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All Journal Journal of Food and Pharmaceutical Science JURNAL ILMIAH KESEHATAN KEPERAWATAN Disease Prevention and Public Health Journal Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology Pharmacon Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Pharmascience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Sains dan Komunitas Jurnal Surya Medika Majalah Farmaseutik Indonesian Journal of Chemistry PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal Mandala Pharmacon Indonesia BALABA (JURNAL LITBANG PENGENDALIAN PENYAKIT BERSUMBER BINATANG BANJARNEGARA) Jurnal Ilmiah Pharmacy PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Journal of Food and Pharmaceutical Sciences Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Indonesian Journal of Pharmacology and Therapy

Laela Hayu Nurani

Universitas Ahmad Dahlan

Author-ID : 334257

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Formulasi dan Uji Anti Inflamasi Masker Peel Off Ekstrak Etanol Buah Mengkudu (Morinda citrifolia L.) Miratun Syarifah; Nining Sugihartini; Laela Hayu Nurani
JURNAL ILMU KEFARMASIAN INDONESIA Vol 17 No 2 (2019): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Infl ammation of the skin often occurs in acne-prone skin. Acne can be prevented in variousways, one of them by maintaining clean skin. Noni fruit (Morinda citrifolia L.) with the active ingredientof scopoletin has been proven to be eff ective as an anti-infl ammatory. Noni is dried into simplicia,extracted was ethanol 96% solvent until it becomes concentrated extract. The extract is formulated intoa peel off mask with a concentration variation of 5%, 10 and 15%. The masks produced is evaluated forphysical characteristic of pH, viscosity, spreadability, and adhesivity test), as well as anti-infl ammatoryproperties using mice with the parameters of COX-2 expression and irritation test using rabbit. Theevaluation results of the physical characteristic of the peel off mask fulfi lled the physical characteristicrequirements of the peel off mask preparation. Whereas in the viscosity test there were groups thatmet the viscosity requirements, namely the formula I and II groups and the group that did not meet theviscosity requirements, namely the formula III group. Anti-infl ammatory test in mice showed that themask lead to reduction in the amount of COX-2 expression. The best formula in 3 preparations wasindicated in formula I with COX-2 expression value of 22.635%. The results of irritation test on rabbitsdid not cause irritation. According to the test results it can be concluded that the optimum value of theethanol extract concentration is shown in formula I with a concentration of 5%.

In Vitro Antiplasmodial Activity and Cytotoxicity of Isolates of Pasak Bumi (Eurycoma longifolia Jack) Root Eti Nurwening Sholikhah; Mahardika Agus Wijayanti; Laela Hayu Nurani; Mustofa Mustofa
Majalah Farmaseutik Vol 14, No 2 (2018)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Previous study showed that methanol soluble fractions of Eurycoma longifolia Jack showed a high in vitro antiplasmodial activity, however there is no explanation which isolate is active as antiplasmodial. This study was conducted to evaluate the in vitro antiplasmodial activity and cytotoxicity of 5 isolates of E. longifolia root isolated from methanol soluble fractions. The in vitro antiplasmodial activity was tested on two strains of P. falciparum, FCR-3 and D10 while their cytotoxicity was tested on normal Vero cell line. The antiplasmodial activity and the cytotoxicity were presented as the Inhibitory Concentration 50% (IC50) which showed the concentration of isolate which inhibit the Plasmodium or Vero cell line growth 50%. The IC50 value was determined by probit analysis. The selectivity of isolate was determined by calculating the ratio of the cytotoxicity (IC50 on Vero cell line) with the antiplasmodial activity (IC50 on Plasmodium). The results showed that isolate 4 and 5 showed high antiplasmodial activity with IC50 value 2.21-19.02, 13.54-64.73 µg/mL respectively. The cytotoxic/antiplasmodial ratio indicates that isolate 4 and 5 have also high selectivity with value 11.74-68.75 for isolate 4, and 66.01-316.51 for isolate 5. For conclusion, the isolate 4 and 4 showed the high aniplasmodial activity with the high selectivity

The effect of co-chemotherapy of ethyl acetate fraction of Long jack roots (Eurycoma longifolia jack) on interleukin-6 expression of 7,12- dimethylbenz anthrasen breast carcinoma model Siti Salma Yusuf; Laela Hayu Nurani; Sitarina Widyarini
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art7

