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All Journal Majalah Kedokteran Bandung Althea Medical Journal Folia Medica Indonesiana Indonesian Journal of Science and Technology Health Notions Care : Jurnal Ilmiah Ilmu Kesehatan Biomolecular and Health Science Journal JOSSAE (Journal of Sport Science and Education) SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Majalah Biomorfologi (Biomorphology Journal) Multilateral: Jurnal Pendidikan Jasmani Dan Olahraga Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Indian Journal of Forensic Medicine & Toxicology Indonesian Andrology and Biomedical Journal Asian Journal of Health Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Sewagati Warta LPM Strada Jurnal Ilmiah Kesehatan (SJIK)

Rejeki, Purwo Sri

Departemen Ilmu Faal Dan Program Studi Magister Ilmu Kesehatan Olahraga, Fakultas Kedokteran Universitas Airlangga

Author-ID : 692834

Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Efek Suplementasi Omega 3 dan Latihan Fisik Terhadap Respon Inflamasi Novadri Ayubi; Bambang Purwanto; Purwo Sri Rejeki
Journal of Sport Science and Education Vol 5 No 2 (2020)
Publisher : Fakultas Ilmu Olahraga, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jossae.v5n2.p116-123

The aims of this article is to find out how the effects of omega 3 supplementation and physical exercise on the inflammatory response. The method applied is literature review. The results showed that omega 3 supplementation and regular exercise can reduce the inflammatory response that is not controlled. Inflammation is a protective response caused by injury or tissue damage. After physical activity the body will experienced an increase in inflammatory markers, namely C-Reactive Protein (CRP), Interleukin 1 (IL-1), Interleukin 6 (IL-6), Interleukin 10 (IL-10) and Tumor Necrosis Factor-a (TNF-a). Physical exercise, especially high-intensity eccentric exercises, will cause damage to muscle fibers and delayed muscle pain (DOMS) which results in disruption to muscle strength. Muscle pain is caused by an inflammatory process due to increased levels (TNF-a) in response to muscle damage. Inflammatory response that is not controlled can be controlled by giving omega 3 supplementation. It can be concluded that omega 3 supplementation and regular exercise are proven to reduce the inflammatory response that is not controlled, soto reduce the intensity of pain which support the performance in carrying out the exercise program.

HYPERBARIC OXYGEN THERAPY AS AN ADJUVANT TREATMENT IN HYDROCHLORIC ACID POISONING: A LITERATURE REVIEW Desi Rahmah Sari; Ismi Dian Meiliana; Dewangga Satria Sakti Kinasih; Hamidah Kurniasari; Purwo Sri Rejeki
Majalah Biomorfologi Vol. 33 No. 1 (2023): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v33i1.2023.52-58

Highlights1. In Indonesia, 18.8% of all suicides were the result of chemical poisoning, such as using hydrochloric acid (HCl).2. Hyperbaric Oxygen Therapy (HBOT) can be used as an emergency therapy for acute pathology or as a supplementary treatment for chronic illness. AbstractBackground: Suicide is the second most common cause of death and is a major public health problem in many countries globally. Chemical poisoning, such as hydrochloric acid (HCl), accounted for 18.8% of the total suicide cases in Indonesia. Through ingestion, this acid chemical contributes as the most common cause of swallowing injuries that can adversely affect the gastrointestinal mucosal through various pathological processes, primarily through an excessive inflammatory process. On the other hand, hyperbaric oxygen therapy (HBOT) has been widely used as a non-pharmacological therapy in many diseases, although its mechanism for reducing inflammation in HCl poisoning has remained unclear. Objective: This study aimed to provide a better understanding on hyperbaric oxygen's biomolecular mechanism as a potential adjuvant therapy in HCl poisoning. Discussion: HCl poisoning causes an excessive inflammatory process, leading to tissue hypoxia indicated by increased expression of Hypoxia Inducible Factor 1 (HIF-1). Hyperbaric oxygen therapy decreases the expression of HIF-1 through activation of the HIF-1 hydroxylation pathway via prolyl hydroxylase (PDH) in the proline pathway and HIF inhibiting factor (FIH) in the asparagine pathway. Reactivating both pathways will decrease HIF-1 activity, eventually reducing the ongoing inflammatory process. In addition, HBOT also plays a role in wound healing by stimulating angiogenesis growth factors. Conclusion: Hyperbaric oxygen therapy has the potential to be used as adjuvant therapy in HCl poisoning due to its beneficial effects on reducing inflammatory mediators and wound healing.

