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All Journal MNJ (Malang Neurology Journal) The Indonesian Biomedical Journal Jurnal Biologi Tropis Jurnal Ilmu Kedokteran dan Kesehatan Medika Kartika : Jurnal Kedokteran dan Kesehatan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia UMI Medical Journal Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Jurnal Abdi Insani Community Development Journal: Jurnal Pengabdian Masyarakat AKSONA Jurnal Kesehatan Qamarul Huda
Ilsa Hunaifi, Ilsa
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Potential of Marine Algae as Peripheral Neuropathy Therapy: An Article Review Widad, Najwa; Paerdoe, Lalu Dane Pemban; Qindi, Ahmad Sa’bi Al; Yulianti, Arwinda Febri; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9412

Abstract

Peripheral neuropathy is a peripheral nerve disorders involving sensory, motor, or mixed nerves. First-line therapies for peripheral neuropathy, such as analgesics and SSRIs, often yield suboptimal therapeutic responses, have side effects, and provide inadequate disease control. Therefore, there is a need for adjuvant therapy utilizing bioactive compounds from natural sources, one of which is marine algae. Marine algae contain various compounds that have the potential to serve as safe and effective alternative adjuvant therapies for peripheral neuropathy. The literature used was collected from the PubMed, ScienceDirect, and Google Scholar databases with restrictions: publication years from 2015 to 2025 and in either Indonesian or English. The review indicated that several compounds found in marine algae, such as florotanins, terpenoids, polysaccharides, peptide proteins, essential amino acids, and omega-3 fatty acids, exhibited biological activities such as antioxidant, anti-inflammatory, and neuroprotective effects. These compounds showed potential as alternative adjuvant therapies for peripheral neuropathy. In conclusion, the compounds in marine algae demonstrated various biological activities, suggesting their potential for development as alternative adjuvant therapies for peripheral neuropathy. Further research is needed to test their safety and effectiveness before being applied in clinical practice.
PELATIHAN DETEKSI DINI NEUROPATI AKIBAT KEMOTERAPI Hunaifi, Ilsa; Primayanti, Ika; Sapta Wardhani, Indah; Briliansy, Briliansy; Anggoro, Joko; Setyawati, Indri; Fesmia, Herodya Lajunee; Ismiana, Baiq Holisatul; Wiracakra, I Gusti Lanang Krisna; Gea, Endah Irnanda Ulfa; Jacob, Lusye Diana; Putri, Siti Noururrifqiyati Juna; Wardi, Bq. Prita Riantiani; Suryani, ⁠Dini; Andiyani, Dinda Zahra Putri
Jurnal Abdi Insani Vol 12 No 9 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i9.2843

