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All Journal AKSIOMA: Jurnal Program Studi Pendidikan Matematika Jurnal Penelitian Pendidikan Matematika Jurnal Pendidikan Matematika JCES (Journal of Character Education Society) AMPIBI: Jurnal Alumni Pendidikan Biologi  Jurnal Kartika Kimia JAGAT (Jurnal Geografi Aplikasi dan Teknologi) Jurnal Amal Pendidikan Jurnal Manajemen, Bisnis dan Organisasi (JUMBO) Amal Ilmiah: Jurnal Pengabdian Kepada Masyarakat GEMBIRA (Pengabdian Kepada Masyarakat) Jurnal Pengabdian Masyarakat Jurnal Pengabdian dan Pemberdayaan Kesehatan Aksi Kita: Jurnal Pengabdian Kepada Masyarakat Indonesia Berdampak: Jurnal Pengabdian Kepada Masyarakat
Hasnawati Hasnawati
Universitas Halu Oleo
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Cytotoxic Activity of Chromolaena odorata Ethyl Acetate Fraction and Its Inhibitory Mechanism Through Cell Cycle Modulation Against WiDr Colon Cancer Cells Asniar Pascayantri; Hasnawati Hasnawati; Dian Munasari Solo; Nurramadhani A. Sida; Wa Ode Nurhayati Basri; Sarida Sarida; Aisyah Aisyah; Nurul Azizah Putri Herina; Muhammad Bagas Rahya Arafat
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1057

Abstract

Chromolaena odorata has traditionally been used to treat various diseases such as bacterial and fungal infections, external wounds, stomach ulcers, and vomiting blood. Its anticancer activity has been extensively studied. This study aims to prove the cytotoxic effect of Chromolaena odorata leaves on WiDr colon cancer cells and its inhibitory mechanism through cell cycle modulation. Dried Chromolaena odorata leaves were extracted by maceration using 96% ethanol. They were then triturated with n-hexane and ethyl acetate to obtain n-hexane and ethyl acetate fractions. The ethyl acetate fraction was then screened for phytochemicals using the tube method and tested for cytotoxicity using the MTT assay. The selectivity index (SI) was calculated by comparing the IC50 of WiDr cells to Vero cells. Cell cycle modulation was then observed using flow cytometry. The results showed that the ethyl acetate fraction of Chromolaena odorata leaves contained flavonoids, phenolics, and tannins, and was moderately cytotoxic to WiDr cells with an IC50 of 207.69 µg/mL,, with an SI of 3.5. The ethyl acetate fraction of Chromolaena odorata was able to inhibit the growth of WiDr colon cancer cell division through the G2/M and Sub G1 phases. Thus, it was concluded that the ethyl acetate fraction of Chromolaena odorata has great potential to be developed as a candidate source of colon anticancer agents.
Analysis of Phenolic, Flavonoid Content, and Antioxidant Activity of Combination of Pumpkin Leaves (Cucurbita moschata Durch.) and Aibika Leaves (Abelmoschus manihot L.) Fractions Ari Sartinah; Yamin Yamin; Hasnawati Hasnawati; Suryani Suryani; Nur Illiyyin Akib; Hikmawati Supu
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1058

Abstract

This study aims to determine the total phenolic and flavonoid content of ethyl acetate fractions from pumpkin (Cucurbita moschata Durch.) and aibika (Abelmoschus manihot L.) leaves, and to evaluate the antioxidant activity of their combined fractions. Analysis of total phenolics and flavonoids content was carried out using UV-Vis spectrophotometry with gallic acid (phenolics) and quercetin (flavonoids) as standards. Antioxidant potential testing was carried out using the DPPH method. The results showed that the phenolics content of the ethyl acetate fraction of PLand ALwas 60.81 and 56.47 mgEAG/g, respectively, while the total flavonoids content of the ethyl acetate fraction of PLand ALwas 64.54 and 55.07 mgEK/g, respectively. The IC50 value of the combination of ethyl acetate fractions of PLand ALwith a ratio of 3:2 was 4.686 μg/mL, while the single ethyl acetate fractions of PLand ALwere 7.040 and 7.549 μg/mL, respectively. This indicates that increasing antioxidant activity can be done by combining fractions from two or more types of plants.
PENINGKATAN KESADARAN MASYARAKAT TENTANG JAMU KEBUGARAN YANG AMAN DAN TERSTANDARISASI SEBAGAI LANGKAH PENCEGAHAN PENYALAHGUNAAN OBAT TRADISIONAL DI KELURAHAN KAMBU Dian Munasari Solo; Asriullah Jabbar; Hasnawati Hasnawati; Fadhliyah Malik; La Ode Muhammad Fitrawan; Nasrudin Nasrudin; Rahmat Muliadi; Elvi Rahmayani; Nurlian Nurlian; Asrumin Asrumin; Asniar Pascayantri; Vica Aspadiah; Mubarak Mubarak; Muhammad Ilyas Y.
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 6 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i6.2618