Potential Molecular Interaction of Nutmeg’s (Myristica fragrans) Active Compound via Activation of Caspase-3 Ronny Lesmana; Filza Yulina Ade; Yuni Susanti Pratiwi; Hanna Goeanawan; Nova Sylviana; Sandra Megantara; Susianti Susianti; Vita Murniati Tarawan; Purwo Sri Rejeki; Hamidie Ronald Daniel Ray; Unang Supratman
Indonesian Journal of Science and Technology Vol 7, No 1 (2022): IJOST: VOLUME 7, ISSUE 1, April 2022
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v7i1.45663

Myristica fragrans Houtt (belongs to the Myristicaceae family) is a Maluku Island (Indonesia) native plant. The seed of M. fragrans (Nutmeg) has been used for medicinal benefits. M. fragrans also has anti-cancer properties. The goal of this research was to use computer-aided drug design to investigate the in silico molecular docking of selected nutmeg compounds against Caspase-3. Molecular docking using Malegro Virtual Docker (MVD) software Ver 5.5 was performed to investigate binding complicated models to offer information on critical drug-receptor interactions. The most potent ligand was Licarin B, which had a docking score of -103.07 kcal/mol. The Licarin B structure formed several hydrogen bonds with Trp214 and Phe250. These findings imply that the nutmeg seed contains a prospective compound that could be a great anti-cancer agent.

“LET’S MOVE!” CAMPAIGN: EDUCATION AND STIMULATION OF PHYSICAL EXERCISE IN OLDER ADULTS Sundari Indah Wiyasihati; Hayuris Kinandita Setiawan; Purwo Sri Rejeki; Irfiansyah Irwadi
Jurnal Layanan Masyarakat Vol. 7 No. 1 (2023): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v7i1.2023.123-130

The increase in human life expectancy has led to an increase in the number of older adults worldwide, including in Indonesia. The aging population raises sarcopenia as a further problem in geriatric medicine. Sarcopenia is a syndrome characterized by progressive skeletal muscle mass and strength loss. This syndrome is associated with reduced quality of life, increased risk of falls, and even death. Physical exercise is the only effective intervention strategy. Therefore, we designed this community service program for socializing the healthy lifestyle of the elderly with one focus on physical exercise as a promotive, preventive, and curative effort on the incidence of sarcopenia in the elderly. The method chosen was socialization and educating fifty-two pre-elderly and elderly target partners regarding the healthy lifestyle for the older adults and elderly exercise activities as stimulation. The "Let's Move!" campaign that has been implemented can socialize and increase the knowledge of target partners regarding sarcopenia and physical exercise as an intervention for prevention and treatment. The formulation of the main guidelines for safe exercise for the elderly can be useful for target partners who generally already have one type of condition that limits their ability to carry out activities of daily living.

Optimalisasi Peran Kader Kesehatan dalam Edukasi dan Implementasi Gaya Hidup Sehat Lansia Sundari Indah Wiyasihati; Hayuris Kinandita Setiawan; Purwo Sri Rejeki; Lilik Herawati
Warta LPM WARTA LPM, Vol. 26, No. 2, April 2023
Publisher : Universitas Muhammadiyah Surakarta

The health problems of the elderly in the Puskesmas Industri, Gresik work area align with the Indonesian health phenomenon where the number of elderly and degenerative diseases is high. Health cadres training in the work area of the Puskesmas Industri is needed to optimize the role of cadres in educating and implementing a healthy lifestyle in older adults. The Community Partnership Program, focusing on health as part of goal 3 of The Sustainable Development Goals (SDGs), was carried out on September 1, 2022, and was attended by 57 cadres from 6 villages. Health information was provided as a provision for cadres to provide education to the public about the healthy lifestyle of the elderly. The results showed that there was an increase of 17,26 points (34,76%) after training. The lowest post-test results were on the topic of BMI and its interpretation, as well as physical activity in the elderly, so further action is needed. During FGD, the Elderly Health Book from the Ministry of Health of the Republic of Indonesia was introduced. The results of the FGD showed that the introduction of the Elderly Health Book should be continued so that health cadres can consistently use it. Health cadres have a significant role in realizing the elderly health program from the Indonesian Ministry of Health. This health cadre training has proven to be very necessary because it can increase understanding as a provision for cadres in providing education to the public regarding the healthy lifestyle of the elderly.

