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Pathophysiology of Rabies Encephalitis and Treatment of Rabies : A Literature Review Ginuluh, Gintis Dhimar; Kamila, Alya Syafa; Humam, Anang Muh Naufal; Helmiana, Putri Fatimah; Pratiwi, Rukmanggana Satya; Hunaifi, Ilsa; Arsy, Lazuardi
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7951

Abstract

Rabies is a zoonotic disease transmitted by the saliva of mammals infected with Rabies lyssavirus. Rabies is a lethal disease that is still a health problem in Indonesia. This article aims to review the clinical features, diagnosis, pathophysiology, and management of rabies. This research collects and analyzes literature related to rabies that was conducted through Google Scholar, Pubmed, and ScienceDirect. The review results show that rabies with clinical features, especially rabies encephalitis had poor outcomes. Rabies is a neurotropic virus that spreads through neurons and attack CNS causing rabies encephalitis. The management is categorized into pre-exposure treatment, post-exposure treatment, and palliative treatment. An understandable information regarding the mechanism of rabies encephalitis and rabies management is very important to minimize deaths caused by rabies.
Vaccine Administration Risk in Guillain-Barré Syndrome: A Systematic Review Febianisa, Tabitha Afifah; Hadinata, Lalu Gde Gilang Alid; Hunaifi, Ilsa; Amalia, Azka
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10361

Abstract

Guillain-Barré syndrome (GBS) is a disorder in which the body's immune system attacks the peripheral nervous system due to molecular mimicry, characterized by progressive muscle weakness from distal to proximal. This systematic review examines the relationship between vaccination and the risk of GBS. Epidemiological data indicate that the incidence of GBS after vaccination is very low. Although there is a link between vaccination and GBS in some cases, the risk remains smaller than the risk of GBS due to natural infection with the pathogen. This study emphasizes that the benefits of vaccination in preventing infection outweigh the risk of vaccination causing GBS. Guillain-Barré syndrome (GBS) is a disorder in which the body's immune system attacks the peripheral nervous system due to molecular mimicry, causing muscle weakness that progresses rapidly to paralysis. From this literature review, it can be concluded that the risk of GBS after vaccination is very low and is limited to certain vaccines. Furthermore, GBS cases occur more frequently after viral or bacterial infections than after vaccination, indicating that the benefits of vaccination in preventing infectious diseases far outweigh the risk of causing GBS.
EDUKASI GANGGUAN SARAF TEPI AKIBAT OBAT KEMOTERAPI PADA PASIEN POLI ONKOLOGI RUMAH SAKIT UMUM DAERAH (RSUD) PROVINSI NUSA TENGGARA BARAT Hunaifi, Ilsa; Briliansy, Briliansy; Anggoro, Joko; Bharata, Irsyadina Hasana; Adhima, Daffa Aulia Faza; Karima, Khaula; Kuta, Putu Cicilia Rarasati; Fitroningtyas, Elvika Aulia; Hidayati, Eriska; Moestafa, Rizka Febriya; Maharani, Baiq Nadya Putri
Jurnal Abdi Insani Vol 11 No 2 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i2.1522

Abstract

Peripheral neuropathy is a disorder of peripheral nerve fibres secondary to various pathological processes such as diabetes mellitus, vitamin deficiencies or drugs such as chemotherapy regimen. Clinical symptoms include motor, sensory and autonomic disorders. Cancer patients undergoing chemotherapy are susceptible to experiencing symptoms of peripheral neuropathy caused by anatomical changes (such as distal axonal degeneration) or physiological changes. So, the education of regarding peripheral neuropathy is needed in patients with chemotherapy. This community service activity was conducted in the Oncology Building at West Nusa Tenggara Province General Hospital. Implementing activities regarding education on peripheral nerve disorders due to chemotherapy drugs is carried out by providing pretests, educational materials, post-tests and discussions. In the pretest activity, many participants were still unaware of peripheral nerve disorders due to chemoteraphy side effects. In the post-test, the knowledge score was above average (100%) regarding peripheral nerve disorders due to chemoterapy side effects. This shows an increase in the understanding of the side effects of chemotherapy in oncology outpatients clinic at West Nusa Tenggara Province General Hospital
PENYULUHAN PEMANFAATAN TANAMAN KATANG-KATANG (IPOMOEA PES-CAPRAE) SEBAGAI ALTERNATIF PENGOBATAN TRADISIONAL DI MASYARAKAT DESA TAMAN AYU, GERUNG, LOMBOK BARAT Ananta, Muhammad Naufal Farras; Angelina, Varelia; Alamanda, Baiq Irzana Putri; Farobbi, Muhammad Iqbal; Nuralyza, Imasayu; Hunaifi, Ilsa; Hasin, Raisya; Suryani, Dewi; Hanifa, Nisa Isneni
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2025): Volume 6 No. 1 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i1.40706