Abstract

Obat tradisional (Jamu) tetap populer di Indonesia karena dianggap aman dan terjangkau. Namun, informasi yang keliru sering kali menyebabkan penggunaan yang tidak tepat serta kurangnya pemahaman mengenai manfaat kesehatan jangka panjang dan standar ilmiah yang berlaku. Di Kelurahan Kambu, pengetahuan masyarakat tentang pemanfaatan jamu yang aman dan terstandarisasi masih sangat terbatas. Program ini bertujuan untuk meningkatkan literasi kesehatan masyarakat dalam upaya pencegahan penyalahgunaan jamu, sekaligus mendorong perilaku konsumsi herbal yang aman dan rasional sesuai dengan standar regulasi yang berlaku. Kegiatan pengabdian kepada masyarakat ini dilaksanakan di Kelurahan Kambu, Kendari, dengan menggunakan pendekatan kunjungan dari rumah ke rumah. Intervensi yang diberikan meliputi ceramah interaktif, diskusi, serta pembagian leaflet informatif kepada 14 responden. Materi edukasi mencakup identifikasi jamu, teknik produksi yang terstandarisasi (CPOTB), serta protokol "CEK KLIK" (Cek Kemasan, Label, Izin edar, dan Kedaluwarsa). Program ini berhasil meningkatkan pemahaman dan keterampilan masyarakat dalam mengolah bahan herbal seperti kunyit, jahe, madu, dan meniran menjadi minuman kebugaran yang aman. Para peserta memperoleh wawasan mengenai takaran, standar keamanan, serta cara memverifikasi registrasi produk melalui kanal resmi BPOM. Integrasi kearifan lokal dengan pendekatan ilmiah terbukti efektif dalam memperkuat kesadaran masyarakat terhadap penggunaan obat tradisional yang aman dan rasional.
SOSIALISASI PERAN APOTEKER DALAM MENCEGAH PENGGUNAAN KOSMETIK ILEGAL PADA SISWA/SISWI KELAS XI SMKS TUNAS HUSADA KENDARI Hasnawati Hasnawati; Rifa’atul Mahmudah; Nur Azizah; Zabrina D. Masjidi; Umi Hasana; Crisna Welliam; Kharisma Restu Al Hijrah Ode
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 6 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i6.2708

Abstract

The use of cosmetics among adolescents is increasing due to beauty trends and easy access to cosmetic products. However, low awareness in identifying safe and legal cosmetics raises the risk of exposure to products that do not comply with safety standards. This community service program aimed to improve the knowledge and awareness of students at SMK Tunas Husada Kendari regarding the identification and selection of safe and legal cosmetics through interactive education. The activities included counseling sessions, group discussions, Q&A, and evaluation using pre-test and post-test questionnaires. The results showed a significant increase in students’ understanding after the intervention. Participants were able to recognize the characteristics of safe cosmetics, verify product legality using BPOM registration numbers via the BPOM Mobile application, and understand the health risks of illegal cosmetics such as mercury, hydroquinone, and steroids. In conclusion, interactive educational methods proved effective in enhancing students’ knowledge and encouraging them to become smart consumers who prioritize skin health and product safety.
PENINGKATAN PENGETAHUAN SISWA SMP NEGERI 10 KENDARI TENTANG PENGELOLAAN OBAT MELAUI EDUKASI DAGUSIBU Parawansah Parawansah; Hasnawati Hasnawati; Aulia Sakinah Diah; Indah Latif; Nidya Aftira; Suchi Febriani; Yuliani Uzuni
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 7 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Juli 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i7.2718

