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PENENTUAN TINGKAT AKTIFITAS CHOLINESTERASE DARAH YANG KEBIASAAN MENGGUNAKAN OBAT ANTINYAMUK BAKAR PADA PENDUDUK KELURAHAN JATI PADANG Elmatris Sy; Yustini Alioes; Miftah Irramah
Jurnal Riset Kimia Vol. 4 No. 2 (2011): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v4i2.129

Abstract

 ABSTRACTThis study aims to determine the level of blood cholinesterase activity using a drug habit antinyamuk fuel (OANB), in Kelurahan Jati Padang and analyzed at the Laboratory of Biochemistry at the Faculty of Medicine in April-November 2010. The population is all residents Jati Padang village. The sample is using drugs antinyamuk fuel that is 30 people with sampling techniques eccidental sampling, as control is a resident who does not use drugs antinyamuk (Joan). The results showed: the population of 74 people who came, in getting 30 people to use OANB, 39 people who do not use OANB (liquid and lotion), 5 people who did not use Joan (as control). The average level of blood cholinesterase activity using OANB is 7294.79 u / l, and that does not use Joan is 7645.97 u / l. In conclusion, the average level of blood cholinesterase activity in the population there is a tendency Kelurahan Jati Padang cholinesterase activity levels decreased when compared to controls. Decrease in the average value of cholinesterase activity and a decrease of 5% is still within normal limits. Keywords: drug antinyamuk fuel, cholinesterase   
PENGARUH MEROKOK TERHADAP LAJU ALIRAN SALIVA Lisma Yendri; Surya Nelis; Yustini Alioes
Jurnal Kesehatan Gigi Vol 5, No 2 (2018): Desember 2018
Publisher : Jurusan Keperawatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v5i2.3860

Abstract

TITLETHE EFFECT OF SMOKING TO SALIVARY FLOW RATEABSTRACTSmoking is a habbit which is commonly found and it is the biggest threat for future world’s health. Nicotine is toxic components that is the most widely contained in cigarette. Prolonged exposure to nicotine on salivary gland is a causative factor of pathological processes or morphological and functional abnormalities of salivary gland, especially acinar cells and myoepithelial cells. The purpose of research to know the representation salivary flow rate smokers and the influence of smoking duration and number of cigarettes which are smoked to the salivary flow rate. This study was an analytical survey with cross sectional design. Total samples  90 persons were taken proportionally and divide into 9 criteria. Collecting unstimulated salivary used spitting method. Data analysis used  the krusskal-wallis test and pos hoc mann-whitney.The mean (SD±) salivary flow rate were 0,36 (±0,207) ml/min in smokers and  krusskal-wallis test to looked the influences of salivary flow rate  showed a value of  p 0,05 (p=0,012). The study showed that there were significant influence between smoking duration and number of  cigarettes which are smoked with the salivary flow rate.
UJI POTENSI ANTIJAMUR CANDIDA ALBICANS EKSTRAK DAUN GELINGGANG (CASSIA ALATA L.) DIBANDINGKAN DENGAN SEDIAAN DAUN SIRIH YANG BEREDAR DI PASARAN SECARA IN VITRO Yustini Alioes; amalia Kartika
Jurnal Kimia Riset Vol. 3 No. 2 (2018): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (509.178 KB) | DOI: 10.20473/jkr.v3i2.12040