Background: Carcinogenic compound can cause cancer, one of which is 7,12- Dimethylbenz anthrasen (DMBA). Therapy used is chemotherapy using doxorubicin. However, doxorubicin can cause side effects and not specific enough, so it can also impair normal cells and cause resistance, so Long jack roots are needed as co- chemotherapy agent.Objective: To assess the effect of giving co-chemotherapy ethyl acetate fraction of Long jack roots and doxorubicin on the development of breast cancer through inhibition interleukin-6 expression.Methods: A total of 35 female rats SD strain were divided into 5 intervention group, each group contained 7 rats, namely Group 1 (baseline given feed and water), Group 2 (DMBA 20 mg / kg given 2x a week for 5 weeks), Group 3 (DMBA 20mg / kg + Long jack roots Ethyl acetate fraction 100 mg / kg), Group 4 (DMBA 20 mg / kg + Doxorubicin 1,17mg / kg), Group 5 (DMBA 20 mg / kg + Long jack roots ethyl acetate fraction 100 mg / kg + Doxorubicin 1,17mg / kg), then on the 16th week, surgery was done to remove animal’s mammae and organs and to conduct immunohistochemistry test with anti interleukin-6. Results: Interleukin-6 expression test result% with the average value of group I, II, III, IV and V respectively, 6.56 ± 3.50%; 47.21 ± 9.48%; 20.83 ± 10.40%; 49.39 ± 9.87% and 58.37 ± 17.32%.Conclusion: The administration of co-chemotherapy ethyl acetate fraction of longjack roots (Eurycoma longifolia Jack) and doxorubicin is effective inlowering aromatase expression, however not effective in reducing IL-6 expression compared to single regiment doxorubicin in DMBA-induced rat models.

Effects of co-chemotherapy ethyl acetate fraction of eurycoma longifolia jack roots and doxorubicin against apoptosis through expression p53 mutant and Bcl-2 Galih Dwi Mulyati; Laela Hayu Nurani; Sitarina Widyarini
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 8, No 1, (2017)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol8.Iss1.art9

Background : It was found mutations of p53 gene in Breast cancer. Mutant p53 protein caused a decrease in cell apoptosis mechanisms through increased expression of Bcl-2. Breast cancer therapy is commonly used chemotherapy using Doxorubicin. However, effectiveness of the use of this chemotherapeutic agent is limited due to the emergence of side effects and toxic to normal cells. Therefore, it is necessary to develop new drugs for combination of chemotherapy. Eurycoma longifolia Jack roots has the potential as co-chemotherapy of breast cancer and it is not toxic to normal cells. Method : Rats were divided into 5 groups. Each group consisted of four female white Sprague Dawley rats. Group 1 (Normal), group 2 (DMBA 20 mg/kgB.W), group 3 (DMBA +Doxorubicin 1.12 mg/kgB.W), group 4 (DMBA +fractions 100 mg/kgB.W), group 5 (DMBA+Doxorubicin +fractions). All the rats were sacrificed at weeks 16 and to be taken their breast tissue. Immunohistochemistry was performed using a mouse monoclonal antibody mutant (BioGenex) and Bcl-2 (BIOSS). Results : expression of mutant p53 percentage obtained for group I (9.35 ± 0.32)%, II (21.65 ± 1.60)%, III (10.72 ± 2.52)%, IV (11.63 ± 3.39)%, V (12.72 ± 3.44)%, While the percentage of Bcl-2 expression obtained for I (20.62 ± 10.09)%, II (52.83 ± 3.61)%, III (24.38 ± 3.54)%, IV (38.01 ± 6.25)%, V (27.99 ± 4.27)%. The data was statistically tested by Kruskal Wallis test (p< 0.005). Conclussion : Co-chemotherapy of E. longifolia Jack roots and Doxorubicin can stimulate apoptosis through decreased in the expression of mutant p53 protein and Bcl-2 in breast tissue of rats induced by DMBA.

Authentication of Lemongrass Oil By Gas Chromatography-Mass Spectroscopy (GC-MS) Combination Chemometrics Any Guntarti; Husnun Khairunnisa Pratiwi; Laela Hayu Nurani; Ibnu Gholib Gandjar
Indonesian Journal of Pharmaceutical Science and Technology Vol 9, No. 3, 2022
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v9i3.32558

The addition of something foreign to lemongrass essential oil has been done since ancient times. One way is to add turpentine oil which aims to increase the volume and grade of the smell. The purpose of this study was to determine the authentication of citronella oil using the gas chromatography-mass spectrometry (GC-MS) method combined with multivariate PCA analysis. Fragrant lemongrass oil was isolated by distillation of water and using simplicia in the form of powdered dried Cymbpogon citratus leaves. The oil obtained was treated with anhydrous Na2SO4. The results of the characteristics and quality requirements of citronella oil are compared with the SNI. The results of GC-MS analysis were the relative levels of essential oils. The results of the characteristic test meet the quality requirements of SNI 06-3953-1995, except for the yield requirements. The results of analysis by GC-MS, the essential content of citronella oil was citronella (37.47%), geraniol (25.03%), trans-caryophilene (3.69%), citronellol (11.68%), and delta cadinene. (2.44%). Chemometric principle component analysis (PCA) can group samples of fragrant lemongrass oil, turpentine oil and lemongrass oil products on the market.

