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All Journal MNJ (Malang Neurology Journal) Jurnal Biologi Tropis Jurnal Ilmu Kedokteran dan Kesehatan Medika Kartika : Jurnal Kedokteran dan Kesehatan UMI Medical Journal Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Jurnal Abdi Insani AKSONA Jurnal Kesehatan Qamarul Huda Folia Medica Indonesiana
Ilsa Hunaifi, Ilsa
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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EDUKASI GANGGUAN SARAF TEPI AKIBAT OBAT KEMOTERAPI PADA PASIEN POLI ONKOLOGI RUMAH SAKIT UMUM DAERAH (RSUD) PROVINSI NUSA TENGGARA BARAT Hunaifi, Ilsa; Briliansy, Briliansy; Anggoro, Joko; Bharata, Irsyadina Hasana; Adhima, Daffa Aulia Faza; Karima, Khaula; Kuta, Putu Cicilia Rarasati; Fitroningtyas, Elvika Aulia; Hidayati, Eriska; Moestafa, Rizka Febriya; Maharani, Baiq Nadya Putri
Jurnal Abdi Insani Vol 11 No 2 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i2.1522

Abstract

Peripheral neuropathy is a disorder of peripheral nerve fibres secondary to various pathological processes such as diabetes mellitus, vitamin deficiencies or drugs such as chemotherapy regimen. Clinical symptoms include motor, sensory and autonomic disorders. Cancer patients undergoing chemotherapy are susceptible to experiencing symptoms of peripheral neuropathy caused by anatomical changes (such as distal axonal degeneration) or physiological changes. So, the education of regarding peripheral neuropathy is needed in patients with chemotherapy. This community service activity was conducted in the Oncology Building at West Nusa Tenggara Province General Hospital. Implementing activities regarding education on peripheral nerve disorders due to chemotherapy drugs is carried out by providing pretests, educational materials, post-tests and discussions. In the pretest activity, many participants were still unaware of peripheral nerve disorders due to chemoteraphy side effects. In the post-test, the knowledge score was above average (100%) regarding peripheral nerve disorders due to chemoterapy side effects. This shows an increase in the understanding of the side effects of chemotherapy in oncology outpatients clinic at West Nusa Tenggara Province General Hospital
Impact of Coma Duration on Functional Outcomes After Septic Encephalopathy: A Literature Review Shafitri, Shira Shalsabina; Sugiono, Muhammad Rafly Adrian; Paradiesta, Andi Frieskha Naurah; Aulia, Siti Zahroni; Ilmiah, Janiya Abdila; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10516

Abstract

Sepsis-associated encephalopathy (SAE) is a neurological complication often found on sepsis patients and is associated with high morbidity and mortality rates. It arises from systemic inflammation, blood-brain barrier disruption, microglial and astrocytic activation, and oxidative stress which collectively contribute to neuronal injury and long-term cognitive impairment. This literature review aims to analyze the impact of coma duration on functional outcomes at discharge and long-term survival among patients with SAE. Literatures were searched through PubMed, ScienceDirect, and Google Scholar with a 10-year publication limit and selected based on topic relevance, study design, and data completeness and were analyzed using a narrative synthesis approach. Findings indicate that prolonged coma duration is strongly associated with poor neurological recovery, increased risk of disability, and early mortality. Conversely, early recovery of consciousness tends to correlate with better short-term functional outcomes. However, among survivors discharged from intensive care, coma duration doesn’t consistently predict long-term survival, although cognitive and quality of life impairments often persist. In conclusion, coma duration serves as an important prognostic factor in SAE, but it should be interpreted alongside other factors such as age, comorbidity, and the severity of sepsis itself. The scientific implications highlight the need for , infection control, and rehabilitative strategies to shorten periods of altered consciousness and improve neurological outcomes in the long term.
Cerebral Stroke Secondary to Decompression Ilness (DCI): Pathophysiology, Clinical Presentation, Diagnosis, and Management Khairifathiyyah, Khairifathiyyah; Aryasta, Ida Bagus Putra Bayu; Prawira, I Nyoman Dio Yudha; Untari, Lania Pradiva; Pambudi, Balqis Prudena Kurnia; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10783