The Effect of Childhood Obesity on Psychomotor Behavior Muhammad Adrian Khalfani; Purwo Sri Rejeki; Sakina; Nur Ezza Fazleen Mohd Fathil
Folia Medica Indonesiana Vol. 59 No. 3 (2023): September
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/fmi.v59i3.45280

Childhood obesity is a complex problem, and its prevalence among school-age children has been found to have a greater impact on their physical well-being compared to their learning difficulties. In some cases, teachers or schools may not pay enough attention to issues that have the potential to affect or delay the psychomotor development of children. Therefore, this study aimed to provide enhanced comprehension regarding the effect of childhood obesity on psychomotor behavior. This study used a systematic review methodology to synthesize information regarding the effect of obesity on children's health and development. The information and data presented in this study were obtained from several scientific sources accessed through online libraries such as PubMed, ScienceDirect, and the Cochrane Library. A comprehensive search was conducted to identify scholarly publications, which resulted in a total of 815 papers published between 2013 and 2022. The selected papers exclusively consisted of original research articles that primarily focused on investigating the relationship between obesity in children aged 5–14 years and their psychomotor abilities and development outcomes. Following the screening process, five studies were found to meet the specified criteria. The findings of the selected studies revealed a substantial resemblance, specifically the correlation between childhood obesity and poor motor skills. Furthermore, the selected studies discovered that an increase in body fat is commonly associated with a rise in total body weight, or the relative body mass index (BMI), in both adults and children. Some studies demonstrated significant differences in the performance of diverse psychomotor variables according to children's BMI. According to the results of the studies, children with a higher BMI showed inferior performance in motor activities as a result of compromised body control and balance that inhibited the children's movement. This systematic review concludes that obesity has an effect on the psychomotor behavior of children.

EFFECT OF HEATED CANOLA OIL ON AORTA WALL THICKNESS IN RATS Aziz, Mochammad Abdul; I'tishom, Reny; Rejeki, Purwo Sri; Yuliawati, Tri Hartini
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.82-88

Highlights: 1. The use of re-heated cooking oil can give negative impact on health, especially on the cardiovascular system. 2. Unlike other types of cooking oil, repeated heating of canola oil did not show significant change in aortic wall thickness. Abstract Background: Structural alteration of blood vessels such as formation of atheroma or changes in the thickness of vessel walls, are heavily involved in pathogenesis of cardiovascular disease. Several studies have shown that canola oil has a positive effect on such diseases by reducing LDL and cholesterol levels. However, there may be several negative impacts on reheating canola oil upon administration, similar to other oils. Although canola oil can improve lipid profiles, studies related to how canola oil alters the structure of blood vessels are limited. Objective: The aim of this study was to investigate the effect of heated canola oil on intimal-to-medial thickness (IMT) of Thoracic aorta in high-fat diet rats. Material and Method: A total of 27 rats were divided into 3 groups, the K+, P1, and P2. Rats among the three groups were given a high-fat diet for 14 days, accompanied by consumption of canola oil without heating in the P1, and with repeated heating in the P2. Thoracic aorta was taken on the 15th day and then processed into histological preparations. IMT was measured using CellSens software on a microscope with a magnification of 400. The difference between groups was tested using the one-way ANOVA test on SPSS. Result: The mean and standard deviations of each group in a row were K+ (134.96 and 21.27) P1(132.04 and 27.30) and P2 (152.05 and 31.75). There was no significant difference in IMT between groups (p >0.05). However, the P2 group showed the highest mean of IMT. Conclusion: The consumption of canola oil with or without repeated heating did not result in the changes of the IMT in rats fed with a high-fat diet.