ANALISIS PROFIL MINYAK DAUN CENGKEH (Syzygium aromaticum (L.) Merr. & L. M. Perry) DAN PRODUK DI PASARAN : PROFILE ANALYSIS OF CLOVE LEAF OIL (Syzygium aromaticum (L.) Merr. & L. M. Perry) AND PRODUCTS IN THE MARKET Any Guntarti; Putri Lestari; Laela Hayu Nurani
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.534

Minyak cengkeh memiliki nilai komersial dan manfaat yang besar serta permintaan ketersediaan minyak cengkeh di pasaran sangat tinggi, namun hasil ekstraksi minyak cengkeh cukup rendah sekitar 2-3% sehingga dapat menimbulkan motif untuk mengeksplorasi pasokan minyak daun cengkeh dengan tindakan pemalsuan. Tujuan dari penelitian ini untuk menganalisis secara kualitatif profil dan kemurnian minyak daun cengkeh dan produk minyak daun cengkeh di pasaran berdasarkan persyaratan mutu dari Standar Nasional Indonesia (SNI). Jenis penelitian ini berupa penelitian non eksperimental. Minyak daun cengkeh dan minyak produk A, B dan C dilakukan uji kualitas minyak berdasarkan syarat uji SNI 06-2387-2006 yang meliputi organoleptis (warna dan bau), bobot jenis, indeks bias dan kelarutan dalam etanol 70%. Selanjutnya dilakukan analisis KLT dengan menggunakan fase diam silika gel GF254 dan fase gerak Toluen : Etil Asetat (93:7). Hasil destilasi minyak daun cengkeh sebanyak 3 Kg dengan destilasi uap air didapatkan rendemen sebesar 0,83%. Hasil analisis profil minyak menunjukkan bahwa minyak daun cengkeh dan minyak produk A memenuhi syarat uji SNI 06-2387-2006, sedangkan pada minyak produk B dan C terdapat beberapa parameter pengujian yang tidak memenuhi syarat uji di antaranya bobot jenis, indeks bias dan kelarutan dalam etanol 70%, sedangkan pada hasil uji dengan KLT menunjukkan pola noda yang sama dengan nilai Rf sebesar 0,63.

Chemometrics-Assisted UV-Vis Spectrophotometry for Quality Control of Pharmaceuticals: A Review Laela Hayu Nurani; Citra Ariani Edityaningrum; Irnawati Irnawati; Anggita Rosiana Putri; Anjar Windarsih; Any Guntarti; Abdul Rohman
Indonesian Journal of Chemistry Vol 23, No 2 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.74329

Spectroscopic method in the UV-Vis region is considered the most molecular spectrometric method for content determination of a single component. However, a lot of pharmaceutical dosage forms comprise two or more components which lead to peak overlapping. Moreover, in the chemical stability test, active pharmaceutical ingredient (API) was also found along with the degradation products, impurities, and adulterant compounds. UV-Vis spectroscopy is one of the methods of choice for the determination or quantification of a single component in pharmaceutical preparations. The pharmaceutical products typically contain two or more APIs having chromophoric agents capable of absorbing UV-Vis beams and the absorbance values are summative from the absorption of each UV-Vis active compound according to the additive nature of Lambert-Beer law. The main problem for the simultaneous determination of API along with impurities and the degradation products in pharmaceutical preparations is the presence of overlapping peaks of UV-Vis spectra. The chemometrics-assisted spectroscopy is one of the analytical efforts to solve these problems. This review highlighted the application of chemometrics in combination with UV-Vis spectroscopy for the assay of API, impurities, adulteration issues and degradation products present in pharmaceutical dosage forms.

