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All Journal Journal of Food and Pharmaceutical Science Pharmaciana: Jurnal Kefarmasian Harmoni Sosial: Jurnal Pendidikan IPS Jurnal Terapan Abdimas Al-Jabar : Jurnal Pendidikan Matematika Jurnal Farmasi Sains dan Komunitas Jurnal Mercumatika : Jurnal Penelitian Matematika dan Pendidikan Matematika Syntax Literate: Jurnal Ilmiah Indonesia Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Ilmu Kefarmasian Indonesia Jurnal Mandala Pharmacon Indonesia Pharmacoscript Jurnal Ilmiah Cendekia Eksakta Indonesian Journal of Global Health research Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Pengabdian Masyarakat Multidisiplin Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Kajian Ilmiah Prima Abdika: Jurnal Pengabdian Masyarakat Journal La Lifesci Jurnal Penelitian Inovatif Indo-MathEdu Intellectuals Journal International Journal of Islamic and Complementary Medicine Journal Of Human And Education (JAHE) Jurnal Bakti Untuk Negeri Duta Pharma Journal Jurnal Katalisator Journal of Food and Pharmaceutical Sciences Riemann : Research of Mathematics and Mathematics Education Journal of Educational Research and Practice Jurnal Farmasi Galenika Contemporary Education and Community Engagement JI-KES (Jurnal Ilmu Kesehatan) Folia Medica Indonesiana
Kintoko Kintoko
Prodi Magister Pendidikan Matematika, Pascasarjana, FKIP – UNS
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The Potency of Microalgae as a Marine Source: A Bibliometric Analysis Witasari, Hardi Astuti; Kintoko, Kintoko; Ahda, Mustofa; Rangkuti, Ahmad Faizal; Suhendra, Suhendra; Mahfudh, Nurkhasanah
Journal of Food and Pharmaceutical Sciences Vol 13, No 2 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.18870

Abstract

Microalgae were a marine source that was highly sustainable and offered numerous benefits in industrial applications. Many species were safe and effective as active ingredients in the food, cosmetics, and pharmacy industries and became raw materials for renewable energy, such as biofuel. The exploration of bioactive compounds was enticing for the research. The study of microalgae potency is a fascinating subject that deserves further exploration. The bibliometrics analysis can provide a good overview of microalgae research and its applications in industry. This overview was derived from the Scopus database, which contained all articles published between 1993 and 2023 with the keywords "microalgae" and "their application. Based on this discovery, many papers reported the potential of microalgae for antioxidants, nutrition, vaccine adjuvants, bioethanol, biofuel, and other applications for 2021-2022. This review criticizes the cultivation in a controlled environment up to the toxicity of microalgae. According to this review, many researchers focused and collaborated on exploring microalgae in the top three international journals, such as Algal Research, Marine Drugs, and Journal of Applied Phycology. Several countries, including Italy, Spain, and China, were the most focused on declaring the application of microalgae. The keywords described the core discussion and could be read generally and comprehensively. This bibliometric analysis was expected to contribute to developing microalgae for many applications.
Peran Program Adiwiyata dalam Pembentukan Karakter Peduli Lingkungan untuk Mendukung Mitigasi Bencana di Sekolah Menengah Pertama Kota Semarang Mulianingsih, Ferani; Kintoko, Kintoko; Permana, Septian Aji; Astuti, Andarweni; Suprapto, Yuni
Indo-MathEdu Intellectuals Journal Vol. 6 No. 4 (2025): Indo-MathEdu Intellectuals Journal
Publisher : Lembaga Intelektual Muda (LIM) Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54373/imeij.v6i4.3675

