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All Journal Majalah Kedokteran Bandung Althea Medical Journal Folia Medica Indonesiana Indonesian Journal of Science and Technology Health Notions Care : Jurnal Ilmiah Ilmu Kesehatan Biomolecular and Health Science Journal JOSSAE (Journal of Sport Science and Education) SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Majalah Biomorfologi (Biomorphology Journal) Multilateral: Jurnal Pendidikan Jasmani Dan Olahraga Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Indian Journal of Forensic Medicine & Toxicology Indonesian Andrology and Biomedical Journal Asian Journal of Health Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Sewagati Warta LPM Strada Jurnal Ilmiah Kesehatan (SJIK)

Rejeki, Purwo Sri

Departemen Ilmu Faal Dan Program Studi Magister Ilmu Kesehatan Olahraga, Fakultas Kedokteran Universitas Airlangga

Author-ID : 692834

Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Physical Condition Comparison between Female Athlete Indoor Hockey of East Java Team and National Team Fitry Nachamory Oemar; Irmantara Subagio; Hayuris Kinandita Setiawan; Purwo Sri Rejeki
Folia Medica Indonesiana Vol. 57 No. 1 (2021): March
Publisher : Universitas Airlangga

ABSTRACTThe purpose of this research is to describe the physical condition differences between female athletes indoor hockey of East Java Team and National Team. Data sampling is taken from 12 female athletes indoor hockey of PON 2016 with age range 17-28 years old and 12 athletes of indoor hockey of Indonesia’s National Team at SEA Games 2017 with age range 19-28 years old for comparison. Physical condition that measured is VO2max to represent endurance, abdominal muscle strength, speed and flexibility. Obtained data is then analyzed using SPSS. VO2max of East Java Team is (39.54±4.18) ml/kg/minute and for National Team is (43.43±7.59) ml/kg/minute (ρ=0.14). For abdominal muscle strength, East Java Team has (41.50±7.01) kg and National Team has (51.83±3.32) kg (ρ=0.00). For Speed, East Java Team has (3.59±0.30) second and National Team has (3.94±0.38) second (ρ=0.51). For Flexibility, East Java Team has (23.75±5.10) cm and National Team has (29.50±4.91) cm (ρ=0.01). From these data we can conclude that East Java Team physical condition is under National Team and it has significant differences at flexibility and abdominal muscle strength. Furthermore, optimal interventions are needed to improve both of those physical conditions.Keywords: hockey, endurance, flexibility, strength, speed

Effect of High Fat Diet on Body Weight, Visceral Fat Weight, and PPARG Expressions on Visceral Fat in Mice Cantika Putri Melyana; Purwo Sri Rejeki; Sony Wibisono Mudjanarko; Lilik Herawati; Mohammad Anam Al-Arif
Folia Medica Indonesiana Vol. 57 No. 3 (2021): September
Publisher : Universitas Airlangga

Obesity becomes a global epidemic nowadays. The high-fat diet is used as an alternative therapy for obesity. The optimal composition of a high-fat diet to reduce body weight is still unknown. This study aimed to determine which components of a high-fat diet can decrease body weight, visceral fat, and PPARG expression of visceral fat. This study was conducted at the Faculty of Veterinary Medicine, Universitas Airlangga, for three months by using a randomized post-test only control group design. Fifty male mice, 2-3 months old, 18-30 grams were adapted for one week given standard diet AIN93-M, then mice were divided into five groups, namely K1 (control group, 12% fat, 20% protein, 62% carbs); K2 (30% fat, 60% proteins, 0% carbs); K3 (45% fat, 45% protein, 0% carbs); K4 (60% fat, 30% protein, 0% carbs); and K5 (75% fat, 15% protein, 0% carbs). Bodyweight was measured before and after treatment, then the visceral fat and PPARG expressions were evaluated. Statistical comparisons were performed using Statistical Package for the Social Sciences (SPSS) software. After treatment, there were forty-three mice. The body weight and visceral fat weight of the mice with a high-fat diet were decreased. The most significant changes in body weight were in K4 with -9,60 ± 3,806 grams reduction. The bodyweight of mice in K5, slightly increased than K2-K4. This could be caused by the hormesis phenomenon. PPARG expressions decreased in groups with a high-fat diet but increased in K5. The composition of a high-fat diet in group K4 was the most optimal to decrease the body weight, visceral fat, and PPARG expressions in mice