QUALITY ANALYSIS AND IDENTIFICATION OF FUNCTIONAL GROUPS OF SWEET ORANGE (Citrus sinensis) PEEL ESSENTIAL OIL USING FTIR Citra Dhea Cantika; Laela Hayu Nurani; Nina Salamah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 4 (2023): Forthcoming Issue
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i4.898

Organic waste in the form of citrus fruit peels has not been handled seriously, causing environmental pollution, such as the emergence of unpleasant odors. Therefore, waste management becomes a more valuable product or item. Citrus peel oil counterfeiting often occurs because there is no Indonesian National Standard (SNI) for citrus peel oil as a quality standard, making it difficult to identify the falsity of finished citrus peel oil products in the market. Research was conducted to test the quality of sweet orange peel oil so that it could be used as a standard to identify the content of sweet orange peel oil using the FTIR method. Oil quality testing included an organoleptic test, specific gravity, refractive index, and acid number. The oil quality test results showed clear yellow oil with a distinctive sweet orange peel aroma, specific gravity of 0.845, refractive index of 9.263, and acid number of 1.1. FTIR analysis revealed spectra that appeared in the region of 1490 with strong intensity (C-H aromatic), 1645 with medium intensity (C=C), and 2860 with medium intensity (C-H aliphatic). FTIR spectra of sweet orange peel oil showed similarity with limonene with a hit quality value of 958, the content of sweet orange peel oil is dominated by limonene compounds. Keywords: sweet orange peel, Essential oil, FTIR, Limonene, Oil quality

Analysis of soft gelatin capsule with real-time polymerase chain reaction for halal autenthication Nina Salamah; Any Guntarti; Laela Hayu Nurani
Pharmaciana Vol 13, No 1 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Halal medicine is an interesting topic to always discuss because it is a priority choice for Muslim consumers, one of which is halal capsules. Currently, molecular biology techniques such as real-time polymerase chain reactions are rapidly developing, including for the analysis of non-halal components based on DNA sequences. This study aimed to validate the quantitative PCR method for identifying DNA in gelatin-based products and to apply the confirmation method designed for capsule samples on the market circulating in Yogyakarta to prove the halalness of these samples. Validation of the porcine DNA detection analysis method on standard extraction of porcine gelatin using primer pairs obtained in previous studies. Validated methods are used for testing market capsule shells. The qPCR method using D-loop primers is specifically capable of amplifying porcine gelatin DNA up to a concentration of 0.5 pg/µL, with a CV value in the amplification response of porcine gelatin DNA isolates (1000 pg/µL) of 0.85% which meets the test criteria using the PCR. Three samples of commercial soft capsules tested gave a positive amplification response, meaning that the samples tested contained porcine DNA, and one negative sample, which probably had non-porcine gelatin. The application of this method is also very useful for ensuring the authenticity of the capsule shell, especially from cross-contamination and counterfeiting.

Cytotoxicity of Zingiber officinale var. rubrum on HeLa cells and prediction of anti-proliferative activity via the jak2/stat3 and hedgehog pathways using a molecular docking approach Siti Rofida; Laela Hayu Nurani; Dwi Utami; Citra Ariani Edityaningrum
Pharmaciana Vol 13, No 3 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v13i3.27482

Cervical cancer is one of the second-leading causes of death in women. The discovery of cancer drug candidates continues to be carried out due to the resistance that occurs in cervical cancer therapy. Plant metabolite compounds are one of the sources used to explore new drug candidates. Red ginger rhizome is a candidate plant that has anti-cervical cancer activity. This study aims to determine the cytotoxicity of an ethanol extract of red ginger rhizomes on the growth of HeLa cancer cells and predict anti-proliferative activity via the jak2/stat3 and hedgehog pathways. The sample (red ginger rhizome simplicia) was extracted by remaceration using 75% ethanol. The MTT assay method is used to test the cytotoxicity and anti-proliferation of metabolite compounds using Autodock 4.2 software. The receptors used in the jak2, stat3, and smo pathways were obtained from the Protein Data Bank with the codes 6VGL, 6NUQ, and 5L7I, respectively. The ethanol extract produced is a thick yellowish brown extract with an aromatic smell and spicy taste, with an extract yield of 18.63% w/w. 75% ethanol extract of red ginger rhizomes has cytotoxic activity in HeLa cancer with an IC50 of 104.22 ± 6.18 µg/mL and an IC50 of cisplatin of 38.61 ± 3.66. Prediction of antiproliferative activity via the jak2 pathway shows a binding energy and Ki value of -7.47 kcal/mol, -7.48 kcal/mol, and 3.33 uM, 3.27 uM, as shown by alpha-cedrol and beta-eudesmol compounds. The highest inhibition on the stat3 and smo pathways was shown by the beta compound eudesmol, with binding energy and Ki values of -6.05 kcal/mol, -7.57 kcal/mol, and 36.48 uM, respectively; 2.81 uM.

