in Indonesia. This study employed modifications to the MCAO method on eight Sprague Dawley rats. The modification involved using an intravenous catheter to facilitate the insertion of the filament as an occluder in the middle cerebral artery of the rats. Based on clinical and pathological observations, it can be concluded that the modified MCAO method used in this study is suitable for creating ischemic stroke animal models. With this modification, the creation of ischemic stroke animal models can be carried out in a simpler and more cost-effective manner.
Dynamics of intraerythrocytic parasite infections in the Java common palm civet (Paradoxurus hermaphroditus) Putri, Maritrana; Cahyaningsih, Umi; Ekastuti, Damiana Rita; Tarigan, Ronald; Achmadi, Pudji; Bustamam, Isdoni; Santoso, Koekoeh; Suprayogi, Agik; Maheshwari, Hera; Satyaningtijas, Aryani
ARSHI Veterinary Letters Vol. 8 No. 4 (2024): ARSHI Veterinary Letters - November 2024
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.8.4.93-94

Abstract

Selama tujuh minggu, penelitian ini menyelidiki infeksi parasit intraeritrosit pada musang Jawa (Paradoxurus hermaphroditus). Sampel darah dikumpulkan segera setelah musang dibawa dari habitat aslinya. Setelah periode adaptasi 30 hari, sampel tambahan dikumpulkan setiap minggu. Temuan kami mengungkapkan infeksi dengan Babesia sp., Theileria sp., dan Anaplasma sp., dengan tingkat infeksi tertinggi untuk Anaplasma sp. (0,35 ± 0,05)%, diikuti oleh Theileria sp. (0,12 ± 0,05)%, dan Babesia sp. (0,03 ± 0,02)%. Selama periode penelitian, tingkat infeksi Babesia sp. dan Anaplasma sp. menurun, sedangkan Theileria sp. menunjukkan tren peningkatan hingga akhir penelitian.
Physiological Performance and ‘Productivity of Quail’ Production Period with Addition Moringa Leaf Flour (Moringa oleifera L.) in Feed Nambut, Yohanes Baptisto; Niken Ulupi; Hera Maheshwari
Jurnal Ilmu Pertanian Indonesia Vol. 30 No. 4 (2025): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18343/jipi.30.4.644

Abstract

Moringa leaf powder is a processed product derived from the Moringa tree (Moringa oleifera L.). It contains a rich source of phytonutrients that are effective antioxidants that enhance the health status of humans and livestock. This study assesses quails' physiological performance and productivity during the production period when supplemented with Moringa leaf powder in their feed. The measured parameters include hematological values, stress indicators, performance, and egg chemical quality. The ‘study used 120 female’ quails aged 7 weeks, reared for 4 weeks. A Completely Randomized Design (CRD) was employed, consisting of four levels of dietary treatments and three replications. The supplementation of Moringa leaf flour was administered through feed for 28 days at each treatment level. ‘Data were analyzed using’ ANOVA (Analysis of Variance) and descriptive analysis. The results indicated that the addition of Moringa leaf flour in feed could maintain physiological performance, improve health status, reduce cholesterol levels in egg yolk, and increase iron (Fe) content in egg yolk. The best results in this study were obtained at a supplementation level of 7.5% Moringa leaf flour. The conclusion of this study is that Moringa leaf flour is feasible as a feed supplement at a dosage of up to 7.5%. Keywords: antioxidant, cholesterol level, egg yolk, feed supplement, stress indicator
Neurogical deficit score dan gambaran hematologi tikus model strok iskemik dengan metode middle cerebral artery occlusion Perdhana, Ika Satya; Hardiansyah, Muhamad Evans; Maheshwari, Hera; Mohamad, Kusdiantoro
ARSHI Veterinary Letters Vol. 9 No. 3 (2025): ARSHI Veterinary Letters - August 2025
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.9.3.83-84