Abstract

This research aims to examine the integration of the Adiwiyata Program in the formation of an environmentally caring character as a disaster mitigation effort based on educational units. The research was conducted with a participatory approach at SMP Negeri 4 and SMP Negeri 29 Semarang through three main stages: planning, implementation, and evaluation. The results indicate an increase in student awareness and involvement in sustainable environmental management, active participation in green school programs, and a real role in building a culture of disaster preparedness. Character strengthening is carried out through habituation, exemplification, and integration of environmental materials into the curriculum. This strategy has proven effective in enhancing students' adaptability to disaster threats related to environmental damage, such as floods and landslides. These findings emphasize the importance of collaboration between character education and the implementation of the Adiwiyata Program to shape a school ecosystem
Peningkatan Kapasitas Guru IPS dalam Mitigasi Bencana Melalui Komik Edukasi Berbasis Deep Learning di Kota Semarang Mulianingsih, Ferani; Fajar, Fajar; Mumpuni, Restu Ayu; Kintoko, Kintoko
Indo-MathEdu Intellectuals Journal Vol. 6 No. 4 (2025): Indo-MathEdu Intellectuals Journal
Publisher : Lembaga Intelektual Muda (LIM) Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54373/imeij.v6i4.3682

Abstract

Disaster mitigation is a critical component in the field of education, particularly for Social Studies (IPS) teachers who play a strategic role in fostering students’ awareness of disaster risks. This community service program aims to enhance the capacity of Social Studies teachers in Semarang City to deliver disaster preparedness material through educational comics supported by deep learning technology. The program’s approach involves intensive training on the development of digital educational comics utilizing artificial intelligence to produce adaptive and interactive narratives. Teachers are guided to comprehend the fundamental principles of disaster mitigation, integrate deep learning into visual material development, and refine their pedagogical delivery techniques. This approach is expected to generate an interactive comic-based learning method that improves teachers’ understanding and engagement in disaster education. Furthermore, the application of deep learning allows for greater personalization of content tailored to the specific learning context. Therefore, this program holds potential as an innovative, technology-oriented model for sustainable disaster mitigation education.
Effectiveness of the Scramble Learning Model on Students' Ability to Understand Mathematical Concepts Aprilia, Dian; Kintoko, Kintoko; Siswanto, Deny Hadi
Contemporary Education and Community Engagement (CECE) Vol. 2 No. 1 (2025)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/cece.v2i1.1282

Abstract

This study aims to analyze the effectiveness of the use of the Scramble type cooperative learning model on the mathematical concept understanding ability of class VII students of Muhammadiyah 1 Mlati Junior High School: A Quasi-experimental Study with a Posttest Only Control Design consisting of two groups, namely the experimental class treated with the Scramble learning model (VII-B with 30 students) and the control class using conventional learning (VII-C with 30 students). The results of this study indicate that the sig. 2-tailed 0.000 < 0.05, which indicates a significant effect of the application of the Scramble model on the understanding of mathematical concepts. This study provides an important contribution to the development of more innovative mathematics teaching methods, where the implementation of learning from the teacher's side is quite high, namely 97.91% with an excellent category, while the implementation of learning by students reaches 96.15% with an excellent category.
Uji Toksisitas Akut Ekstrak Daun Sirih Keraton (Cissus discolor) Yang Berpotensi Sebagai Obat Antihipertensi Rohma, Siti; Kintoko, Kintoko; Utami, Dwi
Duta Pharma Journal Vol. 4 No. 2 (2024): DUTA PHARMA JOURNAL
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/ffx93a96

Abstract

Tanaman yang diketahui memiliki potensi sebagai obat antihipertensi adalah daun sirih Keraton (C. discolor). Daun sirih Keraton telah digunakan dalam pengobatan tradisional untuk berbagai kondisi, termasuk hipertensi, berkat kandungan senyawa bioaktif seperti flavonoid, alkaloid, dan saponin. Penelitian ini bertujuan untuk memberikan gambaran tentang tingkat keamanan ekstrak dan juga membantu dalam merancang protokol dosis yang lebih aman untuk uji klinis atau penggunaan dalam produk kesehatan. Penelitian ini menggunakan metode animal tasing dengan mengukur nilai LD50 menggunakan 30 tikus wistar jantan sebagai subjek penelitian yang terbagi dalam 5 kelompok perlakuan dengan dosis 500 mg/kgBB, 2000 mg/kgBB dan 5000 mg/kgBB. Hasil dari penelitian ini menunjukan bahwa ekstrak daun sirih keraton hingga dosis tertinggi tidak menunjukan gejala toksisitas. Meskipun tidak terdapat tanda-tanda toksisitas pada hewan uji hingga dosis tertinggi hasil penelitian ini dapat dikatakan sebagai toksisitas semu, tetapi hasil ini tetap dapat dijadikan rujuan awal tentang keamanan ekstrak daun sirih keraton ini. Sehingga masih diperlukan penelitian lanjutan untuk menentukan nilai LD50 yang sebenarnya.
THE ROLE OF TRIBULUS TERRESTRIS ON MALE INFERTILITY BASED ON CLINICAL TRIALS PERSPECTIVE: A NARRATIVE REVIEW Dona, Suzana; Kintoko, Kintoko; Mochammad Saiful, Bachri
Pharmacoscript Vol. 8 No. 2 (2025): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v8i2.2171