Abstract

Cancer is currently a disease that is experiencing significant growth. This has resulted in the number of chemotherapy administrations reaching 9.8 million to 15 million people and increasing by 53%. One of the side effects that can be caused is peripheral nerve disorders called Chemotherapy-Induced Peripheral Neuropathy (CIPN). In connection with the increasing number of cancer patients undergoing chemotherapy and the severe impact on peripheral nerves due to chemotherapy, early detection is very important to prevent severe complications. This training aims to improve the knowledge and skills of medical personnel in the early detection of chemotherapy-induced neuropathy in order to improve the quality of life of patients and reduce complications and disabilities due to neuropathy. This training was carried out in collaboration with the West Nusa Tenggara Province General Hospital and was attended by 62 nurses. The series of training activities included delivering materials and direct practice to patients. Evaluation of participant knowledge was through a pre-test using the Kahoot application and a post-test using the Plataran Sehat application with a pre-test completion time of 5 minutes. The average pre-test score was 59.35, while the average post-test score was 79.35. The simulation sessions are conducted directly with patients using a neuropathy screening questionnaire, accompanied by a physician. The presentation of the material and the simulation sessions are highly beneficial in neuropathy screening, allowing early detection of neuropathy symptoms and prompt treatment.
Edukasi tentang Penyakit Myastenia Gravis pada Pengunjung Poliklinik Neurologi Rumah Sakit Universitas Mataram Harahap, Herpan Syafii; Hunaifi, Ilsa; Sahidu, Muhammad Ghalvan; Indrayana, Yanna; Ni Nyoman Ayu, Susilawati; Lestari, Diayanti Tenti; Zubaidi, Fitriannisa Faradina; Nurhidayati, Nurhidayati; Saputri, Legis Ocktaviana
Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Vol. 4 No. (1) (2022)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Myasthenia gravis is one of the most common autoimmune diseases at the neuromuscular junction. Although this disease is rare, the incidence of this disease is believed to have increased in the last seven decades. This community service activity aims to provide education to the public regarding myasthenia gravis. This community service activity was carried out in the form of counseling at the Neurology Polyclinic of UNRAM Hospital on Friday, January 20 2023. All participants were asked to take part in all counseling activities which consisted of pre-test activities, delivery of material on the topic of myasthenia gravis, and post-test. The enthusiasm of the participants in this activity was presented in the form of photo documentation. Statistical analysis using paired t-test was carried out to analyze the difference between the pre-test and post-test mean values ​​and the results were considered significant if a p value <0.05 was obtained. As many as 23 participants who attended the Neurology Polyclinic at UNRAM Hospital enthusiastically participated in the whole series of activities. The average participant post-test score was significantly higher than the pre-test means score (p = 0.025). This activity was able to increase the participants' knowledge about myasthenia gravis.
Penyuluhan mengenai Gangguan Kognitif Pasca Stroke di Poliklinik Neurologi Rumah Sakit Universitas Mataram Harahap, Herpan Syafii; Hunaifi, Ilsa; Sahidu, Muhammad Ghalvan; Indrayana, Yanna; Zubaidi, Fitriannisa Faradina; Andi, Silmi Chairan; Nurhayati, Putri; Lasmi, Anjely Doni; Miraditi, Ni Komang; Rusdi, Yudika Ilhami; Annafi, Muhammad Ibnu; Faizah, Lillah
Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Vol. 5 No. 1 (2023)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmsi.v5i1.205

Abstract

Cognitive impairment is one of the important complications of stroke with a high prevalence. If not detected and managed properly, this cognitive disorder can worsen into post-stroke severe cognitive impairment (vascular dementia) with social and economic impacts on the family. This community service activity aims to increase public understanding of the importance of recognizing memory loss in stroke patients. This activity is carried out in the form of counseling at the Neurology Polyclinic at UNRAM Hospital once a week for a period of 3 weeks involving visitors to the Neurology Polyclinic at UNRAM Hospital, both outpatients and their caregivers. The participants were asked to take part in a whole series of activities which included pre-test, counseling, discussion, and post-test. The number of participants who took part in this counseling activity were 36 subjects. The participants' relatively high interest in participating in this activity can be seen from the documentation of the entire series of activities and the significant increase in the post-test mean score compared to the pre-test average score at the statistical analysis stage (p <0.05). This activity showed high effectiveness in increasing participants' understanding of memory loss in stroke patients.
HUBUNGAN KADAR NEUTROFIL DENGAN KEJADIAN SINDROM FRAILTY PADA LANJUT USIA DI PANTI SOSIAL LANJUT USIA MANDALIKA MATARAM Rifansha, Muhammad Ghifari; Hunaifi, Ilsa; Primayanti, Ika
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 8 No 3 (2025): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