The Role of Physical Exercise Intesity to Irisin Levels on Overweight and Obese Ido Nur Abdulloh; Sugiharto Sugiharto; Purwo Sri Rejeki
Folia Medica Indonesiana Vol. 57 No. 4 (2021): December
Publisher : Universitas Airlangga

Highlight:The differences in intensity physical exercise mechanisms associated with increased irisin secretion in overweight and obese subjects were determined.The secretion of irisin in the right intensity blood on obesity can be reduced because the calories were balanced. Abstract:Physical exercise is a non-pharmacological therapy that can secrete various types of myokines to treat obesity problems. One of the myokines that play a role is irisin. Irisin is a polypeptide hormone with 112 amino acid residues that are synthesized in skeletal muscle after the proteolytic precursor cleavage of fibronectin type III domain-containing protein 5 (FNDC5). The release of irisin in the blood circulation will stimulate the browning process in white fat tissue by inducing the expression of uncoupling protein-1 (UCP-1) through signaling p38 mitogen-activated protein kinase (p38-MAPK) to increase energy expenditure, thermogenesis and reduce fat accumulation. This study described the differences in intensity of physical exercise mechanisms associated with the increased irisin secretion in overweight and obese subjects. This study was designed as a literature review that involved studies from research journals in the last 10 years concerning humans from some databases, such as Science Direct, PubMed, and Google Scholar. This study also discussed the relationship between the intensity of physical exercise and the synthesis, secretion, circulation, and regulation of irisin in preventing obesity.

Effect of Long-Term Ketogenic Diet in Mice Serum Adiponectin Hamidah Kurniasari; Purwo Sri Rejeki; Hartono Kahar; Sri Sunarti
Folia Medica Indonesiana Vol. 58 No. 1 (2022): March
Publisher : Universitas Airlangga

Highlight:Adiponectin is an important protective factor for cardiovascular disease and increased insulin sensitivity.Ketogenic diet effect on adiponectin level in mice besides decrease weight gain was determined.The difference in serum adiponectin level and body weight is uncorrelated. Abstract:Ketogenic diet is a popular diet to reduce weight gain quickly. This diet has become a lifestyle . The ketogenic diet has been reported to affect adiponectin level, although it is still contraindicated. Adiponectin is a biomarker for metabolic disease that plays an important role as a protective factor for cardiovascular disease and increase insulin sensitivity. This study aimed to explore the effect of the ketogenic diet on adiponectin level in mice, besides decrease weight gain. This study was an experimental laboratory study with a randomized post-test-only control group design. Fourteen male mice (20-30 g) aged 2-3 months were divided randomly into K1 (n=7, standard diet) and K2 (n=7, ketogenic diet), were given diet for eight weeks, ad libitum. Body weight was measured at the pre and post-intervention, whereas adiponectin level were measured at the post-intervention using ELISA. The statistical analysis using SPSS version 16. The Shapiro Wilk test was used to determine normality, Independent T-Test was used to determine mean difference for normal distribution, Mann Whitney Test was used to determine mean difference for abnormal distribution, and Pearson Correlation was used to determine correlation. Difference (∆) of body weight on K1 (12.00±6.26) g, K2 (1.29±7.41) g with p=0.02. Serum adiponectin level of K1 (0.082±0.014) µg/ml and K2 (0.096±0.008) µg/ml with p=0.035. This study showed ketogenic diet-induced higher serum adiponectin level and slower weight gain. There is no correlation between the difference in body weight and serum adiponectin level (p=0.403).

Altered Ghrelin Secretion Pattern and Sense of Hunger by Providing Low and High Density Breakfast in Obese Female Adolescents Ni Luh Putu Ayu Putrisari Putri; Elyana Asnar; Purwo Sri Rejeki
Biomolecular and Health Science Journal Vol. 1 No. 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Introduction: Ghrelin has been recognized to have a major influence on energy balance. Hence, the discovery of various regulatory factors that control ghrelin secretion may have major implications for the development of drugs and diet control. This study aims to analyze differences in ghrelin secretion pattern and prevention of hunger in the provision of breakfast in low-calorie breakfast, low energy density and high energy density in obese female adolescents.Methods: Subjects were female students aged 18-22 years with a BMI=25 kg/m², receiving low-calorie breakfast with low (n=8) and high energy density (n=8). Before the breakfast, subjects fasted for 12 hours and were subjected to plasma ghrelin level and hunger measurement using visual analog scale (VAS). Breakfast was done at 08.00, divided into three parts and each was taken for 5 minutes. Measurement of plasma ghrelin was carried out again post prandial (PP) at 2 hours and 4 hours. VAS filling was done 1 hour PP, 2 hours PP, 3 hours PP, and 4 hours PP.Result: There were differences in plasma ghrelin level, but not significant. VAS 1 analysis of hunger (p=0.040) at 4 hours PP and VAS 3 of satiety (p=0.025) was significantly different at 3 hours PP. Conclusion: Food density did not affect the plasma ghrelin levels. Low density foods are more effective to prevent hunger in 4 hours PP and increases satiety in 3 hours PP.