Abstract

Decompression illness (DCI) encompasses two major diving-related disorders: decompression sickness (DCS) and arterial gas embolism (AGE). Both conditions are characterized by the formation of gas bubbles that act as the primary mechanism of tissue injury, resulting in overlapping clinical manifestations and similar therapeutic approaches. This study aims to review the pathophysiology, clinical presentation, diagnosis, and management of DCI that presents with stroke-like neurological symptoms. The method used was a literature review approach based on current evidence from recent scientific publications. Findings show that DCS occurs when dissolved inert gases, such as nitrogen, become supersaturated during ascent and form bubbles within tissues and the venous circulation. AGE typically arises from pulmonary barotrauma, allowing trapped gas to enter the pulmonary veins and reach the arterial circulation, with the brain as the most vulnerable target organ. DCI is considered a medical emergency requiring definitive management with hyperbaric oxygen therapy (HBOT). Neurological manifestations of DCI often resemble conventional ischemic stroke but demonstrate distinct clinical and temporal patterns related to pressure changes. Therefore, in addition to recompression therapy, patients may require standard acute stroke management. Prognosis depends heavily on the promptness of diagnosis and treatment, as early intervention is critical to preventing permanent neurological injury.
THE EFFECT OF MLC901 ON RED CELL DISTRIBUTION WIDTH (RDW) AS A PREDICTOR OF ACUTE ISCHEMIC STROKE OUTCOME IN ACUTE ISCHEMIC STROKE MODEL IN RATS Ilham, Muhammad Arya Rifqi; Hunaifi, Ilsa; Dirja, Bayu Tirta
Folia Medica Indonesiana Vol. 61, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Stroke is the second leading cause of death globally, with ischemic stroke being the most prevalent type. Thrombolysis is the standard treatment for ischemic stroke; however, the rate of thrombolysis administration remains low. Therefore, neuroprotective therapies such as MLC901 are considered promising alternatives. The role of MLC901 in influencing red cell distribution width (RDW) during pathological ischemic stroke remains unclear. Hence, research on the effect of MLC901 on RDW is warranted. Male rats (n = 15) were divided into three groups: (1) acute ischemic stroke treated with MLC901 at a dose of 43.2 mg, (2) acute ischemic stroke treated with MLC901 at 21.6 mg, and (3) acute ischemic stroke treated with CMC-Na (positive control). Stroke was induced using the unilateral carotid artery occlusion (UCAO) method. RDW was measured before stroke induction and at 24 hours, 72 hours, and day 14. Neurological deficits were assessed using the foot fault score, and infarct volume was measured using ImageJ software. Following stroke induction, the positive control group had the highest mean RDW value, followed by the 21.6 mg and 43.2 mg MLC901 groups. However, there were no significant differences between the groups (p > 0.05). The positive control group exhibited greater neurological deficits compared to the MLC901 groups, with significant differences observed on days 7 and 14 (p < 0.05). Additionally, the positive control group had a significantly larger infarct volume than the MLC901 groups (p < 0.05). In conclusion, MLC901 did not affect RDW values but significantly reduced neurological deficits and infarct volume.
Co-Authors Adhima, Daffa Aulia Faza Agistany, Nur Feby Febiana Amalia, Azka Amaliya, Annisa Risqi Amatullah, Tazkiyah Arafah Ammar Rusydi, Muhammad andi, Silmi chairan Andiyani, Dinda Zahra Putri Anggoro, Joko Annafi, Muhammad Ibnu Annisa, Wardha Novia Aryasta, Ida Bagus Putra Bayu Atari, Sicillia Putri Atmaja, I Made Brama Aulia, Siti Zahroni Bharata, Irsyadina Hasana Binti Amir, Nurul Aulia Briliansy, Briliansy Dewi, Putri Krishna Kumara Dini Suryani, Dini Dirja, Bayu Tirta Dwi Febrian, Haldy Faizah, Lillah Fauzi, Yanuar Rahmat Febianisa, Tabitha Afifah Fesmia, Herodya Lajunee Fitriantoro, Santo Fitroningtyas, Elvika Aulia Gea, Endah Irnanda Ulfa Ginuluh, Gintis Dhimar Hadinata, Lalu Gde Gilang Alid Helmiana, Putri Fatimah Herpan Syafii Harahap Hidayati, Eriska Humam, Anang Muh Naufal Ilham, M. Arya Rifqi Ilham, Muhammad Arya Rifqi Ilmiah, Janiya Abdila Indrayana, Yanna Ismiana, Baiq Holisatul Jacob, Lusye Diana Justitia, Ica Kamila, Alya Syafa Kamilah, Nilam Nurmilatun Khairifathiyyah, Khairifathiyyah Khaula Karima kholida, Baiq Hilya Krisna , I Gusti Lanang Kurniawan, Theophany Margareta Kusumadewi, Rima Cahyati Kuta, Putu Cicilia Rarasati Landapa, Raditya Rachman Lasmi, Anjely Doni Lazuardi Arsy, Lazuardi Lestari, Diayanti Tenti Maharani, Baiq Nadya Putri Maulida, Rizka Ayu Miraditi, Ni Komang Moestafa, Rizka Febriya Mutiara Syifa, R.R. Ditya Ni Nyoman Ayu, Susilawati Nugraha, Gede Rama Hardy Nurhayati, Putri Nurhidayati Nurhidayati Ocktaviana Saputri, Legis Padma Puspita, Ni Made Sri Paerdoe, Lalu Dane Pemban Pambudi, Balqis Prudena Kurnia Paradhini, Tri Sastra Paradiesta, Andi Frieskha Naurah Pramudia, Prananda Rizki Pratiwi, Rukmanggana Satya Prawira, I Nyoman Dio Yudha Primayanti , Ika Primayanti, Ika Puspasari Mahadewi, Ni Made Putri, Atina Rizki Putri, Siti Noururrifqiyati Juna Qindi, Ahmad Sa’bi Al Rahmadini, Nasyada Fadhila Rahmat, Dwi Ramzi, Ali Rian Pramudya Riantiani, Baiq Prita Rifansha, Muhammad Ghifari Rusdi, Yudika Ilhami Safitri, Nasywa Aulia Sahidu, Muhammad Ghalvan Salsabila, Rika Kamila Sapta Wardhani, Indah Saraswati, Ni Wayan Citra Ayu Sepestian, Ghina Shadrina Rienti Setyawati, Indri Setyo Pambudi , Arif Shafitri, Shira Shalsabina Sugiono, Muhammad Rafly Adrian Suryani, ⁠Dini Teguh Budi Wicaksono Ulfa Gea, Indah Ernanda Untari, Lania Pradiva Wahyu Maharani, Amelia Wardi, Baiq Prita Riantiani Wardi, Bq. Prita Riantiani Widad, Najwa Wiracakra, I Gusti Lanang Krisna Yulianti, Arwinda Febri Zubaidi, Fitriannisa Faradina