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Abstract

Lanjut usia (lansia) adalah kondisi seseorang mencapai usia enam puluh tahun atau lebih. Proses penuaan menjadi salah satu faktor risiko berkurangnya fungsi tubuh atau berkurangnya kemampuan fisiologis yang menyebabkan lansia menjadi kelompok yang rentan mengalami penurunan kemampuan fisiologis, yang dapat mengarah pada kejadian frailty. Frailty adalah suatu kondisi medis yang ditandai dengan penurunan kekuatan, daya tahan, dan fungsi fisik secara keseluruhan, yang membuat individu mengalami penurunan kemampuan untuk menjalani aktivitas sehari-hari, meningkatnya risiko jatuh, rawat inap, dan kematian. Peningkatan jumlah neutrofil bersamaan dengan gangguan migrasi neutrofil terkait usia, dapat menyebabkan kerusakan jaringan dan inflamasi sekunder yang mendukung gambaran inflamasi pada frailty. Saat ini penelitian hubungan antara kadar neutrofil dengan frailty masih terbatas sehingga diperlukan studi mengenai hubungan antara kadar neutrofil dengan frailty. Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional di Panti Sosial Lanjut Usia Mandalika Kota Mataram. Adapun jumlah responden dalam penelitian ini sebesar 48 orang dan karakteristik responden disajikan dalam distribusi dan frekuensi. Analisis data menggunakan uji Kolmogorov Smirnov Z Test. Dari total 48 responden, terdapat 36 orang (75%) memiliki kadar neutrofil normal dan 12 orang (25%) kadar neutrofil abnormal. Jumlah responden dengan kategori sehat berjumlah 19 orang (39,6%), dengan kategori pre-frailty berjumlah 21 orang (43,8%) dan 8 orang (16,7%) dengan kategori frailty. Hasil uji Kolmogorov Smirnov Z Test. menunjukkan tidak terdapat hubungan antara kadar neutrofil dengan kejadian sindrom frailty (p = 0,057). Maka dapat disimpulkan bahwa tidak terdapat hubungan antara kadar neutrofil dan kejadian frailty pada lansia. Kata Kunci : frailty, lanjut usia, neutrofil DOI : 10.35990/mk.v8n3.p299-308
Krisis Miastenik: Literature Review Atmaja, I Made Brama; Rahmat, Dwi; Hunaifi, Ilsa
Jurnal Kesehatan Qamarul Huda Vol. 10 No. 2 (2022): Desember 2022
Publisher : Universitas Qamarul Huda Badaruddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37824/jkqh.v10i2.2022.401

Abstract

Krisis Miastenik merupakan komplikasi dari penyakit Miastenia Gravis (MG) yang ditandai dengan terjadinya perburukan kelemahan otot yang signifikan sehingga menyebabkan kegagalan respiratori dan membutuhkan intubasi dan ventilasi mekanik. Tujuan dari penulisan tinjauan pustaka ini adalah untuk membahas secara komprehensif mengenai krisis miastenik dan penatalaksanaan yang tepat pada pasien miastenia gravis dengan komplikasi krisis miastenik. Metode penulisan tinjauan pustaka ini menggunakan metode literature review. Penelusuran tinjauan pustaka menggunakan Pubmed, Researchgate, dan Google Scholar. Sebanyak 20 artikel masuk ke dalam tinjauan pustaka. Tinjauan pustaka ini membahas definisi, epidemiologi, manifestasi klinis, diagnosis, tatalaksana, kompliksai dan prognosis, serta perbedaan antara Krisis Miastenik dan Krisis Kolinergik. Diharapkan dari tinjauan pustaka ini dapat memberikan pemahaman lebih lanjut terkait Krisis Miastenik.
Effect of MLC901 on Red Cell Distribution Width (RDW) in Acute Ischemic Stroke: Literature Review Ilham, M. Arya Rifqi; Hunaifi, Ilsa; Dirja, Bayu Tirta
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.6833

Abstract

Acute ischemic stroke is an acute episode of neurological dysfunction caused by focal infarction or damage that persists for ≥24 hours in the brain, spine, and retinal. Stroke is the second highest cause of death worldwide. The total prevalence of stroke continues to increase in the world and in Indonesia. However, stroke treatment is still less effective, so adjuvant therapy needs to be developed; one of them is MLC901. However, this therapy still needs to be studied further regarding its effect on acute ischemic stroke and the biomarkers used as the prognostic factors, such as red cell distribution width (RDW). This paper aims to determine the effect of MLC901 therapy on RDW values in acute ischemic stroke by analyzing various previous studies from different databases as a reference. Increased RDW values are associated with poor outcomes of acute ischemic stroke. MLC901 was shown to have neuroprotective and neurorestorative abilities in neurons that are under stress due to ischemia. MLC901 also can reduce inflammatory responses, reduce oxidative stress, and increase erythropoietin (EPO) production. So, administration of adjuvant MLC901 therapy can reduce RDW values and improve neurological outcomes in acute ischemic stroke.
Current Therapies for Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Literature Review Wicaksono, Teguh Budi; Nugraha, Gede Rama Hardy; Maulida, Rizka Ayu; Kusumadewi, Rima Cahyati; Pratiwi, Rukmanggana Satya; Amaliya, Annisa Risqi; Sepestian, Ghina Shadrina Rienti; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7395

