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All Journal Jurnal Keperawatan Jiwa (JKJ): Persatuan Perawat Nasional Indonesia Jurnal Kesehatan Andalas Jurnal Kebidanan Dan Kesehatan Tradisional Pharmascience Biomedical Journal of Indonesia Biopsikososial: Jurnal Ilmiah Psikologi Fakultas Psikologi Universitas Mercubuana Jakarta Jurnal Penelitian Kesehatan Suara Forikes Jurnal Ilmiah Universitas Batanghari Jambi As-syifaa Jurnal Farmasi Jurnal Keperawatan Silampari JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Kreativitas PKM Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun NERS Jurnal Keperawatan Majalah Kedokteran Andalas Jurnal Farmasi Higea Bioscientia Medicina : Journal of Biomedicine and Translational Research Sumatera Medical Journal Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Indonesian Journal of Global Health research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Innovative: Journal Of Social Science Research Jurnal Penyakit Dalam Indonesia Media Penelitian dan Pengembangan Kesehatan NERS Jurnal Keperawatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Arina Widya Murni
Bagian Ilmu Penyakit Dalam, Fakultas Kedokteran, Universitas Andalas, Padang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Risk Factors for Sleep Disorders in Patients with Chronic Pain: A Meta-Analysis Yoerizta Ratu, An Nissa’; Arina Widya Murni
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 10 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i10.1100

Abstract

Background: Chronic pain and sleep disorders frequently co-occur, exacerbating each other in a vicious cycle. This meta-analysis aimed to identify and quantify risk factors associated with sleep disorders in individuals experiencing chronic pain. Methods: A systematic search of PubMed, Embase, Web of Science, and Cochrane Library databases was conducted from January 2018 to June 2024. Studies assessing sleep disorders (insomnia, obstructive sleep apnea, restless legs syndrome) in adults with chronic pain (non-cancer pain lasting >3 months) were included. Data on demographics, pain characteristics, sleep measures, and potential risk factors were extracted. Meta-analyses were performed using random-effects models to estimate pooled odds ratios (ORs) and 95% confidence intervals (CIs). Results: Twenty-seven studies (n = 12,453 participants) met the inclusion criteria. Chronic pain significantly increased the odds of having any sleep disorder (OR 2.83, 95% CI 2.19-3.65). Specific risk factors identified included: Female gender: OR 1.41 (95% CI 1.18-1.67); Higher pain intensity: OR 1.15 per 1-unit increase on a 0-10 scale (95% CI 1.08-1.23); Longer pain duration: OR 1.04 per year (95% CI 1.01-1.07); Presence of depression or anxiety: OR 2.32 (95% CI 1.85-2.91); Use of opioid medications: OR 1.58 (95% CI 1.23-2.04). Conclusion: Chronic pain is a substantial risk factor for sleep disorders. Gender, pain intensity, duration, comorbid mental health conditions, and opioid use emerged as modifiable risk factors. Targeted interventions addressing these factors may improve sleep outcomes in individuals with chronic pain.
Analysis Factors Related to Menstrual Disorders in Female Medical Students Situmorang, Risna Sari; Desmawati, Desmawati; Murni, Arina Widya
Jurnal Kebidanan dan Kesehatan Tradisional Jurnal Kebidanan dan Kesehatan Tradisional Volume 10 Number 2 Year 2025
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v10i2.577

Abstract

Background: Every woman can experience various disorders of menstruation, ranging from amenorrhea, oligomenorrhea, polymenorrhoea, hypomenorrhea, hypermenorrhoea, and dysmenorrhoea. This study aimed to elucidate the factors related to menstrual disorders in female students of the faculty of medicine at Universitas Andalas.  Methods: The purpose of this case-control study is to determine factors that increase the likelihood of developing a disease by comparing a group of cases with a group of controls, focusing on their exposure status. The respondents to this study were teenagers aged 18-21 years. A sample of 108 female students was taken using consecutive sampling. Data collection from anthropometric measurements and questionnaires menarche age, The International Physical Activity Questionnaire (IPAQ), Food Frequencies Questionnaire (FFQ) and Pittsburg Sleep Quality Index (PSQI). The Chi-Square test was used to analyze the data.  Results: The result showed no significant relationship between menarche age (p-value 0.420), stress levels (p-value 0.406), and physical activity (p-value 0.348), with menstrual disorders. There was a relationship between nutritional status (p-value 0.001), sleep quality (p-value 0.002), and eating patterns (p-value 0.001) with menstrual disorders. Conclusion: Diet is the factor most associated with menstrual disorders in female students, followed by sleep quality and nutritional status. The study recommends preventing menstrual disorders in female students by prioritising improvements in diet, sleep quality and nutritional status.
The Role of Antidepressants in a Malignancy Patient with Palliative Care: A Systematic Literature Review Yovanda, Ryandri; Arina Widya Murni; Widya Deli Satuti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 8 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i8.1051