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ABSTRAK           Candida albicansmerupakan salah satu contoh mikroorganisme patogenik penyebab infeksi pada bagianlumenorgan tubuh manusia yang berbentuk saluran. Candida albicanspada saluran reproduksi dan saluran urinaria wanita sering dikenal dengan “penyakit keputihan”. Salah satu cara mengatasi munculnya keputihan adalah dengan membersihkan daerah kewanitaan menggunakan larutan antiseptik seperti povidone iodine. Masyarakat pada umumnya juga menggunakan sediaan daun sirih yang telah beredar di pasaran. Sediaan ini juga dikenal sebagai antiseptik sehingga dapat menghambat pertumbuhan C. Albicans,selain daun sirih (Piper bitleL.), ternyata daun gelinggang atau ketepeng cina (Cassia alataL.) juga memiliki aktivitas antibakteri dan antijamur.           Penelitian ini merupakan penelitian eksperimental dengan menggunakan isolat jamur C.albicans. Proses ekstraksi daun gelinggang dilakukan dengan teknik maserasi menggunakan pelarut metanol, alkohol 96%, dietil eter, dan infusa. Ekstrak dan SDS diuji aktivitas antijamurnya dengan menggunakan metode difusi agar menggunakan kertas cakram. Analisis uji ini dilakukan dengan mengukur zona hambatan ekstrak dan sediaan daun sirih terhadap pertumbuhan jamur.          Analisis nilai persentase aktivitas zona hambat ekstrak metanol daun C.alata menunjukkan tidak adanya perbedaan yang signifikan dengan SDS 1 (asymp. Sig.= 0,245) dan dengan SDS 2 (asymp. Sig. = 0,882) dalam menghambat pertumbuhan jamurC.albicans.Ekstrak metanol daun gelinggang memiliki efektifitas yang hampir sama dengan dua kelompok perlakuan SDS yang beredar di pasaran(SDS 1 dan SDS 2).Kata kunci: Antijamur, Candida albicans, sediaan daun sirih (SDS), ekstrak daun Gelinggang (Cassia alata L.). ABSTRACT Candida albicans is one of pathogenic microorganisms that cause infections in the lumen of the organs of human body in the shape of the channel. Candida albicans in the reproductive tract and women urunaria tract is often known as "diseases of vaginal discharge". One way of overcoming the appearance of vaginal discharge is to clean the area using an antiseptic solution of femininity such as povidone iodine. Society in General also use material of betel leaf that has been circulating in the market. This material is also known as an antiseptic so that it can inhibit the growth of C. albicans. In addition to the betel leaf (Piper bitle l.), turns the leaves gelinggang or Chinese ketepeng (Cassia alata L.) also has antibacterial and antifungal activity.             The objective of this study was to compare the test potential antifungal Candida albicans gelinggang leaves (Cassia alata L.) with material of betel leaf that already circulating in the market(SDS).This research is experimental research using fungal isolates of C. albicans. The extraction process of leaf gelinggang done with the technique of maceration using methanol solvent, 96% alcohol, diethyl ether, and infusa. Extract and SDS tested of antifungal activity by using diffusion method using paper discs. The analysis of the test is done by measuring the resistance zone extracts and preparations betel leaf against mold growth.         The analysis of the value of the percentage of the activity of the methanol extracts of the leaves of the inhibitory zones c. alata indicates the absence of a significant difference with the SDS 1 (asymp. Sig. = 0.245) and with SDS 2 (asymp. Sig. = 0.882) in inhibiting the growth of c. albicans yeast.The methanol extract of gelinggang leaves treatment has effectiveness similar to the treatment of the two groups of SDS (SDS 1 and SDS 2) that is circulating in the market.Keywords: Antifungal preparations, Candida albicans, Betel leaf (SDS), Gelinggang leaf extract (Cassia alata L.).
UPAYA PENINGKATAN PENGETAHUAN TENTANG MAKANAN JAJANAN DAN PEMERIKSAAN GOLONGAN DARAH PADA MURID SD NEGERI 11 LOLONG BELANTI DI KECAMATAN PADANG UTARA Yustini Alioes; Husnil Kadri
BULETIN ILMIAH NAGARI MEMBANGUN Vol 3 No 1 (2020)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (800.637 KB) | DOI: 10.25077/bina.v3i1.168

Abstract

Community service on the decision-making process in foreign policy aims to improve awareness of high school students in Padang on the importance of foreign policy. Foreign policy is often identified with complexity and far from public sphere. The community service team expects this activity could help high school students understand the decision making process in foreign policy. The community service is conducted with lecture and role-play method of formulating foreign policy. The approach used in this program is Graham Allison’s concept regarding process of foreign policy- making. This activity is designed in several stages. In the initial stages, the team prepares working plans. The second stage is socialization and the last stage is program implementation. It can be concluded that this community service has increased the student’s understanding in regards to the importance of foreign policy. Result of this activity indicates that students’ knowledge on foreign policy is improving. This is calculated based on several indicators i.e understanding on the role of actors in formulating foreign policy, factors affecting foreign policy and impact on the state’s strategy to pursue its national interest.
EDUKASI KESEHATAN DAN PEMERIKSAAN GOLONGAN DARAH PADA MURID SD NEGERI 13 DI DESA TUNGKAL SELATAN KECAMATAN PARIAMAN UTARA Yustini Alioes; Husnil Kadri; Eti Yerizel; Hirowati Ali; Rauza Sukma Rita; Desy Arisanti
BULETIN ILMIAH NAGARI MEMBANGUN Vol 4 No 2 (2021)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v4i2.289