Abstract

DAGUSIBU merupakan program edukasi yang memberikan panduan mengenai cara pengelolaan obat yang benar. Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan siswa SMP Negeri 10 Kendari tentang pengelolaan obat yang benar. Metode yang digunakan berupa penyuluhan melalui ceramah, media presentasi, leaflet, diskusi, dan tanya jawab kepada 30 siswa anggota OSIS. Kegiatan diawali dengan pretest untuk mengetahui pengetahuan awal peserta, kemudian dilanjutkan dengan penyampaian materi dan evaluasi melalui sesi tanya jawab. Hasil menunjukkan adanya peningkatan pemahaman yang ditandai oleh antusiasme, keaktifan dalam diskusi, serta kemampuan siswa menjawab pertanyaan  dengan  benar.  Edukasi  DAGUSIBU  efektif  meningkatkan pengetahuan siswa mengenai penggunaan obat yang rasional dan diharapkan mendorong perilaku pengelolaan obat yang benar dalam kehidupan sehari-hari.
Edukasi Anemia sebagai Masalah Kesehatan Masyarakat: Determinan, Dampak, dan Strategi Penanggulangannya Ruslin Ruslin; Nasrudin Nasrudin; Irnawati Irnawati; Hasnawati Hasnawati; Wahyuni Wahyuni; Sahidin Sahidin; Ari Sartinah; Suryani Suryani; Loly Subhiaty Idrus; Rahmat Muliadi; Abdi Nipangeran; Agustina Agustina; Siti Rahmawati Ondjo
Jurnal Pengabdian dan Pemberdayaan Kesehatan Vol. 3 No. 2 (2026): Juni 2026
Publisher : Menara Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70109/jupenkes.v3i2.115

Abstract

Anemia merupakan masalah kesehatan masyarakat yang signifikan, khususnya pada kelompok perempuan usia subur dan remaja putri. Kegiatan pengabdian kepada masyarakat ini bertujuan memberikan edukasi tentang penyebab, dampak, pencegahan, dan penanganan anemia kepada masyarakat Desa Waworaha, Kecamatan Soropia, Kabupaten Konawe, Sulawesi Tenggara. Kegiatan dilaksanakan pada tanggal 18 April 2026 di Balai Desa Waworaha dengan melibatkan 17 peserta. Metode yang digunakan berupa penyuluhan interaktif menggunakan media flyer, brosur, dan presentasi lisan, dilanjutkan dengan sesi diskusi tanya jawab. Pemeriksaan tekanan darah dan kadar hemoglobin (Hb) juga dilakukan sebagai bagian dari skrining kesehatan. Hasil kegiatan menunjukkan bahwa dari 17 peserta, 5 orang (29,4%) teridentifikasi mengalami hipertensi dan 1 orang (5,9%) mengalami anemia. Mayoritas peserta adalah perempuan (82,4%) dengan rentang usia 20 hingga lebih dari 60 tahun. Kegiatan berlangsung selama satu jam dan dinilai berhasil meningkatkan pemahaman masyarakat tentang anemia serta langkah-langkah pencegahannya.
EDUKASI PENCEGAHAN PENYALAHGUNAAN NAPZA BAGI SISWA SMAN 4 KONAWE SELATAN Wa Ode Sitti Zubaydah; Nur Illiyyin Akib; Hasnawati Hasnawati; Lade Aburifal Basri; Amina Amina; Ana Aprilia Azzahrah; Annisa Rizki; Annisa Purnama Sari; Andini Risky Khaerunnisa Silondae; Andi Rafita Ayu Risky Utami; Suci Wahyuni
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Januari 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i1.2260