Correlation Between Family Cohesion and Recurrence in Schizophrenics at the dr. Soetomo Hospital Psychiatric Clinic Texaga, Derryl Rasad; Khairina; Purwo Sri Rejeki
Jurnal Psikiatri Surabaya Vol. 11 No. 1 (2022): May
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v11i1.24943

ABSTRACTBackground; Schizophrenia recurrence is caused by many factors, one of which is family factors. Family is very important for people with schizophrenia, where one of the roles and functions of the family is to provide an affective function to meet the psychosocial needs of family members in providing affection. Objective; This study was conducted with the aim of knowing the correlation between family cohesion and recurrence in schizophrenic patients at the Dr. Soetomo Hospital Psychiatric clinic. Methods; This research method using observational-analytic design with cross-sectional approach with a sample of schizophrenic patients at the Psychiatry Clinic of dr. Soetomo Hospital Surabaya in June-August 2020 which met the inclusion criteria. The variables studied were family cohesion and recurrence of schizophrenia. Samples were taken using total sampling with a sample size of 40 research subjects. Sampling was conducted at the dr. Soetomo Hospital Psychiatry Clinic. Data analysis was performed using the Spearman correlation analysis technique. Results; The results of the Spearman correlation analysis showed a correlation coefficient of -0.291 with a significance value of 0.69 (p> 0.05). Conclusion; It can be concluded that the relationship between the two variables is not unidirectional and there is no significant relationship between family cohesion and recurrence in schizophrenics at the dr. Soetomo Hospital Psychiatry Clinic. Keywords: Family Cohesion, Schizophrenia Recurrence, Schizophrenic Patients

The Correlation Between the Level of Depression and Religious Coping Among Medical Students Class of 2020 Universitas Airlangga Muhammad Al-Farouq Yufiro Akbar; Azimatul Karimah; Imam Susilo; Purwo Sri Rejeki
Jurnal Psikiatri Surabaya Vol. 13 No. 1 (2024): May
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v13i1.46284

Introduction: Medical students are at risk of developing depression due to their demanding workload and high expectations, which can impact their academic performance and cognitive function. To prevent severe complications, students must prioritize resources for mental health support, namely religious coping as a coping mechanism. Objective: The aim of this study is proof the correlation between depression levels and religious coping in medical students class of 2020 Universitas Airlangga Methods: This research is an observational analytic study with a cross-sectional design, and random sampling was used as a sampling method, totaling to 90 subjects. Variables used were religious coping and level of depression. The data was then analysed and prevalence, correlation coefficient and p-value were acquired. The research result would be considered significant if p <0.05. Result: Out of 90 students, 32 people (35.6%) are found to have a PHQ score more than 10, indicating depression. Severity was found mostly have moderate depression, which consisted of 12 people (13.3%). For religious coping, 84 people (93.3%) use positive religious coping, and 6 people (6.7%) use negative religious coping. The level of depression correlates with religious coping with a Pearson correlation of -0.450, indicating a negative correlation with a p-value less than 0.001. Conclusion: The prevalence of depression among medical students class of 2020 Universitas Airlangga is 35.6%. Level of depression in found to significantly correlates with religious coping with an opposing direction of correlation.

COMPARISON EFFECT OF CV 12, ST 36 AND ST 40 EA ON SHORT TERM ENERGY BALANCE REGULATION IN HIGH FAT DIET RAT Rejeki, Purwo Sri; Harjanto, Harjanto; Argarini, Raden; Subadi, Imam
Folia Medica Indonesiana Vol. 52 No. 3 (2016): JULY - SEPTEMBER 2016
Publisher : Universitas Airlangga

The aim of this study was to determine the comparative effects of EA (EA) on the CV12, ST36 and ST40 to weight gain prevention over the short-term regulation of energy balance. The study was conducted with a completely randomized design. Rats were divided into five groups: negative control group (no treatment, n=5), positive control (sham EA/back, n=5), EA CV 12 (n=6), EA ST 36 (n=6) and EA ST 40 (n=7). Rats were exposed to high-fat diet for two weeks and EA was simultaneously performed once daily, five days a week for two weeks with 2 Hz, for 10 minutes with continuous wave. Body weight, BMI, front limb circumference and rear were measured during study. Levels of blood glucose, cholesterol, triglycerides, LDL and HDL were measured at the end of the study; which reflects the short-term regulation of energy homeostasis. For weight loss, EA CV12, ST36 and ST40 group have lost weight significantly compared to the negative and positive control group. The ST40 group has a significant decrease than ST36 and CV12. The most significant decrease in BMI found in the ST40 group. EA did not affect blood glucose levels, but modulated blood lipid profile. In ST 40 group there was a significant decrease in cholesterol, LDL and triglycerides. EA at point ST 40 is potential in preventing increased body weight and BMI in rats exposed to high-fat diet compared to the CV 12 and ST 36. ST 40 is a point with a potential of lowering LDL and triglycerides serum so that it can play a role in the short term regulation of energy homeostasis but also in the prevention of dyslipidemia.