Abstract

Background: Depression is a common complication in malignancy patients, and can worsen their quality of life and prognosis. Palliative care aims to improve the quality of life of patients with life-limiting illnesses, and antidepressants are often used in this context. Methods: This systematic review was conducted to evaluate the effectiveness of antidepressants in malignancy patients with palliative care. A literature search was conducted in three databases: PubMed, Cochrane, and ScienceDirect. Search terms included “Antidepressants,” “Malignancies,” and “Palliatives.” Results: Two studies met inclusion criteria: First study: Randomized controlled clinical trial evaluating the effectiveness of mirtazapine compared with escitalopram in malignant patients with depression. The results showed that mirtazapine was more effective in improving quality of life and reducing depressive symptoms compared with escitalopram. Second study: a study evaluating the effectiveness of antidepressants in elderly malignancy patients with depression. The results suggest that antidepressants may be effective in reducing depressive symptoms and improving quality of life, but further research is needed to confirm their effectiveness and safety. Conclusion: Available evidence suggests that antidepressants may be effective in treating depression in malignancy patients with palliative care. However, further research is needed to identify the most effective and safe antidepressants for this patient population.
Risk Factors for Sleep Disorders in Patients with Chronic Pain: A Meta-Analysis Yoerizta Ratu, An Nissa’; Arina Widya Murni
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 10 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i10.1100

Abstract

Background: Chronic pain and sleep disorders frequently co-occur, exacerbating each other in a vicious cycle. This meta-analysis aimed to identify and quantify risk factors associated with sleep disorders in individuals experiencing chronic pain. Methods: A systematic search of PubMed, Embase, Web of Science, and Cochrane Library databases was conducted from January 2018 to June 2024. Studies assessing sleep disorders (insomnia, obstructive sleep apnea, restless legs syndrome) in adults with chronic pain (non-cancer pain lasting >3 months) were included. Data on demographics, pain characteristics, sleep measures, and potential risk factors were extracted. Meta-analyses were performed using random-effects models to estimate pooled odds ratios (ORs) and 95% confidence intervals (CIs). Results: Twenty-seven studies (n = 12,453 participants) met the inclusion criteria. Chronic pain significantly increased the odds of having any sleep disorder (OR 2.83, 95% CI 2.19-3.65). Specific risk factors identified included: Female gender: OR 1.41 (95% CI 1.18-1.67); Higher pain intensity: OR 1.15 per 1-unit increase on a 0-10 scale (95% CI 1.08-1.23); Longer pain duration: OR 1.04 per year (95% CI 1.01-1.07); Presence of depression or anxiety: OR 2.32 (95% CI 1.85-2.91); Use of opioid medications: OR 1.58 (95% CI 1.23-2.04). Conclusion: Chronic pain is a substantial risk factor for sleep disorders. Gender, pain intensity, duration, comorbid mental health conditions, and opioid use emerged as modifiable risk factors. Targeted interventions addressing these factors may improve sleep outcomes in individuals with chronic pain.
Unraveling the Pathways: A Meta-Analysis Exploring the Biopsychosocial Mechanisms Linking Psychosomatic Symptoms and Systemic Lupus Erythematosus Ridho Pratama; Arina Widya Murni
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1201

Abstract

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by a complex interplay of biological, psychological, and social factors. Psychosomatic symptoms, such as depression, anxiety, and stress, are common in individuals with SLE and can significantly impact disease activity and overall well-being. This meta-analysis aims to explore the biopsychosocial mechanisms linking psychosomatic symptoms and SLE. Methods: A systematic search of PubMed, Embase, PsycINFO, and Web of Science databases was conducted from January 2013 to December 2024. Studies examining the relationship between psychosomatic symptoms and SLE were included. Data were extracted and analyzed using random-effects models to calculate pooled effect sizes. Results: Six studies met the inclusion criteria. The meta-analysis revealed a significant association between psychosomatic symptoms (depression, anxiety, and stress) and SLE disease activity (pooled effect size: r = 0.42, 95% CI: 0.31-0.53, p < 0.001). Furthermore, dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, pro-inflammatory cytokine activity, and impaired coping mechanisms emerged as key biopsychosocial pathways linking these factors. Conclusion: This meta-analysis highlights the significant impact of psychosomatic symptoms on SLE and identifies potential underlying mechanisms. These findings underscore the need for integrated biopsychosocial interventions in SLE management, targeting both physical and psychological well-being to improve patient outcomes.
THE DIFFERENCE IN TOTAL IMMUNOGLOBULIN E LEVELS AND EOSINOPHIL COUNTS AMONG ELDERLY INDIVIDUALS WITH AND WITHOUT ALLERGIC DISEASES Mulyana, Roza; Rio, Yugo Berri Putra; Raveinal, Raveinal; Martini, Rose Dinda; Harun, Harnavi; Asir, Taufik Rizkian; Fadrian, Fadrian; Murni, Arina Widya
Media Penelitian dan Pengembangan Kesehatan Vol. 35 No. 4 (2025): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v35i4.3114