Abstract

Drug abuse involving Narcotics, Psychotropics, and Other Addictive Substances (NAPZA) poses a serious threat to the physical and mental health as well as the future of young generations. Adolescents, as a vulnerable group, require systematic and sustainable educational interventions to enhance their knowledge and awareness of the risks and consequences of drug abuse. This community service activity aimed to improve students’ understanding of the types, risk factors, and impacts of NAPZA abuse through participatory health education. The implementation method consisted of preparation, inter-institutional collaboration, human resource readiness, and educational activities including pretest, material delivery through lectures and discussions, brief consultations, and posttest evaluation. The activity involved 35 students of SMAN 4 Konawe Selatan and was conducted by students of the Pharmacist Professional Education Program, Universitas Halu Oleo, in collaboration with the South Konawe District Health Office. The evaluation results demonstrated a significant improvement in students’ knowledge levels, with the proportion of students in the good knowledge category increasing from 42.86% before the intervention to 71.43% after the intervention, while the poor knowledge category decreased to 8.57%. These findings indicate that health education on NAPZA is effective in enhancing students’ knowledge and awareness of the dangers of drug abuse. This program is expected to serve as a sustainable collaboration model between educational institutions and health authorities in promoting preventive efforts against drug abuse among adolescents.
STAY NATURAL, STAY SAFE: GERAKAN CERDAS MENINGKATKAN KESADARAN MASYARAKAT KELURAHAN ANAWAI TERHADAP PENGGUNAAN OBAT TRADISIONAL YANG TEPAT DAN AMAN MELALUI EDUKASI BERBASIS LITERASI KESEHATAN Asniar Pascayantri; Hasnawati Hasnawati; Irnawati Irnawati; Dian Munasari; Agus Silfia Susanto; Nasrudin Nasrudin; Indah Nurcahaya Sari; Laila Qodriyah Karimu; Mayang Sari; Nurfadillah Sudia; Padil Anugrah; Afifah Nur Ramadhani; Angelina Lisar; Muhammad Ilyas Y; Mubarak Mubarak; Chetrin Priliyani; Asriullah Jabbar
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Januari 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i1.2277

Abstract

The widespread use of traditional medicine in Indonesian communities is often not accompanied by adequate awareness of safety, legality, and rational use. This community service program, entitled “Stay Natural, Stay Safe”, aimed to enhance public awareness of proper and safe traditional medicine use through health literacy–based education in Anawai Village, Kendari City. The intervention employed a door-to-door pharmaceutical communication approach supported by printed educational leaflets as communication, information, and education (CIE) media. Activities were conducted through observation, educational counseling, practical demonstrations, and evaluation. The evaluation results showed a high level of community understanding, with a mean score of 4.49 and an achievement rate of 89.73%, categorized as very good. These findings indicate that health literacy–based education supported by leaflets effectively improves community awareness, confidence, and rational behavior in traditional medicine use and can serve as a sustainable community-based health promotion strategy.
EDUKASI KESEHATAN REMAJA MELALUI KAMPANYE PENCEGAHAN MEROKOK, VAPE, MINUMAN KERAS, DAN PERGAULAN BERESIKO PADA SISWA SMA NEGERI 1 SAWA Hasnawati Hasnawati; Muhammad Arba; La Ode Muhammad Fitrawan; Astrid Indalifiany; Loly Subhiaty Idrus; Asniar Pascayantri; Nurramadhani A. Sida; Dian Munasari Solo; Fadhliah Malik; Irvan Irvan; Ari Sartinah; Ocha Olyvia; Aisah Fitriani Aksan
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 4 (2026): BESIRU : Jurnal Pengabdian Masyarakat, April 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i4.2514

Abstract

Adolescence is a vulnerable period for risky behaviors such as smoking, vaping, alcohol consumption, and unsafe social relationships. Limited health literacy often causes adolescents to perceive these behaviors as normal. This community service program aimed to improve the knowledge and awareness of students at SMA Negeri 1 Sawa regarding the dangers of smoking, vaping, alcohol consumption, and the risks of unsafe social behavior and HIV/AIDS. The activity was conducted on January 2026, at SMA Negeri 1 Sawa, Konawe Utara Regency, involving 40 twelfth-grade students. The methods used included interactive counseling, discussion, question-and-answer sessions, educational games, and simple demonstrations. The results showed an increase in students’ understanding of the dangers of smoking and vaping, the negative effects of alcohol consumption, and the risks associated with unsafe social behavior. Students began to understand that vaping is not a safe alternative to smoking and that risky behaviors may affect their reproductive health and future. The high level of student participation during the discussion indicated that an interactive approach is effective for adolescent health education.
Pelatihan Pembuatan Makanan Telur Dadar Lumpia pada Masyarakat Tobimeita Kecamatan Nambo Rizal Rizal; Abdullah Igo BD; Muh. Ilham; Hasnawati Hasnawati; Murni Nia; Nurvianti Nurvianti; Harjun Harjun
Aksi Kita: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 3 (2026): MEI-JUNI
Publisher : Indo Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63822/ym5w3d78