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Elementary school students are consumers who are among those who consume the most food and beverages. Food and drinks sold around the school contain many hazardous substances such as dyes that have been banned from circulating (Rhodamine B in iced drinks, jelly drinks, and so on) and other additives such as formalin which is used as a chewy substance in meatballs sold in carts and restaurants that can cause acute poisonings such as allergies, coughs and chronic poisonings such as cancer of the liver, kidneys and other organs. The purpose of this activity is to increase knowledge about substances in food and an introduction to blood group examination. This activity was carried out at SD Negeri 13 Tungkal Selatan Village in North Pariaman District. The method of activity is in the form of counseling and demonstration. According to the survey before the blood group examination, it turned out that most of the elementary school students did not know their blood type. Before the blood group examination, the students were also given knowledge about determining a person's blood type. After this counseling was carried out, respondents became more aware of the impact of food/snacks on health, and respondents knew their respective blood types. Of the 64 students, there are 22 A, 17 B, 12 AB, 13 O. To avoid problems related to food and blood type. There is a need for continuous health education for elementary school students.
EFEK PEMBERIAN VITAMIN E TERHADAP JUMLAH ERYTROSIT DAN AKTIVITAS ENZIM KATALASE TIKUS AKIBAT PAPARAN SINAR ULTRAVIOLET Yustini Alioes; Elmatris Sy
Majalah Kedokteran Andalas Vol 33, No 2: Agustus 2009
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.221 KB) | DOI: 10.22338/mka.v33.i2.p%p.2009

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AbstrakSinar ultra violet (UV) selain mempunyai dampak positif terhadap kesehatan, UV juga dapat membahayakan kesehatan. Dampak negatif UV ini dirasakan oleh orang-orang yang terpapar sinar UV dalam jangka waktu lama, seperti nelayan dan petani. Radiasi UV tingkat sedang menyebabkan kulit kemerahan (eritema), sedangkan tingkat tinggi dapat menyebabkan perdarahan pada kulit.Penelitian ini bertujuan untuk mengetahui efek pemberian vitamin E terhadap jumlah erytrosit dan aktifitas enzim katalase tikus akibat paparan sinar ultra violet. Penelitian ini bersifat eksperimental dengan menggunakan tikus sebagai hewan coba, yang dilakukan di Laboratorium Biokimia Fakultas Kedokteran Universitas Andalas dari bulan September – Desember 2008. Populasi adalah 20 ekor tikus galur Wistar, umur ± 2 bulan dan berat badan 200-250 gram. Sampel diambil secara acak (simple random sampling) dari populasi dan dibagi menjadi dua kelompok yaitu : Kelompok kontrol (Kelompok yang diradiasi UV 6 jam/hari selama 3 minggu tanpa pemberian vitamin E) dan kelompok perlakuan (Kelompok yang diradiasi UV 6 jam/hari selama 3 minggu dengan pemberian vitamin E dosis 0.45 IU/kg BB/1 kali/hari). Hasil penelitian menunjukkan pada kelompok kontrol terjadi penurunan jumlah erytrosit dan aktifitas enzim katalase akibat paparan sinar UV. Jumlah Penurunan ini akan lebih sedikit setelah pemberian vitamin E.Efek pemberian vitamin E dapat menghambat penurunan jumlah erytrosit dan aktivitas enzim katalase tikus yang terpapar sinar ultraviolet.Kata Kunci : VitaminE, Erytrosit, KatalaseAbstract Ultraviolet (UV) in addition to having a positive impact on health, UV can also endanger your health. UV negative impact is felt by the people who are exposed to UV light for long periods, such as fishermen and farmers. UV radiation levels are causing skin redness (erythema), whereas high levels can cause bleeding in the skin. This study aims to determine the effect. These are experimental studies using rats as an animal, which conducted the Biochemistry Laboratory of the Faculty ofARTIKEL PENELITIAN128Medicine University of Newcastle from September - December 2008. Population is 20 strains of Wistar rats, age ± 2 months and weight 200-250 grams. Samples taken at random (simple random sampling) of the population and divided into two groups: control group (group UV irradiated 6 hours/day for 3 weeks without vitamin E) and the treatment group (group UV irradiated 6 hours/day for 3 weeks with doses of vitamin E 0:45 IU/kg BB/1 kali/day). The results showed in the control group declines erytrosit and catalase enzyme activity due to exposure to UV. decline was much less after vitamin E. Conclusion: The effect vitamin E can inhibit the decrease in the number erytrosit and catalase enzyme activities of rats exposed to ultraviolet light.of vitamin E on the number of erytrosit and catalase enzyme activities of rats by exposure to ultraviolet light.Key words : Vitamin E, Erytrosit, Katalase
EFEK PENGGUNAAN ZAT PEWARNA Erythrosine TERHADAP KADAR T3 DAN T4 SERUM PADA TIKUS GALUR WISTAR Asterina Asterina; Elmatris Sy; Yustini Alioes
Majalah Kedokteran Andalas Vol 35, No 2 (2011): Published in August 2011
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (494.187 KB) | DOI: 10.22338/mka.v35.i2.p126-136.2011