Effect of Physical Training Towards Body Balance in Overweight Condition Purwo Sri Rejeki; Anita Faradilla Rahim; Rizki Eka Prasetya
Biomolecular and Health Science Journal Vol. 1 No. 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

An overweight individual has morphological changes in the muscle resulting functional impairment and can cause reduction in body balance system. Balance is an ability to maintain both static and dynamic equilibrium on various positions. An overweight person will experience a decrease in abdominal muscle strength and center of gravity shift. Physical training has positive effects to increase body balance. Stretching exercise maintains and increases the elasticity of muscle, tendon, fascia, ligament and joint motion and improve balance. Resistance exercise increases muscle performance which has benefit effect on balance system dynamically. The proprioceptive, an important part of balance maintenance to feel joint position or body when moving, can be improved by training that performed using balance board. Mechanoreceptor that is stimulated and the adaptation of the body's balance control that is influenced by balance board training results a good proprioceptive.

A Systematical Review of The Effect of Ketogenic Diet on Bcl-2 (B-cell lymphoma-2) Expression as An Apoptosis Marker in Cancer Treatment Vania Islamey Kusuma; Reny I’tishom; Ema Qurnianingsih; Purwo Sri Rejeki
Biomolecular and Health Science Journal Vol. 4 No. 2 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i2.30173

Introduction: Ketogenic diet seems to be in a great demand nowadays as a lot of people are interested in adopting it into their lifestyle. It is also found that the ketogenic diet shows several beneficial effects including cancer prevention. However, the detail mechanism still remains unknown. Therefore, this review was aimed to find out the effect of ketogenic diet on Bcl-2 (B-cell lymphoma-2) expression in cancer.Methods: We searched published literatures in PubMed through 2011-2020 using specific keywords. The literatures were filtered according to inclusion and exclusion criteria. Animal model, total sample size, underlying condition/inflammatory process occurs, details of the intervention/diet including diet contents in control group and high-fat group, and the duration of the intervention, Bcl-2 results, and p-value were extracted.Results: 7 studies were included in this review. Bcl-2 expression found decrease in 5 out of 6 studies. Similar result also obtained in Bcl-2 protein level, which measured by western blot. Bcl-2 protein level shows a decrease in 2 out of 3 studies.Conclusion: This review shows that high-fat diet that contained in ketogenic diet most likely lead to decrease in Bcl-2 expression. Therefore, indicating the ability of ketogenic diet to affect cancer progression by inducing apoptosis process.

Pengaruh moderate intensity continuous exercise terhadap kadar irisin serum pada wanita remaja obesitas Ido Nur Abdulloh; Sugiharto Sugiharto; Purwo Sri Rejeki
Multilateral : Jurnal Pendidikan Jasmani dan Olahraga Vol 20, No 1 (2021): February
Publisher : Lambung Mangkurat University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/multilateral.v20i1.10069

Tujuan penelitian ini untuk menganalisis pengaruh latihan dengan intensitas sedang yakni Moderate Intensity Continuous Exercise (MICE) terhadap peningkatan kadar irisin serum. Metode penelitian menggunakan true experimental-randomized pretest-posttest control group design dengan partisipasi 20 subjek wanita dengan Indeks Massa Tubuh (IMT) 25-35 kg/m2. Subjek secara random dibagi menjadi 2 kelompok, yakni CONT (n= 10, kontrol tanpa intervensi), dan MICE (n= 10, Moderate Intensity Continuous Exercise). Intervensi dilakukan secara continuous selama 30 menit. Intervensi dilakukan pukul 08.00-10.00 a.m. Pengambilan darah dilakukan pre-exercise dan 15 menit post-exercise. Pengukuran kadar irisin menggunakan metode ELISA. Teknik analisis data menggunakan t-test dan Analysis of Variance (ANOVA) dengan SPSS. Hasil penelitian menunjukkan terdapat peningkatan irisin serum pre dan post-test secara signifikan pada MICE (4,31±0,49 to 5,57±0,71) (p<0,05). Sementara pada CONT tidak terjadi perbedaan yang signifikan (4,35±0,69 to 4,39±0,64) (p>0,05). Berdasarkan hasil penelitian dapat disimpulkan bahwa MICE dapat meningkatkan kadar irisin serum pada wanita remaja obesitas saat setelah latihan fisik sehingga dapat dijadikan salah satu langkah terapi nonfarmakologis dalam menghambat permasalahan obesitas.