Abstract

Pelatihan ini dilaksanakan untuk pemberdayaan masyarakat dalam penyusunan Rencana Pengabdian Kepada Masyarakat (PKM) bagi masyarakat tobimeita kecamatan Nambo. Metode yang digunakan dalam kegiatan ini adalah pemberian materi, praktek secara langsung dan pendampingan. Pemberian materi dilakukan di rumah salah satu warga yang ada di kelurahan tobimeita, dengan materi tentang ekonomi kreatif serta pemberian pelatihan secara langsung untuk mengenalkan berbagai pilihan alternative untuk dapat berkreatifitas serta berwirausaha muda dengan bahan yang mudah ditemukan dilingkungan sekitar kepada masyarakat tobimeita kecamatan Nambo. Teknik pembuatan makanan dari telur dadar lumpia dengan pendampingan serta praktek pembuatan makanan telur dadar lumpia
Co-Authors ,, Suryani Abdi Nipangeran Abdullah Igo BD Abdullah Igo, BD Afifah Nur Ramadhani Agus Silfia Susanto Agustina Agustina Ahdiat Agriansyah Ahmad Hidayat Aisah Fitriani Aksan Aisyah Aisyah Amina Amina Ana Aprilia Azzahrah Andi Rafita Ayu Risky Utami Andini Risky Khaerunnisa Silondae Angelina Lisar Annisa Purnama Sari Annisa Rizki Arba, Muhammad Ari Sartinah Arvyaty Arvyaty Asniar Pascayantri Aspadiah, Vica Asriullah Jabbar Asrumin Asrumin Astrid Indalifiany Aulia Sakinah Diah Awaludin Awaludin Busnawir Busnawir Chetrin Priliyani Crisna Welliam Damhuri Damhuri Dian Munasari Dian Munasari Solo Elvi Rahmayani Endri Nuryanto Endro Sukotjo Fadhliah Malik Fadhliyah Malik Fitrawan, La Ode Muhammad Fristiohady, Adryan Ghais S. Daud Hafiludin Samparadja Harjun, Harjun Hendrik Hendrik Hikmawati Supu Ida Ayu Putri Andini Indah Latif Indah Nurcahaya Sari Intan Permata Putri Iradat Salihin Irnawati Irnawati Irvan Irvan Isalman, Isalman Jafar Jafar Kasmawati, Henny Kharisma Restu Al Hijrah Ode Kodirun La Masi La Ndia, La Ndia La Ode Muhammad Yamin Lade Aburifal Basri Laila Qodriyah Karimu Lambertus Lambertus Leni Melani Lili Darlian Loly Subhiaty Idrus M. Sirih Mayang Sari Misu, La Mohamad Salam Mubarak Mubarak Muh. Ilham Muh. Ilyas Y Muhammad Bagas Rahya Arafat Muhammad Ilyas Y Muhammad Ilyas Y Muliddin Murni Nia Mustamin Anggo Nasrudin Nasrudin Nidya Aftira Noer Juniaty Noor Husna Khairisa Nur Azizah Nur Illiyyin Akib Nur Illyin Nurfadillah Sudia Nurhikmawati Nurhikmawati Nurlian Nurlian Nurramadhani A. Sida Nurul Azizah Putri Herina Nurvianti Nurvianti Ocha Olyvia Padil Anugrah Parawansah Parawansah Rahmad Prajono Rahmat Mualiadi RAHMAT MULIADI, RAHMAT Rezkiati Rezkiati Rifa’atul Mahmudah Rizal Rizal Ruslin Ruslin Sabarudin Sabarudin Safilu Safilu Sahidin Sahidin Saleh Saleh Salim Salim Sarida Sarida Siti Rahmawati Ondjo Siti Risnawati Sitti Nur Astuti S. Sri Risky Manurani Suchi Febriani Suci Wahyuni Suhar Suhar Tissa Filiany Mangari Umi Hasana Wa Ode Indrawati Wa Ode Nurhayati Basri Wa Ode Sitti Zubaydah Wahyuni Wahyuni Yamin Yamin Yuliani Uzuni Yusuf Yusuf Zabrina D. Masjidi Zamsir Zamsir Zulfaidil Zulfaidil