Abstract

Tribulus terrestris is a widely recognized herb with potential applications in healthcare. Male factor infertility, often stemming from testicular disorders, is frequently linked to inadequate sperm quantity and quality. While botanical products, including herbal medicines, have shown both positive and negative effects on male fertility and testicular function in the literature, this narrative review specifically aimed to identify clinical trials investigating the potential benefits of Tribulus terrestris in reducing male infertility and enhancing semen and hormonal parameters. A literature review methodology was employed, utilizing Scopus, PubMed, and Cochrane databases to gather full-text accessible published works from 2013 to 2022. Initially, 28 studies were identified; 24 were excluded, leaving three for full-text evaluation. Ultimately, three articles met the inclusion criteria and were included in this review. Based on the reviewed articles, Tribulus terrestris extract appears to influence the quantity and quality of spermatozoa, as well as reproductive hormone levels. Two articles reported a significant increase in sperm parameters and hormone levels. However, one article indicated no meaningful correlation between Tribulus terrestris use and an increase in testosterone levels. Further data are needed to definitively determine the efficacy of Tribulus terrestris as an infertility treatment.
Potential Secondary Metabolites in Guava (Psidium guajava) Assisted by Radar Chart Analysis (RCA) and Area Under Curve (AUC) Cendekiawan, Khrisna Agung; Kintoko, Kintoko; Yuliani, Sapto; Anggraeni, Linda Suci
MAGNA MEDIKA Berkala Ilmiah Kedokteran dan Kesehatan Vol 12, No 2 (2025): AUGUST
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.12.2.2025.196-207

Abstract

Background:  Diarrhea is a common health problem worldwide, with causes ranging from microbial infections to gastrointestinal disorders. Conventional diarrhea treatments usually involve synthetic drugs, but medicinal plant-based therapies, such as those containing secondary metabolite compounds in guava leaves, show promising potential. In this systematic review, we aimed to identify potential metabolite compounds.Objective: In this systematic review, we aim to identify potential secondary metabolite compounds in medicinal plants with antidiarrheal effects and explore the biological mechanisms of action involved.Methods: Using a literature review, relevant articles were analyzed from reputable scientific databases.Results: The results of the review indicate that compounds such as flavonoids, polyphenols, tannins, and saponins in guava leaves possess antidiarrheal potential, contributing to the regulation of intestinal motility, inhibition of inflammation, and alteration of the gut microbiota composition.Conclusion: The results of this study indicate that medicinal plants and their secondary metabolites can be a promising alternative for safer and more efficient antidiarrheal therapy.
Antioxidant Activity and Lipid Content of Aurantiochytrium sp. from Raja Ampat and Kepulauan Seribu Witasari, Hardi Astuti; Kintoko, Kintoko; Mahfudh, Nurkhasanah; Suhendra, Suhendra; Rangkuti, Ahmad Faizal; Ilmia, Nisrien; Santoso, Blegoh Iwan; Hutari, Andri
Squalen, Buletin Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 20, No 2 (2025): August 2025
Publisher : :Agency for Marine and Fisheries Research and Human Resources, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/squalen.1015