PEMASYARAKATAN DAN PELATIHAN OLAHRAGA ADAPTIF PADA ANAK BERKEBUTUHAN KHUSUS Purwo Sri Rejeki; Irfiansyah Irwadi; Misbakhul Munir; Hayuris Kinandita; Eka Arum Cahyaning Putri; Soffil Yudha Mulyadi; Septyaningrum Putri Purwoto
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 4 No. 1 (2020): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v4i1.2020.134-140

Inclusive children or children with special needs are those who have abnormalities in the process of growth or development; which can be physical, mental-intellectual, social, or emotional. The World Health Organization predicts that around 7% of the world's total children population is inclusive children. Exercise that are adapted and modified according to their needs, the type of abnormality and the ability of inclusive children are able to improve motor and sensory abilities so that they will improve their quality of life. The purpose of this activity is to increase the knowledge and skills of parents with inclusive children in implementing adaptive exercise for their children. The method used was seminar and training. Activity evaluation was carried out using questionnaire to observe the increase of knowledge. This activity was attended by 31 parents and 31 inclusive children, with the highest parents’ age range in 31-40 years, which is mothers 38.7%; 41.9% father. The age of expecting mothers of inclusive children mostly ranges from 31-40 years (35.5%). Increased knowledge about child development was 31% (pretest 68, posttest 91.8) and increased knowledge about adaptive sports was 72.18% (pretest 49.6, posttest 85.4).abstrakAnak Berkebutuhan Khusus (ABK) adalah anak yang dalam proses pertumbuhan atau perkembangannya mengalami kelainan atau penyimpangan; yang bisa berupa fisik, mental-intelektual, sosial, atau emosionalnya. Organisasi kesehatan dunia memprediksi sekitar 7% dari keseluruhan populasi anak dunia merupakan ABK. Olahraga yang diadaptasi dan dimodifikas sesuai dengan kebutuhan, jenis kelainan dan tingkat kemampuan ABK mampu memperbaiki kemampuan motoris dan sensoris sehingga akan meningkatkan kualitas hidupnya. Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan dan ketrampilan orang tua ABK dalam melatih olahraga adaptif buat anak-anaknya. Metode yang digunakan adalah seminar dan pelatihan. Evaluasi keberhasilan kegiatan dilakukan dengan kuesioner untuk melihat peningkatan pengetahuan. Kegiatan dihadiri oleh 31 orang tua dan 31 ABK, dengan rentang usia orang tua terbanyak di 31-40 tahun yaitu ibu 38,7%; ayah 41,9%. Usia ibu mengandung ABK terbanyak di rentang 31-40 tahun (35,5%). Peningkatan pengetahuan pada materi tumbuh kembang anak sebesar 31% (pretest 68, posttest 91,8) dan peningkatan pengetahuan materi olahraga adaptif sebesar 72,18% (pretest 49,6, posttest 85,4).

Correlation Between Diabetes Mellitus and Clinical Outcome of Patients with Acute Coronary Syndrome Underwent Percutaneus Coronary Intervention Therapy in Dr Soetomo Surabaya Hospital Alanna Sari Pratikto; I Gde Rurus Suryawan; Andrianto; Purwo Sri Rejeki
Indonesian Andrology and Biomedical Journal Vol. 1 No. 2 (2020): December
Publisher : Universitas Airlangga

Introduction: Coronary heart diseases continue to be the rising cause of mortality amongst Indonesian population, alongside with the increasing number of diabetic patients. The first line management of ACS is percutaneous coronary intervention (PCI), however previous have shown that diabetic patients have worse outcomes after therapy compared to non-diabetic patients. This study aims to compare the clinical outcomes between acute coronary syndrome (ACS) patients with diabetes and those without diabetes following percutaneus coronary intervention therapy. Methods: This study used cross sectional observational approach collecting records of ACS patients that underwent percutaneous coronary intervention in RSUD Dr Soetomo Surabaya from January 2018 to December 2019. Data regarding a patient’s age, gender, diabetic status, location of lesion, revascularization status, and clinical outcome were collected. Those with missing or incomplete data were excluded from the study. A total of 55 patients were included and analyzed, Results: amongst 55 patients that underwent PCI observed, 23 were diabetic and 32 were non-diabetic. Study has shown that diabetic patients have higher mortality rate compared to those without diabetes (6 patients vs. 1 patient, p=0,072) however based on the result analysis the p value of >0,05 showed no significant relationship between patients’ diabetic status and the clinical outcome following PCI therapy. Study has also shown that diabetic patients are more likely to undergo staged PCI (56,5%), than total revascularization PCI. Conclusion: Study has found that diabetic ACS has a higher mortality rate compared to those without diabetes, however analitycal studies found no significant relationship between the two variables. Further studies should be performed with higher number of patients to accurately investigate the relationship between diabetes melitus and PCI outcomes.