Abstract

AbstrakZat pewarna sintetis erythrosine berdasarkan struktur kimianya terkandung senyawa yodium, maka dapat dikatakan secara substansial asupan makanan yang mengandung erythrosine merupakan asupan yodium. Penggunaan zat pewarna erythrosine dalam waktu lama dan kadar diatas ambang batas tentu akan memberikan kontribusi kelebihan asupan yodium dan akan berdampak terhadap kadar T3 dan T4 dalam serum.Penelitian ini bertujuan untuk mengetahui Efek Penggunaan Zat Pewarna Erythrosine terhadap Kadar T3 dan T4 Serum pada Tikus galur Wistar, yang dilakukan dari bulan April sampai bulan November 2010. Penelitian ini dilakukan di laboratorium Farmasi Unand dan Laboratorium Biokimia Fakultas Kedokteran Unand . Jenis penelitian yang digunakan adalah Eksperimental dengan jumlah sampel sebanyak 21. Hasil penelitian menunjukan terdapat kecendrungan penurunan T3 dan T4. Kesimpulan : terdapat efek pemberian Erythrosine 300 ppm, 600 ppm hingga 1% pada waktu 3 minggu terhadap kadar T3 dan T4, secara statistic terdapat penurunan yang bermakna dengan nilai p = 0,018 dan p = 0,012 bila dibandingkan dengan kontrol. Tidak terdapat pengaruh lama waktu paparan zat pewarna erythrosine terhadap nilai T3, yang secara statistic tidak terdapat penurunan yang bermakna dengan p = 0,062, bila dibandingkan terhadap kontrol. Terdapat pengaruh lama waktu paparan zat pewarna erythrosine terhadap nilai T4 , yang secara statistic terdapat penurunan yang bermakna dengan p = 0,041, bila dibandingkan terhadap kontrol.Kata kunci : Erythrosine , T3, T4AbstractThe synthetic dyes, erythrosine based on their chemical structure contain iodine compound, then they can be said substantially as food intake containing erythrosine is iodine uptake. The utility eryhthrosine in a long time with certain over thres hold will provide to contribute iodine uptake exceed and impact to serum T3 and T4.This research aim to know the effect of using erythrosine dye to serum T3 and T4 in Galur Wistar mice, performed from April to November 2010. This research is performe in Laboratory of Farmacy of Andalas University and Biochemical laboratory of Medical Faculty, Andalas University. Type of study used isARTIKEL PENELITIAN127Experimental study with 21. samples. Result indicate that there is tendency of decreasing T3 and T4.Conclusion: there are administering effect of 300 ppm, 600 ppm Erythrosine until 1% for three weeks to T3 and T4, respectively. Statistically, there are significantly decreasing with value p = 0,018 and p = 0,012 respectively, than control. There is not effect of expose time of Erythrosine to T3, which statistically is no significantly declining by p =0,062, than control. There are effect of expose time of eryhrosine to T4 level, which statistically there is declining significantly with p = 0,041, than control.Key word : Erythrosine, T3, T4.
HUBUNGAN PENYAKIT GONDOK DENGAN KADAR YODIUM DALAM URIN MURID MADRASAH IBTIDAIYAH NEGERI (MIN) KORONG GADANG KECAMATAN KURANJI KOTA PADANG Yustini Alioes
Majalah Kedokteran Andalas Vol 34, No 2 (2010): Published in August 2010
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.388 KB) | DOI: 10.22338/mka.v34.i2.p184-192.2010