Co-Authors Abdurachman Adi Pranoto, Adi Al arif, Mohammad Anam Alanna Sari Pratikto Alanna Sari Pratikto Ananda, Naoval Diza Andrianto Andrianto Anita Faradilla Rahim Arifa Mustika Atika Atika Ayubi, Novadri Bambang Purwanto Bambang Purwanto Breklen Risal Ary Wibowo Cantika Putri Melyana Chabib Fachry Albab Chandra, Cecilia Felicia Cornelius Coli Cornelius Coli Deandra Maharani Widiatmaja Dedi Kuswandi Desi Rahmah Sari Desiana Merawati Dewangga Satria Sakti Kinasih Dewi Ratna Sari Dita Mega Utami Eka Arum Cahyaning Putri Eko Purwanto Elyana Asnar Fathil, Nur Ezza Fazleen Mohd Fathimatuzzahroh, Fathimatuzzahroh Fikri Sasongko Widyatama Filza Yulina Ade Fitry Nachamory Oemar Hakim, Faiq Amirul Hamidah Kurniasari Hamidah Kurniasari Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Hanna Goeanawan HARJANTO HARJANTO Hartono Kahar, Hartono Hasan, Helmia Hening Laswati Putra HERAWATI, LILIK Hermanto Tri Joewono Hermina Novida, Hermina Heryana, Achmad Yuniari I'tishom, Reny Ido Nur Abdulloh Ido Nur Abdulloh Imam Subadi Imam Susilo Iqbal Laksana Irmantara Subagio Irwadi, Irfiansyah Ismi Dian Meiliana Izzatunnisa, Nabilah Karimah, Azimatul Khairina Leonardo Lubis MEGANTARA, SANDRA Miftahul Nur Amaliyah Misbah Abdul Haris Nasution Alhanif Misbakhul Munir Mochammad Abdul Aziz, Mochammad Abdul Mohammad Anam Al-Ari Mubasyiroh, Nabila Ainaya Mufarrihul Ihsan Muhammad Adrian Khalfani Muhammad Al-Farouq Yufiro Akbar Muhammad Miftahussurur Ni Luh Putu Ayu Putrisari Putri Nova Sylviana Nur Ezza Fazleen Mohd Fathil Pambudi, A. Agam Haris Paulus Liben, Paulus Permana, Noah Jefferson Prasetya, Rizka Eka Qurnianingsih, Ema Raden Argarini Ray, Hamidie Ronald Daniel RizkaEka Prasetya Rizki Eka Prasetya Ronny Lesmana Rosdianto, Aziiz Mardanarian Rurus Suryawan S. Sugiharto Sakina Sakina Sakina Samsriyaningsih Handayani Saputro, Zanuar Bagus Saputro, Zanuar Bagus Sari, Gadis Meinar Savitri, Camilia Metadea Aji Septyaningrum Putri Purwoto Setiawan Setiawan Setiawan, Hayuris Kinandita Siti Khaerunnisa Soelistijo, Soebagijo Adi Soffil Yudha Mulyadi Sony Wibisono Sri Sunarti Sri Umijati Sugiharto Sugiharto Sugiharto Sugiharto Suhartati Suhartati Sukarno, Devitya Angielevi Sundari Indah Wiyasihati Suryawan, I Gde Rurus Susi Wahyuning Asih Susianti Susianti Suyoko, Andri Syahraya, Indira Texaga, Derryl Rasad Tinduh, Darmayanti Ummah, Fithriyah Cholifatul Unang Supratman Vania Islamey Kusuma Vita Murniati Tarawan Wardani, Tjitra Wardani, Tjitra Wardhani, Indrayuni Lukitra Yoshio Yamaoka, Yoshio Yudith Annisa Ayu Rezkitha, Yudith Annisa Ayu Yuliawati, Tri Hartini Yuni Susanti Pratiwi

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