Abstract

Stroke is a neurological disorder caused by impaired blood flow to specific regions of the brain, often resulting in paralysis and functional deficits in the affected area. Among its subtypes, ischemic stroke is the most prevalent in the general population. This study aimed to establish a rat model of ischemic stroke induced by middle cerebral artery occlusion (MCAO). Eight male Sprague-Dawley rats aged 8–10 weeks were randomly assigned to two groups: control and treatment group. In the treatment group, the middle cerebral artery was occluded for 45 min. Neurological assessment using the Bederson scale revealed a neurological deficit score (NDS) of 1, characterized by contralateral flexion after left-brain injury. Hematological analysis demonstrated significantly higher white blood cell (WBC) counts (p < 0.05), whereas red blood cell (RBC) counts, hemoglobin concentration, and hematocrit values were significantly lower (p < 0.05) than those in the control group. These findings indicate that the MCAO method with a 45-minute occlusion successfully induced a mild neurological deficit accompanied by distinct hematological alterations, thereby providing a reproducible animal model for ischemic stroke research.
Pemendekan waktu siklus estrus pada luwak Jawa (Paradoxurus hermaphroditus) terdeteksi melalui metode ulas vagina Zora, Nelda Fliza; Ulum, Mokhamad Fakhrul; Ekastuti, Damiana Rita; Tarigan, Ronald; Achmadi, Pudji; Bustaman, Isdoni; Santoso, Koekoeh; Maheshwari, Hera; Suprayogi, Agik; Manalu, Wasmen; Satyaningtijas, Aryani
ARSHI Veterinary Letters Vol. 7 No. 2 (2023): ARSHI Veterinary Letters - Mei 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.2.35-36