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AbstrakYodium adalah komponen esensial dalam asupan makanan manusia, yang merupakan bagian dari hormone tiroid yaitu tiroksin (T4) and triiodotironin (T3). Hormon tersebut dibutuhkan untuk menjaga metabolism basal, metabolism sel, dan kesatuan jaringan tubuh. Hormone tiroid diperlukan dalam perkembangan system sarat janin dan bayi. Kekurangan asupan yodium dapat menyebabkan penyakit gondok, yaitu pembesaran kelenjar tiroid. Gondok endemic merupakan hasil dari peningkatan kerja kelenjar tiroid oleh Thyroid Stimulating Hormone (TSH) dalam memaksimalkan penggunaan yodium yang tersedia, hal ini merupakan penyesuaian terhadap kekurangan yodium.Tujuan penelitian ini adalah untuk mengetahui hubungan penyakit gondok dengan kadar yodium dalam urin murid Madrasah Ibtidaiyah Negeri Korong Gadang Kecamatan Kuranji Kota Padang.Telah dilakukan penelitian pada 130 murid kelas II, III, IV, V dan VI di Madrasah Ibtidaiyah Negeri (MIN) Korong Gadang Kecamatan Kuranji Kota Padang. Data tentang prestasi belajar didaptkan dari hasil ujian semester. Pertumbuhan fisik ditentukan berdasarkan berat badan dan tinggi badan.Selama penelitian ini didapatkan 80 anak (61,5%) menderita penyakit gondok. Tidak didapatkan hubungan yang bermakna antara penyakit gondok dan kadar yodium dalam urin (p>0,05). Penelitian ini juga menemukan tidak terdapat hubungan antara penyakit gondok dan pertumbuhan fisik (p>0,05).Kata Kunci : Iodium, urin, hipertiroidAbstractIodine is an essential component of human diet, which part of thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones are involved in the maintenance of metabolic rate, cellular metabolism and integrity of connective tissue. Thyroid hormones are necessary for the development of nervous system in the fetus and infant. Lack of dietary iodine is cause of goiter, an enlargement of the thyroid stimulating hormone (TSH) to maximize the utilization of available iodine and thus respresents maladaption to iodine deficiency.The aim of this study was to investigate the relation between goiter with academic performance and urinary excretion iodine of children in Madrasah Ibtidaiyah Negeri (MIN) in Korong Gadang Kuranji District, Padang City.ARTIKEL PENELITIAN185A cross sectional study has been done in 130 students of the second, third, fourth, fifth, and sixth degree of Madrasah Ibtidaiyah Negeri (MIN) Korong Gadang Kecamatan Kuranji Padang City. Data of academic performance was taken from the result of study in a semester. Physical growth was determined based on weight and height.During the research, there were 80 children (65,1%) who suffered from goitre. The correlation between goitre and academic performance are unsignificant (p>0,05). This study was also found that there was no correlation between goitre and physical growth (p>0,05).Key Word : Iodine, urine, hyperthyroidism
PEMERIKSAAN DAYA HAMBAT EKTRAK METANOL DAUN TRISTANIA SUBAURICULATA KING TERHADAP PERTUMBUHAN KUMAN PSEUDOMONAS AERUGINOSA DAN STAPHYLOCOCCUS AUREUS Yustini Alioes; Benni Raymond
Majalah Kedokteran Andalas Vol 35, No 1 (2011): Published in April 2011
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (419.33 KB) | DOI: 10.22338/mka.v35.i1.p37-42.2011