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease. The European Academy of Neurology recommends treatment using corticosteroids, immunoglobulin, plasma exchange, & other treatments as treatment options for chronic inflammatory demyelinating polyradiculoneuropathy. However, several studies in recent years have shown that there is potential in the treatment of chronic inflammatory demyelinating Polyradiculoneuropathy. The aim of this literature review is to provide the latest therapy for chronic inflammatory demyelinating polyradiculoneuropathy based on guidelines as well as other information therapy alternatives. The method used in this literature review uses searches in several databases. The results of several studies show the development of chronic inflammatory demyelinating polyradiculoneuropathy therapy both pharmacologically & non-pharmacologically. The development of therapy for chronic inflammatory demyelinating polyradiculoneuropathy, namely hematopoietic stem cells & spinal cord stimulation, shows potential as a therapeutic option for patients with chronic inflammatory demyelinating polyradiculoneuropathy.
Diagnosis and Management of Post Traumatic Epilepsy Ramzi, Ali; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7667

Abstract

Traumatic brain injury (TBI) is a leading cause of disability and death, particularly among children and young adults, and can result in serious complications such as post-traumatic epilepsy (PTE). PTE develops after TBI and is characterized by recurrent seizures without external triggers, with the risk influenced by the location and severity of the injury. Therefore, the authors raise this topic to help improve diagnostic acuity and highlight the importance of laboratory modalities in diagnosing PTE. The literature search was conducted using Google Scholar with the keywords "Post-Traumatic Epilepsy, Biomarkers, Management, Diagnosis." Based on the inclusion and exclusion criteria, 17 publications were identified as suitable for our literature review. Diagnostic tools such as CT scans, MRIs, and EEGs are essential for assessing risk. Although antiepileptic drugs (AEDs) can reduce early seizures, they are not effective for the long-term prevention of PTE. Long-term approaches, including lamotrigine, carbamazepine, and vagus nerve stimulation (VNS), may be beneficial, but further research is needed to optimize treatment.
Emergencies in The Maritime Field A Literatur Review Salsabila, Rika Kamila; Kamilah, Nilam Nurmilatun; Putri, Atina Rizki; Pramudia, Prananda Rizki; Rian Pramudya; Saraswati, Ni Wayan Citra Ayu; Amatullah, Tazkiyah Arafah; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 24 No. 2b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2b.7800