Abstract

Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pemahaman masyarakat Desa Taman Ayu, Gerung, Lombok Barat, mengenai manfaat Ipomoea pes-caprae sebagai alternatif pengobatan tradisional. Metode kegiatan meliputi pretest, ceramah, sesi tanya jawab, pembagian leaflet, dan posttest, yang dilakukan secara langsung kepada 30 peserta. Penyampaian materi mencakup pengenalan tanaman, manfaat tradisionalnya, dan cara pengolahannya. Hasil kegiatan menunjukkan peningkatan pengetahuan dan keterampilan masyarakat dalam memanfaatkan tanaman ini untuk pengobatan, seperti mengatasi nyeri perut, kram, dan sengatan ubur-ubur. Diskusi interaktif juga memperkuat pemahaman peserta. Kesimpulan dari kegiatan ini adalah bahwa penyuluhan efektif dalam membangun kesadaran masyarakat tentang pemanfaatan sumber daya lokal untuk kesehatan holistik, mendukung pengelolaan lingkungan berkelanjutan, serta meningkatkan kapasitas mereka dalam pengolahan obat tradisional.
Impact of Coma Duration on Functional Outcomes After Septic Encephalopathy: A Literature Review Shafitri, Shira Shalsabina; Sugiono, Muhammad Rafly Adrian; Paradiesta, Andi Frieskha Naurah; Aulia, Siti Zahroni; Ilmiah, Janiya Abdila; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10516

Abstract

Sepsis-associated encephalopathy (SAE) is a neurological complication often found on sepsis patients and is associated with high morbidity and mortality rates. It arises from systemic inflammation, blood-brain barrier disruption, microglial and astrocytic activation, and oxidative stress which collectively contribute to neuronal injury and long-term cognitive impairment. This literature review aims to analyze the impact of coma duration on functional outcomes at discharge and long-term survival among patients with SAE. Literatures were searched through PubMed, ScienceDirect, and Google Scholar with a 10-year publication limit and selected based on topic relevance, study design, and data completeness and were analyzed using a narrative synthesis approach. Findings indicate that prolonged coma duration is strongly associated with poor neurological recovery, increased risk of disability, and early mortality. Conversely, early recovery of consciousness tends to correlate with better short-term functional outcomes. However, among survivors discharged from intensive care, coma duration doesn’t consistently predict long-term survival, although cognitive and quality of life impairments often persist. In conclusion, coma duration serves as an important prognostic factor in SAE, but it should be interpreted alongside other factors such as age, comorbidity, and the severity of sepsis itself. The scientific implications highlight the need for , infection control, and rehabilitative strategies to shorten periods of altered consciousness and improve neurological outcomes in the long term.
Cerebral Stroke Secondary to Decompression Ilness (DCI): Pathophysiology, Clinical Presentation, Diagnosis, and Management Khairifathiyyah, Khairifathiyyah; Aryasta, Ida Bagus Putra Bayu; Prawira, I Nyoman Dio Yudha; Untari, Lania Pradiva; Pambudi, Balqis Prudena Kurnia; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10783