Co-Authors Abdurachman Adi Pranoto, Adi Al arif, Mohammad Anam Alanna Sari Pratikto Alanna Sari Pratikto Ananda, Naoval Diza Andrianto Andrianto Anita Faradilla Rahim Arifa Mustika Atika Atika Ayubi, Novadri Bambang Purwanto Bambang Purwanto Breklen Risal Ary Wibowo Cantika Putri Melyana Chabib Fachry Albab Chandra, Cecilia Felicia Cornelius Coli Cornelius Coli Deandra Maharani Widiatmaja Dedi Kuswandi Desi Rahmah Sari Desiana Merawati Dewangga Satria Sakti Kinasih Dewi Ratna Sari Dita Mega Utami Eka Arum Cahyaning Putri Eko Purwanto Elyana Asnar Fathil, Nur Ezza Fazleen Mohd Fathimatuzzahroh, Fathimatuzzahroh Fikri Sasongko Widyatama Filza Yulina Ade Fitry Nachamory Oemar Hakim, Faiq Amirul Hamidah Kurniasari Hamidah Kurniasari Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Hanna Goeanawan HARJANTO HARJANTO Hartono Kahar, Hartono Hasan, Helmia Hening Laswati Putra HERAWATI, LILIK Hermanto Tri Joewono Hermina Novida, Hermina Heryana, Achmad Yuniari I'tishom, Reny Ido Nur Abdulloh Ido Nur Abdulloh Imam Subadi Imam Susilo Iqbal Laksana Irmantara Subagio Irwadi, Irfiansyah Ismi Dian Meiliana Izzatunnisa, Nabilah Karimah, Azimatul Khairina Leonardo Lubis MEGANTARA, SANDRA Miftahul Nur Amaliyah Misbah Abdul Haris Nasution Alhanif Misbakhul Munir Mochammad Abdul Aziz, Mochammad Abdul Mohammad Anam Al-Ari Mubasyiroh, Nabila Ainaya Mufarrihul Ihsan Muhammad Adrian Khalfani Muhammad Al-Farouq Yufiro Akbar Muhammad Miftahussurur Ni Luh Putu Ayu Putrisari Putri Nova Sylviana Nur Ezza Fazleen Mohd Fathil Pambudi, A. Agam Haris Paulus Liben, Paulus Permana, Noah Jefferson Prasetya, Rizka Eka Qurnianingsih, Ema Raden Argarini Ray, Hamidie Ronald Daniel RizkaEka Prasetya Rizki Eka Prasetya Ronny Lesmana Rosdianto, Aziiz Mardanarian Rurus Suryawan S. Sugiharto Sakina Sakina Sakina Samsriyaningsih Handayani Saputro, Zanuar Bagus Saputro, Zanuar Bagus Sari, Gadis Meinar Savitri, Camilia Metadea Aji Septyaningrum Putri Purwoto Setiawan Setiawan Setiawan, Hayuris Kinandita Siti Khaerunnisa Soelistijo, Soebagijo Adi Soffil Yudha Mulyadi Sony Wibisono Sri Sunarti Sri Umijati Sugiharto Sugiharto Sugiharto Sugiharto Suhartati Suhartati Sukarno, Devitya Angielevi Sundari Indah Wiyasihati Suryawan, I Gde Rurus Susi Wahyuning Asih Susianti Susianti Suyoko, Andri Syahraya, Indira Texaga, Derryl Rasad Tinduh, Darmayanti Ummah, Fithriyah Cholifatul Unang Supratman Vania Islamey Kusuma Vita Murniati Tarawan Wardani, Tjitra Wardani, Tjitra Wardhani, Indrayuni Lukitra Yoshio Yamaoka, Yoshio Yudith Annisa Ayu Rezkitha, Yudith Annisa Ayu Yuliawati, Tri Hartini Yuni Susanti Pratiwi

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