Abstract

Indonesia is the largest archipelagic country in the world, with extensive coastal and oceanic areas and a high diversity of marine biodiversity. The coastal regions of Indonesia serve as habitats for various types of marine animals that possess both beauty and potential dangers, particularly from marine animal stings. In addition to marine animal stings, decompression sickness also poses a serious emergency in the maritime context. The purpose of this article is to provide new insights into the importance of understanding and recognizing decompression syndrome, as well as the bites and stings caused by marine animals, as early indicators of emergencies in the maritime field. This understanding can enhance early detection, appropriate treatment, and awareness of complications arising from maritime emergencies. The article will focus on marine animals such as the blue-ringed octopus, sea urchins, pufferfish, lionfish, jellyfish, stingrays, and stonefish, which are associated with emergencies in the maritime field. Data sources were gathered through electronic searches on library databases including Google Scholar, ProQuest, MDPI, and PubMed to find articles discussing "emergencies in the maritime field.".
Co-Authors Adhima, Daffa Aulia Faza Agistany, Nur Feby Febiana Alamanda, Baiq Irzana Putri Amalia, Azka Amaliya, Annisa Risqi Amanullah, Mohammad Sany Rosafi Amatullah, Tazkiyah Arafah Ammar Rusydi, Muhammad Ananta, Muhammad Naufal Farras Andi Alfian Zainuddin Andi Asadul Islam Andi Kurnia Bintang, Andi Kurnia andi, Silmi chairan Andiyani, Dinda Zahra Putri Angelina, Varelia Anggoro, Joko Annafi, Muhammad Ibnu Annisa, Wardha Novia Aryasta, Ida Bagus Putra Bayu Atari, Sicillia Putri Atmaja, I Made Brama Aulia, Siti Zahroni Bharata, Irsyadina Hasana Binti Amir, Nurul Aulia Briliansy, Briliansy Dewi Suryani Dewi, Putri Krishna Kumara Diatmika, I Putu Dini Suryani, Dini Dirja, Bayu Tirta Dwi Febrian, Haldy Faizah, Lillah Farobbi, Muhammad Iqbal Fauzi, Yanuar Rahmat Febianisa, Tabitha Afifah Fesmia, Herodya Lajunee Fitriantoro, Santo Fitroningtyas, Elvika Aulia Gea, Endah Irnanda Ulfa Ginuluh, Gintis Dhimar Hadinata, Lalu Gde Gilang Alid Hasin, Raisya Hatta, Mohammad Helmiana, Putri Fatimah Herpan Syafii Harahap Hidayati, Eriska Humam, Anang Muh Naufal Ilham, M. Arya Rifqi Ilmiah, Janiya Abdila Indrayana, Yanna Ismiana, Baiq Holisatul Jacob, Lusye Diana Justitia, Ica Kamila, Alya Syafa Kamilah, Nilam Nurmilatun Khairifathiyyah, Khairifathiyyah Khaula Karima kholida, Baiq Hilya Krisna , I Gusti Lanang Kurniawan, Theophany Margareta Kusumadewi, Rima Cahyati Kuta, Putu Cicilia Rarasati Landapa, Raditya Rachman Lasmi, Anjely Doni Lazuardi Arsy, Lazuardi Lestari, Diayanti Tenti Maharani, Baiq Nadya Putri Maulida, Rizka Ayu Miraditi, Ni Komang Moestafa, Rizka Febriya Mutiara Syifa, R.R. Ditya Ni Nyoman Ayu, Susilawati Nisa Isneni Hanifa Nugraha, Gede Rama Hardy Nuralyza, Imasayu Nurhayati, Putri Nurhidayati Nurhidayati Ocktaviana Saputri, Legis Padma Puspita, Ni Made Sri Paerdoe, Lalu Dane Pemban Pambudi, Balqis Prudena Kurnia Paradhini, Tri Sastra Paradiesta, Andi Frieskha Naurah Paulus Sugianto, Paulus Pramudia, Prananda Rizki Pratiwi, Rukmanggana Satya Prawira, I Nyoman Dio Yudha Primayanti , Ika Primayanti, Ika Puspasari Mahadewi, Ni Made Putri, Atina Rizki Putri, Siti Noururrifqiyati Juna Qindi, Ahmad Sa’bi Al Rahmadini, Nasyada Fadhila Rahmat, Dwi Ramzi, Ali Rian Pramudya Riantiani, Baiq Prita Rifansha, Muhammad Ghifari Rusdi, Yudika Ilhami Safitri, Nasywa Aulia Sahidu, Muhammad Ghalvan Salsabila, Rika Kamila Sapta Wardhani, Indah Saraswati, Ni Wayan Citra Ayu Sepestian, Ghina Shadrina Rienti Setyawati, Indri Setyo Pambudi , Arif Shafitri, Shira Shalsabina Sugiono, Muhammad Rafly Adrian Suryani, ⁠Dini Tammasse, Jumraini Teguh Budi Wicaksono Ulfa Gea, Indah Ernanda Untari, Lania Pradiva Wahid, Isra' Wahyu Maharani, Amelia Wardi, Baiq Prita Riantiani Wardi, Bq. Prita Riantiani Widad, Najwa Wiracakra, I Gusti Lanang Krisna Yulianti, Arwinda Febri Zubaidi, Fitriannisa Faradina