Co-Authors Abdul Rohman Abdul Rohman Abdul Rohman Abdul Rohman Achmad Mursyidi Achmad Mursyidi Afiana Rohmani Agitohutomo, Muhammad Ainiyah, Nadia Putri Aisyah, Vani Aisyah, Vani Akrom Akrom, Akrom Aldri Frinaldi ANDI WIJAYA Anggita Rosiana Putri Anjar Windarsih Annisa Fatmawati Any Guntarti Any Guntarti Any Guntarti Any Guntarti Any Guntarti Arif Santoso Aris Asahi Aristiani, Windi Aristiani, Windy Astuti, Ratih Arum Azzahra, Fara Bachri, Mochammad Saiful Citra Ariani Edityaningrum, Citra Citra Dhea Cantika Danang Prasetyaning Amukti Daru Estiningsih Daud, Intan Devi Kumala Dewi Dewi Andini Kunti Mulangsri, Dewi Andini Kunti Dewi, Devi Kemala Dian Prasasti Djannah, Sitti Nur Djannah, Sitti Nur Dwi Utami Edityaningrum, Citra Ariyani Efiana, Nuri Ari Eka Kumalasari Eka Kumalasari Eka Kumalasari Eka Sakti Wahyuningtyas Eka Wahyuning Tyas Elya Zulfa, Elya Endang Darmawan Eti Nurwening Sholikhah Eti Nurwening Sholikhah Fara Azzahra Fara Azzahra Fauziyya, Riri Feri Anggita Hastanto Feri Anggita Hastanto Fikri Achmad Arif Fitriyati, Laeli Galih Dwi Mulyati Gela Setya Ayu Putri Hari Susanti Heni Lutfiyati, Heni Heni Setyowati Esti Rahayu Hidayati, Sholihatil Husnun Khairunnisa Pratiwi Ibnu Gholib Gandjar Ibnu Gholib Gandjar Ibnu Gholib Gandjar Ichsan Luqmana Indra Putra, Ichsan Luqmana Indra Ichwan Ridwan Rais Iin Narwanti Iin Narwanti Iis Wahyuningsih Intan Rahayu Irfan, Nawwar Irnawati Irnawati Isabella Meliawati Sikumbang Isabella Meliawati Sikumbang Jumina Jumina Jumina Jumina Kartikadewi, Arum Khairurrizki, Amanda Khayatulisma, Dika Kurnianto, Erwan Lalu Muhammad Irham Mahardika Agus Wijayanti Ma’ruf, Muhammad Meta Safitri Milanie, Rida Dwi Miratun Syarifah Moch Saiful Bachri Moch. Saiful Bachri Moch. Saiful Bachri Moch. Saiful Bachri Muhammad Fikri Muhammad Ma'ruf Muhammad Yusron Maulana El-Yunusi Mustofa Mustofa Nanik Sulistyani Nasruddin Nasruddin Nasruddin Nasruddin Nasruddin, N Nina Salamah Nining Sugihartini Nining Sugihartini Nugrahini, Febrina Nur Azizah Nur Ismiyati Nurkhasa Nurkhasa, Nurkhasa Nurkhasanah Nurkhasanah Mahfudh Nurkhasanah Nurkhasanah Putri Kurniasiwi Putri Lestari Rahma Dona Ramadhan, Muhammad Marwan Rini Sulistyawati Rizki Amelia Rohman, Abdul Salsabila, Nia Sapto Yuliani SATRIYAS ILYAS Sikumbang, Isabella Meliawati Sitarina Widyarini Sitarina Widyarini Siti Fatmawati Fatimah, Siti Fatmawati Siti Rofida Siti Salma Yusuf Siti Setianingsih Sitti Nur Djannah Sudjadi . Sugiyanto - Sulistyorini, Dwi Agustin Suwidjiyo Pramono Syarif, Yaumi Musfirah Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tri Ani Marwati Tri Yanuarto Tria Zakinah Utari, Dina Vani Aisyah Vivi Sofia Wahyu Widyaningsih Wahyuningtyas, Nurma Widea Rossi Desvita Widyarini, Sitarina Wihasty Nur Istyqomah Wiwara Awisarita Yaumi Musfirah Syarif Yeni Dianita Yeni Yeni, Yeni Dianita Yeni, Yeni Dianita Yoga Yuniadi Yusuf, Siti Salma Zainab Zainab Zainab Zainab

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