Abstract

Raja Ampat (Southwest Papua Province) and Kepulauan Seribu (Jakarta Raya Province) are part of Indonesia#39;s territory, which includes the mangrove forest area. This habitat supports a diverse array of animals, plants, and microalgae, including Aurantiochytrium sp. It has antioxidant activity related to lipid content. This study aims to identify the lipid content and the antioxidant effects of the microalgae Aurantiochytrium sp.’s extract isolated from the mangrove forest areas of Raja Ampat and Kepulauan Seribu. The extraction process was conducted using the Folch method, which involves a 2:1 (v/v) chloroform-methanol solvent ratio. The microalgae Aurantiochytrium sp. extract of Raja Ampat (MAERA) and microalgae Aurantiochytrium sp. extract of Kepulauan Seribu (MAEKS) were analyzed using GC-MS, antioxidant potential tested in silico by target proteins (5ZLG, 2A1X, 3VLN, and 1EEM) using Autodock Tools, and in vitro by DPPH and ABTS radicals and the carotenoid bleaching method. The results showed that total squalene and fatty acids in MAERA and MAEKS were at different levels. Squalene as a ligand had the lowest binding energy (-9.4, -6.6, -7.7, and -6.5) compared to the native ligand (-5.6, -4.4, -5.2, and -5.2) and ascorbic acid (-5.6, -4.8, -5.3, and -4.9) by in silico antioxidant activity. The in vitro antioxidant activities by DPPH, ABTS, and ß-caroteen bleaching were 103.00 ± 3.75, 216.39 ± 367, 214.62 ± 7,07 (MAERA); and 131.85 ± 23.48, 225.50 ± 3.36, 251.69 ± 5.39 (MAEKS) were not significantly different (pgt;0.05) by all methods. These findings showed that the Aurantiochytrium sp. strains Raja Ampat and Kepulauan Seribu contained diverse levels of fatty acids and squalene. In the in silico study, squalene was evaluated and in vitro, the MAERA and MAEKS extracts showed moderate antioxidant activity.
Pemberdayaan Perempuan Melalui Kelompok Wanita Tani Sunanti, Titis; Aviory, Koryna; Kintoko, Kintoko; Nuryani, Eva; Gunawan, Gunawan; Widyaningsih, Nina
Journal Of Human And Education (JAHE) Vol. 4 No. 1 (2024): Journal Of Human And Education (JAHE)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jh.v4i1.629

Abstract

Kelompok tani di dusun Ngentak dianggap mampu berperan penting dalam kehidupan keluarga dan bermasyarakat. Pendampingan pada kelompok ini sangat diperlukan agar dapat memberikan pengetahuan dan menjaga motivasi kelompok untuk meningkatkan kapasitas usaha. Tujuan kegiatan ini adalah meningkatkan peran kelompok wanita tani untuk mendorong para wanita tani mengelola sebuah organisasi dan meningkatkan kapasitas usaha dalam pertanian. Kegiatan ini sebagai sarana untuk belajar dan menyelesaikan permasalahan secara bersama-sama. Harapannya, kelompok ini dapat berkembang dan bertanggung jawab terhadap segala aktivitas sehingga dapat memberikan manfaat bagi para anggota dan lingkungan sekitar. Pendekatan yang digunakan dalam kegiatan ini adalah PRA (Parcitipatory Rural Appraisal). Pendekatan ini melibatkan seluruh anggota kelompok wanita tani untuk memahami masalah dan meningkatkan partisipasi anggota kelompok untuk menyelesaikan masalah mereka sendiri. Berdasarkan angket penilaian kebermanfaatan kegiatan menunjukkan bahwa kegiatan pengabdian ini sangat bermanfaat bagi anggota kelompok sasaran. Kegiatan pengabdian ini diawali dengan kegiatan peningkatan kapastitas kelompok, kemudian pelatihan budidaya tanaman hortikultur, dan pelatihan pembuatan likat kuning serta pendampingan kelompok usaha.
Potential Applications and Active Substances of Lavender Essential Oil as An Anti-Hypertension: Narrative Literature Review Setyawan, Aris; Kintoko, Kintoko
Indonesian Journal of Global Health Research Vol 6 No 4 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i4.3518