Abstract

Decompression illness (DCI) encompasses two major diving-related disorders: decompression sickness (DCS) and arterial gas embolism (AGE). Both conditions are characterized by the formation of gas bubbles that act as the primary mechanism of tissue injury, resulting in overlapping clinical manifestations and similar therapeutic approaches. This study aims to review the pathophysiology, clinical presentation, diagnosis, and management of DCI that presents with stroke-like neurological symptoms. The method used was a literature review approach based on current evidence from recent scientific publications. Findings show that DCS occurs when dissolved inert gases, such as nitrogen, become supersaturated during ascent and form bubbles within tissues and the venous circulation. AGE typically arises from pulmonary barotrauma, allowing trapped gas to enter the pulmonary veins and reach the arterial circulation, with the brain as the most vulnerable target organ. DCI is considered a medical emergency requiring definitive management with hyperbaric oxygen therapy (HBOT). Neurological manifestations of DCI often resemble conventional ischemic stroke but demonstrate distinct clinical and temporal patterns related to pressure changes. Therefore, in addition to recompression therapy, patients may require standard acute stroke management. Prognosis depends heavily on the promptness of diagnosis and treatment, as early intervention is critical to preventing permanent neurological injury.
Co-Authors Adhima, Daffa Aulia Faza Agistany, Nur Feby Febiana Alamanda, Baiq Irzana Putri Amalia, Azka Amaliya, Annisa Risqi Amanullah, Mohammad Sany Rosafi Amatullah, Tazkiyah Arafah Ammar Rusydi, Muhammad Ananta, Muhammad Naufal Farras Andi Alfian Zainuddin Andi Asadul Islam Andi Kurnia Bintang, Andi Kurnia andi, Silmi chairan Andiyani, Dinda Zahra Putri Angelina, Varelia Anggoro, Joko Annafi, Muhammad Ibnu Annisa, Wardha Novia Aryasta, Ida Bagus Putra Bayu Atari, Sicillia Putri Atmaja, I Made Brama Aulia, Siti Zahroni Bharata, Irsyadina Hasana Binti Amir, Nurul Aulia Briliansy, Briliansy Dewi Suryani Dewi, Putri Krishna Kumara Diatmika, I Putu Dini Suryani, Dini Dirja, Bayu Tirta Dwi Febrian, Haldy Faizah, Lillah Farobbi, Muhammad Iqbal Fauzi, Yanuar Rahmat Febianisa, Tabitha Afifah Fesmia, Herodya Lajunee Fitriantoro, Santo Fitroningtyas, Elvika Aulia Gea, Endah Irnanda Ulfa Ginuluh, Gintis Dhimar Hadinata, Lalu Gde Gilang Alid Hasin, Raisya Hatta, Mohammad Helmiana, Putri Fatimah Herpan Syafii Harahap Hidayati, Eriska Humam, Anang Muh Naufal Ilham, M. Arya Rifqi Ilmiah, Janiya Abdila Indrayana, Yanna Ismiana, Baiq Holisatul Jacob, Lusye Diana Justitia, Ica Kamila, Alya Syafa Kamilah, Nilam Nurmilatun Khairifathiyyah, Khairifathiyyah Khaula Karima kholida, Baiq Hilya Krisna , I Gusti Lanang Kurniawan, Theophany Margareta Kusumadewi, Rima Cahyati Kuta, Putu Cicilia Rarasati Landapa, Raditya Rachman Lasmi, Anjely Doni Lazuardi Arsy, Lazuardi Lestari, Diayanti Tenti Maharani, Baiq Nadya Putri Maulida, Rizka Ayu Miraditi, Ni Komang Moestafa, Rizka Febriya Mutiara Syifa, R.R. Ditya Ni Nyoman Ayu, Susilawati Nisa Isneni Hanifa Nugraha, Gede Rama Hardy Nuralyza, Imasayu Nurhayati, Putri Nurhidayati Nurhidayati Ocktaviana Saputri, Legis Padma Puspita, Ni Made Sri Paerdoe, Lalu Dane Pemban Pambudi, Balqis Prudena Kurnia Paradhini, Tri Sastra Paradiesta, Andi Frieskha Naurah Paulus Sugianto, Paulus Pramudia, Prananda Rizki Pratiwi, Rukmanggana Satya Prawira, I Nyoman Dio Yudha Primayanti , Ika Primayanti, Ika Puspasari Mahadewi, Ni Made Putri, Atina Rizki Putri, Siti Noururrifqiyati Juna Qindi, Ahmad Sa’bi Al Rahmadini, Nasyada Fadhila Rahmat, Dwi Ramzi, Ali Rian Pramudya Riantiani, Baiq Prita Rifansha, Muhammad Ghifari Rusdi, Yudika Ilhami Safitri, Nasywa Aulia Sahidu, Muhammad Ghalvan Salsabila, Rika Kamila Sapta Wardhani, Indah Saraswati, Ni Wayan Citra Ayu Sepestian, Ghina Shadrina Rienti Setyawati, Indri Setyo Pambudi , Arif Shafitri, Shira Shalsabina Sugiono, Muhammad Rafly Adrian Suryani, ⁠Dini Tammasse, Jumraini Teguh Budi Wicaksono Ulfa Gea, Indah Ernanda Untari, Lania Pradiva Wahid, Isra' Wahyu Maharani, Amelia Wardi, Baiq Prita Riantiani Wardi, Bq. Prita Riantiani Widad, Najwa Wiracakra, I Gusti Lanang Krisna Yulianti, Arwinda Febri Zubaidi, Fitriannisa Faradina