Abstract

Luwak Jawa (Paradoxurus hermaphroditus) merupakan salah satu hewan liar yang dapat dimanfaatkan sebagai penyeleksi biji kopi untuk menghasilkan kopi berkualitas dan bernilai ekonomis tinggi. Pemeliharaan yang tidak sesuai dapat memengaruhi kondisi fisiologis dan reproduksi luwak sehingga penting untuk diketahui sebagai dasar manajemen pemeliharaan dan kesehatan untuk optimalisasi produksi, pencegahan penyakit, dan konservasi luwak. Pemantauan ini bertujuan untuk mengetahui panjang waktu total siklus estrus dan waktu dari setiap fase estrus yaitu fase proestrus, estrus, metestrus dan diestrus. Luwak Jawa dari diperoleh dari pasar hewan sebanyak 2 ekor berjenis kelamin betina dengan bobot badan sekitar 4 kg diambil data ulas vagina selama 21 hari pada pagi dan sore hari. Sel epitel vagina diperiksa di bawah mikroskop dan dianalisa secara kuantitatif. Hasil pengamatan menunjukkan pemendekan siklus estrus dengan panjang total siklus estrus yaitu 121,5±7,5 jam (5 hari). Durasi waktu proestrus 12,0±0,0 jam, estrus 22,5±3,0 jam, metestrus 25,5±3,0 jam dan diestrus 61,5±3,0 jam.
Co-Authors . Herdis . Safrida . Yulnawati A. Suprayogi A. Wijaya A.S. Satyaningtijas ACHMAD FARAJALLAH Agik Suprayogi Agus Wijaya Ainul Khadija Saleema Akhiruddin Maddu Amelia Hana Amelia Ramadhani Anshar Anak Agung Gede Sugianthara Anak Agung Istri Sri Wiadnyani Andhika Yudha Prawira Andre, Daniel Latief Andriyanto Andriyanto Arief Boediono Asmarani Kusumawati Bambang Kiranadi Bambang Kiranadi Bambang Kiranadi Bambang Purwantara Claude Mona Airin D. R. Ekastuti Damhuri Damhuri Damiana Rita Ekastuti Danang Dwi Cahyadi David Anwar Dawanto, Jirfan Debby Jacqualine Jochebed Rayer Desrayni Hanadhita Desrayni Hanadhita Desrayni Hanadhita Diah Nugrahani Pristihadi Diani, Yusias Hikmat Dirwan Rahman Divo Jondriatno Divo Jondriatno Dondin Sajuthi Dwi Nurhidayah Zubaidah E Mulyati Effendi, E Mulyati Ekowati Handharyani Elok Budi Retnani ERIC HAYES Ernes Andhesfa Etih Sudarnika Eva Harlina Evi Juliati Evi Juliati Gani F. B. Harlimawan Faisal Tanjung Fitri, Arni Diana Fredi Kurniawan Gandasari, Ira Agustina Dewi Ganjar Maulana Nugraha Ganjar Maulana Nugraha Gilang Kala Maulana, Gilang Kala Hadi S Alikodra Hardiansyah, Muhamad Evans Hendry, Altaff heny Nitbani Herdis - Huda Salahuddin Darusman Huda Salahudin Darusman Huda Shalahudin Darusman Husna Husna, Mar’atul Husna, Rina Siti Nurul I wayan Teguh Wibawan ikhwan wirahadikesuma Ikhwan Wirahadikesuma Irfan Nurhidayat, Irfan Irwan Oktoni Isdoni Bustaman Jefri Naldi Julianto . Juliati Gani, Evi Juliati, Evi Jumadin, La Kasiyati Kasiati koekoeh santoso Kusdiantoro Mohamad Kusuma, Rini Anjarwati La Jumadin Lili Darlian Listya M.I, Mega LUTHFIRALDA SJAHFIRDI Luthfiralda Sjahfirji Luthfiralda Syahfirdi Maneewong, Sattabongkoch Mar’atul Husna Maria Fatima Palupi Maria Fatima Palupi Maria Fatima Palupi Maria Fatima Palupi Maria Prihtamala Omega Maryce Agusthinus Walukou Mega Listya M.I Meta Levi Kurnia Mirnawati Bachrum Sudarwanto Mokhamad Fakhrul Ulum, Mokhamad Mozes R. Tolihere MUHAMMAD ADIB MUSTOFA Muhammad Darjat Darulfalah Muhammad Darjat Darulfalah Muhammad Gunawan Muhammad Rizal Muhammad Zhaahir Mulyati Effendi MULYATI EFFENDI Nambut, Yohanes Baptisto Nastiti Kusomorini Nastiti Kusomorini Nastiti Kusumorini NASTITI KUSUMORINI NASTITI KUSUMORINI Niken Ulupi Nikki Aldi Nikki Aldi, Nikki Nugroho, Setyo Widi Nuri Ardiani Ong Huey, Lynette P. Achmadi Perdhana, Ika Satya Permana, Nadine Hanifa Pudji Achmadi Pudji Astuti PUDJI ASTUTI Pudji Astuti Pudji Astuti Pudji Astuti Purnomo, Rachmatullah Hadi Putri Indah Ningtias Putri Krida Gita P. Putri Krida Gita P. Putri, Fatimatus Sa’diyah Putri, Maritrana R. Tarigan Rachmatullah Hadi Purnomo Rahma Anisa Rahman, Muhammad Luthfi Reviany Widjajakusuma Reviany Widjajakusuma Reviany Widjajakusuma Ridi Arif Rina Siti Nurul Husna Risa Tiuria Rivany Widjajakusuma Rosdianto, Aziiz Mardanarian Rosdianto, Aziiz Mardanarian Rudramurti, Win Satya Safrida Safrida Sandra Hapsari Sandra Hapsari Santoso, Hera Sarmin - Sasmita, Annissa Nuridfi Satvika, Fadhila Siagian, Forman Erwin Slamet Widiyanto Srihadi Agungpriyono Sumiaty Aiba Supratikno . Tarigan, Ronald Teguh Budipitojo Trini Suryowati, Trini Tuty Laswardi Yusuf Umi Cahyaningsih Utami, Dian Maulia W. Manalu Wasmen Manalu Wisnugroho Agung Pribadi Wisnugroho Agung Pribadi Yan, Teo Qin YENI KEZIA BEKALANI Yulnawati - Yulvian Sani Yusfiati Yusfiati Zora, Nelda Fliza