Abstract

Penyakit alergi dapat terjadi pada lansia dengan gejala yang dapat memburuk akibat adanya proses imunosenesens. Kadar IgE total dan jumlah eosinofil dapat digunakan sebagai pemeriksaan tambahan untuk penyakit alergi. Penelitian ini bertujuan untuk mengetahui perbedaan kadar IgE total dan jumlah eosinofil pada lansia dengan dan tanpa penyakit alergi. Penelitian observational analitik ini dilakukan pada lansia usia 60-80 tahun di RSUP DR. M. Djamil Padang selama Januari–Juni 2024. Sampel dikelompokkan menjadi kelompok lansia dengan penyakit alergi dan kelompok lansia tanpa penyakit alergi. Pengambilan sampel dilakukan secara consecutive sampling, melibatkan 52 partisipan (masing-masing 26 dengan dan tanpa penyakit alergi).  Kadar IgE total dan jumlah eosinofil diperiksa dengan menggunakan sampel darah vena. Analisis data menggunakan uji Mann-Whitney. Hasil penelitian menunjukkan median kadar IgE total pada kelompok alergi sebesar 1.741,1 kIU/L (minimum 517,7 kIU/L; maksimum 4843 kIU/L), sedangkan kelompok non-alergi 177,1 kIU/L (minimum 14 kIU/L; maksimum 800 kIU/L). Median jumlah eosinofil pada kelompok alergi sebesar 378 sel/µL (min: 100; maks: 950), sedangkan kelompok non-alergi 61,5 sel/µL (min: 17; maks: 189). Terdapat perbedaan signifikan kadar IgE total dan jumlah eosinofil antara lansia dengan dan tanpa penyakit alergi (p<0,001). Lansia yang mengalami Alergi menunjukkan kadar IgE  dan jumlah eosinofil lebih tinggi dibandingkan lansia yang tidak  alergi.  
Co-Authors Abdiana Abdiana, Abdiana Adnil E Nurdin, Adnil E Adnil Edwin Nurdin Afriwardi Afriwardi Agustin, Nia Mitra Aisyah Elliyanti Alexander Kam Alexander Kam Alfitri Alfitri Amel Yanis Andriyan, Aric Frendi Anggi Setiawan Ardian Riza Ariani, Novita Ashal, Taufik Asir, Taufik Rizkian Athiutama, Ari Aulia, Annisa Beni Indra, Beni Bobbi Hemriyantton Dea Rika Putri Purba Dedy Almasdy Delmi Sulastri Desmawati Desmawati Dewi Eka Putri Dia Rofinda, Zelly Dia Dian Arfan As Bahri Dian Pertiwi Dian Pertiwi Diny Amenike Dita Nelvita Sari Dwitya Elvira, Dwitya Edison Edison Eldi Sauma Elizabeth Bahar Elmatris Sy Emil Huriani Emil Prasetyo Muhammad Ennesta Asri Erlina Rustam Ermayanti, Sabrina Eryati Darwin Esi Afriyanti Eti Yerizel Etriyel Myh Fadella, Annesa Fadhlurrahman Wide Putra Fadrian, Fadrian Gina Matahati Gina Sonia Gusya Liza, Rini Gusyaliza, Rini Hanum, Fathiya Juwita Harahap, Hana Yulia Rahmi Harun Harnavi Hasmiwati Havizur Rahman Havizur Rahman Helmi Arifin Hendra Permana Hendriati, Hendriati Husnil Wardiyah Indah Paradifa Sari Irlaks, Viton Surya Irwadi Irwadi Isnindiah Koerniati Julizar Julizar Julizar Julizar Liandhu Hakim, Sonya Lily Yanti Mardi, Tris Mar’atul Fadhilah Masrul Mona Rahmi Rulianti1 Muhamad Diva Caesar Muhammad Husnul Ikhsan Mustafa Noer Nasrul Zubir Nurhajjah, Sitti Oktarina, Elvi Puja Agung Antonius Putra Rio, Yugo Berri Rahman, Havizur Rahmat Syawqi Rahmat Syawqi Rahmatina B Herman Rahmi, Wahida Rahmy Nurdin RAVEINAL RAVEINAL Raveinal Raveinal Resti Yuliani Restu Susanti Rhandyka Rafli Ridho Berlianto Ridho Pratama Rihaliza Rihaliza Rika Fatmadona Rika Susanti Rina Gustia Rini Gusya Liza, Rini Gusya Rismawati Yaswir Rita Hamdani Rizanda Machmud Rose Dinda Martini Roza Kurniati Roza Kurniati Roza Mulyana Salma Nabilaputri Nadiaskara Saptino Miro Siti Nurhajjah Situmorang, Risna Sari Sri Wahyuni Tasman Tasman Tasman Tasman Tasman Tris Mardi Ulya Uti Fasrini Vania Aresti Yendrial Vilza Maharani Syahnel Vina Muspita Viton Surya Irlaks Vokal Furkano Wardhy Arief Hidayat Widya Deli Satuti Wijaya, Harwin Winda Resvi Juliana Yanni, Mefri Yaslinda Yaunin Yevri Zulfiqar Yoerizta Ratu, An Nissa’ Yovanda, Ryandri Yugo Berri Putra Rio Yui Muya Yulistini Yulistini, Yulistini Yuriko Andre Yutika Jasvita Zelly Dia Rofinda