Abstract

Hypertension is one of the Cardiovascular Diseases (CVD) which is the highest cause of death, and current treatment has many side effects that can be life-threatening, so researchers are interested in providing safe treatment solutions. One of them is traditional medicine such as aromatherapy. Therefore, it is necessary to carry out narrative research in the literature reviewing the effectiveness of lavender aroma therapy in reducing blood pressure in hypertensive patients. This research uses a Narrative Review study approach which focuses on evaluating several previous research results related to the topic. Based on data used by Google Scholar, Pubmed, and Spinger between 2019 and 2024. A total of 1,394 articles were found in the initial search stage, after filtering based on title, keywords and abstract this was reduced to 10 articles. And finally only 4 articles were selected that fit the criteria. There were 2 types of lavender aromatherapy applications, namely topical and inhalation. As well as two anti-hypertension active substances, namely linalool and linalool acetate. Lavender aromatherapy is effective in lowering blood pressure in hypertensive patients. The mechanism of reduction can be explained by the active anti-hypertensive substance (linalool & linalool acetate) and its application (inhalation & topical). However, further research with better designs is still needed.
Co-Authors Akrom, Akrom Alfarisyi, Muhammad Iqbal Ananda, Aghnia Nabila Anggraeni, Linda Suci Ari Satia Nugraha Aris Setyawan Ariyanti, Lusi Mardika Astuti, Andarweni Atmarani, Rizki Essa aviory, koryna Ayu Shabrina Billy Harnaldo Putra, Dini Fatmi, Botutihe, Lisa Agustina Cahayani, Devita Mika Dani Kusuma Desmayanti, Astri Dhian Arista Istikomah Dian Aprilia, Dian Dona, Suzana Dwi Utami Eka Siswanto Syamsul Epi Taufik Faisal Nur Arib Fajar Fajar Farid , Muhammad Ferani Mulianingsih Gunawan Gunawan Gunawan, Adhi Gusriyani, Sri Gustinanda, Rizky Hadi Siswanto, Deny Hardi Astuti Witasari Hari Susanti Harry Ade Saputra Hasana, Siti Nur Hidayati, Eka Hutari, Andri Iis Wahyuningsih Ilmia, Nisrien Indahsari, Kharisma Safitri Nur Jana, Padrul Khrisna Agung Cendekiawan Khusnul, Latifah Kusumo, Djati Wulan Lestariningrum, Wahyu Titis M. Yogi Riyantama Isjoni Maghfirah, Yolanda Sajjida Makati, Annisa Camellia Mehta, Kunal Meki Pranata Mochammad Saiful, Bachri Muhammad Iqbal Birsyada Muldiyana, Tya Mustofa Ahda Mutti, Annisa Aulia Nanik Sulistyani Nina Widyaningsih, Nina Ningrum, Lailatul Fitria Nining Sugihartini Novitasari, Putri Rachma Nur Arib, Faisal Nurkhasanah Mahfudh Nurlita, Tasya Nuryani, Eva Oktavia, Lisa Pamungkas, Megita Dwi Poerwahyuningrum, Neny Pulhehe, Hasni Rangkuti, Ahmad Faizal Ranti, Imaniar Rejeki, Marsudi Endang Sri Restu Ayu Mumpuni, Restu Ayu Ridho, Anisa Rifka Rifki Febriansah Rohma, Siti Rohmah, Lely Arbiati Nur Rukaya, Benazir Evita Sa’adah, Hayatus Safira, Rizka Santoso, Blegoh Iwan Sapto Yuliani Saputri, Ginanjar Zukhruf Septian Aji Permana Septiana Wijayanti Setianingrum, Ervina Setiyawati, Fitri Indah Shary, Aprilya Kumala Siswanto, Deny Hadi Sri Budiarti, Nur Idha Suhendra Suhendra Sulistyani , Nanik Sunanti, Titis Supomo Supomo Suryaningsih, Andri Susetyawati, Endang Susetyawati, MM Endang Susetyawati, MM. Endang Susetyowati, MM Endang Tri Puspita Yuliana Urmatul Waznah Utami, Febri Via Yustitia Wahyu Widyaningsih Wahyuni, Dina Wardhani, Firdha Aprillia Warniasih, Kristina Widyaningrum, Rachmawati Wuryandari, Tutik Wuryandari, Tutik Yanti, Asti Afrida Yuli Nurullaili Efendi, Yuli Nurullaili Yulia Yesti, Yulia Yulianto Yulianto Yuni Suprapto, Yuni