Abstract

AbstrakTristania subauriculata King dikenal oleh penduduk sekitar Kelok Sembilan, Payakumbuh sebagai obat untuk mengobati penyakit kulit. Diduga Tristania subauriculata King mengandung suatu senyawa bioaktif yang bersifat sebagai anti bakteri.Untuk melihat efektifitas ekstrak metanol daun Tristania subauriculata King dalam menghambat pertumbuhan kuman Pseudomonas aeruginosa dan Staphylococcus aureus, telah dilakukan penelitian secara invitro dengan menggunakan metode difusi agar, pengamatan dilakukan dengan mengukur diameter daerah hambat yang terbentuk pada agar.Dari penelitian didapatkan adanya daya hambat ekstrak metanol daun Tristania subauriculata King 15% b/v dalam menghambat pertumbuhan kuman Pseudomonas aeruginosa dan Staphylococcus aureus. Daya hambat ini meningkat pada konsentrasi 30% b/v, 45% b/v, dan daya hambat terbesar pada konsentrasi 60% b/v yang terlihat dengan semakin besarnya diameter daerah bebas kuman yang dihasilkan.Kata kunci : Ekstrak Metanol daun Tristania subauriculata King, Diameterhambat, Pseudomonas aeruginosa dan Staphylococcus aureusAbstractTristania subauriculata King has been known by the people of Kelok Sembilan, Payakumbuh as the medicine to cure dermatopathy. It is thought that Tristania subauriculata King contains a bioactive constituent which acts as anti bacteria.To figure the effects of methanol extract of Tristania subauriculata King in holding the growth of Pseudomonas aeruginosa and Staphylococcus aureus,an invitro observation has been done using difusion agar method. The observation was done by measuring the diameter of inhibition area that has been formed.From the observation, it is found that there is inhibition capacity of methanol extract of Tristania subauriculata King 15% b/v in holding the growth ofARTIKEL PENELITIAN38Pseudomonas aeruginosa and Staphylococcus aureus. This inhibition capacity increase on the concentration of 30% b/v, 45% b/v, and the biggest inhibition capacity is on the concentration of 60% b/v which can be seen with the increase of inhibition zone.Key word: Folium Tristania subauriculata King extract metanol, Diameterhambat, Pseudomonas aeruginosa and Staphylococcus aureus
HUBUNGAN PENYAKIT GONDOK DENGAN PRESTASI BELAJAR DAN TINGGI BADAN ANAK MADRASAH IBTIDAIYAH NEGERI (MIN) KORONG GADANG KECAMATAN KURANJI KOTA PADANG Yusri Dianne Jurnalis; Yustini Alioes; Prima Julistia
Majalah Kedokteran Andalas Vol 32, No 2: Agustus 2008
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (92.961 KB) | DOI: 10.22338/mka.v32.i2.p%p.2008

Abstract

AbstrakYodium adalah komponen esensial dalam asupan makanan manusia, yang merupakan bagian dari hormon tiroid yaitu tiroksin (T4) and triyodotironin (T3). Hormon tersebut dibutuhkan untuk menjaga metabolisme basal, metabolisme sel, dan kesatuan jaringan tubuh. Hormon tiroid diperlukan dalam pekembangan sistem saraf janin dan bayi. Kekurangan asupan yodium dapat menyebabkan penyakit gondok, yaitu pembesaran kelenjar tiroid. Gondok endemik merupakan hasil dari peningkatan kerja kelenjar tiroid oleh Thyroid Stimulating Hormone (TSH) dalam memaksimalkan penggunaan yodium yang tersedia, hal ini merupakan penyesuaian terhadap keku-rangan yodium. Gangguan paling parah yang dapat disebabkan oleh kekurangan yodium adalah retardasi mental yang menetap dan hambatan pertumbuhan. Selama kurun wktu 5 tahun, prevalensi penyakit gondok di Kota Padang meningkat dari 8,5% menjadi 21,5%.Tujuan penelitian ini adalah untuk mengetahui prevalensi penyakit gondok dan hubungannya dengan prestasi belajar dan tinggi badan anak Madrasah Ibtidaiyah Negeri (MIN) Korong Gadang Kecamatan Kuranji Kota Padang.Telah dilakukan penelitian pada 169 murid kelas II, III, IV, V, dan VI di Madrasah Ibtidaiyah Negeri (MIN) Korong Gadang Kecamatan Kuranji Kota Padang. Data tentang prestasi belajar didapatkan dari hasil ujian semester. Tinggi badan ditentukan berdasarkan tinggi badan per umur.Selama penelitian ini didapatkan 84 anak (49,7%) menderita penyakit gondok. Tidak didapatkan hubungan yang bermakna antara penyakit gondok dan prestasi belajar (p>0,05). Penelitian ini juga menemukan tidak terdapat hubungan antara penyakit gondok dan pertumbuhan fisik (p>0,05).Kata kunci : Penyakit Gondok, Prestasi Belajar, Tinggi Badan AnakAbstractIodine is an essential component of human diet, which part of thyroid hormones, thyroxine (T4) and triiodothyronine (T3). These hormones are involved in the maintenance of metabolic rate, cellular metabolism and integrity of connective tissue. Thyroid hormones are necessary for the development of nervous system in the fetus and infant. Lack of dietary iodine is cause of goitre, an enlargement of the thyroidARTIKEL PENELITIAN161gland. Endemic goiter results from increased thyroid stimulation by thyroid stimulating hormone (TSH) to maximize the utilization of available iodine and thus respresents maladaption to iodine deficiency. However, the most damaging disorders induced by iodine deficiency are irreversible mental retardation and growth restriction. Within 5 years, prevalence of goitre in Padang City increased from 8.5% to 21.5%.The aim of this study was to investigate the prevalence of goiter and its relation with academic performance and stature of Madrasah Ibtidaiyah Negeri (MIN) students in Korong Gadang Kuranji District, Padang City.A cross sectional study has been done in 169 students of the second, third, fourth, fifth, and sixth degree of Madrasah Ibtidaiyah Negeri (MIN) Korong Gadang Kuranji District, Padang City. Data of academic performance was taken from the result of study in a semester. Stature was determined based on height for age.During the research, there were 84 children (49.7%) who suffered from goitre. The correlation between goitre and academic performance are unsignificant (p>0.05). This study was also found that there was no correlation between goitre and physical growth (p>0.05).Keywords: Goitre, Academic Performance, Child Stature
Co-Authors Adrial Adrial, Adrial Aida Fitriana Aliya, Lisana Shidiqqin Almurdi Almurdi amalia Kartika Amelia Amelia Amirah Zatil Izzah Ananda, Abi Awfa Rahman Andree, Azzahra Anggita Anggraini, Syahzalya Anggrainy, Fenty Annisa Pratiwi Asterina Asterina Asterina, Asterina Ayu Ratna Sari Azzati, Normaida Baizura Benni Raymond Catur Hadi Arief Dermawan Chindy Jhonel Putri Deddy Saputra Desmawati Desmawati Desmawati Desmawati Dessy Arisanty Desy Arisanti Desy Arisanti Dia Rofinda, Zelly Dia Dian Pertiwi Dinda Aprilia Dwi Yulia Efendi, Altio Efendi, Altio Efrida Efrida Elmatris Sy Elmatris Syamsir Elsi Wineri Endrinaldi Endrinaldi , Endrinaldi Eni Rahmi Eti Yerizel Eva Chundrayetti Eva Decroli F, Annisa Maida Fadil Oenzil Fadrian, Fadrian Faradila Faradila Fika Tri Anggraini Harsa Rusda Hasibuan, Imron Martua Hasnah Hasnah Hasnah, Hidayatul Hasnah, Widya Jummatul Hayyumahdania Reswan Hendra Permana Hirowati Ali Husnil Kadri Husnil Wardiyah Indah Febranambela Jovie Irwan Jamsari Jamsari Kartika, amalia Lili Irawati Lily Syukriani Lisma Yendri Lydia Susanti, Lydia M Ikhsan Mahata, Liganda Endo Mentari Artika Merisca Gayatri Ryosa Meska Amelia Putri Miftah Irrahmah Miftah Irramah Murniwati Murniwati Mutya Restu Ayu Nila Kasuma Nining Kurniawati Nurhayati Nurhayati Nursyafi, Fauzan Syarif Prasetio, Ade Prima Astuti Handayani Prima Julistia Pritasa Muthia Ulfa Putri Mira Magistri Putri Mulya Sari Putri, Biomechy Oktomalio Rahmatini . Raihan Afif Salam Ramadhan, Mario Arya Ramadhan, Mario Arya Rauza Sukma Rita Reza, Mohamad Rikarni Rikarni Rima Semiarty Risa Firka Rismawati Yaswir Roslaili Rasyid Rydwan Efendi Saptino Miro Saptino Miro, Saptino Selfi Renita Rusjdi Sheila Jihan Safira Sofina Rusdan Suci Erawati Surya Nelis Susi Susi Susila Sastri Tafdil, Zhafirah Khairunnisa Yenny Mayang Sari Yulia, Dwi Yusri Dianne Jurnalis Yusri, Elfira